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1952-15-4 | 4-DiphenylacetoXy-N-methylpiperidine Methiodide
CAS No: 1952-15-4 Catalog No: AG003LAR MDL No:
Product Description
Catalog Number:
AG003LAR
Chemical Name:
4-DiphenylacetoXy-N-methylpiperidine Methiodide
CAS Number:
1952-15-4
Molecular Formula:
C21H26INO2
Molecular Weight:
451.3411
IUPAC Name:
(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate;iodide
InChI:
InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
InChI Key:
WWJHRSCUAQPFQO-UHFFFAOYSA-M
SMILES:
CN1CCC(CC1)OC(=O)C(c1ccccc1)c1ccccc1.IC
Properties
Complexity:
380
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
451.101g/mol
Formal Charge:
0
Heavy Atom Count:
25
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
451.348g/mol
Monoisotopic Mass:
451.101g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
26.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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| Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds. | European journal of medicinal chemistry 20130501 |
| Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response. | International immunopharmacology 20121101 |
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| Expression of muscarinic receptors by human macrophages. | The European respiratory journal 20120301 |
| 1,4-dioxane, a suitable scaffold for the development of novel M₃ muscarinic receptor antagonists. | Journal of medicinal chemistry 20120223 |
| Effects of neostigmine on bronchoconstriction with continuous electrical stimulation in rats. | Journal of anesthesia 20120201 |
| Activation of M3 muscarinic receptor and Ca²⁺ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum. | Journal of ethnopharmacology 20120106 |
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| Role of various subtypes of muscarinic cholinergic receptors in the development of posthemorrhagic abnormalities in systemic and portal circulation in rats. | Bulletin of experimental biology and medicine 20120101 |
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| Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury. | Brain research bulletin 20110810 |
| Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons. | Cellular signalling 20110601 |
| M1 and M3 muscarinic receptors mediate relaxation and contraction in canine nasal veins. | American journal of rhinology & allergy 20110101 |
| The effect of boric acid on acethylcholine, bethanechol and potasssium-evoked responses on ileum of rat. | Autonomic & autacoid pharmacology 20110101 |
| Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships. | Bioorganic & medicinal chemistry 20101101 |
| M₃muscarinic receptors mediate acetylcholine-induced pulmonary vasodilation in pulmonary hypertension. | Bioscience trends 20101001 |
| Cholinergic autoantibodies from primary Sjögren's syndrome modulate submandibular gland Na+/K+-ATPase activity via prostaglandin E2 and cyclic AMP. | European journal of oral sciences 20100401 |
| Opening of ATP-sensitive potassium channel by insulin in the brain-induced insulin secretion in Wistar rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100201 |
| Distinct roles of cholinergic receptors in small cell lung cancer cells. | Anticancer research 20100101 |
| Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells. | American journal of physiology. Gastrointestinal and liver physiology 20091201 |
| Muscarinic receptor antagonism at the spinal cord level causes inhibitory effects on male rat sexual behavior. | Behavioural brain research 20091105 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| High spatial resolution studies of muscarinic neuroeffector junctions in mouse isolated vas deferens. | Neuroscience 20090915 |
| The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models. | Journal of cardiovascular pharmacology and therapeutics 20090901 |
| Spinal cholinergic mechanism of the relieving effects of electroacupuncture on cold and warm allodynia in a rat model of neuropathic pain. | The journal of physiological sciences : JPS 20090701 |
| Muscarinic receptor-mediated nitric oxide release in a K562 erythroleukaemia cell line. | Autonomic & autacoid pharmacology 20090701 |
| Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine. | Molecules and cells 20090531 |
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| Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats. | Clinical and experimental pharmacology & physiology 20090501 |
| Dual radiotracer analysis of cholinergic neuronal changes in prediabetic mouse pancreas. | Diabetes technology & therapeutics 20090201 |
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| Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts. | The journal of medical investigation : JMI 20090101 |
| Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder. | Brain research bulletin 20081216 |
| Levels of [(3)H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1. | Schizophrenia research 20081201 |
| Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake. | British journal of pharmacology 20081201 |
| Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism. | Canadian journal of physiology and pharmacology 20081201 |
| cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. | Journal of medicinal chemistry 20081127 |
| Refractoriness of the sheep superior vena cava myocardial sleeve. | Experimental biology and medicine (Maywood, N.J.) 20081101 |
| Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway. | The Journal of endocrinology 20081101 |
| [Role of ventricular M3 receptor in arrhythmia resulted from cerebral-cardiac syndrome]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080801 |
| Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. | Journal of medicinal chemistry 20080724 |
| Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer's disease patients with psychosis. | Psychopharmacology 20080601 |
| Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness. | European journal of pharmacology 20080428 |
| Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux. | Life sciences 20080423 |
| Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats. | Neuroscience letters 20080328 |
| Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism. | European journal of pharmacology 20080317 |
| Subtype-selective blockade of cardiac muscarinic receptors inhibits vagal chronotropic responses in cats. | Pflugers Archiv : European journal of physiology 20080201 |
| Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment. | Clinical and experimental pharmacology & physiology 20080201 |
| Functional expression of M3, a muscarinic acetylcholine receptor subtype, in taste bud cells of mouse fungiform papillae. | Chemical senses 20080101 |
| Involvement of the lymphocytic muscarinic acetylcholine receptor in methylmercury-induced c-Fos expression and apoptosis in human leukemic T cells. | Journal of toxicology and environmental health. Part A 20080101 |
| [Coronary vasodilatation induced by acetylcholine in the isolated hearts of guinea pig and mice: differential contributions of nitric oxide and postacyclin]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
| Novel oxotremorine-related heterocyclic derivatives: Synthesis and in vitro pharmacology at the muscarinic receptor subtypes. | Bioorganic & medicinal chemistry 20071215 |
| Anti-brain cholinergic auto antibodies from primary Sjögren syndrome sera modify simultaneously cerebral nitric oxide and prostaglandin biosynthesis. | International immunopharmacology 20071205 |
| Cholinergic innervation of the guinea-pig isolated vas deferens. | Naunyn-Schmiedeberg's archives of pharmacology 20071201 |
| Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system. | BJU international 20070901 |
| Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction. | European urology 20070801 |
| Increase in cochlear microphonic potential after toluene administration. | Hearing research 20070801 |
| Roles of muscarinic receptor subtypes in small intestinal motor dysfunction in acute radiation enteritis. | American journal of physiology. Gastrointestinal and liver physiology 20070701 |
| Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway. | European journal of pharmacology 20070601 |
| Autonomic involvement in the permanent metabolic programming of hyperinsulinemia in the high-carbohydrate rat model. | American journal of physiology. Endocrinology and metabolism 20070501 |
| Muscarinic receptor-independent activation of cyclic adenosine monophosphate-dependent protein kinase in rostral ventrolateral medulla underlies the sympathoexcitatory phase of cardiovascular responses during mevinphos intoxication in the rat. | Shock (Augusta, Ga.) 20070501 |
| Cardiovascular effects of carbachol microinjected into the bed nucleus of the stria terminalis of the rat brain. | Brain research 20070427 |
| Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero. | American journal of obstetrics and gynecology 20070401 |
| Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. | Journal of agricultural and food chemistry 20070321 |
| In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows. | American journal of veterinary research 20070301 |
| Endocannabinoids mediate muscarine-induced synaptic depression at the vertebrate neuromuscular junction. | The European journal of neuroscience 20070301 |
| Segment-dependent expression of muscarinic acetylcholine receptors and G-protein coupling in the equine respiratory tract. | Veterinary research communications 20070201 |
| In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat. | Basic & clinical pharmacology & toxicology 20070201 |
| Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice. | European journal of pharmacology 20070112 |
| Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle. | Journal of pharmacological sciences 20070101 |
| Messenger RNA levels and binding sites of muscarinic acetylcholine receptors in gastrointestinal muscle layers from healthy dairy cows. | Journal of receptor and signal transduction research 20070101 |
| Release of glutamate by the embryonic spinal motoneurons of rat positively regulated by acetylcholine through the nicotinic and muscarinic receptors. | Neurochemistry international 20061101 |
| Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. | Naunyn-Schmiedeberg's archives of pharmacology 20061101 |
| Muscarinic regulation of neonatal rat bladder spontaneous contractions. | American journal of physiology. Regulatory, integrative and comparative physiology 20061001 |
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| Agonist and antagonist sensitivity of non-selective cation channel currents evoked by muscarinic receptor stimulation in bovine ciliary muscle cells. | Autonomic & autacoid pharmacology 20060701 |
| Muscarinic cholinoceptor activation modulates DNA synthesis and CD40 expression in fibroblast cells. | Autonomic & autacoid pharmacology 20060701 |
| Cardiac activity and blood pressure in rats during selective blockade of various subtypes of muscarinic cholinoceptors. | Bulletin of experimental biology and medicine 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Neural regulation of slow-wave frequency in the murine gastric antrum. | American journal of physiology. Gastrointestinal and liver physiology 20060301 |
| Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine. | Journal of pharmacological sciences 20060301 |
| Increase of insulin secretion by ginsenoside Rh2 to lower plasma glucose in Wistar rats. | Clinical and experimental pharmacology & physiology 20060101 |
| Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain. | Anesthesiology 20051201 |
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| M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice. | British journal of pharmacology 20050901 |
| The anti-inflammatory effect of peripheral bee venom stimulation is mediated by central muscarinic type 2 receptors and activation of sympathetic preganglionic neurons. | Brain research 20050712 |
| Neuronal nitric oxide synthase activity in rat urinary bladder detrusor: participation in M3 and M4 muscarinic receptor function. | Autonomic & autacoid pharmacology 20050701 |
| Postjunctional modulation by muscarinic M2 receptors of responses to electrical field stimulation of rat detrusor muscle preparations. | Autonomic & autacoid pharmacology 20050701 |
| Regional differences in cholinergic regulation of potassium current in feline esophageal circular smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20050601 |
| Signal transduction underlying carbachol-induced PGE2 generation and cox-1 mRNA expression of rat brain. | Neuropharmacology 20050401 |
| Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle. | The Journal of pharmacology and experimental therapeutics 20050201 |
| M3-R/IK(M3)--a new target of antiarrhythmic agents. | Yao xue xue bao = Acta pharmaceutica Sinica 20050101 |
| [The role of a type of m-choline receptors in realization of vagal influences on cardiac rhythm and conduction]. | Kardiologiia 20050101 |
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| Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice. | European journal of pharmacology 20041128 |
| Alterations in the muscarinic M1 and M3 receptor gene expression in the brain stem during pancreatic regeneration and insulin secretion in weanling rats. | Life sciences 20040924 |
| Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation. | American journal of physiology. Gastrointestinal and liver physiology 20040901 |
| Functional characterization of muscarinic receptor subtypes in human duodenal secretion. | Acta physiologica Scandinavica 20040901 |
| Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits. | The Chinese journal of physiology 20040630 |
| Effects of anticholinergic drugs selective for muscarinic receptor subtypes on prepulse inhibition in mice. | European journal of pharmacology 20040525 |
| Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea. | Anesthesia and analgesia 20040501 |
| [Relationship between M3 receptor and myocyte apoptosis induced by acute myocardial infarction]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040501 |
| Regulation of rat mesencephalic GABAergic neurones through muscarinic receptors. | The Journal of physiology 20040415 |
| Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src. | Circulation research 20040319 |
| Mechanism of action of the cisapride-induced vasodilatation in renal vasculature of rat. | The Indian journal of medical research 20040301 |
| Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill. | BMC neuroscience 20040101 |
| Long vasodilator reflexes projecting through the myenteric plexus in guinea-pig ileum. | The Journal of physiology 20031215 |
| Projections from the caudal part to the rostral part of the lateral septal area mediate blood pressure increase. | Brain research bulletin 20030930 |
| Activation of muscarinic receptors in rat subfornical organ neurones. | Journal of neuroendocrinology 20030801 |
| Change in muscarinic modulation of transmitter release in the rat urinary bladder after spinal cord injury. | Neurochemistry international 20030701 |
| Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells. | Investigative ophthalmology & visual science 20030601 |
| Brain muscarinic receptor subtypes mediating water intake and Fos following cerebroventricular administration of bethanecol in rats. | Psychopharmacology 20030501 |
| Castration decreases amylase release associated with muscarinic acetylcholine receptor downregulation in rat parotid gland. | British journal of pharmacology 20030501 |
| Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats. | European journal of pharmacology 20030404 |
| A mechanism for rapacuronium-induced bronchospasm: M2 muscarinic receptor antagonism. | Anesthesiology 20030401 |
| The M4 muscarinic receptor-selective effects on keratinocyte crawling locomotion. | Life sciences 20030328 |
| Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA2 by m3 and m2 receptors. | American journal of physiology. Gastrointestinal and liver physiology 20030301 |
| Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig. | Experimental & molecular medicine 20030227 |
| Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. | American journal of respiratory cell and molecular biology 20030201 |
| CCK regulates pancreatic enzyme secretion via short duodenal-pancreatic reflexes in pigs. | Scandinavian journal of gastroenterology 20030201 |
| Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats. | Brain research bulletin 20030130 |
| Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol. | Neuroscience 20030101 |
| The colon-selective spasmolytic otilonium bromide inhibits muscarinic M(3) receptor-coupled calcium signals in isolated human colonic crypts. | British journal of pharmacology 20021201 |
| Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus. | American journal of physiology. Lung cellular and molecular physiology 20021101 |
| Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats. | Autonomic neuroscience : basic & clinical 20020930 |
| Release of acetylcholine by Die-Huang-Wan to enhance insulin secretion for lowering plasma glucose in Wistar rats. | Autonomic neuroscience : basic & clinical 20020930 |
| Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase. | Cardiovascular research 20020815 |
| Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland. | European journal of pharmacology 20020329 |
| [The effects of the antagonists of muscarinic acetylcholine receptor subtypes in rat brain on urinary bladder contraction]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20020301 |
| Cholinergic and serotonergic activities are required in triggering conditioned NK cell response. | Journal of neuroimmunology 20020201 |
| The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation. | The Journal of urology 20020101 |
| Coupling of M(2) muscarinic receptors to Src activation in cultured canine colonic smooth muscle cells. | American journal of physiology. Gastrointestinal and liver physiology 20020101 |
| On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder. | European journal of pharmacology 20011012 |
| Characterization of muscarinic acetylcholine receptors in the rat epididymis. | Biology of reproduction 20011001 |
| Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle. | British journal of pharmacology 20010801 |
| Effects of cholinergic agents on the vasopressin-mediated water transport in the isolated toad bladder. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010601 |
| Expression of multiple subtypes of muscarinic receptors and cellular distribution in the human heart. | Molecular pharmacology 20010501 |
| The role of cholinergic and peptidergic pathways in the regulation of pancreatic exocrine function during postnatal development in pigs. | Experimental physiology 20010501 |
| Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry. | British journal of pharmacology 20010401 |
| Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists. | Neurochemical research 20010401 |
| Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes. | The Journal of biological chemistry 20010223 |
| [Cardiac-hemodynamic effects of M3 receptor agonist on rat and rabbit hearts]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010201 |
| Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands. | American journal of physiology. Lung cellular and molecular physiology 20010101 |
| A dose-response study of anticholinesterase drugs on contractile and phosphatidylinositol responses of rat trachea. | Anesthesia and analgesia 20010101 |
| Mechanisms of acetylcholine-induced vasorelaxation in high K+-stimulated rabbit renal arteries. | The Journal of veterinary medical science 20010101 |
| Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs. | Experimental animals 20010101 |
| A method for measurement of muscarinic receptor-mediated responses in dissociated single colon longitudinal smooth muscle cells. | Journal of pharmacological and toxicological methods 20010101 |
| Cholinergic stimulation of rat acinar cells increases c-fos and c-jun expression via a mitogen-activated protein kinase-dependent pathway. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20010101 |
| The minor population of M3-receptors mediate contraction of human detrusor muscle in vitro. | Journal of autonomic pharmacology 20010101 |
| Calcium signaling and c-Fos gene expression via M3 muscarinic acetylcholine receptors in human T- and B-cells. | Japanese journal of pharmacology 20001001 |
| M3 muscarinic receptor activation of a delayed rectifier potassium current in canine atrial myocytes. | Life sciences 19990101 |
| Interaction of neuromuscular blocking drugs with recombinant human m1-m5 muscarinic receptors expressed in Chinese hamster ovary cells. | British journal of pharmacology 19981101 |
| Identification of muscarinic receptor subtypes in RINm5F cells by means of polymerase chain reaction, subcloning, and DNA sequencing. | Diabetes 19970901 |
| Characterisation of [3H]-darifenacin as a novel radioligand for the study of muscarinic M3 receptors. | Journal of receptor and signal transduction research 19970101 |
| Muscarinic antagonists microinjected into the subthalamic nucleus decrease muscular rigidity in reserpinized rats. | Neuroscience letters 19960809 |
| Assessment of the muscarinic receptor subtypes involved in pilocarpine-induced seizures in mice. | Neuroscience letters 19940227 |
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