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Home > Other Building Blocks > 1927-31-7
CAS No: 1927-31-7 Catalog No: AG002G7Y MDL No:MFCD00080335
Title | Journal |
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Effects of substitutions at the 4' and 2 positions on the bioactivity of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. | Antimicrobial agents and chemotherapy 20131201 |
Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance. | Chemical research in toxicology 20120820 |
Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. | Structure (London, England : 1993) 20120808 |
Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase. | Bioorganic & medicinal chemistry letters 20120615 |
Non-infectious lung disease in patients with adenosine deaminase deficient severe combined immunodeficiency. | Journal of clinical immunology 20120601 |
Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates. | Current protocols in nucleic acid chemistry 20120601 |
Formation of dAMP-glycerol and dAMP-Tris derivatives by Thermococcus kodakaraensis DNA primase. | The Journal of biological chemistry 20120511 |
Altered nucleotide cofactor-dependent properties of the mutant [S240K]RecA protein. | Biochemical and biophysical research communications 20120511 |
How conformational dynamics of DNA polymerase select correct substrates: experiments and simulations. | Structure (London, England : 1993) 20120404 |
Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states. | Biochimica et biophysica acta 20120401 |
DNA building blocks: keeping control of manufacture. | Critical reviews in biochemistry and molecular biology 20120201 |
Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction. | PloS one 20120101 |
A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility. | PloS one 20120101 |
Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation. | PloS one 20120101 |
VS411 reduced immune activation and HIV-1 RNA levels in 28 days: randomized proof-of-concept study for antiviral-hyperactivation limiting therapeutics. | PloS one 20120101 |
Importance of the C2, N7, and C8 positions to the mutagenic potential of 8-Oxo-2'-deoxyguanosine with two A family polymerases. | Biochemistry 20111213 |
Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. | Molecular pharmacology 20111201 |
Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. | Journal of molecular and cellular cardiology 20111201 |
Refueling the heart: Using 2-deoxy-ATP to enhance cardiac contractility. | Journal of molecular and cellular cardiology 20111201 |
Kinetic mechanism of active site assembly and chemical catalysis of DNA polymerase β. | Biochemistry 20111115 |
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. | Nature 20111106 |
Development of quantitative DNA cleavage assay for XPG endonuclease activity using endogenous nuclear proteins in human cell lines. | Oncology reports 20111101 |
Highly fluorescent 5-(5,6-dimethoxybenzothiazol-2-yl)-2'-deoxyuridine 5'-triphosphate as an efficient substrate for DNA polymerases. | Chembiochem : a European journal of chemical biology 20111017 |
Optimization of pyrosequencing reads by superior successive incorporation efficiency of improved 2'-deoxyadenosine-5'-triphosphate analogs. | Analytical biochemistry 20110901 |
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides. | European journal of medicinal chemistry 20110901 |
Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. | Cell death & disease 20110901 |
Alzheimer's risk variants in the clusterin gene are associated with alternative splicing. | Translational psychiatry 20110701 |
Mechanism of action of pentostatin and cladribine in hairy cell leukemia. | Leukemia & lymphoma 20110601 |
Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. | Nature structural & molecular biology 20110301 |
Novel roles for hypoxia and prostaglandin E2 in the regulation of IL-8 during endometrial repair. | The American journal of pathology 20110301 |
Real-time bioluminescent assay for inhibitors of RNA and DNA polymerases and other ATP-dependent enzymes. | Analytical biochemistry 20110115 |
3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase. | Organic & biomolecular chemistry 20110107 |
Remodeling of the metabolome during early frog development. | PloS one 20110101 |
Treatment of hepatitis B in decompensated liver cirrhosis. | International journal of hepatology 20110101 |
Roles of oxidative stress, apoptosis, PGC-1α and mitochondrial biogenesis in cerebral ischemia. | International journal of molecular sciences 20110101 |
Concurrent radiotherapy and chemotherapy for locally advanced squamous cell carcinoma of the head and neck. | Head & neck oncology 20110101 |
Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon. | Analytical chemistry 20101201 |
Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles. | Analytical chemistry 20100901 |
Abacavir and tenofovir disoproxil fumarate co-administration results in a nonadditive antiviral effect in HIV-1-infected patients. | AIDS (London, England) 20100313 |
Use of clofarabine for acute childhood leukemia. | Biologics : targets & therapy 20100101 |
The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA. | BMC biology 20100101 |
Hydrolysis of aspartic acid phosphoramidate nucleotides: a comparative quantum chemical study. | Physical chemistry chemical physics : PCCP 20090907 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides. | Antimicrobial agents and chemotherapy 20090901 |
Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment. | Biochemistry 20090811 |
Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. | Biochemistry 20090602 |
Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. | Organic letters 20090507 |
Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells. | Journal of proteomics 20090502 |
In vitro supplementation with dAMP/dGMP leads to partial restoration of mtDNA levels in mitochondrial depletion syndromes. | Human molecular genetics 20090501 |
DNA synthesis across an abasic lesion by human DNA polymerase iota. | Structure (London, England : 1993) 20090415 |
Y-Family DNA polymerases may use two different dNTP shapes for insertion: a hypothesis and its implications. | Journal of molecular graphics & modelling 20090401 |
Factors affecting plasmid production in Escherichia coli from a resource allocation standpoint. | Microbial cell factories 20090101 |
Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence. | Molecular neurodegeneration 20090101 |
Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID). | Biologics : targets & therapy 20090101 |
Automated mass action model space generation and analysis methods for two-reactant combinatorially complex equilibriums: an analysis of ATP-induced ribonucleotide reductase R1 hexamerization data. | Biology direct 20090101 |
Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases. | Journal of immunology (Baltimore, Md. : 1950) 20081201 |
Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes. | Acta crystallographica. Section D, Biological crystallography 20081101 |
Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA. | Organic & biomolecular chemistry 20081021 |
Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase. | Protein science : a publication of the Protein Society 20080901 |
Increased intracellular [dATP] enhances cardiac contraction in embryonic chick cardiomyocytes. | Journal of cellular biochemistry 20080815 |
Development of bioluminescent pyrophosphate assay using pyruvate phosphate dikinase and its application to single-nucleotide polymorphism analysis. | Analytical biochemistry 20080801 |
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. | Biochemistry 20080729 |
Determinants of vaccinia virus early gene transcription termination. | Virology 20080620 |
Characterization of a dITPase from the hyperthermophilic archaeon Thermococcus onnurineus NA1 and its application in PCR amplification. | Applied microbiology and biotechnology 20080601 |
Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis. | Nucleosides, nucleotides & nucleic acids 20080601 |
Hepatitis C virus helicase/NTPase: an efficient expression system and new inhibitors. | Biochemistry. Biokhimiia 20080601 |
Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation. | Biochemistry 20080415 |
Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. | Biochemistry 20080304 |
Apoptosome assembly. | Methods in enzymology 20080101 |
Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine. | BMC cancer 20080101 |
Surface-initiated enzymatic polymerization of DNA. | Langmuir : the ACS journal of surfaces and colloids 20071106 |
Analysis of dideoxyadenosine triphosphate by CE with fluorescence detection. I. Derivatization through the phosphate group. | Electrophoresis 20071101 |
A 9-yr evaluation of carrier erythrocyte encapsulated adenosine deaminase (ADA) therapy in a patient with adult-type ADA deficiency. | European journal of haematology 20071001 |
Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis. | Structure (London, England : 1993) 20070801 |
Elastic behavior of RecA-DNA helical filaments. | Journal of molecular biology 20070727 |
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. | Nature 20070531 |
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. | Biophysical journal 20070501 |
The apoptosome: signalling platform of cell death. | Nature reviews. Molecular cell biology 20070501 |
The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP. | Journal of virology 20070401 |
Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity. | Journal of molecular biology 20070309 |
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. | Journal of molecular biology 20070119 |
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides. | BMC structural biology 20070101 |
Simultaneous alteration of de novo and salvage pathway to the deoxynucleoside triphosphate pool by (E)-2'-deoxy-(fluoromethylene)cytidine (FMdC) and zidovudine (AZT) results in increased radiosensitivity in vitro. | Acta oncologica (Stockholm, Sweden) 20070101 |
Differential regulation of Smac/DIABLO and Hsp-70 during brain maturation. | Neuromolecular medicine 20070101 |
Analysis of double stranded DNA-dependent activities of Deinococcus radiodurans RecA protein. | Journal of microbiology (Seoul, Korea) 20061001 |
Positive inotropic effects of low dATP/ATP ratios on mechanics and kinetics of porcine cardiac muscle. | Biophysical journal 20060915 |
Differential regulation of the intrinsic pathway of apoptosis in brain and liver during ageing. | FEBS letters 20060626 |
An efficiently extended class of unnatural base pairs. | Journal of the American Chemical Society 20060531 |
Deoxy-adenosine-monophosphate (dAMP) di-n-butylester induces apoptosis by increasing the dATP level in HL-60 cells. | Cancer letters 20060428 |
Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex. | The Journal of biological chemistry 20060217 |
Differential sensitivity of the cystic fibrosis (CF)-associated mutants G551D and G1349D to potentiators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel. | The Journal of biological chemistry 20060127 |
Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway. | BMC cancer 20060101 |
[Association between high activity of DNA polymerase iota and the development of human uveal melanoma]. | Genetika 20060101 |
T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking. | BMC medical genetics 20060101 |
Radiosensitizers in cervical cancer. Cisplatin and beyond. | Radiation oncology (London, England) 20060101 |
TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells. | BMC cancer 20060101 |
Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress. | BMC cancer 20060101 |
Substrate property and incorporation accuracy of various dATP analogs during enzymatic polymerization using thermostable DNA polymerases. | Nucleic acids symposium series (2004) 20060101 |
Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity. | Current medicinal chemistry 20060101 |
Developmental shift in the apostat: comparison of neurones and astrocytes. | FEBS letters 20051107 |
Four-color multiplex reverse transcription polymerase chain reaction--overcoming its limitations. | Analytical biochemistry 20050901 |
Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension. | Chemical research in toxicology 20050901 |
Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues. | International journal of hematology 20050601 |
Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools. | Biochemistry 20050503 |
A novel ADP/ATP transporter in the mitosome of the microaerophilic human parasite Entamoeba histolytica. | Current biology : CB 20050426 |
Caspase-3 can be pseudo-activated by a Ca2+-dependent proteolysis at a non-canonical site. | FEBS letters 20050425 |
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. | Journal of the American Chemical Society 20050413 |
A nucleotide binding site in caspase-9 regulates apoptosome activation. | Biochemistry 20050405 |
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. | Biochemistry 20050308 |
Kinetic studies of DNA cleavage reactions catalyzed by an ATP-dependent deoxyribonuclease on a 27-MHz quartz-crystal microbalance. | Biochemistry 20050222 |
Biosynthesis reaction mechanism and kinetics of deoxynucleoside triphosphates, dATP and dGTP. | Biotechnology and bioengineering 20050220 |
Role of base stacking and sequence context in the inhibition of yeast DNA polymerase eta by pyrene nucleotide. | Biochemistry 20041123 |
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. | Biochemistry 20041102 |
Effective metabolism and long intracellular half life of the anti-hepatitis B agent adefovir in hepatic cells. | Biochemical pharmacology 20041101 |
Expression of NALP1 in cerebellar granule neurons stimulates apoptosis. | Cellular signalling 20040901 |
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. | The EMBO journal 20040901 |
Cardiac length dependence of force and force redevelopment kinetics with altered cross-bridge cycling. | Biophysical journal 20040901 |
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. | Nature biotechnology 20040601 |
Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA. | Arthritis and rheumatism 20040501 |
Increased expression of Apaf-1 and procaspase-3 and the functionality of intrinsic apoptosis apparatus in non-small cell lung carcinoma. | Biological chemistry 20040201 |
Evaluating the contribution of base stacking during translesion DNA replication. | Biochemistry 20040120 |
[Physiological and biochemical analysis of the transformants of aerobic methylobacteria expressing the dcm A gene of dichloromethane dehydrogenase]. | Mikrobiologiia 20040101 |
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. | BMC biology 20040101 |
Melatonin promoted chemotaxins expression in lung epithelial cell stimulated with TNF-alpha. | Respiratory research 20040101 |
Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. | Biochemistry 20031230 |
Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia. | Leukemia research 20031201 |
Impaired germinal center maturation in adenosine deaminase deficiency. | Journal of immunology (Baltimore, Md. : 1950) 20031115 |
Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA. | The Journal of biological chemistry 20031107 |
Inhibition of human immunodeficiency virus reverse transcriptase by synadenol triphosphate and its E-isomer. | Journal of medicinal chemistry 20031023 |
Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells. | Cancer research 20031015 |
Suppressive effect of viscous dietary fiber on elevations of uric acid in serum and urine induced by dietary RNA in rats is associated with strength of viscosity. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20031001 |
Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors. | Journal of molecular biology 20030627 |
Selective labeling and detection of specific RNAs in an RNA mixture. | Analytical biochemistry 20030401 |
Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. | Nucleosides, nucleotides & nucleic acids 20030301 |
Conformational properties of nucleotide-based template-competitive HIV-1 reverse transcriptase inhibitors: analysis of enzyme binding modes. | Nucleosides, nucleotides & nucleic acids 20030301 |
Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences. | Biochemistry 20030218 |
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. | Biochemistry 20030218 |
Portrait of a killer: the mitochondrial apoptosome emerges from the shadows. | Molecular interventions 20030201 |
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. | Science (New York, N.Y.) 20030110 |
Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential. | Structure (London, England : 1993) 20030101 |
Neurological phenotype and synaptic function in mice lacking the CaV1.3 alpha subunit of neuronal L-type voltage-dependent Ca2+ channels. | Neuroscience 20030101 |
Ability of adenosine-2'(3')-deoxy-3'(2')-triphosphates and related analogues to replace ATP as phosphate donor for all human and Drosphila melanogaster deoxyribonucleoside kinases. | Nucleosides, nucleotides & nucleic acids 20030101 |
Synthesis and recognition by DNA polymerases of a reactive nucleoside for DNA diversification. | Nucleosides, nucleotides & nucleic acids 20030101 |
Repeated cocaine administration differentially affects NMDA receptor subunit (NR1, NR2A-C) mRNAs in rat brain. | Synapse (New York, N.Y.) 20021201 |
Excess dNTPs minimize RNA hydrolysis during reverse transcription. | BioTechniques 20021101 |
Enhancement of nucleoside cytotoxicity through nucleotide prodrugs. | Journal of medicinal chemistry 20020926 |
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta. | Biochemistry 20020917 |
Purine and pyrimidine (P2) receptors as drug targets. | Journal of medicinal chemistry 20020912 |
Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation. | The Journal of clinical investigation 20020801 |
Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777. | International immunopharmacology 20020601 |
Nucleoside triphosphate pentose ring impact on CFTR gating and hydrolysis. | FEBS letters 20020508 |
Expression and functional analysis of an inhibitor of apoptosis protein from Trichoplusia ni. | Biochemical and biophysical research communications 20020503 |
Identification of a domain conferring nucleotide binding to the N-acetyl-d-glucosamine 2-epimerase (Renin binding protein). | Journal of biochemistry 20020401 |
Template-competitive inhibitors of HIV-1 reverse transcriptase: design, synthesis and inhibitory activity. | Bioorganic & medicinal chemistry 20020301 |
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside. | Cell death and differentiation 20020201 |
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release. | Blood 20020115 |
2-Amino-7-deazaadenine forms stable base pairs with cytosine and thymine. | Bioorganic & medicinal chemistry letters 20020107 |
Immunoreactive localisation of P2Y1 receptors within the rat and human nodose ganglia and rat brainstem: comparison with [alpha 33P]deoxyadenosine 5'-triphosphate autoradiography. | Neuroscience 20020101 |
A quantitative method to measure telomerase activity by bioluminescence connected with telomeric repeat amplification protocol. | Analytical biochemistry 20011215 |
Hydroxyurea does not enhance the anti-HIV activity of low-dose tenofovir disoproxil fumarate. | Journal of acquired immune deficiency syndromes (1999) 20011201 |
Effects of nucleotides on N-acetyl-d-glucosamine 2-epimerases (renin-binding proteins): comparative biochemical studies. | Journal of biochemistry 20011201 |
Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome. | The Journal of biological chemistry 20011109 |
Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. | RNA (New York, N.Y.) 20011101 |
Identification of nucleotides with identical fluorescent labels based on fluorescence polarization in surfactant solutions. | Analytical chemistry 20010915 |
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. | Blood 20010901 |
Structural basis for allosteric substrate specificity regulation in anaerobic ribonucleotide reductases. | Structure (London, England : 1993) 20010801 |
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling. | The Journal of clinical investigation 20010701 |
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. | Biochemistry 20010605 |
Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen. | Journal of molecular biology 20010601 |
Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010415 |
Screening of an enterovirus specific RT-PCR ELISA method for the quantification of enterovirus genomes in human body fluids by means of a three-level experimental design. | Journal of pharmaceutical and biomedical analysis 20010401 |
Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex. | Cell death and differentiation 20010401 |
Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex. | Biochemistry 20010313 |
Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. | The EMBO journal 20010301 |
Ultraviolet crosslinking of DNA-protein complexes via 8-azidoadenine. | Methods in molecular biology (Clifton, N.J.) 20010101 |
In vitro and in vivo inhibition of telomerase activity from Chinese hamster V79 cells. | Indian journal of biochemistry & biophysics 20010101 |
Pharmacological characterization of the human P2Y11 receptor. | British journal of pharmacology 19991101 |
Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein. | The Journal of general virology 19990301 |
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. | Proceedings of the National Academy of Sciences of the United States of America 19981110 |
Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine. | The Journal of biological chemistry 19981016 |
Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity. | Molecular pharmacology 19980801 |
Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay. | Biochemistry 19970204 |
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines. | Molecular pharmacology 19960801 |
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates. | The Journal of biological chemistry 19951006 |
Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs. | Antiviral research 19931201 |
RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria. | Journal of virology 19930201 |
HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587. | Biochemical pharmacology 19920317 |
MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. | Nature 19920116 |
Inhibition of HIV reverse transcriptase by 2',3'-dideoxynucleoside triphosphates. | Biochemical pharmacology 19871215 |
Aggregate formation in solutions of deoxynucleoside triphosphates, dATP + dTTP. | Archives of biochemistry and biophysics 19720601 |
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