200,000+ products from a single source!
sales@angenechem.com
192322-50-2 | 1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
CAS No: 192322-50-2 Catalog No: AG002FTZ MDL No:
Product Description
Catalog Number:
AG002FTZ
Chemical Name:
1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
CAS Number:
192322-50-2
Molecular Formula:
C26H30ClN5O2S
Molecular Weight:
512.0667
IUPAC Name:
N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide;hydrochloride
InChI:
InChI=1S/C26H29N5O2S.ClH/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24;/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31);1H
InChI Key:
DIQDKUNCSVFGHH-UHFFFAOYSA-N
SMILES:
Nc1nc(NC[C@@H]2CC[C@H](CC2)CNS(=O)(=O)c2cccc3c2cccc3)nc2c1cccc2.Cl
UNII:
45B73P82A3
Properties
Complexity:
751
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
511.181g/mol
Formal Charge:
0
Heavy Atom Count:
35
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
512.069g/mol
Monoisotopic Mass:
511.181g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
118A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line. | Molecular cancer research : MCR 20100401 |
| Neuropeptide Y-induced enhancement of the evoked release of newly synthesized dopamine in rat striatum: mediation by Y2 receptors. | Neuropharmacology 20070501 |
| Preparation of fluorescent nonpeptidic neuropeptide Y receptor ligands: analogues of the quinazoline-type anti-obesity Y5 antagonist CGP 71683A. | Archiv der Pharmazie 20031201 |
| Development and characterization of a highly selective neuropeptide Y Y5 receptor agonist radioligand: [125I][hPP1-17, Ala31, Aib32]NPY. | British journal of pharmacology 20030801 |
| Reduced food intake in response to CGP 71683A may be due to mechanisms other than NPY Y5 receptor blockade. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.