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CAS No: 1916-59-2 Catalog No: AG00387C MDL No:
Title | Journal |
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Enhancement of cytotoxic and pro-apoptotic effects of 2-aminophenoxazine-3-one on the rat hepatocellular carcinoma cell line dRLh-84, the human hepatocellular carcinoma cell line HepG2, and the rat normal hepatocellular cell line RLN-10 in combination with 2-deoxy-D-glucose. | Oncology reports 20120201 |
Involvement of endoplasmic reticulum stress-mediated CHOP (GADD153) induction in the cytotoxicity of 2-aminophenoxazine-3-one in cancer cells. | International journal of oncology 20111001 |
2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
Rapid decrease of intracellular pH associated with inhibition of Na+/H+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one. | Oncology reports 20110201 |
Selectively induced apoptosis in human neutrophils in the presence of oxidative phenoxazines, 2-amino-4,4α-dihydryo-4α-7H-phenoxazine-3-one and 2-aminophenoxazine-3-one, preceded by decrease of intracellular pH, depolarization of the mitochondria, and inhibition of superoxide generation. | Journal of pharmacological sciences 20110101 |
Structure-activity relationship of benzoxazinones and related compounds with respect to the growth inhibition and alpha-amylase activity in cress seedlings. | Journal of plant physiology 20101015 |
A copper-containing oxidase catalyzes C-nitrosation in nitrosobenzamide biosynthesis. | Nature chemical biology 20100901 |
Structure and antibacterial activity of the silver(I) complex of 2-aminophenoxazine-3-one. | Metallomics : integrated biometal science 20100801 |
Anticancer activity of phenoxazines produced by bovine erythrocytes on colon cancer cells. | Oncology reports 20100601 |
2-Aminophenoxazine-3-one induces cellular apoptosis by causing rapid intracellular acidification and generating reactive oxygen species in human lung adenocarcinoma cells. | International journal of oncology 20100301 |
In vitro antibacterial activity of Phx-3 against Helicobacter pylori. | Biological & pharmaceutical bulletin 20100101 |
Inhibitory effects of 2-amino-3H-phenoxazin-3-one on the melanogenesis of murine B16 melanoma cell line. | Bioscience, biotechnology, and biochemistry 20100101 |
2-aminophenoxazine-3-one prevents pulmonary metastasis of mouse B16 melanoma cells in mice. | Journal of pharmacological sciences 20100101 |
Phenoxazine derivatives suppress the infections caused by herpes simplex virus type-1 and herpes simplex virus type-2 intravaginally inoculated into mice. | Journal of pharmacological sciences 20100101 |
Anticancer effects of phenoxazine derivatives revealed by inhibition of cell growth and viability, disregulation of cell cycle, and apoptosis induction in HTLV-1-positive leukemia cells. | Journal of pharmacological sciences 20090501 |
Mitochondrial depolarization and apoptosis associated with sustained activation of c-jun-N-terminal kinasein the human multiple myeloma cell line U266 induced by 2-aminophenoxazine-3-one. | Molecular medicine reports 20090101 |
Anti-inflammatory and immunomodulatory properties of 2-amino-3H-phenoxazin-3-one. | Biological & pharmaceutical bulletin 20081001 |
Suppression of the proliferation of cancer cell lines, KB-3-1 and K562 cells preceded by a decrease in intracellular pH caused by phenoxazine derivatives. | Oncology reports 20080501 |
Phenoxazine derivatives inactivate human cytomegalovirus, herpes simplex virus-1, and herpes simplex virus-2 in vitro. | Journal of pharmacological sciences 20080301 |
Synthesis and testing of chromogenic phenoxazinone substrates for beta-alanyl aminopeptidase. | Organic & biomolecular chemistry 20080221 |
Capillary electrophoresis enzyme immunoassay for alpha-fetoprotein and thyroxine in human serum with electrochemical detection. | Journal of separation science 20080201 |
Apoptosis induction preceded by mitochondrial depolarization in multiple myeloma cell line U266 by 2-aminophenoxazine-3-one. | Biological & pharmaceutical bulletin 20080101 |
Investigation of the interaction between ssDNA and 2-aminophenoxazine-3-one and development of an electrochemical DNA biosensor. | Oligonucleotides 20080101 |
CE-based simultaneous liquid-phase noncompetitive enzyme immunoassay for three tumor markers in human serum using electrochemical detection. | Electrophoresis 20071201 |
A tetracopper(II)-tetraradical cuboidal core and its reactivity as a functional model of phenoxazinone synthase. | Inorganic chemistry 20071112 |
Silica-immobilized enzymes for multi-step synthesis in microfluidic devices. | Biotechnology and bioengineering 20071015 |
Interactions of Bacillus mojavensis and Fusarium verticillioides with a benzoxazolinone (BOA) and its transformation product, APO. | Journal of chemical ecology 20071001 |
Caspase-independent cell death revealed in human gastric cancer cell lines, MKN45 and KATO III treated with phenoxazine derivatives. | Oncology reports 20070201 |
Phenoxazine derivatives 2-amino-4,4alpha-dihydro-4alpha-phenoxazine-3-one and 2-aminophenoxazine-3-one-induced apoptosis through a caspase-independent mechanism in human neuroblastoma cell line NB-1 cells. | Biological & pharmaceutical bulletin 20070201 |
Phenoxazine derivatives induce caspase-independent cell death in human glioblastoma cell lines, A-172 and U-251 MG. | Oncology reports 20070101 |
2-aminophenoxazine-3-one suppresses the growth of mouse malignant melanoma B16 cells transplanted into C57BL/6Cr Slc mice. | Biological & pharmaceutical bulletin 20061101 |
Actinomycins with altered threonine units in the beta-peptidolactone. | Journal of natural products 20060801 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Anticancer effects of phenoxazine derivatives combined with tumor necrosis factor-related apoptosis-inducing ligand on pancreatic cancer cell lines, KLM-1 and MIA-PaCa-2. | Oncology reports 20060401 |
Effects of some benzoxazinoids on in vitro growth of Cephalosporium gramineum and other fungi pathogenic to cereals and on Cephalosporium stripe of winter wheat. | Journal of agricultural and food chemistry 20060222 |
Structure-activity relationship (SAR) studies of benzoxazinones, their degradation products, and analogues. Phytotoxicity on problematic weeds Avena fatua L. and Lolium rigidum Gaud. | Journal of agricultural and food chemistry 20060222 |
Fate of benzoxazinone allelochemicals in soil after incorporation of wheat and rye sprouts. | Journal of agricultural and food chemistry 20060222 |
Transformation of benzoxazinones and derivatives and microbial activity in the test environment of soil ecotoxicological tests on Poecilus cupreus and Folsomia candida. | Journal of agricultural and food chemistry 20060222 |
QSAR models for Daphnia magna toxicity prediction of benzoxazinone allelochemicals and their transformation products. | Journal of agricultural and food chemistry 20060222 |
New aminophenoxazinones from a marine Halomonas sp.: fermentation, structure elucidation, and biological activity. | The Journal of antibiotics 20060201 |
Chlamydia pneumoniae growth inhibition in human monocytic THP-1 cells and human epithelial HEp-2 cells by a novel phenoxazine derivative. | Journal of medical microbiology 20051201 |
Transformation products of 2-benzoxazolinone (BOA) in soil. | Chemosphere 20050901 |
Differentiation and apoptosis in human malignant melanoma G-361 cells induced by 2-aminophenoxazine-3-one. | Oncology reports 20050701 |
2-amino-phenoxazine-3-one attenuates glucose-induced augmentation of embryonic form of myosin heavy chain, endothelin-1 and plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. | Biological & pharmaceutical bulletin 20050501 |
Biotransformation of 2-benzoxazolinone to 2-amino-(3H)-phenoxazin-3-one and 2-acetylamino-(3H)-phenoxazin-3-one in soil. | Journal of chemical ecology 20050501 |
Structure-Activity Relationships (SAR) studies of benzoxazinones, their degradation products and analogues. phytotoxicity on standard target species (STS). | Journal of agricultural and food chemistry 20050209 |
Degradation studies on benzoxazinoids. Soil degradation dynamics of (2R)-2-O-beta-D-glucopyranosyl-4-hydroxy-(2H)- 1,4-benzoxazin-3(4H)-one (DIBOA-Glc) and its degradation products, phytotoxic allelochemicals from Gramineae. | Journal of agricultural and food chemistry 20050209 |
Phenoxazine compounds produced by the reactions with bovine hemoglobin show antimicrobial activity against non-tuberculosis mycobacteria. | The Tohoku journal of experimental medicine 20040501 |
Kinetics and mechanism of the ferroxime(II)-catalysed biomimetic oxidation of 2-aminophenol by dioxygen. A functional phenoxazinone synthase model. | Dalton transactions (Cambridge, England : 2003) 20040407 |
Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity. | Journal of medicinal chemistry 20021121 |
Hydroxylated 2-amino-3H-phenoxazin-3-one derivatives as products of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) biotransformation by Chaetosphaeria sp., an endophytic fungus from Aphelandra tetragona. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
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