200,000+ products from a single source!
sales@angenechem.com
19036-43-2 | Propanoic acid, 3-amino-2,2-dimethyl-
CAS No: 19036-43-2 Catalog No: AG002EIL MDL No:MFCD09055365
Product Description
Catalog Number:
AG002EIL
Chemical Name:
Propanoic acid, 3-amino-2,2-dimethyl-
CAS Number:
19036-43-2
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD09055365
IUPAC Name:
3-amino-2,2-dimethylpropanoic acid
InChI:
InChI=1S/C5H11NO2/c1-5(2,3-6)4(7)8/h3,6H2,1-2H3,(H,7,8)
InChI Key:
DGNHGRLDBKAPEH-UHFFFAOYSA-N
SMILES:
NCC(C(=O)O)(C)C
UNII:
GN6Q6N22NJ
NSC Number:
32047
Properties
Complexity:
98.6
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
117.079g/mol
Formal Charge:
0
Heavy Atom Count:
8
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
117.148g/mol
Monoisotopic Mass:
117.079g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.6
Literature
| Title | Journal |
|---|---|
| Amino acid transport system A is involved in inflammatory nociception in rats. | Brain research 20120417 |
| System A activity and vascular function in the placental-specific Igf2 knockout mouse. | Placenta 20111101 |
| Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress. | Placenta 20101101 |
| Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons. | Neuroscience 20091215 |
| Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes. | American journal of physiology. Endocrinology and metabolism 20090901 |
| Seasonal variation in glucose and neutral amino acid uptake in the estuarine crab Neohelice granulata. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20090701 |
| System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate. | Cerebral cortex (New York, N.Y. : 1991) 20090501 |
| Temperature dependence of rotational disorder in a non-standard amino acid from X-ray crystallography and molecular dynamics simulation. | Physical chemistry chemical physics : PCCP 20090421 |
| Role of 1alpha,25(OH)2 vitamin D3 on alpha-[1-(14)C]MeAIB accumulation in immature rat testis. | Steroids 20090201 |
| The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane. | The Journal of physiology 20090101 |
| Glutamine uptake contributes to central sensitization in the medullary dorsal horn. | Neuroreport 20080716 |
| Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells. | Journal of the American Society of Nephrology : JASN 20070501 |
| Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy. | Neurobiology of disease 20070201 |
| Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. | The Journal of physiology 20061101 |
| Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport. | European journal of nuclear medicine and molecular imaging 20061001 |
| Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816 |
| N,N-dimethyl-beta-alanine as an inexpensive and efficient ligand for palladium-catalyzed Heck reaction. | Organic letters 20060608 |
| Preparation and tumor affinity testing of the radioiodinated tetrahydroisoquinoline derivative [123I]TIC(OH) for targeting prostate cancer. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20060501 |
| Tyrosine transport in fibroblasts from healthy volunteers and patients with schizophrenia. | Neuroscience letters 20060130 |
| Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cells. | Biochimie 20060101 |
| IGF regulation of neutral amino acid transport in the BeWo choriocarcinoma cell line (b30 clone): evidence for MAP kinase-dependent and MAP kinase-independent mechanisms. | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20060101 |
| Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition. | Neuroscience letters 20050418 |
| Effect of hyper or hypo-osmotic conditions on neutral amino acid uptake and oxidation in tissues of the crab Chasmagnathus granulata. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050401 |
| Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action. | Molecular psychiatry 20050301 |
| Hormonal regulation of glucose and system A amino acid transport in first trimester placental villous fragments. | American journal of physiology. Regulatory, integrative and comparative physiology 20050301 |
| System beta and system A amino acid transporters in the feline endotheliochorial placenta. | American journal of physiology. Regulatory, integrative and comparative physiology 20041201 |
| N-(methylamino)isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells. | Biochemical pharmacology 20040715 |
| Involvement of K+ channels and calcium-dependent pathways in the action of T3 on amino acid accumulation and membrane potential in Sertoli cells of immature rat testis. | Life sciences 20040123 |
| Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways. | The Journal of biological chemistry 20031107 |
| Distribution and pharmacology of alanine-serine-cysteine transporter 1 (asc-1) in rodent brain. | The European journal of neuroscience 20031001 |
| Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture. | FEBS letters 20030731 |
| Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. | Journal of neurochemistry 20030401 |
| Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments. | The Journal of clinical endocrinology and metabolism 20030301 |
| Uptake of [N-methyl-11C]alpha-methylaminoisobutyric acid in untreated head and neck cancer studied by PET. | European journal of nuclear medicine and molecular imaging 20030101 |
| Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells. | European journal of pharmacology 20030101 |
| Transport of 14C-gamma-aminobutyric acid into brain, cerebrospinal fluid and choroid plexus in neonatal and adult rats. | Brain research. Developmental brain research 20021215 |
| The IGF-II-deficient placenta: aspects of its function. | Trends in endocrinology and metabolism: TEM 20021201 |
| Amino acid uptake in the skeletal muscle measured using [11C]methylaminoisobutyrate (MEAIB) and PET. | European journal of nuclear medicine and molecular imaging 20021101 |
| Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells. | American journal of obstetrics and gynecology 20020701 |
| ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline. | Molecular pharmacology 20020601 |
| ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane. | Archives of biochemistry and biophysics 20020415 |
| Na+-independent transporters, LAT-2 and b0,+, exchange L-DOPA with neutral and basic amino acids in two clonal renal cell lines. | The Journal of membrane biology 20020315 |
| Physiological importance of system A-mediated amino acid transport to rat fetal development. | American journal of physiology. Cell physiology 20020101 |
| Glutamine uptake by neurons: interaction of protons with system a transporters. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101 |
| A chronic low dose infusion of insulin-like growth factor I alters placental function but does not affect fetal growth. | Reproduction, fertility, and development 20020101 |
| Regulation of glutamate transport and transport proteins in a placental cell line. | American journal of physiology. Cell physiology 20010901 |
| Effect of 3,5,3'-triiodo-L-thyronine on amino acid accumulation and membrane potential in Sertoli cells of the rat testis. | Life sciences 20010713 |
| Biodistribution of [11C] methylaminoisobutyric acid, a tracer for PET studies on system A amino acid transport in vivo. | European journal of nuclear medicine 20010701 |
| Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport. | The Journal of biological chemistry 20010629 |
| Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. | The Journal of biological chemistry 20010518 |
| Osmotic regulation of ATA2 mRNA expression and amino acid transport System A activity. | Biochemical and biophysical research communications 20010427 |
| Electrogenic Na(+)-dependent L-alanine transport in the lizard duodenum. Involvement of systems A and ASC. | American journal of physiology. Regulatory, integrative and comparative physiology 20010301 |
| Insulin-like growth factor-I stimulates amino acid transport in a glutamine-deprived human neuroblastoma cell line. | Biochimica et biophysica acta 20010216 |
| Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A. | Biochimica et biophysica acta 20010209 |
| Characterization of 3-[(123)I]iodo-L-alpha-methyl tyrosine transport in astrocytes of neonatal rats. | Journal of neurochemistry 20010101 |
| The effect of heat shock on amino acid transport and cell volume in 3T3 cells. | Amino acids 20010101 |
| Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A. | Biochimica et biophysica acta 20000731 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.