200,000+ products from a single source!
sales@angenechem.com
188116-08-7 | 2H-Imidazol-2-one, 1-(4-chlorophenyl)-1,5-dihydro-4-(1-piperidinyl)-
CAS No: 188116-08-7 Catalog No: AG002GP8 MDL No:
Product Description
Catalog Number:
AG002GP8
Chemical Name:
2H-Imidazol-2-one, 1-(4-chlorophenyl)-1,5-dihydro-4-(1-piperidinyl)-
CAS Number:
188116-08-7
Molecular Formula:
C14H16ClN3O
Molecular Weight:
277.7493
IUPAC Name:
3-(4-chlorophenyl)-5-piperidin-1-yl-4H-imidazol-2-one
InChI:
InChI=1S/C14H16ClN3O/c15-11-4-6-12(7-5-11)18-10-13(16-14(18)19)17-8-2-1-3-9-17/h4-7H,1-3,8-10H2
InChI Key:
YGXIELIREXEJQN-UHFFFAOYSA-N
SMILES:
O=C1N=C(CN1c1ccc(cc1)Cl)N1CCCCC1
UNII:
BKP2A5554F
Properties
Complexity:
371
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
277.098g/mol
Formal Charge:
0
Heavy Atom Count:
19
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
277.752g/mol
Monoisotopic Mass:
277.098g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
35.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.4
Literature
| Title | Journal |
|---|---|
| Modifications of antiepileptic drugs for improved tolerability and efficacy. | Perspectives in medicinal chemistry 20080101 |
| The novel anxiolytic ELB139 displays selectivity to recombinant GABA(A) receptors different from diazepam. | Neuropharmacology 20070301 |
| ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study. | Pharmacology, biochemistry, and behavior 20070101 |
| Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors. | Journal of medicinal chemistry 20060323 |
| GABA-A receptors: a viable target for novel anxiolytics? | Current opinion in pharmacology 20060201 |
| Targeting neurological receptors. | IDrugs : the investigational drugs journal 20051201 |
| Characterization in rats of the anxiolytic potential of ELB139 [1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a new agonist at the benzodiazepine binding site of the GABAA receptor. | The Journal of pharmacology and experimental therapeutics 20050801 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.