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CAS No: 18771-50-1 Catalog No: AG0038WM MDL No:
Title | Journal |
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Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo. | International journal of cancer 20120701 |
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. | Blood 20120202 |
Tetrahydrouridine inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels. | PloS one 20120101 |
Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications. | The Journal of toxicological sciences 20110801 |
Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice. | Cancer chemotherapy and pharmacology 20110201 |
An APCI LC-MS/MS method for routine determination of capecitabine and its metabolites in human plasma. | Journal of mass spectrometry : JMS 20100601 |
Stability of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in combination. | AAPS PharmSciTech 20100301 |
Is the resistance of gemcitabine for pancreatic cancer settled only by overexpression of deoxycytidine kinase? | Oncology reports 20100201 |
Synthesis of deoxytetrahydrouridine. | The Journal of organic chemistry 20090306 |
Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice. | Cancer chemotherapy and pharmacology 20080801 |
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU). | Cancer chemotherapy and pharmacology 20080701 |
Optimized blood sampling with cytidine deaminase inhibitor for improved analysis of capecitabine metabolites. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080701 |
Modulation of gemcitabine (2',2'-difluoro-2'-deoxycytidine) pharmacokinetics, metabolism, and bioavailability in mice by 3,4,5,6-tetrahydrouridine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080601 |
Quantitative determination of the cytidine deaminase inhibitor tetrahydrouridine (THU) in mouse plasma by liquid chromatography/electrospray ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse. | Biochemistry 20060627 |
Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide. | Chemical research in toxicology 20060101 |
Structure of human cytidine deaminase bound to a potent inhibitor. | Journal of medicinal chemistry 20050210 |
Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth. | Molecular microbiology 20031101 |
Epimer interconversion, isomerization, and hydrolysis of tetrahydrouridine: implications for cytidine deaminase inhibition. | Journal of pharmaceutical sciences 20031001 |
Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine. | Biochemical pharmacology 20021115 |
Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice. | International journal of radiation oncology, biology, physics 20011101 |
Regulatory effects of deoxyribonucleosides on the activity of 5-methoxymethyl-2'-deoxycytidine: modulation of antiherpes activity by deoxyguanosine and tetrahydrodeoxyuridine. | Antiviral research 19910501 |
Antiherpes virus activity and effect on deoxyribonucleoside triphosphate pools of (E)-5-(2-bromovinyl)-2'-deoxycytidine in combination with deaminase inhibitors. | Antiviral research 19900301 |
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