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Home > Pyridines > 182485-36-5

182485-36-5

182485-36-5 | Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-

CAS No: 182485-36-5 Catalog No: AG0023WS MDL No:MFCD01074806

Product Description

Catalog Number:
AG0023WS
Chemical Name:
Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-
CAS Number:
182485-36-5
Molecular Formula:
C6H12NO2P
Molecular Weight:
161.1387
MDL Number:
MFCD01074806
IUPAC Name:
methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
InChI:
InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
InChI Key:
MFUKVPOVVKKLRQ-UHFFFAOYSA-N
SMILES:
CP(=O)(C1=CCNCC1)O
UNII:
TR7I0800L2

Properties

Complexity:
200  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
161.061g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
161.141g/mol
Monoisotopic Mass:
161.061g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
49.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.5  

Literature

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Dopamine and serotonin modulate human GABAρ1 receptors expressed in Xenopus laevis oocytes. ACS chemical neuroscience 20120215
Nonlinear interactions between excitatory and inhibitory retinal synapses control visual output. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Potentiating action of propofol at GABAA receptors of retinal bipolar cells. Investigative ophthalmology & visual science 20110401
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Postnatal switch from synaptic to extrasynaptic transmission between interneurons and NG2 cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100519
Selective induction of astrocytic gliosis generates deficits in neuronal inhibition. Nature neuroscience 20100501
GABAC receptors are functionally expressed in the intermediate zone and regulate radial migration in the embryonic mouse neocortex. Neuroscience 20100428
GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113
Antagonists of ionotropic gamma-aminobutyric acid receptors impair the NiCl2-mediated stimulation of the electroretinogram b-wave amplitude from the isolated superfused vertebrate retina. Acta ophthalmologica 20091101
Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cells. Molecular and cellular neurosciences 20090901
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Development of presynaptic inhibition onto retinal bipolar cell axon terminals is subclass-specific. Journal of neurophysiology 20080701
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Relative impact of residues at the intracellular and extracellular ends of the human GABAC rho1 receptor M2 domain on picrotoxinin activity. European journal of pharmacology 20080202
Inhibitory feedback shapes bipolar cell responses in the rabbit retina. Journal of neurophysiology 20071201
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The synaptic mechanism of direction selectivity in distal processes of starburst amacrine cells. Neuron 20060921
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Melatonin decreases calcium levels in retinotectal axons of Xenopus laevis by indirect activation of group III metabotropic glutamate receptors. Brain research 20050816
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Opposing roles for GABAA and GABAC receptors in short-term memory formation in young chicks. Neuroscience 20050101
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. Neuron 20041028
The spinal GABAergic system is a strong modulator of burst frequency in the lamprey locomotor network. Journal of neurophysiology 20041001
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Timing of quantal release from the retinal bipolar terminal is regulated by a feedback circuit. Neuron 20030410
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