200,000+ products from a single source!
sales@angenechem.com
179386-43-7 | 4H-Imidazo[4,5,1-ij]quinolin-2(1H)-one, 5,6-dihydro-5-(methylamino)-, (5R)-
CAS No: 179386-43-7 Catalog No: AG0026YS MDL No:
Product Description
Catalog Number:
AG0026YS
Chemical Name:
4H-Imidazo[4,5,1-ij]quinolin-2(1H)-one, 5,6-dihydro-5-(methylamino)-, (5R)-
CAS Number:
179386-43-7
Molecular Formula:
C11H13N3O
Molecular Weight:
203.2404
IUPAC Name:
(10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
InChI:
InChI=1S/C11H13N3O/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9/h2-4,8,12H,5-6H2,1H3,(H,13,15)/t8-/m1/s1
InChI Key:
RKZSNTNMEFVBDT-MRVPVSSYSA-N
SMILES:
CN[C@@H]1Cc2cccc3c2n(C1)c(=O)[nH]3
UNII:
3E93IV1U45
Properties
Complexity:
281
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
203.106g/mol
Formal Charge:
0
Heavy Atom Count:
15
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
203.245g/mol
Monoisotopic Mass:
203.106g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
44.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.4
Literature
| Title | Journal |
|---|---|
| Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists. | Psychopharmacology 20120101 |
| Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. | The Journal of pharmacology and experimental therapeutics 20100801 |
| The effects of the dopamine D2 agonist sumanirole on prepulse inhibition in rats. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100601 |
| The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys. | Psychopharmacology 20090901 |
| The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats. | Psychopharmacology 20090401 |
| Motor sequence learning in primate: role of the D2 receptor in movement chunking during consolidation. | Behavioural brain research 20090302 |
| Asymmetric synthesis of tetrahydroquinolin-3-ols via CoCl2-catalyzed reductive cyclization of nitro cyclic sulfites with NaBH4. | Organic letters 20090219 |
| Sumanirole versus placebo or ropinirole for the adjunctive treatment of patients with advanced Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20070315 |
| A comparison of sumanirole versus placebo or ropinirole for the treatment of patients with early Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20070315 |
| Efficacy and tolerability of sumanirole in restless legs syndrome: a phase II, randomized, double-blind, placebo-controlled, dose-response study. | Sleep medicine 20070301 |
| The effects of a selective dopamine D2 receptor agonist on behavioral and pathological outcome in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys. | The Journal of pharmacology and experimental therapeutics 20050901 |
| Sumanirole, a highly dopamine D2-selective receptor agonist: in vitro and in vivo pharmacological characterization and efficacy in animal models of Parkinson's disease. | The Journal of pharmacology and experimental therapeutics 20050901 |
| Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction. | Journal of medicinal chemistry 20040715 |
| Sumanirole Pharmacia. | Current opinion in investigational drugs (London, England : 2000) 20030101 |
| Synthesis and biological activities of (R)-5,6-dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and its metabolites. | Journal of medicinal chemistry 19970227 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.