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Home > Pyridines > 179120-92-4
179120-92-4 | Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-
CAS No: 179120-92-4 Catalog No: AG0026TE MDL No:
Product Description
Catalog Number:
AG0026TE
Chemical Name:
Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-
CAS Number:
179120-92-4
Molecular Formula:
C12H14N2
Molecular Weight:
186.2530
IUPAC Name:
3-ethynyl-5-[(2S)-1-methylpyrrolidin-2-yl]pyridine
InChI:
InChI=1S/C12H14N2/c1-3-10-7-11(9-13-8-10)12-5-4-6-14(12)2/h1,7-9,12H,4-6H2,2H3/t12-/m0/s1
InChI Key:
NUPUDYKEEJNZRG-LBPRGKRZSA-N
SMILES:
C#Cc1cncc(c1)[C@@H]1CCCN1C
UNII:
RJ9V9V09VM
Properties
Complexity:
240
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
186.116g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
186.258g/mol
Monoisotopic Mass:
186.116g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
16.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4
Literature
| Title | Journal |
|---|---|
| Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications. | The Journal of organic chemistry 20110805 |
| Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist. | Brain research 20081009 |
| Expedient five-step synthesis of SIB-1508Y from natural nicotine. | The Journal of organic chemistry 20061027 |
| Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease. | Neurology 20060214 |
| Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. | Journal of medicinal chemistry 20050728 |
| Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501 |
| Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine. | The Journal of pharmacology and experimental therapeutics 20000901 |
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