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1783-96-6

1783-96-6 | H-D-Asp-OH

CAS No: 1783-96-6 Catalog No: AG0025XN MDL No:MFCD00063081

Product Description

Catalog Number:
AG0025XN
Chemical Name:
H-D-Asp-OH
CAS Number:
1783-96-6
Molecular Formula:
C4H7NO4
Molecular Weight:
133.1027
MDL Number:
MFCD00063081
IUPAC Name:
(2R)-2-aminobutanedioic acid
InChI:
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChI Key:
CKLJMWTZIZZHCS-UWTATZPHSA-N
SMILES:
OC(=O)C[C@H](C(=O)O)N
EC Number:
217-234-6
UNII:
4SR0Q8YD1X

Properties

Complexity:
133  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
133.038g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
133.103g/mol
Monoisotopic Mass:
133.038g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
101A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.8  

Literature

Title Journal
Central administration of L- and D-aspartate attenuates stress behaviors by social isolation and CRF in neonatal chicks. Amino acids 20121101
New insights on the role of free D-aspartate in the mammalian brain. Amino acids 20121101
D-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems. Amino acids 20121101
D-Amino acids in brain neurotransmission and synaptic plasticity. Amino acids 20121101
D-Amino acids in the brain and mutant rodents lacking D-amino-acid oxidase activity. Amino acids 20121101
Induced synthesis of P450 aromatase and 17β-estradiol by D-aspartate in frog brain. The Journal of experimental biology 20121015
Ovarian teratoma associated with anti-N-methyl D-aspartate receptor encephalitis: a report of 5 cases documenting prominent intratumoral lymphoid infiltrates. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20120901
Discriminating D-amino acid-containing peptide epimers by radical-directed dissociation mass spectrometry. Analytical chemistry 20120807
Co-localisation of advanced glycation end products and D-β-aspartic acid-containing proteins in gelatinous drop-like corneal dystrophy. The British journal of ophthalmology 20120801
Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica. Brain and behavior 20120701
Increased [³H]D-aspartate release and changes in glutamate receptor expression in the hippocampus of the mnd mouse. Journal of neuroscience research 20120601
Crystallization and preliminary crystallographic analysis of D-aspartate oxidase from porcine kidney. Acta crystallographica. Section F, Structural biology and crystallization communications 20120601
Conserved asparagine residue located in binding pocket controls cation selectivity and substrate interactions in neuronal glutamate transporter. The Journal of biological chemistry 20120518
Activation of glutamate transport evokes rapid glutamine release from perisynaptic astrocytes. The Journal of physiology 20120515
Oostatic peptides containing D-amino acids: synthesis, oostatic activity, degradation, accumulation in ovaries and NMR study. Amino acids 20120501
A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior. Molecular psychiatry 20120501
Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes. Glia 20120501
In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate. Glia 20120501
The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425
Chemical activation of a high-affinity glutamate transporter in human erythrocytes and its implications for malaria-parasite-induced glutamate uptake. Blood 20120412
The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies. Arquivos de neuro-psiquiatria 20120401
Regulation of [³H]d-aspartate release by the 5-F(2t)-isoprostane and its 5-epimer in isolated bovine retina. Neurochemical research 20120301
Unique ionotropic receptors for D-aspartate are a target for serotonin-induced synaptic plasticity in Aplysia californica. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120101
HPLC methods for determination of D-aspartate and N-methyl-D-aspartate. Methods in molecular biology (Clifton, N.J.) 20120101
Assays of D-amino acid oxidases. Methods in molecular biology (Clifton, N.J.) 20120101
Anti-N-methyl-D-aspartate-receptor encephalitis: cognitive profile in two children. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120101
A new splice variant of the glutamate-aspartate transporter: cloning and immunolocalization of GLAST1c in rat, pig and human brains. Journal of chemical neuroanatomy 20120101
Steroidogenic gene expression following D-aspartate treatment in frog testis. General and comparative endocrinology 20120101
The accessibility in the external part of the TM5 of the glutamate transporter EAAT1 is conformationally sensitive during the transport cycle. PloS one 20120101
Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level. Frontiers in neuroenergetics 20120101
Disruption of the serotonergic system after neonatal hypoxia-ischemia in a rodent model. Neurology research international 20120101
Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. International journal of Alzheimer's disease 20120101
Potassium dependent regulation of astrocyte water permeability is mediated by cAMP signaling. PloS one 20120101
The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain. Frontiers in molecular neuroscience 20120101
Negative modulation of NMDA receptor channel function by DREAM/calsenilin/KChIP3 provides neuroprotection? Frontiers in molecular neuroscience 20120101
Metabolic turnover of hydrogen sulfide. Frontiers in physiology 20120101
Characterization of an antibody that recognizes peptides containing D-β-aspartyl residues. Molecular vision 20120101
Identifying context-specific gene profiles of social, reproductive, and mate preference behavior in a fish species with female mate choice. Frontiers in neuroscience 20120101
Synaptic regulation of the hypothalamic-pituitary-adrenal axis and its modulation by glucocorticoids and stress. Frontiers in cellular neuroscience 20120101
Astrocytic adenosine A2A receptors control the amyloid-β peptide-induced decrease of glutamate uptake. Journal of Alzheimer's disease : JAD 20120101
Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia. Parkinson's disease 20120101
Increased D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice. Neurobiology of aging 20111201
Hippocampal AMPA autoreceptors positively coupled to NMDA autoreceptors traffic in a constitutive manner and undergo adaptative changes following enriched environment training. Neuropharmacology 20111201
Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source. Journal of neuroscience research 20111201
Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia. Experimental neurology 20111201
Emerging Pharmacological Properties of Cholinergic Synaptic Transmission: Comparison between Mammalian and Insect Synaptic and Extrasynaptic Nicotinic Receptors. Current neuropharmacology 20111201
Persistent increase of D-aspartate in D-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay. Neurobiology of aging 20111101
Simultaneous determination of D-aspartic acid and D-glutamic acid in rat tissues and physiological fluids using a multi-loop two-dimensional HPLC procedure. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Determination of D-aspartate N-methyltransferase activity in the starfish by direct analysis of N-methyl-D-aspartate with high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
D-Aspartate--an important bioactive substance in mammals: a review from an analytical and biological point of view. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Effect of D-aspartate uptake on uncoupling protein-3 and α-tubulin expressions in rat Harderian gland. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
D-Asp: a new player in reproductive endocrinology of the amphibian Rana esculenta. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y(1) receptors. British journal of pharmacology 20111101
HPLC determination of the distribution of D-amino acids and effects of ecdysis on alanine racemase activity in kuruma prawn Marsupenaeus japonicus. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
UV B-irradiation enhances the racemization and isomerizaiton of aspartyl residues and production of Nε-carboxymethyl lysine (CML) in keratin of skin. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
D-Amino acids in aged proteins: analysis and biological relevance. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Computational investigation of the substrate recognition mechanism of protein D-aspartyl (L-isoaspartyl) O-methyltransferase by docking and molecular dynamics simulation studies and application to interpret size exclusion chromatography data. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
D-Amino acid metabolism in mammals: biosynthesis, degradation and analytical aspects of the metabolic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro. Glia 20111101
Signaling through EAAT-1/GLAST in cultured Bergmann glia cells. Neurochemistry international 20111101
Comparison of molecular dynamics simulation methods for amyloid β(1-42) monomers containing D-aspartic acid residues for predicting retention times in chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Substrate stereoselectivity of mammalian D-aspartyl endopeptidase. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
A sensitive and simple ultra-high-performance-liquid chromatography-tandem mass spectrometry based method for the quantification of D-amino acids in body fluids. Journal of chromatography. A 20111007
Physiological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica neurons. Journal of neurophysiology 20111001
Post-traumatic stress disorder: the neurobiological impact of psychological trauma. Dialogues in clinical neuroscience 20110901
Substrate specificity of the aspartate:alanine antiporter (AspT) of Tetragenococcus halophilus in reconstituted liposomes. The Journal of biological chemistry 20110819
Synthesis of alanine-based colorimetric sensors and enantioselective recognition of aspartate and malate anions. Organic & biomolecular chemistry 20110807
Pain management in patients with cancer: focus on opioid analgesics. Current pain and headache reports 20110801
Immunohistochemical localization of D-aspartate oxidase in porcine peripheral tissues. Amino acids 20110701
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice. Cell and tissue research 20110701
Correction of furosemide-induced magnesium deficiency with different stereoisomers of organic magnesium salts: a comparative study. Bulletin of experimental biology and medicine 20110701
The role of the cerebellum in schizophrenia: from cognition to molecular pathways. Clinics (Sao Paulo, Brazil) 20110601
Cellular localization of glutamate and glutamine metabolism and transport pathways in the rat ciliary epithelium. Investigative ophthalmology & visual science 20110518
Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn. The Journal of comparative neurology 20110415
Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110323
D-Aspartic acid is a novel endogenous neurotransmitter. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110301
Expression of multiple glutamate transporter splice variants in the rodent testis. Asian journal of andrology 20110301
Specificity of the volume-activated amino acid efflux pathway in cultured human breast cancer cells. General physiology and biophysics 20110301
Role of the active site residues arginine-216 and arginine-237 in the substrate specificity of mammalian D-aspartate oxidase. Amino acids 20110201
Visible wavelength spectrophotometric assays of L-aspartate and D-aspartate using hyperthermophilic enzyme systems. Analytical biochemistry 20110201
Functional NMDA receptors with atypical properties are expressed in podocytes. American journal of physiology. Cell physiology 20110101
Distribution of D-aspartate-immunopositive cells in the ganglion cell layer of adult rat retina. Ophthalmic research 20110101
MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites. PloS one 20110101
Time course analysis of gene expression identifies multiple genes with differential expression in patients with in-stent restenosis. BMC medical genomics 20110101
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses. International journal of Alzheimer's disease 20110101
Galanin-immunoreactivity identifies a distinct population of inhibitory interneurons in laminae I-III of the rat spinal cord. Molecular pain 20110101
Proximity of transmembrane segments 5 and 8 of the glutamate transporter GLT-1 inferred from paired cysteine mutagenesis. PloS one 20110101
Postnatal development of dendrodendritic inhibition in the Mammalian olfactory bulb. Frontiers in cellular neuroscience 20110101
Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria. Journal of neuroinflammation 20110101
Immunohistochemical localization of endogenous D-Aspartate in the marine brown Alga Sargassum fusiforme. Bioscience, biotechnology, and biochemistry 20110101
Ketamine-induced oscillations in the motor circuit of the rat basal ganglia. PloS one 20110101
A role for glutamate transporters in the regulation of insulin secretion. PloS one 20110101
Histaminergic mechanisms for modulation of memory systems. Neural plasticity 20110101
Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn. Molecular pain 20110101
N-methyl D-aspartate receptor encephalitis: A new addition to the spectrum of autoimmune encephalitis. Annals of Indian Academy of Neurology 20110101
Slice orientation and muscarinic acetylcholine receptor activation determine the involvement of N-methyl D-aspartate receptor subunit GluN2B in hippocampal area CA1 long-term depression. Molecular brain 20110101
Preventive analgesia: Effect of small dose of ketamine on morphine requirement after renal surgery. Journal of anaesthesiology, clinical pharmacology 20110101
Co-induction of cyclooxygenase-2 [correction of cyclooxyenase-2] and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia. Molecular pain 20110101
Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat. PloS one 20110101
Comparative Structures and Evolution of Vertebrate Carboxyl Ester Lipase (CEL) Genes and Proteins with a Major Role in Reverse Cholesterol Transport. Cholesterol 20110101
Dynamic development of the first synapse impinging on adult-born neurons in the olfactory bulb circuit. Neural systems & circuits 20110101
Regulation of adult neurogenesis in the hippocampus by stress, acetylcholine and dopamine. Journal of natural science, biology, and medicine 20110101
An introduction to sphingolipid metabolism and analysis by new technologies. Neuromolecular medicine 20101201
Synthesis, accumulation, and release of d-aspartate in the Aplysia californica CNS. Journal of neurochemistry 20101201
Age estimation by amino acid racemization in human teeth. Journal of forensic sciences 20101101
AMPA- and P2X7-receptor-mediated facilitation of [3H]D-aspartate release from nerve terminals isolated from the rat caudal brainstem. Neurochemistry international 20101101
D-aspartate oxidase localisation in pituitary and pineal glands of the female pig. Journal of neuroendocrinology 20101101
On the catalytic role of the active site residue E121 of E. coli L-aspartate oxidase. Biochimie 20101001
Thiolactomycin inhibits D-aspartate oxidase: a novel approach to probing the active site environment. Biochimie 20101001
Distribution of radiolabeled l-glutamate and d-aspartate from blood into peripheral tissues in naive rats: significance for brain neuroprotection. Biochemical and biophysical research communications 20100903
Activation of a peroxisomal Pichia pastoris D-amino acid oxidase, which uses d-alanine as a preferred substrate, depends on pyruvate carboxylase. FEMS yeast research 20100901
A locus for an auditory processing deficit and language impairment in an extended pedigree maps to 12p13.31-q14.3. Genes, brain, and behavior 20100801
D-aspartate activates mGlu receptors coupled to polyphosphoinositide hydrolysis in neonate rat brain slices. Neuroscience letters 20100712
A conserved methionine residue controls the substrate selectivity of a neuronal glutamate transporter. The Journal of biological chemistry 20100709
Changes in D-aspartate ion currents in the Aplysia nervous system with aging. Brain research 20100709
Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius. American journal of physiology. Regulatory, integrative and comparative physiology 20100701
Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia. American journal of physiology. Regulatory, integrative and comparative physiology 20100701
Interaction of PGHS-2 and glutamatergic mechanisms controlling the ovine fetal hypothalamus-pituitary-adrenal axis. American journal of physiology. Regulatory, integrative and comparative physiology 20100701
HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway. PLoS pathogens 20100701
Methionine choline reverses lead-induced cognitive and N-methyl-d-aspartate receptor subunit 1 deficits. Toxicology 20100604
Growth hormone rescues hippocampal synaptic function after sleep deprivation. American journal of physiology. Regulatory, integrative and comparative physiology 20100601
Pax2 is expressed in a subpopulation of Müller cells in the central chick retina. Developmental dynamics : an official publication of the American Association of Anatomists 20100601
Collapse of homochirality of amino acids in proteins from various tissues during aging. Chemistry & biodiversity 20100601
Influence of oxidative stress on D-aspartyl endopeptidase activity. Chemistry & biodiversity 20100601
Molecular-dynamics simulations for amyloid beta 1-42 monomer with D-aspartic acid residues using continuous solvent. Chemistry & biodiversity 20100601
Accumulation of D-beta-aspartic acid-containing proteins in age-related ocular diseases. Chemistry & biodiversity 20100601
Structural consideration of mammalian D-aspartyl endopeptidase. Chemistry & biodiversity 20100601
Oxidative stress induces the formation of D-aspartyl residues in the elastin mimic peptides. Chemistry & biodiversity 20100601
Comparative characterization of three D-aspartate oxidases and one D-amino acid oxidase from Caenorhabditis elegans. Chemistry & biodiversity 20100601
D-aspartate oxidase: the sole catabolic enzyme acting on free D-aspartate in mammals. Chemistry & biodiversity 20100601
Effects of D-aspartate treatment on D-aspartate oxidase, superoxide dismutase, and caspase 3 activities in frog (Rana esculenta) tissues. Chemistry & biodiversity 20100601
Thyroid hormones and D-aspartic acid, D-aspartate oxidase, D-aspartate racemase, H2O2, and ROS in rats and mice. Chemistry & biodiversity 20100601
Translational neuroimaging research in pediatric obsessive-compulsive disorder. Dialogues in clinical neuroscience 20100601
Evidence for the involvement of D-aspartic acid in learning and memory of rat. Amino acids 20100501
Transportable and non-transportable inhibitors of L-glutamate uptake produce astrocytic stellation and increase EAAT2 cell surface expression. Neurochemical research 20100501
Protective effects of the pyrolyzates derived from bamboo against neuronal damage and hematoaggregation. Journal of ethnopharmacology 20100421
DL-Aspartic acid administration improves semen quality in rabbit bucks. Animal reproduction science 20100401
Magnesium for treatment-resistant depression: a review and hypothesis. Medical hypotheses 20100401
Muscarinic receptor stimulation of D-aspartate uptake into human SH-SY5Y neuroblastoma cells is attenuated by hypoosmolarity. The Journal of pharmacology and experimental therapeutics 20100401
D-Aspartic acid induced oxidative stress and mitochondrial dysfunctions in testis of prepubertal rats. Amino acids 20100301
Distribution of free D-aspartic acid and D-aspartate oxidase in frog Rana esculenta tissues. Journal of experimental zoology. Part A, Ecological genetics and physiology 20100301
Inhibitory effects of (2S, 3S)-3-[3-[4-(trifluoromethyl)benzoylamino]benzyloxy]aspartate (TFB-TBOA) on the astrocytic sodium responses to glutamate. Brain research 20100226
Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis. Proceedings of the National Academy of Sciences of the United States of America 20100216
The maturation of oocyte follicular epithelium of Podarcis s. sicula is promoted by D-aspartic acid. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20100201
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study. British journal of pharmacology 20100201
Structural remodeling of gray matter astrocytes in the neonatal pig brain after hypoxia/ischemia. Glia 20100115
D-Aspartate binding sites in rat Harderian gland. Amino acids 20100101
Glutamate spillover augments GABA synthesis and release from axodendritic synapses in rat hippocampus. Hippocampus 20100101
Effects of extracellular pH reductions on [(3)H]D-aspartate and [(3)H]noradrenaline release by presynaptic nerve terminals isolated from rat cerebral cortex. Journal of neural transmission (Vienna, Austria : 1996) 20100101
Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans. BMC systems biology 20100101
Activation of AMPA receptors in the suprachiasmatic nucleus phase-shifts the mouse circadian clock in vivo and in vitro. PloS one 20100101
The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors. The open medicinal chemistry journal 20100101
Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis. Biology direct 20100101
Age and diet affect gene expression profiles in canine liver tissue. PloS one 20100101
Trace eyeblink conditioning is impaired in α7 but not in β2 nicotinic acetylcholine receptor knockout mice. Frontiers in behavioral neuroscience 20100101
Characterisation of the expression of NMDA receptors in human astrocytes. PloS one 20100101
The emerging chondrocyte channelome. Frontiers in physiology 20100101
Thrombin potentiates D-aspartate efflux from cultured astrocytes under conditions of K+ homeostasis disruption. Journal of neurochemistry 20091201
Regulation of [3H] D-aspartate release from mammalian isolated retinae by hydrogen sulfide. Neurochemical research 20091101
Angelman syndrome: current understanding and research prospects. Epilepsia 20091101
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. Archives of biochemistry and biophysics 20091015
D-Aspartate affects secretory activity in rat Harderian gland: molecular mechanism and functional significance. Amino acids 20091001
Distribution of glutamate transporter GLAST in membranes of cultured astrocytes in the presence of glutamate transport substrates and ATP. Neurochemical research 20091001
Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes. Neurochemical research 20091001
Quantitative analysis of the expression of the glutamate-aspartate transporter and identification of functional glutamate uptake reveal a role for cochlear fibrocytes in glutamate homeostasis. Neuroscience 20090915
Release of [3H]D-aspartate induced by K+-stimulation is increased in the cervical spinal cord of the wobbler mouse: a model of motor neuron disease. Neurochemistry international 20090901
Quantification of D-Asp and D-Glu in rat brain and human cerebrospinal fluid by microchip electrophoresis. Journal of separation science 20090901
L-aspartate as an amino acid neurotransmitter: mechanisms of the depolarization-induced release from cerebrocortical synaptosomes. Journal of neurochemistry 20090801
Axonal release of glutamate analog, d-2,3-3H-Aspartic acid and l-14C-proline from segments of sciatic nerve following electrical and magnetic stimulation. Neuroscience letters 20090710
Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity. Glia 20090701
Immunohistochemical localisation of D-beta-aspartic acid in pingueculae. The British journal of ophthalmology 20090701
Immunohistochemical localisation of D-beta-aspartic acid-containing proteins in climatic droplet keratopathy. The British journal of ophthalmology 20090701
HPLC determination of acidic D-amino acids and their N-methyl derivatives in biological tissues. Biomedical chromatography : BMC 20090601
Neuropeptide S selectively inhibits the release of 5-HT and noradrenaline from mouse frontal cortex nerve endings. British journal of pharmacology 20090601
The reproductive activity in the testis of Podarcis s. sicula involves D-aspartic acid: a study on c-kit receptor protein, tyrosine kinase activity and PCNA protein during annual sexual cycle. General and comparative endocrinology 20090501
Localization of D-β-aspartyl residue-containing proteins in various tissues. International journal of molecular sciences 20090501
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels. Journal of neurochemistry 20090401
Demequina lutea sp. nov., isolated from a high Arctic permafrost soil. International journal of systematic and evolutionary microbiology 20090401
Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. Environmental health perspectives 20090401
Blockade of glutamate transporters facilitates cerebellar synaptic long-term depression. Neuroreport 20090325
Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug. Behavioural brain research 20090302
Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats. Behavioural brain research 20090302
Metabolic stress-like condition can be induced by prolonged strenuous exercise in athletes. Upsala journal of medical sciences 20090301
The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats. PLoS genetics 20090301
Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors. Central nervous system agents in medicinal chemistry 20090301
No association between the D-aspartate oxidase locus and schizophrenia. Psychiatric genetics 20090201
Molecular cloning and expression in Escherichia coli of an active fused Zea mays L. D-amino acid oxidase. Biochemistry. Biokhimiia 20090201
Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents. Neuroscience 20090112
Memantine (Namenda) for neuropathic pain. The American journal of hospice & palliative care 20090101
Gene expression patterns in hypoxic and post-hypoxic adult rat retina with special reference to the NMDA receptor and its interactome. Molecular vision 20090101
The photosynthetic apparatus and its regulation in the aerobic gammaproteobacterium Congregibacter litoralis gen. nov., sp. nov. PloS one 20090101
NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum. PloS one 20090101
Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes. Molecular pain 20090101
Functional imaging of stimulus convergence in amygdalar neurons during Pavlovian fear conditioning. PloS one 20090101
Left auditory cortex gamma synchronization and auditory hallucination symptoms in schizophrenia. BMC neuroscience 20090101
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NMDA receptor hypofunction leads to generalized and persistent aberrant gamma oscillations independent of hyperlocomotion and the state of consciousness. PloS one 20090101
Signals, synapses, and synthesis: how new proteins control plasticity. Frontiers in neural circuits 20090101
The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reproductive biology and endocrinology : RB&E 20090101
The functional consequences of cortical circuit abnormalities on gamma oscillations in schizophrenia: insights from computational modeling. Frontiers in human neuroscience 20090101
NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia. Progress in brain research 20090101
D-aspartate: an atypical amino acid with neuromodulatory activity in mammals. Reviews in the neurosciences 20090101
RANTES modulates the release of glutamate in human neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience 20081111
L-glutamate enhances methylmercury toxicity by synergistically increasing oxidative stress. Journal of pharmacological sciences 20081101
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081022
D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081008
Functional glutamate transport in rodent optic nerve axons and glia. Glia 20080901
Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from mouse cortical nerve endings. Neuropharmacology 20080901
Abundance and activity of Chloroflexi-type SAR202 bacterioplankton in the meso- and bathypelagic waters of the (sub)tropical Atlantic. Environmental microbiology 20080701
Oxidative alterations induced by D-aspartic acid in prepubertal rat testis in vitro: a mechanistic study. Theriogenology 20080701
Low-affinity excitatory amino acid uptake in hippocampal astrocytes: a possible role of Na+/dicarboxylate cotransporters. Glia 20080701
The effects of acute intraocular pressure elevation on rat retinal glutamate transport. Acta ophthalmologica 20080601
Hyperactive mutants of mouse D-aspartate oxidase: mutagenesis of the active site residue serine 308. Amino acids 20080601
Collagen turnover in normal and degenerate human intervertebral discs as determined by the racemization of aspartic acid. The Journal of biological chemistry 20080404
D-Aspartate and D-aspartate oxidase show selective and developmentally dynamic localization in mouse retina. Experimental eye research 20080401
[Biochemical behavior and function of free D-aspartate in the mammalian body]. Seikagaku. The Journal of Japanese Biochemical Society 20080401
[Racemization of aspartyl residues of proteins in age-related disease]. Seikagaku. The Journal of Japanese Biochemical Society 20080401
[Distribution of free D-amino acids and their biosyntheses and physiological roles in aquatic animals]. Seikagaku. The Journal of Japanese Biochemical Society 20080401
In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080301
Structure of aspartate racemase complexed with a dual substrate analogue, citric acid, and implications for the reaction mechanism. Proteins 20080301
Cloning and functional characterization of Arabidopsis thaliana D-amino acid aminotransferase--D-aspartate behavior during germination. The FEBS journal 20080301
Treatment of COPD: a matrix perspective. International journal of chronic obstructive pulmonary disease 20080301
Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility. Molecular and cellular neurosciences 20080201
Na(+)-Ca(2+) cosignaling in the stimulation of the glucose transporter GLUT1 in cultured astrocytes. Glia 20080101
Latitudinal trends of Crenarchaeota and Bacteria in the meso- and bathypelagic water masses of the Eastern North Atlantic. Environmental microbiology 20080101
[Potassium magnesium homeostasis: physiology, pathophysiology, clinical consequences of deficiency and pharmacological correction]. Uspekhi fiziologicheskikh nauk 20080101
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. BMC biochemistry 20080101
Opposing effects of D-aspartic acid and nitric oxide on tuning of testosterone production in mallard testis during the reproductive cycle. Reproductive biology and endocrinology : RB&E 20080101
Altered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of Schizophrenia. Frontiers in molecular neuroscience 20080101
Comparison of [(3)H]-(2S,4R)-4-methylglutamate and [(3)H]D-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters. Neurochemistry international 20071201
Reproductive implication of D-aspartic acid in human pre-ovulatory follicular fluid. Human reproduction (Oxford, England) 20071201
[Role of isomerized protein repair enzyme, PIMT, in cellular functions]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071201
Upregulation of elastin expression in constrictive bronchiolitis obliterans. International journal of chronic obstructive pulmonary disease 20071201
Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by 'pathologically' elevated extraterminal K+ concentrations. Journal of neurochemistry 20071101
Adult astroglia is competent for Na+/Ca2+ exchanger-operated exocytotic glutamate release triggered by mild depolarization. Journal of neurochemistry 20071101
Ammonium scanning in an enzyme active site. The chiral specificity of aspartyl-tRNA synthetase. The Journal of biological chemistry 20071019
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Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia. Biological psychiatry 20071001
Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome. The FEBS journal 20071001
Effect of the L- or D-aspartate on ecto-5'nucleotidase activity and on cellular viability in cultured neurons: participation of the adenosine A(2A) receptors. Amino acids 20070901
Localization of D-beta-aspartic acid-containing proteins in human eyes. Investigative ophthalmology & visual science 20070901
Ethanolamine and related amino alcohols increase basal and evoked release of [3H]-D-aspartic acid from synaptosomes by enhancing the filling of synaptic vesicles. European journal of pharmacology 20070702
Evidence that alpha7 nicotinic receptor modulates glutamate release from mouse neocortical gliosomes. Neurochemistry international 20070701
Exocytosis of D-aspartate from INS-1E clonal beta cells. Biological & pharmaceutical bulletin 20070701
Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes. Biochemical pharmacology 20070615
Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/gamma subunit of Na, K-ATPase in human fetal astrocytes. Neurochemistry international 20070601
D-amino acid formation in sterilized alkali-treated olives. Journal of agricultural and food chemistry 20070502
Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflugers Archiv : European journal of physiology 20070501
Overproduction and characterization of a recombinant D-amino acid oxidase from Arthrobacter protophormiae. Applied microbiology and biotechnology 20070401
Can levorphanol be used like methadone for intractable refractory pain? Journal of palliative medicine 20070401
Age-dependent changes in the racemisation ratio of aspartic acid in human alveolar bone. Archives of oral biology 20070301
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. Biochimie 20070301
Serotonin modulation of cell excitability and of [3H]GABA and [3H]D-aspartate efflux in primary cultures of rat cortical neurons. Neuropharmacology 20070301
Functional and structural characterization of D-aspartate oxidase from porcine kidney: non-Michaelis kinetics due to substrate activation. Journal of biochemistry 20070301
D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role. Brain research reviews 20070201
Protein kinase C-mediated modulation of glutamate transporter activity in rat retina. Current eye research 20070201
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature 20070125
D-Aspartic acid and nitric oxide as regulators of androgen production in boar testis. Theriogenology 20070115
Biochemistry of D-aspartate in mammalian cells. Amino acids 20070101
Effects of D-amino acids on lipoperoxidation in rat liver and kidney mitochondria. Amino acids 20070101
Advances in immunoanalysis of single cells with capillary electrophoresis. Analytical and bioanalytical chemistry 20070101
Isolation and characterization of mammalian D-aspartyl endopeptidase. Amino acids 20070101
Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases. The FEBS journal 20070101
D-aspartic acid and L-amino acids in the neural system of the amphioxus Branchiostoma lanceolatum. Amino acids 20070101
Is there a correlation between age and D-aspartic acid in human knee cartilage? Amino acids 20070101
Involvement of D-Asp in P450 aromatase activity and estrogen receptors in boar testis. Amino acids 20070101
Modulation of an AMPA-like glutamate receptor (SqGluR) gating by L- and D-aspartic acids. Amino acids 20070101
Molecular cloning of a cDNA encoding mouse D-aspartate oxidase and functional characterization of its recombinant proteins by site-directed mutagenesis. Amino acids 20070101
Species differences in brain gene expression profiles associated with adult behavioral maturation in honey bees. BMC genomics 20070101
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. Theoretical biology & medical modelling 20070101
N-methyl-D-aspartic acid (NMDA) in the nervous system of the amphioxus Branchiostoma lanceolatum. BMC neuroscience 20070101
5-Hydroxytryptamine-mediated increase in glutamate uptake by the leech giant glial cell. Glia 20061201
Biochemistry of amino acid racemization and clinical application to musculoskeletal disease. Clinical biochemistry 20061201
Identification of an essential gene responsible for D-Asp incorporation in the Lactococcus lactis peptidoglycan crossbridge. Molecular microbiology 20061201
Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain. British journal of pharmacology 20061101
The substrate specificity of a neuronal glutamate transporter is determined by the nature of the coupling ion. Journal of neurochemistry 20061001
Behavioural alterations in male mice lacking the gene for D-aspartate oxidase. Behavioural brain research 20060810
Occurrence of D-aspartate in the harderian gland of Podarcis s. sicula and its effect on gland secretion. Journal of experimental zoology. Part A, Comparative experimental biology 20060801
Cryptic expression of functional glutamate transporters in the developing rodent brain. Neuron glia biology 20060801
Metabolic properties of astrocytes differentiated from rat neurospheres. Brain research 20060726
The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060719
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A physiological mechanism to regulate D-aspartic acid and NMDA levels in mammals revealed by D-aspartate oxidase deficient mice. Gene 20060607
Immunohistochemical localization of D-aspartate in islets of Langerhans. Biological & pharmaceutical bulletin 20060601
The influence of manufacture on the free D-amino acid content of Cheddar cheese. Amino acids 20060601
Differential analysis of D-beta-Asp-containing proteins found in normal and infrared irradiated rabbit lens. Biochemical and biophysical research communications 20060526
Engineering the substrate specificity of porcine kidney D-amino acid oxidase by mutagenesis of the 'active-site lid'. Journal of biochemistry 20060501
Aslfm, the D-aspartate ligase responsible for the addition of D-aspartic acid onto the peptidoglycan precursor of Enterococcus faecium. The Journal of biological chemistry 20060428
D-aspartate and reproductive activity in sheep. Theriogenology 20060415
D-Aspartate as a putative cell-cell signaling molecule in the Aplysia californica central nervous system. Journal of neurochemistry 20060401
D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060308
Mini-alphaB-crystallin: a functional element of alphaB-crystallin with chaperone-like activity. Biochemistry 20060307
The presence of high concentrations of free D-amino acids in human saliva. Life sciences 20060306
D-aspartic acid in the nervous system of Aplysia limacina: possible role in neurotransmission. Journal of cellular physiology 20060301
Mercuric chloride inhibits the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells. Biological trace element research 20060301
Confirmation of peak assignments in capillary electrophoresis using immunoprecipitation. Application to D-aspartate measurements in neurons. Journal of chromatography. A 20060217
Cytoplasmic localization and efflux of endogenous D-aspartate in pheochromocytoma 12 cells. Archives of biochemistry and biophysics 20060215
Oxidative metabolism in cultured rat astroglia: effects of reducing the glucose concentration in the culture medium and of D-aspartate or potassium stimulation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060201
Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate. Journal of neurochemistry 20060201
Endogenous testicular D-aspartic acid regulates gonadal aromatase activity in boar. Journal of endocrinological investigation 20060201
Release of tritiated agmatine from spinal synaptosomes. Neuroreport 20060123
High glucose and diabetes increase the release of [3H]-D-aspartate in retinal cell cultures and in rat retinas. Neurochemistry international 20060101
High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes. Neurochemistry international 20060101
Domain-based small molecule binding site annotation. BMC bioinformatics 20060101
EAAC1 is expressed in rat and human prostate epithelial cells; functions as a high-affinity L-aspartate transporter; and is regulated by prolactin and testosterone. BMC biochemistry 20060101
Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. International journal of biological sciences 20060101
Inhibition of potassium- and ischemia-evoked [3H] D-aspartate release from isolated bovine retina by cannabinoids. Current eye research 20060101
[Comparative study of the antiarrhythmic activity of magnesium aspartate L-, D- and DL-aspartate stereoisomers]. Kardiologiia 20060101
S1 gene sequence analysis of a nephropathogenic strain of avian infectious bronchitis virus in Egypt. Virology journal 20060101
Occurrence and functions of free D-aspartate and its metabolizing enzymes. Chemical record (New York, N.Y.) 20060101
Mathematical modeling of intracellular signaling pathways. BMC neuroscience 20060101
The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by manganese. Biological trace element research 20051201
Endocrine roles of D-aspartic acid in the testis of lizard Podarcis s. sicula. The Journal of endocrinology 20051201
Subcellular analysis of D-aspartate. Analytical chemistry 20051115
Pharmacological consequences of oxidative stress in ocular tissues. Mutation research 20051111
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Physiological role of D-aspartate oxidase in the assimilation and detoxification of D-aspartate in the yeast Cryptococcus humicola. Yeast (Chichester, England) 20051101
An application of D- and L-aspartic acid mixtures as standard specimens for the chronological age estimation. Journal of forensic sciences 20051101
Glutamate release induced by activation of glycine and GABA transporters in spinal cord is enhanced in a mouse model of amyotrophic lateral sclerosis. Neurotoxicology 20051001
Characterization of new D-beta-aspartate-containing proteins in a lens-derived cell line. Biochemical and biophysical research communications 20050909
Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake. Neuroscience research 20050901
Free D-aspartate in mammals. Biological & pharmaceutical bulletin 20050901
Physiological function and metabolism of free D-alanine in aquatic animals. Biological & pharmaceutical bulletin 20050901
Modification of the synaptic glutamate turnover in the hippocampal tissue exposed to low-frequency, pulsed magnetic fields. Brain research 20050809
D-aspartate modulates transcriptional activity in Harderian gland of frog, Rana esculenta: Morphological and molecular evidence. Journal of cellular physiology 20050801
Protein L-isoaspartyl methyltransferase catalyzes in vivo racemization of Aspartate-25 in mammalian histone H2B. The Journal of biological chemistry 20050715
Retinal bipolar cell input mechanisms in giant danio. III. ON-OFF bipolar cells and their color-opponent mechanisms. Journal of neurophysiology 20050701
Substrate-induced modulation of glutamate uptake in human platelets. British journal of pharmacology 20050701
D-amino acids in the central nervous system in health and disease. Molecular genetics and metabolism 20050701
Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro. Neuropharmacology 20050701
D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons. British journal of pharmacology 20050601
Chronic nicotine differentially affects the function of nicotinic receptor subtypes regulating neurotransmitter release. Journal of neurochemistry 20050601
A novel L-glutamate transporter inhibitor reveals endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells. Life sciences 20050506
Activation of gamma-aminobutyric acid GAT-1 transporters on glutamatergic terminals of mouse spinal cord mediates glutamate release through anion channels and by transporter reversal. Journal of neuroscience research 20050501
Effects of hypoxic and osmotic stress on the free D-aspartate level in the muscle of blood shell Scapharca broughtonii. Amino acids 20050501
[D-amino acid biosystem in mammals]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20050501
Esterification of Escherichia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases. Bioscience, biotechnology, and biochemistry 20050501
Synthesis and characterization of 4-methoxy-7-nitroindolinyl-D-aspartate, a caged compound for selective activation of glutamate transporters and N-methyl-D-aspartate receptors in brain tissue. Biochemistry 20050308
Cephalopod vision involves dicarboxylic amino acids: D-aspartate, L-aspartate and L-glutamate. The Biochemical journal 20050301
Racemization in enamel among different types of teeth from the same individual. International journal of legal medicine 20050301
Calcium regulates the mode of exocytosis induced by hypotonic shock in isolated neuronal presynaptic endings. Neurochemistry international 20050201
Glutamate transport by retinal Muller cells in glutamate/aspartate transporter-knockout mice. Glia 20050115
Retinal bipolar cell input mechanisms in giant danio. II. Patch-clamp analysis of on bipolar cells. Journal of neurophysiology 20050101
Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels. Biochemical pharmacology 20050101
Glutamate uptake by rat brain astroglia incubated in human cerebrospinal fluid. Medical science monitor : international medical journal of experimental and clinical research 20050101
Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype. Neurotoxicity research 20050101
Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: role of arachidonic acid metabolites. Neurochemical research 20050101
Vitamin A deficiency alters the pulmonary parenchymal elastic modulus and elastic fiber concentration in rats. Respiratory research 20050101
In vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells is inhibited by the ethylmercury-containing preservative thimerosal. Biological trace element research 20050101
[Lanthanides induce neurotransmitter release from the vesicular pool in rat brain synaptosomes]. Biofizika 20050101
Potentiation of the osmosensitive release of taurine and D-aspartate from SH-SY5Y neuroblastoma cells after activation of M3 muscarinic cholinergic receptors. The Journal of pharmacology and experimental therapeutics 20041201
Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study. Neurochemistry international 20041201
Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum. European journal of biochemistry 20041201
[Degradation of biomolecules: a comparative study of diagenesis of DNA and proteins in human bone tissue]. Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur 20041201
Retinal glutamate transporter activity persists under simulated ischemic conditions. Journal of neuroscience research 20041115
In vitro differentiated neural stem cells express functional glial glutamate transporters. Neuroscience letters 20041111
Effects of nociceptin/orphanin FQ and endomorphin-1 on glutamate and GABA release, intracellular [Ca2+] and cell excitability in primary cultures of rat cortical neurons. Neuropharmacology 20041101
Glutamate efflux from human cerebrocortical slices during ischemia: vesicular-like mode of glutamate release and sensitivity to A(2A) adenosine receptor blockade. Neuropharmacology 20041101
Effects of glutamate transport substrates and glutamate receptor ligands on the activity of Na-/K(+)-ATPase in brain tissue in vitro. Clinical and experimental pharmacology & physiology 20041101
Formation of D-tyrosyl-tRNATyr accounts for the toxicity of D-tyrosine toward Escherichia coli. The Journal of biological chemistry 20041008
5-HT control of ischemia-evoked glutamate efflux from human cerebrocortical slices. Neurochemistry international 20041001
Glutamate transporter localization does not correspond to the temporary functional recovery and late degeneration after acute ocular ischemia in rats. Experimental eye research 20041001
Continuous on-line derivatization and selective separation of D-aspartic acid by a capillary electrophoresis system with a continuous sample introduction interface. Electrophoresis 20041001
Determination of amino acids in rat vitreous perfusates by capillary electrophoresis. Electrophoresis 20040901
Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus. Neurochemical research 20040801
Interaction between intrathecal gabapentin and adenosine in the formalin test of rats. Journal of Korean medical science 20040801
Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids. Neuropharmacology 20040701
NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice. Epilepsia 20040701
Measurement of glutamate uptake and reversed transport by rat synaptosome transporters. Biological & pharmaceutical bulletin 20040601
Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking. Brain research. Molecular brain research 20040519
Excessive and precocious glutamate release in a mouse model of amyotrophic lateral sclerosis. Neuropharmacology 20040501
Comparison of age estimated from degree of racemization of aspartic acid, glutamic acid and alanine in the femur. Journal of forensic sciences 20040501
Arachidonic acid metabolites and peroxide-induced inhibition of [3H]D-aspartate release from bovine isolated retinae. Current eye research 20040501
L-Glutamate in the extracellular space regulates endogenous D-aspartate homeostasis in rat pheochromocytoma MPT1 cells. Archives of biochemistry and biophysics 20040401
Effects of L-glutamate/D-aspartate and monensin on lactic acid production in retina and cultured retinal Müller cells. Journal of neurochemistry 20040401
Effect of peroxides on [3H]D-aspartate release from bovine isolated retinae. Neurochemical research 20040401
Cloning and expression in Escherichia coli of the D-aspartate oxidase gene from the yeast Cryptococcus humicola and characterization of the recombinant enzyme. Journal of biochemistry 20040401
Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes. Journal of neuroscience research 20040315
Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings through presynaptic sst2 receptors linked to the adenylyl cyclase-protein kinase A pathway. Neuropharmacology 20040301
Noise trauma alters D-[3H]aspartate release and AMPA binding in chinchilla cochlear nucleus. Journal of neuroscience research 20040215
Diversity of functional astroglial properties in the respiratory network. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040211
M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040121
Immunohistochemical study of chronological and photo-induced aging skins using the antibody raised against D-aspartyl residue-containing peptide. Journal of cutaneous pathology 20040101
Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. Journal of neurochemistry 20040101
Neurotransmitter release in experimental stroke models: the role of glutamate-GABA interaction. Advances in experimental medicine and biology 20040101
Glutamate-induced inhibition of D-aspartate uptake in Müller glia from the retina. Neurochemical research 20040101
[Influence of calcium ionophore A23187 on neurotransmitter release in rat brain synaptosomes]. Biofizika 20040101
Free D-aspartic acid in rat salivary glands. Archives of biochemistry and biophysics 20031201
Molecular characterization of D-amino acid oxidase from common carp Cyprinus carpio and its induction with exogenous free D-alanine. Archives of biochemistry and biophysics 20031201
Regulation of the Na+-dependent glutamate/aspartate transporter in rodent cerebellar astrocytes. Neurochemical research 20031201
Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
WAY-855 (3-amino-tricyclo[2.2.1.02.6]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake. British journal of pharmacology 20031101
First evidence on induced topological changes in supercoiled DNA by an aluminium D-aspartate complex. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20031101
Effect of hydrogen peroxide on amino acid concentrations in bovine retina and vitreous humor, ex vivo. Methods and findings in experimental and clinical pharmacology 20031101
Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices. Journal of neurochemistry 20030901
Location of putative glutamatergic neurons projecting to the medial preoptic area of the rat hypothalamus. Brain research bulletin 20030830
The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase. The Biochemical journal 20030801
Changes in NPY-mediated modulation of hippocampal [3H]D-aspartate outflow in the kindling model of epilepsy. Synapse (New York, N.Y.) 20030801
Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. Glia 20030801
A receptor for presynaptic glutamatergic autoinhibition is a glutamate transporter. The European journal of neuroscience 20030801
Effects of ammonia on high affinity glutamate uptake and glutamate transporter EAAT3 expression in cultured rat cerebellar granule cells. Neurochemistry international 20030701
Functional characterization of a glutamate/aspartate transporter from the mosquito Aedes aegypti. The Journal of experimental biology 20030701
Stimulation of sodium pump restores membrane potential to neurons excited by glutamate in zebrafish distal retina. The Journal of physiology 20030615
Differences in the D/L aspartic acid ratios in dentin among different types of teeth from the same individual and estimated age. International journal of legal medicine 20030601
An investigation into the role of calcium in the modulation of rat synaptosomal D-[3H]aspartate transport by docosahexaenoic acid. Brain research 20030523
Immunological detection of D-beta-aspartate-containing protein in lens-derived cell lines. Molecular vision 20030522
An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids. Neurochemistry international 20030501
The possible role of glutamate uptake in metaphit-induced seizures. Neurochemical research 20030501
Metabotropic glutamate receptor-mediated hetero-synaptic interaction of red- and green-cone inputs to LHC of carp retina. Brain research bulletin 20030415
Nucleotides modulate the activity of aspartate racemase of Scapharca broughtonii. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030401
Adenosine-induced modulation of excitatory amino acid transport across isolated brain arterioles. Journal of neurosurgery 20030301
Activation of a glycine transporter on spinal cord neurons causes enhanced glutamate release in a mouse model of amyotrophic lateral sclerosis. British journal of pharmacology 20030301
P2X7 receptor-mediated release of excitatory amino acids from astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215
Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues. Journal of experimental zoology. Part A, Comparative experimental biology 20030201
The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. Journal of neurochemistry 20030201
Purification and characterization of aspartate racemase from the bivalve mollusk Scapharca broughtonii. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030201
Presence of free D-amino acids in microalgae. Bioscience, biotechnology, and biochemistry 20030201
N-methyl-D-glutamate and N-methyl-L-glutamate in Scapharca broughtonii (Mollusca) and other invertebrates. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030101
Effect of D-amino acids on some mitochondrial functions in rat liver. Amino acids 20030101
Asymmetry of glutamine transporters in cultured neural cells. Neurochemistry international 20030101
Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems. Bioconjugate chemistry 20030101
Inhibitory effect of some neuroactive steroids on cocaine-induced kindling in mice. Polish journal of pharmacology 20030101
Activation of glutamate transporters in rods inhibits presynaptic calcium currents. Visual neuroscience 20030101
Amino acid racemases: functions and mechanisms. Journal of bioscience and bioengineering 20030101
The effect of D-aspartate on luteinizing hormone-releasing hormone, alpha-melanocyte-stimulating hormone, GABA and dopamine release. Neuroreport 20021203
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices. British journal of pharmacology 20021201
The consequences of methylmercury exposure on interactive functions between astrocytes and neurons. Neurotoxicology 20021201
Technical notes for age estimation using the femur: influence of various analytical conditions on D-aspartic acid contents. International journal of legal medicine 20021201
Mechanism of superoxide and hydrogen peroxide formation by fumarate reductase, succinate dehydrogenase, and aspartate oxidase. The Journal of biological chemistry 20021108
Dose-dependent effects of prenatal ethanol exposure on synaptic plasticity and learning in mature offspring. Alcoholism, clinical and experimental research 20021101
D-Aspartic acid in bovine dentine non-collagenous phosphoprotein. Archives of oral biology 20021101
Tyrosine kinases and amino acid efflux under hyposmotic and ischaemic conditions in the chicken retina. Pflugers Archiv : European journal of physiology 20021001
[Studies on the cytological function of the biomembrane and the neurons]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021001
Cellular architecture of the nucleus reuniens thalami and its putative aspartatergic/glutamatergic projection to the hippocampus and medial septum in the rat. The European journal of neuroscience 20021001
Ferrous-iron-dependent uptake of L-glutamate by a mesophilic, mixotrophic iron-oxidizing bacterium strain OKM-9. Bioscience, biotechnology, and biochemistry 20021001
A specific enzymatic high-performance liquid chromatography method to determine N-methyl-D-aspartic acid in biological tissues. Analytical biochemistry 20020901
Glutamate uptake is inhibited by tamoxifen and toremifene in cultured retinal pigment epithelial cells. Pharmacology & toxicology 20020901
Cellular and subcellular distribution of D-aspartate oxidase in human and rat brain. The Journal of comparative neurology 20020826
Aluminum L-glutamate complex in rat brain cortex: in vivo prevention of aluminum deposit by magnesium D-aspartate. Brain research 20020816
Cell density inversely regulates D- and L-aspartate levels in rat pheochromocytoma MPT1 cells. Archives of biochemistry and biophysics 20020801
Engineering the substrate specificity of D-amino-acid oxidase. The Journal of biological chemistry 20020726
The presence of D-beta-aspartic acid-containing peptides in elastic fibers of sun-damaged skin: a potent marker for ultraviolet-induced skin aging. Biochemical and biophysical research communications 20020628
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes. British journal of pharmacology 20020601
A novel method for in vitro production of human glial-like cells from neurosurgical resection tissue. Laboratory investigation; a journal of technical methods and pathology 20020601
Effect of allopregnanolone on d-[3H]-aspartate release and [3H]-glutamate uptake in the hippocampus of kainate-treated mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601
Protein kinase C regulates [3H]D-aspartate release in auditory brain stem nuclei. Experimental neurology 20020501
Effect of ionotropic and metabotropic glutamate agonists and D-aspartate on prolactin release from anterior pituitary cells. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020501
Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ. Journal of neurochemistry 20020501
Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter. The Journal of biological chemistry 20020419
Benzodiazepines differently modulate EAAT1/GLAST and EAAT2/GLT1 glutamate transporters expressed in CHO cells. Neurochemistry international 20020401
Insulin-like growth factor-1 increases activity and surface levels of the GLAST subtype of glutamate transporter. Neurochemistry international 20020401
Glutamate uptake controls expression of a slow postsynaptic current mediated by mGluRs in cerebellar Purkinje cells. Journal of neurophysiology 20020401
D-amino acids in living higher organisms. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020401
Differences between D- and L-aspartate binding to the Na+-dependent binding sites on glutamate transporters in frozen sections of rat brain. Life sciences 20020118
Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology. Journal of medicinal chemistry 20020103
Naturally occurring free D-aspartate is a nuclear component of cells in the mammalian hypothalamo-neurohypophyseal system. Neuroscience 20020101
Modulation of glial glutamate transport through cell interactions with the extracellular matrix. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20020101
Age-related changes in the D-aspartic acid content of the cranial bones in senescence-accelerated mice (SAM). Growth, development, and aging : GDA 20020101
In vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study. Journal of neuroscience research 20011215
Occurrence of N-methyl-L-aspartate in bivalves and its distribution compared with that of N-methyl-D-aspartate and D,L-aspartate. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011201
Activation of alpha 6 GABAA receptors on depolarized cerebellar parallel fibers elicits glutamate release through anion channels. Neuropharmacology 20011201
Substrate exchange properties of the high-affinity glutamate transporter EAAT2. Journal of neuroscience research 20011101
Effects of metabotropic glutamate receptor agonists and antagonists on D-aspartate release from mouse cerebral cortical and striatal slices. Neurochemical research 20011101
Hypoxia-induced [(3)H]D-aspartate release from isolated bovine retina: modulation by calcium-channel blockers and glutamatergic agonists and antagonists. Current eye research 20011101
Differential perturbation of neuronal and glial glutamate transport systems in retinal ischaemia. Neurochemistry international 20011001
Characteristics of L-aspartate transport and expression of EAAC-1 in sarcolemmal vesicles and isolated cells from rat heart. Cardiovascular research 20011001
Metabolic consequences of hyperhomocysteinemia in uremia. American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Physiological relevance of endogenous free D-serine in the mammalian brain: are scientists on a royal road for the treatment of glutamatergic-related brain disorders? Pathologie-biologie 20011001
D-Aspartate oxidase and D-amino acid oxidase are localised in the peroxisomes of terrestrial gastropods. European journal of cell biology 20011001
Determination of D- and L-aspartate in cell culturing medium, within cells of MPT1 cell line and in rat blood by a column-switching high-performance liquid chromatogrpahic method. Journal of chromatography. B, Biomedical sciences and applications 20010915
Synaptosomal and vesicular accumulation of L-glutamate, L-aspartate and D-aspartate. Neurochemistry international 20010901
Brain aging research at the close of the 20th century: from bench to bedside. Dialogues in clinical neuroscience 20010901
Effect of acute exposure to ammonia on glutamate transport in glial cells isolated from the salamander retina. Journal of neurophysiology 20010801
Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices. Pflugers Archiv : European journal of physiology 20010801
Differential effects of glutamate agonists and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats. Endocrine 20010801
D-Aspartate is stored in secretory granules and released through a Ca(2+)-dependent pathway in a subset of rat pheochromocytoma PC12 cells. The Journal of biological chemistry 20010713
Comparison of effects of DL-threo-beta-benzyloxyaspartate (DL-TBOA) and L-trans-pyrrolidine-2,4-dicarboxylate (t-2,4-PDC) on uptake and release of [3h]D-aspartate in astrocytes and glutamatergic neurons. Neurochemical research 20010601
Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain research 20010525
Regulation of mitochondrial glutamine/glutamate metabolism by glutamate transport: studies with (15)N. American journal of physiology. Cell physiology 20010501
A Na+-dependent electrogenic glutamate transporter current in voltage-clamped cells of corpora allata in the cricket Gryllus bimaculatus. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501
Altered expression of glutamate transporters under hypoxic conditions in vitro. Journal of neuroscience research 20010415
Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism. Neurochemistry international 20010401
Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices. Neurochemistry international 20010301
Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum. Biochemical and biophysical research communications 20010223
FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices. Brain research 20010216
Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: comparison with hypothermia. Anesthesiology 20010201
N-methyl D-aspartate receptor-mediated bidirectional control of extracellular signal-regulated kinase activity in cortical neuronal cultures. The Journal of biological chemistry 20010126
Localization, transport, and uptake of D-aspartate in the rat adrenal and pituitary glands. Archives of biochemistry and biophysics 20010115
Substrate translocation kinetics of excitatory amino acid carrier 1 probed with laser-pulse photolysis of a new photolabile precursor of D-aspartic acid. Biochemistry 20010109
Matrix metalloproteinases in lung biology. Respiratory research 20010101
Transport of D-aspartate in cerebellar granule cells under cell-damaging conditions. Proceedings of the Western Pharmacology Society 20010101
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. Journal of medicinal chemistry 19960802

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