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CAS No: 17766-28-8 Catalog No: AG0025GF MDL No:MFCD00044809
Title | Journal |
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1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity. | ChemMedChem 20110103 |
Complete experimental and theoretical proton and carbon nuclear magnetic resonance spectral assignments, molecular structure and conformational study of 1-cyclohexylpiperazine and 1-(4-pyridyl)piperazine. | Magnetic resonance in chemistry : MRC 20100101 |
Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28). | Journal of medicinal chemistry 20091210 |
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review. | Central nervous system agents in medicinal chemistry 20090901 |
Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors. | ChemMedChem 20090201 |
Preparation of 99mTc-nitrido asymmetrical heterocomplex with 4-(cyclohexylpiperazin-1-yl)-dithioformate and its biological evaluation as a potential myocardial imaging agent. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20071001 |
Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer. | Molecular cancer therapeutics 20060701 |
Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET. | The Journal of pharmacy and pharmacology 20051101 |
Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors. | Bioorganic & medicinal chemistry 20050601 |
New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of 'THIQ'. | Journal of medicinal chemistry 20040826 |
4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity. | Journal of medicinal chemistry 20040422 |
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