200,000+ products from a single source!
sales@angenechem.com
Home > Nitro Compounds > 17117-34-9
17117-34-9 | 3-Nitrobenzanthrone
CAS No: 17117-34-9 Catalog No: AG01E6VX MDL No:
Product Description
Catalog Number:
AG01E6VX
Chemical Name:
3-Nitrobenzanthrone
CAS Number:
17117-34-9
IUPAC Name:
3-nitrobenzo[b]phenalen-7-one
InChI:
InChI=1S/C17H9NO3/c19-17-12-5-2-1-4-10(12)11-8-9-15(18(20)21)13-6-3-7-14(17)16(11)13/h1-9H
InChI Key:
QAJOWHGESRCVLY-UHFFFAOYSA-N
UNII:
O4OJW7BC7W
Properties
Complexity:
457
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
275.058g/mol
Formal Charge:
0
Heavy Atom Count:
21
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
275.263g/mol
Monoisotopic Mass:
275.058g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
62.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.1
Literature
| Title | Journal |
|---|---|
| Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. | Archives of toxicology 20170101 |
| Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. | Toxicology in vitro : an international journal published in association with BIBRA 20150201 |
| Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments. | Environment international 20120901 |
| Development of a two-dimensional high-performance liquid chromatography system coupled with on-line reduction as a new efficient analytical method of 3-nitrobenzanthrone, a potential human carcinogen. | Journal of chromatography. A 20120831 |
| Carcinogenic 3-nitrobenzanthrone but not 2-nitrobenzanthrone is metabolised to an unusual mercapturic acid in rats. | Toxicology letters 20120205 |
| DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis. | Mutagenesis 20111101 |
| Theoretical investigations on the formation of nitrobenzanthrone-DNA adducts. | Organic & biomolecular chemistry 20110907 |
| Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats. | Mutation research 20110227 |
| Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone. | Chemical research in toxicology 20100719 |
| Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model. | The FEBS journal 20100601 |
| 3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells. | Mutation research 20100203 |
| Quantification of 3-nitrobenzanthrone-DNA adducts using online column-switching HPLC-electrospray tandem mass spectrometry. | Chemical research in toxicology 20091101 |
| The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin. | Cancer letters 20091018 |
| 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung. | Mutation research 20090531 |
| Accelerated (32)P-HPLC for bulky DNA adducts. | Mutagenesis 20090301 |
| The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences. | Mutagenesis 20090101 |
| Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 - similarity between human and rat enzymes. | Neuro endocrinology letters 20090101 |
| Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse. | Mutagenesis 20081101 |
| Tissue-specific metabolic activation and mutagenicity of 3-nitrobenzanthrone in MutaMouse. | Environmental and molecular mutagenesis 20081001 |
| Mutagenic potential of nitrenium ions of nitrobenzanthrones: correlation between theory and experiment. | Environmental and molecular mutagenesis 20081001 |
| Mutagenic specificity of N-acetoxy-3-aminobenzanthrone, a major metabolically activated form of 3-nitrobenzanthrone, in shuttle vector plasmids propagated in human cells. | Mutation research 20080630 |
| The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity. | Toxicology 20080502 |
| DNA adduct formation in human hepatoma cells treated with 3-nitrobenzanthrone: analysis by the (32)P-postlabeling method. | Mutation research 20071201 |
| Structural identification of DNA adducts derived from 3-nitrobenzanthrone, a potent carcinogen present in the atmosphere. | Chemistry, an Asian journal 20070903 |
| Mutagenicity and DNA adduct formation by the urban air pollutant 2-nitrobenzanthrone. | Toxicological sciences : an official journal of the Society of Toxicology 20070801 |
| The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells. | Toxicology and applied pharmacology 20070601 |
| Formation and persistence of DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in target and non-target organs after intratracheal instillation in rats. | Carcinogenesis 20070501 |
| DNA adduct formation and oxidative stress from the carcinogenic urban air pollutant 3-nitrobenzanthrone and its isomer 2-nitrobenzanthrone, in vitro and in vivo. | Mutagenesis 20070301 |
| Mutagenic activities and physicochemical properties of selected nitrobenzanthrones. | Mutagenesis 20061101 |
| The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase. | Drug metabolism and disposition: the biological fate of chemicals 20060801 |
| DNA damage and acute toxicity caused by the urban air pollutant 3-nitrobenzanthrone in rats: characterization of DNA adducts in eight different tissues and organs with synthesized standards. | Environmental and molecular mutagenesis 20060801 |
| Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine. | International journal of cancer 20060501 |
| Carcinogenic 3-nitrobenzanthrone induces oxidative damage to isolated and cellular DNA. | Free radical biology & medicine 20060401 |
| Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases. | Cancer letters 20060328 |
| Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201 |
| Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051115 |
| 3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence. | Mutagenesis 20051101 |
| DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone after intratracheal instillation in rats. | International journal of cancer 20051010 |
| DNA adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone. | Carcinogenesis 20051001 |
| Assessment of 3-nitrobenzanthrone reductase activity in mammalian tissues by normal-phase HPLC with fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925 |
| Synthesis, characterization, and 32p-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone. | Chemical research in toxicology 20050601 |
| Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols. | Cancer research 20050401 |
| 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2. | Chemical research in toxicology 20040801 |
| Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells. | Mutagenesis 20040301 |
| 3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells. | Toxicology letters 20040115 |
| DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse. | Environmental and molecular mutagenesis 20040101 |
| DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes. | Cancer letters 20031008 |
| Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells. | International journal of cancer 20030710 |
| Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan. | Mutation research 20030708 |
| Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase. | Cancer research 20030601 |
| Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection. | Journal of chromatography. A 20030411 |
| DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats. | Biochemical and biophysical research communications 20030103 |
| Determination of mutagenic 3-nitrobenzanthrone in diesel exhaust particulate matter by three-dimensional high-performance liquid chromatography. | The Analyst 20030101 |
| Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase. | Carcinogenesis 20021101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.