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17094-01-8 | Sepiapterin
CAS No: 17094-01-8 Catalog No: AG003U8N MDL No:MFCD00210214
Product Description
Catalog Number:
AG003U8N
Chemical Name:
Sepiapterin
CAS Number:
17094-01-8
MDL Number:
MFCD00210214
IUPAC Name:
2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-3H-pteridin-4-one
InChI:
InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17)/t3-/m0/s1
InChI Key:
VPVOXUSPXFPWBN-VKHMYHEASA-N
UNII:
CJQ26KO7HP
Properties
Complexity:
491
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
237.086g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
237.219g/mol
Monoisotopic Mass:
237.086g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
129A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2
Literature
| Title | Journal |
|---|---|
| Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms. | The FEBS journal 20140801 |
| 4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation. | Arteriosclerosis, thrombosis, and vascular biology 20071101 |
| Mechanisms of inducible nitric oxide synthase-mediated vascular dysfunction. | Arteriosclerosis, thrombosis, and vascular biology 20050801 |
| GTP cyclohydrolase 1 inhibition attenuates vasodilation and increases blood pressure in rats. | American journal of physiology. Heart and circulatory physiology 20031101 |
| Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. | Journal of cardiovascular pharmacology 20010301 |
| Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules. | Journal of the American Society of Nephrology : JASN 19950201 |
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