200,000+ products from a single source!
sales@angenechem.com
Home > Indoles and Oxindole > 1670-87-7
1670-87-7 | 1H-Indole-5-carboxamide
CAS No: 1670-87-7 Catalog No: AG003EEJ MDL No:MFCD07779486
Product Description
Catalog Number:
AG003EEJ
Chemical Name:
1H-Indole-5-carboxamide
CAS Number:
1670-87-7
Molecular Formula:
C9H8N2O
Molecular Weight:
160.1726
MDL Number:
MFCD07779486
IUPAC Name:
1H-indole-5-carboxamide
InChI:
InChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChI Key:
GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES:
NC(=O)c1ccc2c(c1)cc[nH]2
Properties
Complexity:
193
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
160.064g/mol
Formal Charge:
0
Heavy Atom Count:
12
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
160.176g/mol
Monoisotopic Mass:
160.064g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
58.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.9
Literature
| Title | Journal |
|---|---|
| p38a MAPK is involved in BMP-2-induced odontoblastic differentiation of human dental pulp cells. | International endodontic journal 20120301 |
| From benzimidazole to indole-5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase. Part 1: indole C-2 SAR and discovery of diamide derivatives with nanomolar potency in cell-based subgenomic replicons. | Bioorganic & medicinal chemistry letters 20110615 |
| Indole 5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase with nanomolar potency in cell-based subgenomic replicons (part 2): central amino acid linker and right-hand-side SAR studies. | Bioorganic & medicinal chemistry letters 20110615 |
| Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication. | Experimental parasitology 20110601 |
| P38alpha-selective mitogen-activated protein kinase inhibitor for improvement of cultured human islet recovery. | Pancreas 20100501 |
| Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma. | The European respiratory journal 20100401 |
| 3D-QSAR studies of arylcarboxamides with inhibitory activity on InhA using pharmacophore-based alignment. | Chemical biology & drug design 20100201 |
| Topical alpha-selective p38 MAP kinase inhibition reduces acute skin inflammation in guinea pig. | Journal of inflammation research 20100101 |
| p38 Mitogen-activated protein kinase inhibition reduces inflammatory cytokines in a brain-dead transplant donor animal model. | Heart, lung & circulation 20091201 |
| Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat. | Journal of neuroscience research 20090301 |
| p38 MAPK inhibition reduces diabetes-induced impairment of wound healing. | Diabetes, metabolic syndrome and obesity : targets and therapy 20090101 |
| Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation. | European journal of pharmacology 20081214 |
| Prevention of trabecular bone loss induced by estrogen deficiency by a selective p38alpha inhibitor. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080901 |
| p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation. | The Journal of pharmacology and experimental therapeutics 20080301 |
| Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinase. | Pharmacology 20080101 |
| A p38 mitogen-activated protein kinase inhibitor arrests active alveolar bone loss in a rat periodontitis model. | Journal of periodontology 20071001 |
| Improvement of human islet cryopreservation by a p38 MAPK inhibitor. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070501 |
| Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance. | Cancer research 20070501 |
| A p38alpha selective mitogen-activated protein kinase inhibitor prevents periodontal bone loss. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Selective inhibition of p38alpha MAPK improves cardiac function and reduces myocardial apoptosis in rat model of myocardial injury. | American journal of physiology. Heart and circulatory physiology 20061001 |
| Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages. | British journal of pharmacology 20061001 |
| Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness. | European journal of pharmacology 20060821 |
| A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis. | The Journal of pharmacology and experimental therapeutics 20060701 |
| Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes. | The Journal of pharmacology and experimental therapeutics 20060701 |
| Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses. | Cancer research 20060701 |
| Peripheral and central p38 MAPK mediates capsaicin-induced hyperalgesia. | Pain 20041001 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus. | Bioorganic & medicinal chemistry letters 20010709 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.