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1668-10-6 | Acetamide, 2-amino-, hydrochloride (1:1)
CAS No: 1668-10-6 Catalog No: AG001WYR MDL No:MFCD00013008
Product Description
Catalog Number:
AG001WYR
Chemical Name:
Acetamide, 2-amino-, hydrochloride (1:1)
CAS Number:
1668-10-6
Molecular Formula:
C2H7ClN2O
Molecular Weight:
110.5428
MDL Number:
MFCD00013008
IUPAC Name:
2-aminoacetamide;hydrochloride
InChI:
InChI=1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
InChI Key:
WKNMKGVLOWGGOU-UHFFFAOYSA-N
SMILES:
NCC(=O)N.Cl
EC Number:
216-789-1
NSC Number:
9225
Properties
Complexity:
42.9
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
110.025g/mol
Formal Charge:
0
Heavy Atom Count:
6
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
110.541g/mol
Monoisotopic Mass:
110.025g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
69.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| HCV NS5A replication complex inhibitors. Part 5: discovery of potent and pan-genotypic glycinamide cap derivatives. | Bioorganic & medicinal chemistry letters 20130801 |
| Acylglycinamides as inhibitors of glycine transporter type 1. | Bioorganic & medicinal chemistry letters 20111015 |
| N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists. | Bioorganic & medicinal chemistry letters 20110915 |
| Glycine amide shielding on the aromatic surfaces of lysozyme: implication for suppression of protein aggregation. | FEBS letters 20110204 |
| [Design, synthesis and in vitro activity of glycinamide-bearing compounds as DPP-IV inhibitors]. | Yao xue xue bao = Acta pharmaceutica Sinica 20101101 |
| Well-defined synthetic polymers with a protein-like gelation behavior in water. | Chemical communications (Cambridge, England) 20100707 |
| Glycine amides as PPARalpha agonists. | Bioorganic & medicinal chemistry letters 20100601 |
| gamma-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists. | Bioorganic & medicinal chemistry letters 20100415 |
| Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. | Nature chemical biology 20090101 |
| Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology. | Retrovirology 20090101 |
| Activity of the small modified amino acid alpha-hydroxy glycineamide on in vitro and in vivo human immunodeficiency virus type 1 capsid assembly and infectivity. | Antimicrobial agents and chemotherapy 20081001 |
| Rapid cleavage of unactivated, unstrained amide bonds at neutral pH. | The Journal of organic chemistry 20080815 |
| Investigation of anion retention and cation exclusion effects for several C18 stationary phases. | Analytical chemistry 20070715 |
| Computational study of urea and its homologue glycinamide: conformations, rotational barriers, and relative interactions with sodium chloride. | Langmuir : the ACS journal of surfaces and colloids 20070508 |
| The rate enhancement produced by the ribosome: an improved model. | Biochemistry 20070403 |
| Preparation of guanine and diaminopurine from biuret. Part III. | Chemistry & biodiversity 20070401 |
| Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity. | The journal of pain : official journal of the American Pain Society 20061001 |
| Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists. | Bioorganic & medicinal chemistry letters 20060715 |
| Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins. | Bioconjugate chemistry 20060101 |
| [New biological active derivatives of indomethacin and acetylsalicylic acid. Synthesis, physico-chemical characterisation and structure validation]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101 |
| Synthesis of (-)-quinocarcin by directed condensation of alpha-amino aldehydes. | Journal of the American Chemical Society 20051207 |
| Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds. | Journal of medicinal chemistry 20051201 |
| Kinetic investigation of the effect of the amino acid side chains in the selective acidolysis of N-acyl-N,alpha,alpha-trialkyl glycine amides. | Journal of peptide science : an official publication of the European Peptide Society 20051001 |
| Kinetic and mechanistic investigation of the selective acidolysis of the C-terminal amide bond of N-acyl-N,alpha,alpha-trialkyl glycine amides. | Journal of peptide science : an official publication of the European Peptide Society 20050701 |
| A potential prebiotic route to adenine from hypoxanthine. | Chemistry & biodiversity 20050701 |
| Application of intramolecular 1,3-dipolar cyclic addition of azide and olefin; construction of (pyrrolidine-2-ylidene)glycinate and glycinamides. | Chemical & pharmaceutical bulletin 20050501 |
| Double proton transfer and one-electron oxidation behavior in double H-bonded glycinamide-glycine complex in the gas phase. | Journal of computational chemistry 20050430 |
| Highly enantioselective phase-transfer-catalyzed alkylation of protected alpha-amino acid amides toward practical asymmetric synthesis of vicinal diamines, alpha-amino ketones, and alpha-amino alcohols. | Journal of the American Chemical Society 20050413 |
| Theoretical study of the effect of water in the process of proton transfer of glycinamide. | The journal of physical chemistry. B 20050331 |
| Chiral ion-exchange capillary electrochromatography of arylglycine amides with dextran sulfate as a pseudostationary phase. | Electrophoresis 20050201 |
| Specific inhibition and stabilization of aspergilloglutamic peptidase by the propeptide. Identification of critical sequences and residues in the propeptide. | The Journal of biological chemistry 20050114 |
| Glycine-amide is an active metabolite of the antiretroviral tripeptide glycyl-prolyl-glycine-amide. | Antimicrobial agents and chemotherapy 20050101 |
| Highly stereoselective Michael addition reactions of CamTHP*-desymmetrized glycinamide for the synthesis of functionally dense amino acid derivatives. | Organic letters 20041125 |
| Double proton transfer behavior and one-electron oxidation effect in double H-bonded glycinamide-formic acid complex. | The Journal of chemical physics 20041122 |
| Construction, characterization, and use of small-insert gene banks of DNA isolated from soil and enrichment cultures for the recovery of novel amidases. | Environmental microbiology 20040901 |
| BMS-201620: a selective beta 3 agonist. | Bioorganic & medicinal chemistry letters 20040705 |
| Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose? | Human immunology 20040501 |
| One-step synthesis of hypoxanthine from glycinamide and diformylurea. | Chemistry & biodiversity 20040101 |
| Biochemical and structural characterization of the cross-linked complex of nitrogenase: comparison to the ADP-AlF4(-)-stabilized structure. | Biochemistry 20021231 |
| New 2H-tetrahydro-1, 3, 5-thiadiazine-2-thiones incorporating glycine and glycinamide as potential antifungal agents. | Archiv der Pharmazie 20021101 |
| Synthetic Cu(II) and Ni(II) peptidases. | Metal ions in biological systems 20010101 |
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