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CAS No: 16450-41-2 Catalog No: AG001UX2 MDL No:
Title | Journal |
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Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase. | Journal of medicinal chemistry 20111027 |
Nicotine stimulation of the medulla increases blood flow of the common carotid artery in cats. | Autonomic neuroscience : basic & clinical 20100115 |
The internal state of medium spiny neurons varies in response to different input signals. | BMC systems biology 20100101 |
Glutamate release upon purinergic action in the dorsal facial area of the medulla increases blood flow in the common carotid artery in cats. | Neuroscience 20091020 |
Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. | Journal of medicinal chemistry 20090813 |
Synthesis and evaluation of novel organogermanium sesquioxides as antitumor agents. | Bioinorganic chemistry and applications 20090101 |
Nitric oxide and glutamate in the dorsal facial area regulate common carotid blood flow in the cat. | European journal of pharmacology 20081010 |
Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates. | Journal of medicinal chemistry 20080925 |
[Synthesis of diethyl N-[p-(methylamino)benzoyl]-L-glutamate]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20080818 |
Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester. | Biochimica et biophysica acta 20080601 |
Alcohol related changes in regulation of NMDA receptor functions. | Current neuropharmacology 20080301 |
Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors. | Journal of medicinal chemistry 20080110 |
Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: evaluation of in vitro anti-cancer and anti-folate activities. | European journal of medicinal chemistry 20080101 |
Synthesis of (-)-Indolizidine 167B based on domino hydroformylation/cyclization reactions. | Beilstein journal of organic chemistry 20080101 |
Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates. | Journal of medicinal chemistry 20070628 |
The blockade of AMPA-kainate and NMDA receptors in the dorsal periaqueductal gray reduces the effects of diazepam withdrawal in rats. | Pharmacology, biochemistry, and behavior 20070101 |
Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates. | Bioorganic & medicinal chemistry 20061215 |
DARPP-32 is a robust integrator of dopamine and glutamate signals. | PLoS computational biology 20061201 |
Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1). | Journal of medicinal chemistry 20060209 |
Activation by N-acetyl-L-aspartate of acutely dissociated hippocampal neurons in rats via metabotropic glutamate receptors. | Epilepsia 20030901 |
Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol. | Life sciences 20021108 |
Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat. | Autonomic neuroscience : basic & clinical 20021031 |
Mouse cerebellar adenosine-glutamate interactions and modulation of ethanol-induced motor incoordination. | Alcoholism, clinical and experimental research 20020901 |
Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolate. | Journal of medicinal chemistry 20020425 |
Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester. | Biomacromolecules 20020101 |
[The role of non-NMDA glutamate receptors in the EEG effects of chronic administration of noopept GVS-111 in awake rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20020101 |
Primary neurotransmitters and regulatory substances onto vestibular nucleus neurons. | Uchu Seibutsu Kagaku 20011201 |
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat. | American journal of physiology. Regulatory, integrative and comparative physiology 20011101 |
Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation. | Japanese journal of pharmacology 20010801 |
beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. | Journal of neurophysiology 20010301 |
[Rheologic infusion therapy, neurotransmitter administration and lidocaine injection in tinnitus. A staged therapeutic concept]. | HNO 20010201 |
NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance. | The European journal of neuroscience 20010101 |
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists. | Annals of the New York Academy of Sciences 19920511 |
Glutamate receptor antagonists block cocaine-induced convulsions and death. | Brain research bulletin 19911101 |
Glutamate antagonists prevent morphine withdrawal in mice and guinea pigs. | Neuroscience letters 19910128 |
Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats. | Neuroscience letters 19890828 |
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