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163222-33-1

163222-33-1 | 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-

CAS No: 163222-33-1 Catalog No: AG001TWG MDL No:MFCD00937872

Product Description

Catalog Number:
AG001TWG
Chemical Name:
2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-
CAS Number:
163222-33-1
Molecular Formula:
C24H21F2NO3
Molecular Weight:
409.4252
MDL Number:
MFCD00937872
SMILES:
Oc1ccc(cc1)[C@@H]1[C@@H](CC[C@@H](c2ccc(cc2)F)O)C(=O)N1c1ccc(cc1)F

Literature

Title Journal
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Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease. Journal of the American College of Cardiology 20110830
Learning to walk before we run: the mechanics of medical intervention for peripheral arterial disease. Journal of the American College of Cardiology 20110830
A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction. The Journal of organic chemistry 20110819
Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study). The American journal of cardiology 20110815
Differences in cardiovascular risk profile between electrocardiographic hypertrophy versus strain in asymptomatic patients with aortic stenosis (from SEAS data). The American journal of cardiology 20110815
Do functional foods have a role in the prevention of cardiovascular disease? Circulation 20110802
Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans. Circulation 20110802
Impact of hypertriglyceridemia on endothelial dysfunction during statin ± ezetimibe therapy in patients with coronary heart disease. The American journal of cardiology 20110801
Ezetimibe combined with simvastatin compared with simvastatin alone results in a greater suppression of oxidative stress and enhanced fibrinolysis in patients after acute coronary events. Journal of cardiovascular pharmacology 20110801
Ezetimibe improves postprandial hyperlipemia and its induced endothelial dysfunction. Atherosclerosis 20110801
The ezetimibe controversy: implications for clinical practice. Therapeutic advances in cardiovascular disease 20110801
Begin with the real-world patients of non-goal-achieved hypercholesterolemia in taiwan through the ezetimibe/simvastatin tablet - The BRAVO Study. Current medical research and opinion 20110801
Where does the interplay between cholesterol absorption and synthesis in the context of statin and/or ezetimibe treatment stand today? Atherosclerosis 20110801
Opening a new lipid 'apo-thecary': incorporating apolipoproteins as potential risk factors and treatment targets to reduce cardiovascular risk. Mayo Clinic proceedings 20110801
[The efficacy of ezetimibe on nonalcoholic fatty liver disease (NAFLD)]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20110801
Why, when and how should hypertriglyceridemia be treated in the high-risk cardiovascular patient? Expert review of cardiovascular therapy 20110801
Retrospective study on antihyperlipidemic efficacy and safety of simvastatin, ezetimibe and their combination in Korean adults. Archives of pharmacal research 20110801
Trial clouds use of niacin with a statin. Harvard heart letter : from Harvard Medical School 20110801
Managing dyslipidaemia: evolving role of combination therapy. Journal of the Indian Medical Association 20110801
What is the degradation product of ezetimibe? Journal of pharmaceutical and biomedical analysis 20110715
Effect of lipid-lowering treatment on natural history of heterozygous familial hypercholesterolemia in past three decades. The American journal of cardiology 20110715
Lipid-altering efficacy and safety profile of combination therapy with ezetimibe/statin vs. statin monotherapy in patients with and without diabetes: an analysis of pooled data from 27 clinical trials. Diabetes, obesity & metabolism 20110701
Ambient air pollution and lipoprotein-associated phospholipase A₂ in survivors of myocardial infarction. Environmental health perspectives 20110701
Statin myopathy: significant problem with minimal awareness by clinicians and no emphasis by clinical investigators. Angiology 20110701
Ezetimibe beneficially influences fasting and postprandial triglyceride-rich lipoproteins in type 2 diabetes. Atherosclerosis 20110701
SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin. American journal of physiology. Gastrointestinal and liver physiology 20110701
Carotid intima-media thickness and ezetimibe: the end of a misunderstanding? Current vascular pharmacology 20110701
Topical anti-inflammatory effect of hypocholesterolaemic drugs. The Journal of pharmacy and pharmacology 20110701
Comparison of effects of morning versus evening administration of ezetimibe/simvastatin on serum cholesterol in patients with primary hypercholesterolemia. The Annals of pharmacotherapy 20110701
[Pharmaco-economic optimization of cholesterol-lowering treatment with statins]. Medicina clinica 20110625
SHARP: a stab in the right direction in chronic kidney disease. Lancet (London, England) 20110625
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet (London, England) 20110609
Reimbursement of pharmaceuticals: reference pricing versus health technology assessment. The European journal of health economics : HEPAC : health economics in prevention and care 20110601
Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice. Cardiovascular research 20110601
Switching from statin monotherapy to ezetimibe/simvastatin or rosuvastatin modifies the relationships between apolipoprotein B, LDL cholesterol, and non-HDL cholesterol in patients at high risk of coronary disease. Clinical biochemistry 20110601
Comparison of the effects of combination atorvastatin (40 mg) + ezetimibe (10 mg) versus atorvastatin (40 mg) alone on secretory phospholipase A2 activity in patients with stable coronary artery disease or coronary artery disease equivalent. The American journal of cardiology 20110601
Utility of atherosclerosis imaging in the evaluation of high-density lipoprotein-raising therapies. Current atherosclerosis reports 20110601
Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis. Current medical research and opinion 20110601
[Efficacy and safety of ezetimibe in vascular risk units]. Revista clinica espanola 20110601
Hepatic Niemann-Pick C1-like 1. Current opinion in lipidology 20110601
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. European heart journal 20110601
Time-dependent impact of diabetes on mortality in patients after major lower extremity amputation: survival in a population-based 5-year cohort in Germany. Diabetes care 20110601
Clinical aspects of PCSK9. Atherosclerosis 20110601
Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia. International angiology : a journal of the International Union of Angiology 20110601
Half-dose ezetimibe add-on to statin therapy is effective in improving resistant hyperlipidaemia in Asian patients with ischaemic heart disease. Singapore medical journal 20110601
Lipid lowering therapy in type 2 diabetes. Wiener medizinische Wochenschrift (1946) 20110601
Therapeutic target achievement in type 2 diabetic patients after hyperglycemia, hypertension, dyslipidemia management. Diabetes & metabolism journal 20110601
[After bypass surgery nearly all lipids are in the normal range. However, Lp(a) is too high, what can be done?]. MMW Fortschritte der Medizin 20110526
More on DSMBs. The New England journal of medicine 20110512
Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet. Metabolism: clinical and experimental 20110501
Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects. European journal of clinical pharmacology 20110501
Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters. Molecular nutrition & food research 20110501
Statin-induced myopathy: a review and update. Expert opinion on drug safety 20110501
Adherence to single-pill combination versus multiple-pill combination lipid-modifying therapy among patients with mixed dyslipidemia in a managed care population. Current medical research and opinion 20110501
Safety review of combination drugs for hyperlipidemia. Expert opinion on drug safety 20110501
Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients. Korean circulation journal 20110501
Isolation and structure elucidation of major alkaline degradant of ezetimibe. Journal of pharmaceutical and biomedical analysis 20110428
Effects of coadministered ezetimibe plus fenofibrate in mixed dyslipidemic patients with metabolic syndrome. Metabolic syndrome and related disorders 20110401
Statin therapy and cataract in type 2 diabetes. Diabetes & metabolism 20110401
Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9. Journal of lipid research 20110401
The effect of ezetimibe and simvastatin on monocyte cytokine release in patients with isolated hypercholesterolemia. Journal of cardiovascular pharmacology 20110401
Ezetimibe treatment lowers indicators of oxidative stress in hypercholesterolemic subjects with high oxidative stress. Lipids 20110401
Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers. Clinical pharmacology and therapeutics 20110401
Chronic administration of ezetimibe increases active glucagon-like peptide-1 and improves glycemic control and pancreatic beta cell mass in a rat model of type 2 diabetes. Biochemical and biophysical research communications 20110401
Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers. The Journal of antimicrobial chemotherapy 20110401
Effects of ezetimibe on atherosclerosis in preclinical models. Atherosclerosis 20110401
Statin/ezetimibe combination therapy: emerging evidence. Current opinion in lipidology 20110401
Effectiveness of drug-eluting stents versus bare-metal stents in large coronary arteries in patients with acute myocardial infarction. Journal of Korean medical science 20110401
Medical management of stable coronary artery disease. American family physician 20110401
Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes. Diabetes & vascular disease research 20110401
Achieving optimal lipid goals in patients with coronary artery disease. The American journal of cardiology 20110315
Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease. The international journal of cardiovascular imaging 20110301
Induction of microsomal triglyceride transfer protein expression is a candidate mechanism by which ezetimibe therapy might exert beneficial effects in patients with nonalcoholic steatohepatitis. Journal of gastroenterology 20110301
Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients. Journal of vascular surgery 20110301
Role of statins in preventing adverse cardiovascular outcomes in patients with chronic kidney disease. Current opinion in nephrology and hypertension 20110301
The effect of simvastatin alone versus simvastatin plus ezetimibe on the concentration of small dense low-density lipoprotein cholesterol in subjects with primary hypercholesterolemia. Current medical research and opinion 20110301
Ezetimibe and low density lipoprotein subfractions: an ongoing debate. Current medical research and opinion 20110301
Lipid modification in the elderly using the combination of a statin and a cholesterol absorption inhibitor. Expert opinion on pharmacotherapy 20110301
Outcome of patients with low-gradient 'severe' aortic stenosis and preserved ejection fraction. Circulation 20110301
Impaired kidney allograft function following ezetimibe therapy. Iranian journal of kidney diseases 20110301
The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol Rationale and study design. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes (AIM-HIGH). American heart journal 20110301
The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol: baseline characteristics of study participants. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: impact on Global Health outcomes (AIM-HIGH) trial. American heart journal 20110301
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS biology 20110301
Combinations of ezetimibe with nonstatin drug regimens affecting lipid metabolism. Expert review of cardiovascular therapy 20110301
Depressogenic effects of medications: a review. Dialogues in clinical neuroscience 20110301
Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk. Korean circulation journal 20110301
Perceived barriers to application of glycaemic index: valid concerns or lost in translation? Nutrients 20110301
The comparative efficacy of ezetimibe added to atorvastatin 10 mg versus uptitration to atorvastatin 40 mg in subgroups of patients aged 65 to 74 years or greater than or equal to 75 years. Journal of geriatric cardiology : JGC 20110301
Experimental, SOPPA(CCSD), and DFT analysis of substitutent effects on NMR 1JCF coupling constants in fluorobenzene derivatives. The journal of physical chemistry. A 20110224
Ezetimibe, an inhibitor of intestinal cholesterol absorption, decreases serum level of malondialdehyde-modified low-density lipoprotein in patients with hypercholesterolemia. International journal of cardiology 20110203
Enhanced spectrophotometric determination of two antihyperlipidemic mixtures containing ezetimibe in pharmaceutical preparations. Drug testing and analysis 20110201
Human NPC1L1 expression is positively regulated by PPARα. Pharmaceutical research 20110201
What combination therapy with a statin, if any, would you recommend? Current atherosclerosis reports 20110201
The anti-ischemic and anti-anginal properties of statins. Current atherosclerosis reports 20110201
Achievement of lipid targets with the combination of rosuvastatin and fenofibric Acid in patients with type 2 diabetes mellitus. Cardiovascular drugs and therapy 20110201
Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection. Current atherosclerosis reports 20110201
Therapies targeting exogenous cholesterol uptake: new insights and controversies. Current atherosclerosis reports 20110201
Comparison of fibrate, ezetimibe, low- and high-dose statin therapy for the dyslipidemia of the metabolic syndrome in a mouse model. Angiology 20110201
Ezetimibe is effective in the treatment of persistent hyperlipidemia of renal allograft recipients. Clinical nephrology 20110201
Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011? Complementary therapies in medicine 20110201
The effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂. Clinical cardiology 20110201
Combination of prescribing restrictions and policies to engineer low prices to reduce reimbursement costs. Expert review of pharmacoeconomics & outcomes research 20110201
Efficacy of ezetimibe as monotherapy or combination therapy in hypercholesterolemic patients with and without diabetes. The journal of medical investigation : JMI 20110201
Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: An analysis of 65,396 hospitalizations from 344 hospita participating in Get With The Guidelines (GWTG). American heart journal 20110201
Phytosterols and phytosterolemia: gene-diet interactions. Genes & nutrition 20110201
Lipid-lowering effects of ezetimibe and simvastatin in combination. Expert review of cardiovascular therapy 20110201
Combination therapy with ezetimibe/simvastatin versus statin monotherapy for low-density lipoprotein cholesterol reduction and goal attainment in a real-world clinical setting. Clinical therapeutics 20110201
Statin-associated myasthenic weakness. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110201
Response: a retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients (korean diabetes j 2010;34:359-67). Diabetes & metabolism journal 20110201
Economic evaluation of ezetimibe combined with simvastatin for the treatment of primary hypercholesterolaemia. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110201
Ezetimibe, cardiovascular risk and atherogenic dyslipidaemia. Archives of medical science : AMS 20110201
Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment. International journal of pharmaceutics 20110117
Managing residual risk in patients receiving statin therapy. The Medical journal of Australia 20110103
Managing residual risk in patients receiving statin therapy. Comment. The Medical journal of Australia 20110103
Ethanol extract of fructus schisandrae decreases hepatic triglyceride level in mice fed with a high fat/cholesterol diet, with attention to acute toxicity. Evidence-based complementary and alternative medicine : eCAM 20110101
Dyslipidaemia in the metabolic syndrome and type 2 diabetes: pathogenesis, priorities, pharmacotherapies. Expert opinion on pharmacotherapy 20110101
Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease. Journal of gastroenterology 20110101
Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport. Annual review of physiology 20110101
Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. European journal of clinical pharmacology 20110101
Refsum's Disease-Use of the Intestinal Lipase Inhibitor, Orlistat, as a Novel Therapeutic Approach to a Complex Disorder. Journal of obesity 20110101
A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101
Comments regarding 'A randomised placebo-controlled double-blind trial to evaluate lipid-lowering pharmacotherapy on proteolysis and inflammation in abdominal aortic aneurysms'. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101
Ezetimibe and vascular inflammation. Current vascular pharmacology 20110101
Ezetimibe and reactive oxygen species. Current vascular pharmacology 20110101
Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment. Current vascular pharmacology 20110101
Ezetimibe and vascular endothelial function. Current vascular pharmacology 20110101
New concept of vascular calcification and metabolism. Current vascular pharmacology 20110101
Ezetimibe; more than a low density lipoprotein cholesterol lowering drug? An update after 4 years. Current vascular pharmacology 20110101
Vascular protective effects of ezetimibe: seeking new therapeutic possibilities of ezetimibe in vascular disease. Current vascular pharmacology 20110101
Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine. American journal of physiology. Gastrointestinal and liver physiology 20110101
Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination. Journal of biomedicine & biotechnology 20110101
'Trig-onometry': non-high-density lipoprotein cholesterol as a therapeutic target in dyslipidaemia. International journal of clinical practice 20110101
Adjunctive lipid lowering therapy in the era of surrogate endpoints. Cardiology in review 20110101
Standards of medical care in diabetes--2011. Diabetes care 20110101
Design and characterization of nanocrystal formulations containing ezetimibe. Chemical & pharmaceutical bulletin 20110101
Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study. Lipids in health and disease 20110101
Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties. Cardiovascular diabetology 20110101
Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study. Cardiovascular ultrasound 20110101
Comparative study between high-dose fluvastatin and low-dose fluvastatin and ezetimibe with regard to the effect on endothelial function in diabetic patients. Endocrine journal 20110101
Cardiorenal syndrome type 4-cardiovascular disease in patients with chronic kidney disease: epidemiology, pathogenesis, and management. International journal of nephrology 20110101
Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits. Vascular health and risk management 20110101
Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents. Lipids in health and disease 20110101
An essential role for diet in exercise-mediated protection against dyslipidemia, inflammation and atherosclerosis in ApoE⁻/⁻ mice. PloS one 20110101
Subjects with molecularly defined familial hypercholesterolemia or familial defective apoB-100 are not being adequately treated. PloS one 20110101
Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice. Journal of inflammation (London, England) 20110101
ABCA1 and ABCG1 expressions are regulated by statins and ezetimibe in Caco-2 cells. Drug metabolism and drug interactions 20110101
Persistent lipid abnormalities in patients treated with statins: Portuguese results of the Dyslipidemia International Study (DYSIS). Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20110101
Understanding hypertriglyceridemia in women: clinical impact and management with prescription omega-3-acid ethyl esters. International journal of women's health 20110101
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Use of a treatment optimization algorithm involving statin-ezetimibe combination aids in achievement of guideline-based low-density lipoprotein targets in patients with dyslipidemia at high vascular risk Guideline-based Undertaking to Improve Dyslipidemia Management in Canada (GUIDANC). The Canadian journal of cardiology 20110101
Identification of common differentially expressed genes in urinary bladder cancer. PloS one 20110101
Influence of polymorphisms and cholesterol-lowering treatment on SCARB1 mRNA expression. Journal of atherosclerosis and thrombosis 20110101
The structure of the NPC1L1 N-terminal domain in a closed conformation. PloS one 20110101
Solid self-nanoemulsifying cyclosporin A pellets prepared by fluid-bed coating: preparation, characterization and in vitro redispersibility. International journal of nanomedicine 20110101
Influence of simvastatin, fenofibrate and/or ezetimibe on correlation of low-density lipoprotein and nonhigh-density lipoprotein cholesterol with apolipoprotein B in mixed dyslipidemic patients. Journal of clinical lipidology 20110101
A validated densitometric method for analysis of atorvastatin calcium and metoprolol tartarate as bulk drugs and in combined capsule dosage forms. Journal of young pharmacists : JYP 20110101
Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography. Scientia pharmaceutica 20110101
Dyslipidemia associated with chronic kidney disease. The open cardiovascular medicine journal 20110101
Prosthetic aortic valve stenosis in end-stage renal failure. International journal of nephrology 20110101
Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment. The open cardiovascular medicine journal 20110101
Pharmacological management of cardiorenal syndromes. International journal of nephrology 20110101
Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART). Lipids in health and disease 20110101
Effective therapy using voglibose for nonalcoholic steatohepatitis in a patient with insufficient dietary and exercise therapy: exploring other treatment possibilities. Case reports in gastroenterology 20110101
Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma. Chemistry Central journal 20110101
Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation. Journal of lipids 20110101
Treating statin-intolerant patients. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment. Journal of clinical lipidology 20110101
Concordance between plasma apolipoprotein B levels and cholesterol indices among patients receiving statins and nonstatin treatment: Post-hoc analyses from the U.K. InPractice study. Journal of clinical lipidology 20110101
The role of statins in chronic kidney disease. American journal of nephrology 20110101
Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey. Drug design, development and therapy 20110101
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy. Nutrition journal 20110101
Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101
Clinical usefulness of additional treatment with ezetimibe in patients with coronary artery disease on statin therapy. - From the viewpoint of cholesterol metabolism.-. Circulation journal : official journal of the Japanese Circulation Society 20110101
Animal models of calcific aortic valve disease. International journal of inflammation 20110101
Alopecia areata: a new treatment plan. Clinical, cosmetic and investigational dermatology 20110101
Benefit and tolerability of the coadministration of ezetimibe and atorvastatin in acute coronary syndrome patients. Le Journal medical libanais. The Lebanese medical journal 20110101
A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis. BMC systems biology 20110101
Comparative efficacy of ezetimibe/simvastatin, rosuvastatin, and atorvastatin in uncontrolled hyperlipidemia patients. The American journal of managed care 20110101
Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients. Lipids in health and disease 20110101
Where are we heading with noninvasive clinical vascular physiology? Why and how should we assess endothelial function? Cardiology research and practice 20110101
Safe use of ezetimibe plus simvastatin in high-risk vascular patients (with chronic kidney disease and PAD). Cardiovascular journal of Africa 20110101
Lipid-lowering therapy: who can benefit? Vascular health and risk management 20110101
Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study. BMC nephrology 20110101
Short-term effect of fenofibrate on C-reactive protein: A meta-analysis of randomized controlled trials. Diabetology & metabolic syndrome 20110101
Exposure to statins and risk of common cancers: a series of nested case-control studies. BMC cancer 20110101
Ezetimibe in sirolimus-associated hyperlipidemia: to add or not to add to statins? Annals of transplantation 20110101
A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control. BMC cardiovascular disorders 20110101
Ethnic differences in the prevalence of polymorphisms in CYP7A1, CYP7B1 AND CYP27A1 enzymes involved in cholesterol metabolism. Journal of pharmacy & bioallied sciences 20110101
Prevalence, Predictors, and Impact of Low High-Density Lipoprotein Cholesterol on in-Hospital Outcomes Among Acute Coronary Syndrome Patients in the Middle East. The open cardiovascular medicine journal 20110101
Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations. Chemistry Central journal 20110101
Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model. Advances in preventive medicine 20110101
Homozygous familial hypercholesterolemia: case report of a rare cause of dyslipidemia. Pediatric endocrinology, diabetes, and metabolism 20110101
Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress. Journal of atherosclerosis and thrombosis 20110101
Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parameters. Clinical Medicine Insights. Cardiology 20110101
Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin. Lipids in health and disease 20110101
A case report and brief review of the literature on bilateral retinal infarction following cardiopulmonary bypass for coronary artery bypass grafting. Journal of cardiothoracic surgery 20110101
Achievement of specified low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol apolipoprotein B, and high-sensitivity C-reactive protein levels with ezetimibe/simvastatin or atorvastatin in metabolic syndrome patients with and without atherosclerotic vascular disease (from the VYMET study). Journal of clinical lipidology 20110101
Astragalus polysaccharides lowers plasma cholesterol through mechanisms distinct from statins. PloS one 20110101
Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials. BMJ (Clinical research ed.) 20110101
Development and Validation of a Reversed-phase HPLC Method for Simultaneous Determination of Aspirin, Atorvastatin Calcium and Clopidogrel Bisulphate in Capsules. Indian journal of pharmaceutical sciences 20110101
RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. PloS one 20110101
Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease. PloS one 20110101
Mild and moderate pre-dialysis chronic kidney disease is associated with increased coronary artery calcium. Vascular health and risk management 20110101
Influence of ezetimibe monotherapy on ischemia-modified albumin levels in hypercholesterolemic patients. Pharmacological reports : PR 20110101
Diffuse involvement of aorta in patient with familial hyperlipidemia. ISRN cardiology 20110101
Ezetimibe--a new approach in hypercholesterolemia management. Pharmacological reports : PR 20110101
Ezetimibe. Profiles of drug substances, excipients, and related methodology 20110101
Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors. Frontiers in endocrinology 20110101
Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica. Evidence-based complementary and alternative medicine : eCAM 20101201
Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells. Digestive diseases and sciences 20101201
Effect of ezetimibe-simvastatine over endothelial dysfunction in dyslipidemic patients: assessment by 13N-ammonia positron emission tomography. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20101201
Attainment of Canadian and European guidelines' lipid targets with atorvastatin plus ezetimibe vs. doubling the dose of atorvastatin. International journal of clinical practice 20101201
Lipoprotein(a) as a cardiovascular risk factor: current status. European heart journal 20101201
2-Azetidinone--a new profile of various pharmacological activities. European journal of medicinal chemistry 20101201
Spiroimidazolidinone NPC1L1 inhibitors. Part 2: structure-activity studies and in vivo efficacy. Bioorganic & medicinal chemistry letters 20101201
Lipid lowering for secondary prevention of cardiovascular disease in older adults. Drugs & aging 20101201
Impact of baseline severity of aortic valve stenosis on effect of intensive lipid lowering therapy (from the SEAS study). The American journal of cardiology 20101201
Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: an analysis of 65,396 hospitalizations from 344 hospitals participating in Get With The Guidelines (GWTG). American heart journal 20101201
Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia. International angiology : a journal of the International Union of Angiology 20101201
Lack of clinically relevant drug-drug interactions when dalcetrapib is co-administered with ezetimibe. British journal of clinical pharmacology 20101201
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20101201
A retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients. Korean diabetes journal 20101201
Effects of statins on the epicardial fat thickness in patients with coronary artery stenosis underwent percutaneous coronary intervention: comparison of atorvastatin with simvastatin/ezetimibe. Journal of cardiovascular ultrasound 20101201
Effect of atorvastatin in patients with chronic heart failure - insights from randomized clinical trials. Archives of medical science : AMS 20101201
Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia. Human molecular genetics 20101115
Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial. Lancet (London, England) 20101113
The fatty acid composition of plasma cholesteryl esters and estimated desaturase activities in patients with nonalcoholic fatty liver disease and the effect of long-term ezetimibe therapy on these levels. Clinica chimica acta; international journal of clinical chemistry 20101111
Effect of non-statin lipid lowering and anti-obesity drugs on LDL subfractions in patients with mixed dyslipidaemia. Current vascular pharmacology 20101101
Effects of lipid-lowering drugs on adiponectin. Current vascular pharmacology 20101101
Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany. Clinical research in cardiology : official journal of the German Cardiac Society 20101101
Effect of ezetimibe on incretin secretion in response to the intestinal absorption of a mixed meal. American journal of physiology. Gastrointestinal and liver physiology 20101101
Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis. Journal of lipid research 20101101
Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1. American journal of physiology. Gastrointestinal and liver physiology 20101101
Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice. Arteriosclerosis, thrombosis, and vascular biology 20101101
Potential therapeutic uses for ezetimibe beyond lowering LDL-c to decrease cardiovascular events. Diabetes, obesity & metabolism 20101101
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Quantitative analysis of the cholesterol-lowering drugs ezetimibe and simvastatin in pure powder, binary mixtures, and a combined dosage form by spectrophotometry, chemometry, and high-performance column liquid chromatography. Journal of AOAC International 20100101
Efficacy and safety of ezetimibe and low-dose simvastatin as primary treatment for dyslipidemia in peritoneal dialysis patients. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20100101
Primary prevention of CVD: treating dyslipidaemia. BMJ clinical evidence 20100101
Pleiotropic effects of rosuvastatin on microvascular function in type 2 diabetes. Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems. Cholesterol 20100101
Cardiovascular and smooth muscle pharmacology in the next decade. Frontiers in pharmacology 20100101
Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia. Drug, healthcare and patient safety 20100101
A patient's informative mistake: niacin is very effective in correcting dyslipidaemia. BMJ case reports 20100101
A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy. Clinical pharmacology : advances and applications 20100101
Pharmacological management of metabolic syndrome and its lipid complications. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
[Statin plus niacin or ezetimibe? What combination for which patients?]. MMW Fortschritte der Medizin 20091203
Ezetimibe decreases serum levels of asymmetric dimethylarginine (ADMA) and ameliorates renal injury in non-diabetic chronic kidney disease patients in a cholesterol-independent manner. Pharmacological research 20091201
High resolution magnetic resonance imaging in atherosclerotic mice treated with ezetimibe. The international journal of cardiovascular imaging 20091201
Statins, fibrates, nicotinic acid, cholesterol absorption inhibitors, anion-exchange resins, omega-3 fatty acids: which drugs for which patients? Fundamental & clinical pharmacology 20091201
Efficacy and safety of ezetimibe plus orlistat or rimonabant in statin-intolerant nondiabetic overweight/obese patients with dyslipidemia. Journal of cardiovascular pharmacology and therapeutics 20091201
The impact of ezetimibe on endothelial function and other markers of cardiovascular risk. The Annals of pharmacotherapy 20091201
Low-density lipoprotein cholesterol reduction and goal achievement with ezetimibe/simvastatin versus atorvastatin or rosuvastatin in patients with diabetes, metabolic syndrome, or neither disease, stratified by National Cholesterol Education Program risk category. Metabolic syndrome and related disorders 20091201
Policies to enhance the efficiency of prescribing in the Spanish Catalan region: impact and future direction. Expert review of pharmacoeconomics & outcomes research 20091201
Safety and efficacy of combined ezetimibe/simvastatin treatment and simvastatin monotherapy in patients with non-alcoholic fatty liver disease. Medical science monitor : international medical journal of experimental and clinical research 20091201
Xanthomas associated with homozygous familial hypercholesterolemia. Pharmacotherapy 20091201
Efficacy of combination drug pulse therapy in maintaining lipid levels in patients intolerant of daily statin use. Journal of clinical hypertension (Greenwich, Conn.) 20091201
[Ezetimibe (Ezetrol) in patients with diabetes]. Revue medicale de Liege 20091201
Potential of ezetimibe in memory deficits associated with dementia of Alzheimer's type in mice. Indian journal of pharmacology 20091201
The HALTS trial--halting atherosclerosis or halted too early? The New England journal of medicine 20091126
Extended-release niacin or ezetimibe and carotid intima-media thickness. The New England journal of medicine 20091126
Statin therapy with ezetimibe or niacin in high-risk patients. The New England journal of medicine 20091126
Systematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia. Annals of internal medicine 20091103
A novel cholesterol absorption inhibitor, ezetimibe, decreases adipose-derived and vascular PAI-1 expression in vivo. Thrombosis research 20091101
Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin. Experimental cell research 20091101
Lipid lowering versus pleiotropic effects of statins on skin microvascular function in patients with dysglycaemia and coronary artery disease. Journal of internal medicine 20091101
Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance. American journal of physiology. Endocrinology and metabolism 20091101
Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect. Arteriosclerosis, thrombosis, and vascular biology 20091101
Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate. Journal of industrial microbiology & biotechnology 20091101
A multi-center, open label, crossover designed prospective study evaluating the effects of lipid lowering treatment on steroid synthesis in patients with Type 2 diabetes (MODEST Study). Journal of endocrinological investigation 20091101
Hypertension and diabetes: should we treat early surrogates? What are the cons? Diabetes care 20091101
American Diabetes Association indications for statins in diabetes: is there evidence? Diabetes care 20091101
Ezetimibe/simvastatin. Expert opinion on drug safety 20091101
Lipid disorders. JAAPA : official journal of the American Academy of Physician Assistants 20091101
Short-term ezetimibe is well tolerated and effective in combination with statin therapy to treat elevated LDL cholesterol in HIV-infected patients. AIDS (London, England) 20091023
Rapid and sensitive simultaneous determination of ezetimibe and simvastatin from their combination drug products by monolithic silica high-performance liquid chromatographic column. Journal of pharmaceutical and biomedical analysis 20091015
Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men. Journal of lipid research 20091001
Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux. Journal of lipid research 20091001
At sea with SEAS: the first clinical endpoint trial for ezetimibe, treatment of patients with mild to moderate aortic stenosis, ends with mixed results and more controversy. Heart, lung & circulation 20091001
Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance. Diabetes 20091001
Low LDL cholesterol, albuminuria, and statins for the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry. Diabetes care 20091001
Clinical experience with ezetimibe/simvastatin in a Mediterranean population. Current medical research and opinion 20091001
Ezetimibe inhibits expression of acid sphingomyelinase in liver and intestine. Lipids 20091001
[LDL-cholesterol goals and changes in C reactive protein in high coronary risk patients]. Revista clinica espanola 20091001
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20091001
Usefulness of statin-ezetimibe combination to reduce the care gap in dyslipidemia management in patients with a high risk of atherosclerotic disease. The American journal of cardiology 20090915
Steatocholecystitis and fatty gallbladder disease. Digestive diseases and sciences 20090901
Effect of ezetimibe/simvastatin compared with atorvastatin on lipoprotein subclasses in patients with type 2 diabetes and hypercholesterolaemia. Diabetes, obesity & metabolism 20090901
The role of transporters in the pharmacokinetics of orally administered drugs. Pharmaceutical research 20090901
Long-term combination therapy of ezetimibe and acarbose for non-alcoholic fatty liver disease. Journal of hepatology 20090901
Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand. Bioorganic & medicinal chemistry letters 20090901
Lipid-lowering drugs and risk for cancer. Current atherosclerosis reports 20090901
Lipid lowering and aortic valve disease. Current atherosclerosis reports 20090901
Increased epistaxis with use of ezetimibe/simvastatin. The Annals of pharmacotherapy 20090901
The mechanism and mitigation of niacin-induced flushing. International journal of clinical practice 20090901
Letter by Westerink and Visseren regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'. Circulation 20090901
Letter by Tershakovec et al regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'. Circulation 20090901
Letter by Settergren et al regarding article, 'Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation'. Circulation 20090901
The efficacy and safety of ezetimibe and low-dose simvastatin as a primary treatment for dyslipidemia in renal transplant recipients. The Korean journal of internal medicine 20090901
The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study. Expert review of cardiovascular therapy 20090901
Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. PLoS medicine 20090901
Investigation of beta-carotene and lutein transport in Caco-2 cells: carotenoid-carotenoid interactions and transport inhibition by ezetimibe. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20090901
Premature release of data from clinical trials of ezetimibe. The New England journal of medicine 20090813
Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption. Journal of lipid research 20090801
Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2. Drug metabolism and disposition: the biological fate of chemicals 20090801
Ezetimibe improves postprandial hyperlipidaemia in patients with type IIb hyperlipidaemia. European journal of clinical investigation 20090801
Update on patented cholesterol absorption inhibitors. Expert opinion on therapeutic patents 20090801
Ezetimibe--an update. Drug and therapeutics bulletin 20090801
Familial hypercholesterolaemia: different perspectives. Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20090801
Effects of lifestyle counseling and combination lipid-modifying therapy on lipoprotein-associated phospholipase A2 mass concentration. Journal of clinical lipidology 20090801
Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds. Journal of pharmaceutical sciences 20090701
Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study. Atherosclerosis 20090701
Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter. Biochimica et biophysica acta 20090701
Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia. Journal of lipid research 20090701
Ezetimibe and atorvastatin both immunoregulate CD4+ T cells from cardiac transplant recipients invitro. Transplant immunology 20090701
The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study. Journal of clinical pharmacology 20090701
Narrative review: statin-related myopathy. Annals of internal medicine 20090616
Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study). The American journal of cardiology 20090615
The effects of ezetimibe on LDL-cholesterol: quantitative or qualitative changes? Atherosclerosis 20090601
Ezetimibe treatment of pediatric patients with hypercholesterolemia. The Journal of pediatrics 20090601
Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities. The Journal of pharmacology and experimental therapeutics 20090601
Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles. European journal of clinical investigation 20090601
Effect on serum lipid levels of switching dose of ezetimibe from 10 to 5 mg. The American journal of cardiology 20090601
Quantitative analysis of ezetimibe in human plasma by gas chromatography-mass spectrometry. Journal of separation science 20090601
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20090601
Efficacy and safety of ezetimibe/simvastatin association on non-diabetic and diabetic patients with polygenic hypercholesterolemia or combined hyperlipidemia and previously intolerant to standard statin treatment. Journal of clinical pharmacy and therapeutics 20090601
Drugs for children with hypercholesterolemia: be cautious. Journal of pediatric endocrinology & metabolism : JPEM 20090601
Ezetimibe as monotherapy in the treatment of hypercholesterolemia in children and adolescents. Journal of pediatric endocrinology & metabolism : JPEM 20090601
[Effectiveness of ezetimibe in improving lipid goal attainment in patients with coronary heart diseases treated with statin]. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20090601
[Efficacy and safety of ezetimibe/simvastatin combination therapy in patients with type 2 diabetes and nonalcoholic fatty liver disease]. Orvosi hetilap 20090524
The impact of ezetimibe and high-dose of statin treatment on LDL levels in patients with heterozygous familial hypercholesterolemia. International journal of cardiology 20090515
Ezetimibe monotherapy for cholesterol lowering in 2,722 people: systematic review and meta-analysis of randomized controlled trials. Journal of internal medicine 20090501
Fact or fiction: the need for independent pharmaceutical policy research. Journal of general internal medicine 20090501
Safety and effectiveness of ezetimibe in liver transplant recipients with hypercholesterolemia. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20090501
Utility of ezetimibe. The American journal of cardiology 20090501
What role for [black triangle down] colesevelam in cardiovascular prevention? Drug and therapeutics bulletin 20090501
[Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease]. Zhonghua xin xue guan bing za zhi 20090501
An assessment of the carcinogenic potential of ezetimibe using nonclinical data in a weight-of-evidence approach. Toxicology 20090428
Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish. Circulation research 20090424
2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors. European journal of medicinal chemistry 20090401
Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes 20090401
Increased persistency in medication use by U.S. Medicare beneficiaries with diabetes is associated with lower hospitalization rates and cost savings. Diabetes care 20090401
Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect. British journal of pharmacology 20090401
Lipid-altering efficacy of ezetimibe/simvastatin 10/20 mg compared with rosuvastatin 10 mg in high-risk hypercholesterolaemic patients inadequately controlled with prior statin monotherapy - The IN-CROSS study. International journal of clinical practice 20090401
Statin and ezetimibe combination therapy in cardiovascular disease. Current opinion in endocrinology, diabetes, and obesity 20090401
The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels. Journal of human genetics 20090401
Accelerated atherosclerosis in systemic lupus erythematosus: perspectives towards decreasing cardiovascular morbidity and mortality. Lupus 20090401
Low-density lipoprotein cholesterol reduction and prevention of cardiovascular disease. Mayo Clinic proceedings 20090401
Impact of ezetimibe on atherosclerosis: is the jury still out? Mayo Clinic proceedings 20090401
Preparation and physicochemical characterization of surfactant based solid dispersions of ezetimibe. Die Pharmazie 20090401
The Zetia challenge: an update. The Johns Hopkins medical letter health after 50 20090401
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20090401
Low-flow aortic stenosis in asymptomatic patients: valvular-arterial impedance and systolic function from the SEAS Substudy. JACC. Cardiovascular imaging 20090401
Aortic stenosis: look globally, think globally. JACC. Cardiovascular imaging 20090401
Ezetimibe - new anti-atherogenic properties? British journal of pharmacology 20090401
Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. Clinical and translational science 20090401
Add-on therapy for hypercholesterolemia: a pilot comparison of two gastrointestinally-acting agents in statin-treated patients. Journal of clinical lipidology 20090401
Ezetimibe, and the combination of ezetimibe/simvastatin, and risk of cancer: A post-marketing analysis. Journal of clinical lipidology 20090401
The efficacy and tolerability of ezetimibe in cardiac transplant recipients taking cyclosporin. Transplantation 20090315
Vascular protective effects of ezetimibe in ApoE-deficient mice. Atherosclerosis 20090301
Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes. Atherosclerosis 20090301
Role of ezetimibe in the management of patients with atherosclerosis. Coronary artery disease 20090301
Ezetimibe is an inhibitor of tumor angiogenesis. The American journal of pathology 20090301
Lowering low-density lipoprotein cholesterol: statins, ezetimibe, bile acid sequestrants, and combinations: comparative efficacy and safety. Endocrinology and metabolism clinics of North America 20090301
Statins reduce the neurofibrillary tangle burden in a mouse model of tauopathy. Journal of neuropathology and experimental neurology 20090301
Simvastatin with or without ezetimibe in familial hypercholesterolemia (the ENHANCE trial). Current atherosclerosis reports 20090301
Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis (the SEAS trial). Current atherosclerosis reports 20090301
[semFYC and ezetimib]. Atencion primaria 20090301
The use of lipid-lowering drug therapy in children and adolescents. Current opinion in investigational drugs (London, England : 2000) 20090301
['The lower LDL cholesterol levels, the better' still valid. Negative/neutral conclusions of three studies on statins do not change the clinical practice]. Lakartidningen 20090301
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20090301
Ezetimibe lowers cholesterol levels. Project Inform perspective 20090301
Amid lingering questions, FDA reprieves LDL cholesterol-lowering medication. JAMA 20090225
The effect of exogenous cholesterol and lipid-modulating agents on enterocytic amyloid-beta abundance. The British journal of nutrition 20090201
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. Journal of lipid research 20090201
On the road to better dyslipidemia outcomes. The Nurse practitioner 20090201
Controversial role of plant sterol esters in the management of hypercholesterolaemia. European heart journal 20090201
Pooled analyses of effects on C-reactive protein and low density lipoprotein cholesterol in placebo-controlled trials of ezetimibe monotherapy or ezetimibe added to baseline statin therapy. The American journal of cardiology 20090201
Perspectives on low-density lipoprotein cholesterol goal achievement. Current medical research and opinion 20090201
Colesevelam hydrochloride: usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20090201
Ask the doctor. Can muscle damage from a statin, or from strenuous exercise, elevate creatinine even after I stopped taking the statin and exercising but continue to take Zetia and Diovan HCT? Harvard heart letter : from Harvard Medical School 20090201
Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Circulation 20090106
Asymmetric dimethylarginine and the effect of folate substitution in children with familial hypercholesterolemia and diabetes mellitus type 1. Physiological research 20090101
Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS-deficient ApoE ko mice. Atherosclerosis 20090101
The effect of statin alone or in combination with ezetimibe on postprandial lipoprotein composition in obese metabolic syndrome patients. Atherosclerosis 20090101
Use of ezetimibe during HIV infection. The Journal of antimicrobial chemotherapy 20090101
Is there evidence-based hypolipidemic treatment with clinical benefit beyond statins? Angiology 20090101
After the failure of ENHANCEd cholesterol lowering in familial hypercholesterolemia, SEAS of problems with ezetimibe. Angiology 20090101
Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20090101
Lack of pharmacokinetic interaction of mipomersen sodium (ISIS 301012), a 2'-O-methoxyethyl modified antisense oligonucleotide targeting apolipoprotein B-100 messenger RNA, with simvastatin and ezetimibe. Clinical pharmacokinetics 20090101
Should we treat all primary prevention patients with statins? Current atherosclerosis reports 20090101
A review of trials evaluating nonstatin lipid-lowering therapies. Current atherosclerosis reports 20090101
Novel nonstatin strategies to lower low-density lipoprotein cholesterol. Current atherosclerosis reports 20090101
Simvastatin with or without ezetimibe in familial hypercholesterolemia. Current atherosclerosis reports 20090101
Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia. Journal of natural products 20090101
Standards of medical care in diabetes--2009. Diabetes care 20090101
Calcific aortic stenosis. The New England journal of medicine 20090101
Analyses of cancer data from three ezetimibe trials. The New England journal of medicine 20090101
No effect of lipid lowering on platelet activity in patients with coronary artery disease and type 2 diabetes or impaired glucose tolerance. Thrombosis and haemostasis 20090101
[Orange skin and xanthomas associated with lycopenaemia in a setting of type III dyslipoproteinemia]. Annales de dermatologie et de venereologie 20090101
Lipid-lowering drugs acting at the level of the gastrointestinal tract. Current pharmaceutical design 20090101
ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model. BMC cardiovascular disorders 20090101
Efficacy and safety of coadministration of fenofibrate and ezetimibe compared with each as monotherapy in patients with type IIb dyslipidemia and features of the metabolic syndrome: a prospective, randomized, double-blind, three-parallel arm, multicenter, comparative study. American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101
Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship. PloS one 20090101
Medicinal treatments of cholesterol gallstones: old, current and new perspectives. Current medicinal chemistry 20090101
Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101
Impact of ezetimibe on cholesterol subfractions in dyslipidemic cardiac transplant recipients receiving statin therapy. Clinical transplantation 20090101
Efficacy and safety of rosuvastatin in the management of dyslipidemia. Vascular health and risk management 20090101
Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin. Vascular health and risk management 20090101
The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man. Vascular health and risk management 20090101
Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people. BMC clinical pharmacology 20090101
The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe. Molecular pharmaceutics 20090101
Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis. Cardiovascular diabetology 20090101
Mechanism of inhibitory effect of atorvastatin on resistin expression induced by tumor necrosis factor-alpha in macrophages. Journal of biomedical science 20090101
Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk. Vascular health and risk management 20090101
Coronary heart disease and dyslipidemia: a cross-sectional evaluation of prevalence, current treatment, and clinical control in a large cohort of Spanish high-risk patients: the PRINCEPS study. Preventive cardiology 20090101
LDL-Cholesterol is the King. Angiology 20090101
Kidney function and estimated vascular risk in patients with primary dyslipidemia. The open cardiovascular medicine journal 20090101
Lipoproteins, cholesterol homeostasis and cardiac health. International journal of biological sciences 20090101
Regulation of bile acid and cholesterol metabolism by PPARs. PPAR research 20090101
Translocation of bacterial NOD2 agonist and its link with inflammation. Critical care (London, England) 20090101
Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet. Lipids in health and disease 20090101
New options in the treatment of lipid disorders in HIV-infected patients. The open AIDS journal 20090101
Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry. BMC public health 20090101
Safety of the combination of intensive cholesterol-lowering therapy with oral anticoagulation medication in elderly patients with atrial fibrillation: a randomized, double-blind, placebo-controlled study. Drugs & aging 20090101
Disappointing recent cholesterol-lowering drug trials: is it not time for a full reappraisal of the cholesterol theory? World review of nutrition and dietetics 20090101
Low and high density lipoprotein--cholesterol and coronary atherothrombosis. Medicinski pregled 20090101
Cardiovascular disease in patients with chronic kidney disease. Vascular health and risk management 20090101
Statins and ezetimibe modulate plasma proprotein convertase subtilisin kexin-9 (PCSK9) levels. Transactions of the American Clinical and Climatological Association 20090101
Drugs associated with more suicidal ideations are also associated with more suicide attempts. PloS one 20090101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20090101
Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia. Lipids in health and disease 20090101
Vancomycin-induced thrombocytopenia in a 60-year-old man: a case report. Journal of medical case reports 20090101
Triple X syndrome in a patient with partial lipodystrophy discovered using a high-density oligonucleotide microarray: a case report. Journal of medical case reports 20090101
Rosuvastatin increased serum osteocalcin levels independent of its serum cholesterol-lowering effect in patients with type 2 diabetes and hypercholesterolemia. Internal medicine (Tokyo, Japan) 20090101
Pleiotropic vasoprotective effects of statins: the chicken or the egg? Drug design, development and therapy 20090101
Hypercholesterolemia and myocardial function evaluated via tissue doppler imaging. Cardiovascular ultrasound 20090101
Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice. PloS one 20090101
Management of dyslipidemia in children. Diabetology & metabolic syndrome 20090101
Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients. Lipids in health and disease 20090101
Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals. Vascular health and risk management 20090101
Vascular health in children and adolescents: effects of obesity and diabetes. Vascular health and risk management 20090101
[Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study]. Wiener medizinische Wochenschrift (1946) 20090101
Review of extended-release niacin/laropiprant fixed combination in the treatment of mixed dyslipidemia and primary hypercholesterolemia. Vascular health and risk management 20090101
Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia. Lipids in health and disease 20090101
Model system for the analysis of cell surface expression of human ABCA1. BMC cell biology 20090101
The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences. Vascular health and risk management 20090101
Management of asymptomatic severe aortic stenosis. Current cardiology reviews 20090101
A comparative evaluation of safety and efficacy of rosuvastatin, simvastatin, and atorvastatin in patients of type 2 diabetes mellitus with dyslipidemia. International journal of diabetes in developing countries 20090101
Recent advances in medical treatment and percutaneous, transapical and surgical interventions in aortic-valve stenosis. F1000 medicine reports 20090101
Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective. Diabetes, metabolic syndrome and obesity : targets and therapy 20090101
A review of the current status of the management of mixed dyslipidemia associated with diabetes mellitus and metabolic syndrome. The American journal of cardiology 20081222
Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial. Journal of the American College of Cardiology 20081216
Additional lipid lowering trials using surrogate measurements of atherosclerosis by carotid intima-media thickness: more clarity or confusion? Journal of the American College of Cardiology 20081216
Lipid-lowering therapy does not affect the postprandial drop in high density lipoprotein-cholesterol (HDL-c) plasma levels in obese men with metabolic syndrome: a randomized double blind crossover trial. Clinical endocrinology 20081201
VAP II analysis of lipoprotein subclasses in mixed hyperlipidemic patients on treatment with ezetimibe/simvastatin and fenofibrate. Journal of lipid research 20081201
Origins of intestinal ABCA1-mediated HDL-cholesterol. Journal of lipid research 20081201
Formulation and in vivo evaluation of self-nanoemulsifying granules for oral delivery of a combination of ezetimibe and simvastatin. Drug development and industrial pharmacy 20081201
Is there a problem with ezetimibe or just ENHANCEd hype? Angiology 20081201
Effect of ezetimibe on plasma cholesterol levels, cholesterol absorption, and secretion of biliary cholesterol in laboratory opossums with high and low responses to dietary cholesterol. Metabolism: clinical and experimental 20081201
Efficacy and safety of ezetimibe added on to atorvastatin (20 mg) versus uptitration of atorvastatin (to 40 mg) in hypercholesterolemic patients at moderately high risk for coronary heart disease. The American journal of cardiology 20081201
Efficacy and safety of ezetimibe added on to atorvastatin (40 mg) compared with uptitration of atorvastatin (to 80 mg) in hypercholesterolemic patients at high risk of coronary heart disease. The American journal of cardiology 20081201
Intensive lipid-lowering therapy for patients with aortic stenosis. The American journal of cardiology 20081201
The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia. Expert opinion on pharmacotherapy 20081201
Ezetimibe in the treatment of uncontrolled hyperlipidemia in kidney transplant patients. Transplantation proceedings 20081201
The top 10 health stories of 2008. Harvard health letter 20081201
Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients. Clinical therapeutics 20081201
SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. The Journal of clinical investigation 20081103
Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy. European heart journal 20081101
Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study. European heart journal 20081101
Long-term safety and tolerability of ezetimibe coadministered with simvastatin in hypercholesterolemic patients: a randomized, 12-month double-blind extension study. Current medical research and opinion 20081101
Effectiveness of thrice weekly ezetimibe. The American journal of cardiology 20081101
LDL reduction: how low should we go and is it safe? Current cardiology reports 20081101
American College of Endocrinology Pre-Diabetes Consensus Conference: part two. Diabetes care 20081101
Is carotid intima-media thickness a reliable clinical predictor? Mayo Clinic proceedings 20081101
Informed consent and shared decision-making: a requirement to disclose to patients off-label prescriptions. PLoS medicine 20081101
Treatment with ezetimibe in kidney transplant recipients with uncontrolled dyslipidemia. Transplantation proceedings 20081101
Safety and efficacy of ezetimibe in a sample of cardiac transplant patients. Transplantation proceedings 20081101
The efficacy and safety of ezetimibe for treatment of dyslipidemia after heart transplantation. Transplantation proceedings 20081101
Uncertainty dogs Zetia and Vytorin. Harvard heart letter : from Harvard Medical School 20081101
Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. American heart journal 20081101
The ENHANCE trial. Cleveland Clinic journal of medicine 20081101
The ENHANCE trial. Cleveland Clinic journal of medicine 20081101
Efficacy and safety of coadministration of ezetimibe and simvastatin in adolescents with heterozygous familial hypercholesterolemia. Journal of the American College of Cardiology 20081021
Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015
Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081002
Quantitative 3T MR imaging of the descending thoracic aorta: patients with familial hypercholesterolemia have an increased aortic plaque burden despite long-term lipid-lowering therapy. Journal of vascular and interventional radiology : JVIR 20081001
Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters. American journal of physiology. Gastrointestinal and liver physiology 20081001
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. American journal of physiology. Gastrointestinal and liver physiology 20081001
Sustained effects in hypercholesterolaemic patients on combined simvastatin/ezetimibe treatment: observational cohort study in clinical practice. Current medical research and opinion 20081001
Ptosis, diplopia and statins: an association? European journal of neurology 20081001
[Therapy of familial hypercholesterolemia with or without ezetimibe]. Der Internist 20081001
Therapy and clinical trials. Current opinion in lipidology 20081001
Long-term (48-week) safety of ezetimibe 10 mg/day coadministered with simvastatin compared to simvastatin alone in patients with primary hypercholesterolemia. Current medical research and opinion 20081001
Left ventricular systolic and diastolic function in asymptomatic patients with moderate aortic stenosis. The American journal of cardiology 20081001
American College Of Endocrinology Pre-Diabetes Consensus Conference: part one. Diabetes care 20081001
Muddy waters: more stormy SEAS for ezetimibe. International journal of clinical practice 20081001
Long-term efficacy and safety of ezetimibe 10 mg in patients with homozygous sitosterolemia: a 2-year, open-label extension study. International journal of clinical practice 20081001
Ezetimibe 5 and 10 mg for lowering LDL-C: potential billion-dollar savings with improved tolerability. The American journal of managed care 20081001
On call. I don't understand the problem with Vytorin. The two components when used separately work fine, but when mixed together things change. Why? Harvard men's health watch 20081001
Renal failure and rhabdomyolysis associated with sitagliptin and simvastatin use. Diabetic medicine : a journal of the British Diabetic Association 20081001
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20081001
Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing. Vascular health and risk management 20081001
A Commentary on the implications of the ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression) Trial: Should ezetimibe move to the 'Back of the Line' as a therapy for dyslipidemia? Journal of clinical lipidology 20081001
Ezetimibe-related myopathy: A systematic review. Journal of clinical lipidology 20081001
Optimal management of lipids in diabetes and metabolic syndrome. Journal of clinical lipidology 20081001
Neuropharmacology. Indian journal of pharmacology 20081001
Analyses of cancer data from three ezetimibe trials. The New England journal of medicine 20080925
Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. The New England journal of medicine 20080925
Ezetimibe and cancer--an uncertain association. The New England journal of medicine 20080925
Identifying and addressing safety signals in clinical trials. The New England journal of medicine 20080925
Hypercholesterolaemia: Clarifications from adverse drug reactions agency. BMJ (Clinical research ed.) 20080916
After ENHANCE: the cholesterol hypothesis is alive and well. The Medical journal of Australia 20080915
[Ezetimibe=cost effectiveness. Science or a debate contribution from MSD?]. Ugeskrift for laeger 20080915
[The evidence of clinical effects of ezetimibe is not sufficient]. Ugeskrift for laeger 20080915
Reasons to be cautious about cholesterol lowering drugs. BMJ (Clinical research ed.) 20080903
Safety and efficacy of ezetimibe monotherapy in 1624 primary hypercholesterolaemic patients for up to 2 years. International journal of clinical practice 20080901
Cholesterol homeostasis by the intestine: lessons from Niemann-Pick C1 Like 1 [NPC1L1). Atherosclerosis. Supplements 20080901
CD8+ cutaneous T-cell lymphoma successfully treated with bexarotene: a case report and review of the literature. American journal of hematology 20080901
Statin plus ezetimibe treatment in clinical practice: the SI-SPECT (Slovenia (SI) Statin Plus Ezetimibe in Cholesterol Treatment) monitoring of clinical practice study. Current medical research and opinion 20080901
The development of novel anti-hyperlipidemic drugs: a tough business gets tougher. Current opinion in investigational drugs (London, England : 2000) 20080901
Simvastatin-ezetimibe-induced hepatic failure necessitating liver transplantation. Pharmacotherapy 20080901
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Does 'ENHANCE' diminish confidence in ezetimibe? The Journal of the Association of Physicians of India 20080901
Preliminary observations from preliminary trial results: have we finally had enough? Circulation. Cardiovascular quality and outcomes 20080901
Serious drug-induced liver disease secondary to ezetimibe. World journal of gastroenterology 20080828
Ezetimibe revisited. The Medical letter on drugs and therapeutics 20080825
Stages of motor output reorganization after hemispheric stroke suggested by longitudinal studies of cortical physiology. Cerebral cortex (New York, N.Y. : 1991) 20080801
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nature clinical practice. Cardiovascular medicine 20080801
Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit. Cardiovascular drugs and therapy 20080801
Subclinical atherosclerosis: what it is, what it means and what we can do about it. International journal of clinical practice 20080801
Effects of ezetimibe, either alone or in combination with atorvastatin, on serum visfatin levels: a pilot study. Expert opinion on pharmacotherapy 20080801
Enhanced hype. The American journal of cardiology 20080801
Beneficial effects of ezetimibe-based therapy in patients with dyslipidemia. Journal of cardiology 20080801
The effects of low-dose simvastatin and ezetimibe compared to high-dose simvastatin alone on post-fat load endothelial function in patients with metabolic syndrome: a randomized double-blind crossover trial. Journal of cardiovascular pharmacology 20080801
Intensive lipid intervention in the post-ENHANCE era. Mayo Clinic proceedings 20080801
Cardiovascular prevention (VI). Use of drugs in the primary prevention of arterial hypertension and dyslipidemia. Revista espanola de cardiologia 20080801
A novel approach for prevention and dissolution of cholesterol gallstones. Liver international : official journal of the International Association for the Study of the Liver 20080801
Ezetimibe prevents cholesterol gallstone formation in mice. Liver international : official journal of the International Association for the Study of the Liver 20080801
Estimating the health benefits and costs associated with ezetimibe coadministered with statin therapy compared with higher dose statin monotherapy in patients with established cardiovascular disease: results of a Markov model for UK costs using data registries. Clinical therapeutics 20080801
The Relationship Between HIV Infection and Cardiovascular Disease. Current cardiology reviews 20080801
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080731
Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Human molecular genetics 20080715
[Effectiveness of cardiometabolic risk reduction in patients with type 1 diabetes mellitus]. Orvosi hetilap 20080706
[Crosstalk between cholesterol homeostasis and drug metabolism]. Orvosi hetilap 20080706
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Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages. Arteriosclerosis, thrombosis, and vascular biology 20080701
Cholesterol lowering is more important than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease. European heart journal 20080701
Efficacy and safety of ezetimibe 40 mg vs. ezetimibe 10 mg in the treatment of patients with homozygous sitosterolaemia. International journal of clinical practice 20080701
The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia. Current medical research and opinion 20080701
Effect of ezetimibe coadministration with simvastatin in a Middle Eastern population: a prospective, multicentre, randomized, double-blind, placebo-controlled trial. Journal of cardiovascular medicine (Hagerstown, Md.) 20080701
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1. Pharmacogenetics and genomics 20080701
Is it over for ezetimibe? Expert review of cardiovascular therapy 20080701
Highlights from the 57th annual scientific session of the American College of Cardiology. The Journal of thoracic and cardiovascular surgery 20080701
A drug, a concept, and a clinical trial on trial. Cleveland Clinic journal of medicine 20080701
Is ezetimibe/simvastatin no better than simvastatin alone? Lessons learned and clinical implications. Cleveland Clinic journal of medicine 20080701
Given the ENHANCE trial results, ezetimibe is still unproven. Cleveland Clinic journal of medicine 20080701
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin. Clinical lung cancer 20080701
Rhabdomyolysis and pancreatitis associated with coadministration of danazol 600 mg/d and lovastatin 40 mg/d. Clinical therapeutics 20080701
Simvastatin and ezetimibe in addition to nonpharmacological risk factor modification for achieving new low-density lipoprotein cholesterol targets. Herz 20080701
[Cost effectiveness in the Danish health care of ezetemibe co-administration compared to simvastatin]. Ugeskrift for laeger 20080623
The ENHANCE study and marketing ezetimibe. JAMA 20080618
Efficacy of rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins. The American journal of cardiology 20080615
Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. The Journal of biological chemistry 20080606
[Stable coronary heart disease--lessons from the COURAGE Study. With intensive drug therapy on the success track]. MMW Fortschritte der Medizin 20080605
[Dual cholesterol inhibition. More high risk patients achieve LDL cholesterol values below 100 mg/dl]. MMW Fortschritte der Medizin 20080605
After ENHANCE: is more LDL cholesterol lowering even better? Clinical chemistry 20080601
Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones. Gastroenterology 20080601
Predictors of uncontrolled hyperlipidaemia in high-risk ambulatory patients in primary care. Current medical research and opinion 20080601
The structure and function of Niemann-Pick C1-like 1 protein. Current opinion in lipidology 20080601
Severe jaundice following treatment with ezetimibe. European journal of gastroenterology & hepatology 20080601
Review of side-effect profile of combination ezetimibe and statin therapy in randomized clinical trials. The American journal of cardiology 20080601
Effects of fenofibrate and ezetimibe, both as monotherapy and in coadministration, on cholesterol mass within lipoprotein subfractions and low-density lipoprotein peak particle size in patients with mixed hyperlipidemia. Metabolism: clinical and experimental 20080601
Safety and efficacy of ezetimibe with low doses of simvastatin in heart transplant recipients. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080601
Ezetimibe blocks internalization of the NPC1L1/cholesterol complex. Cell metabolism 20080601
The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. Cell metabolism 20080601
Toward 'pain-free' statin prescribing: clinical algorithm for diagnosis and management of myalgia. Mayo Clinic proceedings 20080601
Emerging antidyslipidemic drugs. Expert opinion on emerging drugs 20080601
The implications of the ezetimibe and simvastatin in hypercholesterolemia enhances atherosclerosis regression trial: a return to first principles. Clinical cardiology 20080601
[Lower is better: ENHANCE affair]. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20080601
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20080601
Elevated atherogenic lipoproteins in childhood: Risk, prevention, and treatment. Journal of clinical lipidology 20080601
Pediatric dyslipidemias: Prescription medication efficacy and safety. Journal of clinical lipidology 20080601
Cholesterol drug controversy continues. JAMA 20080521
Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men. Atherosclerosis 20080501
Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice. Atherosclerosis 20080501
SREBP-1c gene polymorphism is associated with increased inhibition of cholesterol-absorption in response to ezetimibe treatment. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20080501
HNF4alpha is a crucial modulator of the cholesterol-dependent regulation of NPC1L1. Pharmaceutical research 20080501
Ezetimibe's effect on platelet aggregation and LDL tendency to peroxidation in hypercholesterolaemia as monotherapy or in addition to simvastatin. British journal of clinical pharmacology 20080501
Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia: NICE technology appraisal guidance. Heart (British Cardiac Society) 20080501
Commentary on NICE technology appraisal guidance on ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia. Heart (British Cardiac Society) 20080501
ENHANCE: food for the ostriches. International journal of clinical practice 20080501
The ENHANCE Study: an unusual publication of trial data raises questions beyond ezetimibe. Expert opinion on pharmacotherapy 20080501
Switching statin therapy using a pharmacist-managed therapeutic conversion program versus usual care conversion among indigent patients. Pharmacotherapy 20080501
The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption. Thyroid : official journal of the American Thyroid Association 20080501
Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation. Health technology assessment (Winchester, England) 20080501
ENHANCE and ACCORD: controversy over surrogate end points. Current cardiology reports 20080501
Achieving target cholesterol levels in diabetic patients: potency of the statin or potency of the physician? The Israel Medical Association journal : IMAJ 20080501
[Commentary to the article: Kastelein JJ, Akdim F, Stroes ES, et al.; ENHANCE Investigators. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med 2008; 358: 1431-43 ]. Kardiologia polska 20080501
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20080501
Effectiveness of lipid-lowering therapy in HIV patients. Current opinion in HIV and AIDS 20080501
American college of cardiology 57th scientific sessions, 2008. P & T : a peer-reviewed journal for formulary management 20080501
Use of ezetimibe in the United States and Canada. The New England journal of medicine 20080424
Vascular effects of diet supplementation with plant sterols. Journal of the American College of Cardiology 20080422
Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia. Journal of the American College of Cardiology 20080422
[Dual lipid control without anti-atherosclerosis effect]. MMW Fortschritte der Medizin 20080417
Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice. European journal of pharmacology 20080414
Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England journal of medicine 20080403
Cholesterol lowering and ezetimibe. The New England journal of medicine 20080403
Does ENHANCE diminish confidence in lowering LDL or in ezetimibe? The New England journal of medicine 20080403
Mismanaged measures. Nature 20080403
Short-term treatment with ezetimibe, simvastatin or their combination does not alter circulating adiponectin, resistin or leptin levels in healthy men. Clinical endocrinology 20080401
Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake. Molecular pharmacology 20080401
Lipid-altering efficacy of ezetimibe/simvastatin 10/40 mg compared with doubling the statin dose in patients admitted to the hospital for a recent coronary event: the INFORCE study. International journal of clinical practice 20080401
Development and physiological regulation of intestinal lipid absorption. III. Intestinal transporters and cholesterol absorption. American journal of physiology. Gastrointestinal and liver physiology 20080401
Colesevelam hydrochloride in clinical practice: a new approach in the treatment of hypercholesterolaemia. Current medical research and opinion 20080401
Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization. Hepatology (Baltimore, Md.) 20080401
Enhanced LDL-C reduction: lower is better. Does it matter how? International journal of clinical practice 20080401
Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease. The American journal of cardiology 20080401
Left atrial volume in patients with asymptomatic aortic valve stenosis (the Simvastatin and Ezetimibe in Aortic Stenosis study). The American journal of cardiology 20080401
Lipid-lowering study raises issues of therapy's value. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080401
Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone. Gastroenterology 20080401
Ezetimibe: cholesterol lowering and beyond. Expert review of cardiovascular therapy 20080401
Development and validation of a stability-indicating micellar electrokinetic chromatography method for the determination of ezetimibe in pharmaceutical formulations. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080401
[Cost-effectiveness of managing familial hypercholesterolemia using atorvastatin-based preventive therapy]. Revista espanola de cardiologia 20080401
Combination therapy in cholesterol reduction: focus on ezetimibe and statins. Vascular health and risk management 20080401
Clinical efficacy and safety of statins in managing cardiovascular risk. Vascular health and risk management 20080401
Recent news reports suggest that the cholesterol medicine Zetia doesn't work. Should I stop taking my prescription? The Johns Hopkins medical letter health after 50 20080401
Surrogate end points and FDA approval: a tale of 2 lipid-altering drugs. JAMA 20080326
Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia. The Journal of biological chemistry 20080307
The efficacy of statin monotherapy uptitration versus switching to ezetimibe/simvastatin: results of the EASEGO study. Current medical research and opinion 20080301
Ezetimibe-associated immune thrombocytopenia. The Annals of pharmacotherapy 20080301
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat. Journal of cardiovascular pharmacology and therapeutics 20080301
An evaluation of rosuvastatin: pharmacokinetics, clinical efficacy and tolerability. Expert opinion on drug metabolism & toxicology 20080301
Rx for uncertainty. Does a popular cholesterol-lowering drug do what it's supposed to do? Diabetes forecast 20080301
Controversies surround heart drug study: questions about Vytorin and trial sponsors' conduct. JAMA 20080227
Critical lessons from the ENHANCE trial. JAMA 20080227
Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients. The American journal of cardiology 20080215
Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of muscle-related side effects with other statins. The American journal of cardiology 20080215
Factors influencing left ventricular structure and stress-corrected systolic function in men and women with asymptomatic aortic valve stenosis (a SEAS Substudy). The American journal of cardiology 20080215
Targets for intervention in dyslipidemia in diabetes. Diabetes care 20080201
Update on the use of fibrates: focus on bezafibrate. Vascular health and risk management 20080201
High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease. Vascular health and risk management 20080201
In brief: Zetia and Vytorin: the ENHANCE study. The Medical letter on drugs and therapeutics 20080128
Unreported cholesterol drug data released by company. BMJ (Clinical research ed.) 20080126
Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption. Bioorganic & medicinal chemistry letters 20080115
Ezetimibe treatment in hypercholesterolemic kidney transplant patients is safe and effective and reduces the decline of renal allograft function: a pilot study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080101
Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia. Current medical research and opinion 20080101
Ezetimibe plus simvastatin cardiovascular outcomes study program. Expert review of cardiovascular therapy 20080101
Human cholesterol metabolism and therapeutic molecules. Experimental physiology 20080101
Ezetimibe-associated adverse effects: what the clinician needs to know. International journal of clinical practice 20080101
Optimal management of combined dyslipidemia: what have we behind statins monotherapy? Advances in cardiology 20080101
Lipid profiles of patients with a transplanted heart before and after the operation. Transplantation proceedings 20080101
Lipid-lowering therapy in patients with type 2 diabetes: the case for early intervention. Diabetes/metabolism research and reviews 20080101
Should We Use PPAR Agonists to Reduce Cardiovascular Risk? PPAR research 20080101
Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study. Clinical therapeutics 20080101
The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease. BMC nephrology 20080101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20080101
Is Zetia a 'do nothing' drug? Current topics in medicinal chemistry 20080101
Fibrate therapy: an update. Cardiology in review 20080101
Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy. Clinical transplantation 20080101
The cholesterol hypothesis: questioned? American journal of therapeutics 20080101
Making sense of ENHANCE: ezetimibe (Zetia) lowers LDL cholesterol but doesn't decrease carotid intima-media thickness. The Mount Sinai journal of medicine, New York 20080101
[A new approach to the treatment of dyslipidemia]. Medicina (Kaunas, Lithuania) 20080101
Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism. Lipids in health and disease 20080101
ENHANCE results: a surrogate trial that impacts beyond size and scope. Cardiovascular journal of Africa 20080101
Ezetimibe, a selective inhibitor of the transport of cholesterol. Internal medicine (Tokyo, Japan) 20080101
Carotid intima-media thickness (cIMT): a useful clinic tool or research luxury? Another view of the ENHANCE trial. Angiology 20080101
Combination drug products: an indication for medication reconciliation and pharmacist counseling. Journal of the American Pharmacists Association : JAPhA 20080101
Acute myocardial infarction in an 18 year old South Indian girl with familial hypercholesterolemia: a case report. Cases journal 20080101
Current and future pharmacologic options for the management of patients unable to achieve low-density lipoprotein-cholesterol goals with statins. American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101
Monitoring therapeutical intervention with ezetimibe using targeted near-infrared fluorescence imaging in experimental atherosclerosis. Molecular imaging 20080101
[Cardiovascular mortality in kidney transplatation]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101
Gateways to clinical trials. July-August 2008. Methods and findings in experimental and clinical pharmacology 20080101
Dyslipidemia in primary care--prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS). Cardiovascular diabetology 20080101
Determination of nebivolol hydrochloride and hydrochlorothiazide in tablets by first-order derivative spectrophotometry and liquid chromatography. Journal of AOAC International 20080101
Mild-to-moderate aortic stenosis not improved by lipid-lowering therapy: SEAS study. Cardiovascular journal of Africa 20080101
Efficacy of statins in familial hypercholesterolaemia: a long term cohort study. BMJ (Clinical research ed.) 20080101
Practical management of dyslipidemia with elevated lipoprotein(a). Journal of the American Pharmacists Association : JAPhA 20080101
A randomised trial of three counselling strategies for lifestyle changes in patients with hypercholesterolemia treated with ezetimibe on top of statin therapy (TWICE). Archives of cardiovascular diseases 20080101
Plant sterols/stanols as cholesterol lowering agents: A meta-analysis of randomized controlled trials. Food & nutrition research 20080101
Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: a Markov model. American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101
Diabetes: managing dyslipidaemia. BMJ clinical evidence 20080101
UV and Three Derivative Spectrophotometric Methods for Determination of Ezetimibe in Tablet Formulation. Indian journal of pharmaceutical sciences 20080101
Standardization of PCR-RFLP analysis of nsSNP rs1468384 of NPC1L1 gene. Indian journal of human genetics 20080101
Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS letters 20071211
The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation. Inflammation 20071201
Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (-/-) mice. Journal of pharmaceutical sciences 20071201
Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting. The American journal of managed care 20071201
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20071201
Practical guidelines for familial combined hyperlipidemia diagnosis: an up-date. Vascular health and risk management 20071201
A retrospective study of the lipid-lowering efficacy and safety of ezetimibe added to hydroxy methylglutaryl coenzyme A reductase therapy in HIV-infected patients with hyperlipidemia. Journal of clinical lipidology 20071201
Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption? The Biochemical journal 20071115
Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex. Traffic (Copenhagen, Denmark) 20071101
Who needs to care about small, dense low-density lipoproteins? International journal of clinical practice 20071101
[Type 1 diabetes: what are the alternatives for lowering cholesterol levels with statins?]. Deutsche medizinische Wochenschrift (1946) 20071101
Prevalence of adequate and of optimal control of serum low-density lipoprotein cholesterol in an academic nursing home. Journal of the American Medical Directors Association 20071101
The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance. Fundamental & clinical pharmacology 20071101
Setting a new standard in achieving superior efficacy: ezetimibe + simvastatin. Fundamental & clinical pharmacology 20071101
Cholesterol absorption inhibitors in the treatment of hyperlipidemia: clinical outcomes in large clinical trials. Fundamental & clinical pharmacology 20071101
Lessons from 'lower' organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. PLoS genetics 20071101
Effects of ezetimibe/simvastatin on lipoprotein subfractions in patients with primary hypercholesterolemia: an exploratory analysis of archived samples using two commercially available techniques. Clinical therapeutics 20071101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20071101
[LDL cholesterol in cardiovascular risk patients should be as low as possible]. MMW Fortschritte der Medizin 20071011
Effect of ezetimibe coadministered with statins in genotype-confirmed heterozygous FH patients. Atherosclerosis 20071001
Differential effect of hypolipidemic drugs on lipoprotein-associated phospholipase A2. Arteriosclerosis, thrombosis, and vascular biology 20071001
ISIS 301012 gene therapy for hypercholesterolemia: sense, antisense, or nonsense? The Annals of pharmacotherapy 20071001
Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data. International journal of clinical practice 20071001
FPIN's clinical inquiries. Best alternatives to statins for treating hyperlipidemia. American family physician 20071001
[Severe progression of coronary heart disease in a patient with elevated lipoprotein (a) level in spite of optimal LDL-C decrease]. Herz 20071001
The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation. Vascular health and risk management 20071001
Cholesterol lowering for secondary prevention: what statin dose should we use? Vascular health and risk management 20071001
Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors. Vascular health and risk management 20071001
Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles. Biochimica et biophysica acta 20070901
Cholesterol-lowering effect of ezetimibe in uridine diphosphate glucuronosyltransferase 1A-deficient (Gunn) rats. Drug metabolism and disposition: the biological fate of chemicals 20070901
Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol. American journal of physiology. Endocrinology and metabolism 20070901
A multi-centre, randomised, double-blind 14-week extension study examining the long-term safety and efficacy profile of the ezetimibe/simvastatin combination tablet. International journal of clinical practice 20070901
Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans. Biochimica et biophysica acta 20070901
Reduction in estimated risk for coronary artery disease after use of ezetimibe with a statin. The Annals of pharmacotherapy 20070901
[Rhabdomyolysis associated to combined ezetimibe-statin treatment]. Revista clinica espanola 20070901
Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane. Biochimica et biophysica acta 20070901
Effect of ezetimibe in patients who cannot tolerate statins or cannot get to the low density lipoprotein cholesterol target despite taking a statin. Current medical research and opinion 20070901
Simvastatin: present and future perspectives. Expert opinion on pharmacotherapy 20070901
The clinical relevance of LDL size and subclasses modulation in patients with type-2 diabetes. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070901
Ezetimibe in search of receptor(s)--still a never-ending challenge in cholesterol absorption and transport. Biochimica et biophysica acta 20070901
Ezetimibe in heart transplantation: initial experience. Transplantation proceedings 20070901
Rational approach to the treatment for heterozygous familial hypercholesterolemia in childhood and adolescence: a review. Journal of endocrinological investigation 20070901
Case reports: alopecia universalis: hair growth following initiation of simvastatin and ezetimibe therapy. Journal of drugs in dermatology : JDD 20070901
[Drug of the month. Ezetimibe/simvastatin tablet (Inegy)]. Revue medicale de Liege 20070901
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20070901
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[New insights and perspectives in the management of dyslipidemia]. La Revue de medecine interne 20070801
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Design and rationale of the ARBITER 6 trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol)-6-HDL and LDL Treatment Strategies in Atherosclerosis (HALTS). Cardiovascular drugs and therapy 20070601
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The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin. Journal of lipid research 20070301
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Discontinuation of lipid modifying drugs among commercially insured United States patients in recent clinical practice. The American journal of cardiology 20070215
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The effect of simvastatin, ezetimibe and their combination on the lipid profile, arterial stiffness and inflammatory markers. European journal of clinical pharmacology 20070201
Drug-induced liver injury associated with ezetimibe therapy. Digestive diseases and sciences 20070201
Efficacy and safety of the coadministration of ezetimibe/simvastatin with fenofibrate in patients with mixed hyperlipidemia. American heart journal 20070201
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Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions. Bioorganic & medicinal chemistry letters 20070101
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Ezetimibe is effective when added to maximally tolerated lipid lowering therapy in patients with HIV. Lipids in health and disease 20070101
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Aspirin and Simvastatin Combination for Cardiovascular Events Prevention Trial in Diabetes (ACCEPT-D): design of a randomized study of the efficacy of low-dose aspirin in the prevention of cardiovascular events in subjects with diabetes mellitus treated with statins. Trials 20070101
An unusual exacerbation of chronic obstructive pulmonary disease (COPD) with herpes simplex tracheitis: case report. Journal of medical case reports 20070101
Ezetimibe reduces low-density lipoprotein cholesterol (LDL-C) in renal transplant patients resistant to HMG-CoA reductase inhibitors. American journal of therapeutics 20070101
[When should an association of lipid-lowering drugs be proposed in a patient failing to reach therapeutic targets under monotherapy? Guidelines of the New French Society of Atherosclerosis]. Archives des maladies du coeur et des vaisseaux 20070101
Stability-indicating reversed-phase liquid chromatographic method for simultaneous determination of simvastatin and ezetimibe from their combination drug products. Journal of AOAC International 20070101
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Stability-indicating reversed-phase liquid chromatographic method for simultaneous determination of atorvastatin and ezetimibe from their combination drug products. Journal of AOAC International 20070101
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Ezetimibe: New perspectives in lipid lowering treatment. Cardiology journal 20070101
Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats. Nutrition research and practice 20070101
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Low-density lipoprotein apheresis: an evidence-based analysis. Ontario health technology assessment series 20070101
The lipid-lowering effect of ezetimibe in pure vegetarians. Journal of lipid research 20061201
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NPC1L1: evolution from pharmacological target to physiological sterol transporter. Arteriosclerosis, thrombosis, and vascular biology 20061101
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Severe hepatic side effects of ezetimibe. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701
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Stress degradation studies on ezetimibe and development of a validated stability-indicating HPLC assay. Journal of pharmaceutical and biomedical analysis 20060607
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The role of the Niemann-Pick C1-like 1 protein in the subcellular transport of multiple lipids and their homeostasis. Current opinion in lipidology 20060601
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Comparison of the lipid-modifying efficacy and safety profiles of ezetimibe coadministered with simvastatin in older versus younger patients with primary hypercholesterolemia: a post Hoc analysis of subpopulations from three pooled clinical trials. Clinical therapeutics 20060601
Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies. Clinical therapeutics 20060601
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Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia. Arteriosclerosis, thrombosis, and vascular biology 20060501
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Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy. European heart journal 20060501
Effect of ezetimibe on low-density lipoprotein subtype distribution: results of a placebo-controlled, double-blind trial in patients treated by regular low-density lipoprotein apheresis and statins. Metabolism: clinical and experimental 20060501
Selective compensatory induction of hepatic HMG-CoA reductase in response to inhibition of cholesterol absorption. Experimental biology and medicine (Maywood, N.J.) 20060501
Type of preexisting lipid therapy predicts LDL-C response to ezetimibe. The Annals of pharmacotherapy 20060501
Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) Study. American heart journal 20060501
Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis. Gastroenterology 20060501
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A retrospective analysis of ezetimibe treatment in renal transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401
Drug utilization of ezetimibe in rehabilitation centres: registry analysis of factors influencing prescription and effectiveness of treatment. Current medical research and opinion 20060401
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Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake. The Journal of biological chemistry 20060310
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The second United Kingdom Heart and Renal Protection (UK-HARP-II) Study: a randomized controlled study of the biochemical safety and efficacy of adding ezetimibe to simvastatin as initial therapy among patients with CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060301
Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects. Journal of clinical pharmacology 20060301
Interaction of single-dose ezetimibe and steady-state cyclosporine in renal transplant patients. Journal of clinical pharmacology 20060301
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Evaluation of the potential for pharmacokinetic interaction between fenofibrate and ezetimibe: A phase I, open-label, multiple-dose, three-period crossover study in healthy subjects. Clinical therapeutics 20060301
Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination. Vascular health and risk management 20060301
Effect of silymarin and its polyphenolic fraction on cholesterol absorption in rats. Pharmacological research 20060201
Management of hyperlipidemia: new LDL-C targets for persons at high-risk for cardiovascular events. Medical science monitor : international medical journal of experimental and clinical research 20060201
Ezetimibe-associated myopathy in monotherapy and in combination with a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. The Canadian journal of cardiology 20060201
Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healthy subjects. International journal of clinical pharmacology and therapeutics 20060201
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Clinical inquiries. What are effective medication combinations for dyslipidemia? The Journal of family practice 20060101
Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101
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Effectiveness and tolerability of adding ezetimibe to niacin-based regimens for treatment of primary hyperlipidemia. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101
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Ezetimibe: a turbocharger for the race to reach NCEP LDL goals. South Dakota journal of medicine 20051001
[New results in the management of hypercholesterolemia]. Orvosi hetilap 20050925
Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption. Journal of medicinal chemistry 20050922
Development and validation of a reversed-phase HPLC method for the determination of ezetimibe in pharmaceutical dosage forms. Journal of pharmaceutical and biomedical analysis 20050915
Supratherapeutic response to ezetimibe administered with cyclosporine. The Annals of pharmacotherapy 20050901
Drug-induced acute autoimmune hepatitis during combination therapy with atorvastatin and ezetimibe. Annals of clinical biochemistry 20050901
[Innovative therapies in metabolic diseases: ezetimibe (Ezétrol), nicotinic acid (Niaspan), acids omega-3 (Omacor), rimonabant (Acomplia)]. Revue medicale de Bruxelles 20050901
Model-based development of gemcabene, a new lipid-altering agent. The AAPS journal 20050901
Pharmacologic options for aggressive low-density lipoprotein cholesterol lowering: benefits versus risks. The American journal of cardiology 20050822
Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8. Journal of lipid research 20050801
The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe. Current medical research and opinion 20050801
New insights into the genetic regulation of intestinal cholesterol absorption. Gastroenterology 20050801
Caveolin-1 is not required for murine intestinal cholesterol transport. The Journal of biological chemistry 20050729
Effect of co-administering ezetimibe with on-going simvastatin treatment on LDL-C goal attainment in hypercholesterolemic patients with coronary heart disease. International journal of cardiology 20050710
[Ezetimib and simvastatin. Cooperation at receptors of cholesterol metabolism]. MMW Fortschritte der Medizin 20050707
[Goal in hypercholesterolemia: lowering LDL cholesterol level by 50%]. MMW Fortschritte der Medizin 20050707
Cholesterol and plant sterol absorption: recent insights. The American journal of cardiology 20050704
In response to 'ezetimibe-induced hyperlipidaemia' case report. International journal of clinical practice 20050701
European Atherosclerosis Society--75th congress. IDrugs : the investigational drugs journal 20050701
Lipid altering-efficacy of ezetimibe co-administered with simvastatin compared with rosuvastatin: a meta-analysis of pooled data from 14 clinical trials. Current medical research and opinion 20050701
[Can we prevent the progression of aortic valve sclerosis and stenosis? The need for a prospective, randomized trial]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050701
[Lowering LDL cholesterol frequently does not adhere to guidelines. Also regard intestinal cholesterol source]. MMW Fortschritte der Medizin 20050609
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proceedings of the National Academy of Sciences of the United States of America 20050607
[Selective cholesterol absorption inhibition as a new prospect in treatment of hypercholesterolemia]. Medicina clinica 20050604
Worsening myopathy associated with ezetimibe in a patient with McArdle disease. QJM : monthly journal of the Association of Physicians 20050601
Efficacy and safety of ezetimibe co-administered with ongoing atorvastatin therapy in achieving low-density lipoprotein goal in patients with hypercholesterolemia and coronary heart disease. International journal of clinical practice 20050601
The use of ezetimibe in achieving low density lipoprotein lowering goals in clinical practice: position statement of a United Kingdom consensus panel. Current medical research and opinion 20050601
[Innovation instead of imitation -- news in drug therapy -- regarding the contribution in DMW 13/2005]. Deutsche medizinische Wochenschrift (1946) 20050520
Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans. Circulation 20050510
Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia. European heart journal 20050501
Management of mixed hyperlipidaemia. European heart journal 20050501
Effects of ezetimibe on plasma lipoproteins in severely hypercholesterolemic patients treated with regular LDL-apheresis and statins. Atherosclerosis 20050501
[Optimization of cholesterol reduction principles and clinical results of dual inhibition]. Der Internist 20050501
Getting there: statin plus ezetimibe for low-density lipoprotein cholesterol goals. Mayo Clinic proceedings 20050501
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. Mayo Clinic proceedings 20050501
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050501
Enhanced hypercholesterolemia therapy: the ezetimibe/simvastatin tablet. Drugs of today (Barcelona, Spain : 1998) 20050501
Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein. Biochimica et biophysica acta 20050415
Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption. Journal of lipid research 20050401
Effects of ezetimibe coadministered with simvastatin on C-reactive protein in a large cohort of hypercholesterolemic patients. Atherosclerosis 20050401
Projected coronary heart disease risk benefit with ezetimibe. Atherosclerosis 20050401
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics 20050401
[Innovation instead of imitation -- news in drug therapy]. Deutsche medizinische Wochenschrift (1946) 20050401
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050401
What is the best strategy for reducing deaths from heart disease? PLoS medicine 20050401
Ezetimibe-induced hyperlipidaemia. International journal of clinical practice. Supplement 20050401
LDL-C goal attainment with the addition of ezetimibe to ongoing simvastatin treatment in coronary heart disease patients with hypercholesterolemia. Current medical research and opinion 20050401
Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol. Biochemistry 20050322
Carbohydrate sulfonyl chlorides for simple, convenient access to glycoconjugates. Organic letters 20050317
Drugs for lipids. Treatment guidelines from the Medical Letter 20050301
Sterol transporters: targets of natural sterols and new lipid lowering drugs. Pharmacology & therapeutics 20050301
The dyslipidemia of diabetes mellitus: giving triglycerides and high-density lipoprotein cholesterol a higher priority? Endocrinology and metabolism clinics of North America 20050301
Drug treats two sources of cholesterol. The Nurse practitioner 20050301
Efficacy of ezetimibe in patients with statin-resistant and statin-intolerant familial hyperlipidaemias. Current medical research and opinion 20050301
[Approved indication for Ezetrol]. Lakartidningen 20050301
Management of dyslipidemia in women in the post-hormone therapy era. Journal of general internal medicine 20050301
Treatment of hypercholesterolemia with ezetimibe in the kidney transplant population. Transplantation proceedings 20050301
[Ezetimibe]. Revue de l'infirmiere 20050301
Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study. American heart journal 20050301
Ongoing clinical trials of the pleiotropic effects of statins. Vascular health and risk management 20050301
Help for your cholesterol when statins won't do. If you are one of the many, but also one of the few.. Harvard men's health watch 20050301
Cerebral cholesterol granuloma in homozygous familial hypercholesterolemia. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050215
[Ezetimibe and safety]. Ugeskrift for laeger 20050214
Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe. Clinical genetics 20050201
Rationale for combination therapy with statin drugs in the treatment of dyslipidemia. Current atherosclerosis reports 20050201
Zetia and Zocor: good together? New combo pill Vytorin may help some reach low LDL goals. Harvard health letter 20050201
Long-term safety and, tolerability profiles and lipid-modifying efficacy of ezetimibe coadministered with ongoing simvastatin treatment: a multicenter, randomized, double-blind, placebo-controlled, 48-week extension study. Clinical therapeutics 20050201
Comparison of ezetimibe plus simvastatin versus simvastatin monotherapy on atherosclerosis progression in familial hypercholesterolemia. Design and rationale of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial. American heart journal 20050201
Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane. The Journal of biological chemistry 20050114
[How sure is the combined lipid lowering?]. MMW Fortschritte der Medizin 20050113
[New therapeutic alternative to aggressive statin treatment]. Ugeskrift for laeger 20050110
Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats. Metabolism: clinical and experimental 20050101
An ezetimibe-policosanol combination has the potential to be an OTC agent that could dramatically lower LDL cholesterol without side effects. Medical hypotheses 20050101
Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review. Cardiovascular diabetology 20050101
Efficacy and safety of ezetimibe co-administered with simvastatin in thiazolidinedione-treated type 2 diabetic patients. Diabetes, obesity & metabolism 20050101
Ezetimibe plus simvastatin lowered lipid levels more than simvastatin monotherapy in primary hypercholesterolemia. ACP journal club 20050101
Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS. Lipids in health and disease 20050101
Simvastatin plus ezetimibe: combination therapy for the management of dyslipidaemia. Expert opinion on pharmacotherapy 20050101
Cost-effectiveness of statin monotherapy and combination therapy with ezetimibe. Connecticut medicine 20050101
Cholesterol. How low should we go? Saudi medical journal 20050101
Achieving synergy and improvements in cholesterol lowering. Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101
By the way, doctor. I take 20 mg of Lipitor and 10 mg of Zetia. My total cholesterol has declined from 177 to 145, my LDL from 133 to 93, but my 'good' HDL cholesterol also went down from 46 to 41. Would you consider my low HDL level a large risk factor? If so, is there a regimen that would increase it? Harvard health letter 20050101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050101
Ezetimibe and other azetidinone cholesterol absorption inhibitors. Current topics in medicinal chemistry 20050101
Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. Clinical pharmacokinetics 20050101
Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study. Current controlled trials in cardiovascular medicine 20050101
Statins research unfinished saga: desirability versus feasibility. Cardiovascular diabetology 20050101
Targets for low-density lipoprotein cholesterol levels in patients with stable coronary heart disease: where are we now after the 'treating to new targets' (TNT) trial? Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
Colesevelam HCl and ezetimibe combination therapy provides effective lipid-lowering in difficult-to-treat patients with hypercholesterolemia. American journal of therapeutics 20050101
Ezetimibe offers new opportunity to lower LDL-C to target levels. Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101
The SPHERE Study. Secondary prevention of heart disease in general practice: protocol of a randomised controlled trial of tailored practice and patient care plans with parallel qualitative, economic and policy analyses. [ISRCTN24081411]. Current controlled trials in cardiovascular medicine 20050101
NPC1L1 haplotype is associated with inter-individual variation in plasma low-density lipoprotein response to ezetimibe. Lipids in health and disease 20050101
Endothelial function in the forearm circulation of patients with the metabolic syndrome--effect of different lipid-lowering regimens. Cardiology 20050101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050101
[Ezetimib--inhibitor of cholesterol absorption: new perspectives in the treatment of dyslipidemia]. Terapevticheskii arkhiv 20050101
Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease. Lipids in health and disease 20050101
Focus on improving lipid-lowering efficacy at ESC - Stockholm, September 2005. Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101
LDL-C goal attainment with ezetimibe plus simvastatin coadministration vs atorvastatin or simvastatin monotherapy in patients at high risk of CHD. MedGenMed : Medscape general medicine 20050101
[Risk adapted therapy of vascular diseases--basic therapy of dys- and hyperlipoproteinemia]. Zeitschrift fur Kardiologie 20050101
The ABC of hepatic and intestinal cholesterol transport. Handbook of experimental pharmacology 20050101
[Coronary heart disease patient reaches LDL level of 100 mg/dl with atorvastatin: how do you continue treatment next year?]. MMW Fortschritte der Medizin 20041216
Phenotypic heterogeneity of sitosterolemia. Journal of lipid research 20041201
Lipids in health and disease. Biochemical Society transactions 20041201
Simvastatin: a review. Expert opinion on pharmacotherapy 20041201
Pharmacologic treatment of type 2 diabetic dyslipidemia. Pharmacotherapy 20041201
Lipid-lowering drugs. Nursing older people 20041201
Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men. Journal of women's health (2002) 20041201
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20041201
Autosomal recessive hypercholesterolaemia: normalization of plasma LDL cholesterol by ezetimibe in combination with statin treatment. Journal of internal medicine 20041101
Ezetimibe: a novel cholesterol-lowering agent that highlights novel physiologic pathways. Current cardiology reports 20041101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20041101
A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia. Clinical therapeutics 20041101
Lipid-lowering medications. Pediatric endocrinology reviews : PER 20041101
[Target values are more often attainable. Almost doubly so many patients with values under 100mg/dl]. MMW Fortschritte der Medizin 20041028
Ezetimibe and statin-associated myopathy. Annals of internal medicine 20041019
[The role of intestinal absorption blockade in hypercholesterolemia treatment]. Revista clinica espanola 20041001
Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage. Prescrire international 20041001
[Ezetimibe (Ezetrol): the statins' partner]. Revue medicale de Bruxelles 20041001
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20041001
[Ezetimib]. Deutsche medizinische Wochenschrift (1946) 20040924
Disruption of cholesterol homeostasis by plant sterols. The Journal of clinical investigation 20040915
Effectiveness and tolerability of ezetimibe add-on therapy to a bile acid resin-based regimen for hypercholesterolemia. The American journal of cardiology 20040915
Vytorin: a combination of ezetimibe and simvastatin. The Medical letter on drugs and therapeutics 20040913
Ezetimibe--a new cholesterol-lowering drug. Drug and therapeutics bulletin 20040901
Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome. Current medical research and opinion 20040901
Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers. Current medical research and opinion 20040901
Achieving lipoprotein goals in patients at high risk with severe hypercholesterolemia: efficacy and safety of ezetimibe co-administered with atorvastatin. American heart journal 20040901
Coadministration of multidrug therapy to achieve lipid goals. The Journal of the American Osteopathic Association 20040901
Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil. International journal of clinical pharmacology and therapeutics 20040901
Ezetimibe + simvastatin (Merck/Schering-Plough). Current opinion in investigational drugs (London, England : 2000) 20040901
New drugs. Canadian family physician Medecin de famille canadien 20040901
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20040901
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. The Journal of biological chemistry 20040806
Cholesterol absorption inhibitor Ezetimibe blocks uptake of oxidized LDL in human macrophages. Biochemical and biophysical research communications 20040806
Current management of severe homozygous hypercholesterolaemias. Current opinion in lipidology 20040801
Combination therapy in the management of complex dyslipidemias. Current opinion in lipidology 20040801
Treatment of hyperlipidemia in cardiac transplant recipients. American heart journal 20040801
Pharmacodynamic interaction between ezetimibe and rosuvastatin. Current medical research and opinion 20040801
Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe. Current medical research and opinion 20040801
Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia. International journal of clinical practice 20040801
[Ezetimib--a new possibility for combined therapy in hypercholesterolemia]. Vnitrni lekarstvi 20040801
New strategies in the treatment of dyslipidemia: do we know how? Seminars in vascular medicine 20040801
Statins as the cornerstone of drug therapy for dyslipidemia: monotherapy and combination therapy options. American heart journal 20040701
Beta-lactam cholesterol absorption inhibitors. Current medicinal chemistry 20040701
Long-term safety and tolerability profile of ezetimibe and atorvastatin coadministration therapy in patients with primary hypercholesterolaemia. International journal of clinical practice 20040701
The effects of ezetimibe on the LDL-cholesterol particle number. Cardiovascular drugs and therapy 20040701
Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals. The American journal of cardiology 20040615
Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia. The American journal of cardiology 20040615
[Can ezetimib also be used as a treatment for beta-sitosterol]. Deutsche medizinische Wochenschrift (1946) 20040611
Effects of ezetimibe on the pharmacodynamics and pharmacokinetics of lovastatin. Current medical research and opinion 20040601
New drug may help when statin response is low. Harvard heart letter : from Harvard Medical School 20040601
How doubling up drugs saves lives. Why doctors increasingly deploy an array of medications all at once. Heart advisor 20040601
Cholesterol metabolism and therapeutic targets: rationale for targeting multiple metabolic pathways. Clinical cardiology 20040601
Optimizing lipid lowering in patients at risk. Clinical cardiology 20040601
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20040601
[New combination therapy. Up to 60% lower LDL cholesterol level]. MMW Fortschritte der Medizin 20040506
Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial. Mayo Clinic proceedings 20040501
Statin pleiotropy: fact or fiction? American journal of critical care : an official publication, American Association of Critical-Care Nurses 20040501
Hypolipidemic treatment of heterozygous familial hypercholesterolemia: a lifelong challenge. Expert review of cardiovascular therapy 20040501
A statin for a patient with hyperlipidemia and hepatitis C? Postgraduate medicine 20040501
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20040501
Ezetimibe and statin-associated myopathy. Annals of internal medicine 20040420
[New treatment option for decreasing blood cholesterol level--clinical significance of inhibition of both, cholesterol absorption and synthesis]. Orvosi hetilap 20040411
On call. I'm a 63-year-old man with arthritis but no other conditions. My only medicines were Naprosyn and vitamins until my last annual checkup, when my cholesterol was high. My doctor gave me Zocor, which helped. But I developed muscle aches, so he switched me to Zetia. I feel fine again, but I'd like to know what you think. Harvard men's health watch 20040401
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20040401
[Ezetimibe (Ezetrol)]. Revue medicale de Liege 20040401
[Recommended LDL value far lower. How does one achieve this goal?]. MMW Fortschritte der Medizin 20040325
Stenosis and the drug-eluting stent. Circulation 20040323
Initial low-density lipoprotein response to statin therapy predicts subsequent low-density lipoprotein response to the addition of ezetimibe. The American journal of cardiology 20040315
Two more drugs for dyslipidemia. The American journal of cardiology 20040315
Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia. Circulation 20040302
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug metabolism and disposition: the biological fate of chemicals 20040301
Effectiveness of ezetimibe in clinical practice. The American journal of cardiology 20040301
Hypolipidemic therapy and cholesterol absorption. Current atherosclerosis reports 20040301
By the way, doctor. I've recently heard about a new cholesterol drug called Zetia. Does it work better than a statin? Harvard women's health watch 20040301
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20040301
Biomedicine. Will the real cholesterol transporter please stand up. Science (New York, N.Y.) 20040220
Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science (New York, N.Y.) 20040220
Homozygous hypercholesterolaemia and ezetimibe: a case report. Acta paediatrica (Oslo, Norway : 1992) 20040201
Lipids and atherosclerosis. Biochemistry and cell biology = Biochimie et biologie cellulaire 20040201
Lipid lowering activity of drugs affecting cholesterol absorption. Nutrition, metabolism, and cardiovascular diseases : NMCD 20040201
Homozygous familial hypercholesterolemia and its management. Seminars in vascular medicine 20040201
Role of selective cholesterol absorption inhibition in the management of dyslipidemia. Current atherosclerosis reports 20040101
The discovery of ezetimibe: a view from outside the receptor. Journal of medicinal chemistry 20040101
Optimizing LDL-C lowering with statins. American journal of therapeutics 20040101
Plant sterols: factors affecting their efficacy and safety as functional food ingredients. Lipids in health and disease 20040101
Treatment of hyperlipidemia in elderly persons with exercise training, nonpharmacologic therapy, and drug combinations. The American journal of geriatric cardiology 20040101
New developments in pharmacotherapy. Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20040101
Medical lipid-regulating therapy: current evidence, ongoing trials and future developments. Drugs 20040101
Safety and tolerability of ezetimibe. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20040101
[Blocking the absorption of cholesterol in the treatment of hyperlipidemia--old and new ways of treatment]. Duodecim; laaketieteellinen aikakauskirja 20040101
Preventing clinically evident coronary heart disease in the postmenopausal woman. Menopause (New York, N.Y.) 20040101
The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia. Lipids in health and disease 20040101
[Some new drugs: valdecoxib (Betra), voriconazole (Vfend), ezetimide (Ezetrol), teriparatide (Forsteo)]. Journal de pharmacie de Belgique 20040101
Ezetimibe/Simvastatin: a review of its use in the management of hypercholesterolemia. American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101
Comparative effects of lipid-lowering therapies. Progress in cardiovascular diseases 20040101
Lipid metabolism in zebrafish. Methods in cell biology 20040101
Efficacy and safety of coadministration of ezetimibe and statins in elderly patients with primary hypercholesterolaemia. Drugs & aging 20040101
Development and validation of a model to project the long-term benefit and cost of alternative lipid-lowering strategies in patients with hypercholesterolaemia. PharmacoEconomics 20040101
Cost-effectiveness of ezetimibe coadministration in statin-treated patients not at cholesterol goal: application to Germany, Spain and Norway. PharmacoEconomics 20040101
Effect of coadministration of ezetimibe and simvastatin on high-sensitivity C-reactive protein. The American journal of cardiology 20031215
[Hyperlipidemia: therapeutic principles in clinical practice]. Medizinische Klinik (Munich, Germany : 1983) 20031215
[Even at LDL cholesterol 100mg/dl. 'Every coronary disease patient has to receive a statin']. MMW Fortschritte der Medizin 20031204
Therapy and clinical trials: ezetimibe. Current opinion in lipidology 20031201
[Ezetimibe: from pharmacology to clinical trials]. Annales d'endocrinologie 20031201
Genetic regulation of cholesterol absorption and plasma plant sterol levels: commonalities and differences. Journal of lipid research 20031101
Newer pharmaceutical agents to treat lipid disorders. Current cardiology reports 20031101
New drugs for the treatment of hypercholesterolaemia. Expert opinion on investigational drugs 20031101
Pharmacotherapy for dyslipidaemia--current therapies and future agents. Expert opinion on pharmacotherapy 20031101
Ezetimibe: a selective cholesterol absorption inhibitor. Pharmacotherapy 20031101
Cholesterol absorption inhibitors: a closer look. Advance for nurse practitioners 20031101
Avoid the risks of mixed medications. How to minimize dangerous interactions with cardiovascular drugs. Heart advisor 20031101
Ezetimibe for hypercholesterolemia. American family physician 20031015
The antilipidemic effects of ezetimibe in patients with diabetes. Diabetes care 20031001
Ask the doctor. I am a 64-year-old woman with high cholesterol caused by bad genes (familial hypercholesterolemia). Without medication, my cholesterol is above 450 mg/dL. So I am taking high-dose Lipitor (80 mg/day), WelChol, and Zetia to lower my cholesterol. I sometimes have pain and stiffness in my knees, and my shoulder, elbow, and wrist joints, plus the muscles in between, are stiff in the morning and hurt during the day. Two years ago I was diagnosed with bursitis in my hips. Could these problems be f Harvard heart letter : from Harvard Medical School 20031001
Ezetimibe: a new addition to lipid-lowering therapy. International journal of clinical practice 20031001
Ezetimibe plus atorvastatin lowers cholesterol. The Journal of family practice 20030901
Lipid-lowering: can ezetimibe help close the treatment gap? Cleveland Clinic journal of medicine 20030901
Ezetimibe for lowering blood cholesterol. Issues in emerging health technologies 20030901
Pharmacology and therapeutics of ezetimibe (SCH 58235), a cholesterol-absorption inhibitor. Clinical therapeutics 20030901
The place of ezetimibe in clinical practice. Hospital medicine (London, England : 1998) 20030801
Achieving cholesterol goals. Current and future drug therapies. Postgraduate medicine 20030801
Efficacy of simvastatin and ezetimibe in treating hypercholesterolemia. Journal of the American College of Cardiology 20030716
Perspectives in cholesterol-lowering therapy: the role of ezetimibe, a new selective inhibitor of intestinal cholesterol absorption. Circulation 20030701
Therapeutic approaches to dyslipidemia in diabetes mellitus and metabolic syndrome. Current opinion in cardiology 20030701
Ezetimibe (Zetia): a new type of lipid-lowering agent. Proceedings (Baylor University. Medical Center) 20030701
Combination lipid-lowering therapy in diabetes. Current diabetes reports 20030601
Ezetimibe for management of hypercholesterolemia. The Annals of pharmacotherapy 20030601
Cholesterol absorption inhibitors: defining new options in lipid management. Clinical cardiology 20030601
Sterol absorption by the small intestine. Current opinion in lipidology 20030601
Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies. International journal of clinical practice 20030601
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20030601
[Coronary disease prevention: only the inhibition of inflammation is important. Why lower lipids, too?]. MMW Fortschritte der Medizin 20030522
Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Circulation 20030520
New lipid-lowering combo proves successful. Circulation 20030520
[Controlling LDL cholesterol from 2 sides. 'I have never seen such low LDL values']. MMW Fortschritte der Medizin 20030515
Familial hypercholesterolemia--improving treatment and meeting guidelines. International journal of cardiology 20030501
Treating dyslipidemic patients with lipid-modifying and combination therapies. Pharmacotherapy 20030501
Statins, super-statins and cholesterol absorption inhibitors. IDrugs : the investigational drugs journal 20030501
52nd Annual Scientific Session of the American College of Cardiology, Chicago, March 30-April 2, 2003. International journal of clinical practice 20030501
Three new drugs for hyperlipidemia. Connecticut medicine 20030501
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20030501
The future of lipid-lowering therapy: the big picture. The Netherlands journal of medicine 20030501
Ezetimibe: a novel option for lowering cholesterol. Expert review of cardiovascular therapy 20030501
Primary hypercholesterolemia: genetic causes and treatment of five monogenic disorders. Expert review of cardiovascular therapy 20030501
Dyslipidemia treatment: current considerations and unmet needs. Expert review of cardiovascular therapy 20030501
Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors. Bioorganic & medicinal chemistry 20030417
[Ezetimib as combination partner in hypercholesteremia. Lowering LDL beyond the effect of statins]. MMW Fortschritte der Medizin 20030417
New drug joins cholesterol-fighting arsenal. Mayo Clinic women's healthsource 20030401
Combined lipid lowering drug therapy for the effective treatment of hypercholesterolaemia. European heart journal 20030401
Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. European heart journal 20030401
Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia. European heart journal 20030401
Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats. British journal of pharmacology 20030401
Ezetimibe. Drugs of today (Barcelona, Spain : 1998) 20030401
Three new drugs for hyperlipidemia. The Medical letter on drugs and therapeutics 20030303
New lipid-modifying therapies. Expert opinion on investigational drugs 20030301
New cholesterol-lowering drug makes its mark. Mayo Clinic health letter (English ed.) 20030301
What future for combination therapies? International journal of clinical practice. Supplement 20030301
Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia. The American journal of cardiology 20030215
Fresh from the pipeline. Ezetimibe. Nature reviews. Drug discovery 20030201
Beyond statins. New drugs can work with, or in place of, cholesterol-lowering statins. Harvard heart letter : from Harvard Medical School 20030201
[Lowering cholesterol becomes easier. Combining instead of increasing dosage]. MMW Fortschritte der Medizin 20030123
Treating hypercholesterolemia: looking forward. Clinical cardiology 20030101
Combination therapy for dyslipidemia. The Journal of the American Osteopathic Association 20030101
A novel therapeutic approach to dyslipidemia. The Journal of the American Osteopathic Association 20030101
[The best of clinical pharmacology in 2002]. Archives des maladies du coeur et des vaisseaux 20030101
The intestinal absorption of biliary and dietary cholesterol as a drug target for lowering the plasma cholesterol level. Preventive cardiology 20030101
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