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Home > Imidazoles > 161796-78-7
161796-78-7 | 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
CAS No: 161796-78-7 Catalog No: AG001VVZ MDL No:MFCD07802816
Product Description
Catalog Number:
AG001VVZ
Chemical Name:
1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
CAS Number:
161796-78-7
Molecular Formula:
C17H19N3NaO3S
Molecular Weight:
368.4058
MDL Number:
MFCD07802816
IUPAC Name:
sodium;5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-3-ide
InChI:
InChI=1S/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3;/q-1;+1/t24-;/m0./s1
InChI Key:
RYXPMWYHEBGTRV-JIDHJSLPSA-N
SMILES:
COc1ccc2c(c1)[nH]c(n2)[S@@](=O)Cc1ncc(c(c1C)OC)C.[Na]
Properties
Complexity:
459
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
367.097g/mol
Formal Charge:
0
Heavy Atom Count:
25
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
367.399g/mol
Monoisotopic Mass:
367.097g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
81.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
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| Esomeprazole alone compared with esomeprazole plus aspirin for the treatment of aspirin-related peptic ulcers. | The American journal of gastroenterology 20120701 |
| Randomised clinical trial: esomeprazole for the prevention of nonsteroidal anti-inflammatory drug-related peptic ulcers in Japanese patients. | Alimentary pharmacology & therapeutics 20120701 |
| High-dose, ten-day esomeprazole, amoxicillin and metronidazole triple therapy achieves high Helicobacter pylori eradication rates. | Alimentary pharmacology & therapeutics 20120701 |
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| A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers. | Journal of the American College of Cardiology 20120403 |
| A comparison of the acid-inhibitory effects of esomeprazole and rabeprazole in relation to pharmacokinetics and CYP2C19 polymorphism. | Alimentary pharmacology & therapeutics 20120401 |
| Doxycycline-based quadruple regimen versus routine quadruple regimen for rescue eradication of Helicobacter pylori: an open-label control study in Chinese patients. | Singapore medical journal 20120401 |
| Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. | The American journal of gastroenterology 20120301 |
| Esomeprazole relieves upper gastrointestinal symptoms in high-risk and average-risk NSAID users in daily clinical practice: results from an open-label study. | European journal of gastroenterology & hepatology 20120301 |
| Comparison of levofloxacin-containing sequential and standard triple therapies for the eradication of Helicobacter pylori. | European journal of internal medicine 20120301 |
| Acetylsalicylic acid/esomeprazole fixed-dose combination. | Drugs & aging 20120301 |
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| Agranulocytosis induced by proton pump inhibitors. | Journal of clinical gastroenterology 20120101 |
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| Omeprazole- and esomeprazole-associated hypomagnesaemia: data mining of the public version of the FDA Adverse Event Reporting System. | International journal of medical sciences 20120101 |
| A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials. | Annals of medicine 20111201 |
| Randomized trial on 14 versus 7 days of esomeprazole, moxifloxacin, and amoxicillin for second-line or rescue treatment of Helicobacter pylori infection. | Helicobacter 20111201 |
| Impact of a fixed-dose combination of naproxen and esomeprazole magnesium on serum thromboxane B2 inhibition by low-dose aspirin over 5 days in healthy adults: a phase I, randomized, double-blind, placebo-controlled, noninferiority trial. | Clinical therapeutics 20111201 |
| Ventricular bigeminy associated with voriconazole, methadone and esomeprazole. | International journal of clinical pharmacy 20111201 |
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| Doubling the dose of clopidogrel restores the loss of antiplatelet effect induced by esomeprazole. | Thrombosis research 20111101 |
| The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel. | Drug metabolism and disposition: the biological fate of chemicals 20111101 |
| Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations. | Clinical pharmacokinetics 20111101 |
| Effect of esomeprazole versus famotidine on platelet inhibition by clopidogrel: a double-blind, randomized trial. | American heart journal 20111101 |
| [Esomeprazole-induced subacute cutaneous lupus erythematosus]. | Actas dermo-sifiliograficas 20111001 |
| Chronic cough and esomeprazole: a double-blind placebo-controlled parallel study. | Respirology (Carlton, Vic.) 20111001 |
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| Whole-cell oxidation of omeprazole sulfide to enantiopure esomeprazole with Lysinibacillus sp. B71. | Bioresource technology 20110901 |
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| Supplementation of Los Angeles classification with esophageal mucosa index of hemoglobin can predict the treatment response of erosive reflux esophagitis. | Surgical endoscopy 20110801 |
| Influence of esomeprazole on hypoglycemic activity of oral antidiabetic agents in rats and rabbits. | Molecular and cellular biochemistry 20110801 |
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| Race affects healing of erosive oesophagitis in patients treated with proton pump inhibitors. | Alimentary pharmacology & therapeutics 20110801 |
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| Treatment of non-erosive reflux disease with a proton pump inhibitor in Chinese patients: a randomized controlled trial. | Journal of gastroenterology 20110701 |
| Measurement of mucosal conductivity by MII is a potential marker of mucosal integrity restored in infants on acid-suppression therapy. | Journal of pediatric gastroenterology and nutrition 20110701 |
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| Impact of acid suppression on upper gastrointestinal pH and motility. | Digestive diseases and sciences 20110601 |
| Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials. | Current medical research and opinion 20110601 |
| Intravenous esomeprazole: a pharmacoeconomic profile of its use in the prevention of recurrent peptic ulcer bleeding. | PharmacoEconomics 20110601 |
| Effects of different proton pump inhibitors on cardiac contractility in isolated human failing myocardium. | The Journal of cardiovascular surgery 20110601 |
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| Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction. | Clinical cardiology 20100301 |
| Counselling by primary care physicians may help patients with heartburn-predominant uninvestigated dyspepsia. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20100301 |
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| Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: a wireless pH metry analysis. | Journal of gastroenterology and hepatology 20100101 |
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| Differential effects of esomeprazole on the antiplatelet activity of clopidogrel in healthy individuals and patients after coronary stent implantation. | The Journal of international medical research 20100101 |
| Clarithromycin-amoxycillin-containing triple therapy: a valid empirical first-line treatment for Helicobacter pylori eradication in Hong Kong? | Helicobacter 20091201 |
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| [Effect of esomeprazole upon intestinal mucosal damage following traumatic brain injury in rats]. | Zhonghua yi xue za zhi 20091103 |
| Quantification of dental erosions in patients with GERD using optical coherence tomography before and after double-blind, randomized treatment with esomeprazole or placebo. | The American journal of gastroenterology 20091101 |
| Effects of asymptomatic proximal and distal gastroesophageal reflux on asthma severity. | American journal of respiratory and critical care medicine 20091101 |
| Moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate. | Helicobacter 20091001 |
| Systematic review: standard- and double-dose proton pump inhibitors for the healing of severe erosive oesophagitis -- a mixed treatment comparison of randomized controlled trials. | Alimentary pharmacology & therapeutics 20090915 |
| Furazolidone, co-amoxiclav, colloidal bismuth subcitrate, and esomeprazole for patients who failed to eradicate Helicobacter pylori with triple therapy. | Digestive diseases and sciences 20090901 |
| Seven-day intravenous low-dose omeprazole infusion reduces peptic ulcer rebleeding for patients with comorbidities. | Gastrointestinal endoscopy 20090901 |
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| Evaluation of the pharmacokinetic interaction between esomeprazole (40 mg) and acetylsalicylic acid (325 mg) in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20090901 |
| Subcutaneous infusion of esomeprazole in elderly patients in palliative care: a report of two cases. | Journal of the American Geriatrics Society 20090901 |
| Off-label use of medicines in children: can available evidence avoid useless paediatric trials? The case of proton pump inhibitors for the treatment of gastroesophageal reflux disease. | European journal of clinical pharmacology 20090801 |
| Pharmacodynamics and systemic exposure of esomeprazole in preterm infants and term neonates with gastroesophageal reflux disease. | The Journal of pediatrics 20090801 |
| Esomeprazole for asthma. | The New England journal of medicine 20090709 |
| Esomeprazole for asthma. | The New England journal of medicine 20090709 |
| Esomeprazole for asthma. | The New England journal of medicine 20090709 |
| Second-line levofloxacin-based triple schemes for Helicobacter pylori eradication. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090701 |
| Transmucosal gastric leak induced by proton pump inhibitors. | Digestive diseases and sciences 20090701 |
| Microscopic colitis associated with omeprazole and esomeprazole exposure. | Journal of clinical gastroenterology 20090701 |
| Proton-pump inhibitor therapy induces acid-related symptoms in healthy volunteers after withdrawal of therapy. | Gastroenterology 20090701 |
| H. pylori eradication prevents the progression of gastric intestinal metaplasia in reflux esophagitis patients using long-term esomeprazole. | The American journal of gastroenterology 20090701 |
| Clinical trial: intragastric acid control in patients who have Barrett's oesophagus--comparison of once- and twice-daily regimens of esomeprazole and lansoprazole. | Alimentary pharmacology & therapeutics 20090701 |
| Clinical course of laryngo-respiratory symptoms in gastro-oesophageal reflux disease during routine care--a 5-year follow-up. | Alimentary pharmacology & therapeutics 20090601 |
| Characterization of mechanisms underlying the effects of esomeprazole on the impairment of gastric ulcer healing with addition of NSAID treatment. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090601 |
| Clinical trial: factors associated with freedom from relapse of heartburn in patients with healed reflux oesophagitis--results from the maintenance phase of the EXPO study. | Alimentary pharmacology & therapeutics 20090601 |
| Clinical trial: the treatment of gastro-oesophageal reflux disease in primary care--prospective randomized comparison of rabeprazole 20 mg with esomeprazole 20 and 40 mg. | Alimentary pharmacology & therapeutics 20090501 |
| Clinical trial: factors associated with resolution of heartburn in patients with reflux oesophagitis--results from the EXPO study. | Alimentary pharmacology & therapeutics 20090501 |
| Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial. | The Journal of antimicrobial chemotherapy 20090501 |
| Hypomagnesaemia due to use of proton pump inhibitors--a review. | The Netherlands journal of medicine 20090501 |
| Effect of proton pump inhibition on the gastric volume: assessed by magnetic resonance imaging. | Alimentary pharmacology & therapeutics 20090415 |
| Efficacy of esomeprazole for treatment of poorly controlled asthma. | The New England journal of medicine 20090409 |
| Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: a randomized trial. | Annals of internal medicine 20090407 |
| Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel. | Thrombosis and haemostasis 20090401 |
| Is body mass index really the most important factor determining the healing of reflux esophagitis by esomeprazole? | The American journal of gastroenterology 20090301 |
| Seven-day PPI-triple therapy with levofloxacin is very effective for Helicobacter pylori eradication. | The Netherlands journal of medicine 20090301 |
| Oral or intravenous proton pump inhibitor in patients with peptic ulcer bleeding after successful endoscopic epinephrine injection. | British journal of clinical pharmacology 20090301 |
| Comparative study of omeprazole, lansoprazole, pantoprazole and esomeprazole for symptom relief in patients with reflux esophagitis. | World journal of gastroenterology 20090227 |
| Nefopam hydrochloride compatibility and stability with selected proton pump inhibitors in bionolyte G5 injection for intravenous infusion. | Journal of clinical pharmacy and therapeutics 20090201 |
| Esomeprazole: a proton pump inhibitor. | Expert review of gastroenterology & hepatology 20090201 |
| After move to tier 3, Nexium scripts fall 25%. | Managed care (Langhorne, Pa.) 20090201 |
| Release of regulatory gut peptides somatostatin, neurotensin and vasoactive intestinal peptide by acid and hyperosmolal solutions in the intestine in conscious rats. | Regulatory peptides 20090108 |
| A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children. | Acta paediatrica (Oslo, Norway : 1992) 20090101 |
| Optimal dose regimens of esomeprazole for gastric acid suppression with minimal influence of the CYP2C19 polymorphism. | European journal of clinical pharmacology 20090101 |
| Cost analysis of long-term treatment of patients with symptomatic gastroesophageal reflux disease (GERD) with esomeprazole on-demand treatment or esomeprazole continuous treatment: an open, randomized, multicenter study in Switzerland. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101 |
| Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel. | American heart journal 20090101 |
| The Australian rise of esomeprazole-was expenditure on samples a contributor? | Pharmacoepidemiology and drug safety 20090101 |
| Proton-pump inhibitor utilization associated with the change to nonpreferred formulary status for esomeprazole in the TRICARE formulary. | Journal of managed care pharmacy : JMCP 20090101 |
| Chemoprevention of oesophageal cancer and the AspECT trial. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20090101 |
| Alternative vs. conventional treatment given on-demand for gastroesophageal reflux disease: a randomised controlled trial. | BMC complementary and alternative medicine 20090101 |
| [Stevens-Johnson syndrome and toxic hepatitis due to esomeprazole]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101 |
| Improving quality of magnetic resonance cholangiopancreaticography: esomeprazole versus ranitidine. | Hepato-gastroenterology 20090101 |
| High-dose esomeprazole for treatment of symptomatic refractory gastroesophageal reflux disease--a prospective pH-metry/impedance-controlled study. | Digestion 20090101 |
| Esomeprazole for the management of upper gastrointestinal symptoms in patients who require NSAIDs: a review of the NASA and SPACE double-blind, placebo-controlled studies. | Clinical drug investigation 20090101 |
| Patient satisfaction with switching to esomeprazole from existing proton pump inhibitor therapy for gastro-oesophageal reflux disease: an observational, multicentre study. | Clinical drug investigation 20090101 |
| [Esomeprazole based triple therapy for the eradication of helicobacter pylori in patients with non-ulcer dyspepsia]. | Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20090101 |
| Effects of esomeprazole treatment for gastroesophageal reflux disease on quality of life in 12- to 17-year-old adolescents: an international health outcomes study. | BMC gastroenterology 20090101 |
| [Omeprazol and ezomeprazol pharmacokinetics, duration of antisecretory effect, and reasons for their probable changes in duodenal ulcer]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101 |
| Peptic ulcer bleeding following therapeutic endoscopy: a new indication for intravenous esomeprazole. | Reviews in gastroenterological disorders 20090101 |
| [Usage of Nexium (ezomeprazole) at children with acid depended inflammatory diseases of upper gastrointestinal tract]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101 |
| [Comparative study of esomeprazole and omeprazole using for initialism therapy for elderly-senile and young-adulthood patients with GERD]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101 |
| Moxifloxacine plus amoxicillin and ranitidine bismuth citrate or esomeprazole triple therapies for Helicobacter pylori infection. | Digestive diseases and sciences 20081201 |
| A glass of water immediately increases gastric pH in healthy subjects. | Digestive diseases and sciences 20081201 |
| Esomeprazole induces upper gastrointestinal tract transmucosal permeability increase. | Alimentary pharmacology & therapeutics 20081201 |
| Effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter pylori eradication: a meta-analysis. | Helicobacter 20081201 |
| The effectiveness of esomeprazole 40 mg in patients with persistent symptoms of gastro-oesophageal reflux disease following treatment with a full dose proton pump inhibitor. | International journal of clinical practice 20081201 |
| [Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?]. | Annales d'endocrinologie 20081101 |
| Bravo capsule system optimizes intragastric pH monitoring over prolonged time: effects of ghrelin on gastric acid and hormone secretion in the rat. | World journal of gastroenterology 20081028 |
| [General practitioners' management of gastroesophageal reflux in France in 2005: a pharmacoeconomic study]. | Presse medicale (Paris, France : 1983) 20081001 |
| Effects of esomeprazole on glutathione levels and mitochondrial oxidative phosphorylation in the gastric mucosa of rats treated with indomethacin. | Naunyn-Schmiedeberg's archives of pharmacology 20081001 |
| Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin. | The American journal of gastroenterology 20081001 |
| Meta-analysis: high-dose proton pump inhibitors vs. standard dose in triple therapy for Helicobacter pylori eradication. | Alimentary pharmacology & therapeutics 20081001 |
| Medical or surgical management of GERD patients with Barrett's esophagus: the LOTUS trial 3-year experience. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20081001 |
| Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial. | Gut 20080901 |
| Physical and chemical stability of esomeprazole sodium solutions. | The Annals of pharmacotherapy 20080901 |
| Body mass index can determine the healing of reflux esophagitis with Los Angeles Grades C and D by esomeprazole. | The American journal of gastroenterology 20080901 |
| Double-blind, placebo-controlled trial with esomeprazole for symptoms and signs associated with laryngopharyngeal reflux. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080901 |
| Preparation of esomeprazole zinc solid dispersion and study on its pharmacokinetics. | International journal of pharmaceutics 20080806 |
| Effect of the CYP2C19 polymorphism on the eradication rate of Helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage. | Journal of gastroenterology and hepatology 20080801 |
| [Comparison of Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia and peptic ulcer diseases according to proton pump inhibitors]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20080801 |
| Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z. | Alimentary pharmacology & therapeutics 20080701 |
| Changes in gene expression of gastric mucosa during therapeutic acid inhibition. | European journal of gastroenterology & hepatology 20080701 |
| [Preparation and dissolution in vitro of esomeprazole zinc solid dispersion]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080701 |
| Effect of esomeprazole triple therapy on eradication rates of Helicobacter pylori, gastric ulcer healing and prevention of relapse in gastric ulcer patients. | European journal of gastroenterology & hepatology 20080601 |
| Esomeprazole in acute and maintenance treatment of reflux oesophagitis: a multicentre prospective study. | Advances in therapy 20080601 |
| [Diagnosis of gastroesophageal reflux disease-related noncardiac chest pain]. | Zhonghua yi xue za zhi 20080527 |
| The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption. | Thyroid : official journal of the American Thyroid Association 20080501 |
| FDA approves nexium for use in children ages 1-11 years. | Gastroenterology 20080501 |
| Safety and tolerability of esomeprazole in children with gastroesophageal reflux disease. | Journal of pediatric gastroenterology and nutrition 20080501 |
| Preoperative administration of esomeprazole has no influence on frequency of refluxes. | Journal of clinical anesthesia 20080501 |
| Intravenous esomeprazole for prevention of peptic ulcer re-bleeding: rationale/design of Peptic Ulcer Bleed study. | Alimentary pharmacology & therapeutics 20080401 |
| Correlation between oesophageal acid exposure and dyspeptic symptoms in patients with nonerosive reflux disease. | European journal of gastroenterology & hepatology 20080401 |
| Comparison of esomeprazole enteric-coated capsules vs esomeprazole magnesium in the treatment of active duodenal ulcer: a randomized, double-blind, controlled study. | World journal of gastroenterology 20080328 |
| Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults. | Alimentary pharmacology & therapeutics 20080315 |
| The anti-secretory and anti-ulcer activities of esomeprazole in comparison with omeprazole in the stomach of rats and rabbits. | Molecular and cellular biochemistry 20080201 |
| One-week once-daily triple therapy with esomeprazole, moxifloxacin, and rifabutin for eradication of persistent Helicobacter pylori resistant to both metronidazole and clarithromycin. | Helicobacter 20080201 |
| In-practice predictors of response to proton pump inhibitor therapy in primary care patients with dyspepsia in an Asian population. | Journal of clinical gastroenterology 20080201 |
| Management strategy for patients with gastroesophageal reflux disease: a comparison between empirical treatment with esomeprazole and endoscopy-oriented treatment. | The American journal of gastroenterology 20080201 |
| A randomized, comparative trial of a potassium-competitive acid blocker (AZD0865) and esomeprazole for the treatment of patients with nonerosive reflux disease. | The American journal of gastroenterology 20080101 |
| Validation of a four-graded scale for severity of heartburn in patients with symptoms of gastroesophageal reflux disease. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101 |
| Clinical efficacy of esomeprazole in the prevention and healing of gastrointestinal toxicity associated with NSAIDs in elderly patients. | Drugs & aging 20080101 |
| Effect of proton-pump inhibitor treatment on symptoms and quality of life in GERD patients depends on the symptom-reflux association. | Journal of clinical gastroenterology 20080101 |
| Safety profile of esomeprazole: results of a prescription-event monitoring study of 11 595 patients in England. | Drug safety 20080101 |
| Stereoselective disposition of proton pump inhibitors. | Clinical drug investigation 20080101 |
| Esomeprazole: in gastroesophageal reflux disease in children and adolescents. | Paediatric drugs 20080101 |
| Effect of increasing esomeprazole and pantoprazole doses on acid control in patients with symptoms of gastro-oesophageal reflux disease: a randomized, dose-response study. | Clinical drug investigation 20080101 |
| Occurrence of community-acquired respiratory tract infection in patients receiving esomeprazole: retrospective analysis of adverse events in 31 clinical trials. | Drug safety 20080101 |
| Esomeprazole: a review of its use in the management of gastric acid-related diseases in adults. | Drugs 20080101 |
| Effect of acid suppression on gastric myoelectrical activity in GERD. | Hepato-gastroenterology 20080101 |
| Esomeprazole reduces gastroesophageal reflux after beer consumption in healthy volunteers. | Scandinavian journal of gastroenterology 20080101 |
| Effect of proton pump inhibitors on gastric juice volume, gastric pH and gastric intramucosal pH in critically ill patients : a randomized, double-blind, placebo-controlled study. | Clinical drug investigation 20080101 |
| The effect of acid suppression on sleep and cardiac autonomic regulation in GERD. | Hepato-gastroenterology 20080101 |
| Esomeprazole prevents aspirin-induced ulcers. | Medscape journal of medicine 20080101 |
| Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. | The American journal of gastroenterology 20071201 |
| Water load test before and after PPI therapy in patients with gastro-oesophageal reflux disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20071201 |
| A randomized, comparative study of three doses of AZD0865 and esomeprazole for healing of reflux esophagitis. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071201 |
| Second-line treatment for Helicobacter pylori infection: 10-day moxifloxacin-based triple therapy versus 2-week quadruple therapy. | Helicobacter 20071201 |
| Rabeprazole- versus esomeprazole-based eradication regimens for H. pylori infection. | Helicobacter 20071201 |
| Double-dose, new-generation proton pump inhibitors do not improve Helicobacter pylori eradication rate. | Helicobacter 20071201 |
| Esomeprazole-induced DRESS syndrome. Studies of cross-reactivity among proton-pump inhibitor drugs. | Allergy 20071101 |
| The impact of body mass index on the application of on-demand therapy for Los Angeles grades A and B reflux esophagitis. | The American journal of gastroenterology 20071101 |
| Safety and symptom improvement with esomeprazole in adolescents with gastroesophageal reflux disease. | Journal of pediatric gastroenterology and nutrition 20071101 |
| Pharmacokinetics and acid-suppressive effects of esomeprazole in infants 1-24 months old with symptoms of gastroesophageal reflux disease. | Journal of pediatric gastroenterology and nutrition 20071101 |
| Impact of treatment of gastroesophageal reflux on obstructive sleep apnea-hypopnea syndrome. | The Annals of otology, rhinology, and laryngology 20071101 |
| Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy - a randomized study comparing ranitidine with esomeprazole. | Alimentary pharmacology & therapeutics 20071015 |
| [Repeated dual-probe pH monitoring as a diagnostic tool to control therapy for laryngopharyngeal reflux]. | HNO 20071001 |
| Clinical trial: levofloxacin-based quadruple therapy was inferior to traditional quadruple therapy in the treatment of resistant Helicobacter pylori infection. | Alimentary pharmacology & therapeutics 20071001 |
| Effect of timing of dosing in relation to food intake on the pharmacokinetics of esomeprazole. | British journal of clinical pharmacology 20070901 |
| High-dose versus low-dose esomeprazole-based triple therapy for Helicobacter pylori infection. | European journal of clinical investigation 20070901 |
| One-week acid suppression trial in uninvestigated dyspepsia patients with epigastric pain or burning to predict response to 8 weeks' treatment with esomeprazole: a randomized, placebo-controlled study. | Alimentary pharmacology & therapeutics 20070901 |
| Randomized-controlled trial of esomeprazole in functional dyspepsia patients with epigastric pain or burning: does a 1-week trial of acid suppression predict symptom response? | Alimentary pharmacology & therapeutics 20070901 |
| Distension during gastroesophageal reflux: effects of acid inhibition and correlation with symptoms. | American journal of physiology. Gastrointestinal and liver physiology 20070801 |
| Recent advances in chirally pure proton pump inhibitors. | Journal of the Indian Medical Association 20070801 |
| Effect of baseline symptom severity on patient-reported outcomes in gastroesophageal reflux disease. | European journal of gastroenterology & hepatology 20070701 |
| A clinical trial comparing pantoprazole and esomeprazole to explore the concept of achieving 'complete remission' in gastro-oesophageal reflux disease. | Alimentary pharmacology & therapeutics 20070615 |
| Soraprazan: setting new standards in inhibition of gastric acid secretion. | The Journal of pharmacology and experimental therapeutics 20070601 |
| One week of esomeprazole triple therapy vs 1 week of omeprazole triple therapy plus 3 weeks of omeprazole for duodenal ulcer healding in Helicobacter pylori-positive patients. | Digestive diseases and sciences 20070601 |
| Tegaserod for dyspepsia and reflux symptoms in patients with chronic constipation: an exploratory open-label study. | European journal of clinical pharmacology 20070601 |
| Severe systemic adverse reaction to proton pump inhibitors in an infant. | Pediatric pulmonology 20070601 |
| Effect of esomeprazole and rabeprazole on intragastric pH in healthy Chinese: an open, randomized crossover trial. | Journal of gastroenterology and hepatology 20070601 |
| [Protonic pump inhibitors in kidney transplant patients: efficacy and safety]. | Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20070601 |
| [Different courses of esomeprazole-based triple therapy for Helicobactor pylori infection in children]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070601 |
| Suppression of gastric acid with intravenous esomeprazole and omeprazole: results of 3 studies in healthy subjects. | International journal of clinical pharmacology and therapeutics 20070601 |
| Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. | Lancet (London, England) 20070512 |
| Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics. | The American journal of gastroenterology 20070501 |
| Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire. | Alimentary pharmacology & therapeutics 20070501 |
| Esomeprazole: prevention and treatment of NSAID-induced symptoms and ulcers. | Expert opinion on pharmacotherapy 20070501 |
| Determination of esomeprazole and its two main metabolites in human, rat and dog plasma by liquid chromatography with tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401 |
| Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs. | Alimentary pharmacology & therapeutics 20070401 |
| Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. | Medical science monitor : international medical journal of experimental and clinical research 20070401 |
| A new esomeprazole packet (sachet) formulation for suspension: in vitro characteristics and comparative pharmacokinetics versus intact capsules/tablets in healthy volunteers. | Clinical therapeutics 20070401 |
| [Clinical pharmacological aspects of the proton pump inhibitor therapy: importance of pharmacogenetic differences in the clinical practice]. | Orvosi hetilap 20070325 |
| Efficacy of pantoprazole 20 mg daily compared with esomeprazole 20 mg daily in the maintenance of healed gastroesophageal reflux disease: a randomized, double-blind comparative trial - the EMANCIPATE study. | European journal of gastroenterology & hepatology 20070301 |
| Relationship between intragastric acid control and healing status in the treatment of moderate to severe erosive oesophagitis. | Alimentary pharmacology & therapeutics 20070301 |
| Effect of antireflux treatment on asthma exacerbations in nonatopic children. | Journal of pediatric gastroenterology and nutrition 20070301 |
| Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis. | The American journal of geriatric pharmacotherapy 20070301 |
| Combined analysis of three crossover clinical pharmacology studies of effects of rabeprazole and esomeprazole on 24-h intragastric pH in healthy volunteers. | Alimentary pharmacology & therapeutics 20070215 |
| [Changes of intercellular spaces of esophageal epithelium in patients with gastroesophageal reflux disease before and after esomeprazole treatment]. | Zhonghua yi xue za zhi 20070206 |
| Does esomeprazole prevent post-operative nausea and vomiting? | Acta anaesthesiologica Scandinavica 20070201 |
| Effect of intravenous application of esomeprazole 40 mg versus pantoprazole 40 mg on 24-hour intragastric pH in healthy adults. | European journal of gastroenterology & hepatology 20070201 |
| Efficacy of once-daily esomeprazole treatment in patients with laryngopharyngeal reflux evaluated by 24-hour pH monitoring. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070201 |
| Acidic and non-acidic reflux during sleep under conditions of powerful acid suppression. | Chest 20070201 |
| Acid control with esomeprazole and lansoprazole: a comparative dose-response study. | Scandinavian journal of gastroenterology 20070201 |
| [Proton pump inhibitors in developmental period medicine]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070201 |
| Comparison of the effects of immediate-release omeprazole oral suspension, delayed-release lansoprazole capsules and delayed-release esomeprazole capsules on nocturnal gastric acidity after bedtime dosing in patients with night-time GERD symptoms. | Alimentary pharmacology & therapeutics 20070115 |
| Effect of oral esomeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. | Journal of gastroenterology and hepatology 20070101 |
| Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies. | Arthritis research & therapy 20070101 |
| Novel measurement of rapid treatment success with ReQuest: first and sustained symptom relief as outcome parameters in patients with endoscopy-negative GERD receiving 20 mg pantoprazole or 20 mg esomeprazole. | Digestion 20070101 |
| Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse. | Digestion 20070101 |
| Bioequivalence study of a sustained release fixed dose combination capsule containing esomeprazole and domperidone in healthy subjects. | Arzneimittel-Forschung 20070101 |
| Symptom resolution does not predict healing of erosive oesophagitis in Chinese. | Digestion 20070101 |
| The concept of complete remission of gastro-oesophageal reflux disease : comparative efficacy of pantoprazole and esomeprazole using the ReQuest questionnaire. | Clinical drug investigation 20070101 |
| Potential options to optimize therapy of gastroesophageal reflux disease with proton pump inhibitors. | Digestion 20070101 |
| Effect of intravenous esomeprazole 40 mg and pantoprazole 40 mg on intragastric pH in healthy subjects. A prospective, open, randomised, two-way cross-over comparative study. | Arzneimittel-Forschung 20070101 |
| [Efficiency and safety of the intravenous application of esomeprazole (nexium - Astra Zeneca) in high risk patients subjected to mechanic ventilation]. | Khirurgiia 20070101 |
| Esomeprazole versus other proton pump inhibitors in erosive esophagitis: a meta-analysis of randomized clinical trials. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061201 |
| An in vitro comparison of different providers to deliver four proton pump inhibitor products through a feeding tube. | Alimentary pharmacology & therapeutics 20061201 |
| [Antiplatelet therapy after aspirin-induced upper gastrointestinal bleeding]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20061102 |
| Prospective follow-up data from the ProGERD study suggest that GERD is not a categorial disease. | The American journal of gastroenterology 20061101 |
| Randomized comparison of two rescue therapies for Helicobacter pylori infection. | European journal of clinical investigation 20061101 |
| Pharmacokinetic properties of esomeprazole in children aged 1 to 11 years with symptoms of gastroesophageal reflux disease: a randomized, open-label study. | Clinical therapeutics 20061101 |
| Delivery of esomeprazole magnesium through nasogastric and gastrostomy tubes using an oral liquid vehicle as a suspending agent in vitro. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061001 |
| Esomeprazole 40 mg once a day in patients with functional dyspepsia: the randomized, placebo-controlled 'ENTER' trial. | The American journal of gastroenterology 20060901 |
| Gastric and esophageal pH in patients with Barrett's esophagus treated with three esomeprazole dosages: a randomized, double-blind, crossover trial. | The American journal of gastroenterology 20060901 |
| Effects of single doses of rabeprazole 20 mg and esomeprazole 40 mg on 24-h intragastric pH in healthy subjects. | European journal of clinical pharmacology 20060901 |
| Systematic review: proton pump inhibitors (PPIs) for the healing of reflux oesophagitis - a comparison of esomeprazole with other PPIs. | Alimentary pharmacology & therapeutics 20060901 |
| Sequential therapy using high-dose esomeprazole-amoxicillin followed by gatifloxacin for Helicobacter pylori infection. | Alimentary pharmacology & therapeutics 20060901 |
| Treatment of chronic posterior laryngitis with esomeprazole. | The Laryngoscope 20060901 |
| Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradication. | The American journal of gastroenterology 20060901 |
| Esomeprazole versus pantoprazole for healing erosive oesophagitis. | Collegium antropologicum 20060901 |
| Ablation of nonneoplastic Barrett's mucosa using argon plasma coagulation with concomitant esomeprazole therapy (APBANEX): a prospective multicenter evaluation. | The American journal of gastroenterology 20060801 |
| Esomeprazole-based 1-week triple therapy directed by susceptibility testing for eradication of Helicobacter pylori infection in children. | Journal of pediatric gastroenterology and nutrition 20060801 |
| Role of the preliminary susceptibility testing for initial and after failed therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and esomeprazole. | Helicobacter 20060801 |
| Randomized trial of rifabutin-based triple therapy and high-dose dual therapy for rescue treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin. | Alimentary pharmacology & therapeutics 20060715 |
| Maintenance of healed erosive esophagitis: a randomized six-month comparison of esomeprazole twenty milligrams with lansoprazole fifteen milligrams. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701 |
| Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060701 |
| Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem. | International journal of clinical pharmacology and therapeutics 20060701 |
| Review article: the opportunities and benefits of extended acid suppression. | Alimentary pharmacology & therapeutics 20060601 |
| Myopathy including polymyositis: a likely class adverse effect of proton pump inhibitors? | European journal of clinical pharmacology 20060601 |
| Eradication of Helicobacter pylori and dosages of esomeprazole. | The American journal of gastroenterology 20060601 |
| Effects of esomeprazole 40 mg twice daily on asthma: a randomized placebo-controlled trial. | American journal of respiratory and critical care medicine 20060515 |
| Coadministration of esomeprazole with fosamprenavir has no impact on steady-state plasma amprenavir pharmacokinetics. | Journal of acquired immune deficiency syndromes (1999) 20060501 |
| A multicenter, randomized, double-blind, 8-week comparative trial of standard doses of esomeprazole (40 mg) and omeprazole (20 mg) for the treatment of erosive esophagitis. | Digestive diseases and sciences 20060501 |
| A multicenter, randomized, double-blind, 8-week comparative trial of low-dose esomeprazole (20 mg) and standard-dose omeprazole (20 mg) in patients with erosive esophagitis. | Digestive diseases and sciences 20060501 |
| Intragastric acidity after switching from 5-day treatment with intravenous pantoprazole 40 mg/d to 5-day treatment with oral esomeprazole 40 mg/d or pantoprazole 40 mg/d: an open-label crossover study in healthy adult volunteers. | Clinical therapeutics 20060501 |
| Intragastric acid control in non-steroidal anti-inflammatory drug users: comparison of esomeprazole, lansoprazole and pantoprazole. | Alimentary pharmacology & therapeutics 20060415 |
| Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study. | Alimentary pharmacology & therapeutics 20060415 |
| Esomeprazole for the prevention of postoperative nausea and vomiting. A randomized, placebo-controlled trial. | European journal of anaesthesiology 20060401 |
| Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors. | The American journal of gastroenterology 20060401 |
| Effects of esomeprazole on the pharmacokinetics of atazanavir and fosamprenavir in a patient with human immunodeficiency virus infection. | Pharmacotherapy 20060401 |
| The effects of esomeprazole combined with aspirin or rofecoxib on prostaglandin E2 production in patients with Barrett's oesophagus. | Alimentary pharmacology & therapeutics 20060401 |
| A COX-2-specific inhibitor plus a proton-pump inhibitor: is this a reasonable approach to reduction in NSAIDs' GI toxicity? | The American journal of gastroenterology 20060401 |
| [Long-term treatment of patients with symptomatic gastroesophageal reflux disease comparing costs and efficacy over 6 months of treatment with Nexium On-Demand Treatment or Nexium continuous treatment. An open, randomised multi-center study]. | Praxis 20060329 |
| Studies on drug interactions between esomeprazole, amoxicillin and clarithromycin in healthy subjects. | International journal of clinical pharmacology and therapeutics 20060301 |
| Pharmacokinetic properties of esomeprazole in adolescent patients aged 12 to 17 years with symptoms of gastroesophageal reflux disease: A randomized, open-label study. | Clinical therapeutics 20060301 |
| Validation of a symptom diary for patients with gastro-oesophageal reflux disease. | Alimentary pharmacology & therapeutics 20060215 |
| Sensitive quantification of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202 |
| Intra-oesophageal acid suppression in complicated gastro-oesophageal reflux disease: esomeprazole versus lansoprazole. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060201 |
| Upper gastrointestinal haemorrhage complicating antiplatelet treatment with aspirin and/or clopidogrel: where we are now? | Platelets 20060201 |
| 7-day triple therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and high-dose esomeprazole in patients with known antimicrobial sensitivity. | Helicobacter 20060201 |
| Efficacy of moxifloxacin-based triple therapy as second-line treatment for Helicobacter pylori infection. | Helicobacter 20060201 |
| Twice-a-day quadruple therapy for eradication of Helicobacter pylori in the elderly. | Helicobacter 20060201 |
| Treatment of chronic posterior laryngitis with esomeprazole. | The Laryngoscope 20060201 |
| Helicobacter pylori eradication with either 7-day or 10-day triple therapies, and with a 10-day sequential regimen. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20060201 |
| Histological effects of esomeprazole therapy on the squamous epithelium of the distal oesophagus. | Alimentary pharmacology & therapeutics 20060115 |
| Long-term management of patients with symptoms of gastro-oesophageal reflux disease -- a Norwegian randomised prospective study comparing the effects of esomeprazole and ranitidine treatment strategies on health-related quality of life in a general practitioners setting. | International journal of clinical practice 20060101 |
| Treatment of patients with persistent heartburn symptoms: a double-blind, randomized trial. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060101 |
| Intravenous proton pump inhibitors. | Reviews in gastroenterological disorders 20060101 |
| [Economic evaluation of the treatment with aspirin plus esomeprazole compared to clopidogrel in gastrointestinal bleeding prevention]. | Gaceta sanitaria 20060101 |
| Rifaximin-based regimens for eradication of Helicobacter pylori: a pilot study. | Digestive diseases (Basel, Switzerland) 20060101 |
| A meta-analysis: comparison of esomeprazole and other proton pump inhibitors in eradicating Helicobacter pylori. | Digestion 20060101 |
| Atypical symptoms of GORD in Belgium: epidemiological features, current management and open label treatment with 40 mg esomeprazole for one month. | Acta gastro-enterologica Belgica 20060101 |
| Pharmacokinetic drug interaction profiles of proton pump inhibitors. | Drug safety 20060101 |
| Comparative study of modified-release clarithromycin and immediate-release clarithromycin in the treatment of Helicobacter pylori-associated peptic ulcer disease. | Hepato-gastroenterology 20060101 |
| Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse. | Digestion 20060101 |
| Diagnostic value of the Reflux Disease Questionnaire in general practice. | Digestion 20060101 |
| Esomeprazole therapy for gastric acid hypersecretion in children with cystinosis. | Pediatric nephrology (Berlin, Germany) 20051201 |
| [ASS or clopidogrel plus esomeprazole after bleeding from an ulcer]. | Der Internist 20051201 |
| Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: evidence from clinical and pharmacokinetic data. | Clinical pharmacology and therapeutics 20051201 |
| Pharmacokinetics of esomeprazole following varying intravenous administration rates. | Basic & clinical pharmacology & toxicology 20051201 |
| Healing of gastric ulcers with esomeprazole versus ranitidine in patients who continued to receive NSAID therapy: a randomized trial. | The American journal of gastroenterology 20051201 |
| Esomeprazole 20 mg vs. pantoprazole 20 mg for maintenance therapy of healed erosive oesophagitis: results from the EXPO study. | Alimentary pharmacology & therapeutics 20051101 |
| Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-oesophageal reflux disease. | Alimentary pharmacology & therapeutics 20051101 |
| Gastric fundal polyps with cellular atypia in a patient using esomeprazole (Nexium). | Digestive diseases and sciences 20051101 |
| A prospective randomized trial of esomeprazole- versus pantoprazole-based triple therapy for Helicobacter pylori eradication. | The American journal of gastroenterology 20051101 |
| [Cytolytic hepatitis and esomeprazole during chemotherapy]. | Presse medicale (Paris, France : 1983) 20051008 |
| Comment: esomeprazole-induced central fever with severe myalgia. | The Annals of pharmacotherapy 20051001 |
| Cost-effectiveness comparison of current proton-pump inhibitors to treat gastro-oesophageal reflux disease in the UK. | Current medical research and opinion 20051001 |
| Effect of esomeprazole on nighttime heartburn and sleep quality in patients with GERD: a randomized, placebo-controlled trial. | The American journal of gastroenterology 20050901 |
| Esomeprazole-based therapy in Helicobacter pylori eradication: any effect by increasing the dose of esomeprazole or prolonging the treatment? | The American journal of gastroenterology 20050901 |
| Effect on intragastric pH of a PPI with a prolonged plasma half-life: comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteers. | The American journal of gastroenterology 20050901 |
| Quality of life in acute and maintenance treatment of non-erosive and mild erosive gastro-oesophageal reflux disease. | Alimentary pharmacology & therapeutics 20050815 |
| Long-term omeprazole and esomeprazole treatment does not significantly increase gastric epithelial cell proliferation and epithelial growth factor receptor expression and has no effect on apoptosis and p53 expression. | World journal of gastroenterology 20050814 |
| Comparative study and optimisation of the administration mode of three proton pump inhibitors by nasogastric tube. | International journal of pharmaceutics 20050811 |
| One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050801 |
| Daily treatment with esomeprazole is superior to that taken on-demand for maintenance of healed erosive oesophagitis. | Alimentary pharmacology & therapeutics 20050801 |
| [Comparison of esomeprazole- and omeprazole-based triple therapy regimens for duodenal ulcer with Helicobacter pylori infection]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801 |
| A comparison of esomeprazole and lansoprazole for control of intragastric pH in patients with symptoms of gastro-oesophageal reflux disease. | Alimentary pharmacology & therapeutics 20050715 |
| Laryngopharyngeal reflux: prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response. | The Laryngoscope 20050701 |
| Prognostic influence of Barrett's oesophagus and Helicobacter pylori infection on healing of erosive gastro-oesophageal reflux disease (GORD) and symptom resolution in non-erosive GORD: report from the ProGORD study. | Gut 20050601 |
| Six-month management of patients following treatment for gastroesophageal reflux disease symptoms -- a Norwegian randomized, prospective study comparing the costs and effectiveness of esomeprazole and ranitidine treatment strategies in a general medical practitioners setting. | International journal of clinical practice 20050601 |
| A randomised prospective study comparing the effectiveness of esomeprazole treatment strategies in clinical practice for 6 months in the management of patients with symptoms of gastroesophageal reflux disease. | International journal of clinical practice 20050601 |
| Empirical treatment for the management of patients presenting with uninvestigated reflux symptoms: a prospective study in an Asian primary care population. | Alimentary pharmacology & therapeutics 20050601 |
| [Cacosmia related to therapy with esomeprazole]. | La Revue de medecine interne 20050601 |
| Influence of CYP2C19 pharmacogenetic polymorphism on proton pump inhibitor-based therapies. | Drug metabolism and pharmacokinetics 20050601 |
| Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: a randomized, double-blind study in urban Asia. | World journal of gastroenterology 20050528 |
| Esomeprazole tablet vs omeprazole capsule in treating erosive esophagitis. | World journal of gastroenterology 20050528 |
| Lexiva: blood levels not lowered when taken simultaneously with Nexium. | AIDS treatment news 20050527 |
| Moxifloxacin-based strategies for first-line treatment of Helicobacter pylori infection. | Alimentary pharmacology & therapeutics 20050515 |
| Improvements with esomeprazole in patients with upper gastrointestinal symptoms taking non-steroidal antiinflammatory drugs, including selective COX-2 inhibitors. | The American journal of gastroenterology 20050501 |
| Intragastric acidity during treatment with esomeprazole 40 mg twice daily or pantoprazole 40 mg twice daily--a randomized, two-way crossover study. | Alimentary pharmacology & therapeutics 20050415 |
| [Rapidity of pain relief, medication requirement and patient satisfaction with reflux treatment in the physician's office]. | MMW Fortschritte der Medizin 20050407 |
| Hyponatremia with consciousness disturbance associated with esomeprazole. | The Annals of pharmacotherapy 20050401 |
| Esomeprazole-induced central fever with severe myalgia. | The Annals of pharmacotherapy 20050401 |
| Efficacy and tolerability of rifampicin-based rescue therapy for Helicobacter pylori eradication failure in peptic ulcer disease. | Digestive diseases and sciences 20050401 |
| High eradication rates of Helicobacter pylori infection with first- and second-line combination of esomeprazole, tetracycline, and metronidazole in patients allergic to penicillin. | Digestive diseases and sciences 20050401 |
| A randomized comparative study of esomeprazole 40 mg versus pantoprazole 40 mg for healing erosive oesophagitis: the EXPO study. | Alimentary pharmacology & therapeutics 20050315 |
| Acute interstitial nephritis secondary to esomeprazole. | The Medical journal of Australia 20050307 |
| A comparative study of the early effects of tenatoprazole 40 mg and esomeprazole 40 mg on intragastric pH in healthy volunteers. | Alimentary pharmacology & therapeutics 20050301 |
| Esomeprazole in the treatment of patients with heartburn and other upper gastrointestinal symptoms, referred to primary care -- results of the in-practice evaluation program in Romania. | Romanian journal of gastroenterology 20050301 |
| Efficacy of esomeprazole 40 mg vs. lansoprazole 30 mg for healing moderate to severe erosive oesophagitis. | Alimentary pharmacology & therapeutics 20050215 |
| Intravenous esomeprazole (40 mg and 20 mg) inhibits gastric acid secretion as effectively as oral esomeprazole: results of two randomized clinical studies. | European journal of gastroenterology & hepatology 20050201 |
| A randomized controlled trial of equivalence between pantoprazole and esomeprazole that does not have the power to conclude. | Journal of clinical gastroenterology 20050201 |
| Esomeprazole 40 mg twice daily in triple therapy and the efficacy of Helicobacter pylori eradication related to CYP2C19 metabolism. | Alimentary pharmacology & therapeutics 20050201 |
| [Gastroesophageal reflux disease refractory to esomeprazole]. | Gastroenterologia y hepatologia 20050201 |
| Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. | The New England journal of medicine 20050120 |
| A pharmacokinetic study comparing single and repeated oral doses of 20 mg and 40 mg omeprazole and its two optical isomers, S-omeprazole (esomeprazole) and R-omeprazole, in healthy subjects. | European journal of clinical pharmacology 20050101 |
| Night-time gastro-oesophageal reflux disease: prevalence, hazards, and management. | European journal of gastroenterology & hepatology 20050101 |
| The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole. | Health and quality of life outcomes 20050101 |
| Esomeprazole MUPS 40 mg tablets and esomeprazole MUPS 40 mg tablets encapsulated in hard gelatine are bioequivalent. | International journal of clinical pharmacology and therapeutics 20050101 |
| Effects of esomeprazole magnesium on nonsteroidal anti-inflammatory drug gastropathy. | Digestive diseases and sciences 20050101 |
| The influence of gastroesophageal reflux disease and its treatment on asthmatic cough. | Lung 20050101 |
| Novel measurement of rapid treatment success with ReQuest: first and sustained symptom relief as outcome parameters in patients with endoscopy-negative GERD receiving 20 mg pantoprazole or 20 mg esomeprazole. | Digestion 20050101 |
| Lansoprazole oro-dispersible tablet : pharmacokinetics and therapeutic use in acid-related disorders. | Drugs 20050101 |
| The impact of illness in patients with moderate to severe gastro-esophageal reflux disease. | BMC gastroenterology 20050101 |
| Comparison of the efficacy of 1-day high-dose quadruple therapy versus 7-day triple therapy for treatment of Helicobacter pylori infection. | Chinese journal of digestive diseases 20050101 |
| What is potent acid inhibition, and how can it be achieved? | Drugs 20050101 |
| Optimising acid inhibition treatment. | Drugs 20050101 |
| Efficacy and safety of intravenous esomeprazole in gastro-esophageal reflux disease and erosive esophagitis in Indian patients. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20050101 |
| Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. | Journal of the National Cancer Institute 20041117 |
| Esomeprazole 40 mg i.v. provides faster and more effective intragastric acid control than pantoprazole 40 mg i.v.: results of a randomized study. | Alimentary pharmacology & therapeutics 20041115 |
| Review article: pH, healing and symptom relief with rabeprazole treatment in acid-related disorders. | Alimentary pharmacology & therapeutics 20041101 |
| Sleep dysfunction in patients with gastro-oesophageal reflux disease: prevalence and response to GERD therapy, a pilot study. | Alimentary pharmacology & therapeutics 20041101 |
| Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux. | The Journal of laryngology and otology 20041101 |
| Esomeprazole 40 mg provides more effective intragastric acid control than lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg and rabeprazole 20 mg in patients with gastro-oesophageal reflux symptoms. | European journal of clinical pharmacology 20041001 |
| Review article: is stringent control of gastric pH useful and practical in GERD? | Alimentary pharmacology & therapeutics 20041001 |
| Esomeprazole 20 mg on-demand is more acceptable to patients than continuous lansoprazole 15 mg in the long-term maintenance of endoscopy-negative gastro-oesophageal reflux patients: the COMMAND Study. | Alimentary pharmacology & therapeutics 20040915 |
| Therapeutic choices in reflux disease: defining the criteria for selecting a proton pump inhibitor. | The American journal of medicine 20040906 |
| Effect of the H, K-ATPase inhibitor, esomeprazole magnesium, on gut total antioxidant capacity in mice. | The Journal of nutritional biochemistry 20040901 |
| Intragastric acid suppression and pharmacokinetics of twice-daily esomeprazole: a randomized, three-way crossover study. | Alimentary pharmacology & therapeutics 20040815 |
| The role of acid suppression in patients with endoscopy-negative reflux disease: the effect of treatment with esomeprazole or omeprazole. | Alimentary pharmacology & therapeutics 20040815 |
| Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. | Drug metabolism and disposition: the biological fate of chemicals 20040801 |
| Symptom response and healing of erosive esophagitis with proton-pump inhibitors in patients with Helicobacter pylori infection. | The American journal of gastroenterology 20040801 |
| Esomeprazole versus omeprazole for the eradication of Helicobacter pylori infection: results of a randomized controlled study. | Journal of clinical gastroenterology 20040701 |
| Masking of 13C urea breath test by proton pump inhibitors is dependent on type of medication: comparison between omeprazole, pantoprazole, lansoprazole and esomeprazole. | Alimentary pharmacology & therapeutics 20040701 |
| [New-generation proton pump inhibitors: progress in the treatment of peptic acid diseases?]. | Presse medicale (Paris, France : 1983) 20040619 |
| Risk factors of gastroesophageal reflux disease: methodology and first epidemiological results of the ProGERD study. | Journal of clinical epidemiology 20040601 |
| Effect of splitting the dose of esomeprazole on gastric acidity and nocturnal acid breakthrough. | Alimentary pharmacology & therapeutics 20040515 |
| Effect of proton pump inhibitors and antacid therapy on 13C urea breath tests and stool test for Helicobacter pylori infection. | The American journal of gastroenterology 20040501 |
| Induction of testosterone metabolism by esomeprazole in a CYP2C19*2 heterozygote. | The American journal of the medical sciences 20040501 |
| Costs and efficacy of three different esomeprazole treatment strategies for long-term management of gastro-oesophageal reflux symptoms in primary care. | Alimentary pharmacology & therapeutics 20040415 |
| 40 mg pantoprazole and 40 mg esomeprazole are equivalent in the healing of esophageal lesions and relief from gastroesophageal reflux disease-related symptoms. | Journal of clinical gastroenterology 20040401 |
| Esomeprazole-based therapy in Helicobacter pylori eradication: a meta-analysis. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040401 |
| Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers. | Alimentary pharmacology & therapeutics 20040315 |
| Cost-minimization analysis of treatment of gastroesophageal reflux disease. Implications of varying holding time on conclusions. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201 |
| Intravenous esomeprazole. | Drugs 20040101 |
| Single-isomer drugs: true therapeutic advances. | Clinical pharmacokinetics 20040101 |
| Single-enantiomer drugs: elegant science, disappointing effects. | Clinical pharmacokinetics 20040101 |
| Efficacy of esomeprazole in patients with acid-peptic disorders. | Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20040101 |
| Minimal change esophagitis: prospective comparison of endoscopic and histological markers between patients with non-erosive reflux disease and normal controls using magnifying endoscopy. | Digestive diseases (Basel, Switzerland) 20040101 |
| [Experience of application of Esomeprazole in patients with chronic hepatic diseases associated with acid-dependent diseases]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101 |
| Esomeprazole 40 mg administered intravenously has similar safety and efficacy profiles to the oral formulation in patients with erosive esophagitis. | Digestion 20040101 |
| Helicobacter pylori infection in Greenlandic patients with dyspepsia. | International journal of circumpolar health 20040101 |
| Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study. | The American journal of gastroenterology 20031201 |
| Esomeprazole resolves chronic heartburn in patients without erosive oesophagitis. | Alimentary pharmacology & therapeutics 20031101 |
| Quality of life in relation to symptoms in patients with gastro-oesophageal reflux disease-- an analysis based on the ProGERD initiative. | Alimentary pharmacology & therapeutics 20031015 |
| Esomeprazole-based one-week triple therapy with clarithromycin and metronidazole is effective in eradicating Helicobacter pylori in the absence of antimicrobial resistance. | Alimentary pharmacology & therapeutics 20031015 |
| Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects. | Alimentary pharmacology & therapeutics 20031001 |
| Esomeprazole administered through a nasogastric tube provides bioavailability similar to oral dosing. | Alimentary pharmacology & therapeutics 20030915 |
| Once-daily pantoprazole 40 mg and esomeprazole 40 mg have equivalent overall efficacy in relieving GERD-related symptoms. | Alimentary pharmacology & therapeutics 20030915 |
| Meta-analysis: comparative efficacy of different proton-pump inhibitors in triple therapy for Helicobacter pylori eradication. | Alimentary pharmacology & therapeutics 20030915 |
| On-demand therapy for Los Angeles grade A and B reflux esophagitis: esomeprazole versus omeprazole. | Journal of the Formosan Medical Association = Taiwan yi zhi 20030901 |
| Intra-oesophageal pH profiles and pharmacokinetics of pantoprazole and esomeprazole: a crossover study in patients with gastro-oesophageal reflux disease. | European journal of gastroenterology & hepatology 20030701 |
| A review of the clinical and economic impact of using esomeprazole or lansoprazole for the treatment of erosive esophagitis. | Clinical therapeutics 20030701 |
| Prilosec, nexium and stereoisomers. | The Medical letter on drugs and therapeutics 20030623 |
| [All proton pump inhibitors are equally efficacious in standard dosages]. | Lakartidningen 20030619 |
| Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. | The Annals of pharmacotherapy 20030601 |
| One-week triple therapy with esomeprazole, clarithromycin and metronidazole provides effective eradication of Helicobacter pylori infection. | Alimentary pharmacology & therapeutics 20030601 |
| Effects of 6-12 months of esomeprazole treatment on the gastric mucosa. | The American journal of gastroenterology 20030601 |
| Stability of esomeprazole capsule contents after in vitro suspension in common soft foods and beverages. | Pharmacotherapy 20030601 |
| [In-vitro activity of rabeprazole, lansoprazole, and esomeprazole against Helicobacter pylori]. | Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20030601 |
| [Impact of 24-hour intraesophageal pH monitoring with 2 channels in the diagnosis of reflux-induced otolaryngologic disorders]. | Laryngo- rhino- otologie 20030501 |
| [Nexium and Losec are equally good]. | Lakartidningen 20030424 |
| [Nexium is not better than Losec]. | Lakartidningen 20030417 |
| Empiric esomeprazole in the treatment of laryngopharyngeal reflux. | The Laryngoscope 20030401 |
| Symptom-relieving effect of esomeprazole 40 mg daily in patients with heartburn. | Scandinavian journal of gastroenterology 20030401 |
| One-week esomeprazole treatment: an effective confirmatory test in patients with suspected gastroesophageal reflux disease. | Scandinavian journal of gastroenterology 20030401 |
| Synthesis or rupture: duration of acid inhibition by proton pump inhibitors. | Drugs of today (Barcelona, Spain : 1998) 20030301 |
| Review article: Esomeprazole--enhanced bio-availability, specificity for the proton pump and inhibition of acid secretion. | Alimentary pharmacology & therapeutics 20030215 |
| [Exaggerated interaction claims. With esomeprazole the data corroborate safety]. | MMW Fortschritte der Medizin 20030206 |
| Review of esomeprazole in the treatment of acid disorders. | Expert opinion on pharmacotherapy 20030201 |
| Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results. | Alimentary pharmacology & therapeutics 20030201 |
| Antimicrobial activity of esomeprazole versus omeprazole against Helicobacter pylori. | The Journal of antimicrobial chemotherapy 20030201 |
| A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole. | Nature reviews. Drug discovery 20030201 |
| Review article: esomeprazole--the first proton pump inhibitor to be developed as an isomer. | Alimentary pharmacology & therapeutics 20030201 |
| Review article: pharmacology of esomeprazole and comparisons with omeprazole. | Alimentary pharmacology & therapeutics 20030201 |
| Review article: gastric acidity--comparison of esomeprazole with other proton pump inhibitors. | Alimentary pharmacology & therapeutics 20030201 |
| Review article: initial therapy of reflux disease with esomeprazole. | Alimentary pharmacology & therapeutics 20030201 |
| Review article: esomeprazole, 40 mg once daily, compared with lansoprazole, 30 mg once daily, in healing and symptom resolution of erosive oesophagitis. | Alimentary pharmacology & therapeutics 20030201 |
| Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results. | Alimentary pharmacology & therapeutics 20030201 |
| Pantoprazole: an update of its pharmacological properties and therapeutic use in the management of acid-related disorders. | Drugs 20030101 |
| [Esomeprazole in treating duodenal ulcer in various modes of anti-Helicobacter therapy]. | Terapevticheskii arkhiv 20030101 |
| [Use of omeprazole and esomeprazole in patients suffering from bronchial asthma with associated gastroesophageal reflux disease]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101 |
| An overview of proton pump inhibitors. | Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20030101 |
| Efficacy of esomeprazole in controlling reflux symptoms, intraesophageal, and intragastric pH in patients with Barrett's esophagus. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20030101 |
| [Experience with the application of the preparation nexium in patients by using the BioEnterics Intragastgric Balloon]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101 |
| Esomeprazole 40 mg provides improved intragastric acid control as compared with lansoprazole 30 mg and rabeprazole 20 mg in healthy volunteers. | Digestion 20030101 |
| [Comparative effectiveness of the antisecretory action of rabeprazole and esomeprazole in people with rapid metabolism of proton pump inhibitors]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101 |
| Clinical and endoscopic evaluation of gastroesophageal reflux disease in patients successfully treated with esomeprazole. | Arquivos de gastroenterologia 20030101 |
| Treatment and management of Helicobacter pylori infection. | Current gastroenterology reports 20021201 |
| On-demand proton pump inhibitor therapy in patients with gastro-oesophageal reflux disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20021201 |
| Delivery of esomeprazole magnesium enteric-coated pellets through small caliber and standard nasogastric tubes and gastrostomy tubes in vitro. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101 |
| The effect of the area under the plasma concentration vs time curve and the maximum plasma concentration of esomeprazole on intragastric pH. | European journal of clinical pharmacology 20021001 |
| An open non-comparative clinical study for the evaluation of safety and efficacy of esomeprazole in patients of reflux oesophagitis in Indian population. | Journal of the Indian Medical Association 20021001 |
| [Pharma clinics medication of the month. Esomeprazole]. | Revue medicale de Liege 20020901 |
| Esomeprazole 40 mg and 20 mg is efficacious in the long-term management of patients with endoscopy-negative gastro-oesophageal reflux disease: a placebo-controlled trial of on-demand therapy for 6 months. | European journal of gastroenterology & hepatology 20020801 |
| One week regimen of esomeprazole based triple therapy is sufficient for duodenal ulcer healing and Helicobacter pylori eradication in patients with duodenal ulcer disease. | European journal of gastroenterology & hepatology 20020801 |
| Esomeprazole: a clinical review. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020715 |
| Proton pump inhibitors: an update. | American family physician 20020715 |
| Review article: esomeprazole in the treatment of Helicobacter pylori. | Alimentary pharmacology & therapeutics 20020701 |
| Effects of rabeprazole, 20 mg, or esomeprazole, 20 mg, on 24-h intragastric pH and serum gastrin in healthy subjects. | Alimentary pharmacology & therapeutics 20020701 |
| Pharmacologic management of gastroesophageal reflux disease. | Current gastroenterology reports 20020601 |
| Views on esomeprazole-based triple therapy to treat duodenal ulcer disease and Helicobacter pylori infection. | European journal of gastroenterology & hepatology 20020601 |
| Pharmacokinetic study of esomeprazole in patients with hepatic impairment. | European journal of gastroenterology & hepatology 20020501 |
| Effect of esomeprazole 40 mg vs omeprazole 40 mg on 24-hour intragastric pH in patients with symptoms of gastroesophageal reflux disease. | Digestive diseases and sciences 20020501 |
| Esomeprazole for acid peptic disorders. | The Annals of pharmacotherapy 20020401 |
| Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis. | The American journal of gastroenterology 20020301 |
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