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CAS No: 161262-45-9 Catalog No: AG001SAC MDL No:
Title | Journal |
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Therapeutic efficacy of platelet components treated with amotosalen and ultraviolet A pathogen inactivation method: results of a meta-analysis of randomized controlled trials. | Vox sanguinis 20121101 |
Pathogen inactivation technology applied to a blood component collected from an asymptomatic carrier of Leishmania infantum: a case report. | Vox sanguinis 20121101 |
Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis. | Clinical and vaccine immunology : CVI 20120401 |
Bacterial contamination of platelet components: potential solutions to prevent transfusion-related sepsis. | Expert review of hematology 20111001 |
[Pathogen inactivation in platelet concentrates: the French experience]. | Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20110801 |
A multi-centre study of therapeutic efficacy and safety of platelet components treated with amotosalen and ultraviolet A pathogen inactivation stored for 6 or 7 d prior to transfusion. | British journal of haematology 20110501 |
[Photochemical inactivation of pathogens in platelets and plasma: five years of clinical use in routine and hemovigilance. Towards a change of paradigm in transfusion safety]. | Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20110401 |
A comparison of methods of pathogen inactivation of FFP. | Vox sanguinis 20110201 |
In vitro assessment of apheresis and pooled buffy coat platelet components suspended in plasma and SSP+ photochemically treated with amotosalen and UVA for pathogen inactivation (INTERCEPT Blood Systemâ„¢). | Vox sanguinis 20110201 |
The extent of amotosalen photodegradation during photochemical treatment of platelet components correlates with the level of pathogen inactivation. | Transfusion 20110101 |
Monitoring photochemical pathogen inactivation treatment using amotosalen and ultraviolet-A light: evaluation of an indicator label. | Vox sanguinis 20101101 |
An active hemovigilance program characterizing the safety profile of 7483 transfusions with plasma components prepared with amotosalen and UVA photochemical treatment. | Transfusion 20100601 |
INTERCEPT plasma: comparability with conventional fresh-frozen plasma based on coagulation function--an in vitro analysis. | Vox sanguinis 20100101 |
Functional characteristics of apheresis-derived platelets treated with ultraviolet light combined with either amotosalen-HCl (S-59) or riboflavin (vitamin B2) for pathogen-reduction. | Vox sanguinis 20090701 |
Assessment of safety in neonates for transfusion of platelets and plasma prepared with amotosalen photochemical pathogen inactivation treatment by a 1-month intravenous toxicity study in neonatal rats. | Transfusion 20090501 |
Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax. | Infection and immunity 20090401 |
Evaluation of in vitro storage properties of prestorage pooled whole blood-derived platelets suspended in 100 percent plasma and treated with amotosalen and long-wavelength ultraviolet light. | Transfusion 20090401 |
Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation. | Analytical chemistry 20081115 |
Quantitative and qualitative analysis of proteins in fresh frozen plasma obtained from whole blood donations and prepared with two photochemical treatments. | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20081001 |
Photochemical inactivation with amotosalen and long-wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components. | Transfusion 20080801 |
Effects of Mirasol PRT treatment on storage lesion development in plasma-stored apheresis-derived platelets compared to untreated and irradiated units. | Transfusion 20080801 |
An active haemovigilance programme characterizing the safety profile of 7437 platelet transfusions prepared with amotosalen photochemical treatment. | Vox sanguinis 20080501 |
Photochemical treatment of plasma with amotosalen and UVA light: process validation in three European blood centers. | Transfusion 20080401 |
Coagulation function in fresh-frozen plasma prepared with two photochemical treatment methods: methylene blue and amotosalen. | Transfusion 20080101 |
Pathogen inactivation: a new paradigm for preventing transfusion-transmitted infections. | American journal of clinical pathology 20071201 |
The pathogen reduction treatment of platelets with S-59 HCl (Amotosalen) plus ultraviolet A light: genotoxicity profile and hazard assessment. | Mutation research 20070615 |
Inactivation of parvovirus B19 in human platelet concentrates by treatment with amotosalen and ultraviolet A illumination. | Transfusion 20070601 |
Leukoreduced buffy coat-derived platelet concentrates photochemically treated with amotosalen HCl and ultraviolet A light stored up to 7 days: assessment of hemostatic function under flow conditions. | Transfusion 20070401 |
The efficacy of photochemical treatment with amotosalen HCl and ultraviolet A (INTERCEPT) for inactivation of Trypanosoma cruzi in pooled buffy-coat platelets. | Transfusion 20070301 |
Quantification of viral inactivation by photochemical treatment with amotosalen and UV A light, using a novel polymerase chain reaction inhibition method with preamplification. | The Journal of infectious diseases 20061215 |
A randomized, controlled Phase III trial of therapeutic plasma exchange with fresh-frozen plasma (FFP) prepared with amotosalen and ultraviolet A light compared to untreated FFP in thrombotic thrombocytopenic purpura. | Transfusion 20061001 |
Photochemical treatment of plasma with amotosalen and long-wavelength ultraviolet light inactivates pathogens while retaining coagulation function. | Transfusion 20060701 |
Platelets photochemically treated with amotosalen HCl and ultraviolet A light correct prolonged bleeding times in patients with thrombocytopenia. | Transfusion 20060501 |
Pathogen inactivation of platelets with a photochemical treatment with amotosalen HCl and ultraviolet light: process used in the SPRINT trial. | Transfusion 20060401 |
Transfusion of 7-day-old amotosalen photochemically treated buffy-coat platelets to patients with thrombocytopenia: a pilot study. | Transfusion 20060301 |
In vitro evaluation of Haemonetics MCS+ apheresis platelet concentrates treated with photochemical pathogen inactivation following plasma volume reduction using the INTERCEPT Preparation Set. | Vox sanguinis 20060201 |
The role of photochemical treatment with amotosalen and UV-A light in the prevention of transfusion-transmitted cytomegalovirus infections. | Transfusion medicine reviews 20060101 |
Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light. | Transfusion 20060101 |
Effect of the psoralen-based photochemical pathogen inactivation on mitochondrial DNA in platelets. | Platelets 20051201 |
Clinical safety of platelets photochemically treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial. | Transfusion 20051201 |
Amotosalen interactions with platelet and plasma components: absence of neoantigen formation after photochemical treatment. | Transfusion 20051001 |
Therapeutic efficacy and safety of photochemically treated apheresis platelets processed with an optimized integrated set. | Transfusion 20050901 |
Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long-wavelength ultraviolet irradiation. | Transfusion 20050901 |
Polymerase chain reaction inhibition assay documenting the amotosalen-based photochemical pathogen inactivation process of platelet concentrates. | Transfusion 20050901 |
Fresh frozen plasma prepared with amotosalen HCl (S-59) photochemical pathogen inactivation: transfusion of patients with congenital coagulation factor deficiencies. | Transfusion 20050801 |
Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates. | Transfusion medicine (Oxford, England) 20050801 |
In vitro photochemical inactivation of cell-associated human T-cell leukemia virus Type I and II in human platelet concentrates and plasma by use of amotosalen. | Transfusion 20050701 |
Inactivation of viruses in platelet concentrates by photochemical treatment with amotosalen and long-wavelength ultraviolet light. | Transfusion 20050401 |
Protecting the blood supply from emerging pathogens: the role of pathogen inactivation. | Transfusion medicine reviews 20050401 |
Amotosalen-treated donor T cells have polyclonal antigen-specific long-term function without graft-versus-host disease after allogeneic bone marrow transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050301 |
Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia. | Annals of the New York Academy of Sciences 20050101 |
Recovery and life span of 111indium-radiolabeled platelets treated with pathogen inactivation with amotosalen HCl (S-59) and ultraviolet A light. | Transfusion 20041201 |
Photochemical treatment of platelet concentrates with amotosalen and long-wavelength ultraviolet light inactivates a broad spectrum of pathogenic bacteria. | Transfusion 20041001 |
Implementation of the INTERCEPT Blood System for Platelets into routine blood bank manufacturing procedures: evaluation of apheresis platelets. | Vox sanguinis 20040501 |
In vitro evaluation of pooled buffy coat platelets treated with photochemical pathogen inactivation using amotosalen. | Vox sanguinis 20040401 |
Functional characteristics of photochemically treated platelets. | Transfusion 20040301 |
Functional characteristics of buffy-coat PLTs photochemically treated with amotosalen-HCl for pathogen inactivation. | Transfusion 20040301 |
In vitro evaluation of COM.TEC apheresis platelet concentrates using a preparation set and pathogen inactivation over a storage period of five days. | Journal of clinical apheresis 20040101 |
Allogeneic T cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation. | Journal of immunology (Baltimore, Md. : 1950) 20031201 |
Preclinical safety profile of plasma prepared using the INTERCEPT Blood System. | Vox sanguinis 20031001 |
Safety of the blood supply: role of pathogen reduction. | Blood reviews 20030601 |
Transfusion of pooled buffy coat platelet components prepared with photochemical pathogen inactivation treatment: the euroSPRITE trial. | Blood 20030315 |
Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20030101 |
Multilineage engraftment with minimal graft-versus-host disease following in utero transplantation of S-59 psoralen/ultraviolet a light-treated, sensitized T cells and adult T cell-depleted bone marrow in fetal mice. | Journal of immunology (Baltimore, Md. : 1950) 20021201 |
Pharmacokinetic study of FFP photochemically treated with amotosalen (S-59) and UV light compared to FFP in healthy volunteers anticoagulated with warfarin. | Transfusion 20021001 |
[Blood donation]. | Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20020701 |
Preclinical safety of a nucleic acid-targeted Helinx compound: a clinical perspective. | Seminars in hematology 20011001 |
Pharmacokinetic and toxicology assessment of INTERCEPT (S-59 and UVA treated) platelets. | Human & experimental toxicology 20011001 |
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