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CAS No: 158876-82-5 Catalog No: AG001QYV MDL No:MFCD09039284
Title | Journal |
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Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2. | Journal of medicinal chemistry 20141126 |
Rupatadine 10 mg in the treatment of immediate mosquito-bite allergy. | Journal of the European Academy of Dermatology and Venereology : JEADV 20120701 |
Histamine and H1-antihistamines: celebrating a century of progress. | The Journal of allergy and clinical immunology 20111201 |
Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety. | Journal of drugs in dermatology : JDD 20111201 |
Fexofenadine-induced urticaria. | Annals of dermatology 20111201 |
Efficacy of second-generation antihistamines in patients with allergic rhinitis and comorbid asthma. | The Journal of asthma : official journal of the Association for the Care of Asthma 20111101 |
Fixed drug eruption against rupatadine fumarate. | The Journal of craniofacial surgery 20110901 |
Rupatadine for the treatment of allergic rhinitis and urticaria. | Expert review of clinical immunology 20110101 |
Rupatadine improves nasal symptoms, quality of life (ESPRINT-15) and severity in a subanalysis of a cohort of Spanish allergic rhinitis patients. | Journal of investigational allergology & clinical immunology 20110101 |
Morning and evening efficacy evaluation of rupatadine (10 and 20 mg), compared with cetirizine 10 mg in perennial allergic rhinitis: a randomized, double-blind, placebo-controlled trial. | Journal of asthma and allergy 20110101 |
In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin. | Journal of inflammation (London, England) 20110101 |
H1-antihistamine up-dosing in chronic spontaneous urticaria: patients' perspective of effectiveness and side effects--a retrospective survey study. | PloS one 20110101 |
Olopatadine hydrochloride and rupatadine fumarate in seasonal allergic rhinitis: A comparative study of efficacy and safety. | Journal of pharmacology & pharmacotherapeutics 20110101 |
Consensus statement on the management of urticaria. | Indian journal of dermatology 20110101 |
Effect of bilastine upon nasal obstruction. | Journal of investigational allergology & clinical immunology 20110101 |
Efficacy and tolerability of rupatadine at four times the recommended dose against histamine- and platelet-activating factor-induced flare responses and ex vivo platelet aggregation in healthy males. | The British journal of dermatology 20101201 |
Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety. | Archives of otolaryngology--head & neck surgery 20100801 |
Rupatadine does not potentiate the CNS depressant effects of lorazepam: randomized, double-blind, crossover, repeated dose, placebo-controlled study. | British journal of clinical pharmacology 20100601 |
No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines. | British journal of clinical pharmacology 20100401 |
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs. | Journal of medicinal chemistry 20100325 |
[Rupatadine, oral Rupatall]. | Journal de pharmacie de Belgique 20100301 |
Stereoselective synthesis of desloratadine derivatives as antagonist of histamine. | Bioorganic & medicinal chemistry 20100215 |
Rupatadine inhibits proinflammatory mediator secretion from human mast cells triggered by different stimuli. | International archives of allergy and immunology 20100101 |
Rupatadine and heart rhythm disturbances. | Clinical pharmacology and therapeutics 20100101 |
Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20100101 |
Rupatadine improves nasal symptoms, airflow and inflammation in patients with persistent allergic rhinitis: a pilot study. | Journal of biological regulators and homeostatic agents 20100101 |
Structurally diverse metal coordination compounds, bearing imidodiphosphinate and diphosphinoamine ligands, as potential inhibitors of the platelet activating factor. | Bioinorganic chemistry and applications 20100101 |
Paradoxical exacerbation of chronic urticaria by H1-antihistamines and montelukast. | European annals of allergy and clinical immunology 20091201 |
Rupatadine: pharmacological profile and its use in the treatment of allergic rhinitis. | Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India 20091201 |
Treatment of acquired cold urticaria with rupatadine. | Allergy 20090901 |
The use of a responder analysis to identify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg. | Journal of the European Academy of Dermatology and Venereology : JEADV 20090901 |
Pharmacological profile, efficacy and safety of rupatadine in allergic rhinitis. | Primary care respiratory journal : journal of the General Practice Airways Group 20090601 |
Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine. | Primary care respiratory journal : journal of the General Practice Airways Group 20090601 |
Heart rhythm disturbances associated with rupatadine: a case series from the Spanish and Portuguese pharmacovigilance systems. | Clinical pharmacology and therapeutics 20090501 |
Torsade de pointes associated with rupatadine. | Revista espanola de cardiologia 20090301 |
Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers. | Journal of pharmaceutical and biomedical analysis 20090220 |
Successful treatment of chronic drug-resistant urticaria with alprazolam. | The Journal of allergy and clinical immunology 20090201 |
Safety of rupatadine administered over a period of 1 year in the treatment of persistent allergic rhinitis: a multicentre, open-label study in Spain. | Drug safety 20090101 |
Futura study: evaluation of efficacy and safety of rupatadine fumarate in the treatment of persistent allergic rhinitis. | Brazilian journal of otorhinolaryngology 20090101 |
Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study. | Journal of investigational allergology & clinical immunology 20090101 |
Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. | Journal of asthma and allergy 20090101 |
Determination of rupatadine in pharmaceutical formulations by a validated stability-indicating MEKC method. | Journal of separation science 20080901 |
Herbex-kid Inhibits Immediate Hypersensitivity Reactions in Mice and Rats. | Evidence-based complementary and alternative medicine : eCAM 20080901 |
Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin at steady-state levels: a randomized, open-label, two-way, crossover, Phase I study. | Clinical therapeutics 20080901 |
High performance liquid chromatography-tandem mass spectrometric determination of rupatadine in human plasma and its pharmacokinetics. | Journal of pharmaceutical and biomedical analysis 20080805 |
A 12-week placebo-controlled study of rupatadine 10 mg once daily compared with cetirizine 10 mg once daily, in the treatment of persistent allergic rhinitis. | Allergy 20080701 |
[Torsades de pointes associated with rupatadine]. | Revista espanola de cardiologia 20080301 |
Antihistaminic effects of rupatadine and PKPD modelling. | European journal of drug metabolism and pharmacokinetics 20080101 |
Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers. | Human psychopharmacology 20070701 |
Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicentre study. | Allergy 20070501 |
Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study. | Clinical therapeutics 20070501 |
[Protective effect of rupatadine against oleic acid-induced acute lung injury in rabbits]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070301 |
Once-daily rupatadine improves the symptoms of chronic idiopathic urticaria: a randomised, double-blind, placebo-controlled study. | European journal of dermatology : EJD 20070101 |
Characterization of the de novo biosynthetic enzyme of platelet activating factor, DDT-insensitive cholinephosphotransferase, of human mesangial cells. | Mediators of inflammation 20070101 |
[Antihistamines in allergic rhinitis]. | Otolaryngologia polska = The Polish otolaryngology 20070101 |
The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes. | European journal of pharmacology 20061228 |
New antihistamines: a critical view. | Jornal de pediatria 20061101 |
Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers. | Human psychopharmacology 20060101 |
Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060101 |
Rupatadine 10 mg and cetirizine 10 mg in seasonal allergic rhinitis: a randomised, double-blind parallel study. | Journal of investigational allergology & clinical immunology 20050101 |
Rupatadine 10 mg and ebastine 10 mg in seasonal allergic rhinitis: a comparison study. | Allergy 20040701 |
Role of histamine and platelet-activating factor in allergic rhinitis. | Journal of physiology and biochemistry 20040601 |
A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis. | Journal of investigational allergology & clinical immunology 20040101 |
Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers. | Neuropsychobiology 20040101 |
Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis. | Drugs of today (Barcelona, Spain : 1998) 20030601 |
Antihistamines in late-phase clinical development for allergic disease. | Expert opinion on investigational drugs 20020201 |
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