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15826-37-6

15826-37-6 | 4H-1-Benzopyran-2-carboxylicacid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, sodium salt (1:2)

CAS No: 15826-37-6 Catalog No: AG003UC5 MDL No:MFCD12197279

Product Description

Catalog Number:
AG003UC5
Chemical Name:
4H-1-Benzopyran-2-carboxylicacid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, sodium salt (1:2)
CAS Number:
15826-37-6
Molecular Formula:
C23H14Na2O11
Molecular Weight:
512.3302
MDL Number:
MFCD12197279
IUPAC Name:
disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate
InChI:
InChI=1S/C23H16O11.2Na/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;/q;2*+1/p-2
InChI Key:
VLARUOGDXDTHEH-UHFFFAOYSA-L
SMILES:
OC(COc1cccc2c1c(=O)cc(o2)C(=O)[O-])COc1cccc2c1c(=O)cc(o2)C(=O)[O-].[Na+].[Na+]
EC Number:
239-926-7
UNII:
Q2WXR1I0PK
RTECS Number:
DJ2380000

Properties

Complexity:
824  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
512.033g/mol
Formal Charge:
0
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
512.334g/mol
Monoisotopic Mass:
512.033g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
172A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
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Molecularly imprinted polymers for histamine recognition in aqueous environment. Amino acids 20121101
Inhibiting tryptase after ischemia limits small intestinal ischemia-reperfusion injury through protease-activated receptor 2 in rats. The journal of trauma and acute care surgery 20121101
Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice. Laboratory investigation; a journal of technical methods and pathology 20121001
Mast cells activation contribute to small intestinal ischemia reperfusion induced acute lung injury in rats. Injury 20120801
Pseudobronchiectasis after pertussis and mycoplasma infection. American journal of respiratory and critical care medicine 20120801
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Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. Journal of immunology (Baltimore, Md. : 1950) 20061115
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Protective effects of nedocromil sodium and sodium cromoglycate on gastroduodenal ulcers: a comparative study in rats. Inflammopharmacology 20060801
Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents. The American journal of pathology 20060701
Lyotropic liquid crystal as a real-time detector of microbial immune complexes. Letters in applied microbiology 20060701
Assessing the impact of asthma guideline implementation. Chest 20060701
The interaction and compatibility between a soft contact lens and an ophthalmic drug. Eye & contact lens 20060701
Cerebral mast cells regulate early ischemic brain swelling and neutrophil accumulation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060501
Exhaled carbon monoxide levels in school-age children with episodic asthma. Pediatric pulmonology 20060501
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The effect of cromoglycate on time-dependent histamine and serotonin concentrations in stored blood products. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20060401
Nociceptin-induced histamine release in the brain: comparison with compound 48/80- and substance P-induced amine secretions. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401
The inhibitory effect of disodium cromoglycate on the growth of Chlamydophila (Chlamydia) pneumoniae in vitro. Biological & pharmaceutical bulletin 20060401
Expression of urocortin in rat lung and its effect on pulmonary vascular permeability. The Journal of endocrinology 20060401
Cromolyn sodium: a potential therapy for uremic pruritus? Hemodialysis international. International Symposium on Home Hemodialysis 20060401
Inhibition of mast cell degranulation-induced drop of blood pressure with clemastine, cromolyn and compound 48/80 pretreatment. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401
Effects of nebulized sodium cromoglycate on adult patients with severe refractory asthma. Respiratory medicine 20060301
Mucosal eosinophilia and response to H1/H2 antagonist and cromolyn therapy in pediatric dyspepsia. Clinical pediatrics 20060301
Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin. The Journal of pharmacy and pharmacology 20060301
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Managing asthma in expectant mothers. Treatments in respiratory medicine 20060101
Oral beta2-agonist use by preschool children with asthma in East and Central Harlem, New York. The Journal of asthma : official journal of the Association for the Care of Asthma 20060101
Mononuclear cell membranes: stabilization by reproterol and cromoglycate, destabilization by fenoterol and salbutamol. Arzneimittel-Forschung 20060101
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Forskolin versus sodium cromoglycate for prevention of asthma attacks: a single-blinded clinical trial. The Journal of international medical research 20060101
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A cross-sectional study of medication-related factors and caries experience in asthmatic children. Pediatric dentistry 20060101
Nebulized drug admixtures: effect on aerosol characteristics and albuterol output. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101
Interaction of cromolyn sodium with human serum albumin: a fluorescence quenching study. Bioorganic & medicinal chemistry 20051215
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Eosinophilic esophagitis: a 10-year experience in 381 children. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20051201
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Involvement of mast cells in the development of fibrosis in rats with postmyocarditis dilated cardiomyopathy. Biological & pharmaceutical bulletin 20051101
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Effect of amino acids on the dispersion of disodium cromoglycate powders. Journal of pharmaceutical sciences 20051001
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Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats. Peptides 20050901
Efficacy, cost-effectiveness, and tolerability of mometasone furoate, levocabastine, and disodium cromoglycate nasal sprays in the treatment of seasonal allergic rhinitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901
Mast cell involvement in the adenosine mediated airway hyper-reactivity in a murine model of ovalbumin-induced lung inflammation. British journal of pharmacology 20050801
The effect of water to ethanol feed ratio on physical properties and aerosolization behavior of spray dried cromolyn sodium particles. Journal of pharmaceutical sciences 20050501
The challenge of mild persistent asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050501
[Hyper-IgE syndrome]. Nihon rinsho. Japanese journal of clinical medicine 20050501
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The discovery of cromolyn sodium and its effect on research and practice in allergy and immunology. The Journal of allergy and clinical immunology 20050401
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Predicting the clinical course of suspected acute viral upper respiratory tract infection in children. Family practice 20050201
Asthma controller therapy during pregnancy. American journal of obstetrics and gynecology 20050201
Efficacy and acceptability of a new topical skin lotion of sodium cromoglicate (Altoderm) in atopic dermatitis in children aged 2-12 years: a double-blind, randomized, placebo-controlled trial. The British journal of dermatology 20050201
NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. The Journal of allergy and clinical immunology 20050101
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Lung deposition after electronically breath-controlled inhalation and manually triggered conventional inhalation in cystic fibrosis patients. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20050101
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Prevention of adhesions by sodium chromoglycate, dexamethasone, saline and aprotinin after pelvic surgery. ANZ journal of surgery 20041201
Oral absorption enhancement of cromolyn sodium through noncovalent complexation. Pharmaceutical research 20041201
The effect of vehicle on physical properties and aerosolisation behaviour of disodium cromoglycate microparticles spray dried alone or with L-leucine. International journal of pharmaceutics 20041105
Pharmacologic approaches to daytime and nighttime symptoms of allergic rhinitis. The Journal of allergy and clinical immunology 20041101
Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women. American journal of obstetrics and gynecology 20041101
The effect of montelukast versus usual care on health care resource utilization in children aged 2 to 5 years with asthma. Clinical therapeutics 20041101
Induction of premature labor and delivery by allergic reaction and prevention by histamine H1 receptor antagonist. American journal of obstetrics and gynecology 20041001
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Induced sputum in children with newly diagnosed mild asthma: the effect of 6 months of treatment with budesonide or disodium cromoglycate. Allergy 20040801
Cough and angioedema from angiotensin-converting enzyme inhibitors: new insights into mechanisms and management. Current opinion in allergy and clinical immunology 20040801
Prevention of bronchoconstriction in sensitized guinea pigs: efficacy of common prophylactic drugs. Respiratory physiology & neurobiology 20040720
Tolerance induction to rofecoxib in a patient with Bartter's syndrome. Allergy 20040701
Are inhaled corticosteroids safe and effective in infants with asthma-like symptoms? Pediatrics 20040701
In vitro and in vivo inhibitory effects of disodium cromoglycate on influenza virus infection. Biological & pharmaceutical bulletin 20040601
Asthma and other wheezing disorders in infants and children. Clinical evidence 20040601
Disodium cromoglycate stabilizes mast cell degranulation while reducing the number of hemoglobin-induced microvascular leaks in rat mesentery. American journal of physiology. Heart and circulatory physiology 20040501
Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats. Neuropharmacology 20040501
Self-association of cromolyn sodium in aqueous solution characterized by nuclear magnetic resonance spectroscopy. Journal of pharmaceutical sciences 20040501
Mast cells and reactive oxygen species in citric acid-induced airway constriction. Journal of applied physiology (Bethesda, Md. : 1985) 20040501
Effect of disodium cromoglycate on mast cell-mediated immediate-type allergic reactions. Life sciences 20040423
[Pediatric bronchial asthma. How reliable are the guidelines?]. MMW Fortschritte der Medizin 20040422
LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam. Phytochemistry 20040401
Disodium cromoglycate suppresses the induction of cysteinyl leukotriene synthesis during granulocytic differentiation in HL-60 cells. Respiratory medicine 20040301
Mast cells degranulation affects angiogenesis in the rat uterine cervix during pregnancy. Reproduction (Cambridge, England) 20040301
Histamine and fluoxetine: common playground in the rat conjunctiva? Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301
Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing. Pediatrics 20040201
A method for determining whether hypotension caused by novel compounds in preclinical development results from histamine release. Journal of pharmacological and toxicological methods 20040101
A simple pharmacokinetic method to evaluate the pulmonary dose in clinical practice--analyses of inhaled sodium cromoglycate. Respiratory medicine 20040101
Treatment of allergic rhinitis during pregnancy. American journal of rhinology 20040101
Inhaled cromones for prolonged non-specific cough in children. The Cochrane database of systematic reviews 20040101
Does wearing a noseclip during inhalation improve lung deposition? Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20040101
Acute asthma attack caused by ophthalmic application of antiallergic agents. Japanese journal of ophthalmology 20040101
Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? Journal of toxicology. Clinical toxicology 20040101
Single-dose agents in the prevention of exercise-induced asthma: a descriptive review. Treatments in respiratory medicine 20040101
[Lung functioning changes of asthmatic adults in treatment with cromolyn sodium and beclomethasone]. Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101
Activation of mast cells by systemic hypoxia, but not by local hypoxia, mediates increased leukocyte-endothelial adherence in cremaster venules. Journal of applied physiology (Bethesda, Md. : 1985) 20031201
Clinical course of acute infection of the upper respiratory tract in children: cohort study. BMJ (Clinical research ed.) 20031108
Disodium cromoglycate prevents ileum hyperreactivity to histamine in Toxocara canis-infected guinea pigs. Pharmacological research 20031101
No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis. Pediatric pulmonology 20031101
Hyaluronidase inhibitors (sodium cromoglycate and sodium auro-thiomalate) reduce the local tissue damage and prolong the survival time of mice injected with Naja kaouthia and Calloselasma rhodostoma venoms. Toxicon : official journal of the International Society on Toxinology 20031101
Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer. International journal of cancer 20031020
Norepinephrine-induced cardiac hypertrophy and fibrosis are not due to mast cell degranulation. Molecular and cellular biochemistry 20031001
Cost-effective pharmacotherapy for inhalant allergic rhinitis. Otolaryngologic clinics of North America 20031001
Salmeterol versus sodium cromoglycate for the protection of exercise induced asthma in children--a randomised cross-over study. European journal of medical research 20030929
Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox. The Biochemical journal 20030901
Effects of budesonide inhalation suspension compared with cromolyn sodium nebulizer solution on health status and caregiver quality of life in childhood asthma. Pediatrics 20030901
Tricin from a malagasy connaraceous plant with potent antihistaminic activity. Journal of natural products 20030901
Oral disodium cromoglycate and ketotifen for a patient with eosinophilic gastroenteritis, food allergy and protein-losing enteropathy. Asian Pacific journal of allergy and immunology 20030901
No effect of cromoglycate treatment in hospitalized infants with respiratory syncytial virus bronchiolitis. Pediatric pulmonology 20030801
The role of the mast cell in asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030801
Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice. Cardiovascular research 20030701
Salmeterol resolves airway obstruction but does not possess anti-eosinophil efficacy in newly diagnosed asthma: a randomized, double-blind, parallel group biopsy study comparing the effects of salmeterol, fluticasone propionate, and disodium cromoglycate. The Journal of allergy and clinical immunology 20030701
General strategy for the management of bronchial asthma in pregnancy. Respiratory medicine 20030701
Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products. American journal of obstetrics and gynecology 20030601
Antiallergic activity of ginseng and its ginsenosides. Planta medica 20030601
Asthma and other wheezing disorders of childhood. Clinical evidence 20030601
Development and validation of a sensitive liquid chromatographic-tandem mass spectrometric method for the determination of cromolyn sodium in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Anti-inflammatory treatment for recurrent wheezing in the first five years of life. Pediatric pulmonology 20030401
Effect of protease-activated receptors on guinea-pig ileum contraction in vitro. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401
A combined analysis of two studies assessing the ocular comfort of antiallergy ophthalmic agents. Clinical therapeutics 20030401
Treatment compliance, passive smoking, and asthma control: a three year cohort study. Archives of disease in childhood 20030301
Adenosine monophosphate bronchial provocation and the actions of asthma therapy. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030301
Salbutamol, beclomethasone or sodium chromoglycate suppress coughing induced by iv fentanyl. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030301
In-situ-micronization of disodium cromoglycate for pulmonary delivery. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030301
The role of aspirin in vernal keratoconjunctivitis. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20030301
The anti-allergic effects of a cromolyn sodium-chlorpheniramine combination compared to ketotifen in the conjunctival allergen challenge model. European journal of ophthalmology 20030301
A systematic review of alternative therapies in the irritable bowel syndrome. Archives of internal medicine 20030210
Oral desensitizing treatment in food allergy: clinical and immunological results. Alimentary pharmacology & therapeutics 20030201
Nicorandil: albuterol-like or cromolyn-like? Critical care medicine 20030201
Gastric hypersecretion associated to iodoacetamide-induced mild gastritis in mice. Naunyn-Schmiedeberg's archives of pharmacology 20030201
Asthma prevalence and drug prescription in asthmatic children. European annals of allergy and clinical immunology 20030201
Preparation and evaluation of a liposomal formulation of sodium cromoglicate. International journal of pharmaceutics 20030130
Mast cells mediate the microvascular inflammatory response to systemic hypoxia. Journal of applied physiology (Bethesda, Md. : 1985) 20030101
Pycnogenol inhibits the release of histamine from mast cells. Phytotherapy research : PTR 20030101
Long-term management of asthma. Indian journal of pediatrics 20030101
Lung deposition in cystic fibrosis patients using an ultrasonic or a jet nebulizer. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20030101
Comparison of the efficacy and tolerability of topically administered azelastine, sodium cromoglycate and placebo in the treatment of seasonal allergic conjunctivitis and rhino-conjunctivitis. Current medical research and opinion 20030101
Inhaled sodium cromoglycate for asthma in children. The Cochrane database of systematic reviews 20030101
Evaluation of parental preference for the treatment of asthmatic children aged 6 to 11 years with oral montelukast or inhaled cromolyn: a randomized, open-label, crossover study. The Journal of asthma : official journal of the Association for the Care of Asthma 20030101
[Study of biopharmaceutic characteristics of cromoglycate eye drops]. Medicina (Kaunas, Lithuania) 20030101
[Longitudinal study of children with bronchopulmonary dysplasia treated with disodium cromoglycate]. Medycyna wieku rozwojowego 20030101
Inhalation and deposition of nebulized sodium cromoglycate in two different particle size distributions in children with asthma. Pediatric pulmonology 20021101
Long-term management of asthma in children: effectiveness of inhaled corticosteroids compared to other medications. The Journal of allergy and clinical immunology 20021101
Sodium cromoglycate and doxantrazole are oxygen radical scavengers. The European respiratory journal 20021001
A comparison of the efficacy and tolerability of olopatadine hydrochloride 0.1% ophthalmic solution and cromolyn sodium 2% ophthalmic solution in seasonal allergic conjunctivitis. Clinical therapeutics 20021001
The role of sodium cromolyn in treatment of paraquat-induced pulmonary fibrosis in rat. Pharmacological research 20020901
[Enhancing effects of ion-pair complexes on skin permeation of cromolyn in vitro]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020901
Mast cells as a target of rheumatoid arthritis treatment. Japanese journal of pharmacology 20020901
Inhaled sodium cromoglycate in children with asthma. Thorax 20020801
In vitro deposition of the respirable fraction of dry powder inhalations determined by laser diffractometry and inertial impaction. Die Pharmazie 20020801
Water dynamics in channel hydrates investigated using H/D exchange. International journal of pharmaceutics 20020725
Fluticasone for the treatment of symptomatic bronchial asthma in children treated with sodium cromogylate--a prospective, randomised trial. European journal of medical research 20020628
[Exercise-induced asthma. Not a reason to be benched]. MMW Fortschritte der Medizin 20020627
Management of suspected acute viral upper respiratory tract infection in children with intranasal sodium cromoglicate: a randomised controlled trial. Lancet (London, England) 20020622
Generalized bullae in an infant. Archives of dermatology 20020601
Balancing safety and efficacy in the treatment of pediatric asthma. The Journal of allergy and clinical immunology 20020601
(S)nifty treatment for pollen allergies. Health news (Waltham, Mass.) 20020601
One-year trial on safety and normal linear growth with flunisolide HFA in children with asthma. Clinical pediatrics 20020601
Allergic rhinitis remains an important disease. The Journal of the American Osteopathic Association 20020601
Improved strategies and new treatment options for allergic rhinitis. The Journal of the American Osteopathic Association 20020601
Efficacy and patient satisfaction with cromolyn sodium nasal solution in the treatment of seasonal allergic rhinitis: a placebo-controlled study. Clinical therapeutics 20020601
The combination of nebulized sodium cromoglycate and salbutamol in the treatment of moderate-to-severe asthma in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020601
Airway hyperresponsiveness to adenosine induced by lipopolysaccharide in Brown Norway rats. British journal of pharmacology 20020501
Nebulized budesonide inhalation suspension compared with cromolyn sodium nebulizer solution for asthma in young children: results of a randomized outcomes trial. Pediatrics 20020501
Relative lung and systemic bioavailability of sodium cromoglycate inhaled products using urinary drug excretion post inhalation. Biopharmaceutics & drug disposition 20020501
Floating a metered-dose inhaler is not an accurate measure of remaining medicine. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501
Ischaemic preconditioning and mast cell histamine release: microdialysis of isolated rat hearts. Pharmacological research 20020501
Effect of interventions during acute respiratory syncytial virus bronchiolitis on subsequent long term respiratory morbidity. The Pediatric infectious disease journal 20020501
Management of allergic and nonallergic rhinitis. Evidence report/technology assessment (Summary) 20020501
Perinatal immunomodulation. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20020501
Interaction of S100 proteins with the antiallergic drugs, olopatadine, amlexanox, and cromolyn: identification of putative drug binding sites on S100A1 protein. Biochemical and biophysical research communications 20020412
Use of intranasal cromolyn sodium for allergic rhinitis. Mayo Clinic proceedings 20020401
Inhaled sodium cromoglycate in children with asthma. Thorax 20020301
Medical management of Cronkhite-Canada syndrome. Southern medical journal 20020201
Efficacy and safety of inhaled steroid and cromone treatment in school-age children: a randomized pragmatic pilot study. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20020201
The effect of cosolvents on the formulation of nanoparticles from low-molecular-weight poly(l)lactide. AAPS PharmSciTech 20020201
Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats. Life sciences 20020118
From khellin to sodium cromoglycate--a tribute to the work of Dr. R. E. C. Altounyan (1922-1987). Die Pharmazie 20020101
The effect of disodium cromoglycate, budesonide, and cyclosporin A on interleukin-4, interleukin-5, and interleukin-13 secretions in Der p I-stimulated T cells from house dust mite-sensitive atopic and nonatopic individuals. Allergy and asthma proceedings 20020101
Topical treatment of pyoderma gangraenosum. Dermatology (Basel, Switzerland) 20020101
Single dose of ketotifen fumarate .025% vs 2 weeks of cromolyn sodium 4% for allergic conjunctivitis. Advances in therapy 20020101
Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion. American journal of respiratory medicine : drugs, devices, and other interventions 20020101
Determination of sodium cromoglycate in human plasma by liquid chromatography-mass spectrometry in the turbo ion spray mode. Journal of chromatography. B, Biomedical sciences and applications 20011225
Reasons for and costs of hospitalization for pediatric asthma: a prospective 1-year follow-up in a population-based setting. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20011201
[Inhalation therapy]. Annales de medecine interne 20011201
[Effects of roxithromycin on proliferation and activation of mast cells]. The Japanese journal of antibiotics 20011201
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Therapy choices beyond antihistamines. Vasomotor rhinitis. Advance for nurse practitioners 20011101
[Inhaled corticosteroid therapy in childhood asthma]. Nihon rinsho. Japanese journal of clinical medicine 20011001
Effect of specific immunotherapy versus loratadine on serum adhesion molecules. Allergie et immunologie 20011001
Inhaled sodium cromoglycate in the management of asthma: should it be consigned to history? Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901
Sodium cromoglycate attenuates pulmonary inflammation without influencing bronchial responsiveness in healthy subjects exposed to organic dust. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901
[Sodium cromoglycate in the treatment of food hypersensitivity in children under 3 years of age]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010901
Antiallergic/antiasthmatic effect of novel antiallergic hexapeptide-95/220 in various experimental models. Indian journal of experimental biology 20010901
Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice. The Journal of pharmacology and experimental therapeutics 20010801
Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatric research 20010801
Asthma symptoms, morbidity, and antiinflammatory use in inner-city children. Pediatrics 20010801
Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010801
[Exercise-induced asthma. The spray belongs in the 'athletic shoe']. MMW Fortschritte der Medizin 20010719
Sodium cromoglycate in the management of chronic or recurrent enterocolitis in patients with Hirschsprung's disease. Journal of pediatric surgery 20010701
A novel pharmacologic action of glucocorticosteroids on leukotriene C4 catabolism. The Journal of allergy and clinical immunology 20010701
Inhaled sodium cromoglycate. Thorax 20010701
The necessity for dual food intake to provoke food-dependent exercise-induced anaphylaxis (FEIAn): a case report of FEIAn with simultaneous intake of wheat and umeboshi. The Journal of allergy and clinical immunology 20010601
Time to consign cromoglycate to history? Thorax 20010601
Asthma in the hospitalized obstetrical patient. Clinical reviews in allergy & immunology 20010601
The efficacy and safety of asthma medications during pregnancy. Seminars in perinatology 20010601
Antihistamines and serum adhesion molecule levels. Allergie et immunologie 20010601
Comparison of the cost-effectiveness of budesonide and sodium cromoglycate in the management of childhood asthma in everyday clinical practice. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010501
[Color reactions for identification of sodium cromoglycate]. Die Pharmazie 20010501
Disodium cromoglycate inhibits production of immunoglobulin E. Immunopharmacology and immunotoxicology 20010501
[Preventive monotherapy with montelukast versus DNCG in children with mild asthma. Results of and exploratory pilot study]. Pneumologie (Stuttgart, Germany) 20010501
Management of pyoderma gangrenosum. Hospital practice (1995) 20010415
Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats. British journal of pharmacology 20010401
Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve. British journal of pharmacology 20010401
Sodium cromoglycate in childhood asthma. Thorax 20010401
Impact of inhaled antiinflammatory therapy on hospitalization and emergency department visits for children with asthma. Pediatrics 20010401
Pyrazolopyrimidines: synthesis, effect on histamine release from rat peritoneal mast cells and cytotoxic activity. European journal of medicinal chemistry 20010401
Comparative functional characterization of mouse bone marrow-derived mast cells and peritoneal mast cells in response to non-immunological stimuli. Indian journal of experimental biology 20010401
Tear tryptase in vernal keratoconjunctivitis. Archives of ophthalmology (Chicago, Ill. : 1960) 20010301
Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats. Japanese journal of pharmacology 20010301
[Anti-allergy therapy in children]. Allergie et immunologie 20010301
Cromolyn cream for recalcitrant idiopathic vulvar vestibulitis: results of a placebo controlled study. Sexually transmitted infections 20010201
[Antioxidant effects of mast cell inhibitors in a human conjunctival cell line]. Journal francais d'ophtalmologie 20010201
Acute stress increases permeability of the blood-brain-barrier through activation of brain mast cells. Brain research 20010105
The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception. Neuroscience 20010101
Role of mast cells in zymosan-induced peritoneal inflammation in Balb/c and mast cell-deficient WBB6F1 mice. Journal of leukocyte biology 20010101
Ultrasonic nebulization system for respiratory drug delivery. Pharmaceutical development and technology 20010101
Relative lung bioavailability of generic sodium cromoglycate inhalers used with and without a spacer device. Pulmonary pharmacology & therapeutics 20010101
Nedocromil sodium versus sodium cromoglycate in treatment of exercise-induced bronchoconstriction: a systematic review. The European respiratory journal 20010101
Do rural and urban children have comparable asthma care utilization? The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association 20010101
Cromolyn sodium for the prevention of chronic lung disease in preterm infants. The Cochrane database of systematic reviews 20010101
[Changes in biochemical inflammation markers in evaluation of the effectiveness of basic chemotherapy in bronchial asthma]. Terapevticheskii arkhiv 20010101
[A sniffing child]. Duodecim; laaketieteellinen aikakauskirja 20010101
Mechanisms and comparison of anti-allergic efficacy of topical lodoxamide and cromolyn sodium treatment in vernal keratoconjunctivitis. Ophthalmology 20000701
Evaluation of a clinical algorithm involving serum eosinophil cationic protein for guiding the anti-inflammatory treatment of bronchial asthma in childhood. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20000501
Montelukast, a leukotriene receptor antagonist, reduces the concentration of leukotrienes in the respiratory tract of children with persistent asthma. The Journal of allergy and clinical immunology 19991201
Substance P may attenuate gastric hyperemia by a mast cell-dependent mechanism in the damaged gastric mucosa. The American journal of physiology 19991101
Disodium cromoglycate does not prevent terbutaline-induced desensitization of beta 2-adrenoceptor-mediated cardiovascular in vivo functions in human volunteers. Journal of cardiovascular pharmacology 19990501
Inhibition of anaphylaxis by sulfasalazine in rats. Pharmacology 19980501
Contribution of mast cell mediators to alterations in macrophage function after malathion administration. Fundamental and applied toxicology : official journal of the Society of Toxicology 19960901
Lodoxamide in vernal keratoconjunctivitis. The Annals of pharmacotherapy 19960501
Inhibition of volume-activated chloride currents in endothelial cells by chromones. British journal of pharmacology 19950801
Cardiotoxicity of doxorubicin: effects of drugs inhibiting the release of vasoactive substances. Pharmacology & toxicology 19940801
Methotrexate treatment of severe asthma in children. Pediatrics 19920401
The relationship between adrenal vascular events and steroid secretion: the role of mast cells and endothelin. The Journal of steroid biochemistry and molecular biology 19910101
Amelioration of 4'-epidoxorubicin-induced cardiotoxicity by sodium cromoglycate. European journal of cancer & clinical oncology 19890201
Assay of specific IgE antibodies to disodium cromoglycate in serum from a patient with an immediate hypersensitivity reaction. The Journal of allergy and clinical immunology 19880401
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