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Home > Other Building Blocks > 156719-41-4
156719-41-4 | L-Ornithine, N5-[imino(methylthio)methyl]-
CAS No: 156719-41-4 Catalog No: AG001OX4 MDL No:
Product Description
Catalog Number:
AG001OX4
Chemical Name:
L-Ornithine, N5-[imino(methylthio)methyl]-
CAS Number:
156719-41-4
Molecular Formula:
C7H15N3O2S
Molecular Weight:
205.2779
IUPAC Name:
(2S)-2-amino-5-[[amino(methylsulfanyl)methylidene]amino]pentanoic acid
InChI:
InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1
InChI Key:
NGVMVBQRKZPFLB-YFKPBYRVSA-N
SMILES:
CSC(=N)NCCC[C@@H](C(=O)O)N
UNII:
M790X706JV
Properties
Complexity:
196
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
205.088g/mol
Formal Charge:
0
Heavy Atom Count:
13
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
205.276g/mol
Monoisotopic Mass:
205.088g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
127A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.7
Literature
| Title | Journal |
|---|---|
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| Chemical modulators of the innate immune response alter gypsy moth larval susceptibility to Bacillus thuringiensis. | BMC microbiology 20100101 |
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| Neuronal nitric oxide synthase and human vascular regulation. | Trends in cardiovascular medicine 20091101 |
| Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine. | American journal of physiology. Regulatory, integrative and comparative physiology 20091001 |
| Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure. | The journal of physiological sciences : JPS 20090701 |
| Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo. | Circulation 20090526 |
| A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice. | The journal of pain : official journal of the American Pain Society 20090201 |
| Exercise training improves peripheral chemoreflex function in heart failure rabbits. | Journal of applied physiology (Bethesda, Md. : 1985) 20080901 |
| Altered mesenteric venous capacitance and volume pooling in cirrhotic rats are mediated by nitric oxide. | American journal of physiology. Gastrointestinal and liver physiology 20080801 |
| Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP. | The European journal of neuroscience 20080801 |
| Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase. | Anesthesiology 20080701 |
| Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban. | American journal of physiology. Cell physiology 20080601 |
| Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. II. Effects of renal mass reduction. | American journal of physiology. Regulatory, integrative and comparative physiology 20080601 |
| Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo. | Circulation 20080415 |
| Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20080401 |
| Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress. | Anesthesiology 20080201 |
| Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. | American journal of physiology. Renal physiology 20080101 |
| Non-invasive measurements of exhaled NO and CO associated with methacholine responses in mice. | Respiratory research 20080101 |
| Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia. | The Journal of biological chemistry 20071130 |
| A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. | Journal of neurochemistry 20071101 |
| Brain stem NO modulates ventilatory acclimatization to hypoxia in mice. | Journal of applied physiology (Bethesda, Md. : 1985) 20071101 |
| Does nitric oxide act in the ventromedial preoptic area to mediate oestrogen negative feedback in the seasonally anoestrous ewe? | Reproduction (Cambridge, England) 20070701 |
| Renal tissue NO and intrarenal haemodynamics during experimental variations of NO content in anaesthetised rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070301 |
| Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption. | Acta physiologica Hungarica 20070301 |
| nNOS is involved in behavioral thermoregulation of newborn rats during hypoxia. | Physiology & behavior 20061230 |
| PIP3EA and PD-168077, two selective dopamine D4 receptor agonists, induce penile erection in male rats: site and mechanism of action in the brain. | The European journal of neuroscience 20061001 |
| Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways. | American journal of physiology. Renal physiology 20060601 |
| Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa. | Biochemistry 20060502 |
| Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. | American journal of physiology. Regulatory, integrative and comparative physiology 20060401 |
| The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: involvement of paraventricular glutamic acid and nitric oxide. | Neuropharmacology 20060201 |
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| Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat. | The Journal of physiology 20051215 |
| Nitric oxide synthase inhibition affects sarcoplasmic reticulum Ca2+ release in skeletal muscle fibres from mouse. | The Journal of physiology 20050915 |
| A continuous spectrophotometric assay for dimethylarginine dimethylaminohydrolase. | Analytical biochemistry 20050815 |
| Gene transfer of neuronal nitric oxide synthase to carotid body reverses enhanced chemoreceptor function in heart failure rabbits. | Circulation research 20050805 |
| Hypothalamic release of nitric oxide and interaction with amino acid neurotransmitters in chronically uraemic rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801 |
| Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II. | Kidney international 20050801 |
| Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-Stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland. | Investigative ophthalmology & visual science 20050801 |
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| Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis. | Biochemistry 20050510 |
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| Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina. | The Journal of comparative neurology 20050314 |
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| Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain. | The Journal of pharmacology and experimental therapeutics 20050201 |
| Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases. | Acta physiologica Scandinavica 20050101 |
| Up-regulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide synthase-deficient mice. | Journal of cardiovascular pharmacology 20041001 |
| A novel role for cholecystokinin: regulation of mesenteric vascular resistance. | Regulatory peptides 20040915 |
| Effects of long-term inhibition of neuronal nitric oxide synthase (NOS1) in uninephrectomized diabetic rats. | Nitric oxide : biology and chemistry 20040901 |
| Highly selective iNOS inhibition and sphincter of Oddi motility in the Australian possum. | Acta physiologica Scandinavica 20040701 |
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| Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats. | British journal of pharmacology 20030701 |
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| GABA(A) and GABA(C) receptor antagonists increase retinal cyclic GMP levels through nitric oxide synthase. | Visual neuroscience 20030101 |
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| A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain. | British journal of pharmacology 20011201 |
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