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15646-46-5

15646-46-5 | 5(4H)-Oxazolone, 4-(ethoxymethylene)-2-phenyl-

CAS No: 15646-46-5 Catalog No: AG001OQS MDL No:MFCD03225480

Product Description

Catalog Number:
AG001OQS
Chemical Name:
5(4H)-Oxazolone, 4-(ethoxymethylene)-2-phenyl-
CAS Number:
15646-46-5
Molecular Formula:
C12H11NO3
Molecular Weight:
217.2206
MDL Number:
MFCD03225480
IUPAC Name:
(4E)-4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5-one
InChI:
InChI=1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8+
InChI Key:
SJHPCNCNNSSLPL-CSKARUKUSA-N
SMILES:
CCOC=C1N=C(OC1=O)c1ccccc1
EC Number:
239-713-9
UNII:
40RAK33386

Properties

Complexity:
327  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
217.074g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
217.224g/mol
Monoisotopic Mass:
217.074g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
47.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.1  

Literature

Title Journal
Gene expression profiles in auricle skin as a possible additional endpoint for determination of sensitizers: A multi-endpoint evaluation of the local lymph node assay. Toxicology letters 20171005
In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly. Proceedings of the National Academy of Sciences of the United States of America 20150303
Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis. Toxicology in vitro : an international journal published in association with BIBRA 20131201
Targeting sphingosine kinase 1 (SphK1) and apoptosis by colon-specific delivery formula of resveratrol in treatment of experimental ulcerative colitis in rats. European journal of pharmacology 20131015
Attempts toward the synthesis of the peptaibol antiamoebin by using the 'azirine/oxazolone method'. Chemistry & biodiversity 20130501
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization. The Journal of pharmacology and experimental therapeutics 20130301
Deficiency of annexin A1 in CD4+ T cells exacerbates T cell-dependent inflammation. Journal of immunology (Baltimore, Md. : 1950) 20130201
Contact hypersensitivity to oxazolone provokes vulvar mechanical hyperalgesia in mice. PloS one 20130101
On the mechanism of the Dakin-West reaction. Organic & biomolecular chemistry 20121207
A chronic and latent lymphatic insufficiency follows recovery from acute lymphedema in the rat foreleg. American journal of physiology. Heart and circulatory physiology 20121101
Gastrointestinal microbiota and local inflammation during oxazolone-induced dermatitis in BALB/cA mice. Comparative medicine 20121001
A quantitative approach to assess the potency of skin sensitizers in the elicitation phase. Toxicology 20120904
Spectral characteristics of 4-(p-N,N-dimethyl-aminophenylmethylene)-2-phenyl-5-oxazolone (DPO) in different media. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901
A novel ring oxidation of 4- or 5-substituted 2H-oxazole to corresponding 2-oxazolone catalyzed by cytosolic aldehyde oxidase. Drug metabolism and disposition: the biological fate of chemicals 20120901
Oral administration of glucosylceramide ameliorates inflammatory dry-skin condition in chronic oxazolone-induced irritant contact dermatitis in the mouse ear. Journal of dermatological science 20120801
A facile and ecofriendly functionalization of multiwalled carbon nanotubes by an old mesoionic compound. Chemical communications (Cambridge, England) 20120711
Nanoparticle-based clodronate delivery mitigates murine experimental colitis. Journal of controlled release : official journal of the Controlled Release Society 20120628
The cannabinoid receptor-2 is involved in allergic inflammation. Life sciences 20120606
The development of T cell-dominated inflammatory responses induced by sodium lauryl sulphate in mouse oral mucosa. Archives of oral biology 20120601
Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. Colloids and surfaces. B, Biointerfaces 20120601
A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1. Mutation research 20120601
Structural influences on preferential oxazolone versus diketopiperazine b(2+) ion formation for histidine analogue-containing peptides. The journal of physical chemistry. A 20120503
Studies of cell signaling in a reconstructed human epidermis exposed to sensitizers: IL-8 synthesis and release depend on EGFR activation. Archives of dermatological research 20120501
Microbial exposure during early life has persistent effects on natural killer T cell function. Science (New York, N.Y.) 20120427
Identification of contact and respiratory sensitizers according to IL-4 receptor α expression and IL-2 production. Toxicology and applied pharmacology 20120415
Tetramethylpyrazine attenuates PPAR-γ antagonist-deteriorated oxazolone-induced colitis in mice. Molecular medicine reports 20120301
Disfavoring macrocycle b fragments by constraining torsional freedom: the 'twisted' case of QWFGLM b6. Journal of the American Society for Mass Spectrometry 20120301
Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity. Inflammation 20120201
Spectroscopic evidence for an oxazolone structure in anionic b-type peptide fragments. Journal of the American Society for Mass Spectrometry 20120201
Cutting edge: persistence of increased mast cell numbers in tissues links dermatitis to enhanced airway disease in a mouse model of atopy. Journal of immunology (Baltimore, Md. : 1950) 20120115
Effects of lactoferrin on elicitation of the antigen-specific cellular and humoral cutaneous response in mice. Postepy higieny i medycyny doswiadczalnej (Online) 20120112
Highly diastereoselective and enantioselective Michael addition of 5H-oxazol-4-ones to α,β-unsaturated ketones catalyzed by a new bifunctional organocatalyst with broad substrate scope and applicability. Chemical communications (Cambridge, England) 20120111
Palladium-catalyzed allylic alkylation of carboxylic acid derivatives: N-acyloxazolinones as ester enolate equivalents. Angewandte Chemie (International ed. in English) 20120102
B cells that produce immunoglobulin E mediate colitis in BALB/c mice. Gastroenterology 20120101
Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120101
Immunization induces activation of bone marrow eosinophils required for plasma cell survival. European journal of immunology 20120101
Novel immunomodulators based on an oxazolin-2-one-4-carboxamide scaffold. Bioorganic & medicinal chemistry letters 20120101
Synthesis of 2-furyl-4-arylidene-5(4H)-oxazolones as new potent antibacterial agents against phyto-pathogenic and nitrifying bacteria. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101
Immunosuppressive effect of prolactin-induced protein. Chemical immunology and allergy 20120101
High dose dietary pyridoxine induces T-helper type 1 polarization and decreases contact hypersensitivity response to fluorescein isothiocyanate in mice. Biological & pharmaceutical bulletin 20120101
A computational study on thiourea analogs as potent MK-2 inhibitors. International journal of molecular sciences 20120101
C-terminal de novo sequencing of peptides using oxazolone-based derivatization with bromine signature. Analytical biochemistry 20111215
Is there a typical germinal center? A large-scale immunohistological study on the cellular composition of germinal centers during the hapten-carrier-driven primary immune response in mice. Journal of immunology (Baltimore, Md. : 1950) 20111215
Oxazolone (OXA) is a respiratory allergen in Brown Norway rats. Toxicology 20111128
Jadomycins derived from the assimilation and incorporation of norvaline and norleucine. Journal of natural products 20111128
Topical herbal extract (Huangdang mixture) exhibits both preventive and therapeutic effects in murine acute irritant contact dermatitis. International journal of dermatology 20111101
Mast cell interleukin-2 production contributes to suppression of chronic allergic dermatitis. Immunity 20111028
Amphiphilic allylation of arylidene-1,3-oxazol-5(4H)-one using bis-π-allylpalladium complexes: an approach to synthesis of cyclohexyl and cyclohexenyl α-amino acids. Organic & biomolecular chemistry 20111021
Neonatal exposure to UVR alters skin immune system development, and suppresses immunity in adulthood. Immunology and cell biology 20111001
Regioselective orthopalladation of (Z)-2-aryl-4-arylidene-5(4H)-oxazolones: scope, kinetico-mechanistic, and density functional theory studies of the C-H bond activation. Inorganic chemistry 20110905
Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis. The Journal of investigative dermatology 20110901
Poly(3-alkylthiophenes): new sorption materials for solid phase microextraction of drugs isolated from human plasma. Analytical and bioanalytical chemistry 20110901
Diagnosing the protonation site of b2 peptide fragment ions using IRMPD in the X-H (X = O, N, and C) stretching region. Journal of the American Society for Mass Spectrometry 20110901
Regioselective 1,3-dipolar cycloaddition of phenanthrolinium N-ylides to substituted arylidene oxazolones. Molecular diversity 20110801
Mycobacterium bovis Bacillus Calmette-Guérin killed by extended freeze-drying reduces colitis in mice. Gastroenterology 20110801
Pathway analysis of gene expression in local lymph nodes draining skin exposed to three different sensitizers. Journal of applied toxicology : JAT 20110701
Diagnostic NH and OH vibrations for oxazolone and diketopiperazine structures: b2 from protonated triglycine. Journal of the American Society for Mass Spectrometry 20110701
Rhodium-catalyzed decarboxylative cycloaddition route to substituted anilines. The Journal of organic chemistry 20110603
Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. The Journal of clinical investigation 20110601
Towards understanding the tandem mass spectra of protonated oligopeptides. 2: The proline effect in collision-induced dissociation of protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp). Journal of the American Society for Mass Spectrometry 20110601
Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages. The Journal of clinical investigation 20110502
Variable impact of CD39 in experimental murine colitis. Digestive diseases and sciences 20110501
Novel affinity ligands for chromatography using combinatorial chemistry. Combinatorial chemistry & high throughput screening 20110501
An important role of lymphatic vessel activation in limiting acute inflammation. Blood 20110428
Oral administration of ginsenoside Rh1 inhibits the development of atopic dermatitis-like skin lesions induced by oxazolone in hairless mice. International immunopharmacology 20110401
TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery. Journal of dermatological science 20110401
β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway. The American journal of pathology 20110301
IL-33 activates B1 cells and exacerbates contact sensitivity. Journal of immunology (Baltimore, Md. : 1950) 20110215
New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation. Organic & biomolecular chemistry 20110207
The role of mitogen- and stress-activated protein kinase 1 and 2 in chronic skin inflammation in mice. Experimental dermatology 20110201
Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice. Journal of pharmacological sciences 20110101
Beneficial effects of pseudoceramide-containing physiologic lipid mixture as a vehicle for topical steroids. European journal of dermatology : EJD 20110101
Differential effects of peptidoglycan recognition proteins on experimental atopic and contact dermatitis mediated by Treg and Th17 cells. PloS one 20110101
Chemical basis for the extreme skin sensitization potency of (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one. Chemical research in toxicology 20101220
Comment on 'Deoxyuridine triphosphate incorporation during somatic hypermutation of mouse VkOx genes after immunization with phenyloxazolone'. Journal of immunology (Baltimore, Md. : 1950) 20101215
Absence of CCR4 exacerbates skin inflammation in an oxazolone-induced contact hypersensitivity model. The Journal of investigative dermatology 20101201
Exacerbation of oxazolone colitis by infection with the helminth Hymenolepis diminuta: involvement of IL-5 and eosinophils. The American journal of pathology 20101201
Gas-phase structure and fragmentation pathways of singly protonated peptides with N-terminal arginine. The journal of physical chemistry. B 20101125
Are the majority of a(2)-ions cyclic? Physical chemistry chemical physics : PCCP 20101107
Pituitary adenylate cyclase-activating polypeptide deficiency enhances oxazolone-induced allergic contact dermatitis in mice. Journal of molecular neuroscience : MN 20101101
Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress. The Journal of investigative dermatology 20101101
Deoxyuridine triphosphate incorporation during somatic hypermutation of mouse VkOx genes after immunization with phenyloxazolone. Journal of immunology (Baltimore, Md. : 1950) 20101015
Developments in nonsteroidal antiandrogens targeting the androgen receptor. ChemMedChem 20101004
Oxazolone-induced over-expression of focal adhesion kinase in colonic epithelial cells of colitis mouse model. FEBS letters 20100924
Preventive effects of black tea theaflavins against mouse type IV allergy. Journal of the science of food and agriculture 20100901
Licochalcone E reduces chronic allergic contact dermatitis and inhibits IL-12p40 production through down-regulation of NF-kappa B. International immunopharmacology 20100901
Upregulation of cathepsin S in psoriatic keratinocytes. Experimental dermatology 20100801
Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology 20100801
Oxazolone versus macrocycle structures for Leu-enkephalin b2-b4: insights from infrared multiple-photon dissociation spectroscopy and gas-phase hydrogen/deuterium exchange. Journal of the American Society for Mass Spectrometry 20100801
Immunohistological comparison of cutaneous pathology of three representative murine atopic dermatitis models. Journal of dermatological science 20100701
Kinetics of local tissue and regional lymph node IL-2 and IFN-gamma responses in experimental oral mucosa and skin contact sensitivity in mice. Scandinavian journal of immunology 20100701
Intravital imaging of IL-1beta production in skin. The Journal of investigative dermatology 20100601
Immunosuppressive effect of prolactin-induced protein: a new insight into its local and systemic role in chronic allergic contact dermatitis. The British journal of dermatology 20100601
[Effects of Bawei Xilei San on mice with oxazolone-induced colitis and the mechanisms]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100601
Enantioselective organocatalytic addition of oxazolones to 1,1-bis(phenylsulfonyl)ethylene: a convenient asymmetric synthesis of quaternary alpha-amino acids. Chemistry (Weinheim an der Bergstrasse, Germany) 20100510
Xanthohumol inhibits IL-12 production and reduces chronic allergic contact dermatitis. International immunopharmacology 20100501
A 3D-pharmacophore model for sigma2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives. Bioorganic & medicinal chemistry letters 20100501
Synthesis of 3,4,5-trisubstituted-1,2,4-triazoles. Chemical reviews 20100414
Efficient and regioselective synthesis of 5-hydroxy-2-isoxazolines: versatile synthons for isoxazoles, beta-lactams, and gamma-amino alcohols. The Journal of organic chemistry 20100319
The anti-inflammatory potency of dexamethasone is determined by the route of application in vivo. Immunology letters 20100310
Abrogation of high-affinity IgE receptor-mediated mast cell activation at the effector phase prevents contact hypersensitivity to oxazolone. The Journal of investigative dermatology 20100301
Visualizing CD4 T-cell migration into inflamed skin and its inhibition by CCR4/CCR10 blockades using in vivo imaging model. The British journal of dermatology 20100301
OsO4-mediated dihydroxylation of meso-tetraphenylporphyrin N-oxide and transformation of the resulting diolchlorin N-oxide regioisomers. The Journal of organic chemistry 20100219
Asymmetric aza-Mannich addition of oxazolones to N-tosyl aldimines: synthesis of chiral alpha-disubstituted alpha,beta-diamino acids. Organic letters 20100219
Oxazolone cycloadducts as heterocyclic scaffolds for alkaloid construction: synthesis of (+/-)-2-epi-pumiliotoxin C. The Journal of organic chemistry 20100205
Nickel/bis(oxazoline)-catalyzed asymmetric Kumada reactions of alkyl electrophiles: cross-couplings of racemic alpha-bromoketones. Journal of the American Chemical Society 20100203
Inhibition of delayed-type hypersensitivity by Cucurbitacin R through the curbing of lymphocyte proliferation and cytokine expression by means of nuclear factor AT translocation to the nucleus. The Journal of pharmacology and experimental therapeutics 20100201
Broad volume distributions indicate nonsynchronized growth and suggest sudden collapses of germinal center B cell populations. Journal of immunology (Baltimore, Md. : 1950) 20100201
The traditional herbal medicine saireito exerts its inhibitory effect on murine oxazolone-induced colitis via the induction of Th1-polarized immune responses in the mucosal immune system of the colon. International archives of allergy and immunology 20100101
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators. The Journal of allergy and clinical immunology 20100101
Topical 'Sydney' propolis protects against UV-radiation-induced inflammation, lipid peroxidation and immune suppression in mouse skin. International archives of allergy and immunology 20100101
Therapeutic efficacy and immunological response of CCL5 antagonists in models of contact skin reaction. PloS one 20100101
Assay systems for measurement of anti-inflammatory activity. Methods in molecular biology (Clifton, N.J.) 20100101
Pharmacological characterization of itch-associated response induced by repeated application of oxazolone in mice. Journal of pharmacological sciences 20100101
[Paeoniflorin increases beta-defensin expression and attenuates lesion in the colonic mucosa from mice with oxazolone-induced colitis]. Yao xue xue bao = Acta pharmaceutica Sinica 20100101
Effect of peptide fragment size on the propensity of cyclization in collision-induced dissociation: oligoglycine b(2)-b(8). Journal of the American Chemical Society 20091230
Evidence of diketopiperazine and oxazolone structures for HA b2+ ion. Journal of the American Chemical Society 20091209
Eukaryotic DNA polymerases alpha, beta and epsilon incorporate guanine opposite 2,2,4-triamino-5(2H)-oxazolone. Chembiochem : a European journal of chemical biology 20091102
Oxazolone-induced enterocolitis in zebrafish depends on the composition of the intestinal microbiota. Gastroenterology 20091101
Gene expression profiles and pathways in skin inflammation induced by three different sensitizers and an irritant. Toxicology letters 20091028
Anti-inflammatory and barrier protecting effect of Lithospermum erythrorhizon extracts in chronic oxazolone-induced murine atopic dermatitis. Journal of dermatological science 20091001
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. The Journal of allergy and clinical immunology 20090901
Oxazolone-induced delayed type hypersensitivity reaction in the adult yucatan pigs. A useful model for drug development and validation. Toxins 20090901
Chemically induced mouse models of colitis. Current protocols in pharmacology 20090901
Infrared spectroscopy of fragments of protonated peptides: direct evidence for macrocyclic structures of b5 ions. Journal of the American Chemical Society 20090819
Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice. Proceedings of the National Academy of Sciences of the United States of America 20090804
Enantioseparation of benzoxazolinone aminoalcohols and their aminoketone precursors, potential adrenergic ligands, by analytical and preparative liquid chromatography on amylose chiral stationary phases and characterization of the enantiomers. Chirality 20090801
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis. The Journal of investigative dermatology 20090701
Biomechanical changes in oxazolone-induced colitis in BALB/C mice. Journal of biomechanics 20090511
Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats. World journal of gastroenterology 20090421
Infrared spectroscopy of fragments from doubly protonated tryptic peptides. Chemphyschem : a European journal of chemical physics and physical chemistry 20090414
Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice. The Journal of investigative dermatology 20090401
The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases. Genes and immunity 20090401
Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. The Journal of allergy and clinical immunology 20090401
Increased cell proliferation in spleen and lymph nodes peripheral to contact allergen application site. Toxicology 20090329
A new method proposed for the determination of absolute configurations of alpha-amino acids. Magnetic resonance in chemistry : MRC 20090301
Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models. International immunopharmacology 20090301
Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4(+) CD25(+) regulatory T cells. Journal of dermatological science 20090301
Administration of Ag85B showed therapeutic effects to Th2-type cytokine-mediated acute phase atopic dermatitis by inducing regulatory T cells. Archives of dermatological research 20090201
Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. Gastroenterology 20090201
Spectroscopic evidence for an oxazolone structure of the b(2) fragment ion from protonated tri-alanine. Journal of the American Society for Mass Spectrometry 20090201
Pectin/Kollicoat SR30D isolated films for colonic delivery [I]: a comparison of normal and colitis-induced models to assess the efficiency of microbially triggered drug delivery. The Journal of pharmacy and pharmacology 20090201
Vitamin D3 deficiency enhances contact hypersensitivity in male but not in female mice. Cellular immunology 20090101
Morpholinone mediated oxazolone-free C-terminus amide coupling permitting a convergent strategy for peptide synthesis. Journal of peptide science : an official publication of the European Peptide Society 20090101
To b or not to b: the ongoing saga of peptide b ions. Mass spectrometry reviews 20090101
IRMPD spectroscopy shows that AGG forms an oxazolone b2+ ion. Journal of the American Chemical Society 20081231
Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice. International immunopharmacology 20081220
Dodecatungstophosphoric acid (H3PW 12O40), samarium and ruthenium (III) chloride catalyzed synthesis of unsaturated 2-phenyl-5(4H)-oxazolone derivatives under solvent-free conditions. Molecules (Basel, Switzerland) 20081218
Why are a(3) ions rarely observed? Journal of the American Society for Mass Spectrometry 20081201
Introducing N-glycans into natural products through a chemoenzymatic approach. Carbohydrate research 20081124
Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity. Archives of dermatological research 20081101
Studies on the selective trifluoroacetolytic scission of native peptaibols and model peptides using HPLC and ESI-CID-MS. Chemistry & biodiversity 20081101
The role of IL-13 and NK T cells in experimental and human ulcerative colitis. Mucosal immunology 20081101
NMR, mass spectrometry and chemical evidence reveal a different chemical structure for methanobactin that contains oxazolone rings. Journal of the American Chemical Society 20080924
Organocatalytic asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids and derivatives. Journal of the American Chemical Society 20080910
Synthesis, characterization and in vitro antibacterial activity of new steroidal 5-en-3-oxazolo and thiazoloquinoxaline. European journal of medicinal chemistry 20080901
Protease-activated receptor-2 activation: a major actor in intestinal inflammation. Gut 20080901
Transforming growth factor-beta/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity. The British journal of dermatology 20080901
Potent CCR4 antagonists: synthesis, evaluation, and docking study of 2,4-diaminoquinazolines. Bioorganic & medicinal chemistry 20080901
Characterization of langerhans cells in epidermal sheets along the body of Armadillo (Dasypus novemcinctus). Veterinary immunology and immunopathology 20080815
Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models. Experimental dermatology 20080801
Topically applied diterpenoids from Egletes viscosa (Asteraceae) attenuate the dermal inflammation in mouse ear induced by tetradecanoylphorbol 13-acetate- and oxazolone. Biological & pharmaceutical bulletin 20080801
Simvastatin attenuates trinitrobenzene sulfonic acid-induced colitis, but not oxazalone-induced colitis. Digestive diseases and sciences 20080701
The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6. The Journal of clinical investigation 20080701
Alcohol uncaging with fluorescence reporting: evaluation of o-acetoxyphenyl methyloxazolone precursors. Organic letters 20080619
Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice. Gastroenterology 20080601
Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response. The American journal of pathology 20080601
Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppression. Photodermatology, photoimmunology & photomedicine 20080601
Strategies to cure experimental autoimmune colitis using antigen-specific Foxp3+ regulatory T cells. Gastroenterology 20080601
Thymus-independent type 2 antigen induces a long-term IgG-related network memory. Molecular immunology 20080501
Synthesis of tert-alkyl amino hydroxy carboxylic esters via an intermolecular ene-type reaction of oxazolones and enol ethers. Organic letters 20080306
Essential role of CCR6 in directing activated T cells to the skin during contact hypersensitivity. The Journal of investigative dermatology 20080301
CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli. European journal of immunology 20080301
IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. Journal of leukocyte biology 20080201
Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine. The Journal of organic chemistry 20080201
A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology 20080201
Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin. European journal of pharmacology 20080114
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. The Journal of investigative dermatology 20080101
Estrogen receptor-beta signaling protects epidermal cytokine expression and immune function from UVB-induced impairment in mice. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080101
N-tosyloxycarbamates as reagents in rhodium-catalyzed C-H amination reactions. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Aldol reactions between L-erythrulose derivatives and chiral alpha-amino and alpha-fluoro aldehydes: competition between Felkin-Anh and Cornforth transition states. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Asymmetric 1,4-addition of oxazolones to nitroalkenes by bifunctional cinchona alkaloid thiourea organocatalysts: synthesis of alpha,alpha-disubstituted alpha-amino acids. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
In vitro differentiation of skin sensitizers by cell signaling pathways. Toxicology 20071205
Demethylnobiletin inhibits delayed-type hypersensitivity reactions, human lymphocyte proliferation and cytokine production. British journal of pharmacology 20071201
Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease. World journal of gastroenterology 20071114
Asymmetric Friedel-Crafts alkylation of methoxyfuran with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline)-Zn(II) complexes. Organic letters 20071108
Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity. Contact dermatitis 20071101
Expression of chemokine receptor CCR4 and its ligands (CCL17 and CCL22) in murine contact hypersensitivity. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20071101
T cells specific to hapten carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodies. International immunology 20071001
The diverse chemistry of oxazol-5-(4H)-ones. Chemical Society reviews 20070901
Stereochemical integrity of oxazolone ring-containing jadomycins. Chembiochem : a European journal of chemical biology 20070709
FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions. Molecular immunology 20070701
Vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK 222584 inhibits both the induction and elicitation phases of contact hypersensitivity. The Journal of dermatology 20070701
Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis. The Journal of investigative dermatology 20070601
The 'azirine/oxazolone method' in peptaibol synthesis: preparation of a derivative of trichotoxin A-50 (G). Chemistry & biodiversity 20070601
(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18. The Journal of pharmacology and experimental therapeutics 20070501
Interactions between CD47 and thrombospondin reduce inflammation. Journal of immunology (Baltimore, Md. : 1950) 20070501
Phase-dependent roles of E-selectin during chronic contact hypersensitivity responses. The American journal of pathology 20070501
Inhibition of the pro-inflammatory mediators' production and anti-inflammatory effect of the iridoid scrovalentinoside. Journal of ethnopharmacology 20070404
Toward iron sensors: bioinspired tripods based on fluorescent phenol-oxazoline coordination sites. Inorganic chemistry 20070402
Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis. Gut 20070401
Helminth infection enhances disease in a murine TH2 model of colitis. Gastroenterology 20070401
Intermolecular ene reactions utilizing oxazolones and enol ethers. Journal of the American Chemical Society 20070321
Ligand-dependent catalytic cycle and role of styrene in nickel-catalyzed anhydride cross-coupling: evidence for turnover-limiting reductive elimination. Journal of the American Chemical Society 20070307
Antigen-specific immunoglobulin E+ B cells are preferentially localized within germinal centres. Immunology 20070301
Remission-inducing effect of anti-TNF monoclonal antibody in TNBS colitis: mechanisms beyond neutralization? Inflammatory bowel diseases 20070301
New insight into the inhibition of the inflammatory response to experimental delayed-type hypersensitivity reactions in mice by scropolioside A. European journal of pharmacology 20070126
Highly enantioselective and diastereoselective 1,3-dipolar cycloaddition reactions between azomethine imines and 3-acryloyl-2-oxazolidinone catalyzed by binaphthyldiimine-Ni(II) complexes. Organic letters 20070104
Chemically induced mouse models of intestinal inflammation. Nature protocols 20070101
Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. Journal of immunology (Baltimore, Md. : 1950) 20061215
Enhancement of MALDI-MS spectra of C-terminal peptides by the modification of proteins via an active ester generated in situ from an oxazolone. Analytical chemistry 20061115
Detection of vascular expression of E-selectin in vivo with MR imaging. Radiology 20061101
Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during contact hypersensitivity in mice. The American journal of pathology 20061101
Overexpression of CIITA in T cells aggravates Th2-mediated colitis in mice. Journal of Korean medical science 20061001
Oxazolones: new tyrosinase inhibitors; synthesis and their structure-activity relationships. Bioorganic & medicinal chemistry 20060901
Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. Journal of immunology (Baltimore, Md. : 1950) 20060901
Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models. Biological & pharmaceutical bulletin 20060901
Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents. Journal of medicinal chemistry 20060824
Inhibitory effect of ginsenoside Rg5 and its metabolite ginsenoside Rh3 in an oxazolone-induced mouse chronic dermatitis model. Archives of pharmacal research 20060801
Induction of regulatory T cells by leflunomide in a murine model of contact allergen sensitivity. The Journal of investigative dermatology 20060701
T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nature immunology 20060501
Synthesis of novel benzofuran isoxazolines as protein tyrosine phosphatase 1B inhibitors. Bioorganic & medicinal chemistry letters 20060415
Stereoselective synthesis of benzomorphan derivatives with perpivaloylated galactose as the chiral auxiliary. Angewandte Chemie (International ed. in English) 20060410
Synthesis and biological evaluation of simplified mycothiazole analogues. Bioorganic & medicinal chemistry letters 20060301
The effects of ginsenoside Re and its metabolite, ginsenoside Rh1, on 12-O-tetradecanoylphorbol 13-acetate- and oxazolone-induced mouse dermatitis models. Planta medica 20060301
Synthesis and spectroscopic properties of 4-ethoxymethylene-2-(1)-naphthyl-5(4H)-oxazolone-labeled fluorescent peptides. Biopolymers 20060205
IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nature medicine 20060101
Investigation of gas phase ion structure for proline-containing b(2) ion. Journal of the American Society for Mass Spectrometry 20060101
Pharmacokinetics of 7-carboxymethyloxy-3',4',5-trimethoxy flavone (DA-6034), a derivative of flavonoid, in mouse and rat models of chemically-induced inflammatory bowel disease. The Journal of pharmacy and pharmacology 20060101
Toll-like receptor ligands reverse suppression of contact hypersensitivity reactions induced by epicutaneous immunization with protein antigen. International archives of allergy and immunology 20060101
Evaluation of an ex vivo murine local lymph node assay: multiple endpoint comparison. Journal of applied toxicology : JAT 20060101
Interleukin 5 plays an essential role in elicitation of contact sensitivity through dual effects on eosinophils and B-1 cells. International archives of allergy and immunology 20060101
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist. Drugs in R&D 20060101
Well-defined azlactone-functionalized (co)polymers on a solid support: synthesis via supported living radical polymerization and application as nucleophile scavengers. Journal of combinatorial chemistry 20060101
Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice. Pharmacology 20051201
Novel and expanded jadomycins incorporating non-proteogenic amino acids. Bioorganic & medicinal chemistry letters 20051201
Evidence for a novel protective role of the vanilloid TRPV1 receptor in a cutaneous contact allergic dermatitis model. Journal of neuroimmunology 20051201
Simple b ions have cyclic oxazolone structures. A neutralization-reionization mass spectrometric and computational study of oxazolone radicals. Journal of the American Society for Mass Spectrometry 20051201
Wavelength dependence of optical action potentials in the isolated rat atrium. The Japanese journal of physiology 20051201
Quantitation of four guanine oxidation products from reaction of DNA with varying doses of peroxynitrite. Chemical research in toxicology 20051201
The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice. European journal of pharmacology 20051107
Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase. The Journal of pharmacology and experimental therapeutics 20051101
Efficient synthesis of chiral beta-seleno amides via ring-opening reaction of 2-oxazolines and their application in the palladium-catalyzed asymmetric allylic alkylation. The Journal of organic chemistry 20051028
Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. The Journal of pharmacology and experimental therapeutics 20051001
Stereoselective acylation of a racemic amine with C(alpha)-methyl phenylglycine-based dipeptide 5(4H)-oxazolones. Chirality 20051001
Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response. Inflammatory bowel diseases 20050901
Dakin-West trick in the design of novel 2-alkyl(aralkyl) derivatives of oxazolo[3,2-a]pyridines. Molecules (Basel, Switzerland) 20050901
Highly efficient endoglycosidase-catalyzed synthesis of glycopeptides using oligosaccharide oxazolines as donor substrates. Journal of the American Chemical Society 20050713
Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis. International immunopharmacology 20050701
[Study the effect and mechanism of thalidomide in model of inflammatory bowed disease]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050701
Effect of chunghyuldan in chronic oxazolone-induced mouse dermatitis. Biological & pharmaceutical bulletin 20050601
Lipopolymers from new 2-substituted-2-oxazolines for artificial cell membrane constructs. Macromolecular bioscience 20050523
Origin of the heterogeneous distribution of the yield of guanyl radical in UV laser photolyzed DNA. Biophysical journal 20050401
CD1d and CD1d-restricted iNKT-cells play a pivotal role in contact hypersensitivity. Experimental dermatology 20050401
Oxidative stress in mouse skin following application of contact allergenic 5-chloro-2-methyl-4-isothiazolin-3-one and oxazolone. Contact dermatitis 20050301
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein. Blood 20050215
Disturbances in epithelial ionic secretion in different experimental models of colitis. Life sciences 20050211
Further studies on a mixture of fatty acids from sugar cane (Saccharum officinarum) wax oil in animal models of hypersensitivity. Planta medica 20050201
Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines. Organic & biomolecular chemistry 20050107
Antibody buffering of a ligand in vivo. Proceedings of the National Academy of Sciences of the United States of America 20050104
Regulatory cells induced by feeding TNP-haptenated colonic protein cross-protect mice from colitis induced by an unrelated hapten. Inflammatory bowel diseases 20050101
Mass spectrometric study of substituted alpha-acylaminocinnamic acids derived from partial hydrolysis of 5(4H)-oxazolones. Rapid communications in mass spectrometry : RCM 20050101
Immune sensitization in the skin is enhanced by antigen-independent effects of IgE on mast cells. Novartis Foundation symposium 20050101
Enantioselective synthesis of six-membered palladacycles having metal-bound stereogenic carbons: isolation and reactivity of palladacycles containing readily accessible beta-hydrogens. Journal of the American Chemical Society 20041229
Effects of olopatadine hydrochloride, an antihistamine drug, on skin inflammation induced by repeated topical application of oxazolone in mice. The British journal of dermatology 20041201
The intensity of neutrophil infiltration controls the number of antigen-primed CD8 T cells recruited into cutaneous antigen challenge sites. Journal of leukocyte biology 20041101
B cells are not required for T cell priming in low zone tolerance to contact allergens and contact hypersensitivity. European journal of immunology 20041101
Oxazolone-induced colitis in BALB/C mice: a new method to evaluate the efficacy of therapeutic agents for ulcerative colitis. Journal of pharmacological sciences 20041101
Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials. Bioorganic & medicinal chemistry letters 20040920
Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping. The Journal of biological chemistry 20040730
Inhibitory Effects of the C-2 Epimeric Isomers of Tea Catechins on Mouse Type IV Allergy. Journal of agricultural and food chemistry 20040728
Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis. International immunopharmacology 20040701
Understanding thymus-independent antigen-induced reduction of thymus-dependent immune responses. Immunology 20040701
Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice. Toxicological sciences : an official journal of the Society of Toxicology 20040601
Melatonin blocks dexamethasone-induced immunosuppression in a seasonally breeding rodent Indian palm squirrel, Funambulus pennanti. Steroids 20040601
Potent and selective inhibitors of bacterial methionyl tRNA synthetase derived from an oxazolone-dipeptide scaffold. Bioorganic & medicinal chemistry letters 20040419
Structure-activity studies for a novel series of tricyclic dihydropyridopyrazolones and dihydropyridoisoxazolones as K(ATP) channel openers. Bioorganic & medicinal chemistry 20040415
Fragmentation of deprotonated N-benzoylpeptides: formation of deprotonated oxazolones. Journal of the American Society for Mass Spectrometry 20040401
Immune sensitization in the skin is enhanced by antigen-independent effects of IgE. Immunity 20040401
Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity. Journal of immunology (Baltimore, Md. : 1950) 20040115
Modulation of skin norepinephrine turnover by allergen sensitization: impact on contact hypersensitivity and T helper priming. The Journal of investigative dermatology 20040101
Anti-allergic activity of 18beta-glycyrrhetinic acid-3-O-beta-D-glucuronide. Archives of pharmacal research 20040101
Enhanced responses in matrix-assisted laser desorption/ionization mass spectrometry of peptides derivatized with arginine via a C-terminal oxazolone. Rapid communications in mass spectrometry : RCM 20040101
Oxazolone-induced murine model of ulcerative colitis. Chinese journal of digestive diseases 20040101
Galanin expression in a murine model of allergic contact dermatitis. Acta dermato-venereologica 20040101
Neuronal repellent Slit2 inhibits dendritic cell migration and the development of immune responses. Journal of immunology (Baltimore, Md. : 1950) 20031215
Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma. Toxicological sciences : an official journal of the Society of Toxicology 20031201
Regulatory effects of osteoprotegerin on cellular and humoral immune responses. Clinical immunology (Orlando, Fla.) 20031201
Exploring selectivity requirements for COX-2 versus COX-1 binding of 3,4-diaryloxazolones using E-state index. Bioorganic & medicinal chemistry letters 20031103
Elimination of water from the carboxyl group of GlyGlyH+. Journal of the American Society for Mass Spectrometry 20031001
Generation and function of reactive oxygen species in dendritic cells during antigen presentation. Journal of immunology (Baltimore, Md. : 1950) 20030915
Comparative study on the effects of ointments of tinidazole, hydrocortisone and clobetasol on animal models for inflammatory dermatitis in mice. Fukuoka igaku zasshi = Hukuoka acta medica 20030901
Ciprofloxacin-induced acute psychosis in a patient with multidrug-resistant tuberculosis. European psychiatry : the journal of the Association of European Psychiatrists 20030801
Genistein as an anti-inflammatory agent. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030801
Non-genetic inheritable potential of maternal antibodies. Vaccine 20030728
Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center. International immunology 20030701
Role of Fas/Fas ligand-mediated apoptosis in murine contact hypersensitivity. International immunopharmacology 20030701
Impaired contact hypersensitivity in macrophage migration inhibitory factor-deficient mice. European journal of immunology 20030601
Oxazolone and diclofenac-induced popliteal lymph node assay reactions are attenuated in mice orally pretreated with the respective compound: potential role for the induction of regulatory mechanisms following enteric administration. Toxicology and applied pharmacology 20030601
Assessment of cumulative allergen-activated lymph node cell proliferation using flow cytometry. Toxicological sciences : an official journal of the Society of Toxicology 20030501
L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. Journal of immunology (Baltimore, Md. : 1950) 20030415
Acute stress modulates the irritant component of sensitizers in allergic contact dermatitis: implications for exposure assessment. Toxicology and applied pharmacology 20030401
Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation. Toxicology 20030314
High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties. Journal of the American Chemical Society 20030212
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. The Journal of investigative dermatology 20030201
Dynamic deformation of migratory efferent lymph-derived cells 'trapped' in the inflammatory microcirculation. Journal of cellular physiology 20030101
Investigations into the immunomodulatory activity of Argyreia speciosa. Journal of ethnopharmacology 20030101
Fragmentation mechanisms in electron ionization mass spectrometry of some 2-alkyl- and 2-aryl-4-arylidene-5(4H)-oxazolones. Rapid communications in mass spectrometry : RCM 20030101
Synthesis of the protected 6-16 segment of zervamicin 11-2, an application of the azirine/oxazolone method. Journal of peptide science : an official publication of the European Peptide Society 20030101
Effects of FK506 (tacrolimus hydrate) on chronic oxazolone-induced dermatitis in rats. European journal of pharmacology 20021205
Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 20021101
Stimulation of regional lymphatic and blood flow by epicutaneous oxazolone. Journal of applied physiology (Bethesda, Md. : 1985) 20020901
Polymer-supported ferrocenyl oxazolines for the catalyzed highly enantioselective phenyl transfer to aldehydes. Bioorganic & medicinal chemistry letters 20020722
Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses. Toxicology and applied pharmacology 20020715
Novel bicyclic oxazolone derivatives as anti-angiogenic agents. Bioorganic & medicinal chemistry letters 20020603
Contribution of Langerhans cell-derived IL-18 to contact hypersensitivity. Journal of immunology (Baltimore, Md. : 1950) 20020401
Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin-1beta. Immunology 20020401
Intramolecular Diels-Alder reactions of N-substituted oxazolones. Chemical communications (Cambridge, England) 20020307
The selective triggering of CD40 on keratinocytes in vivo enhances cell-mediated immunity. European journal of immunology 20020301
Mechanism of action of combined short-term CTLA4Ig and anti-CD40 ligand in murine systemic lupus erythematosus. Journal of immunology (Baltimore, Md. : 1950) 20020215
Oxazolinone derivative of leucine for GC-MS: a sensitive and robust method for stable isotope kinetic studies of lipoproteins. Journal of lipid research 20020201
Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood 20020115
Biochemical changes in the efferent lymph plasma after oxazolone stimulation. Developmental and comparative immunology 20020101
Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. The Journal of investigative dermatology 20020101
Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Japanese journal of pharmacology 20020101
[18O]-labeled singlet oxygen as a tool for mechanistic studies of 8-oxo-7,8-dihydroguanine oxidative damage: detection of spiroiminodihydantoin, imidazolone and oxazolone derivatives. Biological chemistry 20020101
CD156 transgenic mice. Different responses between inflammatory types. Pathobiology : journal of immunopathology, molecular and cellular biology 20020101
Cyclosporin A exacerbates skin irritation induced by tributyltin by increasing nuclear factor kappa B activation. The Journal of investigative dermatology 20011201
A new highly fluorescent probe for monosaccharides based on a donor-acceptor diphenyloxazole. Chemical communications (Cambridge, England) 20011007
Focal topographic changes in inflammatory microcirculation associated with lymphocyte slowing and transmigration. American journal of physiology. Heart and circulatory physiology 20011001
N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis. The Journal of pharmacology and experimental therapeutics 20011001
Contact sensitivity reactions in the oral mucosa. Acta odontologica Scandinavica 20010801
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity. The Journal of investigative dermatology 20010701
Anti-inflammatory planar chiral [2.2]paracyclophaneacetic acid enantiomers. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010701
Anti-inflammatory and anti-allergic actions by oral administration of a perilla leaf extract in mice. Bioscience, biotechnology, and biochemistry 20010701
Hapten-specific tolerance induced by acute, low-dose ultraviolet B radiation of skin requires mast cell degranulation. European journal of immunology 20010601
Stimulatory effects of B7-related protein-1 on cellular and humoral immune responses in mice. Journal of immunology (Baltimore, Md. : 1950) 20010501
Analysis of gene expression induced by irritant and sensitizing chemicals using oligonucleotide arrays. International immunopharmacology 20010501
Enantioselectivity of recombinant Rhizomucor miehei lipase in the ring opening of oxazolin-5(4H)-ones. Protein engineering 20010401
Oral administration of recombinant cholera toxin subunit B inhibits IL-12-mediated murine experimental (trinitrobenzene sulfonic acid) colitis. Journal of immunology (Baltimore, Md. : 1950) 20010301
Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. Fitoterapia 20010301
Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism. Immunology 20010301
Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity. Blood 20010215
Signals that initiate somatic hypermutation of B cells in vitro. Journal of immunology (Baltimore, Md. : 1950) 20010215
Stochastic regulation of cell migration from the efferent lymph to oxazolone-stimulated skin. Journal of immunology (Baltimore, Md. : 1950) 20010201
Pineal modulation of thymus and immune function in a seasonally breeding tropical rodent, Funambulus pennanti. The Journal of experimental zoology 20010201
The IgE antigen receptor: a key regulator for the production of IgE antibodies. International archives of allergy and immunology 20010101
Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines. Acta biochimica Polonica 20010101
CD4+ Th1 and CD8+ type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity. Journal of immunology (Baltimore, Md. : 1950) 20001215
Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. The Journal of investigative dermatology 19940601
3-Dimethylphosphinothioyl-2(3H)-oxazolone (MPTO), a promising new reagent for racemization-free couplings. International journal of peptide and protein research 19930901
Effect of ETH615, an inhibitor of leukotriene synthesis and IL-8 gene expression, on murine dermatoses. Agents and actions 19930101
Variable effects of chemical allergens on serum IgE concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers. Journal of applied toxicology : JAT 19921001
Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19920201
Selective impairment of T lymphocyte activation following contact sensitization with oxazolone. International archives of allergy and applied immunology 19910101
Antigen-restricted antigenic competition induced by 2,4-dinitrochlorobenzene: association with depression of lymphocyte proliferation. International archives of allergy and applied immunology 19900101
Antigenic competition in the induction of contact sensitivity in the guinea pig. International archives of allergy and applied immunology 19850101
Fine specificity of the immune response to oxazolones III. Antibodies but not contact sensitivity specific for 2-furyloxazolone are controlled by an Igh-V gene in the mouse. European journal of immunology 19831201
A hapten-specific Ir gene. Journal of immunology (Baltimore, Md. : 1950) 19791001
Allergic contact dermatitis to low molecular weight allergens in the chicken. International archives of allergy and applied immunology 19760101

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