200,000+ products from a single source!
sales@angenechem.com
155233-30-0 | 4,5-Dihydro-4-(11-methoxy-8-methyl-1,5,7,13-tetradecatetraenyl)-2-(2-m ethylcyclopropyl)thiazole (1R-(1alpha(R*(1Z,5E,7E,11R*)),2alpha))-
CAS No: 155233-30-0 Catalog No: AG00AZOP MDL No:
Product Description
Catalog Number:
AG00AZOP
Chemical Name:
4,5-Dihydro-4-(11-methoxy-8-methyl-1,5,7,13-tetradecatetraenyl)-2-(2-m ethylcyclopropyl)thiazole (1R-(1alpha(R*(1Z,5E,7E,11R*)),2alpha))-
CAS Number:
155233-30-0
IUPAC Name:
(4R)-4-[(1Z,5E,7E,11R)-11-methoxy-8-methyltetradeca-1,5,7,13-tetraenyl]-2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazole
InChI:
InChI=1S/C23H35NOS/c1-5-11-21(25-4)15-14-18(2)12-9-7-6-8-10-13-20-17-26-23(24-20)22-16-19(22)3/h5,7,9-10,12-13,19-22H,1,6,8,11,14-17H2,2-4H3/b9-7+,13-10-,18-12+/t19-,20+,21-,22+/m0/s1
InChI Key:
LUEYTMPPCOCKBX-KWYHTCOPSA-N
Properties
Complexity:
561
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
4
Defined Bond Stereocenter Count:
3
Exact Mass:
373.244g/mol
Formal Charge:
0
Heavy Atom Count:
26
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
373.599g/mol
Monoisotopic Mass:
373.244g/mol
Rotatable Bond Count:
12
Topological Polar Surface Area:
46.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.1
Literature
| Title | Journal |
|---|---|
| Insights from the sea: structural biology of marine polyketide synthases. | Natural product reports 20121001 |
| Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. | The Journal of biological chemistry 20110422 |
| Metamorphic enzyme assembly in polyketide diversification. | Nature 20090604 |
| Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching. | The Journal of biological chemistry 20071207 |
| GNAT-like strategy for polyketide chain initiation. | Science (New York, N.Y.) 20071109 |
| Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. | Journal of the American Chemical Society 20060719 |
| A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. | Journal of medicinal chemistry 20050922 |
| Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula. | Journal of natural products 20040801 |
| High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole. | Journal of biomolecular screening 20030401 |
| Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A. | Journal of medicinal chemistry 20020425 |
Related Products
© 2019 Angene International Limited. All rights Reserved.