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15502-74-6

15502-74-6 | Arsenite (8CI,9CI)

CAS No: 15502-74-6 Catalog No: AG001NKD MDL No:

Product Description

Catalog Number:
AG001NKD
Chemical Name:
Arsenite (8CI,9CI)
CAS Number:
15502-74-6
Molecular Formula:
AsO3---
Molecular Weight:
122.9198
IUPAC Name:
arsorite
InChI:
InChI=1S/AsO3/c2-1(3)4/q-3
InChI Key:
OWTFKEBRIAXSMO-UHFFFAOYSA-N
SMILES:
[O-][As]([O-])[O-]
UNII:
N5509X556J

Properties

Complexity:
8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
122.906g/mol
Formal Charge:
-3  
Heavy Atom Count:
4  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
122.919g/mol
Monoisotopic Mass:
122.906g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
69.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite. Toxicological sciences : an official journal of the Society of Toxicology 20181001
MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA 20180401
Exposures to arsenite and methylarsonite produce insulin resistance and impair insulin-dependent glycogen metabolism in hepatocytes. Archives of toxicology 20171201
Impaired autophagic flux and p62-mediated EMT are involved in arsenite-induced transformation of L-02 cells. Toxicology and applied pharmacology 20171101
Arsenite Binds to the Zinc Finger Motif of TIP60 Histone Acetyltransferase and Induces Its Degradation via the 26S Proteasome. Chemical research in toxicology 20170918
The expression of keratin 6 is regulated by the activation of the ERK1/2 pathway in arsenite transformed human urothelial cells. Toxicology and applied pharmacology 20170915
Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue. Toxicology and applied pharmacology 20170915
Cell cycle pathway dysregulation in human keratinocytes during chronic exposure to low arsenite. Toxicology and applied pharmacology 20170915
Low concentration arsenite activated JAK2/STAT3 signal and increased proliferative factor expressions in SV-HUC-1cells after short and long time treatment. Environmental toxicology 20170901
Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity. Toxicology and applied pharmacology 20170815
MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells. Toxicology letters 20170815
Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway. Environmental toxicology 20170801
Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity. Chemical research in toxicology 20170717
Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability. Toxicology 20170715
Efflux Transporters Regulate Arsenite-Induced Genotoxicity in Double Negative and Double Positive T Cells. Toxicological sciences : an official journal of the Society of Toxicology 20170701
Environmentally relevant dose of arsenic interferes in functions of human monocytes derived dendritic cells. Toxicology letters 20170605
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells. Carcinogenesis 20170601
Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis. Toxicology letters 20170104
Arsenite-induced endoplasmic reticulum-dependent apoptosis through disturbance of calcium homeostasis in HBE cell line. Environmental toxicology 20170101
Knockout of arsenic (+3 oxidation state) methyltransferase results in sex-dependent changes in phosphatidylcholine metabolism in mice. Archives of toxicology 20161201
Role of the antioxidant defence system and telomerase in arsenic-induced genomic instability. Mutagenesis 20161101
From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans. Toxicological sciences : an official journal of the Society of Toxicology 20160801
Altered Hepatic Transport by Fetal Arsenite Exposure in Diet-Induced Fatty Liver Disease. Journal of biochemical and molecular toxicology 20160701
Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells. Archives of toxicology 20160401
Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F₂ male offspring via the F₁ male offspring. Journal of applied toxicology : JAT 20160101
Environmentally Relevant Concentrations of Arsenite Induce Dose-Dependent Differential Genotoxicity Through Poly(ADP-Ribose) Polymerase Inhibition and Oxidative Stress in Mouse Thymus Cells. Toxicological sciences : an official journal of the Society of Toxicology 20160101
Roles of oxidative stress and the ERK1/2, PTEN and p70S6K signaling pathways in arsenite-induced autophagy. Toxicology letters 20151215
Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation. Toxicological sciences : an official journal of the Society of Toxicology 20151201
Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic. Free radical biology & medicine 20151101
Coordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 gene. Biochimica et biophysica acta 20151001
Alteration of mammary gland development and gene expression by in utero exposure to arsenic. Reproductive toxicology (Elmsford, N.Y.) 20150701
Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein. Toxicology letters 20150318
Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PloS one 20150101
The Green Tea Component (-)-Epigallocatechin-3-Gallate Sensitizes Primary Endothelial Cells to Arsenite-Induced Apoptosis by Decreasing c-Jun N-Terminal Kinase-Mediated Catalase Activity. PloS one 20150101
Arsenic induced overexpression of inflammatory cytokines based on the human urothelial cell model in vitro and urinary secretion of individuals chronically exposed to arsenic. Chemical research in toxicology 20141117
Pathway of human AS3MT arsenic methylation. Chemical research in toxicology 20141117
Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes. Toxicology and applied pharmacology 20141115
Cardiac epithelial-mesenchymal transition is blocked by monomethylarsonous acid (III). Toxicological sciences : an official journal of the Society of Toxicology 20141101
AP-1 activation attenuates the arsenite-induced apoptotic response in human bronchial epithelial cells by up-regulating HO-1 expression. Biotechnology letters 20141001
Associations between arsenic species in exfoliated urothelial cells and prevalence of diabetes among residents of Chihuahua, Mexico. Environmental health perspectives 20141001
Molecular control of arsenite-induced apoptosis in Caenorhabditis elegans: roles of insulin-like growth factor-1 signaling pathway. Chemosphere 20141001
HuR regulates alternative splicing of the TRA2β gene in human colon cancer cells under oxidative stress. Molecular and cellular biology 20140801
Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis. Cell cycle (Georgetown, Tex.) 20140701
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB. Toxicology letters 20140605
β-catenin involvement in arsenite-induced VEGF expression in neuroblastoma SH-SY5Y cells. Environmental toxicology 20140601
Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20140401
Ogg1 genetic background determines the genotoxic potential of environmentally relevant arsenic exposures. Archives of toxicology 20140301
Arsenic-induced suppression of kidney cell proliferation and the transcriptional coregulator MAML1. Metallomics : integrated biometal science 20140301
Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair. Toxicology and applied pharmacology 20140115
NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity. Toxicology letters 20140113
Knockdown of p66Shc by siRNA injection rescues arsenite-induced developmental retardation in mouse preimplantation embryos. Reproductive toxicology (Elmsford, N.Y.) 20140101
The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase. PloS one 20140101
Effect of the ARG1 gene on arsenic resistance of 293T cells. Genetics and molecular research : GMR 20131219
Effects of arsenic on modification of promyelocytic leukemia (PML): PML responds to low levels of arsenite. Toxicology and applied pharmacology 20131215
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. Cell metabolism 20131203
Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells. Toxicology letters 20131009
Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells. Toxicology 20131004
Disruption of canonical TGFβ-signaling in murine coronary progenitor cells by low level arsenic. Toxicology and applied pharmacology 20131001
Taurine prevented cell cycle arrest and restored neurotrophic gene expression in arsenite-treated SH-SY5Y cells. Amino acids 20131001
Inorganic arsenic exposure induces E2F-dependent G0/G1 arrest via an increase in retinoblastoma family protein p130 in B-cell lymphoma A20 cells. Genes to cells : devoted to molecular & cellular mechanisms 20131001
Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation. Epigenetics 20131001
Maternal and early life arsenite exposure impairs neurodevelopment and increases the expression of PSA-NCAM in hippocampus of rat offspring. Toxicology 20130915
Epithelial to mesenchymal transition in arsenic-transformed cells promotes angiogenesis through activating β-catenin-vascular endothelial growth factor pathway. Toxicology and applied pharmacology 20130815
Phosphorylation of histone H3 at serine 10 has an essential role in arsenite-induced expression of FOS, EGR1 and IL8 mRNA in cultured human cell lines. Journal of applied toxicology : JAT 20130801
Expression of WWOX and FHIT is downregulated by exposure to arsenite in human uroepithelial cells. Toxicology letters 20130704
Arsenite suppression of BMP signaling in human keratinocytes. Toxicology and applied pharmacology 20130615
The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues. Biochemical and biophysical research communications 20130419
The inhibition of HIF-2α on the ATM/Chk-2 pathway is involved in the promotion effect of arsenite on benzo(a)pyrene-induced cell transformation. Toxicology letters 20130412
Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins. The Journal of biological chemistry 20130308
Differential regulation of M3/6 (DUSP8) signaling complexes in response to arsenite-induced oxidative stress. Cellular signalling 20130201
Effect of glucosamine and chitooligomer on the toxicity of arsenite against Escherichia coli. Carbohydrate polymers 20130102
HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing. The FEBS journal 20130101
Feedback regulations of miR-21 and MAPKs via Pdcd4 and Spry1 are involved in arsenite-induced cell malignant transformation. PloS one 20130101
Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism. Oxidative medicine and cellular longevity 20130101
Arsenite-induced stress signaling: modulation of the phosphoinositide 3'-kinase/Akt/FoxO signaling cascade. Redox biology 20130101
Rapid equilibrium kinetic analysis of arsenite methylation catalyzed by recombinant human arsenic (+3 oxidation state) methyltransferase (hAS3MT). The Journal of biological chemistry 20121109
Remodulation of central carbon metabolic pathway in response to arsenite exposure in Rhodococcus sp. strain NAU-1. Microbial biotechnology 20121101
Arsenite-induced autophagy is associated with proteotoxicity in human lymphoblastoid cells. Toxicology and applied pharmacology 20121015
Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20121001
Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione. Toxicology and applied pharmacology 20121001
Mechanisms underlying the inhibitory effects of arsenic compounds on protein tyrosine phosphatase (PTP). Toxicology and applied pharmacology 20120915
Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio. Toxicology and applied pharmacology 20120715
Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd²⁺ or As³⁺. Toxicology letters 20120707
Lysobacter arseniciresistens sp. nov., an arsenite-resistant bacterium isolated from iron-mined soil. International journal of systematic and evolutionary microbiology 20120701
A periplasmic arsenite-binding protein involved in regulating arsenite oxidation. Environmental microbiology 20120701
Polyamines inhibit the assembly of stress granules in normal intestinal epithelial cells regulating apoptosis. American journal of physiology. Cell physiology 20120701
Effects of arsenite and UVA-1 radiation on calcineurin signaling. Mutation research 20120701
Arsenite activates NFκB through induction of C-reactive protein. Toxicology and applied pharmacology 20120615
Proteomic analysis of arsenite - mediated multiple antibiotic resistance in Yersinia enterocolitica biovar 1A. Journal of basic microbiology 20120601
Hydroxyethyl disulfide as an efficient metabolic assay for cell viability in vitro. Toxicology in vitro : an international journal published in association with BIBRA 20120601
Quantitative imaging of arsenic and its species in goat following long term oral exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601
Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice. Archives of toxicology 20120601
Glutathione serves an extracellular defence function to decrease arsenite accumulation and toxicity in yeast. Molecular microbiology 20120601
Arsenite exposure altered the expression of NMDA receptor and postsynaptic signaling proteins in rat hippocampus. Toxicology letters 20120520
DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells. Toxicology letters 20120505
Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation. Free radical biology & medicine 20120501
Poly(ADP-ribose) polymerase-1 inhibition by arsenite promotes the survival of cells with unrepaired DNA lesions induced by UV exposure. Toxicological sciences : an official journal of the Society of Toxicology 20120501
Influence of glutathione chemical effectors in the response of maize to arsenic exposure. Journal of plant physiology 20120501
The endoplasmic reticulum is a target organelle for trivalent dimethylarsinic acid (DMAIII)-induced cytotoxicity. Toxicology and applied pharmacology 20120501
Chemical activation of a high-affinity glutamate transporter in human erythrocytes and its implications for malaria-parasite-induced glutamate uptake. Blood 20120412
Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. Analytica chimica acta 20120406
Arsenite promotes apoptosis and dysfunction in microvascular endothelial cells via an alteration of intracellular calcium homeostasis. Toxicology in vitro : an international journal published in association with BIBRA 20120401
Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. International immunopharmacology 20120401
Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes. Environmental health perspectives 20120401
Effects of arsenite stress on growth and proteome of Klebsiella pneumoniae. Journal of biotechnology 20120331
Arsenite-induced apoptosis of human neuroblastoma cells requires p53 but occurs independently of c-Jun. Neuroscience 20120329
Pathological, immunological and biochemical markers of subchronic arsenic toxicity in rats. Environmental toxicology 20120301
Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes. Drug metabolism and disposition: the biological fate of chemicals 20120301
Tudor-SN and ADAR1 are components of cytoplasmic stress granules. RNA (New York, N.Y.) 20120301
Effects of manganese and arsenic species on the level of energy related nucleotides in human cells. Metallomics : integrated biometal science 20120301
Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress. The Journal of biological chemistry 20120217
The Drosophila DUSP puckered is phosphorylated by JNK and p38 in response to arsenite-induced oxidative stress. Biochemical and biophysical research communications 20120210
Flexible bacterial strains that oxidize arsenite in anoxic or aerobic conditions and utilize hydrogen or acetate as alternative electron donors. Biodegradation 20120201
As(2)O (3) oxidation by vitamin C: cell culture studies. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20120201
Effects of arsenite on glutamate metabolism in primary cultured astrocytes. Toxicology in vitro : an international journal published in association with BIBRA 20120201
Methylated arsenic species in plants originate from soil microorganisms. The New phytologist 20120201
Potentiated homeopathic drug Arsenicum Album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenite-exposed bacteria Escherichia coli. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120201
Efflux permease CgAcr3-1 of Corynebacterium glutamicum is an arsenite-specific antiporter. The Journal of biological chemistry 20120102
Arsenic induced progesterone production in a caspase-3-dependent manner and changed redox status in preovulatory granulosa cells. Journal of cellular physiology 20120101
Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response. The Biochemical journal 20120101
Adsorption of arsenite and selenite using an inorganic ion exchanger based on Fe-Mn hydrous oxide. Journal of colloid and interface science 20120101
Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic. Toxicological sciences : an official journal of the Society of Toxicology 20120101
Deciphering the role of Paenibacillus strain Q8 in the organic matter recycling in the acid mine drainage of Carnoulès. Microbial cell factories 20120101
Cysteinyl-tRNA deacylation can be uncoupled from protein synthesis. PloS one 20120101
Novel plasmids and resistance phenotypes in Yersinia pestis: unique plasmid inventory of strain Java 9 mediates high levels of arsenic resistance. PloS one 20120101
EMT and stem cell-like properties associated with HIF-2α are involved in arsenite-induced transformation of human bronchial epithelial cells. PloS one 20120101
Urinary excretion of bilirubin oxidative metabolites in arsenite-treated mice. The Journal of toxicological sciences 20120101
Pathways of arsenic uptake and efflux. Current topics in membranes 20120101
Molecular changes during arsenic-induced cell transformation. Journal of cellular physiology 20111201
Junin virus infection impairs stress-granule formation in Vero cells treated with arsenite via inhibition of eIF2α phosphorylation. The Journal of general virology 20111201
Uptake and translocation of arsenite by Pteris vittata L.: effects of glycerol, antimonite and silver. Environmental pollution (Barking, Essex : 1987) 20111201
Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Drug metabolism and disposition: the biological fate of chemicals 20111201
Mouse arsenic (+3 oxidation state) methyltransferase genotype affects metabolism and tissue dosimetry of arsenicals after arsenite administration in drinking water. Toxicological sciences : an official journal of the Society of Toxicology 20111201
Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes. Toxicology and applied pharmacology 20111201
Interaction of arsenite with a zinc finger CCHC peptide: evidence for formation of an As-Zn-peptide mixed complex. Journal of inorganic biochemistry 20111201
Mechanisms of efficient arsenite uptake by arsenic hyperaccumulator Pteris vittata. Environmental science & technology 20111115
Oxidative modifications of proteins by sodium arsenite in human umbilical vein endothelial cells. Environmental toxicology 20111001
Arsenicals affect base excision repair by several mechanisms. Mutation research 20111001
Development of an inexpensive and sensitive method for the determination of low quantity of arsenic species in water samples by CPE-FAAS. Talanta 20110915
Arsenic transformation predisposes human skin keratinocytes to UV-induced DNA damage yet enhances their survival apparently by diminishing oxidant response. Toxicology and applied pharmacology 20110915
Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation. The Journal of biological chemistry 20110909
Accumulation, biotransformation, and biochemical responses after exposure to arsenite and arsenate in the estuarine polychaete Laeonereis acuta (Nereididae). Environmental science and pollution research international 20110901
X-ray crystal structure of arsenite-inhibited xanthine oxidase: μ-sulfido,μ-oxo double bridge between molybdenum and arsenic in the active site. Journal of the American Chemical Society 20110817
Arsenite exposure downregulates EAAT1/GLAST transporter expression in glial cells. Toxicological sciences : an official journal of the Society of Toxicology 20110801
In vitro study of intestinal transport of arsenite, monomethylarsonous acid, and dimethylarsinous acid by Caco-2 cell line. Toxicology letters 20110728
A transgenic Drosophila model for arsenic methylation suggests a metabolic rationale for differential dose-dependent toxicity endpoints. Toxicological sciences : an official journal of the Society of Toxicology 20110601
Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response. Biochemical and biophysical research communications 20110408
Realgar and realgar-containing Liu-Shen-Wan are less acutely toxic than arsenite and arsenate. Journal of ethnopharmacology 20110308
The mechanism of the polynucleotide phosphorylase-catalyzed arsenolysis of ADP. Biochimie 20110301
Effects of DNMT and MEK inhibitors on the expression of RECK, MMP-9, -2, uPA and VEGF in response to arsenite stimulation in human uroepithelial cells. Toxicology letters 20110225
Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression. Cellular and molecular life sciences : CMLS 20110201
Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT). Biochimie 20110201
Arsenic tolerances in rice (Oryza sativa) have a predominant role in transcriptional regulation of a set of genes including sulphur assimilation pathway and antioxidant system. Chemosphere 20110201
Arsenic stress activates MAP kinase in rice roots and leaves. Archives of biochemistry and biophysics 20110201
Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16. Toxicology letters 20110115
Rapid whole-cell sensing chip for low-level arsenite detection. Biosensors & bioelectronics 20110115
Subinhibitory arsenite concentrations lead to population dispersal in Thiomonas sp. PloS one 20110101
Involvement of c-Met- and phosphatidylinositol 3-kinase dependent pathways in arsenite-induced downregulation of catalase in hepatoma cells. Biological & pharmaceutical bulletin 20110101
A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae. The Journal of toxicological sciences 20110101
Modulation of early stress-related biomarkers in cytoplasm by the antioxidants silymarin and quercetin using a cellular model of acute arsenic poisoning. Basic & clinical pharmacology & toxicology 20101201
Hydrogen formation by an arsenate-reducing Pseudomonas putida, isolated from arsenic-contaminated groundwater in West Bengal, India. Applied microbiology and biotechnology 20101201
Characterization of a two-component signal transduction system that controls arsenite oxidation in the chemolithoautotroph NT-26. FEMS microbiology letters 20101201
Arsenite exposure in human lymphoblastoid cell lines induces autophagy and coordinated induction of lysosomal genes. Toxicology letters 20101130
SPARC gene expression is repressed in human urothelial cells (UROtsa) exposed to or malignantly transformed by cadmium or arsenite. Toxicology letters 20101130
Arsenite induces endothelial cell permeability increase through a reactive oxygen species-vascular endothelial growth factor pathway. Chemical research in toxicology 20101115
Non-enzymatic roles for the URE2 glutathione S-transferase in the response of Saccharomyces cerevisiae to arsenic. Archives of microbiology 20101101
New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT). Biochimie 20101001
Carcinogenic heavy metals replace Ca2+ for DNA binding and annealing activities of mono-ubiquitinated annexin A1 homodimer. Toxicology and applied pharmacology 20101001
Activity of Phase I and Phase II enzymes of the benzo[a]pyrene transformation pathway in zebrafish (Danio rerio) following waterborne exposure to arsenite. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100901
p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways. The Journal of biological chemistry 20100820
Mechanisms regulating the nuclear translocation of p38 MAP kinase. Journal of cellular biochemistry 20100815
Effects of exogenous GSH and methionine on methylation of inorganic arsenic in mice exposed to arsenite through drinking water. Environmental toxicology 20100801
Keratin 6 expression correlates to areas of squamous differentiation in multiple independent isolates of As(+3)-induced bladder cancer. Journal of applied toxicology : JAT 20100701
mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells. Environmental health perspectives 20100701
The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite. Toxicological sciences : an official journal of the Society of Toxicology 20100701
Severe systemic toxicity and urinary bladder cytotoxicity and regenerative hyperplasia induced by arsenite in arsenic (+3 oxidation state) methyltransferase knockout mice. A preliminary report. Toxicology and applied pharmacology 20100701
Sequential extraction method for speciation of arsenate and arsenite in mineral soils. Analytical chemistry 20100701
The JNK pathway modulates expression and phosphorylation of 4E-BP1 in MIN6 pancreatic beta-cells under oxidative stress conditions. Cell biochemistry and function 20100701
A sorption kinetics model for arsenic adsorption to magnetite nanoparticles. Environmental science and pollution research international 20100601
Calcium clearance and its energy requirements in cerebellar neurons. Cell calcium 20100601
Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells. The Journal of toxicological sciences 20100601
A vacuolar arsenite transporter necessary for arsenic tolerance in the arsenic hyperaccumulating fern Pteris vittata is missing in flowering plants. The Plant cell 20100601
Arsenite induces oxidative injury in rat brain: synergistic effect of iron. Annals of the New York Academy of Sciences 20100601
Caenorhabditis elegans bicarbonate transporter ABTS-1 is involved in arsenite toxicity and cholinergic signaling. Chemical research in toxicology 20100517
Arsenite down-regulates cytochrome P450 1A1 at the transcriptional and posttranslational levels in human HepG2 cells. Free radical biology & medicine 20100515
Arsenite causes down-regulation of Akt and c-Fos, cell cycle dysfunction and apoptosis in glutathione-deficient cells. Journal of cellular biochemistry 20100515
Protective effect of quercetin against arsenite-induced COX-2 expression by targeting PI3K in rat liver epithelial cells. Journal of agricultural and food chemistry 20100512
Arsenic-specific stem cell selection during malignant transformation. Journal of the National Cancer Institute 20100505
Arsenic promotes angiogenesis in vitro via a heme oxygenase-1-dependent mechanism. Toxicology and applied pharmacology 20100501
Arsenite induces apoptosis in human mesenchymal stem cells by altering Bcl-2 family proteins and by activating intrinsic pathway. Toxicology and applied pharmacology 20100501
Autophagy is the predominant process induced by arsenite in human lymphoblastoid cell lines. Toxicology and applied pharmacology 20100501
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. The Journal of biological chemistry 20100402
Arsenic detoxification potential of aox genes in arsenite-oxidizing bacteria isolated from natural and constructed wetlands in the Republic of Korea. Environmental geochemistry and health 20100401
Column studies on the evaluation of novel spacer granules for the removal of arsenite and arsenate from contaminated water. Bioresource technology 20100401
Opposing actions of insulin and arsenite converge on PKCdelta to alter keratinocyte proliferative potential and differentiation. Molecular carcinogenesis 20100401
Antioxidant potential of tea reduces arsenite induced oxidative stress in Swiss albino mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100401
Complexation of arsenite with phytochelatins reduces arsenite efflux and translocation from roots to shoots in Arabidopsis. Plant physiology 20100401
DNA microarray gene expression analysis of human vascular endothelial cells exposed to arsenite. The Journal of toxicological sciences 20100401
Arsenite suppression of involucrin transcription through AP1 promoter sites in cultured human keratinocytes. Toxicology and applied pharmacology 20100315
Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure. Toxicology and applied pharmacology 20100315
Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis. Toxicology letters 20100301
Comparative antioxidant profiling of tolerant and sensitive varieties of Brassica juncea L. to arsenate and arsenite exposure. Bulletin of environmental contamination and toxicology 20100301
Arsenite promotes centrosome abnormalities under a p53 compromised status induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Toxicology and applied pharmacology 20100215
Suppression of p53 and p21CIP1/WAF1 reduces arsenite-induced aneuploidy. Chemical research in toxicology 20100215
Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in HL-60 cells induced by arsenite treatment. Journal of proteome research 20100205
Intracellular redox imbalance and extracellular amino acid metabolic abnormality contribute to arsenic-induced developmental retardation in mouse preimplantation embryos. Journal of cellular physiology 20100201
Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice. Molecular and cellular biology 20100201
Phosphoproteomic profiling of arsenite-treated human small airway epithelial cells. Oncology reports 20100201
Role of signature lysines in the deviant walker a motifs of the ArsA ATPase. Biochemistry 20100119
Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells. Toxicology and applied pharmacology 20100115
Arsenite removal from waters by zero valent iron: batch and column tests. Chemosphere 20100101
Arsenic exposure transforms human epithelial stem/progenitor cells into a cancer stem-like phenotype. Environmental health perspectives 20100101
Multiple controls affect arsenite oxidase gene expression in Herminiimonas arsenicoxydans. BMC microbiology 20100101
eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PloS one 20100101
Arsenic exposure in utero and nonepidermal proliferative response in adulthood in Tg.AC mice. International journal of toxicology 20100101
Microbial oxidation of arsenite in a subarctic environment: diversity of arsenite oxidase genes and identification of a psychrotolerant arsenite oxidiser. BMC microbiology 20100101
Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells. Toxicology and applied pharmacology 20091215
Removal of arsenic from water: effect of calcium ions on As(III) removal in the KMnO(4)-Fe(II) process. Water research 20091201
Arsenicals produce stable progressive changes in DNA methylation patterns that are linked to malignant transformation of immortalized urothelial cells. Toxicology and applied pharmacology 20091201
TDP-43 is recruited to stress granules in conditions of oxidative insult. Journal of neurochemistry 20091101
Tpl2 is a key mediator of arsenite-induced signal transduction. Cancer research 20091015
Arsenite medicinal use, metabolism, pharmacokinetics and monitoring in human hair. Biochimie 20091001
Coordinated regulation of angiopoietin-1 and vascular endothelial growth factor by arsenite in human brain microvascular pericytes: implications of arsenite-induced vascular dysfunction. Toxicology 20091001
Comparative functional genomic analysis identifies distinct and overlapping sets of genes required for resistance to monomethylarsonous acid (MMAIII) and arsenite (AsIII) in yeast. Toxicological sciences : an official journal of the Society of Toxicology 20091001
Increased sensitivity to platinating agents and arsenite in human ovarian cancer by downregulation of ASNA1. Oncology reports 20091001
Removal of arsenite by Fe(VI), Fe(VI)/Fe(III), and Fe(VI)/Al(III) salts: effect of pH and anions. Journal of hazardous materials 20090930
Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase. Toxicology and applied pharmacology 20090901
Differential response of antioxidative defense system of Anabaena doliolum under arsenite and arsenate stress. Journal of basic microbiology 20090901
Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5'-UTR. Gene 20090901
Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging cell 20090901
Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: contribution of NADPH oxidase. Free radical biology & medicine 20090815
Increasing sulfur supply enhances tolerance to arsenic and its accumulation in Hydrilla verticillata (Lf.) Royle. Environmental science & technology 20090815
Aberrant cytokeratin expression during arsenic-induced acquired malignant phenotype in human HaCaT keratinocytes consistent with epidermal carcinogenesis. Toxicology 20090803
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols. Toxicological sciences : an official journal of the Society of Toxicology 20090801
Uptake of arsenite by synthetic layered double hydroxides. Water research 20090801
Properties of arsenite efflux permeases (Acr3) from Alkaliphilus metalliredigens and Corynebacterium glutamicum. The Journal of biological chemistry 20090724
Evidence for toxicity differences between inorganic arsenite and thioarsenicals in human bladder cancer cells. Toxicology and applied pharmacology 20090715
Identification of a splice variant of the metal-responsive transcription factor MTF-1 in common carp. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090701
Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium. Toxicology 20090630
Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes. Free radical biology & medicine 20090615
[Removal of arsenite from drinking water by activated carbon supported nano zero-valent iron]. Huan jing ke xue= Huanjing kexue 20090615
Redox cycling of arsenic by the hydrothermal marine bacterium Marinobacter santoriniensis. Environmental microbiology 20090601
Comparing the relative oxidative DNA damage caused by various arsenic species by quantifying urinary levels of 8-hydroxy-2'-deoxyguanosine with isotope-dilution liquid chromatography/mass spectrometry. Pharmaceutical research 20090601
Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes. Toxicology and applied pharmacology 20090601
Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell. Toxicology letters 20090601
Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium. Toxicology letters 20090601
Proteomics view of a Rhizobium isolate response to arsenite [As(III)] stress. Acta microbiologica et immunologica Hungarica 20090601
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange. The Journal of biological chemistry 20090529
Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle. The Journal of biological chemistry 20090529
New insight into the oxidation of arsenite by the reaction of zerovalent iron and oxygen. Comment on 'pH dependence of Fenton reagent generation and As(III) oxidation and removal by corrosion of zero valent iron in aerated water'. Environmental science & technology 20090515
Rapid responses of a melanophore cell line to chemical contaminants in water. Journal of applied toxicology : JAT 20090501
Impact of arsenic on nucleotide excision repair: XPC function, protein level, and gene expression. Molecular nutrition & food research 20090501
The heat-induced gamma-H2AX response does not play a role in hyperthermic cell killing. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20090501
Comparison of sensitivity to arsenic compounds between a Bhas 42 cell transformation assay and a BALB/c 3T3 cell transformation assay. Mutation research 20090430
Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells. Toxicology and applied pharmacology 20090415
Urinary arsenic methylation capability and carotid atherosclerosis risk in subjects living in arsenicosis-hyperendemic areas in southwestern Taiwan. The Science of the total environment 20090401
Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments. Experimental cell research 20090401
Dynein motor contributes to stress granule dynamics in primary neurons. Neuroscience 20090317
Reaction of the catalytic cysteine of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with arsenite-BAL and phenylarsine oxide. Chemico-biological interactions 20090316
Inhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damage. The Journal of biological chemistry 20090313
Differential response of arsenic stress in two varieties of Brassica juncea L. Chemosphere 20090301
Optimization of preservation conditions of As (III) bioreporter bacteria. Applied microbiology and biotechnology 20090301
c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells. Toxicology and applied pharmacology 20090215
Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation. Toxicology and applied pharmacology 20090215
Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for glutathione synthetase. Toxicological sciences : an official journal of the Society of Toxicology 20090201
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. Experimental cell research 20090201
Arsenite and its mono- and dimethylated trivalent metabolites enhance the formation of benzo[a]pyrene diol epoxide-DNA adducts in Xeroderma pigmentosum complementation group A cells. Chemical research in toxicology 20090201
Arsenite oxidation by immobilized cells of Alcaligenes faecalis strain O1201 in a fluidized-bed reactor. Water environment research : a research publication of the Water Environment Federation 20090201
Arsenic(III) species inhibit oxidative protein folding in vitro. Biochemistry 20090120
Simple and selective determination of arsenite and arsenate by electrospray ionization mass spectrometry. Analytica chimica acta 20090105
Arsenite suppresses Notch1 signaling in human keratinocytes. The Journal of investigative dermatology 20090101
Melatonin inhibits arsenite-induced peripheral neurotoxicity. Journal of pineal research 20090101
Swarming motility: a multicellular behaviour conferring antimicrobial resistance. Environmental microbiology 20090101
A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures. Toxicological sciences : an official journal of the Society of Toxicology 20090101
p53 regulates Hsp90beta during arsenite-induced cytotoxicity in glutathione-deficient cells. Archives of biochemistry and biophysics 20090101
Discovery of the aquaporins and development of the field. Handbook of experimental pharmacology 20090101
Genes involved in arsenic transformation and resistance associated with different levels of arsenic-contaminated soils. BMC microbiology 20090101
Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC genomics 20090101
Expression of AS3MT alters transcriptional profiles in human urothelial cells exposed to arsenite. Human & experimental toxicology 20090101
Investigations of the posttranslational mechanism of arsenite-mediated downregulation of human cytochrome P4501A1 levels: the role of heme oxygenase-1. Journal of biochemical and molecular toxicology 20090101
Comparative biochemical and transcriptional profiling of two contrasting varieties of Brassica juncea L. in response to arsenic exposure reveals mechanisms of stress perception and tolerance. Journal of experimental botany 20090101
Carbon and arsenic metabolism in Thiomonas strains: differences revealed diverse adaptation processes. BMC microbiology 20090101
Aquaglyceroporins are involved in uptake of arsenite into murine gastrointestinal tissues. The journal of medical investigation : JMI 20090101
Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways. Toxicology and applied pharmacology 20081215
Effects of inorganic arsenic on the rat and mouse urinary bladder. Toxicological sciences : an official journal of the Society of Toxicology 20081201
As(III) inhibits ultraviolet radiation-induced cyclobutane pyrimidine dimer repair via generation of nitric oxide in human keratinocytes. Free radical biology & medicine 20081015
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile. Toxicology and applied pharmacology 20081001
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nature cell biology 20081001
Stressed out? Make some modifications! Nature cell biology 20081001
Arsenic-induced aberrant gene expression in fetal mouse primary liver-cell cultures. Annals of the New York Academy of Sciences 20081001
Protective effect of dietary phytochemicals against arsenite induced genotoxicity in mammalian V79 cells. Indian journal of experimental biology 20081001
Arsenite reduces insulin secretion in rat pancreatic beta-cells by decreasing the calcium-dependent calpain-10 proteolysis of SNAP-25. Toxicology and applied pharmacology 20080915
Arsenite alters global histone H3 methylation. Carcinogenesis 20080901
Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2. Free radical biology & medicine 20080901
Comparative toxicity of arsenite metabolites in wild type CHO cells and in cells deficient in excision repair cross-complementing 1 and 2. Toxicology in vitro : an international journal published in association with BIBRA 20080901
Dual actions involved in arsenite-induced oxidative DNA damage. Chemical research in toxicology 20080901
The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies. Toxicology 20080819
BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite. The Journal of biological chemistry 20080815
Identification and characterisation of arsenite (+3 Oxidation State) methyltransferase (AS3MT) in mouse neuroblastoma cell line N1E-115. Amino acids 20080801
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicology and applied pharmacology 20080801
Arsenite and cadmium, but not chromium, induce NAD(P)H:quinone oxidoreductase 1 through transcriptional mechanisms, in spite of post-transcriptional modifications. Toxicology in vitro : an international journal published in association with BIBRA 20080801
Arsenite-induced germline apoptosis through a MAPK-dependent, p53-independent pathway in Caenorhabditis elegans. Chemical research in toxicology 20080801
Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway. Electrophoresis 20080801
Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization. Toxicology and applied pharmacology 20080715
XAS study of arsenic coordination in Euglena gracilis exposed to arsenite. Environmental science & technology 20080715
Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro. Toxicology 20080710
Role of conserved aspartates in the ArsA ATPase. Biochemistry 20080708
Adsorptive removal of As(V) and As(III) from water by a Zr(IV)-loaded orange waste gel. Journal of hazardous materials 20080615
Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite. Toxicology and applied pharmacology 20080501
Occurrence of resistance to antibiotics, UV-B, and arsenic in bacteria isolated from extreme environments in high-altitude (above 4400 m) Andean wetlands. Current microbiology 20080501
[Construction and expression of different mutants of human p53 and their effects on arsenite-induced cell apoptosis]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080501
Arsenite-induced cytotoxicity in dorsal root ganglion explants. Free radical biology & medicine 20080415
Neural differentiation and the attenuated heat shock response. Brain research 20080408
Synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma SH-SY5Y cells. Toxicological sciences : an official journal of the Society of Toxicology 20080401
Positive signaling interactions between arsenic and ethanol for angiogenic gene induction in human microvascular endothelial cells. Toxicological sciences : an official journal of the Society of Toxicology 20080401
Mechanism of arsenic-induced neurotoxicity may be explained through cleavage of p35 to p25 by calpain. Toxicology in vitro : an international journal published in association with BIBRA 20080401
Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts. Free radical research 20080401
Transformation of human urothelial cells (UROtsa) by as and cd induces the expression of keratin 6a. Environmental health perspectives 20080401
Arsenic uptake and speciation in rice plants grown under greenhouse conditions with arsenic contaminated irrigation water. The Science of the total environment 20080325
Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite. Toxicology and applied pharmacology 20080315
High dietary fat exacerbates arsenic-induced liver fibrosis in mice. Experimental biology and medicine (Maywood, N.J.) 20080301
Stress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region. The Journal of biological chemistry 20080201
Divergence of trypanothione-dependent tryparedoxin cascade into cytosolic and mitochondrial pathways in arsenite-resistant variants of Leishmania amazonensis. Molecular and biochemical parasitology 20080201
Regulation of NO from endothelial cells by the decrease of cellular cAMP under arsenite exposure. Journal of microbiology and biotechnology 20080201
Gene expression levels in normal human lymphoblasts with variable sensitivities to arsenite: identification of GGT1 and NFKBIE expression levels as possible biomarkers of susceptibility. Toxicology and applied pharmacology 20080115
Arsenite oxidation by a chemoautotrophic moderately acidophilic Thiomonas sp.: from the strain isolation to the gene study. Environmental microbiology 20080101
Characterization of the metalloactivation domain of an arsenite/antimonite resistance pump. Molecular microbiology 20080101
PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation. Environmental health perspectives 20080101
A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. PloS one 20080101
Selective activation of NF-kappaB and E2F by low concentration of arsenite in U937 human monocytic leukemia cells. Journal of biochemical and molecular toxicology 20080101
A subgroup of plant aquaporins facilitate the bi-directional diffusion of As(OH)3 and Sb(OH)3 across membranes. BMC biology 20080101
Oxidative damage induced genotoxic effects in human fibroblasts from Xeroderma Pigmentosum group A patients. The international journal of biochemistry & cell biology 20080101
The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. Experimental cell research 20071210
Determination of configuration of arsenite-glutathione complexes using ECSTM. Toxicology letters 20071210
Quantitative GFP fluorescence as an indicator of arsenite developmental toxicity in mosaic heat shock protein 70 transgenic zebrafish. Toxicology and applied pharmacology 20071201
Arsenite-enhanced procoagulant activity through phosphatidylserine exposure in platelets. Chemical research in toxicology 20071201
ArsD: an As(III) metallochaperone for the ArsAB As(III)-translocating ATPase. Journal of bioenergetics and biomembranes 20071201
N-acetylcysteine attenuates arsenite-induced oxidative injury in dorsal root ganglion explants. Annals of the New York Academy of Sciences 20071201
Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors. Toxicological sciences : an official journal of the Society of Toxicology 20071101
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis. Toxicological sciences : an official journal of the Society of Toxicology 20071101
Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite. Environmental and molecular mutagenesis 20071001
Impact of arsenic in foodstuffs on the people living in the arsenic-affected areas of West Bengal, India. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20071001
Arsenite induced oxidative damage in mouse liver is associated with increased cytokeratin 18 expression. Archives of toxicology 20070901
Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein. Journal of pineal research 20070901
Induction of apoptosis-like cell death by pentamidine and doxorubicin through differential inhibition of topoisomerase II in arsenite-resistant L. donovani. Acta tropica 20070901
Preconcentration of trace arsenite and arsenate with titanium dioxide nanoparticles and subsequent determination by silver diethyldithiocarbamate spectrophotometric method. Water environment research : a research publication of the Water Environment Federation 20070901
Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation. The Journal of biological chemistry 20070803
Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite. Journal of cellular physiology 20070801
Arsenite-induced apoptosis is prevented by antioxidants in zebrafish liver cell line. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Protective effects of hepatocellular canalicular conjugate export pump (Mrp2) on sodium arsenite-induced hepatic dysfunction in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070801
Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium. Toxicology letters 20070801
Tim18, a component of the mitochondrial translocator, mediates yeast cell death induced by arsenic. Biochemistry. Biokhimiia 20070801
A critical role for IkappaB kinase beta in metallothionein-1 expression and protection against arsenic toxicity. The Journal of biological chemistry 20070720
PI-3K/Akt signal pathway plays a crucial role in arsenite-induced cell proliferation of human keratinocytes through induction of cyclin D1. Journal of cellular biochemistry 20070701
Incorporation of an internal ribosome entry site-dependent mechanism in arsenic-induced GADD45 alpha expression. Cancer research 20070701
A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn. Journal of clinical biochemistry and nutrition 20070701
Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite. Physiological genomics 20070619
Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicity. Toxicology in vitro : an international journal published in association with BIBRA 20070601
Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential. Toxicology and applied pharmacology 20070515
Direct evidence of arsenic(III)-carbonate complexes obtained using electrochemical scanning tunneling microscopy. Analytical chemistry 20070515
Probing the mRNA processing body using protein macroarrays and 'autoantigenomics'. RNA (New York, N.Y.) 20070501
Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid. Environmental health perspectives 20070501
Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells. Environmental health perspectives 20070401
The arsenite oxidase genes (aroAB) in novel chemoautotrophic arsenite oxidizers. Biochemical and biophysical research communications 20070316
Alkalilimnicola ehrlichii sp. nov., a novel, arsenite-oxidizing haloalkaliphilic gammaproteobacterium capable of chemoautotrophic or heterotrophic growth with nitrate or oxygen as the electron acceptor. International journal of systematic and evolutionary microbiology 20070301
Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions. Environmental health perspectives 20070301
Cell stress modulates the function of splicing regulatory protein RBM4 in translation control. Proceedings of the National Academy of Sciences of the United States of America 20070213
The bile/arsenite/riboflavin transporter (BART) superfamily. The FEBS journal 20070201
Glutathione protects cells against arsenite-induced toxicity. Free radical biology & medicine 20070115
Contributions of reactive oxygen species and mitogen-activated protein kinase signaling in arsenite-stimulated hemeoxygenase-1 production. Toxicology and applied pharmacology 20070115
Regulation of the arsenic-responsive transcription factor Yap8p involves the ubiquitin-proteasome pathway. Journal of cell science 20070115
Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and biophysical research communications 20070105
Impact of arsenite and its methylated metabolites on PARP-1 activity, PARP-1 gene expression and poly(ADP-ribosyl)ation in cultured human cells. DNA repair 20070104
Lysosomes and trivalent arsenic treatment in acute promyelocytic leukemia. Journal of the National Cancer Institute 20070103
Effects of combined administration of captopril and DMSA on arsenite induced oxidative stress and blood and tissue arsenic concentration in rats. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101
Oxidation of aqueous EDTA and associated organics and coprecipitation of inorganics by ambient iron-mediated aeration. Environmental science & technology 20070101
Determination of inorganic arsenic(III) and arsenic(V) in water samples by ion chromatography/inductively coupled plasma-mass spectrometry. Journal of AOAC International 20070101
Rapid reduction of arsenate in the medium mediated by plant roots. The New phytologist 20070101
The steroidogenic acute regulatory protein as a target of endocrine disruption in male reproduction. Drug metabolism reviews 20070101
Effect of proteasome inhibition on toxicity and CYP3A23 induction in cultured rat hepatocytes: comparison with arsenite. Toxicology and applied pharmacology 20061215
Urothelial cells malignantly transformed by exposure to cadmium (Cd(+2)) and arsenite (As(+3)) have increased resistance to Cd(+2) and As(+3)-induced cell death. Toxicological sciences : an official journal of the Society of Toxicology 20061201
Elevation of cellular BPDE uptake by human cells: a possible factor contributing to co-carcinogenicity by arsenite. Environmental health perspectives 20061201
Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture. Toxicology and applied pharmacology 20061115
Photocatalytic oxidation of arsenite on TiO2: understanding the controversial oxidation mechanism involving superoxides and the effect of alternative electron acceptors. Environmental science & technology 20061115
Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses. The Journal of biological chemistry 20061110
Whole-cell arsenite biosensor using photosynthetic bacterium Rhodovulum sulfidophilum. Rhodovulum sulfidophilum as an arsenite biosensor. Applied microbiology and biotechnology 20061101
Arsenite inhibits p53 phosphorylation, DNA binding activity, and p53 target gene p21 expression in mouse epidermal JB6 cells. Molecular carcinogenesis 20061101
Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells. Toxicology and applied pharmacology 20061101
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration. Toxicology and applied pharmacology 20061101
Arsenite modulates cardiac substrate preference by translocation of GLUT4, but not CD36, independent of mitogen-activated protein kinase signaling. Endocrinology 20061101
Assessment of stress-related gene expression in the heavy metal-exposed nematode Caenorhabditis elegans: a potential biomarker for metal-induced toxicity monitoring and environmental risk assessment. Environmental toxicology and chemistry 20061101
The antioxidant role of a reagent, 2',7'-dichlorodihydrofluorescin diacetate, detecting reactive-oxygen species and blocking the induction of heme oxygenase-1 and preventing cytotoxicity. Journal of biochemistry 20061001
An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Molecular cell 20060915
Involvement of hydrogen peroxide in the differentiation and apoptosis of preosteoclastic cells exposed to arsenite. Biochemical pharmacology 20060914
Arsenite induces apoptosis in hepatocytes through an enhancement of the activation of Jun N-terminal kinase and p38 mitogen-activated protein kinase caused by partial hepatectomy. Toxicology letters 20060910
Exit from arsenite-induced mitotic arrest is p53 dependent. Environmental health perspectives 20060901
Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells. The Journal of biological chemistry 20060825
Coprecipitation of arsenate with metal oxides: nature, mineralogy, and reactivity of aluminum precipitates. Environmental science & technology 20060815
Arsenite pretreatment enhances the cytotoxicity of mitomycin C in human cancer cell lines via increased NAD(P)H quinone oxidoreductase 1 expression. Toxicology and applied pharmacology 20060801
Herminiimonas arsenicoxydans sp. nov., a metalloresistant bacterium. International journal of systematic and evolutionary microbiology 20060801
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells. Journal of biomedical science 20060701
p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1. The Journal of pharmacology and experimental therapeutics 20060701
Arsenic-resistant proteobacterium from the phyllosphere of arsenic-hyperaccumulating fern (Pteris vittata L.) reduces arsenate to arsenite. Canadian journal of microbiology 20060701
Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance. Oncogene 20060622
A keratin 18 transgenic zebrafish Tg(k18(2.9):RFP) treated with inorganic arsenite reveals visible overproliferation of epithelial cells. Toxicology letters 20060601
Extraction of arsenate and arsenite species from soils and sediments. Environmental pollution (Barking, Essex : 1987) 20060501
Dynamic regulation and involvement of the heat shock transcriptional response in arsenic carcinogenesis. Journal of cellular physiology 20060501
Anaerobic biotransformation of roxarsone and related N-substituted phenylarsonic acids. Environmental science & technology 20060501
Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells. Carcinogenesis 20060401
Dithiol compounds at low concentrations increase arsenite toxicity. Toxicological sciences : an official journal of the Society of Toxicology 20060401
Single and combination toxic metal exposures induce apoptosis in cultured murine podocytes exclusively via the extrinsic caspase 8 pathway. Toxicological sciences : an official journal of the Society of Toxicology 20060401
Arsenite induces aberrations in meiosis that can be prevented by coadministration of N-acetylcysteine in mice. Fertility and sterility 20060401
Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes. Biology of reproduction 20060301
Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolites. Environmental health perspectives 20060301
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060301
Predicting metals sensed by ArsR-SmtB repressors: allosteric interference by a non-effector metal. Molecular microbiology 20060201
Altered iron homeostasis involvement in arsenite-mediated cell transformation. Free radical biology & medicine 20060201
Evaluation of immunotoxic and immunodisruptive effects of inorganic arsenite on human monocytes/macrophages. International immunopharmacology 20060201
Aerial oxidation of the glucocorticoid side-chain under pH control. Steroids 20060101
Electrochemical and XAFS studies of effects of carbonate on the oxidation of arsenite. Environmental science & technology 20060101
Anion adsorption on oxide surfaces: inclusion of the water dipole in modeling the electrostatics of ligand exchange. Environmental science & technology 20060101
D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC cell biology 20060101
Arsenite binding to synthetic peptides: the effect of increasing length between two cysteines. Journal of biochemical and molecular toxicology 20060101
Dissociation of arsenite-peptide complexes: triphasic nature, rate constants, half-lives, and biological importance. Journal of biochemical and molecular toxicology 20060101
Chemical extraction of arsenic from contaminated soil. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20060101
Arsenite increases vasoconstrictor reactivity in rat blood vessels: role of endothelial nitric oxide function. International journal of toxicology 20060101
Influence of antimonite, selenite, and mercury on the toxicity of arsenite in primary rat hepatocytes. Biological trace element research 20060101
Combined efficacies of DL-alpha-lipoic acid and meso 2,3 dimercaptosuccinic acid against arsenic induced toxicity in antioxidant systems of rats. Toxicology letters 20051230
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite. Free radical biology & medicine 20051215
Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms. Toxicology and applied pharmacology 20051201
Uptake, translocation and transformation of arsenate and arsenite in sunflower (Helianthus annuus): formation of arsenic-phytochelatin complexes during exposure to high arsenic concentrations. The New phytologist 20051201
Lack of poly(ADP-ribose) polymerase-1 gene product enhances cellular sensitivity to arsenite. Cancer research 20051201
Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein. The Biochemical journal 20051115
Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1. Toxicology and applied pharmacology 20051115
Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells. Toxicology letters 20051015
Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha. The Journal of biological chemistry 20051007
Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status. Toxicological sciences : an official journal of the Society of Toxicology 20051001
Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite. Molecular and cellular biology 20051001
Inorganic arsenite potentiates vasoconstriction through calcium sensitization in vascular smooth muscle. Environmental health perspectives 20051001
Caenorhabditis elegans gcs-1 confers resistance to arsenic-induced oxidative stress. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20051001
Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells. Toxicology 20050915
Arsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk? Toxicology and applied pharmacology 20050901
Heat shock protein 70 as an indicator of early lung injury caused by exposure to arsenic. Molecular and cellular biochemistry 20050901
Arsenite maintains germinative state in cultured human epidermal cells. Toxicology and applied pharmacology 20050822
Mechanism of arsenite-mediated decreases in CYP3A23 in rat hepatocytes. Biochemical and biophysical research communications 20050812
Trapping of arsenite by mercaptopropyl-functionalized mesostructured silica with a wormhole framework. Chemical communications (Cambridge, England) 20050807
Distinct IkappaB kinase regulation in adult T cell leukemia and HTLV-I-transformed cells. Experimental cell research 20050801
Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes. Molecular pharmacology 20050801
Arsenite binding to synthetic peptides based on the Zn finger region and the estrogen binding region of the human estrogen receptor-alpha. Toxicology and applied pharmacology 20050801
Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryotic cell 20050801
Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals 20050701
Distinct overexpression of cytosolic and mitochondrial tryparedoxin peroxidases results in preferential detoxification of different oxidants in arsenite-resistant Leishmania amazonensis with and without DNA amplification. Molecular and biochemical parasitology 20050701
Proteome analysis of maize roots reveals that oxidative stress is a main contributing factor to plant arsenic toxicity. Phytochemistry 20050701
Human epidermal cell protein responses to arsenite treatment in culture. Chemico-biological interactions 20050630
Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function. Journal of immunology (Baltimore, Md. : 1950) 20050615
Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2. Journal of cellular physiology 20050601
Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis. Toxicological sciences : an official journal of the Society of Toxicology 20050601
The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism. The Journal of biological chemistry 20050527
A microbial arsenic cycle in a salt-saturated, extreme environment. Science (New York, N.Y.) 20050527
Involvement of protein kinase PKN1 in G2/M delay caused by arsenite. Molecular carcinogenesis 20050501
Novobiocin induces apoptosis-like cell death in topoisomerase II over-expressing arsenite resistant Leishmania donovani. Molecular and biochemical parasitology 20050501
Bacillus arsenicus sp. nov., an arsenic-resistant bacterium isolated from a siderite concretion in West Bengal, India. International journal of systematic and evolutionary microbiology 20050501
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. The Journal of biological chemistry 20050429
Thermodynamics of the As(III)-thiol interaction: arsenite and monomethylarsenite complexes with glutathione, dihydrolipoic acid, and other thiol ligands. Inorganic chemistry 20050418
A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19. Archives of toxicology 20050401
Arsenite inhibition of CYP1A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cell cycle arrest. Molecular pharmacology 20050401
High-level arsenite removal from groundwater by zero-valent iron. Chemosphere 20050401
Combined effects of gamma radiation and arsenite on the proteome of human TK6 lymphoblastoid cells. Mutation research 20050307
Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells. Drug metabolism and disposition: the biological fate of chemicals 20050301
Differential induction of podocyte heat shock proteins by prolonged single and combination toxic metal exposure. Toxicological sciences : an official journal of the Society of Toxicology 20050301
The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1. The international journal of biochemistry & cell biology 20050301
Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated steroidogenic acute regulatory (StAR) protein. Molecular and cellular endocrinology 20050227
A comparison of hepatocyte cytotoxic mechanisms for chromate and arsenite. Toxicology 20050131
Arsenite induces prominent mitotic arrest via inhibition of G2 checkpoint activation in CGL-2 cells. Carcinogenesis 20050101
Dead or dying: the importance of time in cytotoxicity assays using arsenite as an example. Toxicology and applied pharmacology 20050101
An automated system for measuring parameters of nematode sinusoidal movement. BMC genetics 20050101
Neovascularization and angiogenic gene expression following chronic arsenic exposure in mice. Cardiovascular toxicology 20050101
Arsenite regulates Cystic Fibrosis Transmembrane Conductance Regulator and P-glycoprotein: evidence of pathway independence. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
Evaluation of immunotoxic and immunodisruptive effects of inorganic arsenite on human monocytes/macrophages. International immunopharmacology 20041215
The role of thiol species in the hypertolerance of Aspergillus sp. P37 to arsenic. The Journal of biological chemistry 20041203
Oxidative activation of the human carcinogen chromate by arsenite: a model for synergistic metal activation leading to oxidative DNA damage. Toxicology in vitro : an international journal published in association with BIBRA 20041201
Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice. Environmental health perspectives 20041201
Low-level arsenite activates the transcription of genes involved in adipose differentiation. Cell biology and toxicology 20041101
A proteome analysis of the arsenite response in cultured lung cells: evidence for in vitro oxidative stress-induced apoptosis. The Biochemical journal 20040901
Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes. Toxicology and applied pharmacology 20040801
The zinc finger transcription factor Egr-1 is upregulated in arsenite-treated human keratinocytes. Journal of molecular medicine (Berlin, Germany) 20040801
Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chemical research in toxicology 20040801
Biokinetics and subchronic toxic effects of oral arsenite, arsenate, monomethylarsonic acid, and dimethylarsinic acid in v-Ha-ras transgenic (Tg.AC) mice. Environmental health perspectives 20040801
Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required. The Journal of biological chemistry 20040730
Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes. Molecular endocrinology (Baltimore, Md.) 20040701
Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals. Chemical research in toxicology 20040701
Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway. The Journal of biological chemistry 20040521
p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. The Journal of biological chemistry 20040521
Preservation of As(III) and As(V) in drinking water supply samples from across the United States using EDTA and acetic acid as a means of minimizing iron-arsenic coprecipitation. Environmental science & technology 20040515
Effects of TiO2 surface modifications on photocatalytic oxidation of arsenite: the role of superoxides. Environmental science & technology 20040515
Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. The Journal of biological chemistry 20040507
Experimental and theoretical characterization of arsenite in water: insights into the coordination environment of As-O. Inorganic chemistry 20040503
Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell. Journal of applied physiology (Bethesda, Md. : 1985) 20040501
Arsenic inhibition of the JAK-STAT pathway. Oncogene 20040429
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. The EMBO journal 20040324
Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells. Blood 20040301
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA. Biomedical and environmental sciences : BES 20040301
Respiration-dependent removal of exogenous H2O2 in brain mitochondria: inhibition by Ca2+. The Journal of biological chemistry 20040206
The protective role of intracellular GSH status in the arsenite-induced vascular endothelial dysfunction. Chemical research in toxicology 20040201
Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells. Carcinogenesis 20040101
Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment. Chemical research in toxicology 20040101
Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells. Molecular and cellular biochemistry 20040101
Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells. Molecular and cellular biochemistry 20040101
Nitric oxide production by arsenite. Mutation research 20031210
Arsenite and its biomethylated metabolites interfere with the formation and repair of stable BPDE-induced DNA adducts in human cells and impair XPAzf and Fpg. DNA repair 20031209
Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. The British journal of dermatology 20031201
Mercury, cadmium, and arsenite enhance heat shock protein synthesis in chick embryos prior to embryotoxicity. Birth defects research. Part B, Developmental and reproductive toxicology 20031201
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology letters 20031130
Oxidation and detoxification of trivalent arsenic species. Toxicology and applied pharmacology 20031115
Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase. Experimental cell research 20031015
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity. European journal of biochemistry 20031001
Induction of structural and numerical changes of chromosome, centrosome abnormality, multipolar spindles and multipolar division in cultured Chinese hamster V79 cells by exposure to a trivalent dimethylarsenic compound. Mutation research 20030929
Active arsenic species produced by GSH-dependent reduction of dimethylarsinic acid cause micronuclei formation in peripheral reticulocytes of mice. Mutation research 20030805
Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38. Cellular signalling 20030801
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans. Environmental health perspectives 20030801
Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochemical and biophysical research communications 20030530
Metalloid tolerance based on phytochelatins is not functionally equivalent to the arsenite transporter Acr3p. Biochemical and biophysical research communications 20030502
Blockade of calcium entry accelerates arsenite-mediated apoptosis in rat cerebellar granule cells. Molecules and cells 20030430
Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. The Journal of biological chemistry 20030411
Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity. Molecular and cellular biology 20030401
Arsenic-induced dysfunction in relaxation of blood vessels. Environmental health perspectives 20030401
Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF. Oncogene 20030327
Arsenite-induced phosphorylation of histone H3 at serine 10 is mediated by Akt1, extracellular signal-regulated kinase 2, and p90 ribosomal S6 kinase 2 but not mitogen- and stress-activated protein kinase 1. The Journal of biological chemistry 20030321
The RasGAP-associated endoribonuclease G3BP assembles stress granules. The Journal of cell biology 20030317
Stress-induced gene expression requires programmed recovery from translational repression. The EMBO journal 20030303
Cross-linking of surface IgM in the Burkitt's lymphoma cell line ST486 provides protection against arsenite- and stress-induced apoptosis that is mediated by ERK and phosphoinositide 3-kinase signaling pathways. The Journal of biological chemistry 20030207
Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells. American journal of physiology. Gastrointestinal and liver physiology 20030201
Dose-dependent biotransformation of arsenite in rats--not S-adenosylmethionine depletion impairs arsenic methylation at high dose. Toxicology 20030201
Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicology and applied pharmacology 20030115
Proteomic analyses of arsenic-induced cell transformation with SELDI-TOF ProteinChip technology. Journal of cellular biochemistry 20030101
Arsenite induces delayed mutagenesis and transformation in human osteosarcoma cells at extremely low concentrations. Environmental and molecular mutagenesis 20030101
Inorganic arsenite-induced malignant transformation of human prostate epithelial cells. Journal of the National Cancer Institute 20021218
Reduction of arsenate to arsenite in hepatic cytosol. Toxicological sciences : an official journal of the Society of Toxicology 20021101
Purine nucleoside phosphorylase as a cytosolic arsenate reductase. Toxicological sciences : an official journal of the Society of Toxicology 20021101
Coordination of altered DNA repair and damage pathways in arsenite-exposed keratinocytes. Toxicological sciences : an official journal of the Society of Toxicology 20021001
Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite. Environmental health perspectives 20021001
Quantitative trace-level speciation of arsenite and arsenate in drinking water by ion chromatography. The Analyst 20021001
Phosphorylation of tyrosine hydroxylase in isolated mice adrenal glands. Annals of the New York Academy of Sciences 20021001
Involvement of reactive oxygen species in arsenite-induced downregulation of phospholipid hydroperoxide glutathione peroxidase in human epidermoid carcinoma A431 cells. Free radical biology & medicine 20020915
Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite. Archives of biochemistry and biophysics 20020915
Photocatalytic oxidation of arsenite in TiO2 suspension: kinetics and mechanisms. Environmental science & technology 20020901
Expression of hsp 90 in the human kidney and in proximal tubule cells exposed to heat, sodium arsenite and cadmium chloride. Toxicology letters 20020721
Arsenite-induced reactive oxygen species and the repression of alpha-tocopherol in the MGC-803 cells. European journal of pharmacology 20020712
Differential activation of the c-Jun N-terminal kinase pathway in arsenite-induced apoptosis and sensitization of chemically resistant compared to susceptible B-lymphoma cell lines. Toxicological sciences : an official journal of the Society of Toxicology 20020701
Differential activation of ERK and JNK by arsenite in mouse muscle cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020701
Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors. European journal of biochemistry 20020601
Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. Mutation research 20020527
A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis. Chemical research in toxicology 20020501
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proceedings of the National Academy of Sciences of the United States of America 20020430
Differential effects of stress stimuli on a JNK-inactivating phosphatase. Oncogene 20020404
Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression. Toxicology 20020227
Low-level self-tolerance to arsenite in human HepG2 cells is associated with a depressed induction of micronuclei. Mutation research 20020215
Arsenite pretreatment attenuates benzo[a]pyrene cytotoxicity in a human lung adenocarcinoma cell line by decreasing cyclooxygenase-2 levels. Journal of toxicology and environmental health. Part A 20020201
Glucocorticoid-induced glucose release is abolished in trout hepatocytes with elevated hsp70 content. The Journal of endocrinology 20020101
Arsenite stabilizes IkappaBalpha and prevents NF-kappaB activation in IL-1 beta-stimulated Caco-2 cells independent of the heat shock response. Journal of cellular biochemistry 20020101
Arsenite stimulates cyclooxygenase-2 expression through activating IkappaB kinase and nuclear factor kappaB in primary and ECV304 endothelial cells. Journal of cellular biochemistry 20020101
Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020101
Decrease of fibrinolytic activity in human endothelial cells by arsenite. Thrombosis research 20020101
Arsenic induces oxidative DNA damage in mammalian cells. Molecular and cellular biochemistry 20020101
Arsenic induces oxidative stress and activates stress gene expressions in cultured lung epithelial cells. Journal of cellular biochemistry 20020101
Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. The Journal of biological chemistry 20011221
Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicology and applied pharmacology 20011215
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. Molecular and cellular biology 20011201
Structure-function analysis of the ArsA ATPase: contribution of histidine residues. Journal of bioenergetics and biomembranes 20011201
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437. Oncogene 20011115
Arsenate and arsenite removal by zerovalent iron: effects of phosphate, silicate, carbonate, borate, sulfate, chromate, molybdate, and nitrate, relative to chloride. Environmental science & technology 20011115
Arsenite oxidation and arsenate respiration by a new Thermus isolate. FEMS microbiology letters 20011113
Arsenite activation of P13K/AKT cell survival pathway is mediated by p38 in cultured human keratinocytes. Molecular medicine (Cambridge, Mass.) 20011101
Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells. Journal of toxicology and environmental health. Part A 20011026
Role of MRP2 and GSH in intrahepatic cycling of toxins. Toxicology 20011005
Effect of phosphate transporter and methylation inhibitor drugs on the disposition of arsenate and arsenite in rats. Toxicological sciences : an official journal of the Society of Toxicology 20010901
Suppression of Fas ligand expression on endothelial cells by arsenite through reactive oxygen species. Toxicology letters 20010806
Arsenite-induced multiple antibiotic resistance phenotype in environmental isolates of Yersinia enterocolitica. Current microbiology 20010801
Keratinocyte differentiation marker suppression by arsenic: mediation by AP1 response elements and antagonism by tetradecanoylphorbol acetate. Toxicology and applied pharmacology 20010801
Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylation-sensitive arbitrarily-primed PCR. Toxicology letters 20010706
Monomethylarsonous acid (MMA(III)) and arsenite: LD(50) in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chemical research in toxicology 20010601
The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae. Molecular microbiology 20010601
Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes. Toxicology and applied pharmacology 20010501
Effect of arsenite on certain aspects of protein metabolism in fresh water teleost, Tilapia mossambica (Peters). Journal of environmental biology 20010401
Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells. American journal of physiology. Lung cellular and molecular physiology 20010301
Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells. European journal of cell biology 20010301
Arsenic alters the function of the glucocorticoid receptor as a transcription factor. Environmental health perspectives 20010301
Effect of metals on polycyclic aromatic hydrocarbon induction of CYP1A1 and CYP1A2 in human hepatocyte cultures. Toxicology and applied pharmacology 20010115
Arsenite inhibits Ras-dependent activation of ERK but activates ERK in the presence of oncogenic Ras in baboon vascular smooth muscle cells. Molecular and cellular biochemistry 20010101
Effect of prostaglandin A1, arsenite and aspirin on stress proteins response in mosquito cells. Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
Contrasting effects of midazolam on induction of heat shock protein 27 by vasopressin and heat in aortic smooth muscle cells. Journal of cellular biochemistry 20010101
Inhibition of arsenite-induced apoptosis by aspirin. Anticancer research 20010101
Functional analysis of a chromosomal arsenic resistance operon in Pseudomonas fluorescens strain MSP3. Molecular biology reports 20010101
Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase. The Journal of biological chemistry 20001117
Effect of arsenite on the induction of CYP1A4 and CYP1A5 in cultured chick embryo hepatocytes. Toxicology and applied pharmacology 20001101
Sensitivity of myelomonocytic leukemia cells to arsenite-induced cell cycle disruption, apoptosis, and enhanced differentiation is dependent on the inter-relationship between arsenic concentration, duration of treatment, and cell cycle phase. The Journal of pharmacology and experimental therapeutics 20001101
Effects of arsenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells. Endocrinology 20001001
Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation. Archives of biochemistry and biophysics 20000501
NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells. Circulation research 20000317
Inhibition of heat shock factor activity prevents heat shock potentiation of glucocorticoid receptor-mediated gene expression. Cell stress & chaperones 19991201
Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein. The Biochemical journal 19990915
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. The Journal of biological chemistry 19990910
Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCl2. Environmental health perspectives 19990701
Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices. Toxicological sciences : an official journal of the Society of Toxicology 19990701
Effect of arsenite on induction of CYP1A, CYP2B, and CYP3A in primary cultures of rat hepatocytes. Toxicology and applied pharmacology 19990515
Arsenic binding proteins from human lymphoblastoid cells. Toxicology letters 19990329
Expression cloning for arsenite-resistance resulted in isolation of tumor-suppressor fau cDNA: possible involvement of the ubiquitin system in arsenic carcinogenesis. Carcinogenesis 19990201
Overexpression of the multidrug resistance-associated protein (MRP1) in human heavy metal-selected tumor cells. FEBS letters 19990129
An integrated pharmacokinetic and pharmacodynamic study of arsenite action. 1. Heme oxygenase induction in rats. Teratogenesis, carcinogenesis, and mutagenesis 19990101
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis. Journal of cellular physiology 19981101
Different populations of progesterone receptor-steroid complexes in binding to specific DNA sequences: effects of salts on kinetics and specificity. The Journal of steroid biochemistry and molecular biology 19981101
Effect of glutathione depletion and metallothionein gene expression on arsenic-induced cytotoxicity and c-myc expression in vitro. Toxicological sciences : an official journal of the Society of Toxicology 19981001
Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. The Journal of biological chemistry 19980918
Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Molecular and cellular biology 19980901
Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo. Cell stress & chaperones 19980901
Biochemical characterization of the human arsenite-stimulated ATPase (hASNA-I). The Journal of biological chemistry 19980828
The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways. The Journal of biological chemistry 19980417
Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms. Chemical research in toxicology 19980401
Induction of the DNA-binding and transcriptional activities of heat shock factor 1 is uncoupled in Xenopus oocytes. Biochimica et biophysica acta 19980312
The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway. The Journal of biological chemistry 19980123
Glutathione peroxidase and catalase modulate the genotoxicity of arsenite. Toxicology 19970905
Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells. European journal of biochemistry 19970801
Involvement of calcium-dependent protein kinase C in arsenite-induced genotoxicity in Chinese hamster ovary cells. Journal of cellular biochemistry 19970301
Prostaglandins stimulate the stress-induced synthesis of hsp27 and alpha B crystallin. Journal of cellular physiology 19970301
Heat shock response inhibits cytokine-inducible nitric oxide synthase expression in rat hepatocytes. Hepatology (Baltimore, Md.) 19961101
Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells. Journal of neurochemistry 19960301
Enhancement of stress-induced synthesis of hsp27 and alpha B crystallin by modulators of the arachidonic acid cascade. Journal of cellular physiology 19960201
Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. Chemical research in toxicology 19951201
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer research 19941115
Coinduction of two low-molecular-weight stress proteins, alpha B crystallin and HSP28, by heat or arsenite stress in human glioma cells. Journal of biochemistry 19931101
Arsenic induces and enhances rat hepatic metallothionein production in vivo. Chemico-biological interactions 19921201
Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors. The Journal of biological chemistry 19920605
Arsenite and cadmium(II) as probes of glucocorticoid receptor structure and function. The Journal of biological chemistry 19900205
Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. The Journal of biological chemistry 19900105
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Inhibition of coupling factor B activity by cadmium ion, arsenite-2,3-dimercaptopropanol, and phenylarsine oxide, and preferential reactivation by dithiols. The Journal of biological chemistry 19811110
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