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Home > Fluorides > 150586-58-6
150586-58-6 | 1H-Imidazole, 5-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-
CAS No: 150586-58-6 Catalog No: AG001MQR MDL No:
Product Description
Catalog Number:
AG001MQR
Chemical Name:
1H-Imidazole, 5-(2-ethyl-5-fluoro-2,3-dihydro-1H-inden-2-yl)-
CAS Number:
150586-58-6
Molecular Formula:
C14H15FN2
Molecular Weight:
230.2807
IUPAC Name:
5-(2-ethyl-5-fluoro-1,3-dihydroinden-2-yl)-1H-imidazole
InChI:
InChI=1S/C14H15FN2/c1-2-14(13-8-16-9-17-13)6-10-3-4-12(15)5-11(10)7-14/h3-5,8-9H,2,6-7H2,1H3,(H,16,17)
InChI Key:
KXSUAWAUCNFBQJ-UHFFFAOYSA-N
SMILES:
CCC1(Cc2c(C1)ccc(c2)F)c1cnc[nH]1
Properties
Complexity:
283
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
230.122g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
230.286g/mol
Monoisotopic Mass:
230.122g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
28.7A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
XLogP3:
3.1
Literature
| Title | Journal |
|---|---|
| Randomized clinical trial of fipamezole for dyskinesia in Parkinson disease (FJORD study). | Neurology 20120710 |
| The α₂ adrenergic antagonist fipamezole improves quality of levodopa action in Parkinsonian primates. | Movement disorders : official journal of the Movement Disorder Society 20101015 |
| Rigid analogues of the α2-adrenergic blocker atipamezole: small changes, big consequences. | Journal of medicinal chemistry 20101014 |
| Santhera licenses novel dyskinesia therapy to Biovail. | Nature reviews. Drug discovery 20091001 |
| Fipamezole (JP-1730) is a potent alpha2 adrenergic receptor antagonist that reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20030801 |
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