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Home > Fluorides > 149301-79-1
CAS No: 149301-79-1 Catalog No: AG001LK2 MDL No:MFCD00236427
Title | Journal |
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Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11. | Oncotarget 20150520 |
Inhibition of cytosolic phospholipase A(2) alpha protects against focal ischemic brain damage in mice. | Brain research 20120830 |
Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney. | Sheng li xue bao : [Acta physiologica Sinica] 20120825 |
Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin. | European journal of pharmacology 20120415 |
Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney. | Biochimica et biophysica acta 20120201 |
Arachidonyl trifluoromethyl ketone ameliorates experimental autoimmune encephalomyelitis via blocking peroxynitrite formation in mouse spinal cord white matter. | Experimental neurology 20110901 |
Cytosolic phospholipase A2 as a molecular target for the radiosensitization of ovarian cancer. | Cancer letters 20110528 |
Stimulation of A(₂a) adenosine receptor abolishes the inhibitory effect of arachidonic acid on the basolateral 50-pS K channel in the thick ascending limb. | American journal of physiology. Renal physiology 20110401 |
Structure-activity relationship studies on 1-(5-carboxyindol-1-yl)-propan-2-one inhibitors of human cytosolic phospholipase A2α: variation of the activated ketone moiety. | Bioorganic & medicinal chemistry letters 20110315 |
Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells. | Journal of cellular biochemistry 20110301 |
COX-2 inhibition and inhibition of cytosolic phospholipase A2 increase CD36 expression and foam cell formation in THP-1 cells. | Lipids 20110201 |
Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells. | Experimental physiology 20100801 |
TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A(2)alpha/cyclooxygenase-2. | Journal of cellular physiology 20100501 |
Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain. | The Journal of pharmacology and experimental therapeutics 20100501 |
Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection. | Journal of neurochemistry 20100301 |
1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase. | Bioorganic & medicinal chemistry 20100115 |
Cytosolic phospholipase A2alpha mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice. | Respiratory research 20100101 |
Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. | Journal of pharmacological sciences 20100101 |
Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. | Journal of medicinal chemistry 20091210 |
Group IVA phospholipase A(2) activity may mediate prostaglandin F(2alpha)-induced luteal regression in pseudopregnant rats. | Prostaglandins & other lipid mediators 20091201 |
Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors. | Journal of medicinal chemistry 20091126 |
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite. | Glia 20091115 |
Arachidonyl trifluoromethyl ketone is neuroprotective after spinal cord injury. | Journal of neurotrauma 20090801 |
Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages. | Chemosphere 20090301 |
Cytosolic phospholipase A2: targeting cancer through the tumor vasculature. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. | Biochemistry 20081230 |
Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages. | Archives of biochemistry and biophysics 20081215 |
Ca2+-independent PLA2 controls endothelial store-operated Ca2+ entry and vascular tone in intact aorta. | American journal of physiology. Heart and circulatory physiology 20081201 |
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain. | Journal of neurochemistry 20081201 |
Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone. | British journal of pharmacology 20081101 |
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. | Nature neuroscience 20081101 |
Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). | The Journal of biological chemistry 20080912 |
[Suppression of cell proliferation by inhibitors to redox signaling in human lens epithelial cells]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20080701 |
Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure. | Cardiovascular research 20080601 |
Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation. | American journal of physiology. Cell physiology 20080601 |
Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries. | American journal of physiology. Heart and circulatory physiology 20080501 |
Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs. | Journal of applied physiology (Bethesda, Md. : 1985) 20080201 |
Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells. | Cell biochemistry and function 20080101 |
Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors. | Developmental neurobiology 20080101 |
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells. | American journal of physiology. Gastrointestinal and liver physiology 20080101 |
Involvement of cPLA2 inhibition in dexamethasone-induced thymocyte apoptosis. | International journal of immunopathology and pharmacology 20080101 |
Role of phospholipase A2 (group I secreted) in the genesis of basal tone in the internal anal sphincter smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20071101 |
Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion. | Cellular and molecular life sciences : CMLS 20071101 |
A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells. | The Journal of biological chemistry 20070713 |
Apoptosis is mediated by cytosolic phospholipase A2 during simulated ischaemia/reperfusion-induced injury in neonatal cardiac myocytes. | Prostaglandins, leukotrienes, and essential fatty acids 20070701 |
Regulation of luteal prostaglandin F(2 alpha) production and its relevance to cell death: an in vitro study using rat dispersed luteal cells. | Prostaglandins & other lipid mediators 20070601 |
1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: bioisosteric replacement of the carboxylic acid and carboxamide moiety. | Bioorganic & medicinal chemistry 20070415 |
Effects of arachidonate metabolism inhibitors on basal and human chorionic gonadotropin-stimulated progesterone secretion by rat corpus luteum cells in vitro. | Prostaglandins & other lipid mediators 20070201 |
Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells. | Molecular and cellular biochemistry 20070101 |
Cytosolic PLA2 in zymogen granule fusion and amylase release: inhibition of GTP-induced fusion by arachidonyl trifluoromethyl ketone points to cPLA2 in G-protein-mediated secretory vesicle fusion. | Journal of biochemistry 20070101 |
The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans. | Diabetes 20070101 |
Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells. | Acta biochimica Polonica 20070101 |
Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells. | International journal of toxicology 20070101 |
Cytosolic phospholipase A alpha modulates NMDA neurotoxicity in mouse hippocampal cultures. | The European journal of neuroscience 20061201 |
Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils. | British journal of pharmacology 20061001 |
Pro-atherogenic effect of interleukin-4 in endothelial cells: modulation of oxidative stress, nitric oxide and monocyte chemoattractant protein-1 expression. | Atherosclerosis 20060801 |
Cytosolic phospholipase A2 inhibition attenuates ischemia-reperfusion injury in an isolated rat lung model. | Transplantation 20060627 |
Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice. | European journal of pharmacology 20060613 |
Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. | Cancer research 20060315 |
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. | British journal of pharmacology 20060301 |
Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium. | The Journal of physiology 20060101 |
Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation. | Experimental physiology 20060101 |
A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation. | The European journal of neuroscience 20060101 |
Effects of cannabinoids on the anxiety-like response in mice. | Pharmacological reports : PR 20060101 |
Phosphorylation of AMPA receptor subunits is differentially regulated by phospholipase A2 inhibitors. | Neuroscience letters 20051125 |
Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. | Journal of immunology (Baltimore, Md. : 1950) 20050915 |
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. | Journal of medicinal chemistry 20050811 |
Leptin rapidly activates PPARs in C2C12 muscle cells. | Biochemical and biophysical research communications 20050708 |
Vitamin C inhibits platelet expression of CD40 ligand. | Free radical biology & medicine 20050615 |
Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway. | Journal of neurophysiology 20050601 |
Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice. | Journal of applied physiology (Bethesda, Md. : 1985) 20050401 |
Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein. | Endothelium : journal of endothelial cell research 20050101 |
Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells. | Biochimica et biophysica acta 20041108 |
Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes. | Biochimica et biophysica acta 20041108 |
Intracerebroventricular injection of phospholipases A2 inhibitors modulates allodynia after facial carrageenan injection in mice. | Pain 20041101 |
Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity. | Kidney international 20041101 |
Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons. | European journal of pharmacology 20040913 |
gp91phox-dependent expression of platelet CD40 ligand. | Circulation 20040907 |
Release of choline in the isolated heart, an indicator of ischemic phospholipid degradation and its protection by ischemic preconditioning: no evidence for a role of phospholipase D. | Life sciences 20040813 |
Identifying pathways involved in leptin-dependent aggregation of human platelets. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040801 |
Comparison of cellular mechanisms underlying histamine release from rat mast cells induced by ionic and nonionic radiographic contrast media. | Investigative radiology 20040801 |
Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors. | Cancer research 20040701 |
Role of an aprotinin-sensitive protease in protein kinase Calpha-mediated activation of cytosolic phospholipase A2 by calcium ionophore (A23187) in pulmonary endothelium. | Cellular signalling 20040601 |
Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. | Molecular vision 20040517 |
Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation. | Aquatic toxicology (Amsterdam, Netherlands) 20040210 |
Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease. | Neuron 20040205 |
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. | Free radical biology & medicine 20031201 |
Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression. | Cardiovascular research 20031101 |
Phospholipase A2 plays an important role in myelin breakdown and phagocytosis during Wallerian degeneration. | Molecular and cellular neurosciences 20031101 |
17Beta-eEstradiol stimulates arachidonate release from human amnion-like WISH cells through a rapid mechanism involving a membrane receptor. | Endocrinology 20030801 |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. | American journal of physiology. Lung cellular and molecular physiology 20030501 |
Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism. | Carcinogenesis 20030501 |
Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture. | Neuroscience letters 20030227 |
Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants. | Brain research. Molecular brain research 20030131 |
Phospholipase A2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis. | Journal of cellular and molecular medicine 20030101 |
Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein. | Endothelium : journal of endothelial cell research 20030101 |
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death. | Cell death and differentiation 20021201 |
Essential role of Ca2+ -dependent phospholipase A2 in estradiol-induced lysosome activation. | American journal of physiology. Cell physiology 20021101 |
Role of cytoplasmic phospholipase A2 in endothelium-derived hyperpolarizing factor dilations of rat middle cerebral arteries. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021001 |
Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor. | Biochimica et biophysica acta 20020808 |
Endothelin-1-induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathway. | Biochemical pharmacology 20020801 |
Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools. | European journal of biochemistry 20020801 |
Involvement of oxidative stress in bee venom-induced inhibition of Na+/glucose cotransporter in renal proximal tubule cells. | Clinical and experimental pharmacology & physiology 20020701 |
Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent. | Biochemical pharmacology 20020615 |
Implication of three isoforms of PLA(2) in human T-cell proliferation. | FEBS letters 20020605 |
Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells. | Archives of biochemistry and biophysics 20020601 |
Role of p38 MAPK in the regulation of apoptosis signaling induced by TNF-alpha in differentiated PC12 cells. | Journal of biochemistry and molecular biology 20020531 |
Voltage independence of vasomotion in isolated irideal arterioles of the rat. | The Journal of physiology 20020401 |
Determination of the cell lytic properties of amphiphilic inhibitors of the cytosolic phospholipase A2 against human platelets by measuring the liberation of serotonin with high-performance liquid chromatography and fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020325 |
Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton. | Journal of medicinal chemistry 20020314 |
Possible implication of Golgi-nucleating function for the centrosome. | Biochemical and biophysical research communications 20020301 |
4-Bromophenacyl bromide induces Ca2+ influx in human gingival fibroblasts. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020301 |
Mechanisms of glutamate release in the rat spinal cord slices during metabolic inhibition. | Journal of neurotrauma 20020201 |
Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors. | Biochemical pharmacology 20020115 |
The central role of thromboxane and platelet activating factor receptors in ex vivo regulation of endotoxin-induced monocyte tissue factor activity in human whole blood. | Journal of endotoxin research 20020101 |
Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice. | The Journal of investigative dermatology 20011201 |
Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium. | American journal of physiology. Cell physiology 20011001 |
Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol. | Journal of lipid research 20011001 |
Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes. | The Journal of infectious diseases 20010915 |
Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. | Journal of immunology (Baltimore, Md. : 1950) 20010915 |
Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferation. | Biology of reproduction 20010801 |
Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion. | European journal of pharmacology 20010727 |
Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. | Reproduction (Cambridge, England) 20010701 |
Fatty acids inhibit anion secretion in rat colon: apical and basolateral action sites. | Pflugers Archiv : European journal of physiology 20010701 |
Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling. | Cardiovascular drugs and therapy 20010701 |
Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway. | The Journal of biological chemistry 20010608 |
Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2. | Pflugers Archiv : European journal of physiology 20010601 |
Arachidonic acid modulates the spatiotemporal characteristics of agonist-evoked Ca2+ waves in mouse pancreatic acinar cells. | The Journal of biological chemistry 20010518 |
The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway. | The Journal of biological chemistry 20010427 |
Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices. | British journal of pharmacology 20010401 |
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils. | Journal of leukocyte biology 20010401 |
Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells. | Calcified tissue international 20010301 |
Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'. | Bioorganic & medicinal chemistry letters 20010226 |
Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm. | Biochemical and biophysical research communications 20010223 |
Arachidonyl trifluoromethyl ketone induces lipid body formation in leukocytes. | Prostaglandins, leukotrienes, and essential fatty acids 20010101 |
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