200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 148741-30-4
148741-30-4 | 2-Propenethioamide, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-, (2E)-
CAS No: 148741-30-4 Catalog No: AG001L5Z MDL No:MFCD00236450
Product Description
Catalog Number:
AG001L5Z
Chemical Name:
2-Propenethioamide, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-, (2E)-
CAS Number:
148741-30-4
Molecular Formula:
C18H24N2OS
Molecular Weight:
316.4610
MDL Number:
MFCD00236450
IUPAC Name:
(E)-2-cyano-3-(3,5-ditert-butyl-4-hydroxyphenyl)prop-2-enethioamide
InChI:
InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+
InChI Key:
XRZYELWZLNAXGE-KPKJPENVSA-N
SMILES:
N#C/C(=C\c1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)/C(=S)N
Properties
Complexity:
477
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1
Exact Mass:
316.161g/mol
Formal Charge:
0
Heavy Atom Count:
22
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
316.463g/mol
Monoisotopic Mass:
316.161g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
102A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.7
Literature
| Title | Journal |
|---|---|
| Ligand-independent activation of the arylhydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment. | Biological chemistry 20111001 |
| Reciprocal regulation of 17beta-estradiol, interleukin-6 and interleukin-8 during growth and progression of epithelial ovarian cancer. | Cytokine 20090601 |
| Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation. | Molecular nutrition & food research 20080701 |
| Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010601 |
| Tyrphostin [correction of Tryphostin] AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements. | Biochemical pharmacology 20010115 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.