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148498-78-6 | ADRENOMEDULLIN (HUMAN)
CAS No: 148498-78-6 Catalog No: AG001KY6 MDL No:
Product Description
Catalog Number:
AG001KY6
Chemical Name:
ADRENOMEDULLIN (HUMAN)
CAS Number:
148498-78-6
IUPAC Name:
(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(4R,7S,13S,16S,19R)-19-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-13-benzyl-16-(3-carbamimidamidopropyl)-7-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-hydroxybutanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-carboxypropanoyl]amino]hexanoyl]amino]-4-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-5-amino-1-[[2-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-oxobutanoic acid
InChI:
InChI=1S/C264H406N80O77S3/c1-19-132(10)207(335-200(366)120-294-216(377)160(78-84-189(270)355)308-234(395)171(107-142-52-30-24-31-53-142)322-237(398)176(112-196(277)362)324-238(399)175(111-195(276)361)323-230(391)166(90-101-422-18)312-245(406)182(123-346)332-229(390)163(81-87-192(273)358)309-220(381)156(60-42-95-289-261(280)281)302-215(376)151(269)103-144-66-72-148(352)73-67-144)253(414)315-159(63-45-98-292-264(286)287)226(387)331-183(124-347)246(407)320-170(106-141-50-28-23-29-51-141)219(380)295-119-199(365)301-185-126-423-424-127-186(334-256(417)210(137(15)349)336-201(367)121-296-218(379)169(105-140-48-26-22-27-49-140)319-224(385)157(307-247(185)408)61-43-96-290-262(282)283)248(409)342-212(139(17)351)258(419)338-206(131(8)9)252(413)316-164(82-88-193(274)359)227(388)303-152(56-34-38-91-265)221(382)318-168(102-129(4)5)233(394)298-135(13)214(375)317-174(110-147-117-288-128-297-147)236(397)311-165(83-89-194(275)360)232(393)340-208(133(11)20-2)254(415)328-172(109-146-70-76-150(354)77-71-146)235(396)310-162(80-86-191(272)357)228(389)321-173(108-143-54-32-25-33-55-143)242(403)341-211(138(16)350)257(418)329-180(116-204(372)373)240(401)305-154(58-36-40-93-267)222(383)326-178(114-202(368)369)239(400)304-153(57-35-39-92-266)223(384)327-179(115-203(370)371)241(402)325-177(113-197(278)363)243(404)337-205(130(6)7)251(412)299-136(14)259(420)343-99-46-64-187(343)249(410)313-158(62-44-97-291-263(284)285)225(386)330-181(122-345)244(405)306-155(59-37-41-94-268)231(392)339-209(134(12)21-3)255(416)333-184(125-348)260(421)344-100-47-65-188(344)250(411)314-161(79-85-190(271)356)217(378)293-118-198(364)300-167(213(279)374)104-145-68-74-149(353)75-69-145/h22-33,48-55,66-77,117,128-139,151-188,205-212,345-354H,19-21,34-47,56-65,78-116,118-127,265-269H2,1-18H3,(H2,270,355)(H2,271,356)(H2,272,357)(H2,273,358)(H2,274,359)(H2,275,360)(H2,276,361)(H2,277,362)(H2,278,363)(H2,279,374)(H,288,297)(H,293,378)(H,294,377)(H,295,380)(H,296,379)(H,298,394)(H,299,412)(H,300,364)(H,301,365)(H,302,376)(H,303,388)(H,304,400)(H,305,401)(H,306,405)(H,307,408)(H,308,395)(H,309,381)(H,310,396)(H,311,397)(H,312,406)(H,313,410)(H,314,411)(H,315,414)(H,316,413)(H,317,375)(H,318,382)(H,319,385)(H,320,407)(H,321,389)(H,322,398)(H,323,391)(H,324,399)(H,325,402)(H,326,383)(H,327,384)(H,328,415)(H,329,418)(H,330,386)(H,331,387)(H,332,390)(H,333,416)(H,334,417)(H,335,366)(H,336,367)(H,337,404)(H,338,419)(H,339,392)(H,340,393)(H,341,403)(H,342,409)(H,368,369)(H,370,371)(H,372,373)(H4,280,281,289)(H4,282,283,290)(H4,284,285,291)(H4,286,287,292)/t132-,133-,134-,135-,136-,137+,138+,139+,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,187-,188-,205-,206-,207-,208-,209-,210-,211-,212-/m0/s1
InChI Key:
ULCUCJFASIJEOE-NPECTJMMSA-N
Properties
Complexity:
15400
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
54
Defined Bond Stereocenter Count:
0
Exact Mass:
6026.954g/mol
Formal Charge:
0
Heavy Atom Count:
424
Hydrogen Bond Acceptor Count:
90
Hydrogen Bond Donor Count:
90
Isotope Atom Count:
0
Molecular Weight:
6028.815g/mol
Monoisotopic Mass:
6024.948g/mol
Rotatable Bond Count:
193
Topological Polar Surface Area:
2690A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-28.6
Literature
| Title | Journal |
|---|---|
| A spontaneous, double-blind, double-dummy cross-over study on the effects of daily vardenafil on arterial stiffness in patients with vasculogenic erectile dysfunction. | International journal of cardiology 20121018 |
| Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium. | The American journal of pathology 20121001 |
| Biomarkers of brain damage in preterm infants. | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20121001 |
| Do sepsis biomarkers in the emergency room allow transition from bundled sepsis care to personalized patient care? | Current opinion in critical care 20120801 |
| Multiple endothelial biomarkers and noninvasive vascular function in the general population: the Gutenberg Health Study. | Hypertension (Dallas, Tex. : 1979) 20120801 |
| Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome. | Journal of the American College of Cardiology 20120724 |
| Peptides in postural orthostatic tachycardia syndrome: players or epiphenomena? | Journal of the American College of Cardiology 20120724 |
| The role of glutamic acid 73 in adrenomedullin interactions with rodent AM2 receptors. | Peptides 20120701 |
| Adrenomedullin inhibits norepinephrine-induced contraction of rat seminal vesicle. | Urology 20120701 |
| New directions in cardiovascular risk assessment: the role of secondary risk stratification markers. | International journal of clinical practice 20120701 |
| Adrenomedullin, a neuropeptide with immunoregulatory properties induces semi-mature tolerogenic dendritic cells. | Immunology 20120601 |
| Adrenomedullin promotes human endothelial cell proliferation via HIF-1α. | Molecular and cellular biochemistry 20120601 |
| Biomarkers and community-acquired pneumonia: tailoring management with biological data. | Seminars in respiratory and critical care medicine 20120601 |
| Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes. | British journal of pharmacology 20120501 |
| Prognostic power of proadrenomedullin in community-acquired pneumonia is independent of aetiology. | The European respiratory journal 20120501 |
| Haemodynamic, endocrine and renal actions of adrenomedullin 5 in an ovine model of heart failure. | Clinical science (London, England : 1979) 20120501 |
| The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin. | Reproductive sciences (Thousand Oaks, Calif.) 20120501 |
| Cardiac biomarkers, mortality, and post-traumatic stress disorder in military veterans. | The American journal of cardiology 20120415 |
| Adrenomedullin-epinephrine cotreatment enhances cardiac output and left ventricular function by energetically neutral mechanisms. | American journal of physiology. Heart and circulatory physiology 20120415 |
| Cardiovascular and hormonal responses to static handgrip in young and older healthy men. | European journal of applied physiology 20120401 |
| Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. | Gynecologic oncology 20120401 |
| Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide. | American journal of physiology. Heart and circulatory physiology 20120301 |
| Cardiovascular effects of the intracerebroventricular injection of adrenomedullin: roles of the peripheral vasopressin and central cholinergic systems. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120301 |
| Attenuation of hyperoxia-induced lung injury in rats by adrenomedullin. | Inflammation 20120201 |
| Adrenomedullin mediates adipose tissue-derived stem cell-induced restoration of erectile function in diabetic rats. | The journal of sexual medicine 20120201 |
| Biomarkers associated with pulse pressure in African-Americans and non-Hispanic whites. | American journal of hypertension 20120201 |
| Extracellular signal-regulated kinase 1/2 activation is involved in intermedin1-53 attenuating myocardial oxidative stress injury induced by ischemia/reperfusion. | Peptides 20120201 |
| Evaluation of multiple biomarkers of cardiovascular stress for risk prediction and guiding medical therapy in patients with stable coronary disease. | Circulation 20120117 |
| Ethanol consumption alters the expression and reactivity of adrenomedullin in the rat mesenteric arterial bed. | Alcohol and alcoholism (Oxford, Oxfordshire) 20120101 |
| Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells. | PloS one 20120101 |
| Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin. | Journal of experimental & clinical cancer research : CR 20120101 |
| Salivary defense proteins: their network and role in innate and acquired oral immunity. | International journal of molecular sciences 20120101 |
| Anti-inflammatory effects of adrenomedullin on acute lung injury induced by Carrageenan in mice. | Mediators of inflammation 20120101 |
| Evidence for a functional adrenomedullin signaling pathway in the mouse retina. | Molecular vision 20120101 |
| Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice. | PloS one 20120101 |
| Chronic ethanol consumption reduces adrenomedullin-induced relaxation in the isolated rat aorta. | Alcohol (Fayetteville, N.Y.) 20111201 |
| Signal transduction pathways mediating the effect of adrenomedullin on osteoblast survival. | Journal of cellular biochemistry 20111201 |
| The antifibrosis effect of adrenomedullin in human lung fibroblasts. | Experimental lung research 20111201 |
| Vascular contribution of adrenomedullin to microcirculatory improvement in experimental colitis. | European journal of pharmacology 20111130 |
| Hypoxia induced expression of histone lysine demethylases: implications in oxygen-dependent retinal neovascular diseases. | Biochemical and biophysical research communications 20111118 |
| Hormonal and plasma volume changes after presyncope. | European journal of clinical investigation 20111101 |
| Potential role of intermedin/adrenomedullin 2 in early embryonic development in rats. | Regulatory peptides 20111010 |
| Adrenomedullin inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and MMPs, COX-2 and PGE2 production. | Inflammation 20111001 |
| Inhibition of lipopolysaccharide-induced microglia activation by calcitonin gene related peptide and adrenomedullin. | Molecular and cellular neurosciences 20111001 |
| Daikenchuto (TU-100) ameliorates colon microvascular dysfunction via endogenous adrenomedullin in Crohn's disease rat model. | Journal of gastroenterology 20111001 |
| [Epicardial adipose tissue and its association to plasma adrenomedullin levels in patients with metabolic syndrome]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20111001 |
| Adrenomedulline improves ischemic left colonic anastomotic healing in an experimental rodent model. | Clinics (Sao Paulo, Brazil) 20111001 |
| Effects of onion extract on endogenous vascular H2S and adrenomedulin in rat atherosclerosis. | Current pharmaceutical biotechnology 20110901 |
| Induction of LYVE-1/stabilin-2-positive liver sinusoidal endothelial-like cells from embryoid bodies by modulation of adrenomedullin-RAMP2 signaling. | Peptides 20110901 |
| Blockade of adrenomedullin receptors reverses morphine tolerance and its neurochemical mechanisms. | Behavioural brain research 20110801 |
| Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro. | Neuropeptides 20110801 |
| Disulfide bond cleavage in TEMPO-free radical initiated peptide sequencing mass spectrometry. | Journal of mass spectrometry : JMS 20110801 |
| Characterization of iodinated adrenomedullin derivatives suitable for lung nuclear medicine. | Nuclear medicine and biology 20110801 |
| Adrenomedullin mRNA expression in placenta of preeclamptic women. | Ginekologia polska 20110801 |
| Hemodynamic, hormonal, and renal actions of adrenomedullin-5 in normal conscious sheep. | Journal of cardiovascular pharmacology 20110701 |
| The expression and regulation of adrenomedullin in the human endometrium: a candidate for endometrial repair. | Endocrinology 20110701 |
| Adrenomedullin protects against fructose-induced insulin resistance and myocardial hypertrophy in rats. | Peptides 20110701 |
| [Effect and mechanism of intermedin in acute rat cardiac ischemic injury]. | Fa yi xue za zhi 20110601 |
| Modulation of plasma adrenomedullin by epinephrine infusion during head up tilt. | European journal of applied physiology 20110301 |
| Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading. | Hypertension research : official journal of the Japanese Society of Hypertension 20110301 |
| Adrenomedullin attenuates aortic cross-clamping-induced myocardial injury in rats. | American journal of surgery 20110201 |
| Calcitonin gene-related peptide- and adrenomedullin-induced facilitation of calcium current in submandibular ganglion. | Archives of oral biology 20110201 |
| Changes of globin expression in the Japanese medaka (Oryzias latipes) in response to acute and chronic hypoxia. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20110201 |
| Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity. | Cytokine 20110201 |
| A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese. | Clinica chimica acta; international journal of clinical chemistry 20110130 |
| Adrenomedullin reduces expression of adhesion molecules on lymphatic endothelial cells. | Regulatory peptides 20110117 |
| Pre-treatment of adrenomedullin suppresses cerebral edema caused by transient focal cerebral ischemia in rats detected by magnetic resonance imaging. | Brain research bulletin 20110115 |
| The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort. | PloS one 20110101 |
| Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis. | Respiratory research 20110101 |
| Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats. | Journal of biomedical science 20110101 |
| Peripheral administration of human adrenomedullin and its binding protein attenuates stroke-induced apoptosis and brain injury in rats. | Molecular medicine (Cambridge, Mass.) 20110101 |
| Optimised patient transfer using an innovative multidisciplinary assessment in Kanton Aargau (OPTIMA I): an observational survey in lower respiratory tract infections. | Swiss medical weekly 20110101 |
| Adrenomedullin in rat follicles and corpora lutea: expression, functions and interaction with endothelin-1. | Reproductive biology and endocrinology : RB&E 20110101 |
| Adrenomedullin worsens skin necrosis in rats subjected to vincristine-induced extravasation. | Clinical and experimental dermatology 20101201 |
| Adrenomedullin attenuates ventilator-induced lung injury in mice. | Thorax 20101201 |
| Resuscitation of uncontrolled traumatic hemorrhage induced by severe liver injury: the use of human adrenomedullin and adrenomedullin binding protein-1. | The Journal of trauma 20101201 |
| Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function. | European journal of pharmacology 20101010 |
| Adrenomedullin up-regulates osteopontin and attenuates vascular calcification via the cAMP/PKA signaling pathway. | Acta pharmacologica Sinica 20101001 |
| The first clinical pilot study of intravenous adrenomedullin administration in patients with acute myocardial infarction. | Journal of cardiovascular pharmacology 20101001 |
| A role for protein kinase C-dependent upregulation of adrenomedullin in the development of morphine tolerance in male rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100915 |
| Expression of trophic amidated peptides and their receptors in benign and malignant pheochromocytomas: high expression of adrenomedullin RDC1 receptor and implication in tumoral cell survival. | Endocrine-related cancer 20100901 |
| Expression of adrenomedullin in human oviduct, its regulation by the hormonal cycle and contact with spermatozoa, and its effect on ciliary beat frequency of the oviductal epithelium. | The Journal of clinical endocrinology and metabolism 20100901 |
| Attenuation of renal ischemia and reperfusion injury by human adrenomedullin and its binding protein. | The Journal of surgical research 20100901 |
| Impaired cerebral blood flow autoregulation during posttraumatic arterial hypotension after fluid percussion brain injury is prevented by phenylephrine in female but exacerbated in male piglets by extracellular signal-related kinase mitogen-activated protein kinase upregulation. | Critical care medicine 20100901 |
| Adrenomedullin relaxes rat uterine artery: mechanisms and influence of pregnancy and estradiol. | Endocrinology 20100901 |
| Imbalance of the autonomic nervous system at night in women with gestational diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20100901 |
| Adrenomedullin regulates sperm motility and oviductal ciliary beat via cyclic adenosine 5'-monophosphate/protein kinase A and nitric oxide. | Endocrinology 20100701 |
| Anti-colitis and -adhesion effects of daikenchuto via endogenous adrenomedullin enhancement in Crohn's disease mouse model. | Journal of Crohn's & colitis 20100601 |
| Human adrenomedullin and its binding protein ameliorate sepsis-induced organ injury and mortality in jaundiced rats. | Peptides 20100501 |
| Adrenomedullin 2 attenuates the pressor but not adrenal responses to angiotensin II in conscious sheep. | Peptides 20100501 |
| Mid-regional pro-adrenomedullin as a novel predictor of mortality in patients with chronic heart failure. | European journal of heart failure 20100501 |
| Calcitonin gene-related peptide- and adrenomedullin-induced facilitation of calcium current by different signal pathways in nucleus tractus solitarius. | Brain research 20100423 |
| The role of nitric oxide and potassium channels in the effect of adrenomedullin in human internal thoracic arteries. | Regulatory peptides 20100409 |
| Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine. | The pharmacogenomics journal 20100401 |
| Vasoactive mediators in patients with acute liver failure treated with albumin dialysis. | Liver international : official journal of the International Association for the Study of the Liver 20100401 |
| Hemodynamic and hormonal effects of exogenous adrenomedullin administration in humans and relationship to insulin resistance. | Hypertension research : official journal of the Japanese Society of Hypertension 20100401 |
| Aldosterone antisecretagogue and antihypertensive actions of adrenomedullin in patients with primary aldosteronism. | Hypertension research : official journal of the Japanese Society of Hypertension 20100401 |
| Lack of adrenomedullin affects growth and differentiation of adult neural stem/progenitor cells. | Cell and tissue research 20100401 |
| Improving risk stratification in heart failure: a role for new biomarkers? | European journal of heart failure 20100401 |
| Kidney is in trouble with mediators. | Bosnian journal of basic medical sciences 20100401 |
| Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium. | Basic research in cardiology 20100301 |
| Intermedin inhibits vascular calcification by increasing the level of matrix gamma-carboxyglutamic acid protein. | Cardiovascular research 20100301 |
| Diabetes-associated alterations in volatile anesthetic actions on contractile response to norepinephrine in isolated mesenteric resistance arteries. | Anesthesiology 20100301 |
| Gastrointestinal peptides and bone health. | Current opinion in endocrinology, diabetes, and obesity 20100201 |
| Effect of corticosteroids and progesterone on adrenomedullin output and expression in human fetal membranes and placenta trophoblasts. | American journal of obstetrics and gynecology 20100201 |
| Role of selenium compounds on tyrosine hydroxylase activity, adrenomedullin and total RNA levels in hearts of rats. | Regulatory peptides 20100108 |
| Adrenomedullin protects against hypoxia/reoxygenation-induced cell death by suppression of reactive oxygen species via thiol redox systems. | FEBS letters 20100104 |
| Correlation of electroretinography b-wave absolute latency, plasma levels of human basic fibroblast growth factor, vascular endothelial growth factor, soluble fatty acid synthase, and adrenomedullin in diabetic retinopathy. | Journal of diabetes and its complications 20100101 |
| Biochemical markers of perinatal brain damage. | Frontiers in bioscience (Scholar edition) 20100101 |
| Biomarkers of myocardial injury after cardiac arrest or myocardial ischemia. | Frontiers in bioscience (Scholar edition) 20100101 |
| Adrenomedullin gene delivery is cardio-protective in a model of chronic nitric oxide deficiency combining pressure overload, oxidative stress and cardiomyocyte hypertrophy. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101 |
| [Incretory function of the kidney]. | Uspekhi fiziologicheskikh nauk 20100101 |
| Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation. | Arthritis research & therapy 20100101 |
| Coexpression of adrenomedullin and its receptor component proteins in the reproductive system of the rat during gestation. | Reproductive biology and endocrinology : RB&E 20100101 |
| Inhibition of oxygen-induced hypoxia-inducible factor-1alpha degradation unmasks estradiol induction of vascular endothelial growth factor expression in ECC-1 cancer cells in vitro. | Endocrinology 20091201 |
| Increased plasma levels of the mature and intermediate forms of adrenomedullin in obesity. | Regulatory peptides 20091127 |
| Protein kinase A-dependent suppression of reactive oxygen species in transient focal ischemia in adrenomedullin-deficient mice. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20091101 |
| Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability. | American journal of physiology. Lung cellular and molecular physiology 20091101 |
| A possible relationship between brain-derived adrenomedullin and oxytocin in the regulation of sodium balance. | The Journal of endocrinology 20091101 |
| Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion. | Apoptosis : an international journal on programmed cell death 20091101 |
| Endothelial markers may link kidney function to cardiovascular events in type 2 diabetes. | Diabetes care 20091001 |
| Intracoronary intermedin 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin receptors and beta-adrenoreceptor-mediated nitric oxide release. | Journal of applied physiology (Bethesda, Md. : 1985) 20091001 |
| Adrenomedullin treatment reduces intestinal inflammation and maintains epithelial barrier function in mice administered dextran sulphate sodium. | Microbiology and immunology 20091001 |
| [Intermedin (IMD) gene expression in hypertrophic cardiac myocyte of renal vascular hypertension rats and the intervention of Valsartan, Amlodipine and Enalapril in the expression]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20091001 |
| Midregional proadrenomedullin as a prognostic tool in community-acquired pneumonia. | Chest 20090901 |
| Characterization of the adrenomedullin receptor acting as the target of a new radiopharmaceutical biomolecule for lung imaging. | European journal of pharmacology 20090901 |
| Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion. | Apoptosis : an international journal on programmed cell death 20090901 |
| Plasma urocortin 1 in human heart failure. | Circulation. Heart failure 20090901 |
| Centrally administered adrenomedullin 5 activates oxytocin-secreting neurons in the hypothalamus and elevates plasma oxytocin level in rats. | The Journal of endocrinology 20090801 |
| Mid-regional pro-adrenomedullin is associated with pulse pressure, left ventricular mass, and albuminuria in African Americans with hypertension. | American journal of hypertension 20090801 |
| The renin-angiotensin system, adrenomedullins and urotensin II in the kidney: possible renoprotection via the kidney peptide systems. | Peptides 20090801 |
| Effect of adrenotensin on cell proliferation is mediated by angiotensin II in cultured rat mesangial cells. | Acta pharmacologica Sinica 20090801 |
| The changes of plasma malondialdehyde, nitric oxide, and adrenomedullin levels in patients with preeclampsia. | Hypertension in pregnancy 20090801 |
| Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain. | Brain research 20090714 |
| Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats. | Molecular therapy : the journal of the American Society of Gene Therapy 20090701 |
| Adrenomedullin reduces intestinal epithelial permeability in vivo and in vitro. | American journal of physiology. Gastrointestinal and liver physiology 20090701 |
| Molecular imaging of monocrotaline-induced pulmonary vascular disease with radiolabeled linear adrenomedullin. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701 |
| Adrenomedullin ameliorates ischemia reperfusion injury in rat livers. | [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20090701 |
| Adrenomedullin reduces antioxidant defense system and enhances kidney tissue damage in cadmium and lead exposed rats. | Environmental toxicology 20090601 |
| Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090601 |
| Plasma MR-proADM correlates to BMI and decreases in relation to leptin after gastric bypass surgery. | Obesity (Silver Spring, Md.) 20090601 |
| Circulating hormone adrenomedullin and its binding protein protect neural cells from hypoxia-induced apoptosis. | Biochimica et biophysica acta 20090501 |
| Effects of long-term intravenous administration of adrenomedullin (AM) plus hANP therapy in acute decompensated heart failure: a pilot study. | Circulation journal : official journal of the Japanese Circulation Society 20090501 |
| Significance of salivary adrenomedullin in the maintenance of oral health: stimulation of oral cell proliferation and antibacterial properties. | Regulatory peptides 20090410 |
| Paracrine action mediate the antifibrotic effect of transplanted mesenchymal stem cells in a rat model of global heart failure. | Molecular biology reports 20090401 |
| Relationships between plasma adrenomedullin concentration and systolic time intervals during static handgrip in patients with heart failure. | Clinical physiology and functional imaging 20090401 |
| Adrenomedullin improves cardiac expression of heat-shock protein 72 and tolerance against ischemia/reperfusion injury in insulin-resistant rats. | Endocrinology 20090301 |
| The involvement of CGRP, adrenomedullin, and sensory nerves in remote vasomotor responses within the hamster cheek pouch microcirculation. | Microvascular research 20090301 |
| New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: mitochondrial ion channels and cardioprotection. | Journal of pharmacological sciences 20090301 |
| Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study. | Kidney international 20090201 |
| Predicting progression in nondiabetic kidney disease: the importance of cardiorenal interactions. | Kidney international 20090201 |
| Expression of adrenomedullin in human ovaries, ovarian sex cord-stromal tumors and cultured granulosa-luteal cells. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090201 |
| The Krüppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes. | Biochemical and biophysical research communications 20090130 |
| Structure-function analysis of RAMP1 by alanine mutagenesis. | Biochemistry 20090113 |
| Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat. | Regulatory peptides 20090108 |
| Adrenomedullin-induced relaxation of rat brain pericytes is related to the reduced phosphorylation of myosin light chain through the cAMP/PKA signaling pathway. | Neuroscience letters 20090102 |
| Variations within oxygen-regulated gene expression in humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20090101 |
| Reversing established sepsis in rats with human vasoactive hormone adrenomedullin and its binding protein. | Molecular medicine (Cambridge, Mass.) 20090101 |
| Therapeutic targets in pulmonary arterial hypertension. | Pharmacology & therapeutics 20090101 |
| Intermedin (adrenomedullin-2): a potential protective role in human aortic endothelial cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101 |
| Plasma adrenomedullin and endothelin-1 levels are reduced and Raynaud's phenomenon improved by daily tadalafil administration in male patients with systemic sclerosis. | Journal of biological regulators and homeostatic agents 20090101 |
| Potential markers of preeclampsia--a review. | Reproductive biology and endocrinology : RB&E 20090101 |
| Midregional pro-adrenomedullin in addition to b-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study. | Critical care (London, England) 20090101 |
| New markers of neonatal neurology. | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20090101 |
| The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment. | PloS one 20090101 |
| Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema. | Cardiovascular research 20081201 |
| Intermedin ameliorates vascular and renal injury by inhibition of oxidative stress. | American journal of physiology. Renal physiology 20081201 |
| Malondialdehyde, nitric oxide and adrenomedullin levels in patients with primary dysmenorrhea. | The journal of obstetrics and gynaecology research 20081201 |
| Changes in natriuretic peptides, apelin and adrenomedullin after off-pump and on-pump coronary artery bypass surgery. | The Journal of cardiovascular surgery 20081201 |
| Deferroxamine preconditioning promotes long-lasting retinal ischemic tolerance. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081201 |
| Human adrenomedullin up-regulates interleukin-13 receptor alpha2 chain in prostate cancer in vitro and in vivo: a novel approach to sensitize prostate cancer to anticancer therapy. | Cancer research 20081115 |
| Role of adrenomedullin system in lipid metabolism and its signaling mechanism in cultured adipocytes. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
| Acute and chronic responses associated with adrenomedullin administration in experimental colitis. | Peptides 20081101 |
| Use of adrenomedullin derivatives for molecular imaging of pulmonary circulation. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20081101 |
| Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function. | Molecular pharmacology 20081001 |
| Adrenomedullin enhances baroreceptor reflex response via cAMP/PKA signaling in nucleus tractus solitarii of rats. | Neuropharmacology 20081001 |
| A pilot study on level of blood vasoactive factors in prehypertensive and hypertensive patients. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001 |
| Molecular characterization of calcitonin gene-related peptide (CGRP) related peptides (CGRP, amylin, adrenomedullin and adrenomedullin-2/intermedin) in goldfish (Carassius auratus): cloning and distribution. | Peptides 20080901 |
| PARP-1 modulates deferoxamine-induced HIF-1alpha accumulation through the regulation of nitric oxide and oxidative stress. | Journal of cellular biochemistry 20080815 |
| Coexpression of adrenomedullin and its receptors in the reproductive system of the rat: effects on steroid secretion in rat ovary. | Biology of reproduction 20080801 |
| Effect of adrenomedullin on hepatic damage in hepatic ischaemia/reperfusion injury in rats. | Liver international : official journal of the International Association for the Study of the Liver 20080801 |
| Adrenomedullin protects neurons against oxygen glucose deprivation stress in an autocrine and paracrine manner. | Journal of neurochemistry 20080801 |
| Intermedin/adrenomedullin-2 (IMD/AM2) relaxes rat main pulmonary arterial rings via cGMP-dependent pathway: role of nitric oxide and large conductance calcium-activated potassium channels (BK(Ca)). | Peptides 20080801 |
| Up-regulation of ADM and SEPX1 in the lymphoblastoid cells of patients in monozygotic twins discordant for schizophrenia. | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20080705 |
| The effects of isoflurane on adrenomedullin-induced haemodynamic responses in pithed rats. | European journal of anaesthesiology 20080701 |
| Adrenomedullin expression is up-regulated by acute hypobaric hypoxia in the cerebral cortex of the adult rat. | Brain pathology (Zurich, Switzerland) 20080701 |
| Human vasoactive hormone adrenomedullin and its binding protein rescue experimental animals from shock. | Peptides 20080701 |
| Adrenomedullin-2/intermedin induces cAMP accumulation in dissociated rat spinal cord cells: evidence for the existence of a distinct class of sites of action. | Journal of molecular neuroscience : MN 20080701 |
| Adrenomedullin acts in the lateral parabrachial nucleus to increase arterial blood pressure through mechanisms mediated by glutamate and nitric oxide. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
| A novel heterozygous HIF2AM535I mutation reinforces the role of oxygen sensing pathway disturbances in the pathogenesis of familial erythrocytosis. | Haematologica 20080701 |
| Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists. | European journal of pharmacology 20080610 |
| Aortic cross-clamping-induced spinal cord oxidative stress in rabbits: the role of a novel antioxidant adrenomedullin. | The Journal of surgical research 20080601 |
| International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor. | Pharmacological reviews 20080601 |
| Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway. | Journal of cellular physiology 20080401 |
| Adrenomedullin in the rat testis. I: Its production, actions on testosterone secretion, regulation by human chorionic gonadotropin, and its interaction with endothelin 1 in the leydig cell. | Biology of reproduction 20080401 |
| Plasma adrenomedullin as an independent predictor of future cardiovascular events in high-risk patients: comparison with C-reactive protein and adiponectin. | Peptides 20080401 |
| Possible involvement of Akt activity in endothelial dysfunction in type 2 diabetic mice. | Journal of pharmacological sciences 20080401 |
| Blockade of endogenous proinflammatory cytokines ameliorates endothelial dysfunction in obese Zucker rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20080401 |
| The effect of adrenomedullin on rats exposed to lead. | Journal of applied toxicology : JAT 20080301 |
| Prohormones: novel biomarkers for corticosteroids in septic shock? | Intensive care medicine 20080301 |
| The influence of corticosteroids on the release of novel biomarkers in human endotoxemia. | Intensive care medicine 20080301 |
| Protective role of adrenomedullin in burn-induced remote organ damage in the rat. | Regulatory peptides 20080207 |
| Expression of pulmonary vasoactive factors after sevoflurane anaesthesia in rats: a quantitative real-time polymerase chain reaction study. | British journal of anaesthesia 20080201 |
| Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells. | European journal of pharmacology 20080128 |
| Adrenomedullin, an autocrine/paracrine factor induced by androgen withdrawal, stimulates 'neuroendocrine phenotype' in LNCaP prostate tumor cells. | Oncogene 20080117 |
| Infarct size limitation by adrenomedullin: protein kinase A but not PI3-kinase is linked to mitochondrial KCa channels. | Cardiovascular research 20080115 |
| Cyclic AMP-independent CGRP8-37-sensitive receptors mediate adrenomedullin-induced decrease of CaCl2-contraction in pregnant rat mesenteric artery. | Journal of vascular research 20080101 |
| Influence of atenolol and nifedipine on nitric-oxide deficient cardiomyocyte hypertrophy and expression of the cardio-endocrine peptide intermedin and its receptor components. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
| Effects of adrenomedullin on the cell numbers and apoptosis of endothelial progenitor cells. | Clinical and investigative medicine. Medecine clinique et experimentale 20080101 |
| Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits. | Arthritis research & therapy 20080101 |
| Desensitization and re-sensitization of CGRP receptor function in human neuroblastoma SK-N-MC cells. | European journal of pharmacology 20071222 |
| Exogenous adrenomedullin prevents and reverses hypodynamic circulation and pulmonary hypertension in ovine endotoxaemia. | British journal of anaesthesia 20071201 |
| Role of hypoxia and cAMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scarring in autoimmune-associated congenital heart block. | Arthritis and rheumatism 20071201 |
| Pregnancy enhances the prejunctional vasodilator response to adrenomedullin in selective regions of the arterial bed of Wistar rats. | Reproductive sciences (Thousand Oaks, Calif.) 20071201 |
| Effect of aging on the expression of adrenomedullin and its receptor component proteins in the male reproductive system of the rat. | The journals of gerontology. Series A, Biological sciences and medical sciences 20071201 |
| The effect of adrenomedullin on the L-type calcium current in myocytes from septic shock rats: signaling pathway. | American journal of physiology. Heart and circulatory physiology 20071101 |
| Mice heterozygous for adrenomedullin exhibit a more extreme inflammatory response to endotoxin-induced septic shock. | Peptides 20071101 |
| Inhaled nitric oxide combined with prostacyclin and adrenomedullin in acute respiratory failure with pulmonary hypertension in piglets. | Pediatric pulmonology 20071101 |
| Adrenomedullin reduces the severity of cerulein-induced acute pancreatitis. | Peptides 20071101 |
| Elevated plasma adrenomedullin and vascular manifestations in patients with systemic sclerosis. | The Journal of rheumatology 20071101 |
| Vasoactive hormone adrenomedullin and its binding protein: anti-inflammatory effects by up-regulating peroxisome proliferator-activated receptor-gamma. | Journal of immunology (Baltimore, Md. : 1950) 20071101 |
| Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis. | Endothelium : journal of endothelial cell research 20071101 |
| Adrenomedullin reduces gender-dependent loss of hypotensive cerebrovasodilation after newborn brain injury through activation of ATP-dependent K channels. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20071001 |
| The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death. | American journal of physiology. Regulatory, integrative and comparative physiology 20071001 |
| Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity. | American journal of physiology. Heart and circulatory physiology 20071001 |
| Up-regulation of adrenomedullin gene expression in the regenerating rat adrenal cortex. | International journal of molecular medicine 20071001 |
| [Effects of adrenomedullin on angiotensin II-induced collagen synthesis in vascular adventitial fibroblasts]. | Zhonghua xin xue guan bing za zhi 20070901 |
| Dissolution of bio-active dentine matrix components by mineral trioxide aggregate. | Journal of dentistry 20070801 |
| Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases. | Molecular pharmacology 20070701 |
| Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study. | Circulation 20070619 |
| In vitro effects of adrenomedullin and calcitonin gene related peptide on the release of serotonin and amino acids from rat dorsal spinal cord. | Neuroscience letters 20070615 |
| Adrenomedullin insufficiency increases allergen-induced airway hyperresponsiveness in mice. | Journal of applied physiology (Bethesda, Md. : 1985) 20070601 |
| The relationship between adrenomedullin, metabolic factors, and vascular function in individuals with type 2 diabetes. | Diabetes care 20070601 |
| Plasma levels of adrenomedullin, a vasoactive peptide, in type 2 diabetic patients with and without retinopathy. | Minerva endocrinologica 20070601 |
| [Effect of adrenomedullin on neuron apoptosis and early growth response gene-1 after focal ischemia/ reperfusion in rats]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070601 |
| Evaluation of hormone replacement therapy which may have an adrenomedullin-mediated protective effect on cardiovascular disorders. | Aging clinical and experimental research 20070601 |
| Omapatrilat enhances adrenomedullin's reduction of cardiomyocyte cell death. | European journal of pharmacology 20070521 |
| Malon dialdehyde, nitrite and adrenomedullin levels in patients with premenstrual syndrome. | Archives of gynecology and obstetrics 20070501 |
| Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats. | Peptides 20070501 |
| Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study. | Journal of the American College of Cardiology 20070410 |
| The level of adrenomedullin immunoreactivity in seminal fluid is higher in oligozoospermic subjects and correlates with semen biochemical parameters. | European journal of obstetrics, gynecology, and reproductive biology 20070401 |
| Adrenomedullin inhibits angiotensin II-induced oxidative stress via Csk-mediated inhibition of Src activity. | American journal of physiology. Heart and circulatory physiology 20070401 |
| Adrenomedullin-2, a novel calcitonin/calcitonin-gene-related peptide family peptide, relaxes rat mesenteric artery: influence of pregnancy. | Endocrinology 20070401 |
| Adrenomedullin and its receptor components in adipose tissues: Differences between white and brown fats and the effects of adrenergic stimulation. | Peptides 20070401 |
| Adrenomedullin fails to reduce cadmium-induced oxidative damage in rat liver. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070401 |
| The myocardial response to adrenomedullin involves increased cAMP generation as well as augmented Akt phosphorylation. | Peptides 20070401 |
| Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery. | British journal of pharmacology 20070301 |
| Combination therapy and new types of agents for pulmonary arterial hypertension. | Clinics in chest medicine 20070301 |
| Changes in expression of adrenomedullin in the myocardium of streptozotocin-induced diabetic rats. | Chinese medical journal 20070205 |
| Adrenomedullin and adrenomedullin-binding protein-1 downregulate inflammatory cytokines and attenuate tissue injury after gut ischemia-reperfusion. | Surgery 20070201 |
| Interaction of adrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis. | FEMS immunology and medical microbiology 20070201 |
| Comparative evaluation of B-type natriuretic peptide, mid-regional pro-A-type natriuretic peptide, mid-regional pro-adrenomedullin, and Copeptin to predict 1-year mortality in patients with acute destabilized heart failure. | Journal of cardiac failure 20070201 |
| Adrenomedullin facilitates reinnervation of phenol-injured perivascular nerves in the rat mesenteric resistance artery. | Neuroscience 20070119 |
| Adrenomedullin: molecular mechanisms and its role in cardiac disease. | Amino acids 20070101 |
| Vascular hyperresponsiveness to adrenomedullin during pregnancy is associated with increased generation of cyclic nucleotides in rat mesenteric artery. | Biology of reproduction 20070101 |
| Renal adrenomedullin and high altitude diuresis. | Physiological research 20070101 |
| Adrenomedullin gene expression and peptide levels in the heart and blood vessels of streptozotocin-diabetic rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070101 |
| Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20070101 |
| Expression of calcitonin gene-related peptide, adrenomedullin, and receptor modifying proteins in human adipose tissue and alteration in their expression with menopause status. | Menopause (New York, N.Y.) 20070101 |
| Differential effects of an anti-oxidant intervention on cardiomyocyte expression of adrenomedullin and intermedin and their receptor components in chronic nitric oxide deficiency. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101 |
| Adrenomedullin and adrenomedullin binding protein-1 protect endothelium-dependent vascular relaxation in sepsis. | Molecular medicine (Cambridge, Mass.) 20070101 |
| The molecules: mechanisms of arterial vasodilatation observed in the splanchnic and systemic circulation in portal hypertension. | Journal of clinical gastroenterology 20070101 |
| Antimicrobial activity does not predict cytokine response to adrenomedullin or its shortened derivatives. | Mediators of inflammation 20070101 |
| Relaxing effects of adrenomedullin in rat mesenteric resistance arteries. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101 |
| Vasodilator mechanism of intermedin/adrenomedullin-2 in anesthetized rats. | Proceedings of the Western Pharmacology Society 20070101 |
| Characterization of the snake venom ligand [125I]-DNP binding to natriuretic peptide receptor-A in human artery and potent DNP mediated vasodilatation. | British journal of pharmacology 20061201 |
| Effect of prolonged dynamic exercise on plasma adrenomedullin concentration in healthy young men. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201 |
| Intermedin1-53 protects the heart against isoproterenol-induced ischemic injury in rats. | European journal of pharmacology 20061107 |
| Effect of adrenergic blockade on plasma adrenomedullin concentration during static handgrip in patients with heart failure. | Clinical physiology and functional imaging 20061101 |
| Participation of adrenomedullin and its relation with vascular endothelial growth factor in androgen regulation of prostatic blood flow in vivo. | Urology 20061101 |
| Cardiovascular and neurohormonal responses to lower body negative pressure (LBNP): effect of training and 3 day bed rest. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101 |
| A role for adrenomedullin as a pain-related peptide in the rat. | Proceedings of the National Academy of Sciences of the United States of America 20061024 |
| Plasma adrenomedullin levels in patients with polycystic ovary syndrome. | Fertility and sterility 20061001 |
| Chronic effect of combined treatment with omapatrilat and adrenomedullin on the progression of heart failure in rats. | American journal of hypertension 20061001 |
| Regulation of adrenomedullin release from human endothelial cells by sex steroids and angiotensin-II. | The Journal of endocrinology 20061001 |
| Vasodilator effects of adrenomedullin on retinal arterioles in streptozotocin-induced diabetic rats. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20061001 |
| Plasma adrenomedullin and endothelin-1 concentration during low-dose dobutamine infusion: Relationship between pulmonary uptake and pulmonary vascular pressure/flow characteristics. | Regulatory peptides 20060911 |
| Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders. | Pharmacology & therapeutics 20060901 |
| Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells. | Human reproduction (Oxford, England) 20060901 |
| Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats. | The Journal of pharmacology and experimental therapeutics 20060901 |
| Adrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitors. | Arteriosclerosis, thrombosis, and vascular biology 20060901 |
| Effect of betamethasone in vivo on placental adrenomedullin in human pregnancy. | Journal of the Society for Gynecologic Investigation 20060901 |
| Adrenomedullin peptide: gene expression of adrenomedullin, its receptors and receptor activity modifying proteins, and receptor binding in rat testis--actions on testosterone secretion. | Biology of reproduction 20060801 |
| Effect of intermedin/adrenomedullin-2 on venous tone in conscious rats. | Naunyn-Schmiedeberg's archives of pharmacology 20060801 |
| Effects of proadrenomedullin N-terminal 20 peptide on the rat pituitary-adrenocortical axis under basal and stressful conditions. | International journal of molecular medicine 20060801 |
| The vasorelaxant effect of adrenomedullin, proadrenomedullin N-terminal 20 peptide and amylin in human skin. | Basic & clinical pharmacology & toxicology 20060801 |
| Study on increasing expression of adrenomedullin in diabetic rats' retinal pigment epithelium cells. | Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060801 |
| The gene expression of adrenomedullin, calcitonin-receptor-like receptor and receptor activity modifying proteins (RAMPs) in CCl4-induced rat liver cirrhosis. | Regulatory peptides 20060715 |
| Molecular evolution of proadrenomedullin N-terminal 20 peptide (PAMP): evidence for gene co-option. | Endocrinology 20060701 |
| Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. | British journal of pharmacology 20060701 |
| Adrenomedullin inhibits insulin exocytosis via pertussis toxin-sensitive G protein-coupled mechanism. | American journal of physiology. Endocrinology and metabolism 20060701 |
| Markers for sepsis diagnosis: what is useful? | Critical care clinics 20060701 |
| [Circulatory vasoactive substances and pathophysiology of hypertension]. | Nihon rinsho. Japanese journal of clinical medicine 20060701 |
| [EDRF]. | Nihon rinsho. Japanese journal of clinical medicine 20060701 |
| [Failing heart of Dahl rat]. | Nihon rinsho. Japanese journal of clinical medicine 20060701 |
| Effect of adrenomedullin on the activity of barosensitive neurons in the rostral ventrolateral medulla of rats. | Sheng li xue bao : [Acta physiologica Sinica] 20060625 |
| Peripheral adrenomedullin inhibits gastric emptying through CGRP8-37 -sensitive receptors and prostaglandins pathways in rats. | Peptides 20060601 |
| Pharmacology of the human CGRP1 receptor in Cos 7 cells. | Peptides 20060601 |
| Identification of adipocyte differentiation-related regulatory element for adrenomedullin gene repression (ADRE-AR) in 3T3-L1 cells. | Peptides 20060601 |
| Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease. | Gut 20060601 |
| Intermedin/adrenomedullin-2 dilates the rat pulmonary vascular bed: dependence on CGRP receptors and nitric oxide release. | Peptides 20060601 |
| Endothelium-independent relaxation by adrenomedullin in pregnant rat mesenteric artery: role of cAMP-dependent protein kinase A and calcium-activated potassium channels. | The Journal of pharmacology and experimental therapeutics 20060601 |
| Endothelin antagonism prevents diabetic retinopathy in NOD mice: a potential role of the angiogenic factor adrenomedullin. | Experimental biology and medicine (Maywood, N.J.) 20060601 |
| Physiological significance and therapeutic potential of adrenomedullin in pulmonary hypertension. | Cardiovascular & hematological disorders drug targets 20060601 |
| Effect of 6-week endurance training on hemodynamic and neurohormonal responses to lower body negative pressure (LBNP) in healthy young men. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060601 |
| Mitochondrial regulation of hypoxia-induced increase of adrenomedullin mRNA in HL-1 cells. | Biochemical and biophysical research communications 20060512 |
| Gs and Gi coupling of adrenomedullin in adult rat ventricular myocytes. | American journal of physiology. Heart and circulatory physiology 20060501 |
| Potentiated response to adrenomedullin in myocardia and aortas in spontaneously hypertensive rat. | Basic research in cardiology 20060501 |
| Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate: a role for protein kinase A. | British journal of pharmacology 20060501 |
| Identification and localization of adrenomedullin-storing cardiac mast cells. | International journal of molecular medicine 20060501 |
| A critical role for adrenomedullin-calcitonin receptor-like receptor in regulating rheumatoid fibroblast-like synoviocyte apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20060501 |
| Local regulator adrenomedullin contributes to the circulatory disturbance in cirrhotic rats. | World journal of gastroenterology 20060407 |
| Scar myofibroblasts of the infarcted rat heart express natriuretic peptides. | Journal of cellular physiology 20060401 |
| Hemodynamic, hormonal, and renal actions of adrenomedullin-2 in normal conscious sheep. | Endocrinology 20060401 |
| Adrenomedullin and elements of orthostatic competence after 41 h of voluntary submersion in water as measured in four healthy males. | European journal of applied physiology 20060401 |
| Source of plasma adrenomedullin in a patient with pheochromocytoma receiving hemodialysis. | International journal of urology : official journal of the Japanese Urological Association 20060401 |
| Intermedin1-53 activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas. | Biochemical and biophysical research communications 20060310 |
| NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth. | Biopolymers 20060301 |
| Adrenomedullin regulates cellular glutathione content via modulation of gamma-glutamate-cysteine ligase catalytic subunit expression. | Endocrinology 20060301 |
| Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor system following blood pressure reduction in nitric oxide-deficient hypertension. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Peptide hormones and lung cancer. | Panminerva medica 20060301 |
| Upregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in rats. | American journal of physiology. Heart and circulatory physiology 20060201 |
| Intermedin/Adrenomedullin-2 inhibits growth hormone release from cultured, primary anterior pituitary cells. | Endocrinology 20060201 |
| Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis. | Experimental neurology 20060201 |
| Adrenomedullin and tumour angiogenesis. | British journal of cancer 20060116 |
| Adrenomedullin inhibits angiotensin II-induced contraction in human aortic smooth muscle cells. | Regulatory peptides 20060115 |
| Adrenomedullin prevents apoptosis in prostate cancer cells. | Regulatory peptides 20060115 |
| Female sex steroids increase adrenomedullin-induced vasodilation by increasing the expression of adrenomedullin2 receptor components in rat mesenteric artery. | Endocrinology 20060101 |
| Hypoxic stress-enhanced expression and release of adrenomedullin (AM) and up-regulated AM receptors, while glucose starvation reduced AM expression and release and down-regulated AM receptors in monkey renal cells. | Physiological research 20060101 |
| Natriuretic peptide and adrenomedullin levels in chronic renal failure and effects of peritoneal dialysis. | Kidney international 20060101 |
| Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis. | The American journal of pathology 20060101 |
| The effect of vitamin E, L-arginine, N-nitro L-arginine methyl ester and forskolin on endocrine and metabolic changes of rats exposed to acute cold stress. | Saudi medical journal 20060101 |
| Increased production of adrenomedullin in glomeruli from anti-glomerular basement membrane glomerulonephritis rats treated with methylprednisolone. | Nephron. Experimental nephrology 20060101 |
| Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]. | Critical care (London, England) 20060101 |
| Cardiac diastolic dysfunction in renal-transplant recipients is associated with increased circulating Adrenomedullin. | Clinical transplantation 20060101 |
| A role for adrenomedullin in the pathogenesis of alveolar edema. | Critical care (London, England) 20060101 |
| The effects of anticancer drugs on levels of nitric oxide and adrenomedullin. | The Turkish journal of pediatrics 20060101 |
| Hypertension induced by nitric oxide synthase inhibitor increases responsiveness of ventricular myocardium and aorta of rat tissue to adrenomedullin stimulation in vitro. | Life sciences 20051212 |
| Effect of adrenomedullin administration on acetic acid-induced colitis in rats. | Peptides 20051201 |
| Renoprotective effect of long-term combined treatment with adrenomedullin and omapatrilat in hypertensive rats. | Journal of hypertension 20051201 |
| Mechanism of adrenomedullin-induced prolactin release from human prolactin-releasing adenoma cells. | Endocrine journal 20051201 |
| The ACAT inhibitor VULM1457 significantly reduced production and secretion of adrenomedullin (AM) and down-regulated AM receptors on human hepatoblastic cells. | General physiology and biophysics 20051201 |
| Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse. | Developmental biology 20051115 |
| Adrenomedullin release in the rat mesenteric resistance artery. | Peptides 20051101 |
| Centrally administered adrenomedullin 2 activates hypothalamic oxytocin-secreting neurons, causing elevated plasma oxytocin level in rats. | American journal of physiology. Endocrinology and metabolism 20051101 |
| Intermedin functions as a pituitary paracrine factor regulating prolactin release. | Molecular endocrinology (Baltimore, Md.) 20051101 |
| Effect of adrenomedullin on adrenergic vasoconstriction in mesenteric resistance arteries of the rat. | Journal of pharmacological sciences 20051101 |
| PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. | Neuron 20051020 |
| Measurement of midregional proadrenomedullin in plasma with an immunoluminometric assay. | Clinical chemistry 20051001 |
| Adrenomedullin causes coronary vasodilation in humans: effects of inhibition of nitric oxide synthesis. | Journal of cardiovascular pharmacology 20051001 |
| Plasma and urinary adrenomedullin levels in children with acute pyelonephritis. | Nephrology (Carlton, Vic.) 20051001 |
| Adrenomedullin is up-regulated in nitrofen-induced fetal pulmonary hypoplasia. | Journal of pediatric surgery 20051001 |
| Ether stress increases adrenomedullin gene expression and levels in the rat adrenal. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001 |
| Adrenomedullin limits reperfusion injury in experimental myocardial infarction. | Basic research in cardiology 20050901 |
| Molecular profile of androgen-independent prostate cancer xenograft LuCaP 23.1. | The Journal of steroid biochemistry and molecular biology 20050901 |
| Influence of misoprostol (PGE1) on amniotic fluid and maternal serum adrenomedullin levels. | Acta obstetricia et gynecologica Scandinavica 20050901 |
| Adrenomedullin reduces mesangial cell number and glomerular inflammation in experimental mesangioproliferative glomerulonephritis. | Kidney international 20050901 |
| Adrenomedullin reflects cardiac dysfunction, excessive blood volume, and inflammation in hemodialysis patients. | Kidney international 20050901 |
| Cardiovascular effects of newly discovered peptide intermedin/adrenomedullin 2. | Peptides 20050901 |
| [Dynamic changes in plasma adrenomedullin levels and effect of enalapril intervention in diabetic rats]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050901 |
| Adrenomedullin modulates COX-2 and HGF expression in reserpine-injuried gastric mucosa in the rat. | European journal of pharmacology 20050822 |
| Study on the signalling pathway of inhibitory effect of adreno-medullin on the growth of cultured glomerular mesangial cells. | Chinese medical journal 20050820 |
| Plasma and urinary adrenomedullin levels in children with renal parenchymal scar and vesicoureteral reflux. | Pediatric nephrology (Berlin, Germany) 20050801 |
| Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions. | Clinical and experimental pharmacology & physiology 20050801 |
| Adrenomedullin(27-52) inhibits vascular calcification in rats. | Regulatory peptides 20050715 |
| Effect of adrenomedullin and proadrenomedullin N-terminal 20 peptide on sugar transport in the rat intestine. | Regulatory peptides 20050715 |
| Adrenomedullin induces heme oxygenase-1 gene expression and cGMP formation in rat vascular smooth muscle cells. | Peptides 20050701 |
| Mechanisms responsible for vascular hyporesponsiveness to adrenomedullin after hemorrhage: the central role of adrenomedullin binding protein-1. | Annals of surgery 20050701 |
| Adrenomedullin reduces intracellular calcium concentration in cultured hippocampal neurons. | Sheng li xue bao : [Acta physiologica Sinica] 20050625 |
| Effects of adrenomedullin gene overexpression on biological behavior of hepatic stellate cells. | World journal of gastroenterology 20050621 |
| Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin. | Journal of medicinal chemistry 20050616 |
| Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue. | Endocrinology 20050601 |
| The vasoactive peptide adrenomedullin is secreted by adipocytes and inhibits lipolysis through NO-mediated beta-adrenergic agonist oxidation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601 |
| Sympatho-inhibitory action of endogenous adrenomedullin through inhibition of oxidative stress in the brain. | Hypertension (Dallas, Tex. : 1979) 20050601 |
| Presence and function of the calcitonin gene-related peptide receptor on rat pial arteries investigated in vitro and in vivo. | Cephalalgia : an international journal of headache 20050601 |
| The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation. | Cancer research 20050601 |
| Hemodynamic and neuroendocrine predictors of lower body negative pressure (LBNP) intolerance in healthy young men. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050601 |
| Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides. | Biochemical and biophysical research communications 20050520 |
| Brain-derived adrenomedullin controls blood volume through the regulation of arginine vasopressin production and release. | American journal of physiology. Regulatory, integrative and comparative physiology 20050501 |
| Adrenomedullin stimulates nitric oxide release from SK-N-SH human neuroblastoma cells by modulating intracellular calcium mobilization. | Endocrinology 20050501 |
| Visualisation of morphological changes in living intact human microvessels using confocal microscopy. | Microvascular research 20050501 |
| Angiotensin II stimulates cardiac adrenomedullin production and causes accumulation of mature adrenomedullin independently of hemodynamic stress in vivo. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050501 |
| [Effect of intracerebroventricular injection of adrenomedullin on catecholaminergic neurons and expression of c-fos in the rat brain nuclei involved in cardiovascular regulation]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050501 |
| A novel immunosuppressant FTY720 ameliorates proteinuria and alterations of intrarenal adrenomedullin in rats with autoimmune glomerulonephritis. | Regulatory peptides 20050415 |
| Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats. | American journal of physiology. Heart and circulatory physiology 20050401 |
| Human adrenomedullin gene silencing by short interfering RNAs: a preliminary study. | International journal of molecular medicine 20050401 |
| Protective effects of intermedin/adrenomedullin2 on ischemia/reperfusion injury in isolated rat hearts. | Peptides 20050301 |
| Endothelin-1 and adrenomedullin enhance the growth of human adrenocortical carcinoma-derived SW-13 cell line by stimulating proliferation and inhibiting apoptosis. | International journal of molecular medicine 20050301 |
| Haplotype-based case-control study revealing an association between the adrenomedullin gene and proteinuria in subjects with essential hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20050301 |
| Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage. | Critical care medicine 20050201 |
| Vasoactive mediators and retinopathy during type 1 diabetic pregnancy. | Acta ophthalmologica Scandinavica 20050201 |
| Adrenomedullin inhibits angiotensin II-induced oxidative stress and gene expression in rat endothelial cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20050201 |
| Alteration of renal adrenomedullin and its receptor system in the severely hypertensive rat: effect of diuretic. | Regulatory peptides 20050115 |
| Adrenomedullin is highly expressed in blood monocytes associated with acute Kawasaki disease: a microarray gene expression study. | Pediatric research 20050101 |
| Plasma levels of adrenomedullin in patients with adrenoleukodystrophy/adrenomyeloneuropathy. | Hormone research 20050101 |
| Adrenomedullin and leptin levels in diabetic retinopathy and retinal diseases. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101 |
| Neurohormonal changes in medical students during academic stress. | Annals of Saudi medicine 20050101 |
| High plasma levels of human chromogranin A and adrenomedullin in patients with pheochromocytoma. | Tumori 20050101 |
| Levels of plasma total adrenomedullin are related with two acute phase inflammatory reactants (fibrinogen and sialic acid) but not with markers of endothelial dysfunction in Type 1 diabetes Adrenomedullin and vascular risk factors in Type 1 DM. | Journal of diabetes and its complications 20050101 |
| [Upregulation of adrenomedullin system in left ventricular hypertrophy of severe hypertension rats]. | Zhonghua xin xue guan bing za zhi 20050101 |
| Antimicrobial peptides in human skin. | Chemical immunology and allergy 20050101 |
| New methods for researching accessory proteins. | Journal of molecular neuroscience : MN 20050101 |
| Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study. | Critical care (London, England) 20050101 |
| Significant changes of peripheral perfusion and plasma adrenomedullin levels in N-acetylcysteine long term treatment of patients with sclerodermic Raynauds phenomenon. | International journal of immunopathology and pharmacology 20050101 |
| Adrenomedullin induces matrix metalloproteinase-2 activity in rat aortic adventitial fibroblasts. | Biochemical and biophysical research communications 20041203 |
| Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease. | Experimental and molecular pathology 20041201 |
| Malfunction of vascular control in lifestyle-related diseases: distribution of adrenomedullin-containing perivascular nerves and its alteration in hypertension. | Journal of pharmacological sciences 20041201 |
| Adrenomedullin gene delivery protects against cerebral ischemic injury by promoting astrocyte migration and survival. | Human gene therapy 20041201 |
| Effects of adrenomedullin on aldosterone-induced cell proliferation in rat cardiac fibroblasts. | Biochimica et biophysica acta 20041105 |
| Adrenomedullin antagonist treatment during early gestation in rats causes fetoplacental growth restriction through apoptosis. | Biology of reproduction 20041101 |
| A possible mechanism for the action of adrenomedullin in brain to stimulate stress hormone secretion. | Endocrinology 20041101 |
| Heterodimers and family-B GPCRs: RAMPs, CGRP and adrenomedullin. | Biochemical Society transactions 20041101 |
| Biological importance of the peptides of the calcitonin family as revealed by disruption and transfer of corresponding genes. | Peptides 20041101 |
| Evaluation of neurohumoral activation (adrenomedullin, BNP, catecholamines, etc.) in patients with acute myocardial infarction. | Internal medicine (Tokyo, Japan) 20041101 |
| Fasting-induced down-regulation of NADPH-diaphorase in the magnocellular PVN of rats. | Yonsei medical journal 20041031 |
| Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: roles of glutamate and nitric oxide. | American journal of physiology. Regulatory, integrative and comparative physiology 20041001 |
| Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone. | Journal of hypertension 20041001 |
| Intermedin, a novel calcitonin family peptide that exists in teleosts as well as in mammals: a comparison with other calcitonin/intermedin family peptides in vertebrates. | Peptides 20041001 |
| Effects of adrenomedullin on cell proliferation in rat adventitia induced by lysophosphatidic acid. | Regulatory peptides 20040915 |
| Characterization of adrenomedullin in non-human primates. | Biochemical and biophysical research communications 20040903 |
| Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1. | American journal of physiology. Regulatory, integrative and comparative physiology 20040901 |
| [PAMP: novel hypotensive peptide derived from adrenomedullin precursor]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
| [Protective effects of antioxidants against cardiovascular damage]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
| [The adrenomedullin family and sympathoadrenal system]. | Nihon rinsho. Japanese journal of clinical medicine 20040901 |
| [Adrenomedullin--the link between the sympathetic nervous system activation and peripheral vasodilatation in some patients with vasovagal syncope]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20040901 |
| Estrogen and phytoestrogen regulate the mRNA expression of adrenomedullin and adrenomedullin receptor components in the rat uterus. | Molecular and cellular endocrinology 20040831 |
| Angiotensin II-induced insulin resistance is enhanced in adrenomedullin-deficient mice. | Endocrinology 20040801 |
| The calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS blocks CGRP and adrenomedullin vasoactive responses in the microvasculature. | British journal of pharmacology 20040801 |
| Hemodynamic and hormonal actions of adrenomedullin. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040801 |
| Adrenomedullin as a sensitive marker for coronary and peripheral arterial complications in patients with atherosclerotic risks. | Peptides 20040801 |
| [Adrenomedullin enhances glucose toxicity to pancreatic beta-cell of islets from spontaneously hypertensive rat (SHR)]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20040801 |
| Adrenomedullin administration immediately after myocardial infarction ameliorates progression of heart failure in rats. | Circulation 20040727 |
| Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. | Circulation research 20040723 |
| Aspartate(69) of the calcitonin-like receptor is required for its functional expression together with receptor-activity-modifying proteins 1 and -2. | Biochemical and biophysical research communications 20040709 |
| Antioxidant effect of adrenomedullin on angiotensin II-induced reactive oxygen species generation in vascular smooth muscle cells. | Endocrinology 20040701 |
| Vascular actions of calcitonin gene-related peptide and adrenomedullin. | Physiological reviews 20040701 |
| Adrenomedullin contributes to vascular hyporeactivity in cirrhotic rats with ascites via a release of nitric oxide. | Scandinavian journal of gastroenterology 20040701 |
| Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA. | Regulatory peptides 20040615 |
| Adrenomedullin modulates hemodynamic and cardiac effects of angiotensin II in conscious rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20040601 |
| Cardiac gene expression of natriuretic substances is altered in streptozotocin-induced diabetes during angiotensin II-induced pressure overload. | Journal of hypertension 20040601 |
| Comparative study of the inhibitory effects of adrenomedullin on angiotensin II contraction in rat conductance and resistance arteries. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20040601 |
| Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1. | Biochemical and biophysical research communications 20040521 |
| Relationship between contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of rats in septic shock. | Regulatory peptides 20040515 |
| Adrenomedullin can protect against pulmonary vascular remodeling induced by hypoxia. | Circulation 20040511 |
| Selective inactivation of adrenomedullin over calcitonin gene-related peptide receptor function by the deletion of amino acids 14-20 of the mouse calcitonin-like receptor. | The Journal of biological chemistry 20040507 |
| Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior. | Experimental cell research 20040501 |
| Adrenomedullin affects two signal transduction pathways and the migration in retinal pigment epithelial cells. | Investigative ophthalmology & visual science 20040501 |
| Adrenomedullin: its role in the cardiovascular system. | Seminars in vascular medicine 20040501 |
| Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage. | Circulation 20040413 |
| Mycophenolate mofetil prevents autoimmune glomerulonephritis and alterations of intrarenal adrenomedullin in rats. | European journal of pharmacology 20040405 |
| Up-regulation of the adrenomedullin system mediates hypotension and hypoaldosteronism induced by simulated microgravity. | International journal of molecular medicine 20040401 |
| Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle. | BJU international 20040401 |
| Distribution of adrenomedullin-containing perivascular nerves in the rat mesenteric artery. | Peptides 20040401 |
| The role of adrenomedullin and its receptor system in cardiovascular calcification of rat induced by Vitamin D(3) plus nicotine. | Peptides 20040401 |
| Disassociated increases of adrenomedullin in the rat cerebrospinal fluid and plasma after salt loading and systemic administration of lipopolysaccharide. | Peptides 20040401 |
| Cell therapy for pulmonary hypertension: what is the true potential of endothelial progenitor cells? | Circulation 20040330 |
| Endogenous adrenomedullin protects against vascular response to injury in mice. | Circulation 20040309 |
| Role of cyclooxygenase in ventricular effects of adrenomedullin: is adrenomedullin a double-edged sword in sepsis? | American journal of physiology. Heart and circulatory physiology 20040301 |
| Effects of C-reactive protein on atherogenic mediators and adrenomedullin in human coronary artery endothelial and smooth muscle cells. | Biochemical and biophysical research communications 20040220 |
| Stimulation of adhesion molecule expression in human endothelial cells (HUVEC) by adrenomedullin and corticotrophin. | American journal of physiology. Cell physiology 20040201 |
| The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats. | Kidney international 20040201 |
| Influence of adrenomedullin on tone of isolated bovine retinal arteries. | Investigative ophthalmology & visual science 20040201 |
| Adrenomedullin infusion attenuates myocardial ischemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway. | Circulation 20040120 |
| The inhibitory effect of adrenomedullin in the rat ileum: cross-talk with beta3-adrenoceptor in the serotonin-induced muscle contraction. | The Journal of pharmacology and experimental therapeutics 20040101 |
| Development of an ultrasensitive enzyme immunoassay for human proadrenomedullin N-terminal 20 peptide and direct measurement of two molecular forms of PAMP in plasma from healthy subjects and patients with cardiovascular disease. | Clinical biochemistry 20040101 |
| The assessment of vasoactive properties of CGRP and adrenomedullin in the microvasculature: a study using in vivo and in vitro assays in the mouse. | Journal of molecular neuroscience : MN 20040101 |
| Congenital unilateral ureteropelvic junction obstruction of the rat: a useful animal model for human ureteropelvic junction obstruction? | Urology 20040101 |
| Neuropeptides and gastric mucosal homeostasis. | Current topics in medicinal chemistry 20040101 |
| Adrenomedullin levels in early and late rhegmatogenous retinal detachments. | Japanese journal of ophthalmology 20040101 |
| Alternatives to nitric oxide. | British medical bulletin 20040101 |
| Three receptor-activity-modifying proteins define calcitonin gene-related peptide or adrenomedullin selectivity of the mouse calcitonin-like receptor in COS-7 cells. | Biochemical pharmacology 20031201 |
| Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide. | British journal of pharmacology 20031201 |
| Steroids and adrenomedullin growth patterns in human ovarian cancer cells: estrogenic-regulation assay. | Gynecologic oncology 20031201 |
| Impact of nitric oxide on adrenomedullin- and proadrenomedullin N-terminal 20 peptide-induced cardiac responses: action by alone and combined administration. | Peptides 20031201 |
| Adrenomedullin and endocrine disorders. | Panminerva medica 20031201 |
| Identification of a novel adrenomedullin gene family in teleost fish. | Biochemical and biophysical research communications 20031128 |
| Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer. | British journal of cancer 20031117 |
| Role of brain dopaminergic system in the adrenomedullin-induced diuresis and natriuresis. | Pharmacological research 20031101 |
| Repeated inhalation of adrenomedullin ameliorates pulmonary hypertension and survival in monocrotaline rats. | American journal of physiology. Heart and circulatory physiology 20031101 |
| Involvement of calcitonin gene-related peptide in elevation of skin temperature in castrated male rats. | Urology 20031101 |
| Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. | American journal of physiology. Heart and circulatory physiology 20031001 |
| Angiogenic role of adrenomedullin through activation of Akt, mitogen-activated protein kinase, and focal adhesion kinase in endothelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001 |
| CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS. | British journal of pharmacology 20031001 |
| The effect of adrenomedullin (ADM) on tyrosine hydroxylase (TH) enzyme activity and blood pressure in cold exposed rats. | Endocrine journal 20031001 |
| [Effects of adrenomedullin on secretory function of pancreatic islet in spontaneously hypertensive rat in vitro]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20031001 |
| N-Glycosylation and conserved cysteine residues in RAMP3 play a critical role for the functional expression of CRLR/RAMP3 adrenomedullin receptor. | Biochemistry 20030902 |
| Chronic salt loading upregulates expression of adrenomedullin and its receptors in adrenal glands and kidneys of the rat. | Hypertension (Dallas, Tex. : 1979) 20030901 |
| Adrenomedullin-induced endothelium-dependent relaxation in porcine ciliary arteries. | Investigative ophthalmology & visual science 20030901 |
| Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha. | European journal of endocrinology 20030901 |
| Accelerated cardiac hypertrophy and renal damage induced by angiotensin II in adrenomedullin knockout mice. | Hypertension research : official journal of the Japanese Society of Hypertension 20030901 |
| Two selective rat adrenomedullin (AM)-receptor antagonists: AM20-50 and AM24-50. | Cellular and molecular biology (Noisy-le-Grand, France) 20030901 |
| Effect of intracarotid administration of adrenomedullin on the spontaneous electrical activity of area postrema neurons in sino-aortic denervated rats. | Sheng li xue bao : [Acta physiologica Sinica] 20030825 |
| Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells. | Circulation 20030819 |
| Evaluation of adrenomedullin levels in renal parenchyma subjected to extracorporeal shockwave lithotripsy. | Urological research 20030801 |
| Secretory and vascular effects of adrenomedullin in gastric ulcer: role of CGRP- and adrenomedullin-receptors. | Peptides 20030801 |
| Effects of adrenomedullin, C-type natriuretic peptide, and parathyroid hormone-related peptide on calcification in cultured rat vascular smooth muscle cells. | Journal of cardiovascular pharmacology 20030701 |
| Adrenomedullin upregulates M2-muscarinic receptors in cardiomyocytes from P19 cell line. | British journal of pharmacology 20030701 |
| Suppression of cytokine-induced expression of adrenomedullin and endothelin-1 by dexamethasone in T98G human glioblastoma cells. | Peptides 20030701 |
| Identification of the human receptor activity-modifying protein 1 domains responsible for agonist binding specificity. | The Journal of biological chemistry 20030620 |
| Circulating adrenomedullin is increased in relation with increased creatinine and atrial natriuretic peptide in liver-transplant recipients. | Regulatory peptides 20030615 |
| Microsatellite DNA polymorphism of human adrenomedullin gene in type 2 diabetic patients with renal failure. | Kidney international 20030601 |
| Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta. | Journal of cardiovascular pharmacology 20030601 |
| Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. | Journal of hypertension 20030601 |
| Plasma adrenomedullin response to maximal exercise in healthy subjects. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030601 |
| Glycine-extended adrenomedullin exerts vasodilator effect through amidation in the rat aorta. | Regulatory peptides 20030515 |
| Deficiency of adrenomedullin induces insulin resistance by increasing oxidative stress. | Hypertension (Dallas, Tex. : 1979) 20030501 |
| Effects of adrenomedullin and its fragment 22-52 on basal and ACTH-stimulated secretion of cultured rat adrenocortical cells. | International journal of molecular medicine 20030501 |
| The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha. | European journal of biochemistry 20030501 |
| Paracrine effects of PAMP and adrenomedullin on the human adrenal H295R cell line: PAMP but not adrenomedullin stimulates DHEA secretion. | Regulatory peptides 20030415 |
| Autonomic and neuroendocrine actions of adrenomedullin in the brain: mechanisms for homeostasis. | Regulatory peptides 20030415 |
| Adrenomedullin and the renin-angiotensin-aldosterone system. | Regulatory peptides 20030415 |
| Adrenomedullin and heart failure. | Regulatory peptides 20030415 |
| Regulation of production and secretion of adrenomedullin in the cardiovascular system. | Regulatory peptides 20030415 |
| Altered gene expression of adrenomedullin and its receptor system and molecular forms of tissue adrenomedullin in left ventricular hypertrophy induced by malignant hypertension. | Regulatory peptides 20030415 |
| Involvement of the central adrenomedullin peptides in the baroreflex. | Regulatory peptides 20030415 |
| Adrenomedullin in the eye. | Regulatory peptides 20030415 |
| Regulation of pancreatic physiology by adrenomedullin and its binding protein. | Regulatory peptides 20030415 |
| Adrenomedullin inhibits angiotensin AT1A receptor expression and function in cardiac fibroblasts. | Regulatory peptides 20030415 |
| Mechanisms regulating adrenomedullin gene expression in the left ventricle: role of mechanical load. | Regulatory peptides 20030415 |
| Ventricular adrenomedullin is associated with myocyte hypertrophy in human transplanted heart. | Regulatory peptides 20030415 |
| Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells. | Regulatory peptides 20030415 |
| Effects of levonorgestrel-releasing intra-uterine system on the expression of vascular endothelial growth factor and adrenomedullin in the endometrium in adenomyosis. | Human reproduction (Oxford, England) 20030401 |
| Paradoxically abundant expression of Bcl-2 and adrenomedullin in invasive cervical squamous carcinoma. | International journal of clinical oncology 20030401 |
| Roles of different peptide fragments derived from proadrenomedullin in the regulation of vascular tone in isolated rat aorta. | Peptides 20030401 |
| [Neurohumoral mechanisms for vasovagal syncopes. Part I]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401 |
| Expression of adrenomedullin and its receptor by chondrocyte phenotype cells. | Biochemical and biophysical research communications 20030328 |
| Lack of adrenomedullin on antigen-induced bronchoconstriction in guinea pigs in vivo. | Life sciences 20030314 |
| Pathophysiological role of nitric oxide and adrenomedullin in autism. | Cell biochemistry and function 20030301 |
| Interactions between neural and hormonal mediators of renal vascular tone in anaesthetized rabbits. | Experimental physiology 20030301 |
| Ventricular adrenomedullin system in the transition from LVH to heart failure in rats. | Hypertension (Dallas, Tex. : 1979) 20030301 |
| Changes of adrenomedullin and receptor activity modifying protein 2 (RAMP2) in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia. | Peptides 20030301 |
| Adrenomedullin stimulates somatostatin and thus inhibits histamine and acid secretion in the fundus of the stomach. | Regulatory peptides 20030227 |
| Responses to human CGRP, ADM, and PAMP in human thymic arteries. | American journal of physiology. Regulatory, integrative and comparative physiology 20030201 |
| Specificity of porcine calcitonin receptor and calcitonin receptor-like receptor in the presence of receptor-activity-modifying proteins. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Direct measurement of glycine-extended adrenomedullin in plasma and tissue using an ultrasensitive immune complex transfer enzyme immunoassay in rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Mapping of the adrenomedullin-binding domains in human complement factor H. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Adrenomedullin, an autocrine mediator of blood-brain barrier function. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Pathophysiological function of adrenomedullin and proadrenomedullin N-terminal peptides in adrenal chromaffin cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Endothelial responses of the aorta from adrenomedullin transgenic mice and knockout mice. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Role of the endogenous adrenomedullin system in regulating the secretion and growth of rat adrenal cortex. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Adrenomedullin promotes proliferation and migration of cultured endothelial cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Variations of human adrenomedullin gene and its relation to cardiovascular diseases. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Pulmonary vasodilator response to adrenomedullin in patients with pulmonary hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20030201 |
| Effects of long and short hemodialysis on endothelial function: a short-term study. | Kidney international 20030201 |
| Changes in amount of ADM mRNA and RAMP2 mRNA in calcified vascular smooth muscle cells. | Peptides 20030201 |
| [Change of the expression of adrenomedullin in lung and effect on contraction of isolated tracheal strip of asthmatic guinea pigs]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030201 |
| Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Adrenomedullin expression and function in the rat carotid body. | The Journal of endocrinology 20030101 |
| Relationship between adrenomedullin and vasopressin-aquaporin system under general anesthesia. | Hormone research 20030101 |
| Elevated adrenomedullin in the vitreous of patients with diabetic retinopathy. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101 |
| Effects of adrenomedullin on the contraction of gastric arteries during reserpine-induced gastric ulcer. | Peptides 20030101 |
| Relaxation effects of adrenomedullin in carbachol-precontracted rabbit internal anal sphincter. | Journal of gastroenterology 20030101 |
| The effect of adrenomedullin, amylin fragment 8-37 and calcitonin gene-related peptide on contractile force, heart rate and coronary perfusion pressure in isolated rat hearts. | Acta physiologica Hungarica 20030101 |
| Gender differences in pulmonary arterial reactivity to dilatory agonists in pulmonary hypertension. | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20030101 |
| Regulation of adrenomedullin signaling in kidney interstitial fibroblasts. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101 |
| Adrenomedullin inhibits pressure-induced mesangial MCP-1 expression through activation of protein kinase A. | Journal of nephrology 20030101 |
| Microinjection of adrenomedullin into rostral ventrolateral medulla increases blood pressure, heart rate and renal sympathetic nerve activity in rats. | Sheng li xue bao : [Acta physiologica Sinica] 20021225 |
| Protective effect of adrenomedullin in mannitol-induced apoptosis. | Apoptosis : an international journal on programmed cell death 20021201 |
| Adrenomedullin improves cardiac function and prevents renal damage in streptozotocin-induced diabetic rats. | American journal of physiology. Endocrinology and metabolism 20021201 |
| Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin-binding protein-1 in sepsis: down-regulation of proinflammatory cytokines. | Critical care medicine 20021201 |
| Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1. | Annals of surgery 20021101 |
| Long-term adrenomedullin administration in experimental heart failure. | Hypertension (Dallas, Tex. : 1979) 20021101 |
| Source of plasma adrenomedullin in patients with pheochromocytoma. | American journal of hypertension 20021101 |
| Adrenomedullin gene expression in human placental tIssue and leukocytes: a potential marker of severe tIssue hypoxia in neonates with birth asphyxia. | European journal of endocrinology 20021101 |
| Bacterial lipopolysaccharide directly stimulates cortisol secretion in human adrenal cells. | Endocrine research 20021101 |
| Calcitonin gene-related peptide and adrenomedullin release in humans: effects of exercise and hypoxia. | Regulatory peptides 20021015 |
| Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis. | Blood 20021015 |
| Sequencing of a calcitonin receptor-like receptor in salmon Oncorhynchus gorbuscha. Functional studies using the human receptor activity-modifying proteins. | Gene 20021002 |
| Simulated microgravity impairs aldosterone secretion in rats: possible involvement of adrenomedullin. | American journal of physiology. Regulatory, integrative and comparative physiology 20021001 |
| Evidence for an autocrine-paracrine role of adrenomedullin in the cultured rat adrenal zona glomerulosa cells. | International journal of molecular medicine 20021001 |
| Vasoactive and natriuretic mediators in umbilical cord blood: a report of our observation and review of the literature. | Early human development 20021001 |
| Mature form of adrenomedullin is a useful marker to evaluate blood volume in hemodialysis patients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20021001 |
| Hemodynamic and humoral effects of vasopeptidase inhibition in canine hypertension. | Hypertension (Dallas, Tex. : 1979) 20021001 |
| Effects of endothelin-1 on release of adrenomedullin and C-type natriuretic peptide from individual human vascular endothelial cells. | The Journal of endocrinology 20021001 |
| Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. | Circulation research 20020906 |
| Adrenomedullin inhibits doxorubicin-induced cultured rat cardiac myocyte apoptosis via a cAMP-dependent mechanism. | Endocrinology 20020901 |
| [Changes in plasma levels of adrenomedullin and cyclic adenosine monophosphate and their interrelation in patients with chronic heart failure]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020901 |
| The localization of adrenomedullin in rat kidney tissue and its inhibitory effect on the growth of cultured rat mesangial cells. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20020901 |
| Adrenomedullin over-expression in the caudate-putamen of the adult rat brain after ischaemia-reperfusion injury. | Neuroscience letters 20020830 |
| The calcitonin receptor-like receptor/receptor activity-modifying protein 1 heterodimer can function as a calcitonin gene-related peptide-(8-37)-sensitive adrenomedullin receptor. | European journal of pharmacology 20020830 |
| cAMP signal transduction, a potential compensatory pathway for coronary endothelial NO production after heart failure. | Arteriosclerosis, thrombosis, and vascular biology 20020801 |
| Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression. | Arteriosclerosis, thrombosis, and vascular biology 20020801 |
| Large-scale production of functional human adrenomedullin: expression, cleavage, amidation, and purification. | Protein expression and purification 20020801 |
| Adrenomedullin: receptor and signal transduction. | Biochemical Society transactions 20020801 |
| Follicular fluid adrenomedullin concentrations in spontaneous and stimulated cycles: relationship to ovarian function and endothelin-1 and nitric oxide. | Regulatory peptides 20020715 |
| Acute hyperinsulinemia is associated with increased circulating levels of adrenomedullin in patients with type 2 diabetes mellitus. | European journal of endocrinology 20020701 |
| Endothelial PAS domain protein 1 (EPAS1) induces adrenomedullin gene expression in cardiac myocytes: role of EPAS1 in an inflammatory response in cardiac myocytes. | Journal of molecular and cellular cardiology 20020701 |
| Long-term adrenomedullin infusion improves survival in malignant hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20020701 |
| Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. | Journal of hypertension 20020701 |
| [The other gastrointestinal hormones in diabetes mellitus]. | Nihon rinsho. Japanese journal of clinical medicine 20020701 |
| Effects of adrenomedullin on vascular calcification in rats. | Zeitschrift fur Kardiologie 20020701 |
| The adrenomedullin receptor acts as clearance receptor in pulmonary circulation. | Biochemical and biophysical research communications 20020607 |
| Novel regulation of adrenomedullin receptor by PDGF: role of receptor activity modifying protein-3. | American journal of physiology. Cell physiology 20020601 |
| Aldosterone-adrenomedullin: a new feedback regulation in blood vessels? | Journal of hypertension 20020601 |
| Aldosterone augments adrenomedullin production without stimulating pro-adrenomedullin N-terminal 20 peptide secretion in vascular smooth muscle cells. | Journal of hypertension 20020601 |
| Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure. | Clinical science (London, England : 1979) 20020601 |
| Renoprotective effect of chronic adrenomedullin infusion in Dahl salt-sensitive rats. | Hypertension (Dallas, Tex. : 1979) 20020601 |
| Urinary adrenomedullin levels are increased and correlated with plasma concentrations in patients with Behçet's syndrome. | International journal of urology : official journal of the Japanese Urological Association 20020601 |
| Effect of static handgrip on plasma adrenomedullin concentration in patients with heart failure and in healthy subjects. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601 |
| Gastroprotective effect of adrenomedullin administered subcutaneously in the rat. | Peptides 20020601 |
| Maternal nitric oxide supplementation increases adrenomedullin concentrations in growth retarded fetuses. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020601 |
| High plasma adrenomedullin concentrations in patients with high-renin essential hypertension. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20020601 |
| Role of endothelium-derived relaxing factors in adrenomedullin-induced vasodilation in the rat kidney. | European journal of pharmacology 20020524 |
| Effects of amylin-related peptides on food intake, meal patterns, and gastric emptying in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20020501 |
| [Regulation of brain microvessel function]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20020501 |
| Adrenomedullin promotes formation of xenografted endometrial tumors by stimulation of autocrine growth and angiogenesis. | Oncogene 20020425 |
| Adrenomedullin in the central nervous system. | Microscopy research and technique 20020415 |
| Adrenomedullin in the adrenal. | Microscopy research and technique 20020415 |
| Adrenomedullin and the integrative physiology of fluid and electrolyte balance. | Microscopy research and technique 20020415 |
| Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene. | Circulation research 20020405 |
| Functional interaction of G protein-coupled receptors of the adrenomedullin peptide family with accessory receptor-activity-modifying proteins (RAMP). | Microscopy research and technique 20020401 |
| Adrenomedullin modulates the neurohumoral response to acute volume loading in normal conscious sheep. | The Journal of endocrinology 20020401 |
| Rapid increase in cardiac adrenomedullin gene expression caused by acute pressure overload: effect of the renin-angiotensin system on gene expression. | Circulation journal : official journal of the Japanese Circulation Society 20020401 |
| Tamoxifen induction of angiogenic factor expression in endometrium. | British journal of cancer 20020304 |
| In-vivo angiogenesis and progestogens. | Human reproduction (Oxford, England) 20020301 |
| Adrenomedullin, calcitonin gene-related peptide and their receptors: evidence for a decreased placental mRNA content in preeclampsia and HELLP syndrome. | European journal of obstetrics, gynecology, and reproductive biology 20020210 |
| Differential actions of vasopeptidase inhibition versus angiotensin-converting enzyme inhibition on diuretic therapy in experimental congestive heart failure. | Circulation 20020205 |
| Possible involvement of oxidative stress in hypoxia-induced adrenomedullin secretion in cultured rat cardiomyocytes. | European journal of pharmacology 20020201 |
| Adrenomedullin expression in rat uterus is correlated with plasma estradiol. | American journal of physiology. Endocrinology and metabolism 20020101 |
| Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage. | Circulation 20020101 |
| Combined endopeptidase inhibition and adrenomedullin in sheep with experimental heart failure. | Hypertension (Dallas, Tex. : 1979) 20020101 |
| Inflammatory cytokines stimulate adrenomedullin expression through nitric oxide-dependent and -independent pathways. | Hypertension (Dallas, Tex. : 1979) 20020101 |
| Nitric oxide stimulates adrenomedullin secretion and gene expression in endothelial cells. | Pharmacology 20020101 |
| Possible role of nitric oxide and adrenomedullin in bipolar affective disorder. | Neuropsychobiology 20020101 |
| Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat. | Neuroscience 20020101 |
| The possible pathophysiological role of plasma nitric oxide and adrenomedullin in schizophrenia. | Journal of psychiatric research 20020101 |
| Differential induction of early response genes by adrenomedullin and transforming growth factor-beta1 in human lung cancer cells. | Anticancer research 20020101 |
| Amylin and adrenomedullin: novel regulators of bone growth. | Current pharmaceutical design 20020101 |
| Chronic hypotension in the dialysis patient. | Journal of nephrology 20020101 |
| Adrenomedullin: a cardiac depressant factor in septic shock. | Journal of cardiac surgery 20020101 |
| The seven amino acids of human RAMP2 (86) and RAMP3 (59) are critical for agonist binding to human adrenomedullin receptors. | The Journal of biological chemistry 20011228 |
| Effects of adrenomedullin on adrenocorticotropic hormone (ACTH) release in pituitary cell cultures and on ACTH and oxytocin responses to shaker stress in conscious rat. | Brain research 20011220 |
| Production of cAMP by adrenomedullin in human oligodendroglial cell line KG1C: comparison with calcitonin gene-related peptide and amylin. | Brain research. Molecular brain research 20011216 |
| Comparative actions of adrenomedullin and nitroprusside: interactions with ANG II and norepinephrine. | American journal of physiology. Regulatory, integrative and comparative physiology 20011201 |
| Role of increased circulating and renal adrenomedullin in rats with malignant hypertension. | American journal of physiology. Regulatory, integrative and comparative physiology 20011201 |
| Expression and function of adrenomedullin and its receptors in Conn's adenoma cells. | International journal of molecular medicine 20011201 |
| [New clinical laboratory tests for endocrine and metabolism disorders]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20011110 |
| Adrenomedullin augments the neurohumoral response to haemorrhage in non-pregnant but not in pregnant sheep. | The Journal of endocrinology 20011101 |
| [Effects of long-term treatment with prostacyclin on plasma adrenomedullin in patients with primary pulmonary hypertension]. | Journal of cardiology 20011101 |
| Intracerebroventricular adrenomedullin stimulates the hypothalamic-pituitary-adrenal axis, the sympathetic nervous system and production of hypothalamic nitric oxide. | Journal of neuroendocrinology 20011101 |
| A review of the biological properties and clinical implications of adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP), hypotensive and vasodilating peptides. | Peptides 20011101 |
| Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury. | Peptides 20011101 |
| Chromosomal sublocalization and microsatellite DNA polymorphism of human adrenomedullin gene. | Peptides 20011101 |
| Bioactivity of adrenomedullin and proadrenomedullin N-terminal 20 peptide in man. | Peptides 20011101 |
| Adrenomedullin and related peptides: receptors and accessory proteins. | Peptides 20011101 |
| Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells. | Peptides 20011101 |
| Novel actions of proadrenomedullin N-terminal 20 peptide (PAMP). | Peptides 20011101 |
| Regulation of cardiac adrenomedullin in heart failure. | Peptides 20011101 |
| Effects of adrenomedullin on hypertrophic responses induced by angiotensin II, endothelin-1 and phenylephrine. | Peptides 20011101 |
| Two molecular forms of plasma adrenomedullin during tilt test in healthy subjects. | Peptides 20011101 |
| Adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP) in adrenal chromaffin cells. | Peptides 20011101 |
| Proadrenomedullin N-terminal 20 peptide (PAMP) enhances proliferation of rat zona glomerulosa cells by activating MAPK cascade. | Peptides 20011101 |
| Effects of intracavernous administration of adrenomedullin on erectile function in rats. | Peptides 20011101 |
| Proadrenomedullin-derived peptides as autocrine-paracrine regulators of cell growth. | Histology and histopathology 20011001 |
| [Ameliorative effects of adrenomedullin on rat cardiac sarcoplasmic reticulum injured by isoproterenol]. | Sheng li xue bao : [Acta physiologica Sinica] 20011001 |
| The role of lipopolysaccharide in stimulating adrenomedullin production during polymicrobial sepsis. | Biochimica et biophysica acta 20010928 |
| Adrenomedullin and proadrenomedullin N-terminal 20 peptide induce histamine release from rat peritoneal mast cell. | Regulatory peptides 20010915 |
| Calcitonin gene-related peptide (CGRP), acting via CGRP type 1 receptors, inhibits potassium-stimulated aldosterone secretion and enhances basal catecholamine secretion from rat adrenal gland. | International journal of molecular medicine 20010901 |
| Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat. | Peptides 20010901 |
| AM reverses pressor response to ET-1 independently of NO in rat coronary circulation. | American journal of physiology. Heart and circulatory physiology 20010901 |
| Coordinate regulation of endothelin and adrenomedullin secretion by oxidative stress in endothelial cells. | American journal of physiology. Heart and circulatory physiology 20010901 |
| Expression of the adrenomedullin binding protein, complement factor H, in the pancreas and its physiological impact on insulin secretion. | The Journal of endocrinology 20010901 |
| Effect of neutral endopeptidase inhibition on the actions of adrenomedullin and endothelin-1 in resistance arteries from patients with chronic heart failure. | Hypertension (Dallas, Tex. : 1979) 20010901 |
| Differential adrenomedullin release and endothelin receptor expression in distinct subpopulations of human airway smooth-muscle cells. | American journal of respiratory cell and molecular biology 20010901 |
| Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation. | European journal of obstetrics, gynecology, and reproductive biology 20010801 |
| Comparative analysis of adrenomedullin-like immunoreactivity in the hypothalamus of amphibians. | Microscopy research and technique 20010801 |
| Adrenomedullin is a regulated modulator of neonatal cardiomyocyte hypertrophy in vitro. | Cardiovascular research 20010801 |
| Adrenomedullin (ADM) in the human forearm vascular bed: effect of neutral endopeptidase inhibition and comparison with proadrenomedullin NH2-terminal 20 peptide (PAMP). | British journal of clinical pharmacology 20010801 |
| Effects of adrenomedullin on angiotensin II stimulated atrial natriuretic peptide and arginine vasopressin secretion in healthy humans. | British journal of clinical pharmacology 20010801 |
| CGRP receptors mediating CGRP-, adrenomedullin- and amylin-induced relaxation in porcine coronary arteries. Characterization with 'Compound 1' (WO98/11128), a non-peptide antagonist. | British journal of pharmacology 20010801 |
| Expression of adrenomedullin by human placental cytotrophoblasts and choriocarcinoma JAr cells. | The Journal of clinical endocrinology and metabolism 20010801 |
| Regulation of adrenomedullin secretion in cultured human skin and oral keratinocytes. | The Journal of investigative dermatology 20010801 |
| Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat. | The European journal of neuroscience 20010801 |
| Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells. | Molecular and cellular biochemistry 20010801 |
| Differing thresholds for modulatory effects of adrenomedullin infusion on haemodynamic and hormone responses to angiotensin II and adrenocorticotrophic hormone in healthy volunteers. | Clinical science (London, England : 1979) 20010701 |
| Systemic administration of adrenomedullin(27-52) increases bone volume and strength in male mice. | The Journal of endocrinology 20010701 |
| Autocrine role of adrenomedullin in the human adrenal cortex. | The Journal of endocrinology 20010701 |
| Microsatellite DNA polymorphism of human adrenomedullin gene in normotensive subjects and patients with essential hypertension. | Hypertension (Dallas, Tex. : 1979) 20010701 |
| Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells. | Peptides 20010601 |
| Stimulation of endogenous nitric oxide production is involved in the inhibitory effect of adrenomedullin on aldosterone secretion in the rat. | Peptides 20010601 |
| Effects of TCV-116 on expression of NOS and adrenomedullin in failing heart of Dahl salt-sensitive rats. | Atherosclerosis 20010601 |
| Adrenomedullin inhibits angiotensin II-induced expression of tissue factor and plasminogen activator inhibitor-1 in cultured rat aortic endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20010601 |
| Plasma N-terminal pro-brain natriuretic peptide and adrenomedullin: prognostic utility and prediction of benefit from carvedilol in chronic ischemic left ventricular dysfunction. Australia-New Zealand Heart Failure Group. | Journal of the American College of Cardiology 20010601 |
| Adrenomedullin suppresses fMLP-induced upregulation of CD11b of human neutrophils. | Inflammation 20010601 |
| Adrenomedullin inhibits the pressor effects and decrease in renal blood flow induced by norepinephrine or angiotensin II in anesthetized rats. | Japanese journal of pharmacology 20010601 |
| Glycosylation of human CRLR at Asn123 is required for ligand binding and signaling. | Biochimica et biophysica acta 20010528 |
| Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth. | Oncogene 20010524 |
| Adrenomedullin acts in the rat paraventricular nucleus to decrease blood pressure. | Journal of neuroendocrinology 20010501 |
| Adrenomedullin, a new peptide, in patients with insulinoma. | European journal of endocrinology 20010501 |
| cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels. | Arteriosclerosis, thrombosis, and vascular biology 20010501 |
| Increased endothelin-1 and decreased adrenomedullin gene expression in the stenotic tissue of congenital pelvi-ureteric junction obstruction in children. | BJU international 20010501 |
| Hypotensive and natriuretic actions of adrenomedullin in subjects with chronic renal impairment. | Hypertension (Dallas, Tex. : 1979) 20010501 |
| Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome. | Critical care medicine 20010501 |
| The lungs as an anti-inflammatory organ of the body. | Critical care medicine 20010501 |
| Imbalance between interleukin-6 and adrenomedullin mRNA levels in peripheral blood mononuclear cells of patients with lupus nephritis. | Clinical and experimental immunology 20010501 |
| Plasma adrenomedullin concentrations in patients with adrenal pheochromocytoma. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010501 |
| Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells. | Investigative ophthalmology & visual science 20010401 |
| Endocrine factors related to changes in total peripheral vascular resistance after treatment of thyrotoxic and hypothyroid patients. | European journal of endocrinology 20010401 |
| Roles of protein kinase C and Ca2+-dependent signaling in angiotensin II-induced adrenomedullin production in rat cardiac myocytes. | Journal of hypertension 20010401 |
| Selective inhibition of nicotinic cholinergic receptors by proadrenomedullin N-terminal 12 peptide in bovine adrenal chromaffin cells. | Brain research. Molecular brain research 20010305 |
| Characterization of CGRP(1) receptors in the guinea pig basilar artery. | European journal of pharmacology 20010302 |
| Urinary adrenomedullin is related to ET-1 and salt intake in patients with mild essential hypertension. Salt Sensitivity Group of Italian Society of Hypertension. | American journal of hypertension 20010301 |
| Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade. | Journal of hypertension 20010301 |
| Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries. | American journal of physiology. Heart and circulatory physiology 20010201 |
| Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations. | American journal of respiratory cell and molecular biology 20010201 |
| Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells. | Endocrinology 20010201 |
| Human hepatic stellate cells secrete adrenomedullin: potential autocrine factor in the regulation of cell contractility. | Journal of hepatology 20010201 |
| Adrenomedullin from a pheochromocytoma to the eye: implications of the adrenomedullin research for endocrinology in the 21st century. | The Tohoku journal of experimental medicine 20010201 |
| Regulation of endothelin-1 production in cultured rat vascular smooth muscle cells. | Journal of cardiovascular pharmacology 20010101 |
| Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis. | International review of cytology 20010101 |
| New placental factors: Between implantation and inflammatory reaction. | Early pregnancy (Online) 20010101 |
| Amylin: localization, effects on cerebral arteries and on local cerebral blood flow in the cat. | TheScientificWorldJournal 20010101 |
| Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells. | Journal of neurochemistry 20001101 |
| Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function. | Molecular and cellular endocrinology 20000425 |
| Mammalian calcitonin receptor-like receptor/receptor activity modifying protein complexes define calcitonin gene-related peptide and adrenomedullin receptors in Drosophila Schneider 2 cells. | FEBS letters 20000414 |
| Tissue hypoxygenation activates the adrenomedullin system in vivo. | American journal of physiology. Regulatory, integrative and comparative physiology 20000201 |
| The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor. | Molecular pharmacology 19990601 |
| Regulation of glomerular mesangial cell proliferation in culture by adrenomedullin. | European journal of pharmacology 19990507 |
| Ventricular adrenomedullin levels correlate with the extent of cardiac hypertrophy in rats. | Hypertension (Dallas, Tex. : 1979) 19990501 |
| Effects of centrally of peripherally injected adrenomedullin on reserpine-induced gastric lesions. | European journal of pharmacology 19981030 |
| RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. | Nature 19980528 |
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