200,000+ products from a single source!
sales@angenechem.com
Home > Indoles and Oxindole > 148473-16-9
148473-16-9 | 1H-Indole-2-carboxamide,5-chloro-3-(phenylthio)-
CAS No: 148473-16-9 Catalog No: AG006U6P MDL No:
Product Description
Catalog Number:
AG006U6P
Chemical Name:
1H-Indole-2-carboxamide,5-chloro-3-(phenylthio)-
CAS Number:
148473-16-9
Molecular Formula:
C15H11ClN2OS
Molecular Weight:
302.7786
IUPAC Name:
5-chloro-3-phenylsulfanyl-1H-indole-2-carboxamide
InChI:
InChI=1S/C15H11ClN2OS/c16-9-6-7-12-11(8-9)14(13(18-12)15(17)19)20-10-4-2-1-3-5-10/h1-8,18H,(H2,17,19)
InChI Key:
SEAXPFZOFZLHLQ-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(c1)c(Sc1ccccc1)c([nH]2)C(=O)N
Properties
Complexity:
362
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
302.028g/mol
Formal Charge:
0
Heavy Atom Count:
20
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
302.776g/mol
Monoisotopic Mass:
302.028g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
84.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4
Literature
| Title | Journal |
|---|---|
| Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide. | Journal of medicinal chemistry 20060601 |
| Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives. | Journal of medicinal chemistry 20050113 |
| Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies. | Journal of medicinal chemistry 20030605 |
| 5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase. | Journal of medicinal chemistry 19930430 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.