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146535-06-0

146535-06-0 | 6,7-Dimethoxy-3-(3-thienyl)quinoline

CAS No: 146535-06-0 Catalog No: AG01E26R MDL No:

Product Description

Catalog Number:
AG01E26R
Chemical Name:
6,7-Dimethoxy-3-(3-thienyl)quinoline
CAS Number:
146535-06-0
IUPAC Name:
6,7-dimethoxy-3-thiophen-3-ylquinoline
InChI:
InChI=1S/C15H13NO2S/c1-17-14-6-11-5-12(10-3-4-19-9-10)8-16-13(11)7-15(14)18-2/h3-9H,1-2H3
InChI Key:
KGGRQYJJHXVWSI-UHFFFAOYSA-N

Properties

Complexity:
302  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
271.067g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
271.334g/mol
Monoisotopic Mass:
271.067g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
59.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.4  

Literature

Title Journal
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 1: SAR exploration and effective bioisosteric replacement of a phenyl substituent. Bioorganic & medicinal chemistry letters 20030915
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor. Bioorganic & medicinal chemistry letters 20030915

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