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1463-10-1 | Uridine, 5-methyl-
CAS No: 1463-10-1 Catalog No: AG001DVT MDL No:MFCD00006535
Product Description
Catalog Number:
AG001DVT
Chemical Name:
Uridine, 5-methyl-
CAS Number:
1463-10-1
Molecular Formula:
C10H14N2O6
Molecular Weight:
258.2280
MDL Number:
MFCD00006535
IUPAC Name:
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChI:
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChI Key:
DWRXFEITVBNRMK-JXOAFFINSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cc(C)c(=O)[nH]c1=O
EC Number:
215-973-9
UNII:
ZS1409014A
Properties
Complexity:
409
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
4
Defined Bond Stereocenter Count:
0
Exact Mass:
258.085g/mol
Formal Charge:
0
Heavy Atom Count:
18
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
258.23g/mol
Monoisotopic Mass:
258.085g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
119A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.6
Literature
| Title | Journal |
|---|---|
| Photochemical control of RNA structure by disrupting π-stacking. | Journal of the American Chemical Society 20120801 |
| Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. | RNA (New York, N.Y.) 20120301 |
| Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix. | Bioorganic & medicinal chemistry letters 20120301 |
| Improved synthesis of 2'-deoxyadenosine and 5-methyluridine by Escherichia coli using an auto-induction system. | World journal of microbiology & biotechnology 20120201 |
| Defining a process operating window for the synthesis of 5-methyluridine by transglycosylation of guanosine and thymine. | Journal of biotechnology 20110110 |
| The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. | PloS one 20110101 |
| A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation. | Silence 20110101 |
| Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro. | RNA (New York, N.Y.) 20100601 |
| Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100501 |
| Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA. | Biochemical and biophysical research communications 20100205 |
| A study on the interaction between 5-Methyluridine and human serum albumin using fluorescence quenching method and molecular modeling. | Journal of molecular modeling 20100201 |
| Stereochemical mechanisms of tRNA methyltransferases. | FEBS letters 20100121 |
| [Determination of protein in biological samples by synchronous fluorescence]. | Guang pu xue yu guang pu fen xi = Guang pu 20090901 |
| Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine. | Bioorganic & medicinal chemistry 20081001 |
| Crystallization and preliminary X-ray crystallographic characterization of TrmFO, a folate-dependent tRNA methyltransferase from Thermotoga maritima. | Acta crystallographica. Section F, Structural biology and crystallization communications 20080301 |
| Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography. | International journal of molecular sciences 20080301 |
| Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. | BMC biochemistry 20070101 |
| A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs. | Journal of molecular biology 20060929 |
| 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods. | Bioorganic & medicinal chemistry letters 20060215 |
| Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA. | The Journal of biological chemistry 20060127 |
| Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system. | Bioorganic & medicinal chemistry 20050301 |
| Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives. | Nucleosides, nucleotides & nucleic acids 20050101 |
| Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. | Bioorganic & medicinal chemistry letters 20030915 |
| Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli. | The Journal of biological chemistry 20020315 |
| Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. | RNA (New York, N.Y.) 20020301 |
| Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides. | The Journal of organic chemistry 20010420 |
| Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine. | Journal of immunology (Baltimore, Md. : 1950) 19840601 |
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