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145514-00-7 | 1,3-Dioxolane-2-methanol, 4-(2-amino-6-chloro-9H-purin-9-yl)-, (2R,4S)-
CAS No: 145514-00-7 Catalog No: AG001D4Q MDL No:
Product Description
Catalog Number:
AG001D4Q
Chemical Name:
1,3-Dioxolane-2-methanol, 4-(2-amino-6-chloro-9H-purin-9-yl)-, (2R,4S)-
CAS Number:
145514-00-7
Molecular Formula:
C9H10ClN5O3
Molecular Weight:
271.6604
IUPAC Name:
[4-(2-amino-6-chloropurin-9-yl)-1,3-dioxolan-2-yl]methanol
InChI:
InChI=1S/C9H10ClN5O3/c10-7-6-8(14-9(11)13-7)15(3-12-6)4-2-17-5(1-16)18-4/h3-5,16H,1-2H2,(H2,11,13,14)
InChI Key:
AHZYYPABMTXZCC-UHFFFAOYSA-N
SMILES:
OC[C@@H]1OC[C@H](O1)n1cnc2c1nc(N)nc2Cl
Properties
Complexity:
312
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
271.047g/mol
Formal Charge:
0
Heavy Atom Count:
18
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
271.661g/mol
Monoisotopic Mass:
271.047g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
108A^2
Undefined Atom Stereocenter Count:
2
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6
Literature
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| Activation of metabotropic glutamate receptors induces propagating network oscillations in the intact cerebral cortex of the newborn mouse. | Neuropharmacology 20060901 |
| Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine. | Psychopharmacology 20050401 |
| A chemical LTP induced by co-activation of metabotropic and N-methyl-D-aspartate glutamate receptors in hippocampal CA1 neurons. | Brain research 20040227 |
| Influence of membrane properties on spike synchronization in neurons: theory and experiments. | Network (Bristol, England) 20031101 |
| Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound. | Brain research 20030919 |
| Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity? | Neuropharmacology 20030501 |
| Interactions between adenosine and metabotropic glutamate receptors in the rat hippocampal slice. | British journal of pharmacology 20030301 |
| The role of Ca2+ in the generation of spontaneous astrocytic Ca2+ oscillations. | Neuroscience 20030101 |
| Glutamate receptors communicate with Na+/K+-ATPase in rat cerebellum granule cells: demonstration of differences in the action of several metabotropic and ionotropic glutamate agonists on intracellular reactive oxygen species and the sodium pump. | Journal of molecular neuroscience : MN 20030101 |
| Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses. | Molecular and cellular neurosciences 20020501 |
| Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus. | Neuropharmacology 20020301 |
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