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145307-34-2 | 1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
CAS No: 145307-34-2 Catalog No: AG001KS5 MDL No:
Product Description
Catalog Number:
AG001KS5
Chemical Name:
1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), (1R,3S)-
CAS Number:
145307-34-2
Molecular Formula:
C20H28ClNO3
Molecular Weight:
365.8942
IUPAC Name:
(1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol;hydrochloride
InChI:
InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1
InChI Key:
BWHPNJVKFAPVOG-QYFJGNGUSA-N
SMILES:
NCC1OC(Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3.Cl
UNII:
WA6RGP1J4W
Properties
Complexity:
454
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
2
Defined Bond Stereocenter Count:
0
Exact Mass:
365.176g/mol
Formal Charge:
0
Heavy Atom Count:
25
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
365.898g/mol
Monoisotopic Mass:
365.176g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
75.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats. | The international journal of neuropsychopharmacology 20090801 |
| Neonatal tactile stimulation enhances spatial working memory, prefrontal long-term potentiation, and D1 receptor activation in adult rats. | Neurobiology of learning and memory 20080501 |
| Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors. | Neuropharmacology 20070201 |
| Effect of dopamine D1 receptor antagonist SCH23390 and D1 agonist A77636 on active allothetic place avoidance, a spatial cognition task. | Behavioural brain research 20060925 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats. | European journal of pharmacology 20060227 |
| Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists. | Molecular pharmacology 20051001 |
| Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. | Biological psychiatry 20050601 |
| Negative feedback regulation of nigrostriatal dopamine release: mediation by striatal D1 receptors. | The Journal of pharmacology and experimental therapeutics 20041001 |
| The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration. | Journal of neural transmission (Vienna, Austria : 1996) 20020201 |
| Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents. | Psychopharmacology 20020101 |
| Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats. | Psychopharmacology 20010401 |
| Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat. | Brain research 20010302 |
| Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys. | Neurology 19970801 |
| Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. | Journal of medicinal chemistry 19970523 |
| Chronic L-DOPA administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (Callithrix Jacchus). | Movement disorders : official journal of the Movement Disorder Society 19951101 |
| Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys. | The Journal of pharmacology and experimental therapeutics 19931001 |
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