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145-63-1

145-63-1 | 1,3,5-Naphthalenetrisulfonic acid, 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-

CAS No: 145-63-1 Catalog No: AG001KFK MDL No:

Product Description

Catalog Number:
AG001KFK
Chemical Name:
1,3,5-Naphthalenetrisulfonic acid, 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-
CAS Number:
145-63-1
Molecular Formula:
C51H40N6O23S6
Molecular Weight:
1297.2797
IUPAC Name:
8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid
InChI:
InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)
InChI Key:
FIAFUQMPZJWCLV-UHFFFAOYSA-N
SMILES:
O=C(Nc1cccc(c1)C(=O)Nc1cc(ccc1C)C(=O)Nc1ccc(c2c1c(cc(c2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)Nc1cccc(c1)C(=O)Nc1cc(ccc1C)C(=O)Nc1ccc(c2c1c(cc(c2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O
EC Number:
205-658-4
UNII:
6032D45BEM
NSC Number:
34936

Properties

Complexity:
3020  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
1296.047g/mol
Formal Charge:
0
Heavy Atom Count:
86  
Hydrogen Bond Acceptor Count:
23  
Hydrogen Bond Donor Count:
12  
Isotope Atom Count:
0
Molecular Weight:
1297.26g/mol
Monoisotopic Mass:
1296.047g/mol
Rotatable Bond Count:
16  
Topological Polar Surface Area:
534A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.5  

Literature

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A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS. Annals of hematology 20110601
Purification and concentration of non-infectious West Nile virus-like particles and infectious virions using a pseudo-affinity Cellufine Sulfate column. Journal of virological methods 20110601
Coupled ATP and potassium efflux from intercalated cells. American journal of physiology. Renal physiology 20110601
Distraction osteogenesis-induced muscle fibrosis may not be associated with TGF-β1. Journal of pediatric orthopedics 20110601
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Suramin inhibits renal fibrosis in chronic kidney disease. Journal of the American Society of Nephrology : JASN 20110601
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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS neglected tropical diseases 20110601
P2Y2 receptor-mediated modulation of estrogen-induced proliferation of breast cancer cells. Molecular and cellular endocrinology 20110516
Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress. Biochemical pharmacology 20110515
Generation of anti-trypanosomal agents through concise synthesis and structural diversification of sesquiterpene analogues. Journal of the American Chemical Society 20110511
A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling. British journal of cancer 20110510
Nerve-evoked constriction of rat tail veins is potentiated and venous diameter is reduced after chronic spinal cord transection. Journal of neurotrauma 20110501
Ethnogeographical structure of hepatitis B virus genotype distribution in Indonesia and discovery of a new subgenotype, B9. Archives of virology 20110501
ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock. Experimental dermatology 20110501
P2X(7) receptor antagonists display agonist-like effects on cell signaling proteins. Biochimica et biophysica acta 20110501
Identification of P2X₃ and P2X₇ purinergic receptors activated by ATP in rat lacrimal gland. Investigative ophthalmology & visual science 20110501
Tissue protective and anti-fibrotic actions of suramin: new uses of an old drug. Current clinical pharmacology 20110501
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. Bioorganic & medicinal chemistry letters 20110501
ATP induces contraction mediated by the P2Y(2) receptor in rat intestinal subepithelial myofibroblasts. European journal of pharmacology 20110425
Pomolic acid of Licania pittieri elicits endothelium-dependent relaxation in rat aortic rings. Phytomedicine : international journal of phytotherapy and phytopharmacology 20110415
High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay. Protein expression and purification 20110401
Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking. Molecular pharmacology 20110401
The penultimate arginine of the carboxyl terminus determines slow desensitization in a P2X receptor from the cattle tick Boophilus microplus. Molecular pharmacology 20110401
Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. PLoS neglected tropical diseases 20110401
P2Y purinergic regulation of the glycine neurotransmitter transporters. The Journal of biological chemistry 20110325
Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. Journal of ethnopharmacology 20110324
CDP-choline-induced contractions in the mouse gastric fundus through purinoceptors and Rho/Rho-kinase signalling. Life sciences 20110314
Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents. Journal of medicinal chemistry 20110310
Acetylene compound isolated from Atractylodes japonica stimulates the contractility of rat distal colon via inhibiting the nitrergic-purinergic relaxation. Journal of ethnopharmacology 20110308
Suramab, a novel antiangiogenic agent, reduces tumor growth and corneal neovascularization. Cancer chemotherapy and pharmacology 20110301
Activation of P2X receptors induces apoptosis in human retinal pigment epithelium. Investigative ophthalmology & visual science 20110301
Modulation by endogenously released ATP and opioids of chromaffin cell calcium channels in mouse adrenal slices. American journal of physiology. Cell physiology 20110301
Formation of cysts by principal-like MDCK cells depends on the synergy of cAMP- and ATP-mediated fluid secretion. Journal of molecular medicine (Berlin, Germany) 20110301
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. Bioorganic & medicinal chemistry 20110301
Clinical presentation of T.b. rhodesiense sleeping sickness in second stage patients from Tanzania and Uganda. PLoS neglected tropical diseases 20110301
Postnatal development of excitatory innervations in longitudinal smooth muscle of the chicken anterior mesenteric artery. Life sciences 20110227
Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin. International journal of cardiology 20110217
Purinergic P2X7 receptor regulates lung surfactant secretion in a paracrine manner. Journal of cell science 20110215
PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models. British journal of cancer 20110215
Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. Journal of medicinal chemistry 20110210
Ivermectin, 'wonder drug' from Japan: the human use perspective. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110210
Development of polymer-membrane based electrodes for suramin. Analytica chimica acta 20110207
Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells. The Journal of biological chemistry 20110204
Purinergic mechanisms of lateral parabrachial nucleus facilitate sodium depletion-induced NaCl intake. Brain research 20110204
β-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons. Gastroenterology 20110201
In airways ATP refills sarcoplasmic reticulum via P2X smooth muscle receptors and induces contraction through P2Y epithelial receptors. Pflugers Archiv : European journal of physiology 20110201
The distribution of nifurtimox across the healthy and trypanosome-infected murine blood-brain and blood-cerebrospinal fluid barriers. The Journal of pharmacology and experimental therapeutics 20110201
Time course of skeletal muscle regeneration after severe trauma. Acta orthopaedica 20110201
Maintained tubuloglomerular feedback responses during acute inhibition of P2 purinergic receptors in mice. American journal of physiology. Renal physiology 20110201
Present state and future perspectives of using pluripotent stem cells in toxicology research. Archives of toxicology 20110201
Application of isothermal titration calorimetry and column chromatography for identification of biomolecular targets. Nature protocols 20110201
Population vulnerability and disability in Kenya's tsetse fly habitats. PLoS neglected tropical diseases 20110201
2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approach. PLoS neglected tropical diseases 20110201
Extracellular Nucleotides Can Induce Chemokine (C-C motif) Ligand 2 Expression in Human Vascular Smooth Muscle Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20110201
Purinergic modulation of glucose uptake into cultured rat podocytes: effect of diabetic milieu. Biochemical and biophysical research communications 20110114
Can guanine-based purines be considered modulators of intestinal motility in rodents? European journal of pharmacology 20110110
Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110105
Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages. Immunobiology 20110101
G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling. Cardiovascular research 20110101
The stress signal extracellular ATP modulates antiflagellin immune responses in intestinal epithelial cells. Inflammatory bowel diseases 20110101
Propionate-induced epithelial K(+) and Cl(-)/HCO3(-) secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon. Pflugers Archiv : European journal of physiology 20110101
Identification of clinically used drugs that activate pregnane X receptors. Drug metabolism and disposition: the biological fate of chemicals 20110101
Expression of acid-sensing ion channels in intestinal epithelial cells and their role in the regulation of duodenal mucosal bicarbonate secretion. Acta physiologica (Oxford, England) 20110101
Ventilatory and carotid body chemoreceptor responses to purinergic P2X receptor antagonists in newborn rats. Journal of applied physiology (Bethesda, Md. : 1985) 20110101
Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-β1 blocker. Muscle & nerve 20110101
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorganic & medicinal chemistry 20110101
A nicardipine-sensitive Ca2+ entry contributes to the hypotonicity-induced increase in [Ca2+]i of principal cells in rat cortical collecting duct. Cell calcium 20110101
Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission. PloS one 20110101
Effects of polymorphisms in ovine and caprine prion protein alleles on cell-free conversion. Veterinary research 20110101
Complementary effects of extracellular nucleotides and platelet-derived extracts on angiogenesis of vasa vasorum endothelial cells in vitro and subcutaneous Matrigel plugs in vivo. Vascular cell 20110101
Mometasone and desloratadine additive effect on eosinophil survival and cytokine secretion from epithelial cells. Respiratory research 20110101
Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. PloS one 20110101
Modulation of acetylation: creating a pro-survival and anti-inflammatory phenotype in lethal hemorrhagic and septic shock. Journal of biomedicine & biotechnology 20110101
Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes. PloS one 20110101
Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe Merr. Cancer cell international 20110101
Suramin inhibits the early effects of PLA(2) neurotoxins at mouse neuromuscular junctions: A twitch tension study. Journal of venom research 20110101
Advances in molecular characterization and targeted therapy in dermatofibrosarcoma protuberans. Sarcoma 20110101
Pharmacological evaluation of rat dorsal root ganglion neurons as an in vitro model for diabetic neuropathy. Journal of pain research 20110101
The structural features of Trask that mediate its anti-adhesive functions. PloS one 20110101
The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo. PloS one 20110101
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Frontiers in pharmacology 20110101
4th Edition of the International Autologous and Allogeneic Cell Therapy for Solid Tumors (ATST) Meeting. Journal of Cancer 20110101
Trypanosome prereplication machinery: a potential new target for an old problem. Enzyme research 20110101
Very-low-density lipoprotein: complex particles in cardiac energy metabolism. Journal of lipids 20110101
Role of TGF-β signaling in inherited and acquired myopathies. Skeletal muscle 20110101
Aberrant repair and fibrosis development in skeletal muscle. Skeletal muscle 20110101
Interferon impedes an early step of hepatitis delta virus infection. PloS one 20110101
Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children. Malaria journal 20110101
Diacylglycerol signaling underlies astrocytic ATP release. Neural plasticity 20110101
Purinergic activation of Ca2+-permeable TRPV4 channels is essential for mechano-sensitivity in the aldosterone-sensitive distal nephron. PloS one 20110101
In Mycoplasma hominis the OppA-mediated cytoadhesion depends on its ATPase activity. BMC microbiology 20110101
Purinergic receptor antagonists inhibit odorant-mediated CREB phosphorylation in sustentacular cells of mouse olfactory epithelium. BMC neuroscience 20110101
Neglected disease - african sleeping sickness: recent synthetic and modeling advances. Scientia pharmaceutica 20110101
Prevalence and types of coinfections in sleeping sickness patients in kenya (2000/2009). Journal of tropical medicine 20110101
Transient inactivation of the medial prefrontal cortex affects both anxiety and decision-making in male wistar rats. Frontiers in neuroscience 20110101
Structure and behavior of human α-thrombin upon ligand recognition: thermodynamic and molecular dynamics studies. PloS one 20110101
Targeting HDACs: a promising therapy for Alzheimer's disease. Oxidative medicine and cellular longevity 20110101
The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse. PloS one 20110101
Targets in epigenetics: inhibiting the methyl writers of the histone code. Current chemical genomics 20110101
Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinate. BMC neuroscience 20110101
Some aspects of purinergic signaling in the ventricular system of porcine brain. Acta veterinaria Scandinavica 20110101
Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites. PloS one 20110101
Onchocerciasis in the Americas: from arrival to (near) elimination. Parasites & vectors 20110101
Ocular onchocerciasis: current management and future prospects. Clinical ophthalmology (Auckland, N.Z.) 20110101
The repetitive cytoskeletal protein H49 of Trypanosoma cruzi is a calpain-like protein located at the flagellum attachment zone. PloS one 20110101
The role of uridine adenosine tetraphosphate in the vascular system. Advances in pharmacological sciences 20110101
Modulation of phosphofructokinase (PFK) from Setaria cervi, a bovine filarial parasite, by different effectors and its interaction with some antifilarials. Parasites & vectors 20110101
Membrane-lipid therapy in operation: the HSP co-inducer BGP-15 activates stress signal transduction pathways by remodeling plasma membrane rafts. PloS one 20110101
Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells. Nutrition & metabolism 20110101
Characterisation of P2X receptors expressed in rat pulmonary arteries. European journal of pharmacology 20101215
Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. The Journal of biological chemistry 20101210
Bladder tissue pharmacokinetics of intravesical mitomycin C and suramin in dogs. The AAPS journal 20101201
Core/shell microspheres via coaxial electrohydrodynamic atomization for sequential and parallel release of drugs. Journal of biomedical materials research. Part A 20101201
Dexamethasone enhances ATP-induced inflammatory responses in endothelial cells. The Journal of pharmacology and experimental therapeutics 20101201
Astrocytes in the retrotrapezoid nucleus sense H+ by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism. Journal of neurophysiology 20101201
Identification of specific inhibitors for a trypanosomatid RNA editing reaction. RNA (New York, N.Y.) 20101201
Chemotherapy against human African trypanosomiasis: is there a road to success? Parasitology 20101201
Dyes, trypanosomiasis and DNA: a historical and critical review. Biotechnic & histochemistry : official publication of the Biological Stain Commission 20101201
Focus-specific clinical profiles in human African Trypanosomiasis caused by Trypanosoma brucei rhodesiense. PLoS neglected tropical diseases 20101201
Pitfalls in the diagnosis of trypanosomiasis in low endemic countries: a case report. PLoS neglected tropical diseases 20101201
Purinergic receptor-mediated Ca signaling in the olfactory bulb and the neurogenic area of the lateral ventricles. Purinergic signalling 20101201
Spider-venom peptides as therapeutics. Toxins 20101201
The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin. Biochemical and biophysical research communications 20101126
Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis. Biochemical pharmacology 20101115
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. Bioorganic & medicinal chemistry 20101115
Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer. Cancer chemotherapy and pharmacology 20101101
The heat-pipe resembling action of boiling bubbles in endovenous laser ablation. Lasers in medical science 20101101
Adrenergic receptor activation involves ATP release and feedback through purinergic receptors. American journal of physiology. Cell physiology 20101101
Purine receptors modulate chondrocyte extracellular inorganic pyrophosphate production. Osteoarthritis and cartilage 20101101
Paclitaxel and suramin-loaded core/shell microspheres in the treatment of brain tumors. Biomaterials 20101101
Direct demonstration of tubular fluid flow sensing by macula densa cells. American journal of physiology. Renal physiology 20101101
The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens. The Journal of pharmacology and experimental therapeutics 20101101
Sympathetic vasoconstriction is potentiated in arteries caudal but not rostral to a spinal cord transection in rats. Journal of neurotrauma 20101101
Central nervous system (CNS) delivery of glucocorticoids is fine-tuned by saturable transporters at the blood-CNS barriers and nonbarrier regions. Endocrinology 20101101
Structural interpretation of P2X receptor mutagenesis studies on drug action. British journal of pharmacology 20101101
Quantifying the burden of rhodesiense sleeping sickness in Urambo District, Tanzania. PLoS neglected tropical diseases 20101101
Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors. Oncotarget 20101101
Ribosome-inactivating proteins: from plant defense to tumor attack. Toxins 20101101
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury. Neuroscience 20101027
Extracellular nucleotides elicit cytosolic free calcium oscillations in Arabidopsis. Plant physiology 20101001
Regulated maturation of malaria merozoite surface protein-1 is essential for parasite growth. Molecular microbiology 20101001
Differential effects of uridine adenosine tetraphosphate on purinoceptors in the rat isolated perfused kidney. British journal of pharmacology 20101001
Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival. PLoS pathogens 20101001
Pharmacological properties and physiological function of a P2X-like current in single proximal tubule cells isolated from frog kidney. The Journal of membrane biology 20101001
P2X and P2Y Receptors Mediate Contraction Induced by Electrical Field Stimulation in Feline Esophageal Smooth Muscle. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20101001
p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. The Journal of biological chemistry 20100910
New discoveries in the transmission biology of sleeping sickness parasites: applying the basics. Journal of molecular medicine (Berlin, Germany) 20100901
Biochemical characterization of an ecto-ATP diphosphohydrolase activity in Candida parapsilosis and its possible role in adenosine acquisition and pathogenesis. FEMS yeast research 20100901
Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors. Purinergic signalling 20100901
Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds. Journal of medicinal chemistry 20100826
Discovery and mechanistic study of a class of protein arginine methylation inhibitors. Journal of medicinal chemistry 20100826
Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia. Biochimica et biophysica acta 20100801
Functional ligand-gated purinergic receptors (P2X) in rat vestibular ganglion neurons. Hearing research 20100801
Ca(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells. British journal of pharmacology 20100801
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1. PLoS neglected tropical diseases 20100801
Responses induced by acetylcholine and ATP in the rabbit petrosal ganglion. Respiratory physiology & neurobiology 20100731
Characterisation of the heterotrimeric presynaptic phospholipase A(2) neurotoxin complex from the venom of the common death adder (Acanthophis antarcticus). Biochemical pharmacology 20100715
Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness. Journal of medicinal chemistry 20100708
Arsenic inhibits myogenic differentiation and muscle regeneration. Environmental health perspectives 20100701
Blocking P2X receptors can inhibit the injury-induced proliferation of olfactory epithelium progenitor cells in adult mouse. International journal of pediatric otorhinolaryngology 20100701
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder. Basic & clinical pharmacology & toxicology 20100701
Visualization of Ins(1,4,5)P3 dynamics in living cells: two distinct pathways for Ins(1,4,5)P3 generation following mechanical stimulation of HSY-EA1 cells. Journal of cell science 20100701
Nickel sulfate induces location-dependent atrophy of mouse olfactory epithelium: protective and proliferative role of purinergic receptor activation. Toxicological sciences : an official journal of the Society of Toxicology 20100601
P2Y2 receptors mediate ATP-induced resensitization of TRPV1 expressed by kidney projecting sensory neurons. American journal of physiology. Regulatory, integrative and comparative physiology 20100601
Identification of stage biomarkers for human African trypanosomiasis. The American journal of tropical medicine and hygiene 20100601
Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90. PLoS neglected tropical diseases 20100601
Intracellular Ca2+ responses and cell volume regulation upon cholinergic and purinergic stimulation in an immortalized salivary cell line. European journal of oral sciences 20100601
Purinoreceptor-mediated current in myocytes from renal resistance arteries. British journal of pharmacology 20100601
Activation of the MAPKs ERK1/2 by cell swelling in turbot hepatocytes. Biology of the cell 20100519
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. Veterinary parasitology 20100511
Butyl benzyl phthalate suppresses the ATP-induced cell proliferation in human osteosarcoma HOS cells. Toxicology and applied pharmacology 20100501
Carbonized blood deposited on fibres during 810, 940 and 1,470 nm endovenous laser ablation: thickness and absorption by optical coherence tomography. Lasers in medical science 20100501
Presynaptic inhibition of neural vasodilator pathways to submucosal arterioles by release of purines from sympathetic nerves. American journal of physiology. Gastrointestinal and liver physiology 20100501
New structure enlivens interest in P2X receptors. Trends in pharmacological sciences 20100501
Chemerin, a novel adipokine in the regulation of angiogenesis. The Journal of clinical endocrinology and metabolism 20100501
Controlling sleeping sickness--'when will they ever learn?'. PLoS neglected tropical diseases 20100501
Involvement of peripheral adenosine 5'-triphosphate and P2X purinoceptor in pain-related behavior produced by orthotopic melanoma inoculation in mice. The European journal of neuroscience 20100501
Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. Journal of medicinal chemistry 20100422
Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100401
Cyclic loading opens hemichannels to release ATP as part of a chondrocyte mechanotransduction pathway. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20100401
Differential effect of L-cysteine in isolated whole-bladder preparations from neonatal and adult rats. The Journal of pharmacology and experimental therapeutics 20100401
Immunohistological studies on neoplasms of female and male Onchocerca volvulus: filarial origin and absence of Wolbachia from tumor cells. Parasitology 20100401
Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9. Glycoconjugate journal 20100401
A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity. PLoS neglected tropical diseases 20100401
Evaluation of anti-allergic activity of gossypin and suramin in mast cell-mediated allergy model. Indian journal of biochemistry & biophysics 20100401
Modulation of cell surface architecture in gastrulating chick embryo in response to altered fibroblast growth factor (FGF) signaling. Indian journal of experimental biology 20100401
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids. Journal of medicinal chemistry 20100311
P2Y4-mediated regulation of Na+ absorption in the Reissner's membrane of the cochlea. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100310
Shockwaves increase T-cell proliferation and IL-2 expression through ATP release, P2X7 receptors, and FAK activation. American journal of physiology. Cell physiology 20100301
NTPDase family in zebrafish: Nucleotide hydrolysis, molecular identification and gene expression profiles in brain, liver and heart. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100301
Modulation of epithelial sodium channel activity by lipopolysaccharide in alveolar type II cells: involvement of purinergic signaling. American journal of physiology. Lung cellular and molecular physiology 20100301
Involvement of purinergic signaling in cellular response to gamma radiation. Radiation research 20100301
The P2Y2 receptor sensitizes mouse bladder sensory neurons and facilitates purinergic currents. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100210
Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia. Neuron glia biology 20100201
Platelets in defense against bacterial pathogens. Cellular and molecular life sciences : CMLS 20100201
Novel excitatory effects of adenosine triphosphate on contractile and pacemaker activity in rabbit urethral smooth muscle. The Journal of urology 20100201
Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro. Molecular immunology 20100201
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS pathogens 20100201
Angiogenesis: Future of pharmacological modulation. Indian journal of pharmacology 20100201
Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells. Respiratory physiology & neurobiology 20100131
Two suramin binding sites are present in guinea pig but only one in murine native P2X myenteric receptors. European journal of pharmacology 20100125
Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase. Analytical biochemistry 20100115
Human African trypanosomiasis. Lancet (London, England) 20100109
Killer coma: the evolving story of sleeping sickness treatment. Lancet (London, England) 20100109
Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia. Blood 20100107
Organic dyes as small molecule protein-protein interaction inhibitors for the CD40-CD154 costimulatory interaction. Journal of molecular recognition : JMR 20100101
Recent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation. Recent patents on CNS drug discovery 20100101
The P2 receptor antagonist PPADS abrogates LPS-induced neutrophil migration in the murine air pouch via inhibition of MIP-2 and KC production. Molecular immunology 20100101
The effect of subconjunctival suramin on corneal neovascularization in rabbits. Cornea 20100101
Extracellular ATP and P2Y2 receptors mediate intercellular Ca(2+) waves induced by mechanical stimulation in submandibular gland cells: Role of mitochondrial regulation of store operated Ca(2+) entry. Cell calcium 20100101
Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges. Journal of oncology 20100101
Phosphatase inhibitors with anti-angiogenic effect in vitro. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20100101
P2Y receptors and atherosclerosis in apolipoprotein E-deficient mice. British journal of pharmacology 20100101
Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells. BMC cancer 20100101
Trypanosomatid parasites causing neglected diseases. Current medicinal chemistry 20100101
Cerebral and peripheral changes occurring in nitric oxide (NO) synthesis in a rat model of sleeping sickness: identification of brain iNOS expressing cells. PloS one 20100101
Immunobiology of African trypanosomes: need of alternative interventions. Journal of biomedicine & biotechnology 20100101
Antimicrobial resistance, class 1 integrons, and genomic island 1 in Salmonella isolates from Vietnam. PloS one 20100101
Evidence that low endocytic activity is not directly responsible for human serum resistance in the insect form of African trypanosomes. BMC research notes 20100101
The development of drugs for treatment of sleeping sickness: a historical review. Parasites & vectors 20100101
Proteomics of Trypanosoma evansi infection in rodents. PloS one 20100101
Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs. PloS one 20100101
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[Regulation by cyclic adenosine monophosphate of functional activity of the adenylyl cyclase system of the infusorian Dileptus anser]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20100101
Pharmacokinetics of Linezolid and Ertapenem in experimental parapneumonic pleural effusion. Journal of inflammation (London, England) 20100101
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Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities. PloS one 20100101
Cross-sectional study of availability and pharmaceutical quality of antibiotics requested with or without prescription (Over The Counter) in Surabaya, Indonesia. BMC infectious diseases 20100101
Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells. Reproductive biology and endocrinology : RB&E 20100101
UV-B induced transcript accumulation of DAHP synthase in suspension-cultured Catharanthus roseus cells. Journal of molecular signaling 20100101
Higher concentrations of extracellular ATP suppress proliferation of Caco-2 human colonic cancer cells via an unknown receptor involving PKC inhibition. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virology journal 20100101
Radio Frequency Ablation in Drug Resistant Chemotherapy-induced Peripheral Neuropathy: A Case Report and Review of Literature. Indian journal of palliative care 20100101
Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi. BMC complementary and alternative medicine 20100101
Novel method of monitoring trace cytokines and activated STAT molecules in the paws of arthritic mice using multiplex bead technology. BMC immunology 20100101
Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. PloS one 20100101
Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus. PloS one 20100101
Optimal management of cancer anorexia-cachexia syndrome. Cancer management and research 20100101
Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells. The open microbiology journal 20100101
A comparative analysis of the Libyan national essential medicines list and the WHO model list of essential medicines. The Libyan journal of medicine 20100101
[The sleeping disease drug Germanine as an instrument for propaganda: reception in literature and film during National Socialism]. Wurzburger medizinhistorische Mitteilungen 20100101
Intra-Laboratory Pre-Validation of a Human Cell Based in vitro Angiogenesis Assay for Testing Angiogenesis Modulators. Frontiers in pharmacology 20100101
Use of sulodexide in patients with peripheral vascular disease. Journal of blood medicine 20100101
ATP released by electrical stimuli elicits calcium transients and gene expression in skeletal muscle. The Journal of biological chemistry 20091211
Functional characterization of intracellular Dictyostelium discoideum P2X receptors. The Journal of biological chemistry 20091211
Spontaneous calcium transients in cultured cortical networks during development. IEEE transactions on bio-medical engineering 20091201
Melanin-concentrating hormone reduces somatolactin release from cultured goldfish pituitary cells. The Journal of endocrinology 20091201
Nicotinic acetylcholine receptors do not mediate excitatory transmission in young rat carotid body. Journal of applied physiology (Bethesda, Md. : 1985) 20091201
Spontaneous oscillations in intracellular Ca(2+) concentration via purinergic receptors elicit transient cell swelling in rat parotid ducts. American journal of physiology. Gastrointestinal and liver physiology 20091201
Inhibition of cholesterol recycling impairs cellular PrP(Sc) propagation. Cellular and molecular life sciences : CMLS 20091201
Adenosine 5'-triphosphate stimulates the increase of TGF-beta1 in rat mesangial cells under high-glucose conditions via reactive oxygen species and ERK1/2. Acta pharmacologica Sinica 20091201
P2X2, P2X4 and P2Y1 receptors elevate intracellular Ca2+ in mouse embryonic stem cell-derived GABAergic neurons. British journal of pharmacology 20091201
Modulation of the activity of two pacemakers by transmural nerve stimulation in circular smooth muscle preparations isolated from the rat proximal colon. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20091201
Blockade of P2X receptor prevents astroglial death in the dentate gyrus following pilocarpine-induced status epilepticus. Neurological research 20091101
Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells. Acta physiologica (Oxford, England) 20091101
Changes in adenosine triphosphate-stimulated ATP release suggest association between cytokine and purinergic signaling in bladder urothelial cells. Urology 20091101
Activation of purinergic receptors by ATP induces ventricular tachycardia by membrane depolarization and modifications of Ca2+ homeostasis. Journal of molecular and cellular cardiology 20091101
Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor. The Journal of pharmacology and experimental therapeutics 20091101
The outcome of the axillofemoral bypass: a retrospective analysis of 45 patients. World journal of surgery 20091101
Extracellular ATP inhibits transport in medullary thick ascending limbs: role of P2X receptors. American journal of physiology. Renal physiology 20091101
The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers. Hepatology (Baltimore, Md.) 20091101
East African trypanosomiasis in a pregnant traveler. Emerging infectious diseases 20091101
Immunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposure. PLoS neglected tropical diseases 20091101
Heparin and suramin alter plitidepsin uptake via inhibition of GPCR coupled signaling. Journal of chemotherapy (Florence, Italy) 20091101
Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS pathogens 20091101
Identification and functional characterization of the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) in biliary epithelium. American journal of physiology. Gastrointestinal and liver physiology 20091101
Increase of intracellular Ca2+ by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat. The Journal of comparative neurology 20091010
Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor. European journal of immunology 20091001
Mechanism involved in phagocytosis and killing of Listeria monocytogenes by Acanthamoeba polyphaga. Parasitology research 20091001
ATP in the pathogenesis of lung emphysema. European journal of pharmacology 20091001
TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Archiv : European journal of physiology 20091001
P2X purinoceptors mediate an endothelium-dependent hyperpolarization in longitudinal smooth muscle of anterior mesenteric artery in young chickens. British journal of pharmacology 20091001
Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. The American journal of pathology 20091001
Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & medicinal chemistry 20091001
Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion. European journal of immunology 20091001
Activation of purinergic receptors induces proliferation and neuronal differentiation in Swiss Webster mouse olfactory epithelium. Neuroscience 20090929
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences. Journal of medicinal chemistry 20090924
Spontaneous glial calcium waves in the retina develop over early adulthood. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909
In vitro interaction between suramin and fluvastatin against clinically important Zygomycetes. Mycoses 20090901
Neurokinin 1 receptor activates transient receptor potential-like currents in noradrenergic A7 neurons in rats. Molecular and cellular neurosciences 20090901
Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs. American journal of physiology. Renal physiology 20090901
Pharmacological properties of ATP-sensitive purinergic receptors expressed in human G292 osteoblastic cells. European journal of pharmacology 20090901
Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism. PLoS neglected tropical diseases 20090901
Release of adenosine and ATP during ischemia and epilepsy. Current neuropharmacology 20090901
Allosteric interaction of the anticholinergic drug [N-(4-phenyl)-phenacyl-l-hyoscyamine] (Phenthonium) with nicotinic receptors of post-ganglionic sympathetic neurons of the rat vas deferens. European journal of pharmacology 20090815
ATP-dependent paracrine communication between enteric neurons and glia in a primary cell culture derived from embryonic mice. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090801
Clodronate-induced cell apoptosis in human thyroid carcinoma is mediated via the P2 receptor signaling pathway. The Journal of pharmacology and experimental therapeutics 20090801
Role of ATP and related purines in inhibitory neurotransmission to the pig urinary bladder neck. British journal of pharmacology 20090801
Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin. PLoS neglected tropical diseases 20090801
Chemical communication between regenerating motor axons and Schwann cells in the growth pathway. The European journal of neuroscience 20090801
Advancing drug innovation for neglected diseases-criteria for lead progression. PLoS neglected tropical diseases 20090801
Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics. PLoS neglected tropical diseases 20090801
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates. The EMBO journal 20090722
P2X antagonists inhibit styryl dye entry into hair cells. Neuroscience 20090721
VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo. Glycoconjugate journal 20090701
Antiviral drug discovery: ten more compounds, and ten more stories (part B). Medicinal research reviews 20090701
Effects of vitamin E and sodium selenate on impaired contractile activity by bacterial lipopolysaccharide in the rat vas deferens. Naunyn-Schmiedeberg's archives of pharmacology 20090701
Angiotensin II-induced cyclooxygenase 2 expression in rat aorta vascular smooth muscle cells does not require heterotrimeric G protein activation. The Journal of pharmacology and experimental therapeutics 20090701
Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions. Journal of neurochemistry 20090701
A traveler with neurobrucellosis. Travel medicine and infectious disease 20090701
The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release. Purinergic signalling 20090601
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. The Journal of pharmacology and experimental therapeutics 20090601
Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases. Biochimica et biophysica acta 20090601
Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. Journal of hepatology 20090601
In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin. The Journal of antibiotics 20090601
Strategies to enhance the efficacy of intravescical therapy for non-muscle invasive bladder cancer. Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20090601
Involvement of P2Y receptors in pyridoxal-5'-phosphate-induced cardiac preconditioning. Fundamental & clinical pharmacology 20090601
Selective processing and metabolism of disease-causing mutant prion proteins. PLoS pathogens 20090601
Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo, Brazil) 20090601
Modulation of firing activity by ATP in dopamine neurons of the rat substantia nigra pars compacta. Neuroscience 20090519
Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices. Journal of neuroscience research 20090501
Cell density-dependent changes in intracellular Ca2+ mobilization via the P2Y2 receptor in rat bone marrow stromal cells. Journal of cellular physiology 20090501
Heparin-like effect contributes to the coagulopathy in patients with acute liver failure undergoing liver transplantation. Liver international : official journal of the International Association for the Study of the Liver 20090501
Ionotropic purinergic receptor P2X4 is involved in the regulation of chondrogenesis in chicken micromass cell cultures. Cell calcium 20090501
Extracellular ATP and P2 receptors are required for IL-8 to induce neutrophil migration. Cytokine 20090501
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain : a journal of neurology 20090501
Increase of intracellular Ca2+ by adenine and uracil nucleotides in human midbrain-derived neuronal progenitor cells. Cell calcium 20090501
Basic fibroblast growth factor increases the precursor pool of photoreceptors, but inhibits their differentiation and apoptosis in chicken retinal reaggregates. The European journal of neuroscience 20090501
Uridine-5'-triphosphate protects against hepatic- ischemic/reperfusion injury in mice. Transplantation 20090427
Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands. Glia 20090415
Central and peripheral nervous system toxicity of common chemotherapeutic agents. Cancer chemotherapy and pharmacology 20090401
Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090401
Suramin inhibits macrophage activation by human group IIA phospholipase A2, but does not affect bactericidal activity of the enzyme. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090401
Mapping of suramin binding sites on the group IIA human secreted phospholipase A2. Bioorganic chemistry 20090401
Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects. Biochemical pharmacology 20090401
Milrinone and theophylline act as lower oesophageal sphincter relaxing agents: a comparative pharmacodynamic study in the rabbit. Journal of veterinary pharmacology and therapeutics 20090401
CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity. Electrophoresis 20090401
Involvement of UTP in protection of cardiomyocytes from hypoxic stress. Canadian journal of physiology and pharmacology 20090401
Angiogenesis inhibition causes hypertension and placental dysfunction in a rat model of preeclampsia. Journal of hypertension 20090401
Regulation of adenosine 5'-triphosphate (ATP)-gated P2X(4) receptors on tracheal smooth muscle cells. Respiratory physiology & neurobiology 20090331
Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases). Purinergic signalling 20090301
Development of selective agonists and antagonists of P2Y receptors. Purinergic signalling 20090301
Mechanism of direct bicarbonate transport by the CFTR anion channel. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20090301
Ca(2+)-calmodulin can activate and inactivate cardiac ryanodine receptors. British journal of pharmacology 20090301
Structure and function of Pseudomonas aeruginosa protein PA1324 (21-170). Protein science : a publication of the Protein Society 20090301
Differential effect of neocuproine, a copper(I) chelator, on contractile activity in isolated ovariectomized non-pregnant rat, pregnant rat and pregnant human uterus. European journal of pharmacology 20090301
Investigation of the role of adrenergic and non-nitrergic, non-adrenergic neurotransmission in the sheep isolated internal anal sphincter. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090301
Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence. PLoS neglected tropical diseases 20090301
New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships. Bioorganic & medicinal chemistry 20090215
Hypergravity induces ATP release and actin reorganization via tyrosine phosphorylation and RhoA activation in bovine endothelial cells. Pflugers Archiv : European journal of physiology 20090201
Suramin promotes recovery from renal ischemia/reperfusion injury in mice. Kidney international 20090201
Native ion current coupled to purinergic activation via basal and mechanically induced ATP release in Xenopus follicles. Journal of cellular physiology 20090201
A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. American journal of physiology. Cell physiology 20090201
Enterostatin affects cyclic AMP and ERK signaling pathways to regulate Agouti-related protein (AgRP) expression. Peptides 20090201
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion. American journal of physiology. Gastrointestinal and liver physiology 20090201
Characterisation of ATP analogues to cross-link and label P2X receptors. Neuropharmacology 20090101
Characterization of a functional NTPDase in the endoplasmic reticulum of rat submandibular salivary gland. Physiological research 20090101
Ciliary body toxicity of subconjunctival suramin compared with mitomycin-C in the rabbit eye: determining the toxic concentration. Ophthalmic research 20090101
CrATP as a new inhibitor of ecto-ATPases of trypanosomatids. Parasitology 20090101
Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay. Molecular cancer therapeutics 20090101
A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper. BMC evolutionary biology 20090101
Use of protein tyrosine phosphatase inhibitors as promising targeted therapeutic drugs. Current medicinal chemistry 20090101
Alterations in gene expression induced by cyclic mechanical stress in trabecular meshwork cells. Molecular vision 20090101
Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria. Malaria journal 20090101
MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques. PloS one 20090101
Access to health care in relation to socioeconomic status in the Amazonian area of Peru. International journal for equity in health 20090101
Ecto-nucleoside triphosphate diphosphohydrolase 3 in the ventral and lateral hypothalamic area of female rats: morphological characterization and functional implications. Reproductive biology and endocrinology : RB&E 20090101
Biochemical and cellular characterization of lipophorin-midgut interaction in the hematophagous Panstrongylus megistus (Hemiptera: Reduviidae). Insect biochemistry and molecular biology 20090101
NTPDases in the neuroendocrine hypothalamus: possible energy regulators of the positive gonadotrophin feedback. Reproductive biology and endocrinology : RB&E 20090101
Calcium sensitivity for hypoxia in PGNs with PC-12 cells in co-culture. Advances in experimental medicine and biology 20090101
Translocation of neuronal nitric oxide synthase to the plasma membrane by ATP is mediated by P2X and P2Y receptors. Molecular pain 20090101
Chemotherapy of human african trypanosomiasis. Interdisciplinary perspectives on infectious diseases 20090101
Polysulfated/sulfonated compounds for the development of drugs at the crossroad of viral infection and oncogenesis. Current pharmaceutical design 20090101
New insights in the contribution of voltage-gated Na(v) channels to rat aorta contraction. PloS one 20090101
[Agents for the treatment of African sleeping sickness. Those developed in the last century]. Pharmazie in unserer Zeit 20090101
The exstrophy-epispadias complex. Orphanet journal of rare diseases 20090101
A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. Parasites & vectors 20090101
Brucellosis presenting as pyrexia of unknown origin in an international traveller: a case report. Cases journal 20090101
Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells. Cerebrospinal fluid research 20090101
Purinergic mechanosensory transduction and visceral pain. Molecular pain 20090101
Spontaneous Ca2+ oscillations via purinergic receptors elicit transient cell swelling in rat parotid ducts. The journal of medical investigation : JMI 20090101
La Mayson pour Distiller des Eaües at El Escorial: alchemy and medicine at the court of Philip II, 1556-1598. Medical history. Supplement 20090101
Capillary electrophoresis in drug discovery. Methods in molecular biology (Clifton, N.J.) 20090101
Aptamer-functionalized nano-biosensors. Sensors (Basel, Switzerland) 20090101
Antioxidant Activity and Total Phenolic and Flavonoid Contents of Hieracium pilosella L. Extracts. Sensors (Basel, Switzerland) 20090101
Role of TRP channels and NCX in mediating hypoxia-induced [Ca(2+)](i) elevation in PC12 cells. Respiratory physiology & neurobiology 20081231
In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica. Veterinary parasitology 20081220
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder. Brain research bulletin 20081216
New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives. Bioorganic & medicinal chemistry 20081215
Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer. British journal of cancer 20081209
Ca2+ oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (gammaPKC). Neuroscience letters 20081203
GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled by presynaptic purinergic receptors, modulating Ca2+ influx. Cell calcium 20081201
Purinergic-mediated Ca2+ influx in Dictyostelium discoideum. Cell calcium 20081201
Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth. The American journal of sports medicine 20081201
UTP and ATP increase extracellular signal-regulated kinase 1/2 phosphorylation in bovine chromaffin cells through epidermal growth factor receptor transactivation. Purinergic signalling 20081201
Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets. Purinergic signalling 20081201
ATP release from the human ureter on distension and P2X(3) receptor expression on suburothelial sensory nerves. Purinergic signalling 20081201
The burden of human African trypanosomiasis. PLoS neglected tropical diseases 20081201
Activity-dependent release of adenosine: a critical re-evaluation of mechanism. Current neuropharmacology 20081201
Alteration of cholinergic, purinergic and sensory neurotransmission in the mouse colon of food allergy model. Neuroscience letters 20081121
Nucleotide-induced Ca2+ signaling in sustentacular supporting cells of the olfactory epithelium. Glia 20081115
Sustained depolarization-induced propagation of [Ca2+]i oscillations in cultured DRG neurons: the involvement of extracellular ATP and P2Y receptor activation. Brain research 20081106
Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis. Molecules (Basel, Switzerland) 20081106
ATP activates P2x receptors and requires extracellular Ca(++) participation to modify outer hair cell nonlinear capacitance. Pflugers Archiv : European journal of physiology 20081101
Luminal ATP-induced contraction of rabbit pulmonary arteries and role of purinoceptors in the regulation of pulmonary arterial pressure. Pflugers Archiv : European journal of physiology 20081101
Volume-activated chloride channels in mice Leydig cells. Pflugers Archiv : European journal of physiology 20081101
Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain? Brain, behavior, and immunity 20081101
Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. Annals of oncology : official journal of the European Society for Medical Oncology 20081101
Corneal re-epithelialization stimulated by diadenosine polyphosphates recruits RhoA/ROCK and ERK1/2 pathways. Investigative ophthalmology & visual science 20081101
Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12 receptor. Journal of thrombosis and haemostasis : JTH 20081101
MDA-MB-231 produces ATP-mediated ICAM-1-dependent facilitation of the attachment of carcinoma cells to human lymphatic endothelial cells. American journal of physiology. Cell physiology 20081101
Extracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ release. American journal of physiology. Gastrointestinal and liver physiology 20081101
The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain. Journal of neurochemistry 20081101
Suramin: clinical uses and structure-activity relationships. Mini reviews in medicinal chemistry 20081101
Ectodomain lysines and suramin block of P2X1 receptors. The Journal of biological chemistry 20081031
A parasite cysteine protease is key to host protein degradation and iron acquisition. The Journal of biological chemistry 20081024
Endogenous ATP potentiates only vasopressin secretion from neurohypophysial terminals. Journal of cellular physiology 20081001
Transformation and actions of extracellular NADP(+) in the rat liver. Molecular and cellular biochemistry 20081001
High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+). European journal of applied physiology 20081001
Purinergic type 2 receptors at GABAergic synapses on ventral tegmental area dopamine neurons are targets for ethanol action. The Journal of pharmacology and experimental therapeutics 20081001
Structural characterization of myotoxic ecarpholin S from Echis carinatus venom. Biophysical journal 20081001
A universal method for fishing target proteins from mixtures of biomolecules using isothermal titration calorimetry. Protein science : a publication of the Protein Society 20081001
Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels. Molecular and cellular neurosciences 20081001
Long-term exposure to LPS enhances the rate of stimulated exocytosis and surfactant secretion in alveolar type II cells and upregulates P2Y2 receptor expression. American journal of physiology. Lung cellular and molecular physiology 20081001
Demonstration and partial characterization of ecto-ATPase in Balamuthia mandrillaris and its possible role in the host-cell interactions. Letters in applied microbiology 20081001
Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod. The American journal of pathology 20081001
Dual effect of ATP on glucose-induced insulin secretion in HIT-T15 cells. Pancreas 20081001
Extracellular ATP-induced NO production and its dependence on membrane Ca2+ flux in Salvia miltiorrhiza hairy roots. Journal of experimental botany 20081001
Angiogenesis: an improved in vitro biological system and automated image-based workflow to aid identification and characterization of angiogenesis and angiogenic modulators. Assay and drug development technologies 20081001
Ca2+ signaling in injured in situ endothelium of rat aorta. Cell calcium 20080901
Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor. American journal of respiratory cell and molecular biology 20080901
A dual system of intercellular calcium signaling in glial nets associated with lanceolate sensory endings in rat vibrissae. The Journal of comparative neurology 20080901
Adenine nucleotide changes in the remnant liver: An early signal for regeneration after partial hepatectomy. Hepatology (Baltimore, Md.) 20080901
CNS delivery via adsorptive transcytosis. The AAPS journal 20080901
Electrophysiological properties of a novel Ca(2+)-activated K(+) channel expressed in human osteoblasts. Calcified tissue international 20080901
Phase I/II trial of 5-fluorouracil and a noncytotoxic dose level of suramin in patients with metastatic renal cell carcinoma. Clinical genitourinary cancer 20080901
Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide. Journal of medicinal chemistry 20080814
Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, and biological activities. Journal of medicinal chemistry 20080814
Stimulation of alpha2-adrenoceptors suppresses excitatory synaptic transmission in the medial prefrontal cortex of rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080801
The counter and consultation room work explored in the Netherlands. Pharmacy world & science : PWS 20080801
P2X7 receptor as sensitive flow sensor for ERK activation in osteoblasts. Biochemical and biophysical research communications 20080801
Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity. Bioscience reports 20080801
Connexin45 is expressed in the juxtaglomerular apparatus and is involved in the regulation of renin secretion and blood pressure. American journal of physiology. Regulatory, integrative and comparative physiology 20080801
Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway. The Journal of physiology 20080801
Pharmacological properties of P2 receptors on rat otic parasympathetic ganglion neurons. Life sciences 20080801
Perspectives of antimony compounds in oncology. Acta pharmacologica Sinica 20080801
The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells. Medical science monitor : international medical journal of experimental and clinical research 20080801
Topically applied growth factors change skin cytoplasmic creatine kinase activity and distribution and produce abnormal keratinocyte differentiation in murine skin. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20080801
The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model. European journal of pharmacology 20080728
Minodronic acid, a third-generation bisphosphonate, antagonizes purinergic P2X(2/3) receptor function and exerts an analgesic effect in pain models. European journal of pharmacology 20080728
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. The Journal of biological chemistry 20080718
Intravesical treatments of bladder cancer: review. Pharmaceutical research 20080701
Acute inhibition of the betaine transporter by ATP and adenosine in renal MDCK cells. American journal of physiology. Renal physiology 20080701
Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: effect of simvastatin. Thrombosis and haemostasis 20080701
Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin. Cancer letters 20080628
Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium. Biology of reproduction 20080601
Connexin 40 and ATP-dependent intercellular calcium wave in renal glomerular endothelial cells. American journal of physiology. Regulatory, integrative and comparative physiology 20080601
Giardia lamblia: biochemical characterization of an ecto-ATPase activity. Experimental parasitology 20080601
Novel consequences of voltage-dependence to G-protein-coupled P2Y1 receptors. British journal of pharmacology 20080601
ATP induces guinea pig gallbladder smooth muscle excitability via the P2Y4 receptor and COX-1 activity. American journal of physiology. Gastrointestinal and liver physiology 20080601
The effects of suramin in prevention of peritendinous adhesions following flexor tendon injury in a chicken model. Orthopedics 20080601
Topical application of nucleotides increase lysozyme levels in tears. Clinical ophthalmology (Auckland, N.Z.) 20080601
Effect of phosphodiesterase type 4 inhibitor rolipram on cyclophosphamide-induced cystitis in rats. European journal of pharmacology 20080531
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. The Journal of biological chemistry 20080530
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer cell 20080506
H(2)O(2) modulates purinergic-dependent calcium signalling in osteoblast-like cells. Cell calcium 20080501
Glutamate release and synapsin-I phosphorylation induced by P2X7 receptors activation in cerebellar granule neurons. Neurochemistry international 20080501
Selective activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial growth factor-dependent mechanism. Diabetes 20080501
Leishmania amazonensis: effects of heat shock on ecto-ATPase activity. Experimental parasitology 20080501
Intravital microscopic characterization of suramin effects in an orthotopic immunocompetent rat model of pancreatic cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080501
Involvement of apical P2Y2 receptor-regulated CFTR activity in muscarinic stimulation of Cl(-) reabsorption in rat submandibular gland. American journal of physiology. Regulatory, integrative and comparative physiology 20080501
Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder. American journal of physiology. Regulatory, integrative and comparative physiology 20080501
Binding of liver derived, low density hepatitis C virus to human hepatoma cells. Journal of medical virology 20080501
Secreted protein acidic, rich in cysteine induces pulp cell migration via alphavbeta3 integrin and extracellular signal-regulated kinase. Oral diseases 20080501
Production of nitric oxide by carp (Cyprinus carpio L.) kidney leukocytes is regulated by cyclic 3',5'-adenosine monophosphate. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080501
Comparative effects of chemotherapeutic agents on the growth and survival of human adrenal carcinoma cells in culture. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080501
The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity. Cancer chemotherapy and pharmacology 20080401
Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery. American journal of physiology. Lung cellular and molecular physiology 20080401
A positive inotropic effect of ATP in the human cardiac atrium. American journal of physiology. Heart and circulatory physiology 20080401
Suramin and minocycline treatment of experimental African trypanososmiasis at an early stage of parasite brain invasion. Acta tropica 20080401
[Inhibitory effects of suramin on growth of transplanted lung adencarcinoma in mice and its mechanisms]. Ai zheng = Aizheng = Chinese journal of cancer 20080401
Of mice, cattle, and humans: the immunology and treatment of river blindness. PLoS neglected tropical diseases 20080401
P2Y receptor signaling regulates phenotype and IFN-alpha secretion of human plasmacytoid dendritic cells. Blood 20080315
Intracellular Ca2+ stores are essential for injury induced Ca2+ signaling and re-endothelialization. Journal of cellular physiology 20080301
Long-term modulation of tyrosine hydroxylase activity and expression by endothelin-1 and -3 in the rat anterior and posterior hypothalamus. American journal of physiology. Regulatory, integrative and comparative physiology 20080301
In vitro effects of suramin on Trypanosoma cruzi. International journal of antimicrobial agents 20080301
ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. British journal of pharmacology 20080301
Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression. Microbes and infection 20080301
Involvement of purinergic P2 receptors in experimental retinal neovascularization. Current eye research 20080301
Purinergic junctional transmission and propagation of calcium waves in cultured spinal cord microglial networks. Purinergic signalling 20080301
UCB Pharma research day-25 October 2007 'Glia-neuron interactions and purinergic receptors in neurological disorders'. Purinergic signalling 20080301
Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP. The Journal of membrane biology 20080301
The pharmacokinetics and interactions of ivermectin in humans--a mini-review. The AAPS journal 20080301
E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings. Life sciences 20080227
Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. Journal of medicinal chemistry 20080214
Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain. Molecular pharmacology 20080201
Characterization of calcium-independent purinergic receptor-mediated apoptosis in hormone-refractory prostate cancer. BJU international 20080201
Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue. British journal of pharmacology 20080201
Modulation of neurotransmitter release by P2X and P2Y receptors in the rat spinal cord. Neuropharmacology 20080201
[Extracorporeal Circulation; Historical aspects; Part II]. The Thoracic and cardiovascular surgeon 20080201
Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. The Journal of toxicological sciences 20080201
Eliminating human African trypanosomiasis: where do we stand and what comes next? PLoS medicine 20080201
Hypotensive effect of UDP on intraocular pressure in rabbits. European journal of pharmacology 20080128
Synaptic terminals from mice midbrain exhibit functional P2X7 receptor. Neuroscience 20080124
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus. Journal of medicinal chemistry 20080124
NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors. Cancer letters 20080118
A highly active and tolerable neoadjuvant regimen combining paclitaxel, carboplatin, 5-FU, and radiation therapy in patients with stage II and III esophageal cancer. Annals of surgical oncology 20080101
Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells. American journal of physiology. Renal physiology 20080101
FTY720 modulates human oligodendrocyte progenitor process extension and survival. Annals of neurology 20080101
Zymogen activation, inhibition, and ectodomain shedding of matriptase. Frontiers in bioscience : a journal and virtual library 20080101
Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study. Medical microbiology and immunology 20080101
Ability of suramin to antagonize the cardiotoxic and some enzymatic activities of Bothrops jararacussu venom. Toxicon : official journal of the International Society on Toxinology 20080101
Micro-electrode flux estimation confirms that the Solanum pimpinellifolium cu3 mutant still responds to systemin. Plant physiology 20080101
Quantitative image analysis of intra-tumoral bFGF level as a molecular marker of paclitaxel resistance. Journal of translational medicine 20080101
The history of African trypanosomiasis. Parasites & vectors 20080101
Diadenosine polyphosphates are selective vasoconstrictors in human coronary artery bypass grafts. Vascular pharmacology 20080101
The impact of the human DNA topoisomerase II C-terminal domain on activity. PloS one 20080101
Estimating the burden of rhodesiense sleeping sickness during an outbreak in Serere, eastern Uganda. BMC public health 20080101
OppA, the ecto-ATPase of Mycoplasma hominis induces ATP release and cell death in HeLa cells. BMC microbiology 20080101
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome research 20080101
Suramin induces and enhances apoptosis in a model of hyperoxia-induced oligodendrocyte injury. Neurotoxicity research 20080101
UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle. Parasites & vectors 20080101
Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Molecular vision 20080101
Use of data mining techniques to investigate disease risk classification as a proxy for compromised biosecurity of cattle herds in Wales. BMC veterinary research 20080101
Direct contact of platelets and their released products exert different effects on human dendritic cell maturation. BMC immunology 20080101
Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves. Frontiers in neuroengineering 20080101
Biochemical and structural investigations of Bothropstoxin-II, a myotoxic Asp49 phospholipase A2 from Bothrops jararacussu venom. Protein and peptide letters 20080101
Astrocytic Ca(2+) waves guide CNS growth cones to remote regions of neuronal activity. PloS one 20080101
African trypanosomiasis in two short-term Australian travelers to Malawi. Journal of travel medicine 20080101
Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip. Genome biology 20080101
Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells. Frontiers in neuroengineering 20080101
A novel bioluminescent protease assay using engineered firefly luciferase. Current chemical genomics 20080101
Synthetic nano-LDL with paclitaxel oleate as a targeted drug delivery vehicle for glioblastoma multiforme. Journal of controlled release : official journal of the Controlled Release Society 20071220
Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor. Journal of immunology (Baltimore, Md. : 1950) 20071215
Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release. Neuroscience 20071212
Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle. Molecular and cellular biochemistry 20071201
P2 purinoceptor-mediated cardioprotection in ischemic-reperfused mouse heart. The Journal of pharmacology and experimental therapeutics 20071201
P2Y2 nucleotide receptors inhibit trauma-induced death of astrocytic cells. Journal of neurochemistry 20071201
Duodenal brush border intestinal alkaline phosphatase activity affects bicarbonate secretion in rats. American journal of physiology. Gastrointestinal and liver physiology 20071201
Can we understand the clinical biology of gastric cancer and exploit it? May be, but it is a challenge! Annals of surgical oncology 20071201
Signal transduction pathways associated with ATP-induced proliferation of cell progenitors in the intact embryonic retina. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071201
Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans. Hepatology (Baltimore, Md.) 20071201
Mechanical and electrical responses modulated by excitation of inhibitory nerves during stimulation with high-potassium solutions in circular smooth muscle of the rabbit rectum. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20071201
Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308. The Journal of neuroscience : the official journal of the Society for Neuroscience 20071121
Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists. Biochemical pharmacology 20071115
Purinergic 2X1 receptors mediate endothelial dependent vasodilation to ATP. Molecular pharmacology 20071101
Downregulation of SGK1 by nucleotides in renal tubular epithelial cells. American journal of physiology. Renal physiology 20071101
Effect of suramin on the human pathogen Candida albicans: implications on the fungal development and virulence. FEMS immunology and medical microbiology 20071101
Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology 20071101
Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion. Gastroenterology 20071101
Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides. The Journal of physiology 20071015
Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma. International journal of cancer 20071001
Structure-activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (sirtuins). ChemMedChem 20071001
Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Trends in parasitology 20071001
Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida. Journal of natural products 20071001
Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents. Bioorganic & medicinal chemistry 20070915
Persisting benefits 12-18 months after discontinuation of pubertal metformin therapy in low birthweight girls. Clinical endocrinology 20070901
Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitis. The Journal of physiology 20070901
Lysophosphatidylserine increases membrane potentials in rat C6 glioma cells. Archives of pharmacal research 20070901
Adenosine A(1) receptor: Functional receptor-receptor interactions in the brain. Purinergic signalling 20070901
The role of ATP and adenosine in the brain under normoxic and ischemic conditions. Purinergic signalling 20070901
New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic signalling 20070901
Lack of evidence for direct phosphorylation of recombinantly expressed P2X(2) and P2X (3) receptors by protein kinase C. Purinergic signalling 20070901
Ectonucleotidases in Müller glial cells of the rodent retina: Involvement in inhibition of osmotic cell swelling. Purinergic signalling 20070901
Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation. Veterinary microbiology 20070831
Cisplatin cytotoxicity in organ of Corti-derived immortalized cells. Journal of cellular biochemistry 20070801
Inhibitory purinergic P2 receptor characterisation in rat distal colon. Neuropharmacology 20070801
Lysophospholipids regulate excitability and exocytosis in cultured bovine chromaffin cells. Journal of neurochemistry 20070801
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nature medicine 20070801
Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds. Journal of natural products 20070801
Effect of immunosuppressive and other drugs on the cortisol-cortisone shuttle in human kidney and liver. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070801
Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea. Hearing research 20070801
Immobilized P2X2 purinergic receptor stationary phase for chromatographic determination of pharmacological properties and drug screening. Journal of pharmaceutical and biomedical analysis 20070727
Role of cardiovascular nitric oxide system in C-type natriuretic peptide effects. Biochemical and biophysical research communications 20070720
ATP is the predominant sympathetic neurotransmitter in rat mesenteric arteries at high pressure. The Journal of physiology 20070715
Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain. American journal of physiology. Cell physiology 20070701
Modeling P2Y receptor-Ca2+ response coupling in taste cells. Biochimica et biophysica acta 20070701
Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron. Journal of the American Society of Nephrology : JASN 20070701
ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate. Clinical and experimental pharmacology & physiology 20070701
Hemodynamic responses elicited by systemic injections of flavin adenine dinucleotide in anesthetized rats. Journal of cardiovascular pharmacology 20070701
African trypanosomiasis in a British soldier. Military medicine 20070701
Binding of sperm proacrosin/beta-acrosin to zona pellucida glycoproteins is sulfate and stereodependent. Synthesis of a novel fertilization inhibitor. Developmental biology 20070615
Directed molecular screening for RecA ATPase inhibitors. Bioorganic & medicinal chemistry letters 20070615
P2 purinoceptor antagonists inhibit the non-adrenergic, non-cholinergic relaxation of the human colon in vitro. Neuroscience 20070615
Purinergic actions on neurons that modulate nociception in the rostral ventromedial medulla. Neuroscience 20070608
Suramin counteracts the haemostatic disturbances produced by Bothrops jararaca snake venom. Toxicon : official journal of the International Society on Toxinology 20070601
Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release. The Journal of physiology 20070601
Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia. American journal of physiology. Renal physiology 20070601
Treatment failure related to intrathecal immunoglobulin M (IgM) synthesis, cerebrospinal fluid IgM, and interleukin-10 in patients with hemolymphatic-stage sleeping sickness. Clinical and vaccine immunology : CVI 20070601
Extracellular ATP in activity-dependent remodeling of the neuromuscular junction. Developmental neurobiology 20070601
Roles of P2X receptors and Ca2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070601
Peripheral oxygen-sensing cells directly modulate the output of an identified respiratory central pattern generating neuron. The European journal of neuroscience 20070601
Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices. Purinergic signalling 20070601
P19 embryonal carcinoma cells as in vitro model for studying purinergic receptor expression and modulation of N-methyl-D-aspartate-glutamate and acetylcholine receptors during neuronal differentiation. Neuroscience 20070525
Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea. Hearing research 20070501
Smooth muscle and neural mechanisms contributing to the downregulation of neonatal rat spontaneous bladder contractions during postnatal development. American journal of physiology. Regulatory, integrative and comparative physiology 20070501
Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. Molecular pharmacology 20070501
Suprasternal gland secretion of male short-tailed opossum induces IP3 generation in the vomeronasal organ. Biochimica et biophysica acta 20070501
Mechanisms of G protein activation via the D2 dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation. British journal of pharmacology 20070501
Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon. British journal of pharmacology 20070501
Paracrine stimulation of vascular smooth muscle proliferation by diadenosine polyphosphates released from proximal tubule epithelial cells. Kidney international 20070501
Primary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human platelet. Journal of thrombosis and haemostasis : JTH 20070501
Air-exposed keratinocytes exhibited intracellular calcium oscillation. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20070501
Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. Life sciences 20070417
Carotid body chemosensory activity and ventilatory chemoreflexes in cats persist after combined cholinergic-purinergic block. Respiratory physiology & neurobiology 20070416
Effects of combined cholinergic-purinergic block upon cat carotid body chemoreceptors in vitro. Respiratory physiology & neurobiology 20070416
Mitogen-activated protein kinase signaling is involved in suramin-induced neurite outgrowth in a neuronal cell line. Biochemical and biophysical research communications 20070413
Incorporation of lycopene into chylomicron remnant-like particles inhibits their uptake by HepG2 cells. Life sciences 20070410
Purinergic control of the quail rectum: modulation of adenosine 5'-triphosphate-mediated contraction with acetylcholine. Research in veterinary science 20070401
Trypanosoma brucei brucei: biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities. Experimental parasitology 20070401
Role of p38 map kinase in glycine-induced hepatocyte resistance to hypoxic injury. Journal of hepatology 20070401
Regulation of extracellular UTP-activated Cl- current by P2Y-PLC-PKC signaling and ATP hydrolysis in mouse ventricular myocytes. The journal of physiological sciences : JPS 20070401
Extracellular ATP is involved in the induction of apoptosis in murine hematopoietic cells. Biological & pharmaceutical bulletin 20070401
Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. The Journal of membrane biology 20070401
Parasporin-1, a novel cytotoxic protein from Bacillus thuringiensis, induces Ca2+ influx and a sustained elevation of the cytoplasmic Ca2+ concentration in toxin-sensitive cells. The Journal of biological chemistry 20070309
Modulation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex by P2Y receptor activation. Cerebral cortex (New York, N.Y. : 1991) 20070301
Stimulation of purinergic receptors modulates chemokine expression in human keratinocytes. The Journal of investigative dermatology 20070301
Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists. American journal of physiology. Renal physiology 20070301
Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues. Toxicon : official journal of the International Society on Toxinology 20070301
Biochemical analysis of ecto-nucleotide pyrophosphatase phosphodiesterase activity in brain membranes indicates involvement of NPP1 isoenzyme in extracellular hydrolysis of diadenosine polyphosphates in central nervous system. Neurochemistry international 20070301
Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries. British journal of pharmacology 20070301
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin. Structure (London, England : 1993) 20070301
Trypanosoma evansi infections in Himalayan black bears (Selenarctos thibetanus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20070301
Nucleotide receptor signalling and the generation of reactive oxygen species. Purinergic signalling 20070301
Dominant role of betagamma subunits of G-proteins in oxytocin-evoked burst firing. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070221
Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytes. The Journal of investigative dermatology 20070201
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine. American journal of physiology. Gastrointestinal and liver physiology 20070201
Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C. Developmental biology 20070201
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat. Basic & clinical pharmacology & toxicology 20070201
Alterations of adenine nucleotide metabolism and function of blood platelets in patients with diabetes. Diabetes 20070201
Suramin inhibits not only tumor growth and metastasis but also angiogenesis in experimental pancreatic cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070201
Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladder. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070124
Synthetic nano-low density lipoprotein as targeted drug delivery vehicle for glioblastoma multiforme. International journal of pharmaceutics 20070102
Albumin-bound lipids induce free cytoplasmic calcium oscillations in human osteoblast-like cells. Cell biochemistry and function 20070101
Characterization of functional P2X(1) receptors in mouse megakaryocytes. Thrombosis research 20070101
Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro. American journal of physiology. Renal physiology 20070101
Suramin-restricted blood volume in the placenta of normal and diabetic rats is normalized by vitamin E treatment. Placenta 20070101
Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. American journal of physiology. Regulatory, integrative and comparative physiology 20070101
Differentiation-dependent alterations in the extracellular ATP-evoked calcium fluxes of cultured skeletal muscle cells from mice. Pflugers Archiv : European journal of physiology 20070101
Study on the cyclic GMP-dependency of relaxations to endogenous and exogenous nitric oxide in the mouse gastrointestinal tract. British journal of pharmacology 20070101
Aberrant Gi protein coupled receptor-mediated cell survival signaling in rheumatoid arthritis B cell lines. Frontiers in bioscience : a journal and virtual library 20070101
Different ways to antiangiogenesis by angiostatin and suramin, and quantitation of angiostatin-induced antiangiogenesis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20070101
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells. The international journal of biochemistry & cell biology 20070101
The anti-apoptotic activity of albumin for endothelium is mediated by a partially cryptic protein domain and reduced by inhibitors of G-coupled protein and PI-3 kinase, but is independent of radical scavenging or bound lipid. Journal of vascular research 20070101
Follicle stimulating hormone receptor (FSHR) antagonist and epithelial ovarian cancer (EOC). Journal of experimental therapeutics & oncology 20070101
Arthritis and pain. Future targets to control osteoarthritis pain. Arthritis research & therapy 20070101
Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP. BMC neuroscience 20070101
Structural and RNAi characterization of the German cockroach lipophorin receptor, and the evolutionary relationships of lipoprotein receptors. BMC molecular biology 20070101
Influence of IFN-gamma and its receptors in human breast cancer. BMC cancer 20070101
Divergent calcium signaling in RBCs from Tropidurus torquatus (Squamata--Tropiduridae) strengthen classification in lizard evolution. BMC physiology 20070101
Dynamic remodelling of synapses can occur in the absence of the parent cell body. BMC neuroscience 20070101
UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures. BMC plant biology 20070101
Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel. Molecular cancer 20070101
Fluctuations in the concentration of extracellular ATP synchronized with intracellular Ca(2+) oscillatory rhythm in cultured cardiac myocytes. Chronobiology international 20070101
Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS). In vivo (Athens, Greece) 20070101
New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents. Metal-based drugs 20070101
[Effect of medicinal preparations on the complement: inhibition of subcomponent C1q binding to a target]. Eksperimental'naia i klinicheskaia farmakologiia 20070101
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body. The open biochemistry journal 20070101
Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design. Drug target insights 20070101
Targeted brain tumor treatment-current perspectives. Drug target insights 20070101
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science (New York, N.Y.) 20061215
Purinergic nerves mediate the non-nitrergic relaxation of the human ileum in response to electrical field stimulation. Brain research bulletin 20061211
Involvement of stretch-activated cation channels in hypotonically induced insulin secretion in rat pancreatic beta-cells. American journal of physiology. Cell physiology 20061201
Different effects of ATP on the contractile activity of mice diaphragmatic and skeletal muscles. Neurochemistry international 20061201
ATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways. Stem cells (Dayton, Ohio) 20061201
Purinergic pathway suppresses the release of .NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. Journal of cellular physiology 20061201
Extracellular adenosine triphosphate protects oxidative stress-induced increase of p21(WAF1/Cip1) and p27(Kip1) expression in primary cultured renal proximal tubule cells: role of PI3K and Akt signaling. Journal of cellular physiology 20061201
Sphingosine-1-phosphate modulates both lipolysis and leptin production in differentiated rat white adipocytes. Endocrinology 20061201
NANC inhibitory neuromuscular transmission in the hamster distal colon. Pharmacological research 20061201
The minimal amyloid-forming fragment of the islet amyloid polypeptide is a glycolipid-binding domain. The FEBS journal 20061201
K+ channels involved in contractility of rabbit small intestine. Journal of physiology and biochemistry 20061201
Oxidized ATP decreases beta-actin expression and intracellular superoxide concentrations in RBA-2 type-2 astrocytes independently of P2X7 receptor. European journal of pharmacology 20061121
The co-treatments of vigabatrin and P2X receptor antagonists protect ischemic neuronal cell death in the gerbil hippocampus. Brain research 20061120
ATP and norepinephrine contributions to sympathetic vasoconstriction of tail artery are altered in streptozotocin-diabetic rats. American journal of physiology. Heart and circulatory physiology 20061101
Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner. Journal of cellular physiology 20061101
Gap junctional intercellular communication in bovine corneal endothelial cells. Experimental eye research 20061101
Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: involvement of MEK/ERK signalling. Journal of neurochemistry 20061101
Roles of P2 receptors in glial cells: focus on astrocytes. Purinergic signalling 20061101
Signal transduction events induced by extracellular guanosine 5' triphosphate in excitable cells. Purinergic signalling 20061101
Hypotonic shock stimulates ascorbate release from coronary artery endothelial cells by a Ca2+ -independent pathway. European journal of pharmacology 20061024
Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes. The Journal of biological chemistry 20061020
Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes. Bioorganic & medicinal chemistry letters 20061015
P2 purinergic receptors signal to STAT3 in astrocytes: Difference in STAT3 responses to P2Y and P2X receptor activation. Neuroscience 20061013
Treatment and follow-up of the first case of human trypanosomiasis caused by Trypanosoma evansi in India. Transactions of the Royal Society of Tropical Medicine and Hygiene 20061001
Bisphosphonates activate nucleotide receptors signaling and induce the expression of Hsp90 in osteoblast-like cell lines. Bone 20061001
Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway. Journal of cellular physiology 20061001
PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo. Cancer research 20061001
Presynaptic inhibition of spontaneous acetylcholine release mediated by P2Y receptors at the mouse neuromuscular junction. Neuroscience 20060929
Desensitization of somatostatin-induced inhibition of low extracellular magnesium concentration-induced calcium spikes in cultured rat hippocampal neurons. Brain research 20060921
Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells. Toxicology and applied pharmacology 20060901
Reactive blue 2, an antagonist of rat P2Y4, increases K+ secretion in rat cochlea strial marginal cells. Hearing research 20060901
A woman with fever and rash after African safari. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060901
Hypotonic stress activates BK channels in clonal kidney cells via purinergic receptors, presumably of the P2Y subtype. Acta physiologica (Oxford, England) 20060901
Biochemical characterization of suramin as a selective inhibitor for the PKA-mediated phosphorylation of HBV core protein in vitro. Biological & pharmaceutical bulletin 20060901
P2Y receptor-mediated excitation in the posterior hypothalamus. The European journal of neuroscience 20060901
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacological reviews 20060901
A Gambian infant with fever and an unexpected blood film. PLoS medicine 20060901
African trypanosomiasis in a British soldier. Journal of the Royal Army Medical Corps 20060901
Plant responses to extracellular nucleotides: Cellular processes and biological effects. Purinergic signalling 20060901
Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks. Purinergic signalling 20060901
Increased 5-HT(3)-mediated signalling in pelvic afferent neurons from mice deficient in P2X(2) and/or P2X (3) receptor subunits. Purinergic signalling 20060901
Excitatory effect of ATP on rat area postrema neurons. Purinergic signalling 20060901
Altered neurogenic and mechanical responses to acetylcholine, ATP and substance P in detrusor from rat with outlet obstruction. Life sciences 20060822
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes. European journal of pharmacology 20060814
Distinct mono- and dinucleotide-specific P2Y receptors in A549 lung epithelial cells: different control of arachidonic acid release and nitric oxide synthase expression. European journal of pharmacology 20060814
Activation of Src/kinase/phospholipase C/mitogen-activated protein kinase and induction of neurite expression by ATP, independent of nerve growth factor. Neuroscience 20060811
Defective nitric oxide-dependent, deaminative cleavage of glypican-1 heparan sulfate in Niemann-Pick C1 fibroblasts. Glycobiology 20060801
Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. PLoS biology 20060801
Effects of potassium channel modulators on human detrusor smooth muscle myogenic phasic contractile activity: potential therapeutic targets for overactive bladder. Urology 20060801
Role of ATP in DNA synthesis of renal proximal tubule cells: involvement of calcium, MAPKs, and CDKs. American journal of physiology. Renal physiology 20060701
Effects of hypo-osmotic stress on ATP release in isolated turbot (Scophthalmus maximus) hepatocytes. Biology of the cell 20060701
Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats. British journal of pharmacology 20060701
ATP stimulates interleukin-6 production via P2Y receptors in human HaCaT keratinocytes. European journal of pharmacology 20060701
Increased expression of insulin-like growth factor i is associated with Ara-C resistance in leukemia. The Tohoku journal of experimental medicine 20060701
[Pharmacological means to prevent secondary cataract]. Klinische Monatsblatter fur Augenheilkunde 20060701
Investigation of the mechanism for the relaxation of rat duodenum mediated via M1 muscarinic receptors. Autonomic & autacoid pharmacology 20060701
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochemical pharmacology 20060628
Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacology & therapeutics 20060601
Heterogeneous response of microvascular endothelial cells to shear stress. American journal of physiology. Heart and circulatory physiology 20060601
The effect of TAO expression on PCD-like phenomenon development and drug resistance in Trypanosoma brucei. Parasitology international 20060601
Characterization of an ecto-ATPase activity in Fonsecaea pedrosoi. Archives of microbiology 20060601
The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups. Molecular pharmacology 20060601
Nontoxic suramin as a chemosensitizer in patients: dosing nomogram development. Pharmaceutical research 20060601
Activities and accomplishments of the cancer and leukemia group B genitourinary committee. Clinical cancer research : an official journal of the American Association for Cancer Research 20060601
The antimicrobial peptide LL-37 enhances IL-8 release by human airway smooth muscle cells. The Journal of allergy and clinical immunology 20060601
Copper excess triggers phospholipase D activity in wheat roots. Phytochemistry 20060601
Reciprocal inhibition of Cd(2+) and Ca(2+) uptake in human intestinal crypt cells for voltage-independent Zn-activated pathways. Biochimica et biophysica acta 20060601
Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic signalling 20060601
Suramin-induced reciprocal changes in glucose and lactate synthesis in renal tubules contribute to its hyperglycaemic action. European journal of pharmacology 20060510
Regulation of expression of early growth response transcription factors in rat primary cortical neurons by extracellular ATP. Brain research 20060509
Biochemical and immunochemical characterisation of human diadenosine triphosphatase provides evidence for its identification with the tumour suppressor Fhit protein. Biochimie 20060501
Inhibition by suramin of protein synthesis in vitro. Ribosomes as the target of the drug. Biochimie 20060501
ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling. The Journal of investigative dermatology 20060501
A phosphatidylinositol transfer protein alpha-dependent survival factor protects cultured primary neurons against serum deprivation-induced cell death. Journal of neurochemistry 20060501
Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man. Journal of neurology, neurosurgery, and psychiatry 20060501
[Systemic therapy of malignant adrenal tumors]. Der Urologe. Ausg. A 20060501
Effect of suramin on trypomastigote forms of Trypanosoma cruzi: changes on cell motility and on the ultrastructure of the flagellum-cell body attachment region. Acta tropica 20060501
Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei. Chemical biology & drug design 20060501
Anti-HIV-1 protease- and HIV-1 integrase activities of Thai medicinal plants known as Hua-Khao-Yen. Journal of ethnopharmacology 20060421
Role of nitric oxide on ATP-induced Ca2+ signaling in outer hair cells of the guinea pig cochlea. Brain research 20060407
Schwann cells in rat vascular autonomic nerves activated via purinergic receptors. Neuroreport 20060403
P2X receptors in mouse Leydig cells. American journal of physiology. Cell physiology 20060401
Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway. Blood 20060401
Potential inhibitors of chemokine function: analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry. Journal of the American Society for Mass Spectrometry 20060401
[Effects of suramin in combination with cisplatin on growth and metastasis of lung adenocarcinoma xenografts in mice]. Ai zheng = Aizheng = Chinese journal of cancer 20060401
Role of protein kinase C, G-protein coupled receptors, and calcium flux during metamorphosis of the sea urchin Strongylocentrotus purpuratus. The Biological bulletin 20060401
Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm. Bulletin of experimental biology and medicine 20060401
Evidence for CEA release from human colon cancer cells by an endogenous GPI-PLD enzyme. Cancer letters 20060328
Probable role of spinal purinoceptors in the analgesic effect of Trigonella foenum (TFG) leaves extract. Journal of ethnopharmacology 20060308
Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain research 20060303
Feed forward cycle of hypotonic stress-induced ATP release, purinergic receptor activation, and growth stimulation of prostate cancer cells. The Journal of biological chemistry 20060303
Extracellular ATP stimulates NO production in rat thick ascending limb. Hypertension (Dallas, Tex. : 1979) 20060301
Ecto-nucleotide pyrophosphatase/phosphodiesterase as part of a multiple system for nucleotide hydrolysis by platelets from rats: kinetic characterization and biochemical properties. Platelets 20060301
Cosignaling of adenosine and adenosine triphosphate in hypobaric hypoxia-induced hypothermia. American journal of physiology. Regulatory, integrative and comparative physiology 20060301
Influence of angiogenesis inhibitors on endothelial cell morphology in vitro. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060301
High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro. FEBS letters 20060206
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control. Neuropharmacology 20060201
Trypanosoma rangeli: characterization of a Mg-dependent ecto ATP-diphosphohydrolase activity. Experimental parasitology 20060201
Extracellular ATP-stimulated current in wild-type and P2X4 receptor transgenic mouse ventricular myocytes: implications for a cardiac physiologic role of P2X4 receptors. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. Tropical medicine & international health : TM & IH 20060201
Activation of P2Y receptor enhances high-molecular compound absorption from rat ileum. The Journal of pharmacy and pharmacology 20060201
Understanding the mechanism of the antimitogenic activity of suramin. Biochemistry 20060124
Purinergic receptor antagonists inhibit odorant-induced heat shock protein 25 induction in mouse olfactory epithelium. Glia 20060115
Inhibition mechanism of the recombinant rat P2X(2) receptor in glial cells by suramin and TNP-ATP. Biochemistry 20060110
Suramin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of NF-kappaB activity. Cytokine 20060107
Orchitis as an unusual manifestation of human African trypanosomiasis. The Journal of infection 20060101
Augmented extracellular ATP signaling in bladder urothelial cells from patients with interstitial cystitis. American journal of physiology. Cell physiology 20060101
Effect of ATP on preadipocyte migration and adipocyte differentiation by activating P2Y receptors in 3T3-L1 cells. The Biochemical journal 20060101
Enhanced neurally evoked responses and inhibition of norepinephrine reuptake in rat mesenteric arteries after spinal transection. American journal of physiology. Heart and circulatory physiology 20060101
Purinoceptors are involved in the induction of an osmolyte permeability in malaria-infected and oxidized human erythrocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060101
The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells. British journal of pharmacology 20060101
Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses. Antiviral research 20060101
Diversity of Cl(-) channels. Cellular and molecular life sciences : CMLS 20060101
Microglial morphology and its transformation after challenge by extracellular ATP in vitro. Journal of neuroscience research 20060101
Ca2+-mediated ascorbate release from coronary artery endothelial cells. British journal of pharmacology 20060101
Spontaneous oscillation and mechanically induced calcium waves in chondrocytes. Cell biochemistry and function 20060101
Ecto-nucleotidase activities in the fat body of Rhodnius prolixus. Archives of insect biochemistry and physiology 20060101
Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities. Journal of natural products 20060101
Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors. BMC microbiology 20060101
Circumvention of camptothecin-induced resistance during the adaptive cellular stress response. Anticancer research 20060101
Putting theory into practice: James Black, receptor theory and the development of the beta-blockers at ICI, 1958-1978. Medical history 20060101
Depression of presynaptic excitation by the activation of vanilloid receptor 1 in the rat spinal dorsal horn revealed by optical imaging. Molecular pain 20060101
A rare case of human trypanosomiasis caused by Trypanosoma evansi. Indian journal of medical microbiology 20060101
Purinergic substances promote murine keratinocyte proliferation and enhance impaired wound healing in mice. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101
Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group. BMC cancer 20060101
A purinergic dialogue between glia and neurons in the retina. Novartis Foundation symposium 20060101
In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. Kinetoplastid biology and disease 20060101
The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6+/- mouse model of epithelial wound-healing delay. BMC biology 20060101
Osmoregulation of taurine efflux from cultured human breast cancer cells: comparison with volume activated Cl- efflux and regulation by extracellular ATP. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Green fluorescent protein as a reporter of prion protein folding. Virology journal 20060101
Phase I evaluation of low-dose suramin as chemosensitizer of doxorubicin in dogs with naturally occurring cancers. Journal of veterinary internal medicine 20060101
Targeting of toxic compounds to the trypanosome's interior. Advances in parasitology 20060101
Cooperative therapeutic effects of herpes simplex virus thymidine kinase gene/ganciclovir system and chemotherapeutic agents on prostate cancer in vitro. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101
Nebivovol and carvedilol induce NO-dependent coronary vasodilatation that is unlikely to be mediated by extracellular ATP in the isolated guinea pig heart. Pharmacological reports : PR 20060101
Synthesis, characterization, and cytotoxic activity of new lanthanum(III) complexes of bis-coumarins. Bioinorganic chemistry and applications 20060101
The effect of P2X receptor activity on GABAA receptor-mediated inhibition in the gerbil hippocampus. Brain research 20051214
Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog. The Journal of pharmacology and experimental therapeutics 20051201
Neurally released ATP mediates endothelium-dependent hyperpolarization in the circular smooth muscle cells of chicken anterior mesenteric artery. British journal of pharmacology 20051201
Extracellular ATP determines 11beta-hydroxysteroid dehydrogenase type 2 activity via purinergic receptors. Journal of the American Society of Nephrology : JASN 20051201
ATP- and adenosine-induced relaxation of the smooth muscle of the pig urethra. BJU international 20051201
A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction. Purinergic signalling 20051201
ADPbetaS evokes microglia activation in the rabbit retina in vivo. Purinergic signalling 20051201
Interactions of charged ligands with beta(2)-microglobulin conformers in affinity capillary electrophoresis. Biochimica et biophysica acta 20051110
Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. Journal of medicinal chemistry 20051103
ATP stimulates Na+-glucose cotransporter activity via cAMP and p38 MAPK in renal proximal tubule cells. American journal of physiology. Cell physiology 20051101
Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro. British journal of pharmacology 20051101
Search of ligands for the amyloidogenic protein beta2-microglobulin by capillary electrophoresis and other techniques. Electrophoresis 20051101
Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication. Journal of cell science 20051101
Molecular identification of a malaria merozoite surface sheddase. PLoS pathogens 20051101
Role of purinoceptors in cardiac function in rats during ontogeny. Bulletin of experimental biology and medicine 20051101
Effect of adenosine triphosphate on phosphate uptake in renal proximal tubule cells: involvement of PKC and p38 MAPK. Journal of cellular physiology 20051001
Neocuproine, a copper (I) chelator, potentiates purinergic component of vas deferens contractions elicited by electrical field stimulation. Pharmacology 20051001
Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676. British journal of pharmacology 20051001
Apoptosis modulates protective immunity to the pathogenic fungus Histoplasma capsulatum. The Journal of clinical investigation 20051001
Differential regulation of ca(2+) signaling and membrane trafficking by multiple p2 receptors in brown adipocytes. The Journal of membrane biology 20051001
Involvement of nitric oxide pathways in short term modulation of tyrosine hydroxylase activity by endothelins 1 and 3 in the rat anterior hypothalamus. Biochemical and biophysical research communications 20050902
Intrinsic inhibitory innervation of the stomach. British journal of pharmacology 20050901
Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors. Journal of neurophysiology 20050901
P2 receptor blockade attenuates fever and cytokine responses induced by lipopolysaccharide in rats. British journal of pharmacology 20050901
ATP elicits inward currents in isolated vasopressinergic neurohypophysial terminals via P2X2 and P2X3 receptors. Pflugers Archiv : European journal of physiology 20050901
Pharmacological characterization of nucleotide P2Y receptors on endothelial cells of the mouse aorta. British journal of pharmacology 20050901
Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain. British journal of pharmacology 20050901
Human trypanosomiasis caused by Trypanosoma evansi in India: the first case report. The American journal of tropical medicine and hygiene 20050901
[Anti-angiogenesis treatment for brain tumors--present and future]. Nihon rinsho. Japanese journal of clinical medicine 20050901
Possible role of sildenafil in inhibiting rat vas deferens contractions by influencing the purinergic system. International journal of urology : official journal of the Japanese Urological Association 20050901
Trypanosomiasis control, Democratic Republic of Congo, 1993-2003. Emerging infectious diseases 20050901
Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS. Purinergic signalling 20050901
P2X(7) receptor: Death or life? Purinergic signalling 20050901
Identification of a tyrosine residue responsible for N-acetylimidazole-induced increase of activity of ecto-nucleoside triphosphate diphosphohydrolase 3. Purinergic signalling 20050901
Structural basis for antagonism by suramin of heparin binding to vaccinia complement protein. Biochemistry 20050816
On the nature and origin of DNA strand breaks in elongating spermatids. Biology of reproduction 20050801
Ligament cells stretch-adapted on a microgrooved substrate increase intercellular communication in response to a mechanical stimulus. Journal of biomechanics 20050801
The morphogenesis of the exstrophy-epispadias complex: a new concept based on observations made in early embryonic cases of cloacal exstrophy. Anatomy and embryology 20050801
Effect of chronic wound exudates and MMP-2/-9 inhibitor on angiogenesis in vitro. Plastic and reconstructive surgery 20050801
Prognostic significance of plasma chromogranin a levels in patients with hormone-refractory prostate cancer treated in Cancer and Leukemia Group B 9480 study. Urology 20050801
Co-activation of P2Y2 receptor and TRPV channel by ATP: implications for ATP induced pain. Cellular and molecular neurobiology 20050801
Lysophosphatidylserine stimulates leukemic cells but not normal leukocytes. Biochemical and biophysical research communications 20050729
Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma. Biochemical and biophysical research communications 20050722
Inhibition of myotoxic activity of Bothrops asper myotoxin II by the anti-trypanosomal drug suramin. Journal of molecular biology 20050715
Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. Free radical biology & medicine 20050715
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706
The mechanism by which ethanol inhibits rat P2X4 receptors is altered by mutation of histidine 241. British journal of pharmacology 20050701
ATP regulation of ciliary beat frequency in rat tracheal and distal airway epithelium. Experimental physiology 20050701
Suramin promotes proliferation and scattering of renal epithelial cells. The Journal of pharmacology and experimental therapeutics 20050701
Suramin and disulfonated stilbene derivatives stimulate the Ca2+-induced Ca2+ -release mechanism in A7r5 cells. Molecular pharmacology 20050701
LeRALF, a plant peptide that regulates root growth and development, specifically binds to 25 and 120 kDa cell surface membrane proteins of Lycopersicon peruvianum. Planta 20050701
Low dose suramin as a chemosensitizer of bladder cancer to mitomycin C. The Journal of urology 20050701
Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa. Cell biology international 20050701
Nontoxic suramin treatments enhance docetaxel activity in chemotherapy-pretreated non-small cell lung xenograft tumors. Pharmaceutical research 20050701
Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cbeta-dependent Ca2+ transient. Alcoholism, clinical and experimental research 20050701
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding. Canadian journal of physiology and pharmacology 20050701
H2O2 induces paracellular permeability of porcine brain-derived microvascular endothelial cells by activation of the p44/42 MAP kinase pathway. European journal of cell biology 20050701
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range. Naunyn-Schmiedeberg's archives of pharmacology 20050701
Inhibition of proteinase 3 (PR3) by suramin and fetal calf serum (FCS): effect of PR3 and suramin on Chinese hamster ovary cells (CHO-cells). Pakistan journal of pharmaceutical sciences 20050701
Cancer biology and hormesis: comments on Calabrese (2005). Critical reviews in toxicology 20050701
Mitogenic signaling by lysophosphatidic acid (LPA) involves Galpha12. Oncogene 20050630
Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma. British journal of cancer 20050620
Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. The Journal of biological chemistry 20050617
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells. The Biochemical journal 20050615
The effect of a hyposmotic shock and purinergic agonists on K+(Rb+) efflux from cultured human breast cancer cells. Biochimica et biophysica acta 20050615
Calcium increases in retinal glial cells evoked by light-induced neuronal activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050608
ATP released via gap junction hemichannels from the pigment epithelium regulates neural retinal progenitor proliferation. Neuron 20050602
Purinergic modulation of cardiovascular function in the rat locus coeruleus. British journal of pharmacology 20050601
Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells. The Journal of endocrinology 20050601
Trypanosomiasis relapse after melarsoprol therapy, Democratic Republic of Congo, 1982-2001. Emerging infectious diseases 20050601
Evidence for the existence of P2Y1,2,4 receptor subtypes in HEK-293 cells: reactivation of P2Y1 receptors after repetitive agonist application. Naunyn-Schmiedeberg's archives of pharmacology 20050601
Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP. Purinergic signalling 20050601
High zinc sensitivity and pore formation in an invertebrate P2X receptor. Biochimica et biophysica acta 20050520
Reactive oxygen species contribute to the presynaptic action of extracellular ATP at the frog neuromuscular junction. The Journal of physiology 20050515
Varicosity-Schwann cell interactions mediated by ATP in the mouse vas deferens. Journal of neurophysiology 20050501
Renovascular effects of sympathetic cotransmitters ATP and NPY are age-dependent in spontaneously hypertensive rats. Cardiovascular research 20050501
Placental dysfunction in Suramin-treated rats--a new model for pre-eclampsia. Placenta 20050501
The catalytically active serine protease domain of human complement factor I. Biochemistry 20050426
Evidence for the presence of P2y and P2x receptors with different functions in mouse stomach. European journal of pharmacology 20050418
ATP-stimulated ANP release through P1 receptor subtype. Regulatory peptides 20050415
Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress. Biochemical pharmacology 20050415
Purinergic regulation of cholangiocyte secretion: identification of a novel role for P2X receptors. American journal of physiology. Gastrointestinal and liver physiology 20050401
Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells. American journal of physiology. Cell physiology 20050401
Suramin disrupts receptor-G protein coupling by blocking association of G protein alpha and betagamma subunits. The Journal of pharmacology and experimental therapeutics 20050401
Elementary purinergic Ca2+ transients evoked by nerve stimulation in rat urinary bladder smooth muscle. The Journal of physiology 20050401
Effects of diadenosine polyphosphates on glomerular volume. British journal of pharmacology 20050401
Keratinocyte growth factor-1 expression in healthy and diseased human periodontal tissues. Journal of periodontal research 20050401
Placental dysfunction in Suramin-treated rats: impact of maternal diabetes and effects of antioxidative treatment. Journal of the Society for Gynecologic Investigation 20050401
Clinical trials in metastatic prostate cancer--has there been real progress in the past decade? European journal of cancer (Oxford, England : 1990) 20050401
Robust quantification of in vitro angiogenesis through image analysis. IEEE transactions on medical imaging 20050401
G-protein coupled activation of potassium channels by endogenous neuropeptides in snail neurons. The European journal of neuroscience 20050401
Biological inactivation and impaired detection of IL-10 by suramin. Journal of immunological methods 20050401
Epidermal growth factor receptor double targeting by a tyrosine kinase inhibitor (Iressa) and a monoclonal antibody (Cetuximab). Impact on cell growth and molecular factors. British journal of cancer 20050328
Excitatory purinergic neurotransmission in smooth muscle of guinea-pig [corrected] taenia caeci. The Journal of physiology 20050315
Effect of neocuproine, a copper(i) chelator, on rat bladder function. The Journal of pharmacology and experimental therapeutics 20050301
An electrophysiological study of excitatory purinergic neuromuscular transmission in longitudinal smooth muscle of chicken anterior mesenteric artery. British journal of pharmacology 20050301
Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist. Neuropharmacology 20050301
Antiprotozoal activities of new bicyclo[2.2.2]octan-2-imines and esters of bicyclo[2.2.2]octan-2-ols. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050301
Mechanisms of ATP action on motor nerve terminals at the frog neuromuscular junction. The European journal of neuroscience 20050301
Purinergic mechanisms of the nucleus of the solitary tract and neural cardiovascular control. Neurological research 20050301
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle. European journal of pharmacology 20050221
Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochemical pharmacology 20050215
Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound. British journal of cancer 20050214
Properties of presynaptic P2X7-like receptors at the neuromuscular junction. Brain research 20050209
C-terminal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation. The Biochemical journal 20050201
Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050201
Selective release of ATP from sympathetic nerves of rat vas deferens by the toxin TsTX-I from Brazilian scorpion Tityus serrulatus. British journal of pharmacology 20050201
Biochemical and functional evidence for heteromeric assembly of P2X1 and P2X4 subunits. Journal of neurochemistry 20050201
Purinergic modulation of pacemaker Ca2+ activity in interstitial cells of Cajal. Neuropharmacology 20050201
Localization of intracellular calcium release in cells injured by venom from the ectoparasitoid Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae) and dependence of calcium mobilization on G-protein activation. Journal of insect physiology 20050201
Suramin interacts with RANK and inhibits RANKL-induced osteoclast differentiation. Bone 20050201
[The inhibiting effects of suramin on bFGF induced proliferation of cultured human RPE cells]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20050201
Role of ERK in hydrogen peroxide-induced cell death of human glioma cells. Neurochemical research 20050201
Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5) activity in human lymphocytes. Biochimica et biophysica acta 20050118
Chlorambucil and lomustine (CL56) in absolute hormone refractory prostate cancer: re-induction of endocrine sensitivity an unexpected finding. British journal of cancer 20050117
ATP-stimulated interleukin-6 synthesis through P2Y receptors on human osteoblasts. Biochemical and biophysical research communications 20050114
[ERK1/2 and p38 kinases are important regulators in P2Y receptor-mediated prostate cancer invasion]. Zhonghua yi xue za zhi 20050112
Hydrogen peroxide-induced extracellular signal-regulated kinase activation in cultured feline ileal smooth muscle cells. The Journal of pharmacology and experimental therapeutics 20050101
Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells. American journal of physiology. Renal physiology 20050101
Evaluation of the mouse prostate as a suitable model for the study of human prostate function. Journal of pharmacological and toxicological methods 20050101
The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury. The American journal of sports medicine 20050101
ATP-dependent paracrine intercellular communication in cultured bovine corneal endothelial cells. Investigative ophthalmology & visual science 20050101
Interaction between mGluR8 and calcium channels in photoreceptors is sensitive to pertussis toxin and occurs via G protein betagamma subunit signaling. Investigative ophthalmology & visual science 20050101
Secretion of ATP from Schwann cells in response to uridine triphosphate. The European journal of neuroscience 20050101
Antiprotozoal compounds from Psorothamnus polydenius. Journal of natural products 20050101
Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28). Virology journal 20050101
A P2X receptor-mediated nociceptive afferent pathway to lamina I of the spinal cord. Molecular pain 20050101
Combination chemotherapy with docetaxel, estramustine and suramin for hormone refractory prostate cancer. Urologic oncology 20050101
P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia. International journal of immunopathology and pharmacology 20050101
Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]. Neuroscience 20050101
New agents in intravesical chemotherapy of superficial bladder cancer. Scandinavian journal of urology and nephrology 20050101
Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle. Filaria journal 20050101
Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions. BMC pharmacology 20050101
Multiple P2Y receptors couple to calcium-dependent, chloride channels in smooth muscle cells of the rat pulmonary artery. Respiratory research 20050101
Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium. Cell communication and signaling : CCS 20050101
Neuroprotective effects of inhibiting N-methyl-D-aspartate receptors, P2X receptors and the mitogen-activated protein kinase cascade: a quantitative analysis in organotypical hippocampal slice cultures subjected to oxygen and glucose deprivation. Neuroscience 20050101
[The calmodulin inhibitor R24571 induces a short-term Ca2+ entry and a pulse-like secretion of ATP in Ehrlich ascites tumor cells]. Biofizika 20050101
Modulation of adenylyl cyclase activity in young and adult rat brain cortex. Identification of suramin as a direct inhibitor of adenylyl cyclase. Journal of cellular and molecular medicine 20050101
Heterogeneous cytoplasmic calcium response in microvascular endothelial cells. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101
[Effects of purinergic analogues on spontaneous contraction and electrical activities of gastric antral circular muscle in guinea-pig]. Sheng li xue bao : [Acta physiologica Sinica] 20041225
ATP inhibits pump activity of lymph vessels via adenosine A1 receptor-mediated involvement of NO- and ATP-sensitive K+ channels. American journal of physiology. Heart and circulatory physiology 20041201
Divergent effects of the purinoceptor antagonists suramin and pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) (PPNDS) on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Molecular pharmacology 20041201
Water induces autocrine stimulation of tumor cell killing through ATP release and P2 receptor binding. Cell death and differentiation 20041201
Chronic decentralization potentiates neurovascular transmission in the isolated rat tail artery, mimicking the effects of spinal transection. The Journal of physiology 20041201
Drug-induced corneal complications. Current opinion in ophthalmology 20041201
Congenital trypanosomiasis. Journal of tropical pediatrics 20041201
Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig. Neuropharmacology 20041201
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels. The European journal of neuroscience 20041201
ATP and ADP hydrolysis in the kidney and liver of fish, chickens and rats. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20041201
Evaluation of combination chemotherapy: integration of nonlinear regression, curve shift, isobologram, and combination index analyses. Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA2 from Bothrops asper venom. Biochimica et biophysica acta 20041201
P2Y receptors and pain transmission. Purinergic signalling 20041201
P2 receptors are involved in the mediation of motivation-related behavior. Purinergic signalling 20041201
Regulation of neuronal ion channels via P2Y receptors. Purinergic signalling 20041201
GPR80/99, proposed to be the P2Y(15) receptor activated by adenosine and AMP, is not a P2Y receptor. Purinergic signalling 20041201
Quality of life impact of three different doses of suramin in patients with metastatic hormone-refractory prostate carcinoma: results of Intergroup O159/Cancer and Leukemia Group B 9480. Cancer 20041115
Cardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats. American journal of physiology. Regulatory, integrative and comparative physiology 20041101
Mechanisms of the ATP potentiation of hyposmotic taurine release in Swiss 3T3 fibroblasts. Pflugers Archiv : European journal of physiology 20041101
Hypo-osmotic potentiation of acetylcholine-stimulated ciliary beat frequency through ATP release in rat tracheal ciliary cells. Experimental physiology 20041101
Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells. British journal of pharmacology 20041101
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia. British journal of pharmacology 20041101
Positive inotropic and sustained anti-beta-adrenergic effect of diadenosine pentaphosphate in human and guinea pig hearts. Role of dinucleotide receptors and adenosine receptors. Acta physiologica Scandinavica 20041101
Chemotherapy-induced peripheral neurotoxicity. Expert opinion on drug safety 20041101
A murine model of ex vivo angiogenesis using aortic disks grown in fibrin clot. Microvascular research 20041101
Evidence for an apamin-sensitive, but not purinergic, component in the nonadrenergic noncholinergic relaxation of the rat gastric fundus. British journal of pharmacology 20041101
Ecto-ATPases of clinical and non-clinical isolates of Acanthamoeba. Microbial pathogenesis 20041101
Suramin as a chemosensitizer: oral pharmacokinetics in rats. Pharmaceutical research 20041101
Suramin interaction with human alpha-thrombin: inhibitory effects and binding studies. The international journal of biochemistry & cell biology 20041001
Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells. American journal of respiratory cell and molecular biology 20041001
Functional characterization of a P2X receptor from Schistosoma mansoni. The Journal of biological chemistry 20041001
Role of macula densa adenosine triphosphate (ATP) in tubuloglomerular feedback. Kidney international 20041001
Suramin: potential in acute liver failure. Expert opinion on investigational drugs 20041001
Breast tissue characterization using FARMA modeling of ultrasonic RF echo. Ultrasound in medicine & biology 20041001
ATP-induced non-neuronal cell permeabilization in the rat inner retina. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929
The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. The Journal of biological chemistry 20040924
Adenosine 5'-triphosphate and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea pig prostate gland. European journal of pharmacology 20040924
Low-dose suramin enhanced paclitaxel activity in chemotherapy-naive and paclitaxel-pretreated human breast xenograft tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 20040915
Is there a role for chemotherapy in prostate cancer? British journal of cancer 20040913
Role of extracellular histidines in antagonist sensitivity of the rat P2X4 receptor. Neuroscience letters 20040902
Lysophospholipids and chemokines activate distinct signal transduction pathways in T helper 1 and T helper 2 cells. Cellular signalling 20040901
Activation of P2 nucleotide receptors stimulates acid efflux from astrocytes. Glia 20040901
Estrogen receptor-positive human epithelial ovarian carcinoma cells respond to the antitumor drug suramin with increased proliferation: possible insight into ER and epidermal growth factor signaling interactions in ovarian cancer. Gynecologic oncology 20040901
Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. The European journal of neuroscience 20040901
Sleeping sickness in brothers in london. The Pediatric infectious disease journal 20040901
Suramin sensitizing cells to ionizing radiation by inactivating DNA-dependent protein kinase. Radiation research 20040901
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses. The Journal of biological chemistry 20040820
Purinergic regulation of guinea pig suburothelial myofibroblasts. The Journal of physiology 20040815
Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology 20040801
Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor. Journal of lipid research 20040801
P2X receptor subtype-specific modulation of excitatory and inhibitory synaptic inputs in the rat brainstem. The Journal of physiology 20040801
The N-terminal Ca2+-independent calmodulin-binding site on the inositol 1,4,5-trisphosphate receptor is responsible for calmodulin inhibition, even though this inhibition requires Ca2+. Molecular pharmacology 20040801
Uridine 5'-triphosphate stimulates alveolar fluid clearance in the isolated rat lungs. Journal of pharmacological sciences 20040801
Development of a monoclonal antibody-based enzyme-linked immunoabsorbent assay for the binding of gp130 to the IL-6/IL-6R complex and its competitive inhibition. Journal of immunological methods 20040801
Induction of apoptosis in bone marrow cells is mediated via purinergic receptors. Bulletin of experimental biology and medicine 20040801
Oscillatory calcium responses mediated by P2Y2 purinergic receptors in terminal Schwann cells of longitudinal lanceolate endings isolated from rat vibrissae. The Journal of comparative neurology 20040726
Characterization of the ATP-hydrolysing activity of alpha-sarcoglycan. The Biochemical journal 20040701
The heparan sulfate-specific epitope 10E4 is NO-sensitive and partly inaccessible in glypican-1. Glycobiology 20040701
Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates. The Journal of physiology 20040701
Human complement factor I does not require cofactors for cleavage of synthetic substrates. Journal of immunology (Baltimore, Md. : 1950) 20040701
Comparison of noradrenaline and lysosphingolipid-induced vasoconstriction in mouse and rat small mesenteric arteries. Autonomic & autacoid pharmacology 20040701
Purinergic receptors coupled to intracellular Ca2+ signals and exocytosis in rat prostate neuroendocrine cells. The Journal of biological chemistry 20040625
Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation. Traffic (Copenhagen, Denmark) 20040601
Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice. Nature medicine 20040601
Biochemical characterization and crystallization of recombinant 3-phosphoglycerate kinase of Plasmodium falciparum. Biochimica et biophysica acta 20040601
Cheating death in the liver. Nature medicine 20040601
Effects of 20-hydroxyecdysone and other hormones on egg development, and identification of a vitellin-binding protein in the ovary of the tick, Amblyomma hebraeum. Journal of insect physiology 20040601
Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana. Annals of tropical medicine and parasitology 20040601
Expression of P2Y2 purinoceptors in MCG 101 murine sarcoma cells, and HT-29 human colon carcinoma cells. Autonomic neuroscience : basic & clinical 20040531
Cadmium inhibits GABA-activated ion currents by increasing intracellular calcium level in snail neurons. Brain research 20040522
Functional genomics of UV radiation responses in human cells. Mutation research 20040518
Soluble NTPDase: An additional system of nucleotide hydrolysis in rat blood serum. Life sciences 20040514
Extracellular ATP facilitates flow-induced vasodilatation in rat small mesenteric arteries. American journal of physiology. Heart and circulatory physiology 20040501
P2Y purinergic receptor regulation of CFTR chloride channels in mouse cardiac myocytes. The Journal of physiology 20040501
A Mg-dependent ecto-ATPase is increased in the infective stages of Trypanosoma cruzi. Parasitology research 20040501
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. Glia 20040501
Resistance to drug by different isolates Trypanosoma evansi in China. Acta tropica 20040501
Functional regulation of the cardiac ryanodine receptor by suramin and calmodulin involves multiple binding sites. Molecular pharmacology 20040501
UTP and diadenosine tetraphosphate accelerate wound healing in the rabbit cornea. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 20040501
Reactive blue 2 inhibition of cyclic AMP-dependent differentiation of rat C6 glioma cells by purinergic receptor-independent inactivation of phosphatidylinositol 3-kinase. Biochemical pharmacology 20040415
Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases. The Journal of biological chemistry 20040409
Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. The Journal of biological chemistry 20040409
Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage. The Journal of biological chemistry 20040402
P2X7 receptors stimulate AKT phosphorylation in astrocytes. British journal of pharmacology 20040401
Functional regulation of P2X6 receptors by N-linked glycosylation: identification of a novel alpha beta-methylene ATP-sensitive phenotype. Molecular pharmacology 20040401
Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist. European journal of medicinal chemistry 20040401
Synthesis and antitubulin activity of N1- and N4-substituted 3,5-dinitro sulfanilamides against African trypanosomes and Leishmania. Journal of medicinal chemistry 20040325
Lipid transfer particle mediates the delivery of diacylglycerol from lipophorin to fat body in larval Manduca sexta. Journal of lipid research 20040301
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle. The Journal of pharmacology and experimental therapeutics 20040301
Synthesis of nitric oxide in postganglionic myenteric neurons during endotoxemia: implications for gastric motor function in rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301
Vascular smooth muscle cells (VSMC) proliferation of streptozotocin-diabetic animals induced by diadenosine polyphosphates. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040301
[3H]alpha,beta-methylene ATP binding to P2X purinoceptor is unaffected by volatile anaesthetics. European journal of anaesthesiology 20040301
Response to ATP is accompanied by a Ca2+ influx via P2X purinoceptors in the coronary arterioles of golden hamsters. Archives of histology and cytology 20040301
Desensitization masks nanomolar potency of ATP for the P2X1 receptor. The Journal of biological chemistry 20040220
Stimulation of extracellular signal-regulated kinase pathway by suramin with concomitant activation of DNA synthesis in cultured cells. The Journal of pharmacology and experimental therapeutics 20040201
Adenosine tetraphosphate, Ap4, a physiological regulator of intraocular pressure in normotensive rabbit eyes. The Journal of pharmacology and experimental therapeutics 20040201
New 4-aminobicyclo[2.2.2]octane derivatives and their activities against Plasmodium falciparum and Trypanosoma b. rhodesiense. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201
Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection. The journal of pain : official journal of the American Pain Society 20040201
Inhibitory activities of sulfated proteoglycans on chondroitin sulfate A-mediated cytoadherence of Plasmodium falciparum isolates from Thailand. The American journal of tropical medicine and hygiene 20040201
A simple quantitative method for evaluation of angiogenesis activity. Assay and drug development technologies 20040201
Exploitation of heparanase inhibitors from microbial metabolites using an efficient visual screening system. The Journal of antibiotics 20040201
Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon. The Journal of comparative neurology 20040126
Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study. British journal of cancer 20040126
Randomized Phase II trial assessing estramustine and vinblastine combination chemotherapy vs estramustine alone in patients with progressive hormone-escaped metastatic prostate cancer. British journal of cancer 20040112
Nucleotide-mediated inhibition of alveolar fluid clearance in BALB/c mice after respiratory syncytial virus infection. American journal of physiology. Lung cellular and molecular physiology 20040101
Discrete but simultaneous release of adenine nucleotides and serotonin from mouse megakaryocytes as detected with patch- and carbon-fiber electrodes. American journal of physiology. Cell physiology 20040101
Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type. British journal of pharmacology 20040101
ATP-induced ATP release from astrocytes. Journal of neurochemistry 20040101
A Phase II trial of suramin monthly x 3 for hormone-refractory prostate carcinoma. Cancer 20040101
Diffusion of single cardiac ryanodine receptors in lipid bilayers is decreased by annexin 12. Biophysical journal 20040101
Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain 20040101
Megazol combined with suramin improves a new diagnosis index of the early meningo-encephalitic phase of experimental African trypanosomiasis. Tropical medicine & international health : TM & IH 20040101
Suramin and radiotherapy in newly diagnosed glioblastoma: phase 2 NABTT CNS Consortium study. Neuro-oncology 20040101
[Effect of suramin on proliferation and migration of lens epithelial cells in vitro]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20040101
Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo. International immunopharmacology 20040101
Extracellular ATP activates chloride and taurine conductances in cultured hippocampal neurons. Neurochemical research 20040101
Diquafosol elicits increases in net Cl- transport through P2Y2 receptor stimulation in rabbit conjunctiva. Ophthalmic research 20040101
Oxidative burst in suspension culture of Taxus cuspidata induced by a laminar shear stress in short-term. Biotechnology progress 20040101
Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Current topics in medicinal chemistry 20040101
Expression of functional purinergic receptors in pulmonary neuroepithelial bodies and their role in hypoxia chemotransmission. Biological chemistry 20040101
RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate. Experimental parasitology 20040101
Biopolymer-mediated suramin chemotherapy in the treatment of experimental brain tumours. Acta oncologica (Stockholm, Sweden) 20040101
Quality of life and emotional distress in advanced prostate cancer survivors undergoing chemotherapy. Health and quality of life outcomes 20040101
ATP in the mechanotransduction pathway of normal human chondrocytes. Biorheology 20040101
[Molecular mechanisms of regulatory action of adrenergic receptor agonists on functional activity of adenylyl cyclase signaling system of the ciliates Dileptus anser and Tetrahymena pyriformis]. Tsitologiia 20040101
P2X7-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms. Neuroscience 20040101
Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells. Neuroscience 20040101
[Regulation of the adenylate cyclase signaling system in cultured Dileptus anser and Tetrahymena pyriformis by insulin peptide superfamily]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20040101
Peritonitis-induced antitumor activity of peritoneal macrophages from uremic patients. Folia histochemica et cytobiologica 20040101
Dissecting individual current components of co-expressed human P2X1 and P2X7 receptors. Current topics in medicinal chemistry 20040101
Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. The Journal of clinical investigation 20031215
Exacerbation of TGF-beta-induced cataract by FGF-2 in cultured rat lenses. Molecular vision 20031215
Reduced expression of P2Y1 receptors in connexin43-null mice alters calcium signaling and migration of neural progenitor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20031210
Mechanisms of secretion of ATP from cortical astrocytes triggered by uridine triphosphate. Neuroreport 20031202
Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain. The Journal of pharmacology and experimental therapeutics 20031201
Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ions. British journal of pharmacology 20031201
Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide. Antioxidants & redox signaling 20031201
ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: dominance of P2Y2 receptors. British journal of pharmacology 20031201
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Developmental biology 20031201
Suramin inhibits the growth of malignant mesothelioma in vitro, and in vivo, in murine flank and intraperitoneal models. Lung cancer (Amsterdam, Netherlands) 20031201
Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. The British journal of dermatology 20031201
[Progress in researches on drugs for prostate cancer]. Zhonghua nan ke xue = National journal of andrology 20031201
The HIV-1 Tat transactivator protein: a therapeutic target? IUBMB life 20031201
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum. The Journal of biological chemistry 20031128
A novel form of cellular communication among thymic epithelial cells: intercellular calcium wave propagation. American journal of physiology. Cell physiology 20031101
ATP modulates intracellular Ca2+ and firing rate through a P2Y1 purinoceptor in cane toad pacemaker cells. The Journal of physiology 20031101
Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved. British journal of pharmacology 20031101
Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum. Gastroenterology 20031101
P2X receptor-mediated excitatory synaptic currents in somatosensory cortex. Molecular and cellular neurosciences 20031101
ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro. Brain research 20031024
Hydrogen ion dynamics and the Na+/H+ exchanger in cancer angiogenesis and antiangiogenesis. British journal of cancer 20031020
Aminophospholipids have no access to the luminal side of the biliary canaliculus: implications for thr specific lipid composition of the bile fluid. The Journal of biological chemistry 20031017
ATP causes glomus cell [Ca2+]c increase without corresponding increases in CSN activity. Respiratory physiology & neurobiology 20031016
High density lipoprotein-associated lysosphingolipids reduce E-selectin expression in human endothelial cells. Biochemical and biophysical research communications 20031010
Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells. Journal of lipid research 20031001
Purinergic signalling in the medullary mechanisms of respiratory control in the rat: respiratory neurones express the P2X2 receptor subunit. The Journal of physiology 20031001
P2X4, P2Y1 and P2Y2 receptors on rat alveolar macrophages. British journal of pharmacology 20031001
P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells. Journal of neurochemistry 20031001
P2X7 receptors in rat brain: presence in synaptic terminals and granule cells. Neurochemical research 20031001
Ecto-ATPase activity on the surface of Trypanosoma cruzi and its possible role in the parasite-host cell interaction. Parasitology research 20031001
Magnesium-dependent ecto-ATP diphosphohydrolase activity in Herpetomonas muscarum muscarum. Current microbiology 20031001
Effect of experimental diabetes on cholinergic, purinergic and peptidergic motor responses of the isolated rat bladder to electrical field stimulation or capsaicin. European journal of pharmacology 20030930
Antagonism of myotoxic and paralyzing activities of bothropstoxin-I by suramin. Toxicon : official journal of the International Society on Toxinology 20030915
ATP augments peptide release from rat sensory neurons in culture through activation of P2Y receptors. The Journal of pharmacology and experimental therapeutics 20030901
Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors. Glia 20030901
Early glial cell reactivity in experimental retinal detachment: effect of suramin. Investigative ophthalmology & visual science 20030901
Guillain-Barré syndrome after simultaneous therapy with suramin and interferon-alpha. European journal of neurology 20030901
Purinergic and adrenergic cotransmission in canine isolated and perfused gastroepiploic arteries. Clinical and experimental pharmacology & physiology 20030901
Wax moth, Galleria mellonella fat body receptor for high-density lipophorin (HDLp). Archives of insect biochemistry and physiology 20030901
Distinct receptors and different transduction mechanisms for ATP and adenosine at the frog motor nerve endings. The European journal of neuroscience 20030901
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. Journal of neuro-oncology 20030901
Polydeoxyribonucleotide (PDRN) promotes human osteoblast proliferation: a new proposal for bone tissue repair. Life sciences 20030829
Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030827
Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts. The Journal of biological chemistry 20030815
Phase I study of low-dose suramin as a chemosensitizer in patients with advanced non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20030815
Antifibrotic effects of suramin in injured skeletal muscle after laceration. Journal of applied physiology (Bethesda, Md. : 1985) 20030801
ATP-evoked increase in intracellular calcium via the P2Y receptor in proliferating bovine trophoblast cells. Cell and tissue research 20030801
Catalytic topoisomerase II inhibitors in cancer therapy. Pharmacology & therapeutics 20030801
p38 mitogen-activated protein kinase activation by ultraviolet A radiation in human dermal fibroblasts. Photochemistry and photobiology 20030801
P2Y(2) receptor elicits PAS-positive glycoprotein secretion from rabbit conjunctival goblet cells in vivo. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030801
[Influence of suramin on the proliferation of prostatic carcinoma cells PC-3M]. Zhonghua nan ke xue = National journal of andrology 20030801
Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030730
Intercellular calcium waves mediate preferential cell growth toward the wound edge in polarized hepatic cells. Experimental cell research 20030715
Characterisation of an uridine-specific binding site in rat cerebrocortical homogenates. Neurochemistry international 20030701
Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+. American journal of physiology. Heart and circulatory physiology 20030701
Suramin suppresses growth, alkaline-phosphatase and telomerase activity of human osteosarcoma cells in vitro. The international journal of biochemistry & cell biology 20030701
Pharmacological characterization of the human P2Y13 receptor. Molecular pharmacology 20030701
Effects of intravenous and infravesical administration of suramin, terazosin and BMY 7378 on bladder instability in conscious rats with bladder outlet obstruction. BJU international 20030701
Effect of halothane on the guanosine 5' triphosphate binding activity of G-protein alphai subunits. Anesthesiology 20030701
Hemangioblastic characteristics of fetal bone marrow-derived Flk1(+)CD31(-)CD34(-) cells. Experimental hematology 20030701
Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate. The Journal of biological chemistry 20030613
Kinetics of inhibition of sperm beta-acrosin activity by suramin. FEBS letters 20030605
Third-generation beta-blockers stimulate nitric oxide release from endothelial cells through ATP efflux: a novel mechanism for antihypertensive action. Circulation 20030603
Effects of varying impulse number on cotransmitter contributions to sympathetic vasoconstriction in rat tail artery. American journal of physiology. Heart and circulatory physiology 20030601
Pharmacological and biophysical properties of the human P2X5 receptor. Molecular pharmacology 20030601
Caffeine-mediated presynaptic long-term potentiation in hippocampal CA1 pyramidal neurons. Journal of neurophysiology 20030601
Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. The Journal of investigative dermatology 20030601
Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system. British journal of pharmacology 20030601
Current chemotherapy of human African trypanosomiasis. Parasitology research 20030601
Renal haemodynamics and natriuretic responses to intravenous administration of diadenosine tetraphosphate (Ap4A) and nicotinamide adenine dinucleotide (NAD) in rat. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030601
NF449, a novel picomolar potency antagonist at human P2X1 receptors. European journal of pharmacology 20030530
S1P3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate. European journal of pharmacology 20030523
Suramin inhibits beta-bungarotoxin-induced activation of N-methyl-D-aspartate receptors and cytotoxicity in primary neurons. Toxicology and applied pharmacology 20030515
P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197. European journal of pharmacology 20030502
A chicken model to study the embryology of cloacal exstrophy. Journal of pediatric surgery 20030501
Nitrergic prejunctional inhibition of purinergic neuromuscular transmission in the hamster proximal colon. Journal of neurophysiology 20030501
Fast Ca2+-induced potentiation of heat-activated ionic currents requires cAMP/PKA signaling and functional AKAP anchoring. Journal of neurophysiology 20030501
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. Parasitology research 20030501
Functional barrier principle for growth-factor-based articular cartilage repair. Osteoarthritis and cartilage 20030501
P2Y receptor regulation of cultured rat cerebral cortical cells: calcium responses and mRNA expression in neurons and glia. British journal of pharmacology 20030501
Pharmacological characterization of P2Y receptor subtypes on isolated tiger salamander Müller cells. Glia 20030415
Kinase inhibitors: not just for kinases anymore. Journal of medicinal chemistry 20030410
ATP modulation of sodium currents in rat dorsal root ganglion neurons. Brain research 20030404
P2 purinoceptors regulate calcium-activated chloride and fluid transport in 31EG4 mammary epithelia. American journal of physiology. Cell physiology 20030401
Mechanical stretch-induced apoptosis in smooth muscle cells is mediated by beta1-integrin signaling pathways. Hypertension (Dallas, Tex. : 1979) 20030401
Lipophorin interaction with the midgut of Rhodnius prolixus: characterization and changes in binding capacity. Insect biochemistry and molecular biology 20030401
Interaction of the D2short dopamine receptor with G proteins: analysis of receptor/G protein selectivity. Biochemical pharmacology 20030401
Treatment perspectives for human African trypanosomiasis. Fundamental & clinical pharmacology 20030401
Suppression by gabapentin of pain-related mechano-responses in mice given orthotopic tumor inoculation. Biological & pharmaceutical bulletin 20030401
ATP released from astrocytes during swelling activates chloride channels. Journal of neurophysiology 20030401
Adenosine 5'-triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland. British journal of pharmacology 20030401
Extracellular ATP-induced calcium channel inhibition mediated by P1/P2Y purinoceptors in hamster submandibular ganglion neurons. British journal of pharmacology 20030401
A model for left juxtaposition of the atrial appendages in the chick. Cardiology in the young 20030401
Characterization of an ectonucleoside triphosphate diphosphohydrolase 1 activity in alkaline phosphatase-depleted rat osseous plate membranes: possible functional involvement in the calcification process. Biochimica et biophysica acta 20030321
Inhibition of heparanase activity and heparanase-induced angiogenesis by suramin analogues. International journal of cancer 20030320
ATP-induced, sustained calcium signalling in cultured rat cortical astrocytes: evidence for a non-capacitative, P2X7-like-mediated calcium entry. FEBS letters 20030313
ATP-induced calcium oscillations and change of P2Y subtypes with culture conditions in HeLa cells. Cell biochemistry and function 20030301
Regulation of the calcium release channel from skeletal muscle by suramin and the disulfonated stilbene derivatives DIDS, DBDS, and DNDS. Biophysical journal 20030301
A novel early chorioallantoic membrane assay demonstrates quantitative and qualitative changes caused by antiangiogenic substances. The Journal of laboratory and clinical medicine 20030301
Expression and function of P2X purinoceptors in rat histaminergic neurons. British journal of pharmacology 20030301
Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation. Naunyn-Schmiedeberg's archives of pharmacology 20030301
HIV-1 integrase inhibitory substances from Coleus parvifolius. Phytotherapy research : PTR 20030301
Investigation of postjunctional alpha1- and alpha2-adrenoceptor subtypes in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice. British journal of pharmacology 20030301
Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways. Oncogene 20030227
IGF-1 receptor mediates differentiation of primary cultures of mouse skeletal myoblasts. Molecular and cellular endocrinology 20030227
Activation of deoxycytidine kinase by UV-C-irradiation in chronic lymphocytic leukemia B-lymphocytes. Biochemical pharmacology 20030215
P2Y-receptor regulates size of endothelial cells in an intracellular Ca2+ dependent manner. Life sciences 20030214
Nitric oxide inhibits adenosine 5'-triphosphate-induced Ca2+ response in inner hair cells of the guinea pig cochlea. Neuroscience letters 20030213
Multiple signalling pathways mediate fungal elicitor-induced beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. Journal of experimental botany 20030201
Blockade of sulfur mustard cytotoxicity in human epidermal keratinocytes with the purinergic receptor antagonist suramin. Veterinary and human toxicology 20030201
Teratogenic effects of suramin on the chick embryo. Anatomy and embryology 20030201
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of medicinal chemistry 20030130
Neurotransmitters involved in the fast inhibitory junction potentials in mouse distal colon. European journal of pharmacology 20030124
Cloning, tissue distribution and functional characterization of the chicken P2X1 receptor. FEBS letters 20030102
Mechanosensitivity and intercellular communication in HOBIT osteoblastic cells: a possible role for gap junction hemichannels. Biorheology 20030101
Cell swelling increases intracellular calcium in Necturus erythrocytes. Journal of cell science 20030101
A phase I study of intravesical suramin for the treatment of superficial transitional cell carcinoma of the bladder. The Journal of urology 20030101
Presence of diadenosine polyphosphates in the aqueous humor: their effect on intraocular pressure. The Journal of pharmacology and experimental therapeutics 20030101
Characterization of the 5-hydroxytryptamine receptors mediating contraction in the pig isolated intravesical ureter. British journal of pharmacology 20030101
Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26. Cell calcium 20030101
Role of chemotherapy in hormone-refractory prostate cancer. Old issues, recent advances and new perspectives. Urologia internationalis 20030101
Modulation of myocardial contractility by lysophosphatidic acid (LPA). Journal of molecular and cellular cardiology 20030101
Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells. BMC cancer 20030101
CD45 protein-tyrosine phosphatase inhibitor development. Current topics in medicinal chemistry 20030101
Suramin modulates wound healing of rabbit conjunctiva after trabeculectomy: comparison with mitomycin C. Current eye research 20030101
Suramin selectively inhibits carcinoma cell growth that is dependent on extracellular polyamines. Anticancer research 20030101
Alzheimer's amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytes. Neuromolecular medicine 20030101
Up-regulation of P2X2, P2X4 receptor and ischemic cell death: prevention by P2 antagonists. Neuroscience 20030101
Purinoceptor-mediated contractility of the perfused uterine vasculature of the guinea-pig: influence of oestradiol and pregnancy. Clinical and experimental pharmacology & physiology 20030101
[Comparative effects of complement inhibitors in vitro and in vivo experiments: an immunoenzyme method in studying subcomponent C1q inhibition and complement inhibition in model animals]. Biomeditsinskaia khimiia 20030101
Effects of extracellular atp on axonal transport in cultured mouse dorsal root ganglion neurons. Neuroscience 20030101
Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slices. Neuroscience 20030101
Effects of sphingosine 1-phosphate on excitation-contraction coupling in mammalian skeletal muscle. Journal of muscle research and cell motility 20030101
Suramin inhibits the in vitro expression of encephalitis B virus proteins NS3 and E. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101
[The return of sleeping sickness in an epidemic form: international action for drugs]. Nederlands tijdschrift voor geneeskunde 20021228
Suramin interacts with the calmodulin binding site on the ryanodine receptor, RYR1. The Journal of biological chemistry 20021220
Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway. Virology 20021220
Calcium rise in cultured neurons from medial septum elicits calcium waves in surrounding glial cells. Brain research 20021213
Interactions between the juxtamembrane domain of the EGFR and calmodulin measured by surface plasmon resonance. Cellular signalling 20021201
Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen. Parasitology international 20021201
Suramin reduces infarct volume in a model of focal brain ischemia in rats. Experimental brain research 20021201
Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6). The Journal of physiology 20021201
Role of G protein and protein kinase signalling in influenza virus budding in MDCK cells. The Journal of general virology 20021201
Possible involvement of extracellular signal-regulated kinases 1/2 in mitogenic response of periodontal ligament cells to enamel matrix derivative. European journal of oral sciences 20021201
P2 receptors in the murine gastrointestinal tract. Neuropharmacology 20021201
Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor. The Journal of biological chemistry 20021122
Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. The Journal of biological chemistry 20021115
Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects. British journal of cancer 20021104
Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors. Cellular signalling 20021101
Regional variation in P2 receptor expression in the rat pulmonary arterial circulation. British journal of pharmacology 20021101
Changes in electrophysiological properties in the prostatic portion of vas deferens from spontaneously hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology 20021101
P2Y-receptors mediating an inhibition of the evoked entry of calcium through N-type calcium channels at neuronal processes. The Journal of pharmacology and experimental therapeutics 20021101
Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist. Molecular pharmacology 20021101
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor. Neuropharmacology 20021101
P2X purinergic receptor antagonist accelerates skin barrier repair and prevents epidermal hyperplasia induced by skin barrier disruption. The Journal of investigative dermatology 20021101
Multiple P2 receptors contribute to a transient increase in intracellular Ca2+ concentration in ATP-stimulated rat brown adipocytes. Experimental physiology 20021101
Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells. European journal of clinical pharmacology 20021101
Neoplastic change in Onchocerca volvulus and its relation to ivermectin treatment. Parasitology 20021101
Characterization of lipophorin binding to the fat body of Rhodnius prolixus. Insect biochemistry and molecular biology 20021101
Substrate specificity and inhibitor studies of a membrane-bound ganglioside sialidase isolated from human brain tissue. Biological chemistry 20021101
Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists. Biochemical pharmacology 20021015
Application of kinetic-based biospecific affinity chromatographic systems to ATP-dependent enzymes: studies with yeast hexokinase. Analytical biochemistry 20021015
Adenosine triphosphate accelerates recovery from hypoxic/hypoglycemic perturbation of guinea pig hippocampal neurotransmission via a P(2) receptor. Brain research 20021011
Ectonucleotide diphosphohydrolase activity in Crithidia deanei. Parasitology research 20021001
Regulation of the avidity of ternary complexes containing the human 5-HT(1A) receptor by mutation of a receptor contact site on the interacting G protein alpha subunit. British journal of pharmacology 20021001
Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1). Molecular pharmacology 20021001
Nomogram for overall survival of patients with progressive metastatic prostate cancer after castration. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021001
Recent advances in drug-induced neuropathies. Current opinion in neurology 20021001
ATP-induced endothelium-independent enhancement of lymphatic vasomotion in guinea-pig mesentery involves P2X and P2Y receptors. British journal of pharmacology 20021001
Purines and pyrimidines are not involved in NANC relaxant responses in the rabbit vaginal wall. British journal of pharmacology 20021001
IL-1 beta potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Essential role of growth factor receptor-mediated signal transduction through the mitogen-activated protein kinase pathway in early embryogenesis of the echinoderm. Development, growth & differentiation 20021001
No evidence for inhibition of ENaC through CFTR-mediated release of ATP. Biochimica et biophysica acta 20020920
Evoked and spontaneous purinergic junctional Ca2+ transients (jCaTs) in rat small arteries. Circulation research 20020920
Sensory afferent selective role of P2 receptors in the nucleus tractus solitarii for mediating the cardiac component of the peripheral chemoreceptor reflex in rats. The Journal of physiology 20020915
Purine and pyrimidine (P2) receptors as drug targets. Journal of medicinal chemistry 20020912
Preliminary structure-antiangiogenic activity relationships of 4-senecioyloxymethyl-6,7-dimethoxycoumarin. Bioorganic & medicinal chemistry letters 20020902
Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct. American journal of physiology. Renal physiology 20020901
Cholinergic and nitrergic regulation of in vivo giant migrating contractions in rat colon. American journal of physiology. Gastrointestinal and liver physiology 20020901
Enzyme kinetics and pharmacological characterization of nucleotidases released from the guinea pig isolated vas deferens during nerve stimulation: evidence for a soluble ecto-nucleoside triphosphate diphosphohydrolase-like ATPase and a soluble ecto-5'-nucleotidase-like AMPase. The Journal of pharmacology and experimental therapeutics 20020901
Evidence that action potential generation is not the exclusive determinant to trigger spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle. Acta physiologica Scandinavica 20020901
Ionic currents activated via purinergic receptors in the cumulus cell-enclosed mouse oocyte. Biology of reproduction 20020901
Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901
Comparison of the effect of ATP on intracellular calcium ion dynamics between rat testicular and cerebral arteriole smooth muscle cells. Cell calcium 20020901
Characterization of cholera toxin B subunit-induced Ca(2+) influx in neuroblastoma cells: evidence for a voltage-independent GM1 ganglioside-associated Ca(2+) channel. Journal of neuroscience research 20020901
Characterization of cholesterol transport from midgut to fat body in Manduca sexta larvae. Insect biochemistry and molecular biology 20020901
Sesquiterpenes and alkaloids from Lindera chunii and their inhibitory activities against HIV-1 integrase. Chemical & pharmaceutical bulletin 20020901
ATP-induced internalization of amphibian epithelial P2X receptors is linked to channel opening. Pflugers Archiv : European journal of physiology 20020901
Mast cell-derived VEGF enhances the passage of IgE FE-3 through the rat aortic endothelial cell monolayer. International archives of allergy and immunology 20020901
Establishment of the organizing activity of the lower endodermal half of the dorsal marginal zone is a primary and necessary event for dorsal axis formation in Cynops pyrrhogaster. The International journal of developmental biology 20020901
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors. The European journal of neuroscience 20020901
Calcium signaling in and between brain astrocytes and endothelial cells. Acta neurologica Belgica 20020901
The DC electrical-field-induced Ca(2+) response and growth stimulation of multicellular tumor spheroids are mediated by ATP release and purinergic receptor stimulation. Journal of cell science 20020815
Randomized study of three different doses of suramin administered with a fixed dosing schedule in patients with advanced prostate cancer: results of intergroup 0159, cancer and leukemia group B 9480. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020815
Cellular mechanisms for apical ATP effects on intracellular pH in human bronchial epithelium. The Journal of physiology 20020815
Ultraviolet-B activates components of the systemin signaling pathway in Lycopersicon peruvianum suspension-cultured cells. The Journal of biological chemistry 20020809
GLUT4-containing vesicles are released from membranes by phospholipase D cleavage of a GPI anchor. American journal of physiology. Endocrinology and metabolism 20020801
In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cell migration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton. International journal of oncology 20020801
Role of luminal ATP in regulating electrogenic Na(+) absorption in guinea pig distal colon. American journal of physiology. Gastrointestinal and liver physiology 20020801
Uridine nucleotide-induced stimulation of gluconeogenesis in isolated rat proximal tubules. Naunyn-Schmiedeberg's archives of pharmacology 20020801
ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes. Journal of neuroimmunology 20020801
Blastopore formation and dorsal mesoderm induction are independent events in early Cynops embryogenesis. Development, growth & differentiation 20020801
Activation of phospholipase D-2 by P2X(7) agonists in rat submandibular gland acini. Journal of lipid research 20020801
Cloning and characterization of two novel zebrafish P2X receptor subunits. Biochemical and biophysical research communications 20020726
Targeting the cell cycle for cancer therapy. British journal of cancer 20020715
Anticytokine treatment prevents the increase in the activity of ATP-ubiquitin- and Ca(2+)-dependent proteolytic systems in the muscle of tumour-bearing rats. Cytokine 20020707
Identification of active antiviral compounds against a New York isolate of West Nile virus. Antiviral research 20020701
Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei. Molecular and biochemical parasitology 20020701
A phase I study of suramin with once- or twice-monthly dosing in patients with advanced cancer. Cancer chemotherapy and pharmacology 20020701
Suramin-induced reversal of chronic cerebral vasospasm in experimental subarachnoid hemorrhage. Journal of neurosurgery 20020701
Pharmacological characterization of a UTP-sensitive P2Y nucleotide receptor in organ cultured coronary arteries. Vascular pharmacology 20020701
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-2002. A 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to Africa. The New England journal of medicine 20020627
ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Coordinate release of ATP and GABA at in vitro synapses of lateral hypothalamic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets. Molecular and cellular endocrinology 20020614
High activity Rhenium-186 HEDP with autologous peripheral blood stem cell rescue: a phase I study in progressive hormone refractory prostate cancer metastatic to bone. British journal of cancer 20020605
Sphingosine 1-phosphate induces Ca2+ transients and cytoskeletal rearrangement in C2C12 myoblastic cells. American journal of physiology. Cell physiology 20020601
P2X purinergic receptor channel expression and function in bovine aortic endothelium. American journal of physiology. Heart and circulatory physiology 20020601
Cluster of African trypanosomiasis in travelers to Tanzanian national parks. Emerging infectious diseases 20020601
ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater. Pain 20020601
Effect of suramin on myotoxicity of some crotalid snake venoms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020601
Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cells. British journal of pharmacology 20020601
Functional screening of G protein-coupled receptors by measuring intracellular calcium with a fluorescence microplate reader. Journal of biomolecular screening 20020601
Effect of purinergic agonists and antagonists on insulin secretion from INS-1 cells (insulinoma cell line) and rat pancreatic islets. Canadian journal of physiology and pharmacology 20020601
[Effect of activation and blockade of central P2X receptors on body temperature]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020601
Adenosine 5'-triphosphate-evoked calcium responses in terminal Schwann cells of lanceolate sensory endings isolated from rat vibrissae. Neuroscience letters 20020517
Mg(2+)-sensitive non-capacitative basolateral Ca(2+) entry secondary to cell swelling in the polarized renal A6 epithelium. The Journal of physiology 20020515
ATP stimulates glucose transport through activation of P2 purinergic receptors in C(2)C(12) skeletal muscle cells. Archives of biochemistry and biophysics 20020515
Activation of ATP receptor increases the cytosolic Ca(2+) concentration in ventral tegmental area neurons of rat brain. Brain research 20020510
Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ('Iressa'). British journal of cancer 20020506
Nonselective cation conductance activated by muscarinic and purinergic receptors in rat spiral ganglion neurons. American journal of physiology. Cell physiology 20020501
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart. American journal of physiology. Heart and circulatory physiology 20020501
Enhanced IPC by activation of pertussis toxin-sensitive and -insensitive G protein-coupled purinoceptors. American journal of physiology. Heart and circulatory physiology 20020501
Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro. Journal of applied physiology (Bethesda, Md. : 1985) 20020501
Purinergic receptor signaling at the basolateral membrane of macula densa cells. Journal of the American Society of Nephrology : JASN 20020501
Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C. Journal of neurochemistry 20020501
Suramin's development: what did we learn? Investigational new drugs 20020501
Carvedilol inhibits pressure-induced increase in oxidative stress in coronary smooth muscle cells. Hypertension research : official journal of the Japanese Society of Hypertension 20020501
Inhibition of prostate carcinoma establishment and metastatic growth in mice by an antiangiogenin monoclonal antibody. International journal of cancer 20020420
Extracellular mRNA induces dendritic cell activation by stimulating tumor necrosis factor-alpha secretion and signaling through a nucleotide receptor. The Journal of biological chemistry 20020412
Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity. British journal of cancer 20020408
Nucleotide receptors involved in UTP-induced rat arterial smooth muscle cell migration. Circulation research 20020405
Receptor mediated yolk protein uptake in the crab Scylla serrata: crustacean vitellogenin receptor recognizes related mammalian serum lipoproteins. Molecular reproduction and development 20020401
Regional specification of the head and trunk-tail organizers of a urodele (Cynops pyrrhogaster) embryo is patterned during gastrulation. Developmental biology 20020401
Suppression of myocardial inflammation using suramin, a growth factor blocker. Circulation journal : official journal of the Japanese Circulation Society 20020401
Generalized loss of inhibitory innervation reverses serotonergic inhibition into excitation in a rabbit model of TNBS-colitis. British journal of pharmacology 20020401
Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats. British journal of pharmacology 20020401
Characteristics of ATP-induced current through P2X7 receptor in NG108-15 cells: unique antagonist sensitivity and lack of pore formation. Japanese journal of pharmacology 20020401
Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase. The Journal of biological chemistry 20020322
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P2Y2 purinoceptors in human umbilical vein endothelial cells. Circulation research 20020322
Multiple regulation by external ATP of nifedipine-insensitive, high voltage-activated Ca(2+) current in guinea-pig mesenteric terminal arteriole. The Journal of physiology 20020315
P2Y11 receptors activate adenylyl cyclase and contribute to nucleotide-promoted cAMP formation in MDCK-D(1) cells. A mechanism for nucleotide-mediated autocrine-paracrine regulation. The Journal of biological chemistry 20020308
Adenosine 5'-triphosphate inhibits slow depolarization induced by repetitive dorsal root stimulation via P2Y purinoceptors in substantia gelatinosa neurons of the adult rat spinal cord slices with the dorsal root attached. Neuroscience letters 20020308
Sequence-dependent effects of ZD1839 ('Iressa') in combination with cytotoxic treatment in human head and neck cancer. British journal of cancer 20020304
ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. American journal of physiology. Renal physiology 20020301
Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors. The Biochemical journal 20020301
Effects of extracellular ATP on freshly isolated mouse skeletal muscle cells during pre-natal and post-natal development. Pflugers Archiv : European journal of physiology 20020301
Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors. British journal of pharmacology 20020301
Capillary electrophoresis investigation of a partially unfolded conformation of beta(2)-microglobulin. Electrophoresis 20020301
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics. Pain 20020301
Screening of acyl hydrazide proteinase inhibitors for antiparasitic activity against Trypanosoma brucei. International journal of antimicrobial agents 20020301
Interaction between P2Y and NMDA receptors in layer V pyramidal neurons of the rat prefrontal cortex. Neuropharmacology 20020301
Capillary plexus development in the day five to day six chick chorioallantoic membrane is inhibited by cytochalasin D and suramin. The Journal of experimental zoology 20020215
Regulation of K(ATP) channels by P(2Y) purinoceptors coupled to PIP(2) metabolism in guinea pig ventricular cells. American journal of physiology. Heart and circulatory physiology 20020201
Suramin affects coupling of rhodopsin to transducin. Biophysical journal 20020201
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms. European journal of pharmacology 20020201
Inhibition of adenylyl cyclase by neuronal P2Y receptors. British journal of pharmacology 20020201
Pressure promotes angiotensin II--mediated migration of human coronary smooth muscle cells through increase in oxidative stress. Hypertension (Dallas, Tex. : 1979) 20020201
[African trypanosomiasis--a rare imported disease]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020110
Characterization of an ecto-ATPase of Tritrichomonas foetus. Veterinary parasitology 20020103
Interactions between zona pellucida glycoproteins and sperm proacrosin/acrosin during fertilization. Journal of reproductive immunology 20020101
Regulation of transcervical permeability by two distinct P2 purinergic receptor mechanisms. American journal of physiology. Cell physiology 20020101
African trypanosomiasis in travelers returning to the United Kingdom. Emerging infectious diseases 20020101
Development of Gs-selective inhibitory compounds. Methods in enzymology 20020101
Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro. European journal of biochemistry 20020101
Controversies in chemotherapy of prostate cancer. Frontiers of radiation therapy and oncology 20020101
Cholinergic and purinergic contribution to the micturition reflex in conscious rats with long-term bladder outlet obstruction. Neurourology and urodynamics 20020101
Chemotherapy of human African trypanosomiasis. Current pharmaceutical design 20020101
Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain. Naunyn-Schmiedeberg's archives of pharmacology 20020101
Chemotherapy-induced peripheral neuropathy. Journal of neurology 20020101
Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons. Neuroscience 20020101
Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis. BMC infectious diseases 20020101
Suramin affects capsaicin responses and capsaicin-noxious heat interactions in rat dorsal root ganglia neurones. Physiological research 20020101
Inhibition by female sex steroids of peristalsis in the guinea pig small intestine. Digestion 20020101
Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists. Current pharmaceutical design 20020101
Characterization of specific GTP binding sites in C2C12 mouse skeletal muscle cells. Journal of muscle research and cell motility 20020101
Regulation of leukotriene synthesis by arachidonic acid in human polymorphonuclear leukocyte adhesive interactions is dependent on the presence of albumin. Cell biology international 20020101
Human vascular endothelial cells with extended life spans: in vitro cell response, protein expression, and angiogenesis. Angiogenesis 20020101
New mouse model of vein bypass graft atherosclerosis. Heart, lung & circulation 20020101
Learning in the multiple class random neural network. IEEE transactions on neural networks 20020101
The low density lipoprotein receptor-related protein contributes to selective uptake of high density lipoprotein cholesteryl esters by SW872 liposarcoma cells and primary human adipocytes. The Journal of biological chemistry 20011228
Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria. Toxicology 20011201
Extracellular nucleotides regulate cellular functions of podocytes in culture. American journal of physiology. Renal physiology 20011201
Roles of norepinephrine and ATP in sympathetically evoked vasoconstriction in rat tail and hindlimb in vivo. American journal of physiology. Heart and circulatory physiology 20011201
P2X2 receptor mediates stimulation of parasensory cation absorption by cochlear outer sulcus cells and vestibular transitional cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201
ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells. Archives of pharmacal research 20011201
FGF signaling is essential for the early events in the development of the chick nervous system and mesoderm. The International journal of developmental biology 20011201
ATP and nitric oxide modulate intracellular calcium in isolated pillar cells of the guinea pig cochlea. Journal of the Association for Research in Otolaryngology : JARO 20011201
Vasoactive intestinal peptide is involved in the inhibitory effect of interleukin-1 beta on the jejunal contractile response induced by acetylcholine. Gastroenterologie clinique et biologique 20011201
Chloride dependent intracellular pH effects of external ATP in cultured human non-pigmented ciliary body epithelium. Current eye research 20011201
Voltage-independent inhibition of P/Q-type Ca2+ channels in adrenal chromaffin cells via a neuronal Ca2+ sensor-1-dependent pathway involves Src family tyrosine kinase. The Journal of biological chemistry 20011130
Suramin-induced neuropathy in an animal model. Journal of the neurological sciences 20011115
Nontoxic doses of suramin enhance activity of doxorubicin in prostate tumors. The Journal of pharmacology and experimental therapeutics 20011101
Activation of p90RSK and growth stimulation of multicellular tumor spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101
Availability and affordability of treatment for Human African Trypanosomiasis. Tropical medicine & international health : TM & IH 20011101
Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle. Acta physiologica Scandinavica 20011101
Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization. Journal of cell science 20011101
Fixed higher dose schedule of suramin plus hydrocortisone in patients with hormone refractory prostate carcinoma a multicenter Phase II study. Cancer 20011101
Synthesis and biological evaluation of novel bisindolylmaleimides that inhibit vascular endothelial cell proliferation. Bioorganic & medicinal chemistry letters 20011022
Development of purinergic sensitivity in sensory neurons after peripheral nerve injury in the rat. Brain research 20011012
Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. American journal of physiology. Gastrointestinal and liver physiology 20011001
In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense. Planta medica 20011001
P2X and P2Y purinoreceptors mediate ATP-evoked calcium signalling in optic nerve glia in situ. Cell calcium 20011001
PC12 cells stimulate vascular smooth muscle growth. Journal of cardiovascular pharmacology 20011001
Hamao Umezawa Memorial Award Lecture: 'An Odyssey in the Viral Chemotherapy Field'. International journal of antimicrobial agents 20011001
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines. Journal of immunology (Baltimore, Md. : 1950) 20010915
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010915
Dehydroepiandrosterone sulfate (DHEAS) suppresses P2X purinoceptor-coupled responses in PC12 cells. Neurochemistry international 20010901
Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB. Journal of cellular physiology 20010901
Cloning and characterization of a functional P2X receptor from larval bullfrog skin. American journal of physiology. Cell physiology 20010901
ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Dynamic and stable pools of apoE differ functionally at the HepG2 cell surface. Journal of lipid research 20010901
NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors. Naunyn-Schmiedeberg's archives of pharmacology 20010901
Ca2+ signaling regulated by an ATP-dependent autocrine mechanism in astrocytes. Neuroreport 20010828
Novel purinergic sensitivity develops in injured sensory axons following sciatic nerve transection in rat. Brain research 20010824
Purinergic-independent calcium signaling mediates recovery from hepatocellular swelling: implications for volume regulation. The Journal of biological chemistry 20010817
Nontoxic doses of suramin enhance activity of paclitaxel against lung metastases. Cancer research 20010815
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease. The EMBO journal 20010801
Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity. The American journal of pathology 20010801
Dual mechanism of intercellular communication in HOBIT osteoblastic cells: a role for gap-junctional hemichannels. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010801
ATP induces Ca(2+) signaling in human chondrons cultured in three-dimensional agarose films. Osteoarthritis and cartilage 20010801
Extracellular ATP activates a P2 receptor in necturus erythrocytes during hypotonic swelling. The Journal of membrane biology 20010801
Treatment of hormone refractory prostate cancer. Seminars in urologic oncology 20010801
Effect of in vivo and in vitro ethanol on adrenergic and purinergic responses of the bisected rat vas deferens to low and high frequency pulses. Journal of autonomic pharmacology 20010801
Cdc25A phosphatase suppresses apoptosis induced by serum deprivation. Oncogene 20010727
HGF/SF induces mesothelial cell migration and proliferation by autocrine and paracrine pathways. Experimental cell research 20010715
Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium. American journal of physiology. Cell physiology 20010701
Neural regulation of in vitro giant contractions in the rat colon. American journal of physiology. Gastrointestinal and liver physiology 20010701
A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in adenosine acquisition and virulence. Archives of biochemistry and biophysics 20010701
Toxicity, efficacy, and pharmacology of suramin in adults with recurrent high-grade gliomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010701
Protein binding alters the activity of suramin, carboxyamidotriazole, and UCN-01 in an ex vivo rat aortic ring angiogenesis assay. Clinical cancer research : an official journal of the American Association for Cancer Research 20010701
Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clinical cancer research : an official journal of the American Association for Cancer Research 20010701
ATP modulates Na+ channel gating and induces a non-selective cation current in a neuronal hippocampal cell line. Brain research 20010622
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation. European journal of pharmacology 20010622
Probing the interaction of dengue virus envelope protein with heparin: assessment of glycosaminoglycan-derived inhibitors. Journal of medicinal chemistry 20010621
The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells. Journal of immunology (Baltimore, Md. : 1950) 20010615
Extracellular nucleotides differentially regulate interleukin-1beta signaling in primary human astrocytes: implications for inflammatory gene expression. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615
Prognostic significance of reverse transcriptase polymerase chain reaction for prostate-specific antigen in men with hormone-refractory prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010615
Synapse-glia interactions at the mammalian neuromuscular junction. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Endothelium-dependent relaxation induced by cathepsin G in porcine pulmonary arteries. British journal of pharmacology 20010601
Genomic structure, developmental distribution and functional properties of the chicken P2X(5) receptor. Journal of neurochemistry 20010601
Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20010601
ATP but not adenosine inhibits nonquantal acetylcholine release at the mouse neuromuscular junction. The European journal of neuroscience 20010601
Neural retina of chick embryo in organ culture: effects of blockade of growth factors by suramin. Cell and tissue research 20010601
Modulation of cyclooxygenase-2 and brain reactive astrogliosis by purinergic P2 receptors. Annals of the New York Academy of Sciences 20010601
Aldosterone upregulates purinergic responses in larval amphibian skin epithelium. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010601
Evidence against inhibition of sarcoplasmic reticulum Ca2+-pump as mechanism of H2O2-induced contraction of rat aorta. Acta pharmacologica Sinica 20010601
[Activation of p38 and c-Jun NH2-terminal kinase mitogen-activated protein kinases in human prostate carcinoma cell lines with different metastatic potentials]. Zhonghua bing li xue za zhi = Chinese journal of pathology 20010601
EGR-1, a UV-inducible gene in p53(-/-) mouse cells. Experimental cell research 20010515
Mechanisms of P2 receptor-evoked DNA synthesis in thyroid FRTL-5 cells. Journal of cellular physiology 20010501
ATP induces intracellular calcium increases and actin cytoskeleton disaggregation via P2x receptors. Cell calcium 20010501
Indomethacin and telomerase activity in tumor growth retardation. International journal of oncology 20010501
Suramin and the suramin analogue NF307 discriminate among calmodulin-binding sites. The Biochemical journal 20010501
Transporters in African trypanosomes: role in drug action and resistance. International journal for parasitology 20010501
Coronary vasomotor and cardiac electrophysiologic effects of diadenosine polyphosphates and nonhydrolyzable analogs in the guinea pig. Journal of cardiovascular pharmacology 20010501
Mechanical response to electrical field stimulation of rat, guinea-pig, monkey and human detrusor muscle: a comparative study. Naunyn-Schmiedeberg's archives of pharmacology 20010501
Effect on urinary bladder function and arterial blood pressure of the activation of putative purine receptors in brainstem areas. Autonomic neuroscience : basic & clinical 20010412
Adenosine triphosphate activates mitogen-activated protein kinase in human granulosa-luteal cells. Endocrinology 20010401
Propagation of intercellular calcium waves in retinal astrocytes and Müller cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010401
Purinergic regulation of intracellular Ca2+ concentration of rat pituitary folliculo-stellate cells in primary culture. Journal of neuroendocrinology 20010401
Direct autocrine inhibition and cAMP-dependent potentiation of single L-type Ca2+ channels in bovine chromaffin cells. The Journal of physiology 20010401
ATP and ADP hydrolysis in fish, chicken and rat synaptosomes. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010401
Possible involvement of ERK 1/2 in UVA-induced melanogenesis in cultured normal human epidermal melanocytes. Pigment cell research 20010401
Phase 1 drug interaction study of suramin and warfarin in patients with prostate cancer. American journal of clinical oncology 20010401
Treatment of patients with metastatic germ cell tumors relapsing after high-dose chemotherapy. World journal of urology 20010401
Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP). Journal of inorganic biochemistry 20010401
Effects of ATP on intracellular calcium dynamics of neurons and satellite cells in rat superior cervical ganglia. Histochemistry and cell biology 20010401
Nicorandil--induced ATP release in endothelial cells of rat caudal artery is associated with increase in intracellular Ca(2+). European journal of pharmacology 20010330
Molecular cloning and characterization of the mouse P2Y4 nucleotide receptor. European journal of pharmacology 20010330
Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010315
Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer research 20010315
Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study. Cancer research 20010315
Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists. Neurochemistry international 20010301
International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacological reviews 20010301
Short- and long-term functional alterations of the skeletal muscle calcium release channel (Ryanodine receptor) by Suramin: apparent dissociation of single channel current recording and [3H]ryanodine binding. Molecular pharmacology 20010301
Complexities of measuring antagonist potency at P2X(7) receptor orthologs. The Journal of pharmacology and experimental therapeutics 20010301
Coexpression of P2X(3) and P2X(2) receptor subunits in varying amounts generates heterogeneous populations of P2X receptors that evoke a spectrum of agonist responses comparable to that seen in sensory neurons. The Journal of pharmacology and experimental therapeutics 20010301
Serum prostate-specific antigen decline as a marker of clinical outcome in hormone-refractory prostate cancer patients: association with progression-free survival, pain end points, and survival. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010301
Ectoenzymatic breakdown of diadenosine polyphosphates by Xenopus laevis oocytes. European journal of biochemistry 20010301
Metabolic studies of glycosphingolipid accumulation in mucopolysaccharidosis IIID. Molecular genetics and metabolism 20010301
Nerve evoked P2X receptor contractions of rat mesenteric arteries; dependence on vessel size and lack of role of L-type calcium channels and calcium induced calcium release. British journal of pharmacology 20010301
Identification of P1 and P2 purinoceptors in the aorta of the lizard (Agama sp.). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010301
P2Y receptor-mediated inhibition of voltage-activated Ca(2+) currents in PC12 cells. The European journal of neuroscience 20010301
Pharmacological characterisation of pyrimidinoceptor responses in NG108-15 cells. European journal of pharmacology 20010301
Urokinase activity in corneal fibroblasts may be modulated by DNA damage and secreted proteins. Photochemistry and photobiology 20010301
Regulation of chicken gizzard ecto-ATPase activity by modulators that affect its oligomerization status. Archives of biochemistry and biophysics 20010301
Vascular smooth muscle cell proliferation is effectively suppressed by the non-specific growth factor inhibitor suramin. Japanese heart journal 20010301
General aspects of anti-angiogenesis and cancer therapy. Expert opinion on biological therapy 20010301
[Mechanism of the activation of extracellular signal-regulated kinase (ERK) in prostate cancer cell lines with different metastatic potential]. Zhonghua yi xue za zhi 20010225
G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways. The Journal of biological chemistry 20010216
N-unsubstituted glucosamine in heparan sulfate of recycling glypican-1 from suramin-treated and nitrite-deprived endothelial cells. mapping of nitric oxide/nitrite-susceptible glucosamine residues to clustered sites near the core protein. The Journal of biological chemistry 20010209
Suramin prevents cerebellar granule cell-death induced by dequalinium. Neurochemistry international 20010201
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole. American journal of physiology. Heart and circulatory physiology 20010201
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed. British journal of pharmacology 20010201
The effects of P2Y receptor agonists and adenosine on prostaglandin production by the guinea-pig uterus. British journal of pharmacology 20010201
Müller cell Ca2+ waves evoked by purinergic receptor agonists in slices of rat retina. Journal of neurophysiology 20010201
Differential localization of P2 receptor subtypes in mesenteric arteries and veins of normotensive and hypertensive rats. The Journal of pharmacology and experimental therapeutics 20010201
Intercellular communication upon mechanical stimulation of CPAE- endothelial cells is mediated by nucleotides. Cell calcium 20010201
Purinoceptor-mediated calcium mobilization and proliferation in HaCaT keratinocytes. Journal of dermatological science 20010201
Angiogenesis: regulators and clinical applications. Biochemical pharmacology 20010201
Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion. British journal of cancer 20010201
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
Peritubular fluid viscosity modulates H+ flux in proximal tubules through NO release. American journal of physiology. Renal physiology 20010201
The influence of mechlorethamine on the activity of ecto-ATPase of rat lymphocytes. Annales pharmaceutiques francaises 20010201
Current status of cytotoxic chemotherapy in hormone refractory prostate cancer. European urology 20010201
Alteration of spontaneous firing rate of primary myelinated afferents by ATP in adjuvant-induced inflamed rats. Brain research bulletin 20010115
Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery. European journal of pharmacology 20010105
Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s. Drug metabolism and disposition: the biological fate of chemicals 20010101
Astrocyte-endothelial cell calcium signals conveyed by two signalling pathways. The European journal of neuroscience 20010101
Uptake and mode of action of drugs used against sleeping sickness. Biochemical pharmacology 20010101
Potentiation of cytokine induction of group IIA phospholipase A(2) in rat mesangial cells by ATP and adenosine via the A2A adenosine receptor. British journal of pharmacology 20010101
Multiple P2X receptors on guinea-pig pelvic ganglion neurons exhibit novel pharmacological properties. British journal of pharmacology 20010101
Two subtypes of G protein-coupled nucleotide receptors, P2Y(1) and P2Y(2) are involved in calcium signalling in glioma C6 cells. British journal of pharmacology 20010101
The critical role of adenosine and guanosine in the affinity of dinucleoside polyphosphates to P(2X)-receptors in the isolated perfused rat kidney. British journal of pharmacology 20010101
Neural mechanisms underlying migrating motor complex formation in mouse isolated colon. British journal of pharmacology 20010101
Heterogeneous calcium responses to extracellular ATP in cultured rat renal tubule cells. Clinica chimica acta; international journal of clinical chemistry 20010101
A reexamination of PSC 833 (Valspodar) as a cytotoxic agent and in combination with anticancer agents. Cancer chemotherapy and pharmacology 20010101
Co-transmitter function of ATP in central catecholaminergic neurons of the rat. Neuroscience 20010101
Early elicitor-induced events in chickpea cells: functional links between oxidative burst, sequential occurrence of extracellular alkalinisation and acidification, K+/H+ exchange and defence-related gene activation. Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
Stimulation of mouse cultured sympathetic neurons by uracil but not adenine nucleotides. Neuroscience 20010101
Protective action of the serine protease inhibitor N-tosyl-L-lysine chloromethyl ketone (TLCK) against acute soman poisoning. Journal of applied toxicology : JAT 20010101
Suramin to enhance glaucoma filtering procedures: a clinical comparison with mitomycin. Ophthalmic surgery and lasers 20010101
Excitatory effect of ATP on acutely dissociated ventromedial hypothalamic neurons of the rat. Neuroscience 20010101
Evidence for the involvement of purinergic signalling in the control of respiration. Neuroscience 20010101
Pre- and postsynaptic actions of ATP on neurotransmission in rat submandibular ganglia. Neuroscience 20010101
Depletion of substance P from rat primary sensory neurons by ATP, an implication of P2X receptor-mediated release of substance P. Neuroscience 20010101
Macrofilaricides and onchocerciasis control, mathematical modelling of the prospects for elimination. BMC public health 20010101
Update on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancer. Breast cancer research : BCR 20010101
An ex vivo angiogenesis assay utilizing commercial porcine carotid artery: modification of the rat aortic ring assay. Angiogenesis 20010101
Requirement for ERK activation in cisplatin-induced apoptosis. The Journal of biological chemistry 20001215
Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells. Cancer research 20001001
Synthesis of single- and double-chain fluorocarbon and hydrocarbon galactosyl amphiphiles and their anti-HIV-1 activity. Carbohydrate research 20000724
Activity of standard and investigational cytotoxic drugs in primary cultures of tumor cells from patients with kidney and urinary bladder carcinomas. The Journal of urology 19991201
Pharmacological characterization of the human P2Y11 receptor. British journal of pharmacology 19991101
Assessment of drugs against Cryptosporidium parvum using a simple in vitro screening method. FEMS microbiology letters 19990915
Allosteric control of gating and kinetics at P2X(4) receptor channels. The Journal of neuroscience : the official journal of the Society for Neuroscience 19990901
Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5. The Journal of biological chemistry 19990702
Human P2Y2 receptor polymorphism: identification and pharmacological characterization of two allelic variants. British journal of pharmacology 19990601
Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Molecular and cellular biology 19980901
Suramin analogues with a 2-phenylbenzimidazole moiety as partial structure; potential anti HIV- and angiostatic drugs, 2: Sulfanilic acid-, benzenedisulfonic acid-, and naphthalenetrisulfonic acid analogues. Archiv der Pharmazie 19980301
Calcium- and calmodulin-dependent PMA-activation of the CD44 adhesion molecule. Cell adhesion and communication 19980101
In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora. Journal of natural products 19970901
Inhibition of HIV-1, HIV-2 and SIV envelope glycoprotein-mediated cell fusion by calmodulin. Virus research 19970801
An examination of deoxyadenosine 5'(alpha-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor. British journal of pharmacology 19970501
Synthetic soluble analogs of galactosylceramide (GalCer) bind to the V3 domain of HIV-1 gp120 and inhibit HIV-1-induced fusion and entry. The Journal of biological chemistry 19970314
Triazine dyes inhibit HIV-1 entry by binding to envelope glycoproteins. Microbiology and immunology 19970101
Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. Research in virology 19970101
Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules. Proceedings of the National Academy of Sciences of the United States of America 19960903
Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion. Cancer research 19960801
Mechanisms of inhibition of IL-6-mediated immunoglobulin secretion by dexamethasone and suramin in human lymphoid and myeloma cell lines. Leukemia & lymphoma 19960401
Dexamethasone and suramin inhibit cell proliferation and interleukin-6-mediated immunoglobulin secretion in human lymphoid and multiple myeloma cell lines. Leukemia & lymphoma 19950501
Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells. The Journal of biological chemistry 19940930
Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction. Archives of biochemistry and biophysics 19930901
Structure-activity relationship studies with symmetric naphthalenesulfonic acid derivatives. Synthesis and influence of spacer and naphthalenesulfonic acid moiety on anti-HIV-1 activity. Journal of medicinal chemistry 19930709
Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse transcriptase and suppress human and feline immunodeficiency virus expression in cultured cells. Journal of cellular biochemistry 19930401
Selective inhibition of human cytomegalovirus replication by naphthalenedisulfonic acid derivatives. Antiviral research 19930301
Increased expression of fibroblast growth factors (FGFs) and their receptor by protamine and suramin on Kaposi's sarcoma-derived cells. Anticancer research 19930101
Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. Journal of medicinal chemistry 19921225
Sulfonic acid polymers as a new class of human immunodeficiency virus inhibitors. Antiviral research 19920601
Sulfonic acid dyes: inhibition of the human immunodeficiency virus and mechanism of action. Journal of acquired immune deficiency syndromes 19920101
Novel naphthalenedisulfonic acid anti-HIV-1 agents. Synthesis and activity against reverse transcriptase, virus replication and syncytia formation. Drug design and discovery 19911101
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives. Proceedings of the National Academy of Sciences of the United States of America 19910215
Potential anti-AIDS agents. Synthesis and antiviral activity of naphthalenesulfonic acid derivatives against HIV-1 and HIV-2. Journal of medicinal chemistry 19910101
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of natural products 19910101
Effects of suramin, an anti-human immunodeficiency virus reverse transcriptase agent, on protein kinase C. Differential activation and inhibition of protein kinase C isozymes. The Journal of biological chemistry 19900405
Inhibition of human immunodeficiency virus type 1 RNase H by sulfated polyanions. Journal of virology 19891201
In vitro anti-HIV-1 activity of chondroitin polysulphate. AIDS (London, England) 19890701
Comparison of inhibitory activities of various antiretroviral agents against particle-derived and recombinant human immunodeficiency virus type 1 reverse transcriptases. Antimicrobial agents and chemotherapy 19890101
Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. Journal of acquired immune deficiency syndromes 19890101
Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent. Proceedings of the National Academy of Sciences of the United States of America 19890101
Fuchsin acid selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochemical and biophysical research communications 19880930
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19880801
Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells. Science (New York, N.Y.) 19880429
Inhibition of HIV-1 RNA-dependent DNA polymerase and cellular DNA polymerases alpha, beta and gamma by phosphonoformic acid and other drugs. The Journal of antimicrobial chemotherapy 19880201
Inhibition of human immunodeficiency virus type I reverse transcriptase by suramin-related compounds. The Journal of general virology 19870801
Effect of retinoic acid on the replication of human immunodeficiency virus in HTLV-I-positive MT-4 cells. Medical microbiology and immunology 19870101
In vitro suppression of HTLV-III/LAV infectivity by a combination of acyclovir and suramin. The Journal of infectious diseases 19861201
Aurintricarboxylic acid and Evans Blue represent two different classes of anionic compounds which selectively inhibit the cytopathogenicity of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus. Biochemical and biophysical research communications 19860414
Comparative inhibitory effects of suramin and other selected compounds on the infectivity and replication of human T-cell lymphotropic virus (HTLV-III)/lymphadenopathy-associated virus (LAV). International journal of cancer 19860315
Screening for new compounds with antiherpes activity. Antiviral research 19841001
Aromatic sulfonic acids as viral inhibitors. Structure-activity study using rhino, adeno 3, herpes simplex, and influenza viruses. Journal of medicinal chemistry 19710701

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