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CAS No: 144298-62-4 Catalog No: AG001J98 MDL No:
Title | Journal |
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Interaction between VEGF and calcium-independent phospholipase A2 in proliferation and migration of retinal pigment epithelium. | Current eye research 20120601 |
Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids. | The Journal of biological chemistry 20120427 |
Group VIA phospholipase A2 is a target for vasopressin signaling in the thick ascending limb. | American journal of physiology. Renal physiology 20120401 |
The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction. | American journal of physiology. Cell physiology 20120401 |
Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling. | The Journal of biological chemistry 20120217 |
Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels. | The Journal of pharmacology and experimental therapeutics 20111101 |
GVI phospholipase A2 role in the stimulatory effect of sphingosine-1-phosphate on TRPC5 cationic channels. | Cell calcium 20111001 |
Combination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer development. | The American journal of pathology 20110701 |
Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance. | Journal of lipid research 20110601 |
Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle. | Aging 20110601 |
Role of calcium independent phospholipase A2 in maintaining mitochondrial membrane potential and preventing excessive exocytosis in PC12 cells. | Neurochemical research 20110201 |
Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain. | The Journal of pharmacology and experimental therapeutics 20100501 |
Calcium-independent phospholipase A(2) plays a key role in the endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. | American journal of physiology. Heart and circulatory physiology 20100401 |
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity. | Molecular pain 20100101 |
TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent. | Biochimica et biophysica acta 20091001 |
Calcium-independent phospholipase A2 beta is dispensable in inflammasome activation and its inhibition by bromoenol lactone. | Journal of innate immunity 20091001 |
Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells. | Cell calcium 20090801 |
Calcium-independent phospholipase A2 participates in KCl-induced calcium sensitization of vascular smooth muscle. | Cell calcium 20090701 |
Inhibition of calcium-independent phospholipase A2 prevents inflammatory mediator production in pulmonary microvascular endothelium. | Respiratory physiology & neurobiology 20090227 |
Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta. | The Journal of biological chemistry 20081205 |
The cytotoxic effect of bromoenol lactone, a calcium-independent phospholipase A2 inhibitor, on rat cortical neurons in culture. | Cellular and molecular neurobiology 20081201 |
Calcium-independent phospholipase A2 in rabbit ventricular myocytes. | Lipids 20080901 |
Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury. | Chemico-biological interactions 20080811 |
Complex regulation of store-operated Ca2+ entry pathway by PKC-epsilon in vascular SMCs. | American journal of physiology. Cell physiology 20080601 |
Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL). | Journal of hepatology 20080301 |
Inhibition of calcium-independent phospholipase A impairs agonist-induced calcium entry in keratinocytes. | The British journal of dermatology 20080101 |
A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells. | The Journal of biological chemistry 20070713 |
The transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activity. | Journal of lipid research 20070701 |
Activation and inactivation of the volume-sensitive taurine leak pathway in NIH3T3 fibroblasts and Ehrlich Lettre ascites cells. | American journal of physiology. Cell physiology 20070701 |
Agonist-induced calcium entry correlates with STIM1 translocation. | Journal of cellular physiology 20070601 |
Role of Ca2+-independent phospholipase A2gamma in Ca2+-induced mitochondrial permeability transition. | The Journal of pharmacology and experimental therapeutics 20070501 |
Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx. | Cell calcium 20070201 |
Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. | Toxicology 20070105 |
Calcium-independent phospholipase A2-catalyzed plasmalogen hydrolysis in hypoxic human coronary artery endothelial cells. | American journal of physiology. Cell physiology 20070101 |
Phospholipase A2-catalyzed hydrolysis of plasmalogen phospholipids in thrombin-stimulated human platelets. | Thrombosis research 20070101 |
Calcium-independent phospholipase A(2) influences AMPA-mediated toxicity of hippocampal slices by regulating the GluR1 subunit in synaptic membranes. | Hippocampus 20070101 |
Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells. | International journal of toxicology 20070101 |
Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts. | American journal of physiology. Cell physiology 20061201 |
Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent. | The Journal of biological chemistry 20061103 |
Prostacyclin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 and cyclooxygenase inhibitors. | The Journal of urology 20061001 |
Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers. | Journal of cell science 20060915 |
Highly selective hydrolysis of fatty acyl-CoAs by calcium-independent phospholipase A2beta. Enzyme autoacylation and acyl-CoA-mediated reversal of calmodulin inhibition of phospholipase A2 activity. | The Journal of biological chemistry 20060609 |
Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. | Cancer research 20060315 |
Calcium-independent phospholipase A2 modulates cytosolic oxidant activity and contractile function in murine skeletal muscle cells. | Journal of applied physiology (Bethesda, Md. : 1985) 20060201 |
A bromoenol lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiols. | Biochemistry 20060124 |
A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | Angewandte Chemie (International ed. in English) 20060109 |
A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation. | The European journal of neuroscience 20060101 |
Potential role for mast cell tryptase in recruitment of inflammatory cells to endothelium. | American journal of physiology. Cell physiology 20051201 |
Inhibition of calcium-independent phospholipase A2 activity in rat hippocampus impairs acquisition of short- and long-term memory. | Psychopharmacology 20050901 |
Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages. | The Journal of biological chemistry 20050729 |
Ca(2+)-independent phospholipase A2 participates in the vesicular transport of milk proteins. | Biochimica et biophysica acta 20050415 |
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. | The Journal of biological chemistry 20041119 |
Contribution of lipid second messengers to the regulation of phosphatidylcholine synthesis during cell cycle re-entry. | Biochimica et biophysica acta 20041108 |
Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes. | Biochimica et biophysica acta 20041108 |
Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release. | Journal of leukocyte biology 20040901 |
Laminar flow activates peroxisome proliferator-activated receptor-gamma in vascular endothelial cells. | Circulation 20040831 |
Inactivation of endoplasmic reticulum bound Ca2+-independent phospholipase A2 in renal cells during oxidative stress. | Journal of the American Society of Nephrology : JASN 20040601 |
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. | American journal of physiology. Cell physiology 20040501 |
Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation. | Aquatic toxicology (Amsterdam, Netherlands) 20040210 |
Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta. | Biochemistry 20040203 |
Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells. | Cytokine 20040107 |
Postsynaptic injection of calcium-independent phospholipase A2 inhibitors selectively increases AMPA receptor-mediated synaptic transmission. | Hippocampus 20040101 |
Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript. | Biochemistry 20031202 |
Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201 |
Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2. | The Journal of biological chemistry 20031107 |
Dopamine D1 receptor-dependent inhibition of NaCl transport in the rat thick ascending limb: mechanism of action. | European journal of pharmacology 20030725 |
Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition. | The Journal of biological chemistry 20030620 |
Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry. | The Journal of biological chemistry 20030404 |
Phospholipase A2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis. | Journal of cellular and molecular medicine 20030101 |
Phospholipid metabolite production in human urothelial cells after protease-activated receptor cleavage. | American journal of physiology. Renal physiology 20021101 |
Essential role of Ca2+ -dependent phospholipase A2 in estradiol-induced lysosome activation. | American journal of physiology. Cell physiology 20021101 |
Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression. | The Journal of biological chemistry 20021011 |
Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s. | The Journal of biological chemistry 20020906 |
Calcium-independent phospholipase A(2)-derived arachidonic acid is essential for endothelium-dependent relaxation by acetylcholine. | The Journal of pharmacology and experimental therapeutics 20020901 |
Enzymatic properties of human cytosolic phospholipase A(2)gamma. | The Journal of biological chemistry 20020816 |
Pore formation and uncoupling initiate a Ca2+-independent degradation of mitochondrial phospholipids. | Biochemistry 20020618 |
Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent. | Biochemical pharmacology 20020615 |
Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors. | Biochemical pharmacology 20020115 |
A calcium-independent phospholipase activity insensitive to bromoenol lactone mediates arachidonic acid release by lindane in rat myometrial cells. | Life sciences 20011214 |
Endothelial cell PAF synthesis following thrombin stimulation utilizes Ca(2+)-independent phospholipase A(2). | Biochemistry 20011211 |
Proliferative and morphological effects of endothelins in Schwann cells: roles of p38 mitogen-activated protein kinase and Ca(2+)-independent phospholipase A2. | Journal of neurochemistry 20011201 |
Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. | Journal of immunology (Baltimore, Md. : 1950) 20010915 |
Calcium-independent phospholipase A(2) mediates CREB phosphorylation and c-fos expression during ischemia. | American journal of physiology. Heart and circulatory physiology 20010701 |
Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of proliferating T cells to CoA-independent transacyclase inhibitor-induced apoptosis. | The Journal of biological chemistry 20010518 |
Clinical concentrations of doxorubicin inhibit activity of myocardial membrane-associated, calcium-independent phospholipase A(2). | Cancer research 20010515 |
The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway. | The Journal of biological chemistry 20010427 |
Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2beta. | The Journal of biological chemistry 20010420 |
Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm. | Biochemical and biophysical research communications 20010223 |
Oxidant-induced inhibition of myocardial calcium-independent phospholipase A2. | Cardiovascular toxicology 20010101 |
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