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Home > Imidazoles > 143945-86-2
CAS No: 143945-86-2 Catalog No: AG007J9P MDL No:
Title | Journal |
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Ozagrel for acute ischemic stroke: a meta-analysis of data from randomized controlled trials. | Neurological research 20120501 |
Synthesis, crystal structure, and properties of a double-helical zinc(II) coordination polymer with Ozagrel drug. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201 |
Sulfotanshinone sodium injection for unstable angina pectoris: a systematic review of randomized controlled trials. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Fasudil and ozagrel in combination show neuroprotective effects on cerebral infarction after murine middle cerebral artery occlusion. | The Journal of pharmacology and experimental therapeutics 20110701 |
Poly[{μ(3)-3-[4-(1H-imidazol-1-yl-methyl)phen-yl]prop-2-enoato-κN:η:κO}copper(I)]. | Acta crystallographica. Section E, Structure reports online 20110501 |
[Effect of TXA2 inhibitor on the proliferation and apoptosis of hypoxic pulmonary artery smooth muscle cells of porcines]. | Zhonghua yi xue za zhi 20110125 |
Thromboxane-prostanoid receptor expression and antagonism in dextran-sodium sulfate-induced colitis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110101 |
Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer. | Molecular cancer 20110101 |
The inhibitory effect of non-steroidal anti-inflammatory drugs (NSAIDs) on the monophenolase and diphenolase activities of mushroom tyrosinase. | International journal of molecular sciences 20110101 |
Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide. | PloS one 20110101 |
Bihemispheric subcortical infarcts in the middle cerebral artery territory. | Clinical medicine insights. Case reports 20110101 |
Ghrelin signaling in human mesenteric arteries. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100801 |
Sildenafil attenuates pulmonary arterial pressure but does not improve oxygenation during ARDS. | Intensive care medicine 20100501 |
Thromboxane A(2) promotes soluble CD40 ligand release from human platelets. | Atherosclerosis 20100401 |
The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1. | Brain, behavior, and immunity 20100301 |
A prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20100201 |
[The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. | Zhonghua yi xue za zhi 20100126 |
Integrative meta-analysis of differential gene expression in acute myeloid leukemia. | PloS one 20100101 |
Platelet function and spontaneous thrombolytic activity of patients with cerebral infarction assessed by the global thrombosis test. | Pathophysiology of haemostasis and thrombosis 20100101 |
Polychlorinated biphenyls (PCBs) enhance metastatic properties of breast cancer cells by activating Rho-associated kinase (ROCK). | PloS one 20100101 |
Hypersensitivity to thromboxane receptor mediated cerebral vasomotion and CBF oscillations during acute NO-deficiency in rats. | PloS one 20100101 |
Effect of combination therapy with sodium ozagrel and panax ginseng on transient cerebral ischemia model in rats. | Journal of biomedicine & biotechnology 20100101 |
A selective thromboxane A2 (TXA2) synthase inhibitor, ozagrel, attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in oleic acid-induced lung injury in guinea pigs. | Journal of pharmacological sciences 20091001 |
[Effects of sodium ozagrel in primary thrombocytosis combined with thrombosis]. | Zhongguo shi yan xue ye xue za zhi 20091001 |
Thromboxane A(2) contributes to the mediation of flow-induced responses of skeletal muscle venules: role of cyclooxygenases 1 and 2. | Journal of vascular research 20090801 |
Abnormalities of endothelium-dependent responses in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats are improved by chronic treatment with thromboxane A2 synthase inhibitor. | Atherosclerosis 20090701 |
Retinal artery embolization during carotid angioplasty and carotid artery stenting: case report. | Neurologia medico-chirurgica 20090501 |
In vitro effect of ozagrel on mushroom tyrosinase. | The protein journal 20090501 |
Edaravone (radical scavenger) versus sodium ozagrel (antiplatelet agent) in acute noncardioembolic ischemic stroke (EDO trial). | Cerebrovascular diseases (Basel, Switzerland) 20090101 |
NK1 receptor-mediated endothelium-dependent relaxation and contraction with different sensitivity to post-receptor signaling in pulmonary arteries. | Vascular pharmacology 20090101 |
Chronic recanalization of dissection of the distal anterior cerebral artery: case report and review of the literature. | Case reports in medicine 20090101 |
Ozagrel reverses streptozotocin-induced constriction of arterioles in rat retina. | Microvascular research 20081101 |
[Diagnosis and management for acute ischemic stroke]. | Rinsho shinkeigaku = Clinical neurology 20081101 |
Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis. | Circulation research 20081024 |
Inhibition of TXA synthesis with OKY-046 improves liver preservation by prolonged hypothermic machine perfusion in rats. | Journal of gastroenterology and hepatology 20080701 |
Losartan and ozagrel reverse retinal arteriolar constriction in non-obese diabetic mice. | Microcirculation (New York, N.Y. : 1994) 20080701 |
Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. | Shock (Augusta, Ga.) 20080601 |
Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice--possible dysfunction of receptor and/or receptor-G protein coupling. | Naunyn-Schmiedeberg's archives of pharmacology 20080601 |
Safety and efficacy of fasudil monotherapy and fasudil-ozagrel combination therapy in patients with subarachnoid hemorrhage: sub-analysis of the post-marketing surveillance study. | Neurologia medico-chirurgica 20080601 |
Ozagrel attenuates early streptozotocin-induced constriction of arterioles in the mouse retina. | Experimental eye research 20080301 |
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents. | Oncogene 20080103 |
Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep. | Critical care (London, England) 20080101 |
Effect of sodium ozagrel on the activity of rat CYP2D6. | European journal of pharmacology 20071114 |
[Adverse effects of thromboxane receptor antagonists and synthase inhibitors]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
Involvement of inducible nitric oxide synthase in blood flow decrease in vein induced by hen-egg white lysozyme. | Biological & pharmaceutical bulletin 20070701 |
Cyclooxygenase-1 is involved in endothelial dysfunction of mesenteric small arteries from angiotensin II-infused mice. | Hypertension (Dallas, Tex. : 1979) 20070301 |
Mediators of CD18/P-selectin-dependent constriction of venule-paired arterioles in hypercholesterolemia. | Microvascular research 20070301 |
Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. | Vascular pharmacology 20070201 |
Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils. | Brain research 20070112 |
[Antiplatelet therapy for acute ischemic stroke]. | Nihon rinsho. Japanese journal of clinical medicine 20061128 |
[Cerebral infarction]. | Nihon rinsho. Japanese journal of clinical medicine 20061101 |
Effect of a selective thromboxane A2 synthetase inhibitor on the systemic changes induced by circulating pancreatic phospholipase A2. | Journal of gastroenterology 20061101 |
[Sodium ozagrel]. | Nihon rinsho. Japanese journal of clinical medicine 20061028 |
Potentiation by neuropeptide Y of 5HT2A receptor-mediated contraction in porcine coronary artery. | European journal of pharmacology 20060821 |
Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vascular preparations. | The Journal of pharmacology and experimental therapeutics 20060501 |
Prostanoids as pharmacological targets in COPD and asthma. | European journal of pharmacology 20060308 |
Edaravone diminishes free radicals from circulating neutrophils in patients with ischemic brain attack. | Internal medicine (Tokyo, Japan) 20060101 |
Evidence for the involvement of the cyclooxygenase-metabolic pathway in diclofenac-induced inhibition of spontaneous contraction of rat portal vein smooth muscle cells. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20050801 |
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury. | Anesthesiology 20050501 |
Prominent unilateral convergence palsy in a patient with a tiny dorsal midbrain infarction. | European neurology 20050101 |
Role of leukotriene receptor antagonists in the treatment of exercise-induced bronchoconstriction: a review. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20050101 |
Higher viscosity participates in the regulation of coronary flow via nitric oxide and indomethacin-sensitive contracting factor. | Canadian journal of physiology and pharmacology 20041201 |
[Clinical guidelines for stroke]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20041110 |
Restoration of middle cerebral artery thrombosis by novel glycoprotein IIb/IIIa antagonist FK419 in guinea pig. | European journal of pharmacology 20040913 |
Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. | The Journal of pharmacy and pharmacology 20040401 |
Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. | The Journal of pharmacology and experimental therapeutics 20040301 |
Different prostanoids are involved in bradykinin-induced endothelium-dependent and -independent vasoconstriction in rat mesenteric resistance arteries. | Journal of pharmacological sciences 20040201 |
Protective effect of FK506 and thromboxane synthase inhibitor on ischemia-reperfusion injury in non-heart-beating donor in rat orthotopic liver transplantation. | The journal of medical investigation : JMI 20040201 |
Role of thromboxane derived from COX-1 and -2 in hepatic microcirculatory dysfunction during endotoxemia in mice. | Hepatology (Baltimore, Md.) 20040101 |
Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells. | Biological & pharmaceutical bulletin 20031201 |
Rhythmical contractions in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats. | Pflugers Archiv : European journal of physiology 20031101 |
[The clinical effect of combination therapy with edaravone and sodium ozagrel for acute cerebral infarction]. | No to shinkei = Brain and nerve 20030701 |
Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. | American journal of physiology. Heart and circulatory physiology 20030601 |
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats. | Life sciences 20030502 |
Dissecting aneurysm of the anterior cerebral artery with severe subarachnoid hemorrhage during treatment for cerebral infarction. | Internal medicine (Tokyo, Japan) 20030501 |
Endothelium-derived prostaglandin H2 evokes the stretch-induced contraction of rabbit pulmonary artery. | European journal of pharmacology 20030425 |
Effect of TTC-909 on cerebral infarction following permanent occlusion of the middle cerebral artery in stroke prone spontaneously hypertensive rats. | Journal of pharmacological sciences 20030401 |
Role of intracellular Ca2+ in endothelium-dependent contraction and relaxation of rabbit intrapulmonary arteries. | Life sciences 20030307 |
Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion-induced hepatic microcirculatory dysfunction in mice. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20030101 |
[A 50-year history of new drugs in Japan-the development and trends of hemostatics and antithrombotic drugs]. | Yakushigaku zasshi 20030101 |
Effect of ozagrel, a selective thromboxane A2-synthetase inhibitor, on cerebral infarction in rats. Comparative study with norphenazone, a free-radical scavenger. | Arzneimittel-Forschung 20030101 |
The effect of ozagrel sodium on photochemical thrombosis in rat: therapeutic window and combined therapy with heparin sodium. | Life sciences 20021108 |
Intracoronary administration of a thromboxane A2 synthase inhibitor relieves acetylcholine-induced coronary spasm. | Circulation journal : official journal of the Japanese Circulation Society 20020901 |
[A case of migrainous infarction accompanying idiopathic thrombocytopenic purpura]. | Rinsho shinkeigaku = Clinical neurology 20020901 |
Effect of TTC-909 in a middle cerebral artery thrombosis model in stroke-prone spontaneously hypertensive rats. | European journal of pharmacology 20020802 |
Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction. | European journal of pharmacology 20020517 |
Semiquantitative dynamic computed tomography to predict response to anti-platelet therapy in acute cerebral infarction. | Neuroradiology 20020401 |
Effect of ozagrel hydrochloride, a thromboxane synthetase inhibitor, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. | Prostaglandins, leukotrienes, and essential fatty acids 20020401 |
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets. | Thrombosis and haemostasis 20020101 |
Thromboxane A2 inhibition: therapeutic potential in bronchial asthma. | American journal of respiratory medicine : drugs, devices, and other interventions 20020101 |
[Strategy for circulatory disturbance]. | Rinsho shinkeigaku = Clinical neurology 20011201 |
[Thromboxane A2 synthase inhibitor and receptor antagonist]. | Nihon rinsho. Japanese journal of clinical medicine 20011001 |
Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage. | Life sciences 20010810 |
Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia. | Brain research 20010601 |
[Endothelin receptor antagonist, phosphodiesterase inhibitor, thromboxane inhibitor]. | Nihon rinsho. Japanese journal of clinical medicine 20010601 |
The combined use of prostaglandin I2 analogue (OP-2507) and thromboxane A2 synthetase inhibitor (OKY-046) strongly inhibits atherosclerosis of aortic allografts in rats. | Surgery 20010501 |
Effect of thromboxane A2 (TXA2) synthase inhibitor and TXA2 receptor antagonist alone and in combination on antigen-induced bronchoconstriction in guinea pigs. | Prostaglandins & other lipid mediators 20010501 |
A novel series of thromboxane A2 synthetase inhibitors with free radical scavenging and anti-peroxidative activities. | Chemical & pharmaceutical bulletin 20010501 |
Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20010501 |
Thromboxane A(2) synthase inhibitor enhanced antithrombotic efficacy of GPIIb-IIIa receptor antagonist without increasing bleeding. | European journal of pharmacology 20010413 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats. | Journal of hypertension 20010301 |
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