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14278-49-0

14278-49-0 | N-{3-[(4-aminobutyl)amino]propyl}acetamideHCl

CAS No: 14278-49-0 Catalog No: AG003SNE MDL No:

Product Description

Catalog Number:
AG003SNE
Chemical Name:
N-{3-[(4-aminobutyl)amino]propyl}acetamideHCl
CAS Number:
14278-49-0
IUPAC Name:
N-[3-(4-aminobutylamino)propyl]acetamide
InChI:
InChI=1S/C9H21N3O/c1-9(13)12-8-4-7-11-6-3-2-5-10/h11H,2-8,10H2,1H3,(H,12,13)
InChI Key:
MQTAVJHICJWXBR-UHFFFAOYSA-N

Properties

Complexity:
128  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
187.168g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
187.287g/mol
Monoisotopic Mass:
187.168g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
67.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.8  

Literature

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Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression. PLoS pathogens 20120101
The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism. Journal of medicinal chemistry 20110714
Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants. Cancer chemotherapy and pharmacology 20110201
The structure of Helicobacter pylori HP0310 reveals an atypical peptidoglycan deacetylase. PloS one 20110101
Cellular diamine levels in cancer chemoprevention: modulation by ibuprofen and membrane plasmalogens. Lipids in health and disease 20110101
A new piece of the Shigella Pathogenicity puzzle: spermidine accumulation by silencing of the speG gene [corrected]. PloS one 20110101
Polyamine patterns in the cerebrospinal fluid of patients with Parkinson's disease and multiple system atrophy. Clinica chimica acta; international journal of clinical chemistry 20101009
Identification and determination of urinary acetylpolyamines in cancer patients by electrospray ionization and time-of-flight mass spectrometry. Analytical biochemistry 20100601
Growth-related changes in intracellular spermidine and its effect on efflux pump expression and quorum sensing in Burkholderia pseudomallei. Microbiology (Reading, England) 20100401
Polyamine catabolism is enhanced after traumatic brain injury. Journal of neurotrauma 20100301
Simultaneous determination of different polyamines and their mono-acetylated derivatives in gastric tissue by HPLC with post-column derivatization. Scientia pharmaceutica 20100101
Serum polyamines in pre- and post-operative patients with breast cancer corrected by menopausal status. Cancer letters 20090118
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. PLoS genetics 20090101
Analysis of polyamines as carbamoyl derivatives in urine and serum by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC 20080101
The concept of 'aldehyde load' in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line. Brain research 20070511
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. International journal of oncology 20061201
Cloning of the bovine prion-like Shadoo (SPRN) gene by comparative analysis of the predicted genomic locus. Mammalian genome : official journal of the International Mammalian Genome Society 20061101
Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase. The Journal of biological chemistry 20060224
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis. Nutrition and cancer 20060101
Polyamines biosynthesis and oxidation in free-living amoebae. Amino acids 20041201
Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates. Biochemical and biophysical research communications 20041119
Accumulation of spermidine/spermine N1-acetyltransferase and alternatively spliced mRNAs as a delayed response of HeLa S3 cells following X-ray irradiation. International journal of radiation biology 20040501
Effect of diethylstilbestrol on polyamine metabolism in hamster epididymis. Asian journal of andrology 20031201
Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase. The Journal of biological chemistry 20030606
Decrease in cell viability in an RMF, sigma(38), and OmpC triple mutant of Escherichia coli. Biochemical and biophysical research communications 20021129

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