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14124-50-6

14124-50-6 | hydrochlorathiazide-triamterene

CAS No: 14124-50-6 Catalog No: AG009WGD MDL No:

Product Description

Catalog Number:
AG009WGD
Chemical Name:
hydrochlorathiazide-triamterene
CAS Number:
14124-50-6
IUPAC Name:
6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;6-phenylpteridine-2,4,7-triamine
InChI:
InChI=1S/C12H11N7.C7H8ClN3O4S2/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9;8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-5H,(H6,13,14,15,17,18,19);1-2,10-11H,3H2,(H2,9,12,13)
InChI Key:
XZRKEDHJXXLVSK-UHFFFAOYSA-N

Properties

Complexity:
801  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
550.072g/mol
Formal Charge:
0
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
550.997g/mol
Monoisotopic Mass:
550.072g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
265A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

Title Journal
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients. The Cochrane database of systematic reviews 20120815
Bioequivalence evaluation of a triamterene-hydrochlorothiazide generic product: a new bioequivalence index for fixed-dose combinations. Regulatory toxicology and pharmacology : RTP 20110201
Thiazide-induced lichenoid photosensitivity. Clinical and experimental dermatology 20021101
Nephrogenic diabetes insipidus persisting 57 months after cessation of lithium carbonate therapy: report of a case and review of the literature. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20000101
Clarithromycin-induced delirium in a general hospital. Psychosomatics 19980101
Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene. Journal of the American Society of Nephrology : JASN 19950601
Omeprazole-induced acute interstitial nephritis. The American journal of medicine 19930801
Verapamil caused depression, confusion, and impotence. The American journal of psychiatry 19880301
Dyazide-induced reversible acute renal failure associated with intracellular crystal deposition. American journal of kidney diseases : the official journal of the National Kidney Foundation 19861201
Renal failure with potassium-sparing diuretics. The New Zealand medical journal 19850814
Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide. Lancet (London, England) 19850713
The short-term effects of reducing elevated blood pressure in elderly patients with propranolol and dyazide. Age and ageing 19840301
Thiazide-induced hyponatremia. Southern medical journal 19831101
Amantadine-dyazide interaction. Canadian Medical Association journal 19831101
Visual hallucinations as the earliest symptom of digoxin intoxication. Archives of neurology 19830601
Drug-induced acute interstitial nephritis with granulomas. Human pathology 19830101
Risk of kidney stones. JAMA 19821022
Lithium intoxication and its clinical management. Southern medical journal 19820601
[Acute kidney failure caused by triamterene and hydrochlorothiazide]. Deutsche medizinische Wochenschrift (1946) 19820528
Prazosin as cause of urinary incontinence. Urology 19811201
Nephrogenic diabetes insipidus associated with Dyazide (triamterene-hydrochlorothiazide). British medical journal (Clinical research ed.) 19811031
Triamterene nephrolithiasis complicating dyazide therapy. The Journal of urology 19810801
Triamterene-induced nephrolithiasis. JAMA 19810626
Triamterene urolithiasis. Canadian Medical Association journal 19810615
Acute interstitial nephritis associated with thiazide diuretics. Clinical and pathologic observations in three cases. The American journal of medicine 19801201
Triamterene nephrolithiasis. JAMA 19801128
Diuretic-induced renal colic. JAMA 19730820

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