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14075-00-4

14075-00-4 | D-Ribofuranose, 1-(dihydrogen phosphate)

CAS No: 14075-00-4 Catalog No: AG001CR7 MDL No:

Product Description

Catalog Number:
AG001CR7
Chemical Name:
D-Ribofuranose, 1-(dihydrogen phosphate)
CAS Number:
14075-00-4
Molecular Formula:
C14H18ClNO
Molecular Weight:
251.7518
IUPAC Name:
[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl] dihydrogen phosphate
InChI:
InChI=1S/C5H11O8P/c6-1-2-3(7)4(8)5(12-2)13-14(9,10)11/h2-8H,1H2,(H2,9,10,11)/t2-,3-,4-,5?/m1/s1
InChI Key:
YXJDFQJKERBOBM-SOOFDHNKSA-N
SMILES:
ClCC(=O)N1c2ccccc2[C@H](CC1(C)C)C

Properties

Complexity:
238  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
230.019g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
230.109g/mol
Monoisotopic Mass:
230.019g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
137A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.1  

Literature

Title Journal
Uridine phosphorylase from Trypanosoma cruzi: kinetic and chemical mechanisms. Biochemistry 20111025
The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases. Biochemistry 20110802
Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate. Journal of synchrotron radiation 20110101
The kinetic mechanism of human uridine phosphorylase 1: Towards the development of enzyme inhibitors for cancer chemotherapy. Archives of biochemistry and biophysics 20100501
Punching holes in an enzyme. Chemistry & biology 20090925
Ribocation transition state capture and rebound in human purine nucleoside phosphorylase. Chemistry & biology 20090925
Redundant roles of photoreceptors and cytokinins in regulating photosynthetic acclimation to canopy density. Journal of experimental botany 20090301
AtSOFL1 and AtSOFL2 act redundantly as positive modulators of the endogenous content of specific cytokinins in Arabidopsis. PloS one 20090101
Key role of uridine kinase and uridine phosphorylase in the homeostatic regulation of purine and pyrimidine salvage in brain. Neurochemistry international 20071201
5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside stimulates tyrosine hydroxylase activity and catecholamine secretion by activation of AMP-activated protein kinase in PC12 cells. Journal of neuroendocrinology 20070801
Methods for the determination of intracellular levels of ribose phosphates. Journal of biochemical and biophysical methods 20061031
Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor. Acta crystallographica. Section F, Structural biology and crystallization communications 20060801
Phosphate activation in the ground state of purine nucleoside phosphorylase. Journal of the American Chemical Society 20060621
Efficiency of different methods of extraction and purification of cytokinins. Phytochemistry 20060601
Pentose phosphates in nucleoside interconversion and catabolism. The FEBS journal 20060301
Ectopic over-expression of the maize beta-glucosidase Zm-p60.1 perturbs cytokinin homeostasis in transgenic tobacco. Journal of experimental botany 20060101
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine. Archives of biochemistry and biophysics 20051001
The charged milieu: a major player in fertilization reactions. Acta histochemica 20040201
The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles. Cellular and molecular life sciences : CMLS 20030401
Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme. Biochimica et biophysica acta 20020603
Purine and pyrimidine salvage in whole rat brain. Utilization of ATP-derived ribose-1-phosphate and 5-phosphoribosyl-1-pyrophosphate generated in experiments with dialyzed cell-free extracts. The Journal of biological chemistry 20020322
Ligand-specific alphabeta and gammadelta T cell responses in childhood tuberculosis. The Journal of infectious diseases 20000101
Ribose-1-P is the essential precursor for nucleic acid synthesis in animal cells growing on uridine in the absence of sugar. The Journal of biological chemistry 19820310

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