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137361-05-8 | L-Ornithine, N5-[imino(propylamino)methyl]-
CAS No: 137361-05-8 Catalog No: AG00135V MDL No:MFCD01320455
Product Description
Catalog Number:
AG00135V
Chemical Name:
L-Ornithine, N5-[imino(propylamino)methyl]-
CAS Number:
137361-05-8
Molecular Formula:
C9H20N4O2
Molecular Weight:
216.2807
MDL Number:
MFCD01320455
IUPAC Name:
(2S)-2-amino-5-[(N'-propylcarbamimidoyl)amino]pentanoic acid
InChI:
InChI=1S/C9H20N4O2/c1-2-5-12-9(11)13-6-3-4-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1
InChI Key:
AOMXURITGZJPKB-ZETCQYMHSA-N
SMILES:
CCCNC(=N)NCCC[C@@H](C(=O)O)N
Properties
Complexity:
218
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
216.159g/mol
Formal Charge:
0
Heavy Atom Count:
15
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
216.285g/mol
Monoisotopic Mass:
216.159g/mol
Rotatable Bond Count:
8
Topological Polar Surface Area:
114A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.3
Literature
| Title | Journal |
|---|---|
| Selective and nonselective neuronal NOS inhibitors impair cognitive function in the three panel runway and passive avoidance tasks in rats. | Pharmacology, biochemistry, and behavior 20120601 |
| Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update. | TheScientificWorldJournal 20120101 |
| The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. | Nitric oxide : biology and chemistry 20111130 |
| Neuronal nitric oxide synthase is involved in the induction of nerve growth factor-induced neck muscle nociception. | Headache 20110501 |
| Adenosine A2A receptor activation attenuates tubuloglomerular feedback responses by stimulation of endothelial nitric oxide synthase. | American journal of physiology. Renal physiology 20110201 |
| Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats. | Journal of biomedical science 20110101 |
| Inhibition of nNOS prevents and inhibition of iNOS reverses α,β-meATP-induced facilitation of neck muscle nociception in mice. | European journal of pharmacology 20101125 |
| Cardiovascular responses to L-glutamate microinjection into the hypothalamic paraventricular nucleus are mediated by a local nitric oxide-guanylate cyclase mechanism. | Brain research 20100716 |
| Choroidal blood flow compensation in rats for arterial blood pressure decreases is neuronal nitric oxide-dependent but compensation for arterial blood pressure increases is not. | Experimental eye research 20100601 |
| Involvement of the nitric oxide/(C)GMP/K(ATP) pathway in antinociception induced by exercise in rats. | Life sciences 20100327 |
| Interaction of purinergic and nitrergic mechanisms in the caudal nucleus tractus solitarii of rats. | Autonomic neuroscience : basic & clinical 20091203 |
| Roles of nitric oxide synthase isoforms in cutaneous vasodilation induced by local warming of the skin and whole body heat stress in humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20091101 |
| Spinal ERK activation via NO-cGMP pathway contributes to nociceptive behavior induced by morphine-3-glucuronide. | Biochemical pharmacology 20091015 |
| Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator. | Journal of neuroscience research 20090815 |
| Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases. | European journal of medicinal chemistry 20090701 |
| Role of glutamate NMDA receptors and nitric oxide located within the periaqueductal gray on defensive behaviors in mice confronted by predator. | Psychopharmacology 20090701 |
| Facilitation of myocardial PI3K/Akt/nNOS signaling contributes to ethanol-evoked hypotension in female rats. | Alcoholism, clinical and experimental research 20090701 |
| Inhibiting the neuronal isoform of nitric oxide synthase has similar effects on the compensatory choroidal and axial responses to myopic defocus in chicks as does the non-specific inhibitor L-NAME. | Experimental eye research 20090601 |
| Bed nucleus of the stria terminalis N-methyl-D-aspartate receptors and nitric oxide modulate the baroreflex cardiac component in unanesthetized rats. | Journal of neuroscience research 20090515 |
| A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090401 |
| Cyclooxygenase 2 inhibition suppresses tubuloglomerular feedback: roles of thromboxane receptors and nitric oxide. | American journal of physiology. Renal physiology 20090401 |
| The influence of estrogen and progesterone on parasympathetic vasodilatation in the rat submandibular gland. | Autonomic neuroscience : basic & clinical 20090312 |
| Pharmacological assessments of nitric oxide synthase isoforms and downstream diversity of NO signaling in the maintenance of thermal and mechanical hypersensitivity after peripheral nerve injury in mice. | Neuropharmacology 20090301 |
| Inhibition of the NMDA receptor/Nitric Oxide pathway in the dorsolateral periaqueductal gray causes anxiolytic-like effects in rats submitted to the Vogel conflict test. | Behavioral and brain functions : BBF 20090101 |
| Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. | Bioorganic & medicinal chemistry 20081215 |
| Anxiogenic-like effects induced by NMDA receptor activation are prevented by inhibition of neuronal nitric oxide synthase in the periaqueductal gray in mice. | Brain research 20081113 |
| Local loperamide inhibits thermal hyperalgesia but not mechanical allodynia induced by intratibial inoculation of melanoma cells in mice. | Cellular and molecular neurobiology 20081101 |
| The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex. | Cerebral cortex (New York, N.Y. : 1991) 20080901 |
| Nitric oxide involvement in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080501 |
| Role of nitric oxide synthase/arginase balance in bronchial reactivity in patients with chronic obstructive pulmonary disease. | American journal of physiology. Lung cellular and molecular physiology 20080301 |
| Interaction between glutamatergic and nitrergic mechanisms mediating cardiovascular responses to L-glutamate injection in the diagonal band of Broca in anesthetized rats. | Life sciences 20070816 |
| Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway. | British journal of pharmacology 20070801 |
| Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. | British journal of pharmacology 20070701 |
| Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat. | Neuropharmacology 20070401 |
| CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon. | European journal of pharmacology 20070227 |
| Nitric oxide modulation of norepinephrine production in acupuncture points. | Life sciences 20061102 |
| Pentagastrin-induced nitric oxide-dependent protein secretion from the parotid gland of the anaesthetized rat. | Experimental physiology 20061101 |
| Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. | Journal of neuroscience research 20060815 |
| Pentagastrin-induced protein synthesis in the parotid gland of the anaesthetized rat, and its dependence on CCK-A and -B receptors and nitric oxide generation. | Experimental physiology 20060701 |
| Injection of l-glutamate into medial prefrontal cortex induces cardiovascular responses through NMDA receptor - nitric oxide in rat. | Neuropharmacology 20060701 |
| Striatal microinjections of nitric oxide synthase inhibitors and L-arginine fail to exert effects on paroxysmal dystonia in the dtsz mutant. | Neuroscience letters 20060501 |
| Defensive-like behaviors and antinociception induced by NMDA injection into the periaqueductal gray of mice depend on nitric oxide synthesis. | Brain research 20060303 |
| Parasympathetic nerve-evoked protein synthesis, mitotic activity and salivary secretion in the rat parotid gland and the dependence on NO-generation. | Archives of oral biology 20060301 |
| A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis. | Inflammatory bowel diseases 20060201 |
| Effects of blockade of glutamate NMDA receptors or of NO synthase on the development or the expression of associative or non-associative sensitization to locomotor activation by morphine. | Journal of neural transmission (Vienna, Austria : 1996) 20060101 |
| Medial prefrontal cortex NMDA receptors and nitric oxide modulate the parasympathetic component of the baroreflex. | The European journal of neuroscience 20060101 |
| High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L-arginine, and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent. | Journal of chromatography. A 20050225 |
| Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by NOS I and II isoforms. | Neuropharmacology 20050101 |
| The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. | European journal of pharmacology 20041025 |
| Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response. | British journal of pharmacology 20041001 |
| The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle. | Nitric oxide : biology and chemistry 20040801 |
| Nitrergic and glutamatergic neuronal mechanisms at the trigeminovascular first-order synapse. | Neuropharmacology 20040701 |
| Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase. | Journal of neuroscience research 20040615 |
| Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat. | Neuropharmacology 20040601 |
| Nitric oxide control of the dorsal aorta and the intestinal vein of the Australian short-finned eel Anguilla australis. | The Journal of experimental biology 20040301 |
| Nitric oxide-dependent protein synthesis in parotid and submandibular glands of anaesthetized rats upon sympathetic stimulation or isoprenaline administration. | Experimental physiology 20040301 |
| Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms. | The Journal of biological chemistry 20031114 |
| Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure. | Circulation research 20031003 |
| Hemispheric dissociation of the involvement of NOS isoforms in memory for discriminated avoidance in the chick. | Learning & memory (Cold Spring Harbor, N.Y.) 20030901 |
| Endothelial nitric oxide modulates perivascular sensory neurotransmission in the rat isolated mesenteric arterial bed. | British journal of pharmacology 20020901 |
| Neuronal NO modulates spontaneous and ANG II-stimulated fetal swallowing behavior in the near-term ovine fetus. | American journal of physiology. Regulatory, integrative and comparative physiology 20020501 |
| Differential contributions of nitric oxide synthase isoforms at hippocampal formation to negative feedback regulation of penile erection in the rat. | British journal of pharmacology 20020501 |
| Lack of a role of neuronal nitric oxide synthase in the regulation of the renal function in rats fed a low-sodium diet. | Kidney & blood pressure research 20020101 |
| Role of nitric oxide in ethanol-induced up-regulation of muscarinic acetylcholine receptors in SH-SY5Y cells. | Alcoholism, clinical and experimental research 20010801 |
| The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. | American journal of physiology. Regulatory, integrative and comparative physiology 20010701 |
| Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. | Journal of medicinal chemistry 19971121 |
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