CAS 137201-62-8 | L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl- | CAS Number 137201-62-8

200,000+ products from a single source!

sales@angenechem.com

Product Categories

Home > Other Building Blocks > 137201-62-8

137201-62-8 | L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-

CAS No: 137201-62-8 Catalog No: AG0012XS MDL No:

Product Description

Catalog Number:

AG0012XS

Chemical Name:

L-Threonine, L-leucyl-L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-

CAS Number:

137201-62-8

Molecular Formula:

C45H64N8O10

Molecular Weight:

877.0373

IUPAC Name:

(2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoic acid

InChI:

InChI=1S/C45H64N8O10/c1-23(2)19-31(46)39(56)50-37(25(5)6)43(60)51-36(24(3)4)42(59)49-34(20-27-14-16-29(55)17-15-27)44(61)53-18-10-13-35(53)41(58)48-33(40(57)52-38(26(7)54)45(62)63)21-28-22-47-32-12-9-8-11-30(28)32/h8-9,11-12,14-17,22-26,31,33-38,47,54-55H,10,13,18-21,46H2,1-7H3,(H,48,58)(H,49,59)(H,50,56)(H,51,60)(H,52,57)(H,62,63)/t26-,31+,33+,34+,35+,36+,37+,38+/m1/s1

InChI Key:

BXIFNVGZIMFBQB-DYDSHOKNSA-N

SMILES:

CC(C[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](O)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)C(C)C)C(C)C)N)C

Properties

Complexity:

1590

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

876.475g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

877.053g/mol

Monoisotopic Mass:

876.475g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

285A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

Literature

Title	Journal
Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist.	Journal of medicinal chemistry 20070906
Spinorphin as an endogenous inhibitor of enkephalin-degrading enzymes: roles in pain and inflammation.	Current protein & peptide science 20021201
The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR.	Journal of immunology (Baltimore, Md. : 1950) 20011201
Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice.	Japanese journal of pharmacology 20011201
Identification of dipeptidyl peptidase III in human neutrophils.	Biochemical and biophysical research communications 20000705
Inhibitory effects of spinorphin, a novel endogenous regulator, on chemotaxis, O2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils.	Biochemical pharmacology 19970915
Reversed-phase high-performance liquid chromatography for the determination of haemorphin-like immunoreactivity in human cerebrospinal fluid.	Journal of chromatography. A 19940729
A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family.	The Journal of biological chemistry 19920415