200,000+ products from a single source!
sales@angenechem.com
136676-91-0 | 1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)-, 2,2,2-trifluoroacetate (1:2)
CAS No: 136676-91-0 Catalog No: AG001274 MDL No:MFCD11046022
Product Description
Catalog Number:
AG001274
Chemical Name:
1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)-, 2,2,2-trifluoroacetate (1:2)
CAS Number:
136676-91-0
Molecular Formula:
C35H34F6N4O7
Molecular Weight:
736.6575
MDL Number:
MFCD11046022
IUPAC Name:
(6S)-1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid;2,2,2-trifluoroacetic acid
InChI:
InChI=1S/C31H32N4O3.2C2HF3O2/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24;2*3-2(4,5)1(6)7/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38);2*(H,6,7)/t28-;;/m0../s1
InChI Key:
GPKQIEZLHVGJQH-ZXVJYWQYSA-N
SMILES:
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)[C@@H]1Cc2c(CN1C(=O)C(c1ccccc1)c1ccccc1)ncn2Cc1ccc(c(c1)C)N(C)C
Properties
Complexity:
874
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
736.233g/mol
Formal Charge:
0
Heavy Atom Count:
52
Hydrogen Bond Acceptor Count:
15
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
736.668g/mol
Monoisotopic Mass:
736.233g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
153A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells. | Neurotoxicology and teratology 20150101 |
| Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation. | Peptides 20121001 |
| Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II. | Experimental physiology 20120901 |
| Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors. | Stroke 20120901 |
| Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats. | Hypertension (Dallas, Tex. : 1979) 20120901 |
| Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanism. | Hypertension (Dallas, Tex. : 1979) 20120901 |
| Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells. | Regulatory peptides 20120820 |
| Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells. | Regulatory peptides 20120820 |
| Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway. | Regulatory peptides 20120820 |
| Presence and physiologic function of the renin-angiotensin system in mouse lacrimal gland. | Investigative ophthalmology & visual science 20120813 |
| Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. | Hypertension (Dallas, Tex. : 1979) 20120801 |
| Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells. | Canadian journal of physiology and pharmacology 20120801 |
| Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function. | Psychopharmacology 20120701 |
| AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20120601 |
| Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401 |
| From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists. | Journal of medicinal chemistry 20120308 |
| HIV-associated nephropathy: role of AT2R. | Cellular signalling 20120301 |
| Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. | Hypertension (Dallas, Tex. : 1979) 20120201 |
| Mechanisms of dopamine D(1) and angiotensin type 2 receptor interaction in natriuresis. | Hypertension (Dallas, Tex. : 1979) 20120201 |
| Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory. | Neurobiology of learning and memory 20120101 |
| The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats. | Journal of vascular research 20120101 |
| The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary. | TheScientificWorldJournal 20120101 |
| Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs. | Atherosclerosis 20111201 |
| Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size. | Cytokine 20111201 |
| Cardioplegia and angiotensin II receptor antagonists modulate signal transducers and activators of transcription activation in neonatal rat myocytes. | Artificial organs 20111101 |
| Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. | Clinical science (London, England : 1979) 20111001 |
| Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes. | Neuropeptides 20111001 |
| Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures. | Journal of neurochemistry 20111001 |
| Intracellular angiotensin II activates rat myometrium. | American journal of physiology. Cell physiology 20110901 |
| Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20110901 |
| Activation of central angiotensin type 2 receptors suppresses norepinephrine excretion and blood pressure in conscious rats. | American journal of hypertension 20110601 |
| 20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1. | American journal of physiology. Heart and circulatory physiology 20110401 |
| A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function. | Hypertension (Dallas, Tex. : 1979) 20110301 |
| Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway. | Peptides 20110201 |
| Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes. | Cardiovascular drugs and therapy 20110201 |
| Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension. | Hypertension (Dallas, Tex. : 1979) 20110201 |
| Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro. | Regulatory peptides 20110117 |
| Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. | Brain research 20110112 |
| Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein. | Peptides 20110101 |
| Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20110101 |
| Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat. | American journal of physiology. Heart and circulatory physiology 20110101 |
| Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta. | Vascular pharmacology 20110101 |
| The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201 |
| Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2). | Cellular signalling 20101201 |
| p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201 |
| AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201 |
| Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ. | Clinical and experimental pharmacology & physiology 20101201 |
| Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis. | International journal of cancer 20101115 |
| Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death. | Journal of neuropathology and experimental neurology 20101101 |
| Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway. | Journal of cellular physiology 20101001 |
| Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. | American journal of physiology. Heart and circulatory physiology 20101001 |
| Angiotensin II enhances connecting tubule glomerular feedback. | Hypertension (Dallas, Tex. : 1979) 20101001 |
| [Regeneration of perivascular nerve and role of angiotensin receptors]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100901 |
| Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice. | Arteriosclerosis, thrombosis, and vascular biology 20100801 |
| Neuroprotection against retinal ischemia-reperfusion injury by blocking the angiotensin II type 1 receptor. | Investigative ophthalmology & visual science 20100701 |
| The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts. | Free radical biology & medicine 20100701 |
| Multiple cross talk between angiotensin II, bradykinin, and insulin signaling in the cortical thick ascending limb of rat kidney. | Endocrinology 20100701 |
| Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. | Bioorganic & medicinal chemistry 20100615 |
| Expressions of inducible nitric oxide synthase and cyclooxygenase-2 in gastric ischemia-reperfusion: role of angiotensin II. | The Journal of surgical research 20100601 |
| Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum. | Neuropharmacology 20100601 |
| Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. | Basic research in cardiology 20100501 |
| Angiotensin II-activated protein kinase D mediates acute aldosterone secretion. | Molecular and cellular endocrinology 20100412 |
| Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep. | American journal of physiology. Renal physiology 20100401 |
| Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system. | Behavioural brain research 20100305 |
| Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis. | American journal of physiology. Renal physiology 20100301 |
| Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors. | American journal of physiology. Cell physiology 20100201 |
| Inhibitory effects of angiotensin-(1-7) on the nerve stimulation-induced release of norepinephrine and neuropeptide Y from the mesenteric arterial bed. | American journal of physiology. Heart and circulatory physiology 20100201 |
| Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use. | Hypertension (Dallas, Tex. : 1979) 20100201 |
| Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20100201 |
| Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilation. | Hypertension (Dallas, Tex. : 1979) 20100201 |
| Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats. | British journal of pharmacology 20100201 |
| Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes. | Regulatory peptides 20100108 |
| Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension. | Journal of hypertension 20100101 |
| Molecular mechanisms of the antagonistic action between AT1 and AT2 receptors. | Biochemical and biophysical research communications 20100101 |
| Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. | Hypertension (Dallas, Tex. : 1979) 20100101 |
| [The effect of angiotensin II on phosphoinositide-3 kinase/Akt cascade in cultured fibroblasts derived from patients with hypertrophic scars]. | Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20100101 |
| Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage. | Journal of hypertension 20091201 |
| Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization. | Experimental neurology 20091201 |
| Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells. | Canadian journal of physiology and pharmacology 20091201 |
| Angiotensin II receptors are expressed and functional in human esophageal mucosa. | American journal of physiology. Gastrointestinal and liver physiology 20091101 |
| Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor. | American journal of physiology. Heart and circulatory physiology 20091101 |
| Angiotensin II receptor blockade improves matrix metalloproteinases/tissue inhibitor of matrix metalloproteinase-1 balance and restores fibronectin expression in rat infarcted myocardium. | Biochemical and biophysical research communications 20091023 |
| The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy. | Endocrinology 20090901 |
| Acute modulation of myocardial function by angiotensin 1-7. | Peptides 20090901 |
| Guanylyl cyclase-A inhibits angiotensin II type 2 receptor-mediated pro-hypertrophic signaling in the heart. | Endocrinology 20090801 |
| Angiotensin II type-2 (AT2) receptor antagonism alters cardiovascular responses to static exercise and simultaneously changes glutamate/GABA levels within the ventrolateral medulla. | Neuroscience research 20090801 |
| Conditional expression of type 2 angiotensin II receptor in rat vascular smooth muscle cells reveals the interplay of the angiotensin system in matrix metalloproteinase 2 expression and vascular remodeling. | International journal of molecular medicine 20090701 |
| [Role of angiotensin II and JAK2 signal pathway in transdifferentation of renal tubular cells in mice after acute ischemic followed by reperfusion]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701 |
| Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats. | American journal of physiology. Heart and circulatory physiology 20090301 |
| Regulation of T-cell function by endogenously produced angiotensin II. | American journal of physiology. Regulatory, integrative and comparative physiology 20090201 |
| Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20090201 |
| Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice. | Hypertension (Dallas, Tex. : 1979) 20090201 |
| A peripherally administered, centrally acting angiotensin II AT2 antagonist selectively increases brain AT1 receptors and decreases brain tyrosine hydroxylase transcription, pituitary vasopressin and ACTH. | Brain research 20090123 |
| Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors. | Clinical and experimental pharmacology & physiology 20090101 |
| Role of angiotensin II in the response to endothelin-1 of goat cerebral arteries after ischemia-reperfusion. | Vascular pharmacology 20090101 |
| Role of angiotensin II type 1 receptor on retinal vascular leakage in a rat oxygen-induced retinopathy model. | Ophthalmic research 20090101 |
| Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. | BMC cardiovascular disorders 20090101 |
| The influence of peptides from the angiotensin family on tyrosine kinase activity and cell viability in a human hormone-dependent prostate cancer line. | Endokrynologia Polska 20090101 |
| Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
| Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20081101 |
| Imbalance of angiotensin type 1 receptor and angiotensin II type 2 receptor in the rostral ventrolateral medulla: potential mechanism for sympathetic overactivity in heart failure. | Hypertension (Dallas, Tex. : 1979) 20081001 |
| Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides. | Life sciences 20080912 |
| Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma. | Atherosclerosis 20080901 |
| Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts. | Journal of cardiovascular pharmacology 20080801 |
| Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system. | Endocrinology 20080701 |
| Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
| Intradermal angiotensin II administration attenuates the local cutaneous vasodilator heating response. | American journal of physiology. Heart and circulatory physiology 20080701 |
| Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide. | Hypertension (Dallas, Tex. : 1979) 20080701 |
| Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney. | European journal of pharmacology 20080624 |
| Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye. | Investigative ophthalmology & visual science 20080601 |
| Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension. | Cardiovascular research 20080601 |
| Angiotensin II type 2 receptor stimulation increases the rate of NG108-15 cell migration via actin depolymerization. | Endocrinology 20080601 |
| Angiotensin II receptor blocker inhibits tumour necrosis factor-alpha-induced cell damage in human renal proximal tubular epithelial cells. | Nephrology (Carlton, Vic.) 20080601 |
| Contractility of placental vascular smooth muscle cells in response to stimuli produced by the placenta: roles of ACE vs. non-ACE and AT1 vs. AT2 in placental vessel cells. | Placenta 20080601 |
| Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. | Experimental physiology 20080501 |
| Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring. | Hypertension (Dallas, Tex. : 1979) 20080401 |
| Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells. | American journal of physiology. Renal physiology 20080401 |
| Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone. | Pediatric research 20080401 |
| Analysis of the vasorelaxant action of angiotensin II in the isolated rat renal artery. | Journal of pharmacological sciences 20080301 |
| Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet. | Journal of gastrointestinal and liver diseases : JGLD 20080301 |
| Role of the renin angiotensin system in TNF-alpha and Shiga-toxin-induced tissue factor expression. | Pediatric nephrology (Berlin, Germany) 20080201 |
| Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis. | Hypertension (Dallas, Tex. : 1979) 20080201 |
| Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats. | Hypertension (Dallas, Tex. : 1979) 20080201 |
| Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20080201 |
| Evidence for functional expression of vascular angiotensin II type 2 receptors in patients with insulin resistance. | Diabetes, obesity & metabolism 20080201 |
| Negative inotropic effect of selective AT2 receptor stimulation and its modulation by the endocardial endothelium. | European journal of pharmacology 20080114 |
| Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080101 |
| Improvement of stunned myocardium in dogs with olmesartan, an angiotensin II type 1 receptor antagonist, is independent of type 2 receptors. | Pharmacology 20080101 |
| Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice. | Respiratory research 20080101 |
| Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization. | Neuroendocrinology 20080101 |
| Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries. | Neuroscience 20071212 |
| Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro. | Biochemical and biophysical research communications 20071123 |
| Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes. | Clinical and experimental pharmacology & physiology 20071101 |
| Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway. | Hypertension (Dallas, Tex. : 1979) 20071101 |
| The effect of angiotensin II and IV on ERK1/2 and CREB signalling in cultured rat astroglial cells. | Naunyn-Schmiedeberg's archives of pharmacology 20071101 |
| The role of angiotensin II in the early stages of bovine ovulation. | Reproduction (Cambridge, England) 20071101 |
| [The influence of angiotensin II receptor blockade on the expressions of Col I and TIMP-1 mRNA in cardiac fibroblast of adult rat]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20071101 |
| Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis. | American journal of physiology. Regulatory, integrative and comparative physiology 20071001 |
| Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor. | Endocrine 20071001 |
| Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease. | Journal of cardiovascular pharmacology 20071001 |
| [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. | Zhonghua xin xue guan bing za zhi 20071001 |
| Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway. | Investigative ophthalmology & visual science 20070901 |
| Expression of the local angiotensin II system in gastric cancer may facilitate lymphatic invasion and nodal spread. | Cancer biology & therapy 20070801 |
| Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan. | European journal of pharmacology 20070719 |
| 17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors. | European journal of pharmacology 20070719 |
| Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production. | Pharmacological research 20070701 |
| [Signal transductional mechanism of calpain involved in the regulation of rat hypertrophy myocardium mediated by overloaded pressure]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070701 |
| Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect. | Atherosclerosis 20070601 |
| Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide. | American journal of physiology. Heart and circulatory physiology 20070601 |
| On the mechanism of coronary vasodilation induced by angiotensin-(1-7) in the isolated guinea pig heart. | Basic & clinical pharmacology & toxicology 20070601 |
| Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging. | American journal of physiology. Renal physiology 20070501 |
| Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells. | Endocrinology 20070501 |
| Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain. | Brain research 20070427 |
| Angiotensin II type 2 receptor decreases ischemia reperfusion induced fluid leak. | The Journal of surgical research 20070401 |
| Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1. | Molecular endocrinology (Baltimore, Md.) 20070201 |
| Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor. | American journal of physiology. Heart and circulatory physiology 20070201 |
| The role of angiotensin II in stress urinary incontinence: A rat model. | Neurourology and urodynamics 20070101 |
| Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism. | Hypertension (Dallas, Tex. : 1979) 20070101 |
| [Alteration of signal transduction-associated gene expression in rat cardiac fibroblasts induced by blocking angiotensin II receptors]. | Sheng li xue bao : [Acta physiologica Sinica] 20061225 |
| Translocation of AT1- and AT2-receptors by higher concentrations of angiotensin II in the smooth muscle cells of rat internal anal sphincter. | The Journal of pharmacology and experimental therapeutics 20061201 |
| Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes. | Hypertension (Dallas, Tex. : 1979) 20061201 |
| Regulation of cGMP synthesis in cultured podocytes by vasoactive hormones. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201 |
| Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships. | Journal of medicinal chemistry 20061130 |
| Angiotensin II regulates migration in mouse cultured mesangial cells: evidence for the presence of receptor subtype-specific regulation. | The Journal of endocrinology 20061101 |
| Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE. | American journal of physiology. Regulatory, integrative and comparative physiology 20061001 |
| Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism. | Neuropeptides 20061001 |
| Biphasic actions of angiotensin IV on renal blood flow in the rat. | Regulatory peptides 20060911 |
| Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses. | Peptides 20060901 |
| Angiotensin type 1 and type 2 receptor blockade in chronic allograft nephropathy. | Kidney international 20060901 |
| Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro. | Acta physiologica (Oxford, England) 20060901 |
| AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases. | American journal of physiology. Renal physiology 20060801 |
| Angiotensin II disrupts inhibitory avoidance memory retrieval. | Hormones and behavior 20060801 |
| Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats. | Hypertension (Dallas, Tex. : 1979) 20060601 |
| AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activation. | British journal of pharmacology 20060601 |
| Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones. | The Journal of physiology 20060515 |
| The AT1A receptor 'gain-of-function' mutant N111S/delta329 is both constitutively active and hyperreactive to angiotensin II. | American journal of physiology. Endocrinology and metabolism 20060501 |
| Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance. | Metabolism: clinical and experimental 20060401 |
| Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat. | Hypertension (Dallas, Tex. : 1979) 20060301 |
| Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor. | European journal of pharmacology 20060215 |
| Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. | American journal of physiology. Cell physiology 20060201 |
| Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats. | American journal of physiology. Renal physiology 20060201 |
| Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans. | Diabetologia 20060201 |
| Role of angiotensin II receptor subtypes in porcine basilar artery: functional, radioligand binding, and cell culture studies. | Life sciences 20060125 |
| Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats. | Journal of hypertension 20060101 |
| Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes. | Nephron. Experimental nephrology 20060101 |
| Angiotensin II regulates extraneuronal dopamine uptake in the kidney. | Nephron. Physiology 20060101 |
| Constrictor and dilator effects of angiotensin II on cerebral arterioles. | Stroke 20051201 |
| Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats. | Journal of hypertension 20051201 |
| Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats. | Neuroreport 20051128 |
| Nitric oxide contributes to AT2 but not AT1 angiotensin II receptor-mediated vasodilatation of porcine pial arteries and arterioles. | European journal of pharmacology 20051121 |
| Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets. | Thrombosis and haemostasis 20051101 |
| NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla. | Circulation research 20051014 |
| Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. | Hypertension (Dallas, Tex. : 1979) 20051001 |
| Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null mice. | Circulation 20050913 |
| Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II. | Peptides 20050901 |
| ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells. | Life sciences 20050826 |
| The effect of angiotensin III on protein tyrosine kinase activity in rat pituitary. | Regulatory peptides 20050815 |
| Angiotensin II and interleukin-1 interact to increase generation of dopaminergic neurons from neurospheres of mesencephalic precursors. | Brain research. Developmental brain research 20050808 |
| Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors. | Peptides 20050801 |
| Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy. | Journal of the American Society of Nephrology : JASN 20050801 |
| Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice. | Hypertension (Dallas, Tex. : 1979) 20050801 |
| Does the AT2-receptor mediate anti-atherosclerotic actions? | Journal of hypertension 20050801 |
| Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats. | Journal of hypertension 20050801 |
| Angiotensin II, type 2 receptor is not involved in the angiotensin II-mediated pro-atherogenic process in ApoE-/- mice. | Journal of hypertension 20050801 |
| Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone. | Hypertension (Dallas, Tex. : 1979) 20050801 |
| In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat. | The European journal of neuroscience 20050801 |
| Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture. | Journal of leukocyte biology 20050701 |
| Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism. | Psychopharmacology 20050501 |
| AT2 receptors contribute to acute blood pressure-lowering and vasodilator effects of AT1 receptor antagonism in conscious normotensive but not hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20050501 |
| Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats. | Hypertension (Dallas, Tex. : 1979) 20050501 |
| Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCdelta inhibition. | Brain research. Molecular brain research 20050427 |
| Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists. | Regulatory peptides 20050415 |
| Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus. | American journal of physiology. Regulatory, integrative and comparative physiology 20050401 |
| Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs. | Pediatric pulmonology 20050401 |
| NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II. | Circulation research 20050401 |
| Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance. | Diabetes 20050401 |
| The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas. | Clinical endocrinology 20050401 |
| Diminution of angiotensin II-induced contraction of the abdominal aorta isolated from Watanabe heritable hyperlipidemic rabbits. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20050401 |
| Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats. | Hypertension (Dallas, Tex. : 1979) 20050201 |
| AT(2) receptors mediate tonic renal medullary vasoconstriction in renovascular hypertension. | British journal of pharmacology 20050201 |
| Angiotensin II-dependent induction of AT(2) receptor expression after renal ablation. | American journal of physiology. Renal physiology 20050101 |
| Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats. | Kidney & blood pressure research 20050101 |
| Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. | Hypertension (Dallas, Tex. : 1979) 20050101 |
| Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system. | Journal of hypertension 20050101 |
| Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells. | Antioxidants & redox signaling 20050101 |
| ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression. | Biochemical and biophysical research communications 20041210 |
| Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II. | Circulation research 20041210 |
| Angiotensin II stimulates Pax-2 in rat kidney proximal tubular cells: impact on proliferation and apoptosis. | Kidney international 20041201 |
| Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells. | The Journal of endocrinology 20041201 |
| Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201 |
| Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. | Journal of medicinal chemistry 20041118 |
| Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade. | Journal of molecular and cellular cardiology 20041101 |
| Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway. | The Journal of pharmacology and experimental therapeutics 20041001 |
| A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta. | Naunyn-Schmiedeberg's archives of pharmacology 20041001 |
| Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression. | Brain research. Molecular brain research 20040910 |
| Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat. | Journal of neurochemistry 20040901 |
| Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells. | Acta pharmacologica Sinica 20040901 |
| Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors. | The European journal of neuroscience 20040901 |
| Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor. | Regulatory peptides 20040815 |
| The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis. | Regulatory peptides 20040715 |
| Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB. | Arteriosclerosis, thrombosis, and vascular biology 20040701 |
| Altered effects of angiotensin ii type 1 and type 2 receptor blockers on cardiac norepinephrine release and inotropic responses during cardiac sympathetic nerve stimulation in aorto-caval shunt rats. | Circulation journal : official journal of the Japanese Circulation Society 20040701 |
| AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat. | Molecular and cellular biochemistry 20040701 |
| Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. | Circulation research 20040625 |
| Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist. | Circulation research 20040611 |
| Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding. | Hypertension (Dallas, Tex. : 1979) 20040601 |
| Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor. | Journal of the American Society of Nephrology : JASN 20040601 |
| Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20040601 |
| Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries. | Circulation 20040518 |
| Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors. | Hypertension (Dallas, Tex. : 1979) 20040501 |
| Angiotensin type-1 receptor blockade increases ACE 2 expression in the heart. | Hypertension (Dallas, Tex. : 1979) 20040501 |
| Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice. | Hypertension (Dallas, Tex. : 1979) 20040501 |
| Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats. | Brain research 20040501 |
| Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats. | Regulatory peptides 20040415 |
| First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo. | Journal of medicinal chemistry 20040311 |
| Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells. | Molecular endocrinology (Baltimore, Md.) 20040301 |
| Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301 |
| Dietary salt intake modulates progression of antithymocyte serum nephritis through alteration of glomerular angiotensin II receptor expression. | American journal of physiology. Renal physiology 20040201 |
| Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis. | The international journal of biochemistry & cell biology 20040201 |
| Retinal expression of vascular endothelial growth factor is mediated by angiotensin type 1 and type 2 receptors. | Hypertension (Dallas, Tex. : 1979) 20040201 |
| Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. | Diabetologia 20040201 |
| Different AT1 receptor subtypes at pre- and postjunctional sites: AT1A versus AT1B receptors. | Journal of cardiovascular pharmacology 20040101 |
| Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney. | Nephron. Experimental nephrology 20040101 |
| Increase in systemic blood pressure during intra-arterial PD123319 infusion: evidence for functional expression of angiotensin type 2 receptors in normal volunteers. | Blood pressure 20040101 |
| Importance of the angiotensin type 1 receptor in angiotensin II-induced bronchoconstriction and bronchial hyperresponsiveness in the guinea pig. | Experimental lung research 20040101 |
| Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes. | Molecular and cellular biochemistry 20031201 |
| Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart. | Circulation 20031111 |
| Responses to GABA-A receptor blockade in the hypothalamic PVN are attenuated by local AT1 receptor antagonism. | American journal of physiology. Regulatory, integrative and comparative physiology 20031101 |
| Effects of angiotensin II on nitric oxide generation in growing and resting rat aortic endothelial cells. | Journal of hypertension 20031101 |
| Angiotensin II type 2 receptor inhibits prorenin processing in juxtaglomerular cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20031101 |
| Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice. | Hypertension (Dallas, Tex. : 1979) 20031001 |
| Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. | Circulation 20030923 |
| Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells. | Circulation research 20030905 |
| Patients with steroid refractory acute vascular rejection develop agonistic antibodies targeting angiotensin II type 1 receptor. | Transplantation proceedings 20030901 |
| Effects of angiotensin II on nitric oxide generation in proliferating and quiescent rat coronary microvascular endothelial cells. | Hypertension research : official journal of the Japanese Society of Hypertension 20030901 |
| Disparate roles of AT2 receptors in the renal cortical and medullary circulations of anesthetized rabbits. | Hypertension (Dallas, Tex. : 1979) 20030801 |
| Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade. | British journal of pharmacology 20030801 |
| Angiotensin II and III microinjections into the zona incerta influence drinking behavior. | Brain research 20030711 |
| Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression. | American journal of physiology. Regulatory, integrative and comparative physiology 20030701 |
| Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615 |
| Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats. | The international journal of biochemistry & cell biology 20030601 |
| An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity. | Shock (Augusta, Ga.) 20030601 |
| No involvement of the AT2-receptor in angiotensin II-enhanced sympathetic transmission in vitro. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601 |
| Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601 |
| Angiotensin II AT(1) and AT(2) receptors contribute to maintain basal adrenomedullary norepinephrine synthesis and tyrosine hydroxylase transcription. | Endocrinology 20030501 |
| Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy. | Brain research 20030404 |
| Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20030401 |
| Influence of angiotensin II receptor subtypes of the paraventricular nucleus on the physiological responses induced by angiotensin II injection into the medial septal area. | Arquivos brasileiros de cardiologia 20030401 |
| Angiotensin II-induced release of oxytocin: interaction with norepinephrine and role in lactation. | Regulatory peptides 20030328 |
| The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception. | Regulatory peptides 20030328 |
| ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling. | American journal of physiology. Heart and circulatory physiology 20030301 |
| Role of the angiotensin II system in regulation of ovulation and blood flow in the rat ovary. | Reproduction (Cambridge, England) 20030301 |
| Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR. | Journal of molecular and cellular cardiology 20030301 |
| Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function. | Circulation research 20030221 |
| Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR. | American journal of physiology. Regulatory, integrative and comparative physiology 20030101 |
| Angiotensin II type 2 receptor blockade partially negates antihypertrophic effects of type 1 receptor blockade on pressure-overload rat cardiac hypertrophy. | Hypertension research : official journal of the Japanese Society of Hypertension 20030101 |
| Effect of neutral endopeptidase inhibition on vascular response induced by exogenous angiotensin I in the isolated rat lung. | Polish journal of pharmacology 20030101 |
| Prejunctional AT(1) receptor subtype-dependent modification of neurotransmitter releases in canine isolated splenic arteries. | Autonomic & autacoid pharmacology 20030101 |
| Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis. | Circulation research 20021213 |
| Biphasic regulation of Na+-HCO3- cotransporter by angiotensin II type 1A receptor. | Hypertension (Dallas, Tex. : 1979) 20021101 |
| Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7). | Hypertension (Dallas, Tex. : 1979) 20021101 |
| Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease. | Arteriosclerosis, thrombosis, and vascular biology 20021101 |
| Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Interaction between paraventricular nucleus and septal area in the control of physiological responses induced by angiotensin II. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901 |
| Effect of intranasal administration of CV-11974, a type 1 angiotensin II receptor antagonist, on airway hyperresponsiveness and airway inflammation induced by antigen inhalation in guinea pigs. | International archives of allergy and immunology 20020901 |
| Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20020901 |
| Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells. | Wiener klinische Wochenschrift 20020830 |
| Angiotensin actions on the isolated rat uterus during the estrous cycle: influence of resting membrane potential and uterine morphology. | Pharmacology 20020701 |
| Angiotensin II induces apoptosis in rat glomerular epithelial cells. | American journal of physiology. Renal physiology 20020701 |
| Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury. | Journal of the American Society of Nephrology : JASN 20020701 |
| Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20020701 |
| Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. | Journal of hypertension 20020601 |
| Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways. | Laboratory investigation; a journal of technical methods and pathology 20020601 |
| 125I[Sar(1)Ile(8)] angiotensin II has a different affinity for AT(1) and AT(2) receptor subtypes in ovine tissues. | Regulatory peptides 20020515 |
| Role of angiotensin II and angiotensin II receptors in vascular smooth muscle cell migration in vitro. | Chinese medical journal 20020501 |
| AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats. | Behavioural brain research 20020401 |
| Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II. | American journal of physiology. Lung cellular and molecular physiology 20020401 |
| Influence of estrogen and/or progesterone on isolated ovariectomized rat uterus. Responsiveness to Ang II. | Pharmacology 20020401 |
| Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor. | Brain research. Molecular brain research 20020328 |
| Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles. | Life sciences 20020322 |
| Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles. | Hypertension (Dallas, Tex. : 1979) 20020301 |
| Forearm vasodilator response to angiotensin II in elderly women receiving candesartan: role of AT(2)- receptors. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301 |
| Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB. | American journal of physiology. Heart and circulatory physiology 20020201 |
| The mechanism of angiotensin II binding downregulation by high glucose in primary renal proximal tubule cells. | American journal of physiology. Renal physiology 20020201 |
| Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors. | American journal of physiology. Renal physiology 20020201 |
| Dilatation of cerebral parenchymal vessels mediated by angiotensin type 1 receptor in cats. | Neuroscience letters 20020125 |
| Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor. | Regulatory peptides 20020115 |
| Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors. | Journal of cardiovascular pharmacology 20020101 |
| Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo. | The Journal of pharmacology and experimental therapeutics 20020101 |
| Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats. | The Journal of physiology 20020101 |
| Vasoconstriction is determined by interstitial rather than circulating angiotensin II. | British journal of pharmacology 20020101 |
| Angiotensin II type 2 receptor counter-regulates type 1 receptor in catecholamine synthesis in cultured porcine adrenal medullary chromaffin cells. | Hypertension (Dallas, Tex. : 1979) 20020101 |
| Angiotensin II in cardiac pressure-overload hypertrophy in fetal sheep. | American journal of physiology. Regulatory, integrative and comparative physiology 20011201 |
| AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction. | American journal of physiology. Heart and circulatory physiology 20011201 |
| Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors. | Journal of the American Society of Nephrology : JASN 20011201 |
| Intracellular angiotensin II inhibits heterologous receptor stimulated Ca2+ entry. | Life sciences 20011130 |
| Angiotensin subtype-2 receptor (AT2 ) negatively regulates subtype-1 receptor (AT1 ) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells. | Journal of hypertension 20011101 |
| Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue. | Reproduction (Cambridge, England) 20011101 |
| Corpuscles of Stannius secrete renin or an isorenin that regulates cardiovascular function in freshwater North American eels, Anguilla rostrata LeSueur. | General and comparative endocrinology 20011101 |
| Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats. | Hypertension (Dallas, Tex. : 1979) 20011101 |
| Identification and characterization of functional angiotensin II type 1 receptors on immortalized human fetal aortic vascular smooth muscle cells. | Molecular and cellular endocrinology 20011025 |
| Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice. | Regulatory peptides 20011015 |
| Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells. | Circulation 20011009 |
| Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia. | The Journal of endocrinology 20011001 |
| Role of AT1 and AT2 receptor subtypes in salt-sensitive hypertension induced by sensory nerve degeneration. | Journal of hypertension 20011001 |
| Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis. | British journal of pharmacology 20011001 |
| Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase. | Hypertension (Dallas, Tex. : 1979) 20010901 |
| Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure. | Hypertension (Dallas, Tex. : 1979) 20010901 |
| No effect of angiotensin II AT(2)-receptor antagonist PD 123319 on cerebral blood flow autoregulation. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20010901 |
| Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation. | The Journal of pharmacology and experimental therapeutics 20010801 |
| Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells. | American journal of physiology. Renal physiology 20010801 |
| Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation. | Journal of neurochemistry 20010801 |
| Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP. | Hypertension (Dallas, Tex. : 1979) 20010801 |
| Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction. | Cardiovascular research 20010701 |
| Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells. | Endocrinology 20010701 |
| Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron. | American journal of physiology. Endocrinology and metabolism 20010601 |
| Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt. | American journal of physiology. Regulatory, integrative and comparative physiology 20010601 |
| Coronary hemodynamic and ventricular responses to angiotensin type 1 receptor inhibition in SHR: interaction with angiotensin type 2 receptors. | Hypertension (Dallas, Tex. : 1979) 20010601 |
| Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601 |
| Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells. | European journal of pharmacology 20010518 |
| Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries. | American journal of physiology. Heart and circulatory physiology 20010501 |
| Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors. | The American journal of pathology 20010501 |
| Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons. | Journal of neurophysiology 20010501 |
| Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms. | The Journal of biological chemistry 20010427 |
| Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons. | Regulatory peptides 20010420 |
| Angiotensin receptor in the heart of Bothrops jararaca snake. | European journal of pharmacology 20010406 |
| Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis in the rat. | Synapse (New York, N.Y.) 20010401 |
| Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis. | American journal of physiology. Regulatory, integrative and comparative physiology 20010401 |
| Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia. | American journal of physiology. Regulatory, integrative and comparative physiology 20010401 |
| Intracellular Angiotensin II and cell growth of vascular smooth muscle cells. | British journal of pharmacology 20010401 |
| At receptor inhibition affects the noradrenaline sensitivity in isolated portal vein of normotensive rat. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20010401 |
| Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury. | Hypertension research : official journal of the Japanese Society of Hypertension 20010301 |
| Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II. | Investigative ophthalmology & visual science 20010201 |
| Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor. | British journal of pharmacology 20010201 |
| Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels. | Hypertension (Dallas, Tex. : 1979) 20010201 |
| p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY. | Hypertension (Dallas, Tex. : 1979) 20010201 |
| Regulation of K+ transport in the rat distal colon via angiotensin II subtype receptors and K+ -pathways. | Acta physiologica Scandinavica 20010201 |
| Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning. | Acta physiologica Scandinavica 20010201 |
| Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation. | Circulation research 20010119 |
| Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN). | American journal of physiology. Regulatory, integrative and comparative physiology 20010101 |
| Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice. | American journal of physiology. Renal physiology 20010101 |
| Functional expression of angiotensin II receptors in type-I cells of the rat carotid body. | Pflugers Archiv : European journal of physiology 20010101 |
| Angiotensin II activates nuclear transcription factor-kappaB in aorta of normal rats and in vascular smooth muscle cells of AT1 knockout mice. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101 |
| Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis. | Kidney international 20001201 |
| The involvement of AT(2)-receptor in the antithrombotic effect of losartan in renal hypertensive rats. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20000901 |
| Angiotensin in the nucleus tractus solitarii contributes to neurogenic hypertension caused by chronic nitric oxide synthase inhibition. | Hypertension (Dallas, Tex. : 1979) 20000801 |
| Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 19980901 |
| Angiotensin receptor blockade blunts hyperinsulinemia-induced hypertension in rats. | Hypertension (Dallas, Tex. : 1979) 19980801 |
| Effect of interactions between nitric oxide and angiotensin II on pressure diuresis and natriuresis. | The American journal of physiology 19971101 |
| Molecular mechanism of angiotensin II type I and type II receptors in cardiac hypertrophy of spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 19971001 |
| Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. | Journal of medicinal chemistry 19960202 |
| Regulated expression of angiotensin II (AT2) binding sites in R3T3 cells. | Regulatory peptides 19930319 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.