CAS 136534-70-8 | Piperidine, 4-phenyl-1-(4-phenylbutyl)- | CAS Number 136534-70-8

200,000+ products from a single source!

sales@angenechem.com

Product Categories

Home > Other Building Blocks > 136534-70-8

136534-70-8 | Piperidine, 4-phenyl-1-(4-phenylbutyl)-

CAS No: 136534-70-8 Catalog No: AG00121S MDL No:

Product Description

Catalog Number:

AG00121S

Chemical Name:

Piperidine, 4-phenyl-1-(4-phenylbutyl)-

CAS Number:

136534-70-8

Molecular Formula:

C21H27N

Molecular Weight:

293.4458

IUPAC Name:

4-phenyl-1-(4-phenylbutyl)piperidine

InChI:

InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2

InChI Key:

HQGDPZPNAXRCSA-UHFFFAOYSA-N

SMILES:

c1ccc(cc1)CCCCN1CCC(CC1)c1ccccc1

Properties

Complexity:

280

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

293.214g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

293.454g/mol

Monoisotopic Mass:

293.214g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

3.2A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

5.2

Literature

Title	Journal
Sigma-1 receptor agonists provide neuroprotection against gp120 via a change in bcl-2 expression in mouse neuronal cultures.	Brain research 20120111
The σ 1 receptor agonist 4-PPBP elicits ERK1/2 phosphorylation in primary neurons: a possible mechanism of neuroprotective action.	Neuropharmacology 20101101
Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons.	Experimental neurology 20100101
Cyclic adenosine monophosphate response element-binding protein phosphorylation and neuroprotection by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP).	Anesthesia and analgesia 20090301
Potentiation of nerve growth factor-induced neurite outgrowth by fluvoxamine: role of sigma-1 receptors, IP3 receptors and cellular signaling pathways.	PloS one 20080101
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.	Brain research 20071121
Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2.	Anesthesia and analgesia 20070501
Theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of STAT-1.	Mediators of inflammation 20060101
Potent sigma 1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine provides ischemic neuroprotection without altering dopamine accumulation in vivo in rats.	Anesthesia and analgesia 20030201
Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production.	Stroke 20010701