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13636-18-5 | Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1)
CAS No: 13636-18-5 Catalog No: AG0011T3 MDL No:
Product Description
Catalog Number:
AG0011T3
Chemical Name:
Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1)
CAS Number:
13636-18-5
Molecular Formula:
C23H26ClN
Molecular Weight:
351.9122
IUPAC Name:
3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;hydrochloride
InChI:
InChI=1S/C23H25N.ClH/c1-19(20-11-5-2-6-12-20)24-18-17-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22;/h2-16,19,23-24H,17-18H2,1H3;1H
InChI Key:
NJXWZWXCHBNOOG-UHFFFAOYSA-N
SMILES:
CC(c1ccccc1)NCCC(c1ccccc1)c1ccccc1.Cl
EC Number:
237-121-5
NSC Number:
757826
Properties
Complexity:
303
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
351.175g/mol
Formal Charge:
0
Heavy Atom Count:
25
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
351.918g/mol
Monoisotopic Mass:
351.175g/mol
Rotatable Bond Count:
7
Topological Polar Surface Area:
12A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Real-time 2D separation by LC × differential ion mobility hyphenated to mass spectrometry. | Analytical and bioanalytical chemistry 20120301 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells. | Human & experimental toxicology 20090101 |
| Interaction of antagonists with calmodulin: insights from molecular dynamics simulations. | Journal of medicinal chemistry 20080612 |
| [Role of apoptosis in the kidney after reperfusion]. | Orvosi hetilap 20080217 |
| 2'-hydroxy-fendiline analogues as potent relaxers of isolated arteries. | European journal of pharmacology 20070430 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods. | Journal of molecular graphics & modelling 20060301 |
| Spectrofluorimetric determination of fendiline in tablets. | Die Pharmazie 20051001 |
| 3-Chloro,4-methoxyfendiline is a potent GABA(B) receptor potentiator in rat neocortical slices. | European journal of pharmacology 20050110 |
| Calcium sensing receptors as integrators of multiple metabolic signals. | Cell calcium 20040301 |
| Calcimimetic and calcilytic drugs: just for parathyroid cells? | Cell calcium 20040301 |
| Arylalkylamines are a novel class of positive allosteric modulators at GABA(B) receptors in rat neocortex. | European journal of pharmacology 20020906 |
| The anti-anginal drug fendiline elevates cytosolic Ca(2+) in rabbit corneal epithelial cells. | Life sciences 20020719 |
| Fendiline mobilizes intracellular Ca2+ in Chang liver cells. | Clinical and experimental pharmacology & physiology 20010901 |
| Fendiline, an anti-anginal drug, increases intracellular Ca2+ in PC3 human prostate cancer cells. | Cancer chemotherapy and pharmacology 20010701 |
| Effects of the antianginal drug fendiline on Ca2+ movement in hepatoma cells. | Human & experimental toxicology 20010701 |
| Determination of fendiline and gallopamil by capillary isotachophoresis. | Journal of chromatography. B, Biomedical sciences and applications 20010615 |
| Dual effect of the antianginal drug fendiline on bladder female transitional carcinoma cells: mobilization of intracellular CA2+ and induction of cell death. | Pharmacology 20010501 |
| Fendiline-Induced Ca2+ movement in A10 smooth muscle cells. | The Chinese journal of physiology 20010331 |
| The anti-anginal drug fendiline increases intracellular Ca(2+) levels in MG63 human osteosarcoma cells. | Toxicology letters 20010308 |
| A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies. | Journal of molecular biology 20000331 |
| Crystallization and preliminary diffraction analysis of Ca(2+)-calmodulin-drug and apocalmodulin-drug complexes. | Proteins 19970501 |
| [The relationship between anticonvulsant and anti-anxiety effects of calcium channel blockers]. | Eksperimental'naia i klinicheskaia farmakologiia 19970101 |
| Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta. | The Journal of pharmacology and experimental therapeutics 19920501 |
| Effects of the calmodulin antagonists fendiline and calmidazolium on aggregation, secretion of ATP, and internal calcium in washed human platelets. | Naunyn-Schmiedeberg's archives of pharmacology 19910101 |
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