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13311-84-7 | Propanamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-
CAS No: 13311-84-7 Catalog No: AG00149V MDL No:MFCD00072009
Product Description
Catalog Number:
AG00149V
Chemical Name:
Propanamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-
CAS Number:
13311-84-7
Molecular Formula:
C11H11F3N2O3
Molecular Weight:
276.2118
MDL Number:
MFCD00072009
IUPAC Name:
2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
InChI:
InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChI Key:
MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES:
O=C(C(C)C)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-]
EC Number:
236-341-9
UNII:
76W6J0943E
Properties
Complexity:
352
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
276.072g/mol
Formal Charge:
0
Heavy Atom Count:
19
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
276.215g/mol
Monoisotopic Mass:
276.072g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
74.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.3
Literature
| Title | Journal |
|---|---|
| Endocrine disrupting activities and immunomodulatory effects in lymphoblastoid cell lines of diclofenac, 4-hydroxydiclofenac and paracetamol. | Toxicology letters 20180915 |
| The urinary metabolites of DINCH(®) have an impact on the activities of the human nuclear receptors ERα, ERβ, AR, PPARα and PPARγ. | Toxicology letters 20180501 |
| Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. | Archives of toxicology 20180101 |
| Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. | Reproductive toxicology (Elmsford, N.Y.) 20180101 |
| Differentiating true androgen receptor inhibition from cytotoxicity-mediated reduction of reporter-gene transactivation in-vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20171201 |
| Improved androgen specificity of AR-EcoScreen by CRISPR based glucocorticoid receptor knockout. | Toxicology in vitro : an international journal published in association with BIBRA 20171201 |
| Iminoenamine based novel androgen receptor antagonist exhibited anti-prostate cancer activity in androgen independent prostate cancer cells through inhibition of AKT pathway. | Chemico-biological interactions 20170925 |
| Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR. | Toxicology letters 20170805 |
| Prediction of drug-induced liver injury using keratinocytes. | Journal of applied toxicology : JAT 20170701 |
| The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity. | Toxicology and applied pharmacology 20170615 |
| Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. | Chemical research in toxicology 20170515 |
| Anti-androgen 2-hydroxyflutamide modulates cadherin, catenin and androgen receptor phosphorylation in androgen-sensitive LNCaP and androgen-independent PC3 prostate cancer cell lines acting via PI3K/Akt and MAPK/ERK1/2 pathways. | Toxicology in vitro : an international journal published in association with BIBRA 20170401 |
| Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates. | Archives of toxicology 20170301 |
| Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models. | Toxicological sciences : an official journal of the Society of Toxicology 20170301 |
| Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. | Toxicology and applied pharmacology 20170301 |
| Incorporation of a metabolizing system in biodetection assays for endocrine active substances. | ALTEX 20170101 |
| Downscaling procedures reduce chemical use in androgen receptor reporter gene assay. | The Science of the total environment 20161115 |
| Androgen Receptor Involvement in Rat Amelogenesis: An Additional Way for Endocrine-Disrupting Chemicals to Affect Enamel Synthesis. | Endocrinology 20161101 |
| Manipulation of pre and postnatal androgen environments and anogenital distance in rats. | Toxicology 20160810 |
| High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20160601 |
| Development and pre-validation of an in vitro transactivation assay for detection of (anti)androgenic potential compounds using 22Rv1/MMTV cells. | Reproductive toxicology (Elmsford, N.Y.) 20160401 |
| Hydroxyflutamide affects connexin 43 via the activation of PI3K/Akt-dependent pathway but has no effect on the crosstalk between PI3K/Akt and ERK1/2 pathways at the Raf-1 kinase level in primary rat Sertoli cells. | Toxicology in vitro : an international journal published in association with BIBRA 20160301 |
| The ability of the YAS and AR CALUX assays to detect the additive effects of anti-androgenic fungicide mixtures. | Toxicology letters 20160122 |
| Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. | Immunity & ageing : I & A 20160101 |
| Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach. | Toxicology and applied pharmacology 20151215 |
| The brominated flame retardants TBP-AE and TBP-DBPE antagonize the chicken androgen receptor and act as potential endocrine disrupters in chicken LMH cells. | Toxicology in vitro : an international journal published in association with BIBRA 20151201 |
| Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines. | Environmental science and pollution research international 20151001 |
| Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
| Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish. | Toxicological sciences : an official journal of the Society of Toxicology 20150401 |
| Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish. | Proceedings of the National Academy of Sciences of the United States of America 20150203 |
| Identification of a group of brominated flame retardants as novel androgen receptor antagonists and potential neuronal and endocrine disrupters. | Environment international 20150101 |
| 17β-trenbolone, an anabolic-androgenic steroid as well as an environmental hormone, contributes to neurodegeneration. | Toxicology and applied pharmacology 20150101 |
| Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats. | Toxicology 20141003 |
| Species-specific considerations in using the fish embryo test as an alternative to identify endocrine disruption. | Aquatic toxicology (Amsterdam, Netherlands) 20141001 |
| Rapid fluorescent detection of (anti)androgens with spiggin-gfp medaka. | Environmental science & technology 20140916 |
| Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips. | Toxicology in vitro : an international journal published in association with BIBRA 20140801 |
| Identification of gene expression changes in postnatal rat foreskin after in utero anti-androgen exposure. | Reproductive toxicology (Elmsford, N.Y.) 20140801 |
| Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury. | Toxicology letters 20140703 |
| Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement. | American journal of physiology. Heart and circulatory physiology 20140601 |
| Testosterone ameliorates streptozotocin-induced memory impairment in male rats. | Acta pharmacologica Sinica 20140601 |
| Environmental (anti-)androgenic chemicals affect germinal vesicle breakdown (GVBD) of Xenopus laevis oocytes in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20140401 |
| A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
| Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
| Flutamide-induced cytotoxicity and oxidative stress in an in vitro rat hepatocyte system. | Oxidative medicine and cellular longevity 20140101 |
| FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1. | Chemico-biological interactions 20130905 |
| Androgen deprivation from pre-puberty to peripuberty interferes in proteins expression in pubertal and adult rat epididymis. | Reproductive toxicology (Elmsford, N.Y.) 20130701 |
| HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved. | Archives of toxicology 20130601 |
| Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and Its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips. | Toxicological sciences : an official journal of the Society of Toxicology 20130301 |
| Effects of the natural endocrine disruptor equol on the pituitary function in adult male rats. | Toxicology 20130208 |
| Androgen deprivation by flutamide modulates uPAR, MMP-9 expressions, lipid profile, and oxidative stress: amelioration by daidzein. | Molecular and cellular biochemistry 20130201 |
| Ligand-independent androgen receptor antagonism caused by the newly developed pesticide pyrifluquinazon (PFQ). | Reproductive toxicology (Elmsford, N.Y.) 20130101 |
| Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts. | Journal of periodontal research 20121201 |
| Elevated level of 17β-estradiol is associated with overexpression of FSHR, CYP19A1, and CTNNB1 genes in porcine ovarian follicles after prenatal and neonatal flutamide exposure. | Theriogenology 20121201 |
| Biopsy Gleason score and the duration of testosterone suppression among men treated with external beam radiation and 6 months of combined androgen blockade. | BJU international 20121101 |
| Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells. | The Journal of pharmacology and experimental therapeutics 20121101 |
| The influence of reproductive hormones on the torpor patterns of the marsupial Sminthopsis macroura: bet-hedging in an unpredictable environment. | General and comparative endocrinology 20121101 |
| Hepatotoxicity with flutamide. | Fertility and sterility 20121101 |
| In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer. | Molecular endocrinology (Baltimore, Md.) 20121101 |
| Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury. | Journal of applied toxicology : JAT 20121001 |
| Anti-androgenic effects of S-40542, a novel non-steroidal selective androgen receptor modulator (SARM) for the treatment of benign prostatic hyperplasia. | The Prostate 20121001 |
| Steroid derivatives as pure antagonists of the androgen receptor. | The Journal of steroid biochemistry and molecular biology 20121001 |
| Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue. | The Journal of clinical endocrinology and metabolism 20121001 |
| Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females. | Fertility and sterility 20121001 |
| Regression of the mammary branch of the genitofemoral nerve may be necessary for testicular descent in rats. | The Journal of urology 20121001 |
| Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway. | American journal of physiology. Endocrinology and metabolism 20120915 |
| Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer. | Urologic oncology 20120901 |
| Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782. | Cancer 20120901 |
| Stage-specific effects of androgens and estradiol-17beta on the development of late primary and early secondary ovarian follicles of coho salmon (Oncorhynchus kisutch) in vitro. | Biology of reproduction 20120901 |
| Cellular actions of testosterone in vascular cells: mechanism independent of aromatization to estradiol. | Steroids 20120901 |
| PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs. | International journal of pharmaceutics 20120820 |
| Flutamide, an androgen receptor antagonist, improves heatstroke outcomes in mice. | European journal of pharmacology 20120805 |
| Administration of flutamide alters sperm ultrastructure, sperm plasma membrane integrity and its stability, and sperm mitochondrial oxidative capability in the boar: in vivo and in vitro approach. | Reproduction in domestic animals = Zuchthygiene 20120801 |
| Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA. | International journal of radiation oncology, biology, physics 20120801 |
| Addition of radiotherapy to long-term androgen deprivation in locally advanced prostate cancer: an open randomised phase 3 trial. | European urology 20120801 |
| The anxiolytic effect of testosterone in the rat is mediated via the androgen receptor. | Pharmacology, biochemistry, and behavior 20120801 |
| Regulation of LKB1 expression by sex hormones in adipocytes. | International journal of obesity (2005) 20120701 |
| Outcome predictors of radical prostatectomy followed by adjuvant androgen deprivation in patients with clinical high risk prostate cancer and pT3 surgical margin positive disease. | The Journal of urology 20120701 |
| Antitumor agents 290. Design, synthesis, and biological evaluation of new LNCaP and PC-3 cytotoxic curcumin analogs conjugated with anti-androgens. | Bioorganic & medicinal chemistry 20120701 |
| Are expression and localization of tight and adherens junction proteins in testes of adult boar affected by foetal and neonatal exposure to flutamide? | International journal of andrology 20120601 |
| Exposure of neonatal rats to anti-androgens induces penile mal-developments and infertility comparable to those induced by oestrogens. | International journal of andrology 20120601 |
| Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty. | Reproductive toxicology (Elmsford, N.Y.) 20120601 |
| Flutamide increases aldosterone levels in gonadectomized male but not female Wistar rats. | American journal of hypertension 20120601 |
| A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity. | Drug metabolism and disposition: the biological fate of chemicals 20120601 |
| Prostate cancer in elderly Croatian men: 5-HT genetic polymorphisms and the influence of androgen deprivation therapy on osteopenia--a pilot study. | Genetic testing and molecular biomarkers 20120601 |
| Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver. | Drug metabolism and disposition: the biological fate of chemicals 20120601 |
| Developmental programming: prenatal and postnatal contribution of androgens and insulin in the reprogramming of estradiol positive feedback disruptions in prenatal testosterone-treated sheep. | Endocrinology 20120601 |
| Inulin-based hydrogel for oral delivery of flutamide: preparation, characterization, and in vivo release studies. | Macromolecular bioscience 20120601 |
| The influence of testosterone suppression and recovery on sexual function in men with prostate cancer: observations from a prospective study in men undergoing intermittent androgen suppression. | The Journal of urology 20120601 |
| Fluorinated and pegylated polyaspartamide derivatives to increase solubility and efficacy of Flutamide. | Journal of drug targeting 20120601 |
| Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways. | Hypertension (Dallas, Tex. : 1979) 20120601 |
| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
| Long-term dynamics of bone mineral density during intermittent androgen deprivation for men with nonmetastatic, hormone-sensitive prostate cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120520 |
| Insulin resistance in women with hirsutism. | Archives of medical science : AMS 20120509 |
| Activation of PKR/eIF2α signaling cascade is associated with dihydrotestosterone-induced cell cycle arrest and apoptosis in human liver cells. | Journal of cellular biochemistry 20120501 |
| Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20120501 |
| Prenatal and neonatal flutamide administration increases proliferation and reduces apoptosis in large antral follicles of adult pigs. | Animal reproduction science 20120501 |
| Testosterone up-regulates seladin-1 expression by iAR and PI3-K/Akt signaling pathway in C6 cells. | Neuroscience letters 20120411 |
| Androgens affect myogenesis in vitro and increase local IGF-1 expression. | Medicine and science in sports and exercise 20120401 |
| Prenatal and neonatal exposure to flutamide affects function of Leydig cells in adult boar. | Domestic animal endocrinology 20120401 |
| Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. | Drug metabolism and disposition: the biological fate of chemicals 20120401 |
| Endosulfan and flutamide, alone and in combination, target ovarian growth in juvenile catfish, Clarias batrachus. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120401 |
| Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins. | Cell biology and toxicology 20120401 |
| Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway. | The Journal of endocrinology 20120401 |
| Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus. | Aquatic toxicology (Amsterdam, Netherlands) 20120401 |
| Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor. | The FEBS journal 20120401 |
| Immunomodulatory effects of testosterone evaluated in all-trans retinoic acid differentiated HL-60 cells, granulocytes, and monocytes. | International immunopharmacology 20120401 |
| The vasodilatory effect of testosterone on renal afferent arterioles. | Gender medicine 20120401 |
| Dehydroepiandrosterone reduces preadipocyte proliferation via androgen receptor. | American journal of physiology. Endocrinology and metabolism 20120315 |
| Association of prolactin-induced protein with preputial development of hypospadias. | BJU international 20120301 |
| Mechanistic study on liver tumor promoting effects of flutamide in rats. | Archives of toxicology 20120301 |
| Evaluation of drugs with specific organ toxicities in organ-specific cell lines. | Toxicological sciences : an official journal of the Society of Toxicology 20120301 |
| Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway. | The Journal of endocrinology 20120301 |
| Regional differences in the vasorelaxing effects of testosterone and its 5-reduced metabolites in the canine vasculature. | Vascular pharmacology 20120301 |
| Ten-year follow-up of neoadjuvant therapy with goserelin acetate and flutamide before radical prostatectomy for clinical T3 and T4 prostate cancer: update on Southwest Oncology Group Study 9109. | Urology 20120301 |
| Nilutamide. | Acta crystallographica. Section E, Structure reports online 20120301 |
| Prostate cancer with neuroendocrine differentiation--case report. | Journal of medicine and life 20120222 |
| Effect of methanol extract of Basella alba L. (Basellaceae) on the fecundity and testosterone level in male rats exposed to flutamide in utero. | Andrologia 20120201 |
| The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis. | Pharmacological research 20120201 |
| Effect of gonadal steroid hormones on formalin-induced temporomandibular joint inflammation. | European journal of pain (London, England) 20120201 |
| Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line. | Journal of cellular physiology 20120101 |
| Surgical castration in hormone-refractory metastatic prostate cancer patients can be an alternative for medical castration. | Advances in urology 20120101 |
| Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats. | Molecular and cellular biochemistry 20120101 |
| The role of the androgen receptor in anabolic androgenic steroid-induced aggressive behavior in C57BL/6J and Tfm mice. | Hormones and behavior 20120101 |
| Androgen signaling in decidualizing human endometrial stromal cells enhances resistance to oxidative stress. | Fertility and sterility 20120101 |
| Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: effects of nandrolone decanoate and catechin. | Steroids 20120101 |
| Management of high-risk localized prostate cancer. | Advances in urology 20120101 |
| Juvenile angiofibroma: evolution of management. | International journal of pediatrics 20120101 |
| Alterations in vasomotor systems and mechanics of resistance-sized mesenteric arteries from SHR and WKY male rats following in vivo testosterone manipulation. | Biology of sex differences 20120101 |
| Dehydroepiandrosterone (DHEA) inhibition of monocyte binding by vascular endothelium is associated with sialylation of neural cell adhesion molecule. | Reproductive sciences (Thousand Oaks, Calif.) 20120101 |
| The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases. | Advances in urology 20120101 |
| Clinical Efficacy of TroVax in the Treatment of Progressive Castration-resistant Prostate Cancer. | Clinical Medicine Insights. Oncology 20120101 |
| Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat. | PloS one 20120101 |
| Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20120101 |
| Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. | Drug design, development and therapy 20120101 |
| Androgenic suppression combined with radiotherapy for the treatment of prostate adenocarcinoma: a systematic review. | BMC cancer 20120101 |
| Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. | Chemistry Central journal 20120101 |
| Fetal radiation exposure induces testicular cancer in genetically susceptible mice. | PloS one 20120101 |
| The role of adjuvant hormonal treatment after surgery for localized high-risk prostate cancer: results of a matched multiinstitutional analysis. | Advances in urology 20120101 |
| Androgen receptor drives cellular senescence. | PloS one 20120101 |
| Cardiac arrest due to lymphocytic colitis: a case report. | Journal of medical case reports 20120101 |
| Sex differences in primary hypertension. | Biology of sex differences 20120101 |
| Prenatal exposure to antiandrogen flutamide affects androgen receptor (AR) expression in postnatal ovarian development in pig. | Folia biologica 20120101 |
| Post-translational modifications of nuclear receptors and human disease. | Nuclear receptor signaling 20120101 |
| Androgen receptor-beta mRNA levels in different tissues in breeding and post-breeding male and female sticklebacks, Gasterosteus aculeatus. | Reproductive biology and endocrinology : RB&E 20120101 |
| Redefining hormone sensitive disease in advanced prostate cancer. | Advances in urology 20120101 |
| MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1. | PloS one 20120101 |
| Low lipoprotein(a) concentration is associated with cancer and all-cause deaths: a population-based cohort study (the JMS cohort study). | PloS one 20120101 |
| Effects of trauma-hemorrhage and IL-6 deficiency on splenic immune function in a murine trauma model. | Mediators of inflammation 20120101 |
| Does 2-hydroxyflutamide inhibit apoptosis in porcine granulosa cells? - An in vitro study. | The Journal of reproduction and development 20120101 |
| Castration-resistant prostate cancer: mechanisms, targets, and treatment. | Prostate cancer 20120101 |
| The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer. | Advances in urology 20120101 |
| Role of endogenous testosterone in TNF-induced myocardial injury in males. | International journal of clinical and experimental medicine 20120101 |
| Double-blinded, vehicle-controlled proof of concept study to investigate the recurrence of inflammatory and noninflammatory acne lesions using tretinoin gel (microsphere) 0.04% in male patients after oral isotretinoin use. | Dermatology research and practice 20120101 |
| Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos. | PloS one 20120101 |
| The current role of androgen deprivation in patients undergoing dose-escalated external beam radiation therapy for clinically localized prostate cancer. | Prostate cancer 20120101 |
| McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia. | Orphanet journal of rare diseases 20120101 |
| Estrogenic regulation of the GnRH neuron. | Frontiers in endocrinology 20120101 |
| Flutamide treatment induces anxiolytic-like behavior in adult castrated rats. | Pharmacological reports : PR 20120101 |
| Emerging targeted therapies for castration-resistant prostate cancer. | Frontiers in endocrinology 20120101 |
| Radiation, inflammation, and immune responses in cancer. | Frontiers in oncology 20120101 |
| The emerging role of human esterases. | Drug metabolism and pharmacokinetics 20120101 |
| Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors. | PloS one 20120101 |
| Treatment of female pattern hair loss. | Skinmed 20120101 |
| Postnatal exposure to low-dose decabromodiphenyl ether adversely affects mouse testes by increasing thyrosine phosphorylation level of cortactin. | The Journal of toxicological sciences 20120101 |
| Physiological effects of androgens on human vascular endothelial and smooth muscle cells in culture. | Steroids 20111220 |
| Bioassay-directed identification of novel antiandrogenic compounds in bile of fish exposed to wastewater effluents. | Environmental science & technology 20111215 |
| Differential expression of connexin 43 in adult pig testes during normal spermatogenic cycle and after flutamide treatment. | Reproduction in domestic animals = Zuchthygiene 20111201 |
| Clinical efficacy of primary combined androgen blockade for Japanese men with clinically localized prostate cancer unsuitable for local definitive treatment: a single institution experience. | International journal of clinical oncology 20111201 |
| Relative importance of prenatal and postnatal androgen action in determining growth of the penis and anogenital distance in the rat before, during and after puberty. | International journal of andrology 20111201 |
| Androgen receptor coregulators NOCR1, TIF2, and ARA70 may account for the hydroxyflutamide insensitivity of prostate cancer cells. | Irish journal of medical science 20111201 |
| Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone. | American journal of physiology. Gastrointestinal and liver physiology 20111201 |
| A novel steroidal antiandrogen targeting wild type and mutant androgen receptors. | Biochemical pharmacology 20111201 |
| Developmental programming: gestational testosterone treatment alters fetal ovarian gene expression. | Endocrinology 20111201 |
| Adjuvant therapy with flutamide for presurgical volume reduction in juvenile nasopharyngeal angiofibroma. | Head & neck 20111201 |
| The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent. | Journal of pediatric surgery 20111201 |
| Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum. | Journal of pediatric surgery 20111201 |
| Testosterone depletion or blockade in male rats protects against trauma hemorrhagic shock-induced distant organ injury by limiting gut injury and subsequent production of biologically active mesenteric lymph. | The Journal of trauma 20111201 |
| [Monotherapy versus combined androgen blockade for advanced/metastatic prostate cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Cooperative antitumor effect of endothelial-monocyte activating polypeptide II and flutamide on human prostate cancer xenografts. | Experimental oncology 20111201 |
| Fatty acid-binding protein-4 plasma levels are associated to metabolic abnormalities and response to therapy in girls and young women with androgen excess. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111101 |
| Significance of pretreatment cardiovascular morbidity as a risk factor during treatment with parenteral oestrogen or combined androgen deprivation of 915 patients with metastasized prostate cancer: evaluation of cardiovascular events in a randomized trial. | Scandinavian journal of urology and nephrology 20111101 |
| Androgen deprivation therapy through bilateral orchiectomy: increased metabolic risks. | Asian journal of andrology 20111101 |
| Treatment of androgen excess in adolescent girls: ethinylestradiol-cyproteroneacetate versus low-dose pioglitazone-flutamide-metformin. | The Journal of clinical endocrinology and metabolism 20111101 |
| Functionally similar acoustic signals in the corncrake (Crex crex) transmit information about different states of the sender during aggressive interactions. | Hormones and behavior 20111101 |
| Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells. | Anticancer research 20111101 |
| Retrospective, observational study on the effects and tolerability of flutamide in a large population of patients with acne and seborrhea over a 15-year period. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111001 |
| Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation. | Biology of reproduction 20111001 |
| Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae. | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20111001 |
| Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland. | Endocrinology 20111001 |
| Cremaster muscle myogenesis in the tip of the rat gubernaculum supports active gubernacular elongation during inguinoscrotal testicular descent. | The Journal of urology 20111001 |
| Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells. | Anticancer research 20111001 |
| Disruption of CD38 gene enhances cardiac functions by elevating serum testosterone in the male null mice. | Life sciences 20110926 |
| Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening. | Journal of medicinal chemistry 20110922 |
| Immunohistochemical studies on the proliferative marker Ki-67 and estrogen receptor alpha (ERα) in the uterus of neonatal and immature pigs following exposure to flutamide. | Acta histochemica 20110901 |
| A randomized trial (Irish clinical oncology research group 97-01) comparing short versus protracted neoadjuvant hormonal therapy before radiotherapy for localized prostate cancer. | International journal of radiation oncology, biology, physics 20110901 |
| Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats. | Archives of toxicology 20110901 |
| Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial. | Scandinavian journal of urology and nephrology 20110901 |
| Short-term exposure to a treated sewage effluent alters reproductive behaviour in the three-spined stickleback (Gasterosteus aculeatus). | Aquatic toxicology (Amsterdam, Netherlands) 20110901 |
| Non-migratory stonechats show seasonal changes in the hormonal regulation of non-seasonal territorial aggression. | Hormones and behavior 20110901 |
| [The regulation of T3 on maldeveloped gonocyte (Go) and expression of NCAM in flutamide-induced cryptorchidism rat]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110901 |
| Recent adverse trends in semen quality and testis cancer incidence among Finnish men. | International journal of andrology 20110801 |
| Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate. | Andrologia 20110801 |
| Development of a highly sensitive cytotoxicity assay system for CYP3A4-mediated metabolic activation. | Drug metabolism and disposition: the biological fate of chemicals 20110801 |
| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. | Environmental health perspectives 20110801 |
| Aldol derivatives of Thioxoimidazolidinones as potential anti-prostate cancer agents. | European journal of medicinal chemistry 20110801 |
| Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay. | Regulatory toxicology and pharmacology : RTP 20110801 |
| Female tail wagging enhances sexual performance in male goats. | Hormones and behavior 20110801 |
| Polymer swelling, drug mobilization and drug recrystallization in hydrating solid dispersion tablets studied by multinuclear NMR microimaging and spectroscopy. | Molecular pharmaceutics 20110801 |
| Structural changes and immunohistochemical localisation of epidermal growth factor receptor in the true vocal fold of female albino rats administered anabolic, androgenic steroids, and effects of anti-androgen therapy. | The Journal of laryngology and otology 20110801 |
| The effects of testosterone on craniosynostotic calvarial cells: a test of the gene/environmental model of craniofacial anomalies. | Orthodontics & craniofacial research 20110801 |
| Androgen and estrogen receptor expression in the spinal segments of the genitofemoral nerve during testicular descent. | Journal of pediatric surgery 20110801 |
| Pharmacogenetics of glucocorticoid replacement could optimize the treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. | Clinics (Sao Paulo, Brazil) 20110801 |
| An assessment of androgenic/anti-androgenic effects of GH transgenic carp by Hershberger assay. | Biomedical and environmental sciences : BES 20110801 |
| [Spontaneous complete remission in two patients with chronic lymphocytic leukemia]. | Medicina clinica 20110723 |
| Radiotherapy and short-term androgen deprivation for localized prostate cancer. | The New England journal of medicine 20110714 |
| Lyophilization monophase solution technique for preparation of amorphous flutamide dispersions. | Drug development and industrial pharmacy 20110701 |
| Resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectra of copper(II)-Flutamide system with anionic surfactants and its analytical application. | Journal of fluorescence 20110701 |
| Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
| Identification strategy for unknown pollutants using high-resolution mass spectrometry: androgen-disrupting compounds identified through effect-directed analysis. | Analytical and bioanalytical chemistry 20110701 |
| A molecular and phenotypic integrative approach to identify a no-effect dose level for antiandrogen-induced testicular toxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20110701 |
| Effects of testosterone on renal function in salt-loaded rats. | The American journal of the medical sciences 20110701 |
| Testosterone modulation of cardiac β-adrenergic signals in a rat model of heart failure. | General and comparative endocrinology 20110701 |
| A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids. | Journal of dermatological science 20110701 |
| Sperm storage in the female reproductive tract of Scotophilus heathii: role of androgen. | Molecular reproduction and development 20110701 |
| The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production. | Reproductive toxicology (Elmsford, N.Y.) 20110701 |
| Efficacy of alternative antiandrogen therapy for prostate cancer that relapsed after initial maximum androgen blockade. | Korean journal of urology 20110701 |
| Biopolymeric microparticles combined with lyophilized monophase dispersions for controlled flutamide release. | International journal of pharmaceutics 20110615 |
| The expression of FSH receptor (FSHR) in the neonatal porcine ovary and its regulation by flutamide. | Reproduction in domestic animals = Zuchthygiene 20110601 |
| The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator. | Integrative cancer therapies 20110601 |
| DDT and malaria prevention: addressing the paradox. | Environmental health perspectives 20110601 |
| Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. | Environmental health perspectives 20110601 |
| Blockade of androgen receptor in the medial amygdala inhibits noncontact erections in male rats. | Physiology & behavior 20110601 |
| Androgen receptors in the posterior bed nucleus of the stria terminalis increase neuropeptide expression and the stress-induced activation of the paraventricular nucleus of the hypothalamus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601 |
| Testosterone relaxes abdominal aorta in male Sprague-Dawley rats by opening potassium (K(+)) channel and blockade of calcium (Ca(2+)) channel. | Pathophysiology : the official journal of the International Society for Pathophysiology 20110601 |
| Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage. | The Prostate 20110601 |
| [Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer : a single center experience]. | Hinyokika kiyo. Acta urologica Japonica 20110601 |
| Clinical Characteristics of Microscopic Colitis in Korea: Prospective Multicenter Study by KASID. | Gut and liver 20110601 |
| Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial. | International journal of radiation oncology, biology, physics 20110501 |
| CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay. | Drug metabolism and disposition: the biological fate of chemicals 20110501 |
| In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20110501 |
| Two panels of steroid receptor luciferase reporter cell lines for compound profiling. | Combinatorial chemistry & high throughput screening 20110501 |
| Prenatal programming by testosterone of hypothalamic metabolic control neurones in the ewe. | Journal of neuroendocrinology 20110501 |
| Short-term neoadjuvant androgen deprivation and radiotherapy for locally advanced prostate cancer: 10-year data from the TROG 96.01 randomised trial. | The Lancet. Oncology 20110501 |
| Mandibular and femoral growth alteration after sex hormone disruption in growing mice. | Orthodontics & craniofacial research 20110501 |
| Treatment of female pattern hair loss with the androgen receptor antagonist flutamide. | The Australasian journal of dermatology 20110501 |
| Drug safety is a barrier to the discovery and development of new androgen receptor antagonists. | The Prostate 20110401 |
| Many putative endocrine disruptors inhibit prostaglandin synthesis. | Environmental health perspectives 20110401 |
| Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures. | Journal of neuroscience research 20110401 |
| Flutamide for androgen excess: low dose is best. | Journal of pediatric and adolescent gynecology 20110401 |
| Lyophilized flutamide dispersions with polyols and amino acids: preparation and in vitro evaluation. | Drug development and industrial pharmacy 20110401 |
| Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. | The Annals of pharmacotherapy 20110401 |
| Testosterone dependent androgen receptor stabilization and activation of cell proliferation in primary human myometrial microvascular endothelial cells. | Fertility and sterility 20110315 |
| Divergent effects of ethinylestradiol-drospirenone and flutamide-metformin on follistatin in adolescents and women with hyperinsulinemic androgen excess. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110301 |
| Serum testosterone level to predict the efficacy of sequential use of antiandrogens as second-line treatment following androgen deprivation monotherapy in patients with castration-resistant prostate cancer. | Japanese journal of clinical oncology 20110301 |
| The mitogenic effect of testosterone and 17β-estradiol on airway smooth muscle cells. | Steroids 20110301 |
| Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery. | Steroids 20110301 |
| Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells. | International journal of oncology 20110301 |
| Castration-resistant prostate cancer: targeted therapies and individualized treatment. | The oncologist 20110301 |
| QSAR models for anti-androgenic effect--a preliminary study. | SAR and QSAR in environmental research 20110301 |
| Current treatment strategies for castration-resistant prostate cancer. | Korean journal of urology 20110301 |
| [Establishment of a rat model of flutamide-induced cryptorchidism with remaining gonocytes]. | Zhonghua nan ke xue = National journal of andrology 20110301 |
| Saudi Oncology Society clinical management guidelines for prostate cancer. | Urology annals 20110301 |
| A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol. | British journal of cancer 20110215 |
| Postnatal blockade of androgen receptors or aromatase impair the expression of stress hypothalamic-pituitary-adrenal axis habituation in adult male rats. | Psychoneuroendocrinology 20110201 |
| Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species. | Biotechnology letters 20110201 |
| The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males. | General and comparative endocrinology 20110201 |
| Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations. | Chemico-biological interactions 20110201 |
| Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP. | Cancer science 20110201 |
| Testosterone is involved in mediating the effects of prenatal stress in male guinea pig offspring. | The Journal of physiology 20110201 |
| Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer. | The American journal of pathology 20110201 |
| [Hormone therapy of locally advanced cancer of the prostate validated by several randomized trials]. | Bulletin du cancer 20110201 |
| Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads. | Aquatic toxicology (Amsterdam, Netherlands) 20110125 |
| Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies. | Journal of medicinal chemistry 20110113 |
| Connexin 43 gene expression in male and female gonads of porcine offspring following in utero exposure to an anti-androgen, flutamide. | Acta histochemica 20110101 |
| Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats. | Hormones and behavior 20110101 |
| Altered expression and localization of estrogen receptors alpha and beta in the testes of a cryptorchid rat model. | Urology 20110101 |
| Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor. | The Biochemical journal 20110101 |
| Copulatory efficiency and fertility in male rats exposed perinatally to flutamide. | Reproductive toxicology (Elmsford, N.Y.) 20110101 |
| Prenatal and neonatal exposure to the antiandrogen flutamide alters connexin 43 gene expression in adult porcine ovary. | Domestic animal endocrinology 20110101 |
| Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures. | Domestic animal endocrinology 20110101 |
| Combined androgen blockade for prostate cancer: review of efficacy, safety and cost-effectiveness. | Cancer science 20110101 |
| Immunomodulation in polytrauma and polymicrobial sepsis - where do we stand? | Recent patents on inflammation & allergy drug discovery 20110101 |
| The American Diabetes Association's 57th annual advanced postgraduate course: diabetes risk, vitamin D, polycystic ovary syndrome, and obstructive sleep apnea. | Diabetes care 20110101 |
| Prognostic factors for failure after prostatectomy. | Journal of Cancer 20110101 |
| Acute and fulminant hepatitis induced by flutamide: case series report and review of the literature. | Annals of hepatology 20110101 |
| Experimental trauma models: an update. | Journal of biomedicine & biotechnology 20110101 |
| Hormone replacement therapy in morphine-induced hypogonadic male chronic pain patients. | Reproductive biology and endocrinology : RB&E 20110101 |
| Treatment options for polycystic ovary syndrome. | International journal of women's health 20110101 |
| Morphological and functional alterations in adult boar epididymis: Effects of prenatal and postnatal administration of flutamide. | Acta veterinaria Scandinavica 20110101 |
| Neoadjuvant hormonal therapy preceding radical prostatectomy for clinically localized prostate cancer: early postoperative complications and biochemical recurrence. | Korean journal of urology 20110101 |
| Enhanced proinflammatory cytokine response to bacterial lipopolysaccharide in the adult male rat after either neonatal or prepubertal ablation of biological testosterone activity. | Neuroimmunomodulation 20110101 |
| Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer. | Breast cancer research : BCR 20110101 |
| Sex hormones modulate salbutamol-elicited long-term relaxation in isolated bovine tracheal strips. | Pharmacology 20110101 |
| MDM2 antagonists boost antitumor effect of androgen withdrawal: implications for therapy of prostate cancer. | Molecular cancer 20110101 |
| IL-6 serum levels and production is related to an altered immune response in polycystic ovary syndrome girls with insulin resistance. | Mediators of inflammation 20110101 |
| Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival. | PloS one 20110101 |
| Duration of androgen deprivation therapy with maximum androgen blockade for localized prostate cancer. | BMC urology 20110101 |
| Testosterone increases: sodium reabsorption, blood pressure, and renal pathology in female spontaneously hypertensive rats on a high sodium diet. | Advances in pharmacological sciences 20110101 |
| Design and evaluation of self-nanoemulsifying drug delivery system of flutamide. | Journal of young pharmacists : JYP 20110101 |
| Effect of 2-hydroxypropyl-β-cyclodextrin on solubility of sparingly soluble drug derivatives of anthranilic acid. | International journal of molecular sciences 20110101 |
| Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression. | PloS one 20110101 |
| Sipuleucel-T for therapy of asymptomatic or minimally symptomatic, castrate-refractory prostate cancer: an update and perspective among other treatments. | OncoTargets and therapy 20110101 |
| Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. | Reproductive biology and endocrinology : RB&E 20110101 |
| Positive HER-2 protein expression in circulating prostate cells and micro-metastasis, resistant to androgen blockage but not diethylstilbestrol. | Indian journal of urology : IJU : journal of the Urological Society of India 20110101 |
| Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy: a case report. | Journal of medical case reports 20110101 |
| Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines. | PloS one 20110101 |
| Flutamide versus a cyproterone acetate-ethinyl estradiol combination in moderate acne: a pilot randomized clinical trial. | Clinical, cosmetic and investigational dermatology 20110101 |
| Six-month gonadotropin releasing hormone (GnRH) agonist depots provide efficacy, safety, convenience, and comfort. | Cancer management and research 20110101 |
| The Hirsute woman: challenges in evaluation and management. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
| Murine polyomavirus virus-like particles carrying full-length human PSA protect BALB/c mice from outgrowth of a PSA expressing tumor. | PloS one 20110101 |
| Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer. | Journal of biomedical science 20110101 |
| Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report. | Journal of medical case reports 20110101 |
| State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS). | International journal of pediatric endocrinology 20110101 |
| ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract. | PloS one 20110101 |
| Dephosphorylated NSSR1 is induced by androgen in mouse epididymis and phosphorylated NSSR1 is increased during sperm maturation. | PloS one 20110101 |
| Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies. | Frontiers in pharmacology 20110101 |
| Mechanism of salutary effects of astringinin on rodent hepatic injury following trauma-hemorrhage: Akt-dependent hemeoxygenase-1 signaling pathways. | PloS one 20110101 |
| Prevalence of microscopic colitis in patients with chronic diarrhea in Egypt: a single-center study. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
| Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. | PloS one 20110101 |
| Metabolic complications and increased cardiovascular risks as a result of androgen deprivation therapy in men with prostate cancer. | Prostate cancer 20110101 |
| New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer. | Prostate cancer 20110101 |
| Adipokines and sexual hormones associated with the components of the metabolic syndrome in pharmacologically untreated subjects: data from the brisighella heart study. | International journal of endocrinology 20110101 |
| Expression profiling of CYP1B1 in oral squamous cell carcinoma: counterintuitive downregulation in tumors. | PloS one 20110101 |
| Effect of Turkish propolis extracts on proteome of prostate cancer cell line. | Proteome science 20110101 |
| Novel therapeutic strategies for malignant salivary gland tumors: lessons learned from breast cancer. | International journal of otolaryngology 20110101 |
| [Effects of cytokine-like polypeptide EMAP II and flutamide on the testosterone-stimulated prostate of castrated rats]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101 |
| Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence. | Journal of carcinogenesis 20110101 |
| Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. | PloS one 20110101 |
| Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer. | Drug, healthcare and patient safety 20110101 |
| Hormones and prostate carcinogenesis: Androgens and estrogens. | Journal of carcinogenesis 20110101 |
| XMRV Discovery and Prostate Cancer-Related Research. | Advances in virology 20110101 |
| Molecular targets for radiation oncology in prostate cancer. | Frontiers in oncology 20110101 |
| A role for the androgen metabolite, 5alpha androstane 3beta, 17beta diol (3β-diol) in the regulation of the hypothalamo-pituitary-adrenal axis. | Frontiers in endocrinology 20110101 |
| Using bisphenol-a to study the onset of polycystic ovarian syndrome. | Frontiers in endocrinology 20110101 |
| Role of neuroactive steroids in the peripheral nervous system. | Frontiers in endocrinology 20110101 |
| PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction. | Frontiers in endocrinology 20110101 |
| Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects. | European journal of histochemistry : EJH 20101221 |
| Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure. | Brain research 20101217 |
| Low-dose pioglitazone, flutamide, metformin plus an estro-progestagen for non-obese young women with polycystic ovary syndrome: increasing efficacy and persistent safety over 30 months. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20101201 |
| Inhibition of androgen receptor and Cdc25A phosphatase as a combination targeted therapy in molecular apocrine breast cancer. | Cancer letters 20101201 |
| Effect of androgen deprivation therapy on the expression of prostate cancer biomarkers MSMB and MSMB-binding protein CRISP3. | Prostate cancer and prostatic diseases 20101201 |
| Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy. | Neuro-degenerative diseases 20101201 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Successful drug development despite adverse preclinical findings part 2: examples. | Journal of toxicologic pathology 20101201 |
| Alterations in the developing testis transcriptome following embryonic vinclozolin exposure. | Reproductive toxicology (Elmsford, N.Y.) 20101101 |
| Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth. | Molecular pharmacology 20101101 |
| Alternative antiandrogen therapy in patients with castration-resistant prostate cancer: a single-center experience. | International journal of urology : official journal of the Japanese Urological Association 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Testosterone-down-regulated Akt pathway during cardiac ischemia/reperfusion: a mechanism involving BAD, Bcl-2 and FOXO3a. | The Journal of surgical research 20101101 |
| Adrenocorticotropic hormone is involved in regulation of androgen synthesis in men receiving androgen deprivation therapy for localized prostate cancer. | The Journal of urology 20101101 |
| Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro. | Chemosphere 20101101 |
| Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment. | Cell death & disease 20101101 |
| Testosterone exacerbates neuronal damage following cardiac arrest and cardiopulmonary resuscitation in mouse. | Brain research 20101021 |
| The lack of estrogen and excess luteinizing hormone are responsible for the female ArKO mouse phenotype. | Molecular and cellular endocrinology 20101007 |
| Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity. | International journal of experimental pathology 20101001 |
| Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men. | American journal of physiology. Endocrinology and metabolism 20101001 |
| Serum prostate-specific antigen levels reflect the androgen milieu in patients with localized prostate cancer receiving androgen deprivation therapy: Tumor malignant potential and androgen milieu. | The Prostate 20100915 |
| PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line. | Cancer chemotherapy and pharmacology 20100901 |
| Mate calling behavior of male South African clawed frogs (Xenopus laevis) is suppressed by the antiandrogenic endocrine disrupting compound flutamide. | General and comparative endocrinology 20100901 |
| Aromatase mRNA expression in the brain of adult Xenopus laevis exposed to Lambro river water and endocrine disrupting compounds. | General and comparative endocrinology 20100901 |
| Arylacetamide deacetylase is a determinant enzyme for the difference in hydrolase activities of phenacetin and acetaminophen. | Drug metabolism and disposition: the biological fate of chemicals 20100901 |
| The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors. | The Journal of pharmacology and experimental therapeutics 20100901 |
| Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model. | Aquatic toxicology (Amsterdam, Netherlands) 20100901 |
| Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice. | The Journal of antimicrobial chemotherapy 20100901 |
| Hormonal suppression restores fertility in irradiated mice from both endogenous and donor-derived stem spermatogonia. | Toxicological sciences : an official journal of the Society of Toxicology 20100901 |
| Value of combined androgen blockade in the neoadjuvant treatment of localized prostate cancer: the jury must remain out. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100901 |
| Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer: a retrospective clinical experience from a Chinese medical centre. | Asian journal of andrology 20100901 |
| Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice. | Neuroscience 20100825 |
| Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats. | Neuroscience 20100811 |
| Assessment of a recombinant androgen receptor binding assay: initial steps towards validation. | Reproductive toxicology (Elmsford, N.Y.) 20100801 |
| Short-term dynamic culture of rat testicular fragments as a model to assess effects on steroidogenesis--potential use and limitations. | Reproductive toxicology (Elmsford, N.Y.) 20100801 |
| Flutamide inhibits nifedipine- and interleukin-1 beta-induced collagen overproduction in gingival fibroblasts. | Journal of periodontal research 20100801 |
| Androgen receptor blockade in the posterodorsal medial amygdala impairs sexual odor preference in male rats. | Hormones and behavior 20100801 |
| Optimization and prevalidation of the in vitro AR CALUX method to test androgenic and antiandrogenic activity of compounds. | Reproductive toxicology (Elmsford, N.Y.) 20100801 |
| Castration induces changes in the cation-dependent mannose-6-phosphate receptor in rat epididymis: possible implications in secretion of lysosomal enzymes. | Journal of cellular biochemistry 20100801 |
| Androgens regulate adenylate cyclase activity and intracellular calcium in stromal cells derived from human prostate. | The Prostate 20100801 |
| Therapy: Low-dose flutamide for hirsutism: into the limelight, at last. | Nature reviews. Endocrinology 20100801 |
| Words of wisdom. Re: Does oral antiandrogen use before leuteinizing hormone-releasing therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare? Oh WK, Landrum MB, Lamont EB, et al. Urology 2010;75:642-7. | European urology 20100801 |
| Radiation with or without 6 months of androgen suppression therapy in intermediate- and high-risk clinically localized prostate cancer: a postrandomization analysis by risk group. | International journal of radiation oncology, biology, physics 20100715 |
| Intramolecular charge transfer effects on flutamide drug. | Journal of fluorescence 20100701 |
| A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species. | Aquatic toxicology (Amsterdam, Netherlands) 20100701 |
| Retrospective observational study on the effects and tolerability of flutamide in a large population of patients with various kinds of hirsutism over a 15-year period. | European journal of endocrinology 20100701 |
| Dysregulation of leptin and testosterone production and their receptor expression in the human placenta with gestational diabetes mellitus. | Placenta 20100701 |
| Mitogen-activated protein kinases pathway is involved in physiological testosterone-induced tissue factor pathway inhibitor expression in endothelial cells. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100701 |
| Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro. | Revista espanola de cardiologia 20100701 |
| Effects and mechanisms of progestogens and androgens in ictal activity. | Epilepsia 20100701 |
| Embryonic expression of the cysteine rich protein 61 (CYR61) gene: A candidate for the development of human epispadias. | Birth defects research. Part A, Clinical and molecular teratology 20100701 |
| Specific in vitro toxicity of crude and refined petroleum products: II. Estrogen (alpha and beta) and androgen receptor-mediated responses in yeast assays. | Environmental toxicology and chemistry 20100701 |
| Effects of pre- and postnatal exposure to flutamide on connexin 43 expression in testes and ovaries of prepubertal pigs. | European journal of histochemistry : EJH 20100614 |
| Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs. | Reproduction in domestic animals = Zuchthygiene 20100601 |
| Management of acne vulgaris: an evidence-based update. | Clinical and experimental dermatology 20100601 |
| Blockade of androgen or estrogen receptors reduces nandrolone's ability to modulate acute reward-related neurochemical effects of amphetamine in rat brain. | Pharmacology, biochemistry, and behavior 20100601 |
| Prenatal exposure to vinclozolin disrupts selective aspects of the gonadotrophin-releasing hormone neuronal system of the rabbit. | Journal of neuroendocrinology 20100601 |
| Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat. | Endocrinology 20100601 |
| A selective androgen receptor modulator enhances male-directed sexual preference, proceptive behavior, and lordosis behavior in sexually experienced, but not sexually naive, female rats. | Endocrinology 20100601 |
| Spermatogenesis after 1-stage fowler-stephens orchiopexy in experimental cryptorchid rat model. | The Journal of urology 20100601 |
| Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601 |
| Determination of 2-hydroxyflutamide in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS): application to a bioequivalence study on Chinese volunteers. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601 |
| Androgens and spermatogenesis: lessons from transgenic mouse models. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20100527 |
| Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene. | Experimental cell research 20100515 |
| Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden. | The Lancet. Oncology 20100511 |
| OECD validation of phase-3 Hershberger assay using the stimulated weanling male rat in Korea. | Journal of applied toxicology : JAT 20100501 |
| Correlates of trabecular and cortical volumetric bone mineral density of the radius and tibia in older men: the Osteoporotic Fractures in Men Study. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100501 |
| A mouse model of androgenetic alopecia. | Endocrinology 20100501 |
| Is the 'comb over' dying? A mouse model for male pattern baldness (androgenic alopecia). | Endocrinology 20100501 |
| Effects of flutamide therapy on craniofacial growth and development in a model of craniosynostosis. | The Journal of craniofacial surgery 20100501 |
| [Membrane testosterone receptors in cultured vascular smooth muscle cells]. | Zhonghua nan ke xue = National journal of andrology 20100501 |
| Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) gene: cell-specific expression and transcriptional regulation by androgen in transgenic mouse testis. | Journal of cellular biochemistry 20100415 |
| An in vitro drug-induced hepatotoxicity screening system using CYP3A4-expressing and gamma-glutamylcysteine synthetase knockdown cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| Androgen action in the masculinization programming window and development of male reproductive organs. | International journal of andrology 20100401 |
| Mixture effects of endocrine disrupting compounds in vitro. | International journal of andrology 20100401 |
| The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice. | Reproduction (Cambridge, England) 20100401 |
| Adrenal androgen levels as predictors of outcome in castration-resistant prostate cancer patients treated with combined androgen blockade using flutamide as a second-line anti-androgen. | International journal of urology : official journal of the Japanese Urological Association 20100401 |
| Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay. | Bioorganic & medicinal chemistry letters 20100401 |
| Dioxin-induced changes in epididymal sperm count and spermatogenesis. | Environmental health perspectives 20100401 |
| Microbial metabolism. Part 11. Metabolites of flutamide. | Chemical & pharmaceutical bulletin 20100401 |
| Morphology of the cockerel's comb after androgen administration. | British poultry science 20100401 |
| Synthesis and biodistribution of [99mTc]-N-[4-nitro-3-trifluoromethyl-phenyl] cyclopentadienyltricarbonyltechnetium carboxamide, a nonsteroidal antiandrogen flutamide derivative. | Metallomics : integrated biometal science 20100401 |
| Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification. | The Journal of biological chemistry 20100305 |
| Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones. | Reproduction (Cambridge, England) 20100301 |
| The effects of beta-blockers on endothelial nitric oxide synthase immunoreactivity in the rat corpus cavernosum. | Urology 20100301 |
| Cryptic regulation of vasotocin neuronal activity but not anatomy by sex steroids and social stimuli in opportunistic desert finches. | Brain, behavior and evolution 20100301 |
| [Hormonal antiandrogens in acne treatment]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100301 |
| 'Click' labeling strategy for M(CO)(3) (M = Re, (99m)Tc) prostate cancer targeted flutamide agents. | Dalton transactions (Cambridge, England : 2003) 20100227 |
| Study of the impact of the T877A mutation on ligand-induced helix-12 positioning of the androgen receptor resulted in design and synthesis of novel antiandrogens. | Proteins 20100215 |
| Antiandrogen withdrawal syndrome and alternative antiandrogen therapy associated with the W741C mutant androgen receptor in a novel prostate cancer xenograft. | The Prostate 20100215 |
| Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H. | The Journal of biological chemistry 20100212 |
| C/EBPalpha redirects androgen receptor signaling through a unique bimodal interaction. | Oncogene 20100204 |
| Metastasis of genitourinary tumors to the head and neck region. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100201 |
| Critical androgen-sensitive periods of rat penis and clitoris development. | International journal of andrology 20100201 |
| Up-regulation of circadian clock gene Period 2 in the prostate mesenchymal cells during flutamide-induced apoptosis. | Molecular and cellular biochemistry 20100201 |
| Bone metabolic disorder in patients with prostate cancer receiving androgen deprivation therapy (ADT): impact of ADT on the growth hormone/insulin-like growth factor-1/parathyroid hormone axis. | The Prostate 20100201 |
| Androgenic regulation of ventral epithelial bud number and pattern in mouse urogenital sinus. | Developmental dynamics : an official publication of the American Association of Anatomists 20100201 |
| Lyophilization monophase solution technique for improvement of the physicochemical properties of an anticancer drug, flutamide. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100201 |
| Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells. | Stem cells (Dayton, Ohio) 20100201 |
| Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells. | International journal of oncology 20100201 |
| Anti-androgen treatments. | Annales d'endocrinologie 20100201 |
| Hidden in plain sight: the mammary line in males may be the missing link regulating inguinoscrotal testicular descent. | Journal of pediatric surgery 20100201 |
| The aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD) reduces disinhibitory behavior in intact adult male rats treated with a high dose of testosterone. | Behavioural brain research 20100120 |
| Acute 19-nortestosterone transiently suppresses hippocampal MAPK pathway and the phosphorylation of the NMDA receptor. | Molecular and cellular endocrinology 20100115 |
| Prostate stem cell antigen enhancer and uroplakin II promoter based bladder cancer targeted tissue-specific vector. | Urologic oncology 20100101 |
| Is biochemical response more important than duration of neoadjuvant hormone therapy before radiotherapy for clinically localized prostate cancer? An analysis of the 3- versus 8-month randomized trial. | International journal of radiation oncology, biology, physics 20100101 |
| Long-term follow-up of 3-month neoadjuvant hormone therapy before radical prostatectomy in a randomized trial. | BJU international 20100101 |
| Changes in gene expression in somatic cells of rat testes resulting from hormonal modulation and radiation-induced germ cell depletion. | Biology of reproduction 20100101 |
| The role of androgen receptors in regulating territorial aggression in male song sparrows. | Hormones and behavior 20100101 |
| Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors. | Reproduction (Cambridge, England) 20100101 |
| Does the cranial suspensory ligament have a role in cryptorchidism? | Cells, tissues, organs 20100101 |
| Gene expression profile of androgen modulated genes in the murine fetal developing lung. | Reproductive biology and endocrinology : RB&E 20100101 |
| Hormonal therapy for acne: why not as first line therapy? facts and controversies. | Clinics in dermatology 20100101 |
| Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor. | Journal of biomedical science 20100101 |
| Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems. | PloS one 20100101 |
| Growth and reproductive outcomes in congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
| Age-dependent role of steroids in the regulation of growth of the hen follicular wall. | Reproductive biology and endocrinology : RB&E 20100101 |
| A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899. | Journal of translational medicine 20100101 |
| Lymphocytic colitis presenting as difficult diarrhoea in an African woman: a case report and review of the literature. | Journal of medical case reports 20100101 |
| Exploring the antiperoxidative potential of morin on cyclophosphamide and flutamide-induced lipid peroxidation and changes in cholesterol profile in rabbit model. | Acta poloniae pharmaceutica 20100101 |
| An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. | International journal of pediatric endocrinology 20100101 |
| Testosterone depletion by castration may protect mice from heat-induced multiple organ damage and lethality. | Journal of biomedicine & biotechnology 20100101 |
| The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model. | Biology direct 20100101 |
| Hirsutism: evaluation and treatment. | Indian journal of dermatology 20100101 |
| Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats. | Journal of ovarian research 20100101 |
| WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary. | PloS one 20100101 |
| Maximal androgen blockade for advanced prostate cancer. | Indian journal of urology : IJU : journal of the Urological Society of India 20100101 |
| The changes of cortactin p80/85 isoform profiles and tyrosine phosphorylation status during spermatogenesis in the mouse testis. | Journal of andrology 20100101 |
| Hormonal therapy of prostate cancer. | Progress in brain research 20100101 |
| 3alpha-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats. | Frontiers in aging neuroscience 20100101 |
| Androgen excess produces systemic oxidative stress and predisposes to beta-cell failure in female mice. | PloS one 20100101 |
| Management of the adult with congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
| Update on options for treatment of metastatic castration-resistant prostate cancer. | OncoTargets and therapy 20100101 |
| Alternative strategies for the treatment of classical congenital adrenal hyperplasia: pitfalls and promises. | International journal of pediatric endocrinology 20100101 |
| Nonclassic congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
| Is there an optimal management for localized prostate cancer? | Clinical interventions in aging 20100101 |
| Integrating GHS into the Ghrelin System. | International journal of peptides 20100101 |
| Endocrine disruptors and Leydig cell function. | Journal of biomedicine & biotechnology 20100101 |
| Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats. | Journal of toxicology and environmental health. Part A 20100101 |
| Bypass mechanisms of the androgen receptor pathway in therapy-resistant prostate cancer cell models. | PloS one 20100101 |
| Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: meta-analysis of randomized trials. | BMC cancer 20100101 |
| Testosterone and cholesterol vasodilation of rat aorta involves L-type calcium channel inhibition. | Advances in pharmacological sciences 20100101 |
| Effectiveness of long-term (twelve months) nonsurgical weight loss interventions for obese women with polycystic ovary syndrome: a systematic review. | International journal of women's health 20100101 |
| Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing. | PloS one 20100101 |
| Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells. | Proteome science 20100101 |
| Endocrinology of hirsutism. | International journal of trichology 20100101 |
| Evaluation of degarelix in the management of prostate cancer. | Cancer management and research 20100101 |
| Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art. | Cancer management and research 20100101 |
| Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide. | Asian Pacific journal of cancer prevention : APJCP 20100101 |
| Effect of Buddleia flavonoids drug-containing plasma on the expression of STAT1 phosphoprotein in lacrimal gland epithelial cells in vitro. | International journal of ophthalmology 20100101 |
| Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. | Journal of medicinal chemistry 20091210 |
| Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice. | Biology of reproduction 20091201 |
| Comparison of in vitro hormone activities of selected phthalates using reporter gene assays. | Toxicology letters 20091201 |
| Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins. | Drug metabolism and disposition: the biological fate of chemicals 20091201 |
| Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta. | Endocrinology 20091201 |
| The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development. | Journal of pediatric surgery 20091201 |
| Gynecomastia: An ADR due to drug interaction. | Indian journal of pharmacology 20091201 |
| [Activity induced by androsterone and hemisuccinate of androsterone on perfusion pressure and vascular resistance]. | Biomedica : revista del Instituto Nacional de Salud 20091201 |
| Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. | Journal of medicinal chemistry 20091126 |
| Relevance of an opioid, noscapine in reducing cystogeneses in rat experimental model of polycystic ovary syndrome. | Journal of endocrinological investigation 20091101 |
| A novel androgen-dependent prostate cancer xenograft model derived from skin metastasis of a Japanese patient. | The Prostate 20091101 |
| Prostate cancer survivorship: prevention and treatment of the adverse effects of androgen deprivation therapy. | Journal of general internal medicine 20091101 |
| Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta. | Epilepsy & behavior : E&B 20091101 |
| Basic exploratory research versus guideline-compliant studies used for hazard evaluation and risk assessment: bisphenol A as a case study. | Environmental health perspectives 20091101 |
| Anogenital distance from birth to 2 years: a population study. | Environmental health perspectives 20091101 |
| Metabolomics in drug intolerance. | Current drug metabolism 20091101 |
| Phase II trial of short-term neoadjuvant docetaxel and complete androgen blockade in high-risk prostate cancer. | British journal of cancer 20091020 |
| Neuroprotective effects of testosterone upon cardiac sympathetic function in rats with induced heart failure. | European journal of pharmacology 20091001 |
| Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism. | The FEBS journal 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Sex steroids are necessary in the second postnatal week for the expression of male alloparental behavior in prairie voles (Microtus ochragaster). | Behavioral neuroscience 20091001 |
| Testosterone inhibits the activity of peroxisome proliferator-activated receptor gamma in a transcriptional transaction assay. | Die Pharmazie 20091001 |
| Androgen-mediated apoptosis of kidney tubule cells: role of c-Jun amino terminal kinase. | Biochemical and biophysical research communications 20090925 |
| Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat. | Toxicology letters 20090910 |
| Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells. | Blood 20090910 |
| Low-dose pioglitazone and low-dose flutamide added to metformin and oestro-progestagens for hyperinsulinaemic women with androgen excess: add-on benefits disclosed by a randomized double-placebo study over 24 months. | Clinical endocrinology 20090901 |
| Genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with Hypofractionated External beam radiotherapy for localized prostate cancer: an analysis to determine the correlation between dose-volume histogram parameters in HDR brachytherapy and severity of toxicity. | International journal of radiation oncology, biology, physics 20090901 |
| Long-term effects of intermittent androgen suppression on testosterone recovery and bone mineral density: results of a 33-month observational study. | BJU international 20090901 |
| Radiation dose predicts for biochemical control in intermediate-risk prostate cancer patients treated with low-dose-rate brachytherapy. | International journal of radiation oncology, biology, physics 20090901 |
| Interval to testosterone recovery after hormonal therapy for prostate cancer and risk of death. | International journal of radiation oncology, biology, physics 20090901 |
| Effects of estrogen and androgen deprivation on the progression of non-alcoholic steatohepatitis (NASH) in male Sprague-Dawley rats. | Hepatology research : the official journal of the Japan Society of Hepatology 20090901 |
| Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20090901 |
| The prostate growth stimulation by progesterone is due to androgenic products and progesterone receptor-mediated mechanisms. | Die Pharmazie 20090901 |
| Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. | Journal of immunological methods 20090831 |
| Evaluation of the rodent Hershberger bioassay on intact juvenile males--testing of coded chemicals and supplementary biochemical investigations. | Toxicology 20090803 |
| Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up. | BJU international 20090801 |
| Differential effects of flutamide and di-(2-ethylhexyl) phthalate on male reproductive organs in a rat model. | The Journal of reproduction and development 20090801 |
| Dose-dependent effects of androgens on outcome after focal cerebral ischemia in adult male mice. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090801 |
| Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice. | Hormones and behavior 20090801 |
| Endocrine-disrupting equivalents in industrial effluents discharged into Yangtze River. | Ecotoxicology (London, England) 20090801 |
| Both endogenous and exogenous testosterone decrease myocardial STAT3 activation and SOCS3 expression after acute ischemia and reperfusion. | Surgery 20090801 |
| Calcitonin gene-related peptide is a survival factor, inhibiting apoptosis in neonatal rat gubernaculum in vitro. | Journal of pediatric surgery 20090801 |
| Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
| N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer. | Neoplasia (New York, N.Y.) 20090801 |
| Drug-induced liver disease: an 8-year study of patients from one gastroenterological department. | Journal of digestive diseases 20090801 |
| Pharmacological options for treatment of hyperandrogenic disorders. | Mini reviews in medicinal chemistry 20090801 |
| Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. | Toxicology and applied pharmacology 20090715 |
| Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis. | Drug metabolism and disposition: the biological fate of chemicals 20090701 |
| Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones. | Journal of cellular biochemistry 20090701 |
| Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis. | Analytical and bioanalytical chemistry 20090701 |
| Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms. | Environmental health perspectives 20090701 |
| Hepatotoxicity during low-dose flutamide treatment for hirsutism. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090701 |
| Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors. | ACS chemical biology 20090619 |
| Id-1 expression in androgen-dependent prostate cancer is negatively regulated by androgen through androgen receptor. | Cancer letters 20090618 |
| Duration of androgen suppression in the treatment of prostate cancer. | The New England journal of medicine 20090611 |
| Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. | Cancer chemotherapy and pharmacology 20090601 |
| Recognizing false biochemical failure calls after radiation with or without neo-adjuvant androgen deprivation for prostate cancer. | International journal of radiation oncology, biology, physics 20090601 |
| Growth differentiation factor 9 promotes rat preantral follicle growth by up-regulating follicular androgen biosynthesis. | Endocrinology 20090601 |
| Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations. | Toxicology and applied pharmacology 20090601 |
| Modulation of ovarian structure and abdominal obesity in curcumin- and flutamide-treated aging FSH-R haploinsufficient mice. | Reproductive sciences (Thousand Oaks, Calif.) 20090601 |
| Androgen receptors in coeliac ganglion in late pregnant rat. | Steroids 20090601 |
| Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening. | PLoS computational biology 20090601 |
| Detection of the anti-androgenic effect of endocrine disrupting environmental contaminants using in vivo and in vitro assays in the three-spined stickleback. | Aquatic toxicology (Amsterdam, Netherlands) 20090517 |
| Establishment of a novel immortalized human prostatic epithelial cell line stably expressing androgen receptor and its application for the functional screening of androgen receptor modulators. | Biochemical and biophysical research communications 20090515 |
| Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy. | Cancer research 20090515 |
| Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells. | Molecular and cellular endocrinology 20090506 |
| New insights into the role of androgens in wolffian duct stabilization in male and female rodents. | Endocrinology 20090501 |
| OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals. | Journal of applied toxicology : JAT 20090501 |
| Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas). | Journal of proteome research 20090501 |
| Standard and molecular NOAELs for rat testicular toxicity induced by flutamide. | Toxicological sciences : an official journal of the Society of Toxicology 20090501 |
| Suppression of mutant androgen receptors by flutamide. | International journal of urology : official journal of the Japanese Urological Association 20090501 |
| Regulation of ryanodine receptor-mediated Ca(2+) release in vas deferens smooth muscle cells. | Journal of pharmacological sciences 20090501 |
| Statistical modeling suggests that antiandrogens in effluents from wastewater treatment works contribute to widespread sexual disruption in fish living in English rivers. | Environmental health perspectives 20090501 |
| Long-term safety and tolerability of flutamide for the treatment of hirsutism. | Fertility and sterility 20090401 |
| Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that encompasses most stages of folliculogenesis. | Biology of reproduction 20090401 |
| Quality of life in patients with locally advanced prostate cancer given endocrine treatment with or without radiotherapy: 4-year follow-up of SPCG-7/SFUO-3, an open-label, randomised, phase III trial. | The Lancet. Oncology 20090401 |
| Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro. | Environmental health perspectives 20090401 |
| Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary. | Environmental science & technology 20090401 |
| [Clinical usefulness of chlormadinone acetate as an alternative antiandrogen therapy for prostate cancer relapse after combined androgen blockade therapy]. | Hinyokika kiyo. Acta urologica Japonica 20090401 |
| The risk of hepatotoxicity during long-term and low-dose flutamide treatment in hirsutism. | Archives of gynecology and obstetrics 20090301 |
| Cognitive and mood changes in men undergoing intermittent combined androgen blockade for non-metastatic prostate cancer. | Psycho-oncology 20090301 |
| Age-dependent effects of testosterone in experimental stroke. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090301 |
| Hair loss in women. | Seminars in cutaneous medicine and surgery 20090301 |
| The role of androgen receptor mutations in prostate cancer progression. | Current genomics 20090301 |
| Toxicogenomic biomarkers for liver toxicity. | Journal of toxicologic pathology 20090301 |
| Potential surrogate endpoints for prostate cancer survival: analysis of a phase III randomized trial. | Journal of the National Cancer Institute 20090218 |
| N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1). | Bioorganic & medicinal chemistry letters 20090215 |
| Final report of multicenter Canadian Phase III randomized trial of 3 versus 8 months of neoadjuvant androgen deprivation therapy before conventional-dose radiotherapy for clinically localized prostate cancer. | International journal of radiation oncology, biology, physics 20090201 |
| Dihydrotestosterone stimulates cerebrovascular inflammation through NFkappaB, modulating contractile function. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090201 |
| Twenty-four-month postradiation prostate biopsies are strongly predictive of 7-year disease-free survival: results from a Canadian randomized trial. | Cancer 20090201 |
| Androgen-induced human breast cancer cell proliferation is mediated by discrete mechanisms in estrogen receptor-alpha-positive and -negative breast cancer cells. | The Journal of steroid biochemistry and molecular biology 20090201 |
| Addressing bone loss in the cancer survivor. | Oncology (Williston Park, N.Y.) 20090201 |
| Endocrine treatment, with or without radiotherapy, in locally advanced prostate cancer (SPCG-7/SFUO-3): an open randomised phase III trial. | Lancet (London, England) 20090124 |
| Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer. | British journal of cancer 20090113 |
| Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists. | Prostate cancer and prostatic diseases 20090101 |
| Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis. | Endocrinology 20090101 |
| Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity. | Drug metabolism and disposition: the biological fate of chemicals 20090101 |
| Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. | American journal of physiology. Cell physiology 20090101 |
| Neoadjuvant hormonal deprivation for patients undergoing radical prostatectomy. | Asian journal of andrology 20090101 |
| Synthesis and characterization of nonsteroidal-linked M(CO)(3)+ (M = 99mTc, Re) compounds based on the androgen receptor targeting molecule flutamide. | Bioconjugate chemistry 20090101 |
| Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes. | Journal of andrology 20090101 |
| Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production. | Environmental health perspectives 20090101 |
| Androgen receptor modulation does not affect longitudinal growth of cultured fetal rat metatarsal bones. | Hormone research 20090101 |
| Androgen deprivation modulates the inflammatory response induced by irradiation. | BMC cancer 20090101 |
| A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism. | Journal of endocrinological investigation 20090101 |
| Low-dose flutamide for women with androgen excess: anti-androgenic efficacy and hepatic safety. | Journal of endocrinological investigation 20090101 |
| Long-term follow-up after triple treatment of prostate cancer stage pT3. | Scandinavian journal of urology and nephrology 20090101 |
| The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression. | Reproductive biology and endocrinology : RB&E 20090101 |
| PCOS. | BMJ clinical evidence 20090101 |
| Obsessive-compulsive disorder and related disorders: a comprehensive survey. | Annals of general psychiatry 20090101 |
| Uterine and placental expression of TRPV6 gene is regulated via progesterone receptor- or estrogen receptor-mediated pathways during pregnancy in rodents. | Reproductive biology and endocrinology : RB&E 20090101 |
| Role of maximum androgen blockade in advanced prostate cancer. | Indian journal of urology : IJU : journal of the Urological Society of India 20090101 |
| Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial. | Trials 20090101 |
| The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms. | Health and quality of life outcomes 20090101 |
| Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation. | Molecular cancer 20090101 |
| Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior. | Frontiers in behavioral neuroscience 20090101 |
| Oocyte-granulosa-theca cell interactions during preantral follicular development. | Journal of ovarian research 20090101 |
| Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects? | BMC cancer 20090101 |
| Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. | Journal of translational medicine 20090101 |
| Small-cell prostate carcinoma: A retrospective analysis of five newly reported cases. | Indian journal of urology : IJU : journal of the Urological Society of India 20090101 |
| Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. | BMC medical genomics 20090101 |
| Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. | Current medicinal chemistry 20090101 |
| Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats. | Reproductive biology and endocrinology : RB&E 20090101 |
| [Enhancing effect of androgen receptor antagonist on gonadotropic inductors of ovulation in rats with polycystic ovaries]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101 |
| Benefit of whole pelvic radiotherapy combined with neoadjuvant androgen deprivation for the high-risk prostate cancer. | Journal of biomedicine & biotechnology 20090101 |
| Androgens and the breast. | Breast cancer research : BCR 20090101 |
| Experience with the once-yearly histrelin (GnRHa) subcutaneous implant in the treatment of central precocious puberty. | Drug design, development and therapy 20090101 |
| Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo. | Molecular cancer 20090101 |
| Molecular and biochemical effects of a kola nut extract on androgen receptor-mediated pathways. | Journal of toxicology 20090101 |
| Androgen deprivation therapy for prostate cancer: indications, contraindications and possible consequences. | F1000 medicine reports 20090101 |
| Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer. | International journal of cancer 20081215 |
| Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. | Archives of toxicology 20081201 |
| Effects of androgens on serum concentrations of gonadotropins and ovarian steroids in gilts. | Biology of reproduction 20081201 |
| [Low-dose flutamide in the treatment of hyperandrogenism in adolescents]. | Minerva pediatrica 20081201 |
| Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase. | Chemical research in toxicology 20081201 |
| Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
| Regulation of mRNAs encoding MMP-9 and MMP-2, and their inhibitors TIMP-1 and TIMP-2 by androgens in the rat ventral prostate. | Molecular and cellular endocrinology 20081106 |
| Watchful waiting beats androgen deprivation therapy in early prostate cancer. | Journal of the National Cancer Institute 20081105 |
| Nandrolone abuse decreases anxiety and impairs memory in rats via central androgenic receptors. | The international journal of neuropsychopharmacology 20081101 |
| Androgen regulation of corticotropin-releasing hormone receptor 2 (CRHR2) mRNA expression and receptor binding in the rat brain. | Experimental neurology 20081101 |
| The oxidation handicap hypothesis and the carotenoid allocation trade-off. | Journal of evolutionary biology 20081101 |
| Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice. | Hormones and behavior 20081101 |
| Hormonal regulation and characterisation of the aldehyde oxidase-like gene of hamster Harderian gland. | The Journal of steroid biochemistry and molecular biology 20081101 |
| A new allergen in the pharmaceutical industry. | Contact dermatitis 20081101 |
| Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. | Environmental health perspectives 20081101 |
| Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease. | Current cardiology reviews 20081101 |
| Docetaxel chemotherapy of Korean patients with hormone- refractory prostate cancer:comparative analysis between 1st-line and 2nd-line docetaxel. | Yonsei medical journal 20081031 |
| Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020 |
| The model anti-androgen flutamide suppresses the expression of typical male stickleback reproductive behaviour. | Aquatic toxicology (Amsterdam, Netherlands) 20081020 |
| Mechanisms involved in testosterone-induced vasodilatation in pig prostatic small arteries. | Life sciences 20081010 |
| Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
| A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate. | British journal of cancer 20081007 |
| Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02. | European urology 20081001 |
| Editorial comment on: Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02. | European urology 20081001 |
| Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells. | Endocrinology 20081001 |
| PSA kinetics provide improved prediction of survival in metastatic hormone-refractory prostate cancer. | Urology 20081001 |
| Potential role of G-protein-coupled receptor 30 (GPR30) in estradiol-17beta-stimulated IGF-I mRNA expression in bovine satellite cell cultures. | Domestic animal endocrinology 20081001 |
| Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis. | Reproductive toxicology (Elmsford, N.Y.) 20081001 |
| Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides. | Therapeutics and clinical risk management 20081001 |
| Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. | The Prostate 20080915 |
| Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters. | General and comparative endocrinology 20080915 |
| 5Alpha-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway. | Brain research 20080910 |
| Sex hormone influence on hepatitis in young male A/JCr mice infected with Helicobacter hepaticus. | Infection and immunity 20080901 |
| Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade. | The Journal of urology 20080901 |
| Effect of testosterone on morphine withdrawal syndrome in rats. | Asian journal of andrology 20080901 |
| Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers. | Biochemical pharmacology 20080901 |
| Sex-specific pathways in early cardiac response to pressure overload in mice. | Journal of molecular medicine (Berlin, Germany) 20080901 |
| Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring. | Bioorganic & medicinal chemistry 20080901 |
| Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures. | Journal of chemical information and modeling 20080901 |
| Effect of deprivation of endogenous follicle stimulating hormone on rat epididymis: a histological evaluation. | Reproductive biomedicine online 20080901 |
| Hormonal therapy for acne. | Seminars in cutaneous medicine and surgery 20080901 |
| Modulation by testosterone of an endogenous hERG potassium channel current. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
| Continuous versus six months a year maximal androgen blockade in the management of prostate cancer: a randomised study. | European urology 20080801 |
| Editorial comment on: continuous versus six months a year maximal androgen blockade in the management of prostate cancer: a randomised study. | European urology 20080801 |
| Sexual differentiation of the external genitalia and the timing of puberty in the presence of an antiandrogen in sheep. | Endocrinology 20080801 |
| Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis. | Journal of applied physiology (Bethesda, Md. : 1985) 20080801 |
| Androgen receptor: a new player associated with apoptosis and proliferation of pancreatic beta-cell in type 1 diabetes mellitus. | Apoptosis : an international journal on programmed cell death 20080801 |
| [Effects of physiological testosterone on transcription factor activity in human umbilical vein endothelial cells]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20080801 |
| Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats. | Neuroscience 20080717 |
| Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells. | Neuroreport 20080716 |
| 4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor. | Bioorganic & medicinal chemistry 20080715 |
| Effect of dihydrotestosterone on hydrogen peroxide-induced apoptosis of mouse embryonic stem cells. | Journal of cellular physiology 20080701 |
| A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor. | International journal of cancer 20080701 |
| Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells. | Domestic animal endocrinology 20080701 |
| Bioactivation of flutamide metabolites by human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
| Regulation of atherosclerotic plaque growth and stability by testosterone and its receptor via influence of inflammatory reaction. | Vascular pharmacology 20080701 |
| Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma. | Anti-cancer drugs 20080701 |
| Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| BCRP/ABCG2 in the placenta: expression, function and regulation. | Pharmaceutical research 20080601 |
| Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. | The Prostate 20080601 |
| Androgens regulate neprilysin expression: role in reducing beta-amyloid levels. | Journal of neurochemistry 20080601 |
| Antiandrogen withdrawal in castrate-refractory prostate cancer: a Southwest Oncology Group trial (SWOG 9426). | Cancer 20080601 |
| Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. | Developmental biology 20080601 |
| A functionally significant cross-talk between androgen receptor and ErbB2 pathways in estrogen receptor negative breast cancer. | Neoplasia (New York, N.Y.) 20080601 |
| Changes in gene expression following androgen receptor blockade is not equivalent to androgen ablation by castration in the rat ventral prostate. | Journal of biosciences 20080601 |
| Ten-year follow-up of radiation therapy oncology group protocol 92-02: a phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080520 |
| Altered striatal vulnerability to 3-nitropropionic acid in rats due to sex hormone levels during late phase of brain development. | Neuroscience letters 20080516 |
| A systematic review of commonly used medical treatments for hirsutism in women. | Clinical endocrinology 20080501 |
| Anabolic androgens restore mating after sexual satiety in male rats. | Pharmacology, biochemistry, and behavior 20080501 |
| Androgen-regulated cervical ripening: a structural, biomechanical, and molecular analysis. | American journal of obstetrics and gynecology 20080501 |
| p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682). | Urology 20080501 |
| A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080501 |
| Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration. | Journal of neurotrauma 20080501 |
| Endocrine gland-derived vascular endothelial growth factor in rat pancreas: genetic expression and testosterone regulation. | The Journal of endocrinology 20080501 |
| C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression. | Journal of molecular endocrinology 20080501 |
| Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna. | Environmental science and pollution research international 20080501 |
| Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats. | Biology of reproduction 20080401 |
| Clinical review: Antiandrogens for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials. | The Journal of clinical endocrinology and metabolism 20080401 |
| Clinical review: Insulin sensitizers for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials. | The Journal of clinical endocrinology and metabolism 20080401 |
| Testosterone environment of splenocytes modifies the steroidogenesis of polycystic ovary in rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401 |
| Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus. | Experimental neurology 20080401 |
| Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat. | International journal of andrology 20080401 |
| Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. | The Journal of clinical investigation 20080401 |
| Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study. | Advances in therapy 20080401 |
| Maximal androgen blockade for advanced prostate cancer. | Best practice & research. Clinical endocrinology & metabolism 20080401 |
| Levonorgestrel antagonism on estrogen-induced pituitary tumors is mediated by progesterone receptors. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401 |
| Use of ethinylestradiol/drospirenone combination in patients with the polycystic ovary syndrome. | Therapeutics and clinical risk management 20080401 |
| Leuprorelin depot injection: patient considerations in the management of prostatic cancer. | Therapeutics and clinical risk management 20080401 |
| A review of hormonal therapy for female pattern (androgenic) alopecia. | Dermatology online journal 20080315 |
| Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo. | Cancer letters 20080308 |
| Alteration in [11C]vorozole binding to aromatase in neuronal cells of rat brain induced by anabolic androgenic steroids and flutamide. | Neuroreport 20080305 |
| Orchiectomy or testosterone receptor blockade reduces intestinal mucosal damage caused by ischemia-reperfusion insult. | Pediatric surgery international 20080301 |
| Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080301 |
| Quantitative evaluation of sebum lipid components with nuclear magnetic resonance. | Journal of lipid research 20080301 |
| Early orchiopexy improves subsequent testicular development and spermatogenesis in the experimental cryptorchid rat model. | The Journal of urology 20080301 |
| Evidence for the participation of calcium in non-genomic relaxations induced by androgenic steroids in rat vas deferens. | British journal of pharmacology 20080301 |
| Dihydrotestosterone influenced numbers of healthy follicles and follicular amounts of LH receptor mRNA during the follicular phase of the estrous cycle in gilts. | Reproduction (Cambridge, England) 20080301 |
| Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network. | Epileptic disorders : international epilepsy journal with videotape 20080301 |
| Parenteral oestrogen in the treatment of prostate cancer: a systematic review. | British journal of cancer 20080226 |
| Flutamide reduced prostate cancer development and prostate stem cell antigen mRNA expression in high grade prostatic intraepithelial neoplasia. | International journal of cancer 20080215 |
| Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation. | Analytical chemistry 20080215 |
| CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance. | British journal of cancer 20080212 |
| Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway. | Clinical endocrinology 20080201 |
| Hormonal regulation of BCRP expression in human placental BeWo cells. | Pharmaceutical research 20080201 |
| Long-term treatment sequelae after external beam irradiation with or without hormonal manipulation for adenocarcinoma of the prostate: analysis of radiation therapy oncology group studies 85-31, 86-10, and 92-02. | International journal of radiation oncology, biology, physics 20080201 |
| Gonadal steroid hormones maintain the stress-induced acetylcholine release in the hippocampus: simultaneous measurements of the extracellular acetylcholine and serum corticosterone levels in the same subjects. | Endocrinology 20080201 |
| Pioglitazone (7.5 mg/day) added to flutamide-metformin in women with androgen excess: additional increments of visfatin and high molecular weight adiponectin. | Clinical endocrinology 20080201 |
| Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: long-term results of RTOG 8610. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080201 |
| Review of the histological effects of the anti-androgen, flutamide, on mouse testis. | Reproductive toxicology (Elmsford, N.Y.) 20080201 |
| Impact of sex and hormones on new cells in the developing rat hippocampus: a novel source of sex dimorphism? | The European journal of neuroscience 20080201 |
| Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial. | JAMA 20080123 |
| Androgen resistance in prostate cancer. | British journal of cancer 20080115 |
| Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer. | Prostate cancer and prostatic diseases 20080101 |
| In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat. | Reproductive toxicology (Elmsford, N.Y.) 20080101 |
| Evidence that androgens regulate early developmental events, prior to sexual differentiation. | Endocrinology 20080101 |
| Potassium channels are involved in testosterone-induced vasorelaxation of human umbilical artery. | Naunyn-Schmiedeberg's archives of pharmacology 20080101 |
| The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells. | Reproductive toxicology (Elmsford, N.Y.) 20080101 |
| Clinical results of isolated tibial component revisions with femoral component retention. | The Journal of arthroplasty 20080101 |
| Alterations of Sertoli cell activity in the long-term testicular germ cell death process induced by fetal androgen disruption. | The Journal of endocrinology 20080101 |
| Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs? | Radiation oncology (London, England) 20080101 |
| 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) disrupts the estrogen-androgen balance regulating the growth of hormone-dependent breast cancer cells. | Breast cancer research : BCR 20080101 |
| Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence. | PPAR research 20080101 |
| Testosterone influences renal electrolyte excretion in SHR/y and WKY males. | BMC physiology 20080101 |
| Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy. | BMC cancer 20080101 |
| Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer: part 2. Final evaluation of the Scandinavian Prostatic Cancer Group (SPCG) Study No. 5. | Scandinavian journal of urology and nephrology 20080101 |
| Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. | Breast cancer research : BCR 20080101 |
| Characterization of androgen regulation of ZEB-1 and PSA in 22RV1 prostate cancer cells. | Advances in experimental medicine and biology 20080101 |
| The relationship between the biochemical control outcomes and the quality of planning of high-dose rate brachytherapy as a boost to external beam radiotherapy for locally and locally advanced prostate cancer using the RTOG-ASTRO Phoenix definition. | International journal of medical sciences 20080101 |
| Bench-to-bedside review: latest results in hemorrhagic shock. | Critical care (London, England) 20080101 |
| Evaluation of resistance index in patients with prostate cancer. | Anticancer research 20080101 |
| Recent advances in the investigation of curcuminoids. | Chinese medicine 20080101 |
| A dramatic, objective antiandrogen withdrawal response: case report and review of the literature. | Journal of hematology & oncology 20080101 |
| Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells. | Molecular cancer 20080101 |
| Selective androgen receptor modulators in preclinical and clinical development. | Nuclear receptor signaling 20080101 |
| Strategies for prostate cancer prevention: Review of the literature. | Indian journal of urology : IJU : journal of the Urological Society of India 20080101 |
| Quality of life measurement in bone metastases: A literature review. | Journal of pain research 20080101 |
| The effect of sodium valproate on the biochemical parameters of reproductive function in male albino Wistar rats. | Indian journal of pharmacology 20080101 |
| Aspirin and hormone therapy for prostate cancer. | The New England journal of medicine 20071227 |
| The anatomy of the cremaster muscle during inguinoscrotal testicular descent in the rat. | Journal of pediatric surgery 20071201 |
| Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat. | Environmental health perspectives 20071201 |
| The efficacy of neoadjuvant androgen deprivation therapy as a prostate volume reduction before brachytherapy for clinically localized prostate cancer. | Acta medica Okayama 20071201 |
| Antiandrogen pretreatment alters cocaine pharmacokinetics in men. | Journal of addiction medicine 20071201 |
| Weekly administration of docetaxel in combination with estramustine and celecoxib in patients with advanced hormone-refractory prostate cancer: final results from a phase II study. | British journal of cancer 20071105 |
| Testosterone directly induces progesterone production and interacts with physiological concentrations of LH to increase granulosa cell progesterone production in laying hens (Gallus domesticus). | Animal reproduction science 20071101 |
| Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20071101 |
| Dystroglycan expression is reduced during prostate tumorigenesis and is regulated by androgens in prostate cancer cells. | Journal of cellular physiology 20071101 |
| Evaluation of the antiandrogenic effects of flutamide, DDE, and linuron in the weanling rat assay using organ weight, histopathological, and proteomic approaches. | Toxicological sciences : an official journal of the Society of Toxicology 20071101 |
| Inhibition of oxidative-stress-induced platelet aggregation by androgen at physiological levels via its receptor is associated with the reduction of thromboxane A2 release from platelets. | Steroids 20071101 |
| A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists. | Analytical and bioanalytical chemistry 20071101 |
| Association of body mass index with response and survival in men with metastatic prostate cancer: Southwest Oncology Group trials 8894 and 9916. | The Journal of urology 20071101 |
| Novel flutamide regulated genes in the rat ventral prostate: differential modulation of their expression by castration and flutamide treatments. | Asian journal of andrology 20071101 |
| Flutamide metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotype. | European journal of endocrinology 20071101 |
| Activation of the androgen receptor alters the intracellular calcium response to glutamate in primary hippocampal neurons and modulates sarco/endoplasmic reticulum calcium ATPase 2 transcription. | Neuroscience 20071012 |
| Expression pattern of sulfated glycoprotein-2 (SGP-2) mRNA in rat testes exposed to endocrine disruptors. | The Journal of reproduction and development 20071001 |
| Androgen receptor blockade in experimental combination therapy of pancreatic cancer. | The Journal of surgical research 20071001 |
| PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor. | The Journal of steroid biochemistry and molecular biology 20071001 |
| The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score. | The Journal of urology 20071001 |
| Suspected cross-hepatotoxicity of flutamide and cyproterone acetate. | Liver international : official journal of the International Association for the Study of the Liver 20071001 |
| Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites. | Chemical research in toxicology 20071001 |
| Pharmacological causes of hyperprolactinemia. | Therapeutics and clinical risk management 20071001 |
| Evaluation of the rodent Hershberger bioassay: testing of coded chemicals and supplementary molecular-biological and biochemical investigations. | Toxicology 20070924 |
| Racial differences in CYP3A4 genotype and survival among men treated on Radiation Therapy Oncology Group (RTOG) 9202: a phase III randomized trial. | International journal of radiation oncology, biology, physics 20070901 |
| Are steroids obligatory mediators of luteinizing hormone/human chorionic gonadotropin-triggered resumption of meiosis in mammals? | Endocrinology 20070901 |
| Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism: a 12-month, double-blind, parallel clinical trial. | The Journal of clinical endocrinology and metabolism 20070901 |
| Persisting benefits 12-18 months after discontinuation of pubertal metformin therapy in low birthweight girls. | Clinical endocrinology 20070901 |
| Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes. | Journal of veterinary science 20070901 |
| Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening. | Chemical research in toxicology 20070901 |
| Neuroendocrine effects of androgens in adult polycystic ovary syndrome and female puberty. | Seminars in reproductive medicine 20070901 |
| Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior. | Nature clinical practice. Oncology 20070901 |
| The modulatory role of androgens and progestins in the induction of vasorelaxation in human umbilical artery. | Life sciences 20070901 |
| Fatal spontaneous tumor lysis syndrome in a patient with metastatic, androgen-independent prostate cancer. | Southern medical journal 20070901 |
| Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals. | Urology 20070901 |
| [Effects of testosterone on extracellular signal-regulated kinase 1/2 phosphorylation in human umbilical vein endothelial cells]. | Zhonghua nan ke xue = National journal of andrology 20070901 |
| Combined androgen blockade in advanced prostate cancer: looking back to move forward. | Clinical genitourinary cancer 20070901 |
| Efficacy of the combination of long-acting release octreotide and tamoxifen in patients with advanced hepatocellular carcinoma: a randomised multicentre phase III study. | British journal of cancer 20070828 |
| Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures. | Brain research 20070824 |
| Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells. | Oncogene 20070823 |
| Design, synthesis, and in vivo SAR of a novel series of pyrazolines as potent selective androgen receptor modulators. | Journal of medicinal chemistry 20070809 |
| The use of metabolomics for the discovery of new biomarkers of effect. | Toxicology letters 20070730 |
| The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model. | Breast cancer research and treatment 20070701 |
| Receptor-mediated suppression of cardiac heat-shock protein 72 expression by testosterone in male rat heart. | Endocrinology 20070701 |
| Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
| Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures. | Toxicological sciences : an official journal of the Society of Toxicology 20070701 |
| The critical time window for androgen-dependent development of the Wolffian duct in the rat. | Endocrinology 20070701 |
| A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells. | Molecular cancer therapeutics 20070701 |
| Differential expression of 3beta-hydroxysteroid dehydrogenase mRNA in rat testes exposed to endocrine disruptors. | The Journal of reproduction and development 20070601 |
| Gender dimorphism in the myeloid differentiation of bone marrow precursor cells in a murine host bearing a T cell lymphoma. | Journal of reproductive immunology 20070601 |
| Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. | Molecular pharmacology 20070601 |
| Flutamide and cyproterone acetate exert agonist effects: induction of androgen receptor-dependent neuroprotection. | Endocrinology 20070601 |
| Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors. | The Prostate 20070601 |
| Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells. | Biological & pharmaceutical bulletin 20070601 |
| Reciprocal regulation of 5alpha-dihydrotestosterone, interleukin-6 and interleukin-8 during proliferation of epithelial ovarian carcinoma. | Cancer biology & therapy 20070601 |
| Claudin-11 expression and localisation is regulated by androgens in rat Sertoli cells in vitro. | Reproduction (Cambridge, England) 20070601 |
| Testosterone inhibits matrix metalloproteinase-1 production in human endometrial stromal cells in vitro. | Reproduction (Cambridge, England) 20070601 |
| [Mediastinal lymph nodes during the course of a metastatic prostate cancer]. | Actas urologicas espanolas 20070601 |
| Female pattern hair loss: current treatment concepts. | Clinical interventions in aging 20070601 |
| Androgen disruption of early development in Qurt strain medaka (Oryzias latipes). | Aquatic toxicology (Amsterdam, Netherlands) 20070515 |
| Effects of long-term flutamide treatment during development in zebra finches. | Neuroscience letters 20070511 |
| Impact of testosterone on cardiac L-type calcium channels and Ca2+ sparks: acute actions antagonize chronic effects. | Cell calcium 20070501 |
| Role of androgens in fetal testis development and dysgenesis. | Endocrinology 20070501 |
| Combined low-dose pioglitazone, flutamide, and metformin for women with androgen excess. | The Journal of clinical endocrinology and metabolism 20070501 |
| Correlation between protein accumulation profiles and conventional toxicological findings using a model antiandrogenic compound, flutamide. | Toxicological sciences : an official journal of the Society of Toxicology 20070501 |
| Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression. | The Prostate 20070501 |
| Vitiliginous lesions after photosensitive dermatitis due to flutamide. | Journal of the European Academy of Dermatology and Venereology : JEADV 20070501 |
| Sex differences in angiotensin II- induced hypertension. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070501 |
| The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses: phase 2 dose-response studies. | Environmental health perspectives 20070501 |
| Region-specific mechanisms for testosterone-induced Fos in hamster brain. | Brain research 20070413 |
| Automated determination of flutamide by a validated flow-injection method: application to dissolution studies of pharmaceutical tablets. | Journal of pharmaceutical and biomedical analysis 20070411 |
| Effect of selected fluorinated drugs in a 'ringing' gel on rheological behaviour and skin permeation. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401 |
| Effects of various pesticides on human 5alpha-reductase activity in prostate and LNCaP cells. | Toxicology in vitro : an international journal published in association with BIBRA 20070401 |
| Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane. | Bone 20070401 |
| Search for residual prostate cancer on pT0 radical prostatectomy after positive biopsy. | Virchows Archiv : an international journal of pathology 20070401 |
| Cognitive performance in rhesus monkeys varies by sex and prenatal androgen exposure. | Hormones and behavior 20070401 |
| Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis. | Biological & pharmaceutical bulletin 20070401 |
| Dehydroepiandrosterone improves murine osteoblast growth and bone tissue morphometry via mitogen-activated protein kinase signaling pathway independent of either androgen receptor or estrogen receptor. | Journal of molecular endocrinology 20070401 |
| Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401 |
| Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons. | Endocrine 20070401 |
| Testosterone and oxidative stress: the oxidation handicap hypothesis. | Proceedings. Biological sciences 20070322 |
| Cellular and extracellular behavior in the gerbil (Meriones unguiculatus) ventral prostate following different types of castration and the consequences of testosterone replacement. | Cell biology international 20070301 |
| Ligand-specific dynamics of the androgen receptor at its response element in living cells. | Molecular and cellular biology 20070301 |
| Estrogen receptor (ER) agonists and androgen receptor (AR) antagonists in effluents from Norwegian North Sea oil production platforms. | Marine pollution bulletin 20070301 |
| The effect of brachytherapy, external beam irradiation and hormonal therapy on prostate volume. | The Journal of urology 20070301 |
| Curcumin downregulates homeobox gene NKX3.1 in prostate cancer cell LNCaP. | Acta pharmacologica Sinica 20070301 |
| The effect of testosterone, dihydrotestosterone and oestradiol on the re-initiation of spermatogenesis in the adult photoinhibited Djungarian hamster. | The Journal of endocrinology 20070301 |
| Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women. | The Journal of endocrinology 20070301 |
| Long-term effectiveness of luteinizing hormone-releasing hormone agonist or antiandrogen monotherapy in elderly men with localized prostate cancer (T1-2): a retrospective study. | Asian journal of andrology 20070301 |
| A novel amphibian tier 2 testing protocol: a 30-week exposure of Xenopus tropicalis to the antiandrogen flutamide. | Environmental toxicology and chemistry 20070301 |
| Effects of flutamide as a second-line agent for maximum androgen blockade of hormone refractory prostate cancer. | International journal of urology : official journal of the Japanese Urological Association 20070301 |
| Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish. | Aquatic toxicology (Amsterdam, Netherlands) 20070227 |
| Hypothalamus region-specific global gene expression profiling in early stages of central endocrine disruption in rat neonates injected with estradiol benzoate or flutamide. | Developmental neurobiology 20070215 |
| Androgens' performance-enhancing effects in the inhibitory avoidance and water maze tasks may involve actions at intracellular androgen receptors in the dorsal hippocampus. | Neurobiology of learning and memory 20070201 |
| Estrogen-induced upregulation of AR expression and enhancement of AR nuclear translocation in mouse fallopian tubes in vivo. | American journal of physiology. Endocrinology and metabolism 20070201 |
| Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells. | The Prostate 20070201 |
| Expression of galectin-3 and its regulation in the testes. | International journal of andrology 20070201 |
| Quantitative determination of lobe specificity of mRNA expression of androgen-dependent genes in the rat prostate gland. | Endocrine journal 20070201 |
| Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway. | Annals of surgery 20070201 |
| [Development of novel nuclear receptor ligands based on receptor-folding inhibition hypothesis]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070201 |
| Clinical efficacy of alternative antiandrogen therapy in Japanese men with relapsed prostate cancer after first-line hormonal therapy. | International journal of urology : official journal of the Japanese Urological Association 20070201 |
| Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells. | Environmental health perspectives 20070201 |
| Hormone ablation therapy: lightening the load for today's prostate cancer patient. | Urologic nursing 20070201 |
| The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay. | Biochemistry 20070123 |
| Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay. | Chemosphere 20070101 |
| Surgical and chemical castration induce differential histological response in prostate lobes of Mongolian gerbil. | Micron (Oxford, England : 1993) 20070101 |
| Androgen and the elaborate courtship behavior of a tropical lekking bird. | Hormones and behavior 20070101 |
| Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma. | Histology and histopathology 20070101 |
| Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101 |
| Androgen decreases osteoprotegerin expression in prostate cancer cells. | Prostate cancer and prostatic diseases 20070101 |
| Phase II study of neoadjuvant androgen deprivation followed by external-beam radiotherapy with 9 months of androgen deprivation for intermediate- to high-risk localized prostate cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070101 |
| Influence for testicular development and histological peculiarity in the testes of flutamide-induced cryptorchid rat model. | International journal of urology : official journal of the Japanese Urological Association 20070101 |
| Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. | Cancer research 20070101 |
| Early effects of pharmacological androgen deprivation in human prostate cancer. | BJU international 20070101 |
| Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice. | Reproduction (Cambridge, England) 20070101 |
| Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis. | Arthritis research & therapy 20070101 |
| Squamous cell carcinoma of the prostate: long-term survival after combined chemo-radiation. | Radiation oncology (London, England) 20070101 |
| Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation. | Thrombosis research 20070101 |
| Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model. | Prostate cancer and prostatic diseases 20070101 |
| [Endocrine disruptor compounds and their role in the developmental programming of the reproductive axis]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20070101 |
| Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion. | Journal of applied toxicology : JAT 20070101 |
| A phase II trial of docetaxel and erlotinib as first-line therapy for elderly patients with androgen-independent prostate cancer. | BMC cancer 20070101 |
| Can a single model explain both breast cancer and prostate cancer? | Theoretical biology & medical modelling 20070101 |
| No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro. | Radiation oncology (London, England) 20070101 |
| Comparison of three instrumental methods for the objective evaluation of radiotherapy induced erythema in breast cancer patients and a study of the effect of skin lotions. | Acta oncologica (Stockholm, Sweden) 20070101 |
| Pathogenesis of prostate cancer and hormone refractory prostate cancer. | Indian journal of urology : IJU : journal of the Urological Society of India 20070101 |
| Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines. | Indian journal of urology : IJU : journal of the Urological Society of India 20070101 |
| Sex steroids modulate changes in social and sexual preference during juvenile development in zebra finches. | Hormones and behavior 20061201 |
| Testosterone stimulates the primary to secondary follicle transition in bovine follicles in vitro. | Biology of reproduction 20061201 |
| Androgens differentially potentiate mouse intestinal smooth muscle by nongenomic activation of polyamine synthesis and Rho kinase activation. | Endocrinology 20061201 |
| Cancer-specific mortality after radiation therapy with short-course hormonal therapy or radical prostatectomy in men with localized, intermediate-risk to high-risk prostate cancer. | Cancer 20061201 |
| Role of 5 alpha-reductase inhibitors in the management of prostate cancer. | Clinical interventions in aging 20061201 |
| [Bone metastasis of prostatic cancer imitating Paget's sarcoma]. | Deutsche medizinische Wochenschrift (1946) 20061110 |
| Anti-progestogenic effect of flutamide on uterine expression of calbindin-D9k mRNA and protein in immature mice. | Reproductive toxicology (Elmsford, N.Y.) 20061101 |
| Long-term and immediate effect of testosterone on single T-type calcium channel in neonatal rat cardiomyocytes. | Endocrinology 20061101 |
| Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20061101 |
| The effect of flutamide on systemic and renal hemodynamics in Zucker diabetic rats: paradoxic renal vasodilator response to endothelin-1 and TXA2 receptor activation in female sex. | Journal of cardiovascular pharmacology 20061101 |
| Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage. | Cytokine 20061101 |
| Multiple hormonal activities of UV filters and comparison of in vivo and in vitro estrogenic activity of ethyl-4-aminobenzoate in fish. | Aquatic toxicology (Amsterdam, Netherlands) 20061012 |
| Improving the outcome of patients with castration-resistant prostate cancer through rational drug development. | British journal of cancer 20061009 |
| Dopamine agonists, anti-progestins, anti-androgens, long-term-release GnRH agonists and anti-estrogens in canine reproduction: a review. | Theriogenology 20061001 |
| Androgen-dependent mechanisms of Wolffian duct development and their perturbation by flutamide. | Endocrinology 20061001 |
| Expression profiling of endocrine-disrupting compounds using a customized Cyprinus carpio cDNA microarray. | Toxicological sciences : an official journal of the Society of Toxicology 20061001 |
| Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study. | The Journal of clinical endocrinology and metabolism 20061001 |
| Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. | Journal of leukocyte biology 20061001 |
| Results of radiation therapy combined with neoadjuvant hormonal therapy for stage III prostate cancer: comparison of two different definitions of PSA failure. | International journal of clinical oncology 20061001 |
| Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression. | Urology 20061001 |
| Bioactivation and hepatotoxicity of nitroaromatic drugs. | Current drug metabolism 20061001 |
| [Histological investigation of prostate cancer treated with hormonal agents]. | Hinyokika kiyo. Acta urologica Japonica 20061001 |
| The effect of androgen blockade on granulosa cell estradiol production after follicle-stimulating hormone stimulation in women with polycystic ovary syndrome. | The Journal of clinical endocrinology and metabolism 20060901 |
| [Keyrole of endocrinology in the victory against prostate cancer]. | Bulletin du cancer 20060901 |
| Development of a stickleback kidney cell culture assay for the screening of androgenic and anti-androgenic endocrine disrupters. | Aquatic toxicology (Amsterdam, Netherlands) 20060823 |
| A systematic review of the effectiveness of docetaxel and mitoxantrone for the treatment of metastatic hormone-refractory prostate cancer. | British journal of cancer 20060821 |
| Identification of a lead pharmacophore for the development of potent nuclear receptor modulators as anticancer and X syndrome disease therapeutic agents. | Bioorganic & medicinal chemistry letters 20060815 |
| Castration prevents suppression of MHC class II (Ia) expression on macrophages after trauma-hemorrhage. | Journal of applied physiology (Bethesda, Md. : 1985) 20060801 |
| Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats. | Hormones and behavior 20060801 |
| PTOV1: a novel testosterone-induced atherogenic gene in human aorta. | The Journal of pathology 20060801 |
| Androgen and anti-androgen treatment modulates androgen receptor activity and DJ-1 stability. | The Prostate 20060801 |
| Sex differences in otoacoustic emissions measured in rhesus monkeys (Macaca mulatta). | Hormones and behavior 20060801 |
| Antiandrogen treatments in locally advanced prostate cancer: are they all the same? | Journal of cancer research and clinical oncology 20060801 |
| The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses. Phase 1: use of a potent agonist and a potent antagonist to test the standardized protocol. | Environmental health perspectives 20060801 |
| Chiral dimethylamine flutamide derivatives--modeling, synthesis, androgen receptor affinities and carbon-11 labeling. | Nuclear medicine and biology 20060801 |
| Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide. | Nuclear medicine and biology 20060801 |
| Possibility of recovery of estrogen sensitivity following high-dose glucocorticoid therapy in a patient with hormone-refractory prostate cancer. | International journal of clinical oncology 20060801 |
| Impact of neoadjuvant hormonal therapy on dose-volume histograms in patients with localized prostate cancer under radical radiation therapy. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060801 |
| [DHEA inhibits apoptosis of murine OB through MAPK signaling pathways independent of either ARs or ERs]. | Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060801 |
| Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis. | Biochemical and biophysical research communications 20060721 |
| Androgen and fibroblast growth factor 8 (FGF8) downregulation of thrombospondin 1 (TSP1) in mouse breast cancer cells. | Molecular and cellular endocrinology 20060711 |
| Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701 |
| In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. | Toxicological sciences : an official journal of the Society of Toxicology 20060701 |
| Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
| Anti-androgen flutamide affects gonadal development and reproduction in medaka (Oryzias latipes). | Marine environmental research 20060701 |
| Prostate androgen-regulated gene: a novel potential target for androgen-independent prostate cancer therapy. | Asian journal of andrology 20060701 |
| Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in nonobese adolescents and women. | Fertility and sterility 20060701 |
| Use of antiandrogens as therapy for women with polycystic ovary syndrome. | Fertility and sterility 20060701 |
| Prenatal growth restraint followed by catch-up of weight: a hyperinsulinemic pathway to polycystic ovary syndrome. | Fertility and sterility 20060701 |
| [The effects of flutamide on the full gene expression of early testis development of embryonic period male SD]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060701 |
| GREB1 is a novel androgen-regulated gene required for prostate cancer growth. | The Prostate 20060601 |
| Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity. | Endocrinology 20060601 |
| Effects of neonatal exposure to 4-tert-octylphenol, diethylstilbestrol, and flutamide on steroidogenesis in infantile rat testis. | Toxicological sciences : an official journal of the Society of Toxicology 20060601 |
| Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry. | Drug metabolism and disposition: the biological fate of chemicals 20060601 |
| The role of sex steroids in courtship, pairing and pairing behaviors in the socially monogamous zebra finch. | Hormones and behavior 20060601 |
| Evaluation of a commercial kit for measuring vitellogenin in the fathead minnow (Pimephales promelas). | Ecotoxicology and environmental safety 20060601 |
| Testosterone antagonist (flutamide) blocks ovulation and preovulatory surges of progesterone, luteinizing hormone and oestradiol in laying hens. | Reproduction (Cambridge, England) 20060601 |
| Maximal androgen blockade for the treatment of metastatic prostate cancer--a systematic review. | Current oncology (Toronto, Ont.) 20060601 |
| Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial. | Investigational new drugs 20060501 |
| DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells. | American journal of physiology. Endocrinology and metabolism 20060501 |
| The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor. | Molecular endocrinology (Baltimore, Md.) 20060501 |
| Androgen effects on hippocampal CA1 spine synapse numbers are retained in Tfm male rats with defective androgen receptors. | Endocrinology 20060501 |
| Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients. | Drug metabolism and disposition: the biological fate of chemicals 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Adverse effects to quality of life arising from treatment can recover with intermittent androgen suppression in men with prostate cancer. | European journal of cancer (Oxford, England : 1990) 20060501 |
| Testosterone induces neuroprotection from oxidative stress. Effects on catalase activity and 3-nitro-L-tyrosine incorporation into alpha-tubulin in a mouse neuroblastoma cell line. | Archives italiennes de biologie 20060501 |
| Recent progress in hormonal therapy for advanced prostate cancer. | Current opinion in urology 20060501 |
| Expression of functional aromatase in the epididymis: role of androgens and LH in modulation of expression and activity. | Molecular and cellular endocrinology 20060425 |
| Fatal liver complications with flutamide. | Lancet (London, England) 20060408 |
| Hirsutism. | The New England journal of medicine 20060406 |
| Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system. | Pharmacoepidemiology and drug safety 20060401 |
| Luteinizing hormone, follicle stimulating hormone, and gonadotropin releasing hormone mRNA expression of Xenopus laevis in response to endocrine disrupting compounds affecting reproductive biology. | General and comparative endocrinology 20060401 |
| The magnitude of early castration-induced primary tumour regression in prostate cancer does not predict clinical outcome. | European urology 20060401 |
| Dihydrotestosterone differentially modulates the mitogen-activated protein kinase and the phosphoinositide 3-kinase/Akt pathways through the nuclear and novel membrane androgen receptor in C6 cells. | Endocrinology 20060401 |
| COMPRENDO: Focus and approach. | Environmental health perspectives 20060401 |
| Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens. | Environmental health perspectives 20060401 |
| Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women. | Nature clinical practice. Endocrinology & metabolism 20060401 |
| Marked sexual dimorphism of lacrimal gland peroxidase in hamster: repression by androgens and estrogens. | Biochemical and biophysical research communications 20060324 |
| Early initiation of salvage hormone therapy influences survival in patients who failed initial radiation for locally advanced prostate cancer: A secondary analysis of RTOG protocol 86-10. | International journal of radiation oncology, biology, physics 20060315 |
| Cloning and expression analysis of androgen receptor gene in chicken embryogenesis. | FEBS letters 20060306 |
| TNF-alpha-related apoptosis-inducing ligand decoy receptor DcR2 is targeted by androgen action in the rat ventral prostate. | Journal of cellular physiology 20060301 |
| A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues. | Chemical research in toxicology 20060301 |
| [Effect of dihydrotestosterone on the transcriptions and expressions of Smad3 and Smad4 in LNCaP cell line]. | Zhonghua nan ke xue = National journal of andrology 20060301 |
| [Impact of flutamide on sex differentiation in rats]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060301 |
| Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice. | Journal of gastroenterology 20060301 |
| Androgen-induced yawning in rhesus monkey females is reversed with a nonsteroidal anti-androgen. | Hormones and behavior 20060201 |
| Discontinuous low-dose flutamide-metformin plus an oral or a transdermal contraceptive in patients with hyperinsulinaemic hyperandrogenism: normalizing effects on CRP, TNF-alpha and the neutrophil/lymphocyte ratio. | Human reproduction (Oxford, England) 20060201 |
| Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1. | Journal of leukocyte biology 20060201 |
| The xenoestrogen bisphenol A in the Hershberger assay: androgen receptor regulation and morphometrical reactions indicate no major effects. | The Journal of steroid biochemistry and molecular biology 20060201 |
| The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201 |
| Unfaithfulness and promiscuity of a mutant androgen receptor in a hormone-refractory prostate cancer. | Cellular and molecular life sciences : CMLS 20060201 |
| Germ cell atypia in undescended testes hinges on the aetiology of cryptorchidism but not the abdominal location per se. | International journal of andrology 20060201 |
| A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene-related peptide. | Journal of pediatric surgery 20060201 |
| Prenatal androgen blockade accelerates pubertal development in male rhesus monkeys. | Psychoneuroendocrinology 20060101 |
| Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1. | American journal of physiology. Heart and circulatory physiology 20060101 |
| Both testosterone and follicle-stimulating hormone independently inhibit spermatogonial differentiation in irradiated rats. | Endocrinology 20060101 |
| Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. | Endocrinology 20060101 |
| Long-term hormone therapy and radiation is cost-effective for patients with locally advanced prostate carcinoma. | Cancer 20060101 |
| A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer. | Journal of translational medicine 20060101 |
| Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in non-obese adolescents and women. | Human reproduction update 20060101 |
| The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060101 |
| Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats. | BMC pharmacology 20060101 |
| Androgen modulation of hippocampal synaptic plasticity. | Neuroscience 20060101 |
| Effects of prenatal flutamide on testicular development, androgen production and fertility in rats. | Urologia internationalis 20060101 |
| Gene expression profiling of androgen receptor antagonists in the rat fetal testis reveals few common gene targets. | Journal of biochemical and molecular toxicology 20060101 |
| [Testosterone inhibits the contractile responses to phenylephrine associated with the release of intracellular calcium in rat aorta]. | Gaceta medica de Mexico 20060101 |
| The role of steroids in follicular growth. | Reproductive biology and endocrinology : RB&E 20060101 |
| Contributions of androgen and estrogen to fetal programming of ovarian dysfunction. | Reproductive biology and endocrinology : RB&E 20060101 |
| Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer. | Anticancer research 20060101 |
| DHEA-induced antiproliferative effect in MCF-7 cells is androgen- and estrogen receptor-independent. | Cancer journal (Sudbury, Mass.) 20060101 |
| Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group. | BMC cancer 20060101 |
| The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome. | Human reproduction update 20060101 |
| Diagnosis and management of polycystic ovary syndrome: a practical guide. | Drugs 20060101 |
| Flutamide in men with prostatic intraepithelial neoplasia: a randomized, placebo-controlled chemoprevention trial. | American journal of therapeutics 20060101 |
| The limited significance of a longer duration of neoadjuvant hormonal therapy prior to radical prostatectomy for high-risk prostate cancer in Japanese men. | Urologia internationalis 20060101 |
| Finasteride induced depression: a prospective study. | BMC clinical pharmacology 20060101 |
| Regulation of human endometrial function: mechanisms relevant to uterine bleeding. | Reproductive biology and endocrinology : RB&E 20060101 |
| Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs). | Reproductive biology and endocrinology : RB&E 20060101 |
| Sex as a factor in conversion from laparoscopic cholecystectomy to open surgery. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101 |
| [Effect of combined application of the synthetic luteinizing hormone-releasing hormone agonist and nonsteroidal antiandrogen on the reproductive system of male rats]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101 |
| Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS). | PPAR research 20060101 |
| The individualization of cancer therapy: the unexpected role of p53. | Transactions of the American Clinical and Climatological Association 20060101 |
| Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro. | Toxicology 20051215 |
| An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics. | Toxicology 20051215 |
| Identification of steroid derivatives that function as potent antiandrogens. | International journal of cancer 20051210 |
| PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage. | American journal of physiology. Heart and circulatory physiology 20051201 |
| Alteration of transforming growth factor-beta signaling system expression in adult rat germ cells with a chronic apoptotic cell death process after fetal androgen disruption. | Endocrinology 20051201 |
| Cancer treatment and pharmacogenetics of cytochrome P450 enzymes. | Investigational new drugs 20051201 |
| Effect of epidermal growth factor on spermatogenesis in the cryptorchid rat. | The Journal of urology 20051201 |
| Change of the cell cycle after flutamide treatment in prostate cancer cells and its molecular mechanism. | Asian journal of andrology 20051201 |
| Sex differences in juvenile rhesus macaque (Macaca mulatta) agonistic screams: life history differences and effects of prenatal androgens. | Developmental psychobiology 20051201 |
| Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201 |
| Co-activator and co-repressor interplay on the human androgen receptor. | Andrologia 20051201 |
| Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study. | Fertility and sterility 20051201 |
| Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight. | Saudi medical journal 20051201 |
| Polycystic ovary syndrome. | Clinical evidence 20051201 |
| Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl. | The Journal of cell biology 20051121 |
| Prostate cancer PET bioprobes: synthesis of [18F]-radiolabeled hydroxyflutamide derivatives. | Bioorganic & medicinal chemistry 20051115 |
| Androgen receptor modifications in prostate cancer cells upon long-termandrogen ablation and antiandrogen treatment. | International journal of cancer 20051101 |
| Characterization of a novel rat epididymal cell line to study epididymal function. | Endocrinology 20051101 |
| Induction of liver cytochrome P450 1A2 expression by flutamide in rats. | Acta pharmacologica Sinica 20051101 |
| Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial. | The Lancet. Oncology 20051101 |
| Imaging androgen receptor function during flutamide treatment in the LAPC9 xenograft model. | Molecular cancer therapeutics 20051101 |
| Mouse model of male germ cell apoptosis in response to a lack of hormonal stimulation. | Indian journal of experimental biology 20051101 |
| The evaluation and treatment of hirsute women. | Women's health (London, England) 20051101 |
| Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells. | Biology of reproduction 20051001 |
| Mechanism of androgen-induced thymic atrophy in the wall lizard, Hemidactylus flaviviridis: an in vitro study. | General and comparative endocrinology 20051001 |
| Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate. | Endocrinology 20051001 |
| A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy. | BJU international 20051001 |
| Clinical outcome of maximum androgen blockade using flutamide as second-line hormonal therapy for hormone-refractory prostate cancer. | BJU international 20051001 |
| Androgen receptor-mediated regulation of the alpha-subunit of the epithelial sodium channel in human kidney. | Hypertension (Dallas, Tex. : 1979) 20051001 |
| [Experience in treating advanced prostate cancer with bladder outlet obstruction]. | Ai zheng = Aizheng = Chinese journal of cancer 20051001 |
| [Usefulness and positioning of MAB therapy for prostate cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade with flutamide? | Urology 20051001 |
| [Long term survival results in advanced prostate cancer treated with combined androgen blockade]. | Zhonghua nan ke xue = National journal of andrology 20051001 |
| Predictive factors for skeletal complications in hormone-refractory prostate cancer patients with metastatic bone disease. | British journal of cancer 20050919 |
| Antiandrogens prevent stable DNA-binding of the androgen receptor. | Journal of cell science 20050915 |
| Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers. | Journal of cellular physiology 20050901 |
| High neutrophil count in girls and women with hyperinsulinaemic hyperandrogenism: normalization with metformin and flutamide overcomes the aggravation by oral contraception. | Human reproduction (Oxford, England) 20050901 |
| The ontogeny of the urogenital system of the spotted hyena (Crocuta crocuta Erxleben). | Biology of reproduction 20050901 |
| Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors. | Psychoneuroendocrinology 20050901 |
| The partial female to male sex reversal in Wnt-4-deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action. | Endocrinology 20050901 |
| Circulating antiandrogenic activity in children with congenital adrenal hyperplasia during peroral flutamide treatment. | The Journal of clinical endocrinology and metabolism 20050901 |
| Antiviral effect of dehydroepiandrosterone on Japanese encephalitis virus infection. | The Journal of general virology 20050901 |
| Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo. | Journal of cardiovascular pharmacology 20050901 |
| Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy. | Urology 20050901 |
| Acquisition of androgen independence by human prostate epithelial cells during arsenic-induced malignant transformation. | Environmental health perspectives 20050901 |
| Saccharomyces cerevisiae intervention for relieving flutamide-induced hepatotoxicity in male rats. | Die Pharmazie 20050901 |
| Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels. | Biology of reproduction 20050801 |
| Simultaneous treatment with an aromatase inhibitor and an anti-androgen decreases the likelihood of dawn song in free-living male great tits, Parus major. | Hormones and behavior 20050801 |
| Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches. | Langenbeck's archives of surgery 20050801 |
| Prenatal blockade of androgen receptors reduces the number of intromissions needed to induce conditioned place preference after paced mating in female rats. | Pharmacology, biochemistry, and behavior 20050801 |
| Separating behavioral and physiological mechanisms in testosterone-mediated trade-offs. | The American naturalist 20050801 |
| Decrease in anogenital distance among male infants with prenatal phthalate exposure. | Environmental health perspectives 20050801 |
| Evaluation of general behavior, memory, learning performance, and brain sexual differentiation in F1 offspring males of rats treated with flutamide during late gestation. | The Journal of toxicological sciences 20050801 |
| Anti-androgen induced inhibition of testicular descent is associated with a decrease in sympathetic tonus. | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20050801 |
| An index of local sensitivity to nonignorable drop-out in longitudinal modelling. | Statistics in medicine 20050730 |
| The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. | Proceedings of the National Academy of Sciences of the United States of America 20050712 |
| Absence of hepatotoxicity after long-term, low-dose flutamide in hyperandrogenic girls and young women. | Human reproduction (Oxford, England) 20050701 |
| Androgen action on hepatic vitellogenin synthesis in the eel, Anguilla japonica is suppressed by an androgen receptor antagonist. | The Journal of steroid biochemistry and molecular biology 20050701 |
| Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease. | Journal of the American Society of Nephrology : JASN 20050701 |
| Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors. | Surgery 20050701 |
| [Toxic hepatitis after flutamide treatment]. | Atencion primaria 20050630 |
| Gene expression changes in rat prostate after activation or blocking of the androgen and estrogen receptor. | Molecular and cellular endocrinology 20050615 |
| Medroxyprogesterone acetate and dihydrotestosterone induce coronary hyperreactivity in intact male rhesus monkeys. | The Journal of clinical endocrinology and metabolism 20050601 |
| Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages. | Toxicological sciences : an official journal of the Society of Toxicology 20050601 |
| Perinatal exposure to low levels of the environmental antiandrogen vinclozolin alters sex-differentiated social play and sexual behaviors in the rat. | Environmental health perspectives 20050601 |
| The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase. | Life sciences 20050520 |
| 5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells. | The Prostate 20050515 |
| Functional genomics may allow accurate categorization of the benzimidazole fungicide benomyl: lack of ability to act via steroid-receptor-mediated mechanisms. | Toxicology and applied pharmacology 20050515 |
| Factors regulating the timing of puberty onset in female rhesus monkeys (Macaca mulatta): role of prenatal androgens, social rank, and adolescent body weight. | Biology of reproduction 20050501 |
| Follicle-stimulating hormone regulates both Sertoli cell and spermatogonial populations in the adult photoinhibited Djungarian hamster testis. | Biology of reproduction 20050501 |
| Androgen regulation of stage-dependent cyclin D2 expression in Sertoli cells suggests a role in modulating androgen action on spermatogenesis. | Biology of reproduction 20050501 |
| Testosterone and autumn territorial behavior in male red grouse Lagopus lagopus scoticus. | Hormones and behavior 20050501 |
| Castration reduces platelet thromboxane A2 receptor density and aggregability. | QJM : monthly journal of the Association of Physicians 20050501 |
| Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens. | Domestic animal endocrinology 20050501 |
| Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development. | Reproduction (Cambridge, England) 20050501 |
| [Establishment of reporter gene-based assays for the identification of (anti) androgenic effects of chemicals in CHO cells]. | Wei sheng yan jiu = Journal of hygiene research 20050501 |
| Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. | Journal of medicinal chemistry 20050421 |
| Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands. | Bioorganic & medicinal chemistry 20050415 |
| Survivin mediates resistance to antiandrogen therapy in prostate cancer. | Oncogene 20050407 |
| Potential estrogenic and antiandrogenic effects of permethrin in rats. | The Journal of reproduction and development 20050401 |
| Androgen-regulated transcripts in the neonatal mouse testis as determined through microarray analysis. | Biology of reproduction 20050401 |
| Organizational role for testosterone and estrogen on adult hypothalamic-pituitary-adrenal axis activity in the male rat. | Endocrinology 20050401 |
| Androgens stimulate human vascular smooth muscle cell proteoglycan biosynthesis and increase lipoprotein binding. | Endocrinology 20050401 |
| Effects of in utero and lactational exposure to flutamide in SD rats: comparison of the effects of administration periods. | Toxicology 20050401 |
| Hormonal influences on sexually differentiated behavior in nonhuman primates. | Frontiers in neuroendocrinology 20050401 |
| In vivo and in vitro exposures of carp and carp tissues to graded concentrations of endocrine disrupting chemicals. | Annals of the New York Academy of Sciences 20050401 |
| Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo. | Brain research. Developmental brain research 20050322 |
| Application of an antiandrogen during pregnancy infantilizes the male offsprings' behaviour. | Behavioural brain research 20050307 |
| The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states. | American journal of physiology. Gastrointestinal and liver physiology 20050301 |
| Androgens and postmeiotic germ cells regulate claudin-11 expression in rat Sertoli cells. | Endocrinology 20050301 |
| Glutathione peroxidase activity in cell cultures from different regions of human epididymis. | Asian journal of andrology 20050301 |
| Reversibility of androgen deprivation therapy in patients with prostate cancer. | The Journal of urology 20050301 |
| Positron tomographic assessment of androgen receptors in prostatic carcinoma. | European journal of nuclear medicine and molecular imaging 20050301 |
| Antihypertensive effects of flutamide in rats that are exposed to a low-protein diet in utero. | American journal of obstetrics and gynecology 20050301 |
| [High intensity focused ultrasound combined with endocrine therapy in treating prostate cancer]. | Zhonghua nan ke xue = National journal of andrology 20050301 |
| [Alfa-blockade with doxazosin vs tamsulozin in combination of intermittent androgen blockade in patients with prostate cancer]. | Georgian medical news 20050301 |
| Combined androgen blockade: the case for bicalutamide. | Clinical prostate cancer 20050301 |
| Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain. | Journal of medicinal chemistry 20050224 |
| Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens. | Toxicology letters 20050215 |
| Influence of gonadal steroids on the glial fibrillary acidic protein-immunoreactive astrocyte population in young rat hippocampus. | Journal of neuroscience research 20050215 |
| Middle-age male mice have increased severity of experimental autoimmune encephalomyelitis and are unresponsive to testosterone therapy. | Journal of immunology (Baltimore, Md. : 1950) 20050215 |
| The influence of androgen deprivation therapy on metabolism in patients with prostate cancer. | The Journal of clinical endocrinology and metabolism 20050201 |
| Antiandrogenic effects in short-term in vivo studies of the fungicide fenarimol. | Toxicology 20050201 |
| Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles. | Steroids 20050201 |
| Effects of the androgen antagonist flutamide and the serotonin reuptake inhibitor citalopram in bulimia nervosa: a placebo-controlled pilot study. | Journal of clinical psychopharmacology 20050201 |
| [Hormonal therapy for prostatic cancer--state of the art]. | Nihon rinsho. Japanese journal of clinical medicine 20050201 |
| [Neoadjuvant hormonal therapy for prostate cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20050201 |
| Gubernacular cell division in different rodent models of cryptorchidism supports indirect androgenic action via the genitofemoral nerve. | Journal of pediatric surgery 20050201 |
| Anemia under androgen deprivation: influence of flutamide, cyproteroneacetate and orchiectomy on the erythropoietin system. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050201 |
| 19-Nortestosterone influences neural stem cell proliferation and neurogenesis in the rat brain. | The European journal of neuroscience 20050201 |
| Coagulopathy, following medical therapy, for carcinoma of the prostate. | Hematology (Amsterdam, Netherlands) 20050201 |
| Chlorambucil and lomustine (CL56) in absolute hormone refractory prostate cancer: re-induction of endocrine sensitivity an unexpected finding. | British journal of cancer 20050117 |
| Role of endogenous testosterone in myocardial proinflammatory and proapoptotic signaling after acute ischemia-reperfusion. | American journal of physiology. Heart and circulatory physiology 20050101 |
| Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of metformin at the start and after more than one year of therapy. | The Journal of clinical endocrinology and metabolism 20050101 |
| Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. | Toxicological sciences : an official journal of the Society of Toxicology 20050101 |
| Marked hyperglycemia after androgen-deprivation therapy for prostate cancer and usefulness of pioglitazone for its treatment. | Metabolism: clinical and experimental 20050101 |
| Homologous up-regulation of androgen receptor expression by androgen in vascular smooth muscle cells. | Hormone research 20050101 |
| A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity. | Toxicology and applied pharmacology 20050101 |
| Evidence that androgens and oestrogens, as well as follicle-stimulating hormone, can alter Sertoli cell number in the neonatal rat. | The Journal of endocrinology 20050101 |
| Stable expression of constitutively-activated STAT3 in benign prostatic epithelial cells changes their phenotype to that resembling malignant cells. | Molecular cancer 20050101 |
| Small cell carcinoma of the prostate with hypercalcemia. | International journal of urology : official journal of the Japanese Urological Association 20050101 |
| Paediatric management of endocrine complications in McCune-Albright syndrome. | Journal of pediatric endocrinology & metabolism : JPEM 20050101 |
| Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats. | BMC pharmacology 20050101 |
| Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line. | Anticancer research 20050101 |
| Impact of hormone therapy on acute radiotherapy toxicity in the treatment of prostate cancer. | Prostate cancer and prostatic diseases 20050101 |
| Mechanisms of ensemble failure of the male gonadal axis in aging. | Journal of endocrinological investigation 20050101 |
| Response of T lymphocyte populations in prostate cancer patients undergoing radiotherapy: influence of neoajuvant total androgen suppression. | Anticancer research 20050101 |
| [Severe acute hepatitis due to flutamide and elevated CA 19.9]. | Gastroenterologia y hepatologia 20050101 |
| Intermittent androgen castration: a biological reality during intermittent treatment in metastatic prostate cancer? | Urologia internationalis 20050101 |
| Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride. | Toxicologic pathology 20050101 |
| Biochemical characterization of the Arctic char (Salvelinus alpinus) ovarian progestin membrane receptor. | Reproductive biology and endocrinology : RB&E 20050101 |
| Pharmacological profile of 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04), a new androgen antagonist with antigonadotropic activity. | Arzneimittel-Forschung 20050101 |
| Microscopic polyangiitis complicated by the development of prostate cancer and flutamide-induced hepatitis. | International urology and nephrology 20050101 |
| Gefitinib (Iressa, ZD1839) and tyrosine kinase inhibitors: the wave of the future in cancer therapy. | Cancer nursing 20050101 |
| [Administration of 1 alpha-OH vitamin D3 and calcium prevents bone mass loss in patients with advanced prostatic carcinoma after orchidectomy treated with complete androgenic blockade]. | Endokrynologia Polska 20050101 |
| Dose-dependent transitions in mechanisms of toxicity: case studies. | Toxicology and applied pharmacology 20041215 |
| Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. | Endocrinology 20041201 |
| Effect of anti-estrogens on the androgen receptor activity and cell proliferation in prostate cancer cells. | Urological research 20041201 |
| Anemia in patients on combined androgen block therapy for prostate cancer. | Asian journal of andrology 20041201 |
| Recent advances in the treatment of juvenile angiofibroma. | Current opinion in otolaryngology & head and neck surgery 20041201 |
| Exogenous testosterone inhibits several forms of male parental behavior and stimulates song in a monogamous songbird: the blue-headed vireo (Vireo solitarius). | Hormones and behavior 20041201 |
| Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen. | Hepatology (Baltimore, Md.) 20041201 |
| Bone mineral density in patients with prostate cancer without bone metastases treated with intermittent androgen suppression. | Urology 20041201 |
| Evaluation of the model anti-androgen flutamide for assessing the mechanistic basis of responses to an androgen in the fathead minnow (Pimephales promelas). | Environmental science & technology 20041201 |
| Combined androgen blockade in the management of advanced prostate cancer: a sensible or ostensible approach. | International journal of urology : official journal of the Japanese Urological Association 20041201 |
| Phosphorylation of p70s6 kinase is implicated in androgen-induced levator ani muscle anabolism in castrated rats. | The Journal of steroid biochemistry and molecular biology 20041201 |
| Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy. | The Journal of toxicological sciences 20041201 |
| Polycystic ovary syndrome. | Clinical evidence 20041201 |
| Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow. | Aquatic toxicology (Amsterdam, Netherlands) 20041118 |
| The combined antiandrogenic effects of five commonly used pesticides. | Toxicology and applied pharmacology 20041115 |
| Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane. | Circulation 20041109 |
| Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera. | Journal of medicinal chemistry 20041104 |
| The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats. | Reproductive toxicology (Elmsford, N.Y.) 20041101 |
| Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041101 |
| Optimization of formulation parameters for the preparation of flutamide liposomes by 3(3) factorial 26-term logit model. | Pharmaceutical development and technology 20041101 |
| Epirubicin carboplatin and 5-fluorouracil (ECarboF) chemotherapy in metastatic hormone refractory prostate cancer. | British journal of cancer 20041018 |
| Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development. | Aquatic toxicology (Amsterdam, Netherlands) 20041018 |
| Endocrine-disrupting activity in carbendazim-induced reproductive and developmental toxicity in rats. | Journal of toxicology and environmental health. Part A 20041008 |
| Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. | Journal of medicinal chemistry 20041007 |
| Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells. | Molecular endocrinology (Baltimore, Md.) 20041001 |
| Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 ('Iressa') induces cell-cycle arrest and inhibits proliferation in prostate cancer cells. | Journal of cellular physiology 20041001 |
| Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells. | The Journal of urology 20041001 |
| Hirsutism and acne in polycystic ovary syndrome. | Best practice & research. Clinical obstetrics & gynaecology 20041001 |
| The mitochondrial-dependent pathway is chronically affected in testicular germ cell death in adult rats exposed in utero to anti-androgens. | The Journal of endocrinology 20041001 |
| [Role of androgens in the renal production of 20-hydroxyeicosatetraenoic acid in spontaneously hypertensive rats]. | Nihon Jinzo Gakkai shi 20041001 |
| Androgen dependent development of a modified anal fin, gonopodium, as a model to understand the mechanism of secondary sexual character expression in vertebrates. | FEBS letters 20040924 |
| Is there a role for chemotherapy in prostate cancer? | British journal of cancer 20040913 |
| Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure. | Endocrinology 20040901 |
| Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder. | Endocrinology 20040901 |
| One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. | Psychoneuroendocrinology 20040901 |
| The effect of combined androgen ablation on the expression of alpha1A-adrenergic receptor in the human prostate. | The Prostate 20040901 |
| Report of a multicenter Canadian phase III randomized trial of 3 months vs. 8 months neoadjuvant androgen deprivation before standard-dose radiotherapy for clinically localized prostate cancer. | International journal of radiation oncology, biology, physics 20040901 |
| Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. | The Journal of clinical endocrinology and metabolism 20040901 |
| Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of early, low-dose flutamide. | The Journal of clinical endocrinology and metabolism 20040901 |
| Combination hormonal therapy: a reassessment within advanced prostate cancer. | Prostate cancer and prostatic diseases 20040901 |
| Interstitial pneumonitis related to flutamide monotherapy for prostate cancer. | International journal of urology : official journal of the Japanese Urological Association 20040901 |
| Monotherapy in advanced prostate cancer: an overview. | Experimental oncology 20040901 |
| [Treatment of spinal and bulbar muscular atrophy]. | No to shinkei = Brain and nerve 20040901 |
| Metformin versus flutamide in the treatment of metabolic consequences of non-obese young women with polycystic ovary syndrome: a randomized prospective study. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040901 |
| Cytochrome P450 CYP1B1 activity in renal cell carcinoma. | British journal of cancer 20040831 |
| 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial. | JAMA 20040818 |
| Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. | The Journal of biological chemistry 20040806 |
| Testosterone-induced coronary vasodilatation occurs via a non-genomic mechanism: evidence of a direct calcium antagonism action. | Clinical science (London, England : 1979) 20040801 |
| Flutamide-metformin plus an oral contraceptive (OC) for young women with polycystic ovary syndrome: switch from third- to fourth-generation OC reduces body adiposity. | Human reproduction (Oxford, England) 20040801 |
| Letter to the Editor; Re: Wirth MP, Weissbach L, Marx F-J, Heckl W, Jellinghaus W, Riedmiller H, Noack B, Hinke A, Froehner M. Prospective randomized trial comparing flutamide as adjuvant treatment versus observation after radical prostatectomy for locally advanced, lymph node-negative prostate cancer. Eur Urol 2004;45:267-70. | European urology 20040801 |
| Osteoporosis and spinal fractures in men with prostate cancer: risk factors and effects of androgen deprivation therapy. | The Journal of urology 20040801 |
| Re: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer. | The Journal of urology 20040801 |
| Combined modality treatment in the management of high-risk prostate cancer. | International journal of radiation oncology, biology, physics 20040801 |
| Intermittent androgen suppression for locally advanced and metastatic prostate cancer: preliminary report of a prospective multicenter study. | Urology 20040801 |
| Evaluation for reliability and feasibility of the draft protocol for the enhanced rat 28-day subacute study (OECD Guideline 407) using androgen antagonist flutamide. | Toxicology 20040715 |
| Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse. | Neuroscience letters 20040715 |
| The synthesis of glycoprotein Po and peripheral myelin protein 22 in sciatic nerve of male rats is modulated by testosterone metabolites. | Brain research. Molecular brain research 20040705 |
| Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles. | Biology of reproduction 20040701 |
| Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay. | Toxicology 20040701 |
| Solid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticles. | Journal of pharmaceutical sciences 20040701 |
| Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty. | The Journal of veterinary medical science 20040701 |
| [Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women]. | Revista medica de Chile 20040701 |
| Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. | British journal of cancer 20040614 |
| Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. | British journal of cancer 20040614 |
| Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040609 |
| Effect of keratinocyte growth factor and activin on cell growth in the human prostatic cancer cell line LNCaP. | World journal of urology 20040601 |
| Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements. | Molecular endocrinology (Baltimore, Md.) 20040601 |
| The characterization and hormonal regulation of kidney androgen-regulated protein (Kap)-luciferase transgenic mice. | Toxicological sciences : an official journal of the Society of Toxicology 20040601 |
| Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signaling in the urogenital sinus. | Toxicological sciences : an official journal of the Society of Toxicology 20040601 |
| Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes. | Reproductive toxicology (Elmsford, N.Y.) 20040601 |
| Androgen receptor blockade in the MPOA or VMN: effects on male sociosexual behaviors. | Physiology & behavior 20040601 |
| Colonic toxicity of administered drugs and chemicals. | The American journal of gastroenterology 20040601 |
| Flutamide or thalidomide? | Nursing 20040601 |
| Divergent roles for estrogens and androgens in the expression of female goat sexual behavior. | Hormones and behavior 20040601 |
| [Liver toxicity associated with flutamide]. | Anales de medicina interna (Madrid, Spain : 1984) 20040601 |
| Cost-effective therapy in patients with idiopathic hirsutism. | Expert review of pharmacoeconomics & outcomes research 20040601 |
| Determination of celecoxib in human plasma by high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20040528 |
| Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives. | Journal of molecular medicine (Berlin, Germany) 20040501 |
| Influence of androgen deprivation therapy on volume of anatomic zones of prostate in patients with prostate cancer using magnetic resonance imaging. | Urology 20040501 |
| The use of flutamide as a single antiandrogen treatment for hormone-refractory prostate cancer. | BJU international 20040501 |
| Medical treatment regimens of hirsutism. | Reproductive biomedicine online 20040501 |
| Testosterone and energy metabolism in the estuarine mysid Neomysis integer (Crustacea: Mysidacea) following exposure to endocrine disruptors. | Environmental toxicology and chemistry 20040501 |
| Is photopatch testing useful in the investigation of photosensitivity due to flutamide? | Contact dermatitis 20040501 |
| Which treatment options should be used in adolescents with polycystic ovary syndrome? | Journal of pediatric endocrinology & metabolism : JPEM 20040501 |
| The selection of hormonal therapy in prostate cancer: who, when, and for how long? | Journal of the National Comprehensive Cancer Network : JNCCN 20040501 |
| Effects of tamoxifen, 17α-ethynylestradiol, flutamide, and methyltestosterone on plasma vitellogenin levels of male and female Japanese medaka (Oryzias latipes). | Environmental toxicology and pharmacology 20040501 |
| Effect of organochlorine pesticides on human androgen receptor activation in vitro. | Toxicology and applied pharmacology 20040415 |
| Fatal acute tumor lysis syndrome, hepatic encephalopathy and flare phenomenon following combined androgen blockade. | The Journal of urology 20040401 |
| Metastatic prostate cancer treated by flutamide versus cyproterone acetate. Final analysis of the 'European Organization for Research and Treatment of Cancer' (EORTC) Protocol 30892. | European urology 20040401 |
| Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data. | International journal of radiation oncology, biology, physics 20040401 |
| Ethinylestradiol-drospirenone, flutamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: opposite effects on adipocytokines and body adiposity. | The Journal of clinical endocrinology and metabolism 20040401 |
| Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions. | The Journal of clinical endocrinology and metabolism 20040401 |
| Changes in fat and lean body mass during androgen-deprivation therapy for prostate cancer. | Urology 20040401 |
| Testosterone promotes apoptotic damage in human renal tubular cells. | Kidney international 20040401 |
| Enterocolic lymphocytic phlebitis with lymphocytic colitis, lymphocytic appendicitis, and lymphocytic enteritis. | The American journal of surgical pathology 20040401 |
| Flutamide as a preoperative treatment in juvenile angiofibroma (JA) with intracranial invasion: report of 7 cases. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20040401 |
| Tissue alterations in the Guinea pig lateral prostate following antiandrogen flutamide therapy. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20040401 |
| Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination. | Journal of endocrinological investigation 20040401 |
| The use of hormonal therapy with radiotherapy for prostate cancer: analysis of prospective randomised trials. | British journal of cancer 20040308 |
| Feedback inhibition of steroidogenic acute regulatory protein expression in vitro and in vivo by androgens. | Endocrinology 20040301 |
| Morphological features of external genitalia in hypospadiac rat model: 3-dimensional analysis. | The Journal of urology 20040301 |
| Regulation of mouse renal CYP2J5 expression by sex hormones. | Molecular pharmacology 20040301 |
| [Recurrent ischemic strokes secondary to acquired hypercoagulability in a patient with prostatic adenocarcinoma]. | Neurologia (Barcelona, Spain) 20040301 |
| [Toxic hepatitis and liver failure under therapy with flutamide]. | Der Internist 20040301 |
| Biochemical remission after resection of prostate cancer lung metastasis. | Urology 20040301 |
| Prospective randomized trial comparing flutamide as adjuvant treatment versus observation after radical prostatectomy for locally advanced, lymph node-negative prostate cancer. | European urology 20040301 |
| [Examination of the change in plasma concentration of OH-flutamide in low-dose flutamide (250 mg/day) monotherapy for prostate cancer patients]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040301 |
| An evaluation of bicalutamide in the treatment of prostate cancer. | Clinical prostate cancer 20040301 |
| [A mouse model of hypospadias induced by flutamide]. | Zhonghua nan ke xue = National journal of andrology 20040301 |
| Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol. | Neuroreport 20040301 |
| Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes. | The Journal of steroid biochemistry and molecular biology 20040301 |
| Toxic hepatitis after sequential administration of flutamide and cyproterone acetate. | Digestive diseases and sciences 20040301 |
| Ectopic expression of the amino-terminal peptide of androgen receptor leads to androgen receptor dysfunction and inhibition of androgen receptor-mediated prostate cancer growth. | Molecular and cellular endocrinology 20040212 |
| Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. | Endocrinology 20040201 |
| Chemohormonal therapy as primary treatment for metastatic prostate cancer: a randomized study of estramustine phosphate plus luteinizing hormone-releasing hormone agonist versus flutamide plus luteinizing hormone-releasing hormone agonist. | International journal of urology : official journal of the Japanese Urological Association 20040201 |
| Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy. | The Journal of urology 20040201 |
| Direct gastrointestinal toxicity of flutamide: comparison of irradiated and nonirradiated cases. | The Journal of urology 20040201 |
| Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome. | Clinical endocrinology 20040201 |
| Antagonists of growth hormone-releasing hormone (GH-RH) enhance tumour growth inhibition induced by androgen deprivation in human MDA-Pca-2b prostate cancers. | European journal of cancer (Oxford, England : 1990) 20040201 |
| Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate. | Journal of clinical pathology 20040201 |
| Tibolone and its metabolites induce antimitogenesis in human coronary artery smooth muscle cells: role of estrogen, progesterone, and androgen receptors. | The Journal of clinical endocrinology and metabolism 20040201 |
| Androgen inhibition of MAP kinase pathway and Elk-1 activation in proliferating osteoblasts. | Journal of molecular endocrinology 20040201 |
| Physiological levels of 5 alpha-dihydrotestosterone depress wound immune function and impair wound healing following trauma-hemorrhage. | Archives of surgery (Chicago, Ill. : 1960) 20040201 |
| The treatment of polycystic ovary syndrome. | Minerva ginecologica 20040201 |
| [The antiandrogenic effect of dimethachlon and its mechanism]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201 |
| Widespread vitiligo after erythroderma caused by photosensitivity to flutamide. | Contact dermatitis 20040201 |
| Effects of the antiandrogen flutamide on the expression of protein kinase C isoenzymes in LNCaP and PC3 human prostate cancer cells. | Bioscience reports 20040201 |
| The effects of combined aromatase inhibitor and anti-androgen on male territorial aggression in a tropical population of rufous-collared sparrows, Zonotrichia capensis. | General and comparative endocrinology 20040115 |
| Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040115 |
| Randomized Phase II trial assessing estramustine and vinblastine combination chemotherapy vs estramustine alone in patients with progressive hormone-escaped metastatic prostate cancer. | British journal of cancer 20040112 |
| Androgen-sensitive changes in regulation of restraint-induced adrenocorticotropin secretion between early and late puberty in male rats. | Endocrinology 20040101 |
| Prognosis of stage pT0 after prolonged neoadjuvant endocrine therapy of prostate cancer: a matched-pair analysis. | European urology 20040101 |
| Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. | The American journal of pathology 20040101 |
| Involvement of serotoninergic mechanism in analgesia by castration and flutamide, a testosterone antagonist, in the rat formalin test. | Pharmacology, biochemistry, and behavior 20040101 |
| Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in rats. | Basic & clinical pharmacology & toxicology 20040101 |
| Antiandrogen monotherapy: recommendations for the treatment of prostate cancer. | Urologia internationalis 20040101 |
| Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures. | Prostate cancer and prostatic diseases 20040101 |
| Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome. | Gynecologic and obstetric investigation 20040101 |
| Male breast adenocarcinoma in a prostate cancer patient following prolonged anti-androgen monotherapy. | Anticancer research 20040101 |
| Chronic effects of flutamide in male beagle dogs. | Toxicologic pathology 20040101 |
| Flutamide administration at 500 mg daily has similar effects on serum testosterone to 750 mg daily. | Journal of andrology 20040101 |
| Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function. | Reproductive toxicology (Elmsford, N.Y.) 20040101 |
| Anogenital distance in human male and female newborns: a descriptive, cross-sectional study. | Environmental health : a global access science source 20040101 |
| Potential action of androstenedione on the proliferation and apoptosis of stromal endometrial cells. | Reproductive biology and endocrinology : RB&E 20040101 |
| Effect of androgens on sexual differentiation of pituitary gamma-aminobutyric acid receptor subunit GABA(B) expression. | Neuroendocrinology 20040101 |
| Hepatotoxicity induced by antiandrogens: a review of the literature. | Urologia internationalis 20040101 |
| Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. | Arzneimittel-Forschung 20040101 |
| [Experience with therapy of prostate cancer in the Primorye Territory]. | Voprosy onkologii 20040101 |
| Development of vitellogenin assay for endocrine disrupters using medaka (Oryzias latipes). | Environmental sciences : an international journal of environmental physiology and toxicology 20040101 |
| Practical approach to the hormonal treatment of acne. | Journal of cutaneous medicine and surgery 20040101 |
| Hormonal treatment of acne: review of current best evidence. | Journal of cutaneous medicine and surgery 20040101 |
| Hormonal therapy of acne. | Journal of cutaneous medicine and surgery 20040101 |
| Estrogen and androgen regulation of plasma membrane calcium pump activity in immortalized distal tubule kidney cells. | Molecular and cellular endocrinology 20031230 |
| Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. | Cancer 20031201 |
| Testosterone decreases the potential for song plasticity in adult male zebra finches. | Hormones and behavior 20031201 |
| Regulatory roles of androgens in cutaneous wound healing. | Thrombosis and haemostasis 20031201 |
| [Progress in researches on drugs for prostate cancer]. | Zhonghua nan ke xue = National journal of andrology 20031201 |
| Antiandrogen-associated hepatotoxicity in the management of advanced prostate cancer. | Journal of the Chinese Medical Association : JCMA 20031201 |
| Clinical strategies in the management of biochemical recurrence after radical prostatectomy. | Clinical prostate cancer 20031201 |
| Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate. | Journal of medicinal chemistry 20031120 |
| Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | British journal of cancer 20031117 |
| The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer. | The Journal of urology 20031101 |
| Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines. | The Journal of urology 20031101 |
| Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group Protocol 92-02. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031101 |
| The use of flutamide as a single antiandrogen treatment for hormone-refractory prostate cancer. | BJU international 20031101 |
| Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy. | Urology 20031101 |
| Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate. | Urology 20031101 |
| Effect of dihydrotestosterone on pituitary follicle-stimulating hormone isoforms in adult male rats treated with a gonadotropin-releasing hormone antagonist. | Neuroendocrinology 20031101 |
| A role for the androgen receptor in the endometrial antiproliferative effects of progesterone antagonists. | Steroids 20031101 |
| Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20031101 |
| Identification and prediction of promiscuous aggregating inhibitors among known drugs. | Journal of medicinal chemistry 20031009 |
| Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis. | Molecular endocrinology (Baltimore, Md.) 20031001 |
| Interactions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose-binding site of the human erythrocyte glucose transporter GLUT1. | British journal of pharmacology 20031001 |
| Long-term outcome of antiandrogen monotherapy in advanced prostate carcinoma: 12-year results of a phase II study. | BJU international 20031001 |
| Metabolite profiles of flutamide in serum from patients with flutamide-induced hepatic dysfunction. | Biological & pharmaceutical bulletin 20031001 |
| Prostate carcinoma presenting as multiple pulmonary nodules in an asymptomatic patient with a history of testicular nonseminomatous germ cell tumor. | Urology 20031001 |
| Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism: effects in adolescents and in women on third-generation oral contraception. | The Journal of clinical endocrinology and metabolism 20031001 |
| Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | Chemical research in toxicology 20031001 |
| Flutamide-induced hepatic dysfunction in relation to steady-state plasma concentrations of flutamide and its metabolites. | Molecular and cellular biochemistry 20031001 |
| [From the gene to the clinic: prostate cancer death can now be an exception?]. | Medecine sciences : M/S 20031001 |
| [Comparative study of the effect of complete prolonged neoadjuvant hormonal blockade versus standard hormonal blockade]. | Actas urologicas espanolas 20031001 |
| Neuroendocrine mechanisms of development of experimental hyperandrogen-induced anovulation. | Neuroscience and behavioral physiology 20031001 |
| Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat. | The Journal of reproduction and development 20031001 |
| In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor. | The Prostate 20030915 |
| Intermittent chemotherapy in metastatic androgen-independent prostate cancer. | British journal of cancer 20030915 |
| Androgen deprivation and cognition in prostate cancer. | British journal of cancer 20030915 |
| Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway. | Oncogene 20030911 |
| Play, copulation, anatomy, and testosterone in gonadally intact male rats prenatally exposed to flutamide. | Physiology & behavior 20030901 |
| Acceptability of short term neo-adjuvant androgen deprivation in patients with locally advanced prostate cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030901 |
| [Anemia in patients on combined androgen block therapy for prostate cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20030901 |
| Alteration of lactate production and transport in the adult rat testis exposed in utero to flutamide. | Molecular and cellular endocrinology 20030829 |
| Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor. | Bioorganic & medicinal chemistry letters 20030818 |
| Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator. | Cancer research 20030815 |
| Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892). | European urology 20030801 |
| Two organizational effects of pubertal testosterone in male rats: transient social memory and a shift away from long-term potentiation following a tetanus in hippocampal CA1. | Experimental neurology 20030801 |
| Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer. | American journal of clinical oncology 20030801 |
| Pneumonitis and non steroidal antiandrogens. | Prescrire international 20030801 |
| Effects of perinatal exposure to flutamide on sex hormone responsiveness in F1 male rats. | The Journal of toxicological sciences 20030801 |
| Comparison of prostate gene expression and tissue weight changes as monitors of antiandrogen activity in GNRH-inhibited rats. | Birth defects research. Part B, Developmental and reproductive toxicology 20030801 |
| Alterations of gene expression in adult male rat testis and pituitary shortly after subacute administration of the antiandrogen flutamide. | The Journal of reproduction and development 20030801 |
| Cell-specific and hormone-regulated expression of gonadotropin-regulated testicular RNA helicase gene (GRTH/Ddx25) resulting from alternative utilization of translation initiation codons in the rat testis. | The Journal of biological chemistry 20030725 |
| Effects of flutamide in the rat testis on the expression of occludin, an integral member of the tight junctions. | Toxicology letters 20030720 |
| Differential expression of the tetracycline-controlled transactivator-driven human CYP1B1 gene in double-transgenic mice is due to androgens: application for detecting androgens and antiandrogens. | Archives of biochemistry and biophysics 20030715 |
| UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay. | Toxicological sciences : an official journal of the Society of Toxicology 20030701 |
| Androgen receptor independent cardiovascular action of the antiandrogen flutamide. | Journal of molecular medicine (Berlin, Germany) 20030701 |
| An environmental antiandrogen, vinclozolin, alters the organization of play behavior. | Physiology & behavior 20030701 |
| Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up. | Urology 20030701 |
| Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030701 |
| Anti-androgen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome. | Journal of endocrinological investigation 20030701 |
| [Treatment of acne with antiandrogens--an evidence-based review]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20030701 |
| Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. | Nature medicine 20030601 |
| [Malignant priapism as a sign of a recurrent prostate cancer. Differential diagnosis of induratio penis plastica]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20030601 |
| Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism. | The Journal of clinical endocrinology and metabolism 20030601 |
| [Therapeutic options for drug induced liver injury: the efficacy of UDCA based on EBM]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20030601 |
| Circulating nitric oxide levels increase after anti-androgen treatment in male-to-female transsexuals. | Journal of endocrinological investigation 20030601 |
| Ten-year survival in patients with metastatic prostate cancer. | Clinical prostate cancer 20030601 |
| Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction. | British journal of cancer 20030519 |
| The study of spatial memory in adult male rats with injection of testosterone enanthate and flutamide into the basolateral nucleus of the amygdala in Morris water maze. | Brain research 20030516 |
| Variation in chromogranin A serum levels during intermittent versus continuous androgen deprivation therapy for prostate adenocarcinoma. | The Prostate 20030515 |
| Effect of the multidrug resistance protein on the transport of the antiandrogen flutamide. | Cancer research 20030515 |
| Rotational 3D-conformal radiation therapy (conformation therapy) combined with hormone therapy for the treatment of stage B2/C prostate cancer in Japanese men. | International journal of radiation oncology, biology, physics 20030501 |
| Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17. | Biological & pharmaceutical bulletin 20030501 |
| The evaluation and management of hirsutism. | Obstetrics and gynecology 20030501 |
| Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors. | Epilepsia 20030501 |
| Endocrine targets in experimental shock. | The Journal of trauma 20030501 |
| [Neuroendocrine differentiation in adenocarcinoma of the prostate with progression of disease during hormonal treatment: a report of two cases]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20030501 |
| Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells. | The Journal of steroid biochemistry and molecular biology 20030501 |
| Sex differences in interest in infants in juvenile rhesus monkeys: relationship to prenatal androgen. | Hormones and behavior 20030501 |
| Bioassay of steroid hormone agonist and antagonist activities of anti-androgens on mammary gland, seminal vesicles and spleen of male mice. | Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030501 |
| Novel yeast bioassay system for detection of androgenic and antiandrogenic compounds. | Toxicology in vitro : an international journal published in association with BIBRA 20030401 |
| Neoadjuvant flutamide monotherapy for locally confined prostate cancer. | International journal of urology : official journal of the Japanese Urological Association 20030401 |
| Estradiol alleviates acinar cell apoptosis and chronic pancreatitis in male Wistar Bonn/Kobori rats. | Pancreas 20030401 |
| Prostate cancer DNA ploidy and response to salvage hormone therapy after radiotherapy with or without short-term total androgen blockade: an analysis of RTOG 8610. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401 |
| Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds. | Environmental health perspectives 20030401 |
| Androgen blockade enhances response to melanoma vaccine. | The Journal of surgical research 20030401 |
| Effects of tributyltin chloride on the reproductive system in pubertal male rats. | Journal of veterinary science 20030401 |
| Mechanisms of vasorelaxation to testosterone in the rat aorta. | European journal of pharmacology 20030328 |
| Androgen regulation of parathyroid hormone-related peptide production in human prostate cancer cells. | Endocrinology 20030301 |
| Effects of androgens on sex differentiation of the urodele Pleurodeles waltl. | Journal of experimental zoology. Part A, Comparative experimental biology 20030301 |
| Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy. | Cancer 20030301 |
| The role of antiandrogen monotherapy in the treatment of prostate cancer. | BJU international 20030301 |
| Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats. | Hypertension (Dallas, Tex. : 1979) 20030301 |
| Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH. | The Journal of endocrinology 20030301 |
| Flutamide-induced photosensitivity: is it a forme fruste of lupus? | The British journal of dermatology 20030301 |
| Microscopic pulmonary tumor embolism secondary to adenocarcinoma of the prostate. | Hinyokika kiyo. Acta urologica Japonica 20030301 |
| SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo. | British journal of cancer 20030210 |
| The effects of anti-androgenic and estrogenic disrupting contaminants on breeding gland (nuptial pad) morphology, plasma testosterone levels, and plasma vitellogenin levels in male Xenopus laevis (African clawed frog). | Archives of environmental contamination and toxicology 20030201 |
| Chronic administration of anabolic steroids disrupts pubertal onset and estrous cyclicity in rats. | Biology of reproduction 20030201 |
| Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide. | Endocrinology 20030201 |
| Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. | Molecular endocrinology (Baltimore, Md.) 20030201 |
| Flutamide counteracts the antiproliferative effects of antiprogestins in the primate endometrium. | The Journal of clinical endocrinology and metabolism 20030201 |
| Collagenous and lymphocytic colitis. evaluation of clinical and histological features, response to treatment, and long-term follow-up. | The American journal of gastroenterology 20030201 |
| Neoadjuvant androgen deprivation and prostate gland shrinkage during conformal radiotherapy. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030201 |
| Percentage of the positive area of bone metastasis is an independent predictor of disease death in advanced prostate cancer. | British journal of cancer 20030127 |
| Metastatic carcinoma of the prostate: identifying prognostic groups using recursive partitioning. | The Journal of urology 20030101 |
| Race and survival of men treated for prostate cancer on radiation therapy oncology group phase III randomized trials. | The Journal of urology 20030101 |
| Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor. | Molecular pharmacology 20030101 |
| Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome. | Cancer research 20030101 |
| Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome. | The Journal of clinical endocrinology and metabolism 20030101 |
| Treatment of hyperandrogenic alopecia in women. | Fertility and sterility 20030101 |
| Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with polycystic ovary syndrome. | Human reproduction (Oxford, England) 20030101 |
| Effects of estrogenic and antiandrogenic compounds on the testis structure of the adult guppy (Poecilia reticulata). | Ecotoxicology and environmental safety 20030101 |
| [First line therapy in the treatment of metastatic prostate cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030101 |
| [Expression of androgen receptor protein in hormone refractory prostate cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20030101 |
| Update and future of systemic acne treatment. | Dermatology (Basel, Switzerland) 20030101 |
| Update and future of hormonal therapy in acne. | Dermatology (Basel, Switzerland) 20030101 |
| [Antigonadotropic effects of a 19-nor-progesterone derivative: the example of nomegestrol acetate]. | Gynecologie, obstetrique & fertilite 20030101 |
| Prognostic significance of changes in short-term prostate volume and serum prostate-specific antigen after androgen withdrawal in men with metastatic prostate cancer. | Urologia internationalis 20030101 |
| Flutamide-induced hepatotoxicity with possible potentiation by simvastatin. | The Journal of the Association of Physicians of India 20030101 |
| Neoadjuvant therapy before radical prostatectomy in high-risk localized prostate cancer: defining appropriate endpoints. | Urologic oncology 20030101 |
| Combined androgen blockade-induced anemia in prostate cancer patients without bone involvement. | Anticancer research 20030101 |
| Androgens, estrogens, and mammary epithelial proliferation. | Menopause (New York, N.Y.) 20030101 |
| A physiologic role for testosterone in limiting estrogenic stimulation of the breast. | Menopause (New York, N.Y.) 20030101 |
| Androgen receptor in prostate carcinoma: immunohistochemical and ligand saturation analyses. | Neoplasma 20030101 |
| Hepatic failure with flutamide. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20030101 |
| Biochemical recurrence of prostate cancer. | Current problems in cancer 20030101 |
| [The hypothalamic-hypophyseal-gonadal system and its functional reserve during long-term vibration and noise]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101 |
| Management of epidural cauda equina disease of prostate cancer by radiotherapy. | Radiation medicine 20030101 |
| Cyproterone acetate for hirsutism. | The Cochrane database of systematic reviews 20030101 |
| Leptin levels increase during flutamide therapy in women with polycystic ovary syndrome. | Hormone research 20030101 |
| Flutamide-associated acute liver failure. | Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20030101 |
| Therapeutic androgen receptor ligands. | Nuclear receptor signaling 20030101 |
| Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats. | Cancer letters 20021201 |
| Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance. | Endocrinology 20021201 |
| Effect of a short course of neoadjuvant hormonal therapy on the response to subsequent androgen suppression in prostate cancer patients with relapse after radiotherapy: a secondary analysis of the randomized protocol RTOG 86-10. | International journal of radiation oncology, biology, physics 20021201 |
| Effect of an anti-androgen on testicular descent and inguinal closure in a marsupial, the tammar wallaby (Macropus eugenii). | Reproduction (Cambridge, England) 20021201 |
| [Antiandrogen in prostate cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20021201 |
| [Total androgen blockade]. | Nihon rinsho. Japanese journal of clinical medicine 20021201 |
| Testosterone suppression in men with prostate cancer is associated with increased arterial stiffness. | The aging male : the official journal of the International Society for the Study of the Aging Male 20021201 |
| Intermittent versus continuous total androgen blockade in the treatment of patients with advanced hormone-naive prostate cancer: results of a prospective randomized multicenter trial. | Clinical prostate cancer 20021201 |
| Effects of hydroxyflutamide in the medial preoptic area or lateral septum on reproductive behaviors in male rats. | Brain research bulletin 20021130 |
| Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells. | Neuroreport 20021115 |
| Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. | British journal of cancer 20021104 |
| Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta. | Biology of reproduction 20021101 |
| Neoadjuvant therapy before radical prostatectomy for clinical T3/T4 carcinoma of the prostate: 5-year followup, Phase II Southwest Oncology Group Study 9109. | The Journal of urology 20021101 |
| Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene. | Journal of the American Society of Nephrology : JASN 20021101 |
| Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells. | Cancer research 20021101 |
| Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer: updated results of a multicentric trial. | European urology 20021101 |
| Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity? | The European journal of neuroscience 20021101 |
| Down-regulation of androgen receptor expression and inhibition of lacrimal gland cell proliferation by retinoic acid. | Experimental eye research 20021101 |
| Regulation of gonadotropin secretion: implications for polycystic ovary syndrome. | Seminars in reproductive medicine 20021101 |
| Effects of 17 alpha-methyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors. | The Journal of steroid biochemistry and molecular biology 20021101 |
| Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating. | Proceedings. Biological sciences 20021007 |
| Sex differences in progesterone receptor expression: a potential mechanism for estradiol-mediated sexual differentiation. | Endocrinology 20021001 |
| Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis. | Biology of reproduction 20021001 |
| Pneumonitis associated with nonsteroidal antiandrogens: presumptive evidence of a class effect. | Annals of internal medicine 20021001 |
| Flutamide induces relaxation in large and small blood vessels. | Archives of surgery (Chicago, Ill. : 1960) 20021001 |
| Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz. | Toxicological sciences : an official journal of the Society of Toxicology 20021001 |
| Neoadjuvant hormonal therapy prior to radical prostatectomy: evaluation of pathological downstaging and biochemical relapse. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20021001 |
| Opposite actions of testosterone and progesterone on UCP1 mRNA expression in cultured brown adipocytes. | Cellular and molecular life sciences : CMLS 20021001 |
| Regulation of the expression of protein kinase C isoenzymes in rat ventral prostate: effects of age, castration and flutamide treatment. | Life sciences 20020927 |
| Phase II study to evaluate combining gemcitabine with flutamide in advanced pancreatic cancer patients. | British journal of cancer 20020923 |
| Ovarian hormones after postnatal day 20 reduce neuron number in the rat primary visual cortex. | Journal of neurobiology 20020915 |
| No androgenic/anti-androgenic effects of bisphenol-A in Hershberger assay using immature castrated rats. | Toxicology letters 20020905 |
| An evaluation of bicalutamide in the treatment of prostate cancer. | Expert opinion on pharmacotherapy 20020901 |
| Impact of previous local treatment for prostate cancer on subsequent metastatic disease. | The Journal of urology 20020901 |
| Pharmacogenomics opportunities in nuclear receptor targeted cancer therapy. | Current cancer drug targets 20020901 |
| Nerve growth factor induces the re-expression of functional androgen receptors and p75(NGFR) in the androgen-insensitive prostate cancer cell line DU145. | European journal of endocrinology 20020901 |
| Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens. | Toxicological sciences : an official journal of the Society of Toxicology 20020901 |
| Antiandrogen monotherapy: indications and results. | Urology 20020901 |
| Androgen receptor as a target in androgen-independent prostate cancer. | Urology 20020901 |
| In vivo modulation of androgen receptor by androgens. | Asian journal of andrology 20020901 |
| Effects of testosterone on neuromuscular transmission in rat isolated urinary bladder. | European journal of pharmacology 20020809 |
| Hormone therapy for locally advanced prostate cancer. | The Journal of urology 20020801 |
| Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus. | Biology of reproduction 20020801 |
| A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women. | Clinical endocrinology 20020801 |
| Prospective randomised trial comparing diethylstilboestrol and flutamide in the treatment of hormone relapsed prostate cancer. | International journal of urology : official journal of the Japanese Urological Association 20020801 |
| [Prostatic cancer with multiple pulmonary metastases treated successfully with hormonal therapy: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20020801 |
| Embryonic myosin heavy chain and troponin T isoforms remain in the cremaster muscle of adult rat cryptorchidism induced with flutamide. | Archives of histology and cytology 20020801 |
| [Sex-difference on flutamide metabolism in rat liver microsomal cytochrome P450 1A2]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020801 |
| Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei. | FEBS letters 20020717 |
| Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat. | Toxicological sciences : an official journal of the Society of Toxicology 20020701 |
| Hormonal therapies in acne. | Expert opinion on pharmacotherapy 20020701 |
| Effect of local heating of rat testes after suppression of spermatogenesis by pretreatment with a GnRH agonist and an anti-androgen. | Reproduction (Cambridge, England) 20020701 |
| Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer? | Urology 20020701 |
| Flutamide decreases cortisol clearance in patients with congenital adrenal hyperplasia. | The Journal of clinical endocrinology and metabolism 20020701 |
| Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
| Stabilization of androgen receptor protein is induced by agonist, not by antagonists. | Biochemical and biophysical research communications 20020621 |
| Androgens protect against apolipoprotein E4-induced cognitive deficits. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615 |
| Changes in bone mineral density, lean body mass and fat content as measured by dual energy x-ray absorptiometry in patients with prostate cancer without apparent bone metastases given androgen deprivation therapy. | The Journal of urology 20020601 |
| Testosterone and estradiol differentially regulate TSH-induced thyrocyte proliferation in immature and adult rats. | Steroids 20020601 |
| Decreased 5alpha-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage. | American journal of physiology. Cell physiology 20020601 |
| Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens. | Biology of reproduction 20020601 |
| Pulmonary vasodilatory action of testosterone: evidence of a calcium antagonistic action. | Journal of cardiovascular pharmacology 20020601 |
| Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation. | The Journal of clinical endocrinology and metabolism 20020601 |
| The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome. | Fertility and sterility 20020601 |
| Assessing meaningful change in quality of life over time: a users' guide for clinicians. | Mayo Clinic proceedings 20020601 |
| Cytotoxicity of flutamide and 2-hydroxyflutamide and their effects on CYP1A2 mRNA in primary rat hepatocytes. | Acta pharmacologica Sinica 20020601 |
| Androgens and environmental antiandrogens affect reproductive development and play behavior in the Sprague-Dawley rat. | Environmental health perspectives 20020601 |
| Novel non-steroidal/non-anilide type androgen antagonists with an isoxazolone moiety. | Bioorganic & medicinal chemistry 20020501 |
| A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer. | Endocrinology 20020501 |
| Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide. | Toxicological sciences : an official journal of the Society of Toxicology 20020501 |
| AR possesses an intrinsic hormone-independent transcriptional activity. | Molecular endocrinology (Baltimore, Md.) 20020501 |
| The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue. | Diabetes, obesity & metabolism 20020501 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020501 |
| [Hirsutism and hypertrichosis in adults: investigations and treatment]. | Annales de dermatologie et de venereologie 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Antiandrogen blocks estrogen-induced masculinization of the song system in female zebra finches. | Journal of neurobiology 20020401 |
| The amino terminus of the human AR is target for corepressor action and antihormone agonism. | Molecular endocrinology (Baltimore, Md.) 20020401 |
| Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide. | European journal of clinical pharmacology 20020401 |
| Treatment with flutamide decreases cortisol clearance: implications for therapy in congenital adrenal hyperplasia. | Journal of pediatric endocrinology & metabolism : JPEM 20020401 |
| [The role of bicalutamide in the treatment of prostate cancer]. | Harefuah 20020401 |
| Concept evaluation: androgen-stimulated immature intact male rats as an assay for antiandrogens. | Regulatory toxicology and pharmacology : RTP 20020401 |
| Stability study of flutamide in solid state and in aqueous solution. | Drug development and industrial pharmacy 20020401 |
| Novel reagents for the sensitive spectrophotometric determination of flutamide, an anticancer drug in pharmaceutical preparations. | International journal of pharmaceutics 20020320 |
| Post-hatching hormonal modulation of a sexually dimorphic neuromuscular system controlling song in zebra finches. | Brain research 20020308 |
| Spermatogenesis, fertility and sexual behavior in a hypospadiac mouse model. | The Journal of urology 20020301 |
| Exposure of juvenile guppies to three antiandrogens causes demasculinization and a reduced sperm count in adult males. | Aquatic toxicology (Amsterdam, Netherlands) 20020301 |
| Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening. | Toxicological sciences : an official journal of the Society of Toxicology 20020301 |
| Anti-androgens for the treatment of hirsutism. | Expert opinion on investigational drugs 20020301 |
| Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model. | Cancer research 20020301 |
| Effect of prenatal androgen receptor antagonist or aromatase inhibitor on sexual behavior, partner preference and neuronal Fos responses to estrous female odors in the rat accessory olfactory system. | Physiology & behavior 20020301 |
| Effects of flutamide on puberty in male rats: an evaluation of the protocol for the assessment of pubertal development and thyroid function. | Journal of toxicology and environmental health. Part A 20020301 |
| The effect of flutamide and tamoxifen on sex hormone-induced mammary carcinogenesis and pituitary adenoma. | Breast cancer research and treatment 20020301 |
| Bone alkaline phosphatase serum level predicts the response to antiandrogen withdrawal. | European urology 20020301 |
| Tibolone and 5alpha-dihydrotestosterone alone or in combination with an antiandrogen in a rat breast tumour model. | European journal of cancer (Oxford, England : 1990) 20020201 |
| Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels. | British journal of pharmacology 20020201 |
| Seasonal differences in the hormonal control of territorial aggression in free-living European stonechats. | Hormones and behavior 20020201 |
| Parental responsiveness is feminized after neonatal castration in virgin male prairie voles, but is not masculinized by perinatal testosterone in virgin females. | Hormones and behavior 20020201 |
| Effects of perinatal exposure to flutamide on sex hormones and androgen-dependent organs in F1 male rats. | The Journal of toxicological sciences 20020201 |
| Low serum testosterone level predicts worse response to endocrine therapy in Japanese patients with metastatic prostate cancer. | Endocrine journal 20020201 |
| Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways. | Brain research. Molecular brain research 20020131 |
| Neoadjuvant androgen ablation before radical prostatectomy in cT2bNxMo prostate cancer: 5-year results. | The Journal of urology 20020101 |
| A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary. | Biology of reproduction 20020101 |
| Dehydroepiandrosterone inhibits human vascular smooth muscle cell proliferation independent of ARs and ERs. | The Journal of clinical endocrinology and metabolism 20020101 |
| Endocrine active agents: implications of adverse and non-adverse changes. | Toxicologic pathology 20020101 |
| Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate. | Reproductive toxicology (Elmsford, N.Y.) 20020101 |
| Clinical utility of ursodeoxycholic acid in preventing flutamide-induced hepatopathy in patients with prostate cancer: a preliminary study. | International journal of urology : official journal of the Japanese Urological Association 20020101 |
| Postorgasmic illness syndrome: two cases. | Journal of sex & marital therapy 20020101 |
| Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis. | Evolution & development 20020101 |
| Tumour cytochrome P450 and drug activation. | Current pharmaceutical design 20020101 |
| Acquired neuroendocrine-positivity during maximal androgen blockade in prostate cancer patients. | Anticancer research 20020101 |
| Flutamide-induced acute renal failure in a patient with metastatic prostate cancer. | Medical oncology (Northwood, London, England) 20020101 |
| Clinical review: immunodepression in the surgical patient and increased susceptibility to infection. | Critical care (London, England) 20020101 |
| Acne: effect of hormones on pathogenesis and management. | American journal of clinical dermatology 20020101 |
| Gender dimorphism in immune responses following trauma and hemorrhage. | Immunologic research 20020101 |
| Caffeine test in predicting flutamide-induced hepatic injury in patients with prostate cancer. | Prostate cancer and prostatic diseases 20020101 |
| Hydroxypropyl-beta-cyclodextrin-flutamide inclusion complex. II. Oral and intravenous pharmacokinetics of flutamide in the rat. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101 |
| Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism. | Gynecologic and obstetric investigation 20020101 |
| Hormono-radiotherapy in prostatic carcinoma: prognostic factors and implications for combined modality treatment. | Tumori 20020101 |
| Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5. | Scandinavian journal of urology and nephrology 20020101 |
| Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss. | Prostate cancer and prostatic diseases 20020101 |
| Preliminary toxicity and prostate-specific antigen response of a Phase I/II trial of neoadjuvant hormonal therapy, 103Pd brachytherapy, and three-dimensional conformal external beam irradiation in the treatment of locally advanced prostate cancer. | Brachytherapy 20020101 |
| Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate. | Toxicological sciences : an official journal of the Society of Toxicology 20011201 |
| Nilutamide: possible utility as a second-line hormonal agent. | Urology 20011201 |
| Relationship between expression of sex steroid receptors and structure of the seminal vesicles after neonatal treatment of rats with potent or weak estrogens. | Environmental health perspectives 20011201 |
| [Hepatotoxicity due to flutamide]. | Atencion primaria 20011115 |
| Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report. | International journal of radiation oncology, biology, physics 20011101 |
| Tamoxifen is an acute, estrogen-like, coronary vasodilator of porcine coronary arteries in vitro. | Journal of cardiovascular pharmacology 20011101 |
| Testosterone and prostate specific antigen stimulate generation of reactive oxygen species in prostate cancer cells. | Carcinogenesis 20011101 |
| Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone. | Kidney international 20011101 |
| Regulation of u-PA gene expression in human prostate cancer. | International journal of cancer 20011101 |
| [A male case of primary bilateral breast cancers during estrogen therapy for prostate cancer]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20011101 |
| Attenuation of vascular endothelial dysfunction by testosterone receptor blockade after trauma and hemorrhagic shock. | Archives of surgery (Chicago, Ill. : 1960) 20011001 |
| Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay. | Regulatory toxicology and pharmacology : RTP 20011001 |
| Antiandrogenic pesticides disrupt sexual characteristics in the adult male guppy Poecilia reticulata. | Environmental health perspectives 20011001 |
| Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011001 |
| The antiosteoporotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade: a double blind, randomized, placebo-controlled crossover study. | Cancer 20010915 |
| Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells. | Journal of the National Cancer Institute 20010905 |
| Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice. | Toxicological sciences : an official journal of the Society of Toxicology 20010901 |
| Flutamide-induced acute hepatitis in advanced prostate cancer patients. | International journal of clinical pharmacology and therapeutics 20010901 |
| Testosterone-secreting gonadotropin-responsive adrenal adenoma and its treatment with the antiandrogen flutamide. | Journal of endocrinological investigation 20010901 |
| [Local staging with magnetic resonance imaging after neoadjuvant hormonal therapy for prostate cancer]. | Hinyokika kiyo. Acta urologica Japonica 20010901 |
| Determination of 2-hydroxyflutamide in human plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. | Journal of chromatography. B, Biomedical sciences and applications 20010805 |
| Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues. | Toxicological sciences : an official journal of the Society of Toxicology 20010801 |
| Randomized comparative study of 3 versus 8-month neoadjuvant hormonal therapy before radical prostatectomy: biochemical and pathological effects. | The Journal of urology 20010801 |
| Prospective evaluation of hot flashes during treatment with parenteral estrogen or complete androgen ablation for metastatic carcinoma of the prostate. | The Journal of urology 20010801 |
| Regulation of keratinocyte growth factor receptor and androgen receptor in epithelial cells of the human prostate. | The Journal of urology 20010801 |
| Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd ) mice. | Biology of reproduction 20010801 |
| Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate. | International journal of radiation oncology, biology, physics 20010801 |
| Antiandrogen monotherapy: a new form of treatment for patients with prostate cancer. | Urology 20010801 |
| Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer. | Urology 20010801 |
| Androgen-induced up-regulation of tubulin isoforms in neuroblastoma cells. | Journal of neurochemistry 20010801 |
| The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein. | The Journal of biological chemistry 20010727 |
| Kap promoter analysis in vivo: a regulatory role for a truncated L1 repeat. | Molecular and cellular endocrinology 20010705 |
| Virilization of the urogenital sinus of the tammar wallaby is not unique to 5alpha-androstane-3alpha,17beta-diol. | Molecular and cellular endocrinology 20010705 |
| Testosterone inhibits spermatogonial differentiation in juvenile spermatogonial depletion mice. | Endocrinology 20010701 |
| M1 prostate cancer with a serum level of prostate-specific antigen less than 10 ng/mL. | International journal of urology : official journal of the Japanese Urological Association 20010701 |
| Flutamide-induced hepatotoxicity: report of a case series. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20010701 |
| Why phase III trials of maximal androgen blockade versus castration in M1 prostate cancer rarely show statistically significant differences. | The Prostate 20010615 |
| Modulation of gene expression by androgen and oestrogens in the testis and prostate of the adult rat following androgen withdrawal. | Molecular and cellular endocrinology 20010610 |
| Steroid-sensitive gene-1 is an androgen-regulated gene expressed in prostatic smooth muscle cells in vivo. | Journal of molecular endocrinology 20010601 |
| Developmental and hormonal regulation of type II DNA topoisomerase in rat testis. | Journal of molecular endocrinology 20010601 |
| Sex differences in infant rhesus macaque separation-rejection vocalizations and effects of prenatal androgens. | Hormones and behavior 20010601 |
| Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons. | Journal of neurochemistry 20010601 |
| Quantification of antiandrogen effect determined by Lightcycler technology. | Toxicology 20010528 |
| Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands. | Journal of medicinal chemistry 20010524 |
| Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen. | Toxicology 20010511 |
| Dissection and weighing of accessory sex glands after formalin fixation, and a 5-day assay using young mature rats are reliable and feasible in the Hershberger assay. | Toxicology 20010511 |
| Chemical andropause and amyloid-beta peptide. | JAMA 20010502 |
| Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia. | American journal of physiology. Cell physiology 20010501 |
| Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells. | The Journal of endocrinology 20010501 |
| Testosterone receptor blockade restores cellular immunity in male mice after burn injury. | The Journal of endocrinology 20010501 |
| Effects of acute stanozolol treatment on puberty in female rats. | Biology of reproduction 20010501 |
| Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27. | Molecular endocrinology (Baltimore, Md.) 20010501 |
| A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma. | Digestive diseases and sciences 20010501 |
| [Complete remission of brain metastases from prostate cancer by gamma knife radiosurgery: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20010501 |
| Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells. | Biochemical and biophysical research communications 20010427 |
| Appropriate column configurations for the rapid analysis and semipreparative purification of the radiolabeled drug flutamide by high-performance liquid chromatography. | Journal of chromatography. A 20010420 |
| The effects of intrahippocampal testosterone and flutamide on spatial localization in the Morris water maze. | Brain research 20010406 |
| Sodium-induced rise in blood pressure is suppressed by androgen receptor blockade. | American journal of physiology. Heart and circulatory physiology 20010401 |
| Chemoprevention for prostatic carcinoma: The role of flutamide in patients with prostatic intraepithelial neoplasia. | Urology 20010401 |
| Combined androgen blockade with nonsteroidal antiandrogens for advanced prostate cancer: a systematic review. | Urology 20010401 |
| [Hirsutism, flutamide and hepatotoxicity]. | Gastroenterologia y hepatologia 20010401 |
| Feasibility and potential gains of enhancing the subacute rat study protocol (OECD test guideline no. 407) by additional parameters selected to determine endocrine modulation. A pre-validation study to determine endocrine-mediated effects of the antiandrogenic drug flutamide. | Archives of toxicology 20010401 |
| [Predicting long-term survival, and the need for hormonal therapy: a meta-analysis of RTOG prostate cancer trials]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20010401 |
| [Clinical efficacy of treatment with low-dose flutamide in maximum androgen blockade therapy]. | Hinyokika kiyo. Acta urologica Japonica 20010401 |
| [What is the role of hormonal treatments in acne?]. | Annales de dermatologie et de venereologie 20010401 |
| [Adenocarcinoma of prostate in men younger than 50--rectal palpation mandatory with micturition problems]. | Nederlands tijdschrift voor geneeskunde 20010324 |
| Administration of tamoxifen but not flutamide to hormonally intact, adult male rats mimics the effects of short-term gonadectomy on the catecholamine innervation of the cerebral cortex. | The Journal of comparative neurology 20010319 |
| Subset analysis of RTOG 85-31 and 86-10 indicates an advantage for long-term vs. short-term adjuvant hormones for patients with locally advanced nonmetastatic prostate cancer treated with radiation therapy. | International journal of radiation oncology, biology, physics 20010315 |
| Androgen receptor antagonism by the organophosphate insecticide fenitrothion. | Toxicological sciences : an official journal of the Society of Toxicology 20010301 |
| Testosterone perturbs epidermal permeability barrier homeostasis. | The Journal of investigative dermatology 20010301 |
| [Long-term survival of hormone-refractory prostate cancer: a case report]. | Journal of UOEH 20010301 |
| The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide. | Pediatric surgery international 20010301 |
| Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism. | Brain research 20010223 |
| Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor. | FEBS letters 20010223 |
| Association of African-American ethnic background with survival in men with metastatic prostate cancer. | Journal of the National Cancer Institute 20010207 |
| Human CYP1B1 and anticancer agent metabolism: mechanism for tumor-specific drug inactivation? | The Journal of pharmacology and experimental therapeutics 20010201 |
| [Anemia and neoadjuvant hormone therapy in radical surgery of localized cancer of the prostate]. | Actas urologicas espanolas 20010201 |
| Inhibition of PSA flare in prostate cancer patients by administration of flutamide for 2 weeks before initiation of treatment with slow-releasing LH-RH agonist. | International journal of clinical oncology 20010201 |
| Sexual dimorphism and aromatase in the rat retina. | Brain research. Developmental brain research 20010131 |
| Nonsteroidal antiandrogens: a therapeutic option for patients with advanced prostate cancer who wish to retain sexual interest and function. | BJU international 20010101 |
| Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice. | American journal of physiology. Renal physiology 20010101 |
| Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: a phase III study of the European organization for research and treatment of cancer genitourinary group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010101 |
| Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. | Molecular endocrinology (Baltimore, Md.) 20010101 |
| Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy. | Journal of bone and mineral metabolism 20010101 |
| Lack of methemoglobinemia with flutamide. | The Annals of pharmacotherapy 20010101 |
| The photochemistry of flutamide and its inclusion complex with beta-cyclodextrin. Dramatic effect of the microenvironment on the nature and on the efficiency of the photodegradation pathways. | Photochemistry and photobiology 20010101 |
| An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance. | Bioelectrochemistry (Amsterdam, Netherlands) 20010101 |
| Hormonal regulation of appetite and body mass in patients with advanced prostate cancer treated with combined androgen blockade. | Journal of endocrinological investigation 20010101 |
| Suppression of androgen action and the induction of gross abnormalities of the reproductive tract in male rats treated neonatally with diethylstilbestrol. | Journal of andrology 20010101 |
| [Suppressive effects of the antiandrogen flutamide on adrenal androgens in advanced prostate cancer patients]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20010101 |
| [Successful complete androgen blockade (CAB) therapy for prostatic cancer detected from multiple lung metastases: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20010101 |
| Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients. | The oncologist 20010101 |
| Optimal starting time for flutamide to prevent disease flare in prostate cancer patients treated with a gonadotropin-releasing hormone agonist. | Urologia internationalis 20010101 |
| A risk-benefit assessment of pharmacological therapies for hirsutism. | Drug safety 20010101 |
| Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats. | Cells, tissues, organs 20010101 |
| Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth. | Reproductive toxicology (Elmsford, N.Y.) 20010101 |
| Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man. | Human reproduction update 20010101 |
| Possible androgenic/anti-androgenic activity of the insecticide fenitrothion. | Journal of applied toxicology : JAT 20010101 |
| Androgen-induced cell growth and c-myc expression in human non-transformed epithelial prostatic cells in primary culture. | Endocrine research 20010101 |
| Strain sensitivity differences in the Hershberger assay. | Reproductive toxicology (Elmsford, N.Y.) 20010101 |
| The role of androgens in mammary carcinogenesis. | Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 20010101 |
| Testosterone and estradiol have specific differential modulatory effect on the proliferation of human thyroid papillary and follicular carcinoma cell lines independent of TSH action. | Endocrine pathology 20010101 |
| Structure toxicity relationships--how useful are they in predicting toxicities of new drugs? | Advances in experimental medicine and biology 20010101 |
| Manipulation of prenatal hormones and dietary phytoestrogens during adulthood alter the sexually dimorphic expression of visual spatial memory. | BMC neuroscience 20010101 |
| Low-dose flutamide (125 mg/day) as maintenance therapy in the treatment of hirsutism. | Hormone research 20010101 |
| Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2 prostate cancer patients. | Anticancer research 20010101 |
| [Nucleic acid and protein content in rat prostate during combined treatment with the gonadorelin agonist and an androgen receptor inhibitor]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101 |
| The effects of GnRH analogues and antiandrogenes in preventing the gonadotoxic effects of COPP chemotherapy. | International urology and nephrology 20010101 |
| Androgen deprivation and other treatments for advanced prostate cancer. | Reviews in urology 20010101 |
| New approaches to the treatment of advanced prostate cancer. | Reviews in urology 20010101 |
| Flare Associated with LHRH-Agonist Therapy. | Reviews in urology 20010101 |
| Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer. | Cancer research 20001201 |
| Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20001201 |
| Antiandrogen withdrawal syndrome associated with prostate cancer therapies: incidence and clinical significance. | Drug safety 20001101 |
| Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat. | Toxicology and applied pharmacology 20000901 |
| The role of estrogen receptor, androgen receptor and growth factors in diethylstilbestrol-induced programming of prostate differentiation. | Urological research 20000801 |
| [Fulminant liver failure induced by flutamide]. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20000601 |
| [Toxic hepatitis caused by flutamide and hirsutism]. | Gastroenterologia y hepatologia 20000501 |
| Effects of an environmental anti-androgen on erectile function in an animal penile erection model. | The Journal of urology 20000401 |
| Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes. | Pharmacology & toxicology 20000301 |
| Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20000201 |
| Prostate cancer treated by anti-androgens: is sexual function preserved? EORTC Genitourinary Group. European Organization for Research and Treatment of Cancer. | British journal of cancer 20000101 |
| Gender differences in hypertension in spontaneously hypertensive rats: role of androgens and androgen receptor. | Hypertension (Dallas, Tex. : 1979) 19991001 |
| Regulation of GCDFP-15 expression in human mammary cancer cells. | International journal of molecular medicine 19990801 |
| [Risk factor of liver disorders caused by flutamide--statistical analysis using multivariate logistic regression analysis]. | Hinyokika kiyo. Acta urologica Japonica 19990801 |
| [Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT]. | Gan to kagaku ryoho. Cancer & chemotherapy 19990701 |
| [Fatal hepatic failure following hepatitis caused by flutamide: a case report]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19990501 |
| [Acute flutamide-induced hepatitis]. | Gastroenterologia y hepatologia 19990501 |
| Fulminant liver failure associated with flutamide therapy for hirsutism. | Lancet (London, England) 19990320 |
| Frequency of flutamide induced hepatotoxicity in patients with prostate carcinoma. | Human & experimental toxicology 19990301 |
| Anaemia in men receiving combined finasteride and flutamide therapy for advanced prostate cancer. | BJU international 19990101 |
| [Toxic hepatitis caused by flutamide]. | Gastroenterologia y hepatologia 19981201 |
| Application of an androgen receptor assay for the characterisation of the androgenic or antiandrogenic activity of various phenylurea herbicides and their derivatives. | The Analyst 19981201 |
| [Ischemic colitis after taking flutamide]. | Gastroenterologie clinique et biologique 19981001 |
| Several environmental oestrogens are also anti-androgens. | The Journal of endocrinology 19980901 |
| Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. | Toxicology and applied pharmacology 19980701 |
| Flutamide-induced acute hepatitis: investigation on the role of immunoallergic mechanisms. | Italian journal of gastroenterology and hepatology 19980601 |
| [Acute cholestatic hepatitis secondary to flutamide]. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 19980501 |
| [The hepatotoxicity of flutamide]. | Klinicheskaia meditsina 19980101 |
| [A case of fulminant hepatitis caused by antiandrogen, flutamide in a patient with prostate cancer]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19970701 |
| Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parameters. | Urology 19970401 |
| Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. | Toxicology and applied pharmacology 19970301 |
| [Liver failure caused by flutamide]. | Actas urologicas espanolas 19970301 |
| [Fulminant liver failure with a fatal outcome due to flutamide]. | Medicina clinica 19970215 |
| Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism. | Toxicology and applied pharmacology 19970101 |
| Non-steroidal L-245,976 acts as a classical antiandrogen in vitro. | The Journal of steroid biochemistry and molecular biology 19970101 |
| Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis. | Digestive diseases and sciences 19961101 |
| Double-blind, randomized study of primary hormonal treatment of stage D2 prostate carcinoma: flutamide versus diethylstilbestrol. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19960801 |
| A case of flutamide-induced acute cholestatic hepatitis--a case report. | Yonsei medical journal 19960601 |
| [Fulminant hepatitis caused by flutamide]. | Gastroenterologie clinique et biologique 19960201 |
| [Hepatic encephalopathy induced by flutamide administered for the treatment of prostatic cancer]. | Journal d'urologie 19960101 |
| [Effects of androgen regulation system on bladder carcinogenesis in male mice]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19951101 |
| Hepatic insufficiency developing as a result of flutamide treatment. | The American journal of gastroenterology 19950601 |
| Use of flutamide for self-induced androgen excess. A case report. | The Journal of reproductive medicine 19941001 |
| Fulminant hepatitis after flutamide treatment. | Journal of hepatology 19940301 |
| Cholestatic hepatitis following flutamide. | Digestive diseases and sciences 19930901 |
| Treatment of advanced prostate cancer with the combination of finasteride plus flutamide: early results. | European urology 19930101 |
| [Acute hepatitis caused by flutamide]. | Presse medicale (Paris, France : 1983) 19910928 |
| Flutamide-induced liver failure. | Journal of hepatology 19900501 |
| Is there a role for pure antiandrogens in the treatment of advanced prostatic cancer? | Progress in clinical and biological research 19900101 |
| [A case of acute hepatitis caused by flutamide]. | Gastroenterologie clinique et biologique 19900101 |
| Flutamide and hepatitis. | Annals of internal medicine 19890601 |
| [Severe toxic hepatitis during flutamide (Eulexin) treatment]. | Ugeskrift for laeger 19890116 |
| Sexuality changes in prostate cancer patients receiving antihormonal therapy combining the antiandrogen flutamide with medical (LHRH agonist) or surgical castration. | Archives of sexual behavior 19880201 |
| The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment. | European journal of clinical pharmacology 19880101 |
| Manic-like episode following flutamide treatment. | The American journal of psychiatry 19861101 |
| Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17. | Molecular endocrinology (Baltimore, Md.) |
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