200,000+ products from a single source!
sales@angenechem.com
133081-24-0 | 3-Pyridinecarboxylic acid, 6-hydrazinyl-
CAS No: 133081-24-0 Catalog No: AG001480 MDL No:MFCD03788692
Product Description
Catalog Number:
AG001480
Chemical Name:
3-Pyridinecarboxylic acid, 6-hydrazinyl-
CAS Number:
133081-24-0
Molecular Formula:
C6H7N3O2
Molecular Weight:
153.1387
MDL Number:
MFCD03788692
IUPAC Name:
6-hydrazinylpyridine-3-carboxylic acid
InChI:
InChI=1S/C6H7N3O2/c7-9-5-2-1-4(3-8-5)6(10)11/h1-3H,7H2,(H,8,9)(H,10,11)
InChI Key:
HBBSDZXXUIHKJE-UHFFFAOYSA-N
SMILES:
NNc1ccc(cn1)C(=O)O
Properties
Complexity:
151
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
153.054g/mol
Formal Charge:
0
Heavy Atom Count:
11
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
153.141g/mol
Monoisotopic Mass:
153.054g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
88.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.3
Literature
| Title | Journal |
|---|---|
| 6-Hydrazinylnicotinic acid: a powder study. | Acta crystallographica. Section E, Structure reports online 20120301 |
| Synthesis and evaluation of analogues of HYNIC as bifunctional chelators for technetium. | Dalton transactions (Cambridge, England : 2003) 20110621 |
| Preparation of catalytically active, covalent α-polylysine-enzyme conjugates via UV/vis-quantifiable bis-aryl hydrazone bond formation. | Biomacromolecules 20110110 |
| Neurotensin(8-13) analogue: radiolabeling and biological evaluation using different chelators. | Nuclear medicine and biology 20110101 |
| Tissue factor detection for selectively discriminating unstable plaques in an atherosclerotic rabbit model. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101201 |
| Imaging with radiolabelled anti-membrane type 1 matrix metalloproteinase (MT1-MMP) antibody: potentials for characterizing atherosclerotic plaques. | European journal of nuclear medicine and molecular imaging 20101101 |
| Gd-EDDA/HYNIC-RGD as an MR molecular probe imaging integrin alphanubeta3 receptor-expressed tumor-MR molecular imaging of angiogenesis. | European journal of radiology 20100201 |
| Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma. | PloS one 20100101 |
| Radiolabeled humanized anti-CD3 monoclonal antibody visilizumab for imaging human T-lymphocytes. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091001 |
| Development of a radiolabeled probe for detecting membrane type-1 matrix metalloproteinase on malignant tumors. | Biological & pharmaceutical bulletin 20090701 |
| Clinical evaluation of antimicrobial peptide [(99m)Tc/Tricine/HYNIC(0)]ubiquicidin 29-41 as a human-specific infection imaging agent. | Nuclear medicine and biology 20090201 |
| Targeting of lectinlike oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti-LOX-1 antibody: potential agent for imaging of vulnerable plaque. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20081001 |
| Breast tumor targeting with (99m)Tc-HYNIC-PR81 complex as a new biologic radiopharmaceutical. | Nuclear medicine and biology 20081001 |
| 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080801 |
| Radiolabeling of annexin A5 with (99m)Tc: comparison of HYNIC-Tc vs. iminothiolane-Tc-tricarbonyl conjugates. | Nuclear medicine and biology 20080801 |
| Initial direct comparison of 99mTc-TOC and 99mTc-TATE in identifying sites of disease in patients with proven GEP NETs. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080701 |
| A technetium intermediate specifically promotes deprotection of trifluoroacetyl HYNIC during radiolabelling under mild conditions. | Dalton transactions (Cambridge, England : 2003) 20080614 |
| Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method. | Proteome science 20080101 |
| Monitoring the protective effects of minocycline treatment with radiolabeled annexin V in an experimental model of focal cerebral ischemia. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071101 |
| Two peptide receptor ligands (99m)Tc-EDDA/HYNIC-Tyr(3)-octreotide and (99m)Tc-EDDA/HYNIC-(D)Glu-octagastrin for scintigraphy of medullary thyroid carcinoma. | Cancer biotherapy & radiopharmaceuticals 20071001 |
| Preclinical evaluation of [99mTc/EDDA/tricine/HYNIC0, 1-Nal3, Thr8]-octreotide as a new analogue in the detection of somatostatin-receptor-positive tumors. | Nuclear medicine and biology 20070801 |
| Confirmation of hydrazone formation in HYNIC-peptide conjugate preparation, and its hydrolysis during labeling with (99m)Tc. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070701 |
| Technetium-99m-labeling and synthesis of thymidine analogs: potential candidates for tumor imaging. | Bioorganic & medicinal chemistry letters 20070615 |
| Labeling biomolecules with radiorhenium: a review of the bifunctional chelators. | Anti-cancer agents in medicinal chemistry 20070501 |
| Trifluoroacetyl-HYNIC peptides: synthesis and 99mTc radiolabeling. | Journal of medicinal chemistry 20070322 |
| 99mTc-EDDA/HYNIC-octreotate in detection of atypical bronchial carcinoid. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070101 |
| Synthesis of oxytocin HYNIC derivatives as potential diagnostic agents for breast cancer. | Bioconjugate chemistry 20070101 |
| Labelling of the anti-III-neurotubulin monoclonal antibody by 99mTc and its binding to responsible antigen. | Nuclear medicine review. Central & Eastern Europe 20070101 |
| The effect of Tc-99m-labeled MDM2 antisense oligonucleotide on gene expression in human breast cancer MCF-7 cells. | Journal of experimental therapeutics & oncology 20070101 |
| Development of a novel 99mTc-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061201 |
| [99mTc]HYNIC-RGD for imaging integrin alphavbeta3 expression. | Nuclear medicine and biology 20061101 |
| An improved method of 18F peptide labeling: hydrazone formation with HYNIC-conjugated c(RGDyK). | Nuclear medicine and biology 20060701 |
| Annexin V SPECT imaging of phosphatidylserine expression in patients with dementia. | Neurology 20060425 |
| Radiolabeled melanin-binding peptides are safe and effective in treatment of human pigmented melanoma in a mouse model of disease. | Cancer biotherapy & radiopharmaceuticals 20060401 |
| Chemoselective hydrazone formation between HYNIC-functionalized peptides and (18)F-fluorinated aldehydes. | Nuclear medicine and biology 20060201 |
| A novel ternary ligand system useful for preparation of cationic (99m)Tc-diazenido complexes and (99m)Tc-labeling of small biomolecules. | Bioconjugate chemistry 20060101 |
| Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci. | Journal of medicinal chemistry 20051006 |
| Evaluation of [99mTc/EDDA/HYNIC0]octreotide derivatives compared with [111In-DOTA0,Tyr3, Thr8]octreotide and [111In-DTPA0]octreotide: does tumor or pancreas uptake correlate with the rate of internalization? | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050901 |
| [99mTc] HYNIC-hEGF, a potential agent for imaging of EGF receptors in vivo: preparation and pre-clinical evaluation. | Oncology reports 20050601 |
| Annexin A5 scintigraphy of forearm as a novel in vivo model of skeletal muscle preconditioning in humans. | Circulation 20050118 |
| 99mTc-labeled mannosyl-neoglycoalbumin for sentinel lymph node identification. | Nuclear medicine and biology 20041001 |
| Intratumoral injection of 188Re labeled cationic polyethylenimine conjugates: a preliminary report. | Journal of Korean medical science 20041001 |
| Intraobserver, interobserver, and day-to-day reproducibility of quantitative 99mTc-HYNIC annexin-V imaging in head and neck carcinoma. | Cancer biotherapy & radiopharmaceuticals 20040401 |
| 99mTc-Hynic-Annexin V. North American Scientific. | IDrugs : the investigational drugs journal 20040301 |
| 99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin. | Bioconjugate chemistry 20040101 |
| Lys and Arg in UBI: a specific site for a stable Tc-99m complex? | Nuclear medicine and biology 20030801 |
| Solid-phase synthesis of peptide radiopharmaceuticals using Fmoc-N-epsilon-(hynic-Boc)-lysine, a technetium-binding amino acid: application to Tc-99m-labeled salmon calcitonin. | Journal of medicinal chemistry 20030424 |
| In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands. | Nuclear medicine and biology 20030201 |
| Phosphine-containing HYNIC derivatives as potential bifunctional chelators for (99m)Tc-labeling of small biomolecules. | Bioconjugate chemistry 20030101 |
| Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide. | Nuclear medicine and biology 20020101 |
| Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes. | Bioconjugate chemistry 20020101 |
| In vitro and in vivo evaluation of a Technetium-99m-labeled cyclic RGD peptide as a specific marker of alpha(V)beta(3) integrin for tumor imaging. | Bioconjugate chemistry 20020101 |
| Specific and rapid scintigraphic detection of infection with 99mTc-labeled interleukin-8. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.