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132472-31-2

132472-31-2 | 3-Heptenoic acid, 2-amino-4-(phosphonomethyl)-, (3E)-

CAS No: 132472-31-2 Catalog No: AG0010Q1 MDL No:

Product Description

Catalog Number:
AG0010Q1
Chemical Name:
3-Heptenoic acid, 2-amino-4-(phosphonomethyl)-, (3E)-
CAS Number:
132472-31-2
Molecular Formula:
C8H16NO5P
Molecular Weight:
237.1901
IUPAC Name:
2-amino-4-(phosphonomethyl)hept-3-enoic acid
InChI:
InChI=1S/C8H16NO5P/c1-2-3-6(5-15(12,13)14)4-7(9)8(10)11/h4,7H,2-3,5,9H2,1H3,(H,10,11)(H2,12,13,14)
InChI Key:
ZEFQYTSQDVUMEU-UHFFFAOYSA-N
SMILES:
CCC/C(=C\C(C(=O)O)N)/CP(=O)(O)O

Properties

Complexity:
295  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
237.077g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
237.192g/mol
Monoisotopic Mass:
237.077g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
121A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
1  
XLogP3:
-3.1  

Literature

Title Journal
Histamine potentiates N-methyl-D-aspartate receptors by interacting with an allosteric site distinct from the polyamine binding site. The Journal of pharmacology and experimental therapeutics 20100301
Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation. Synapse (New York, N.Y.) 20091001
The effect of extracts of Searsia species on epileptiform activity in slices of the mouse cerebral cortex. Journal of ethnopharmacology 20081028
Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070901
Cortical glutamatergic markers in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050801
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. European journal of pharmacology 20040919
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents. Brain research 20040709
A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors. Organic & biomolecular chemistry 20040121
Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain pathology (Zurich, Switzerland) 20031001
Further characterization of the molecular interaction between PSD-95 and NMDA receptors: the effect of the NR1 splice variant and evidence for modulation of channel gating. Journal of neurochemistry 20020601
NMDA receptor involvement in imipramine withdrawal-associated effects on swim stress, GABA levels and NMDA receptor binding in rat hippocampus. Life sciences 20020524
Effect of tributyltin on the N-methyl-D-aspartate (NMDA) receptors in the mouse brain. Archives of toxicology 20011101
Ontogeny of ionotropic glutamate receptor expression in human fetal brain. Brain research. Developmental brain research 20010430
Allosteric modulation of [3H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain. British journal of pharmacology 20010401
Inorganic iron complexes derived from the nitric oxide donor nitroprusside: competitive N-methyl-D-aspartate receptor antagonists with nanomolar affinity. Biochemical pharmacology 20010201
Antinociceptive effects after intrathecal administration of phosphodiester-, 2'-O-allyl-, and C-5-propyne-modified antisense oligodeoxynucleotides targeting the NMDAR1 subunit in mouse. Brain research. Molecular brain research 20010131
Isolation and characterization of histogranin, a natural peptide with NMDA receptor antagonist activity. European journal of pharmacology 19930515

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