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132-32-1

132-32-1 | 9H-Carbazol-3-amine, 9-ethyl-

CAS No: 132-32-1 Catalog No: AG00101R MDL No:MFCD00004964

Product Description

Catalog Number:
AG00101R
Chemical Name:
9H-Carbazol-3-amine, 9-ethyl-
CAS Number:
132-32-1
Molecular Formula:
C14H14N2
Molecular Weight:
210.2744
MDL Number:
MFCD00004964
IUPAC Name:
9-ethylcarbazol-3-amine
InChI:
InChI=1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3
InChI Key:
OXEUETBFKVCRNP-UHFFFAOYSA-N
SMILES:
CCn1c2ccc(cc2c2c1cccc2)N
EC Number:
205-057-7
UNII:
8Q2BG27JBU
UN Number:
2811

Properties

Complexity:
253  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
210.116g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
210.28g/mol
Monoisotopic Mass:
210.116g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
31A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  

Literature

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Rabies diagnosis for developing countries. PLoS neglected tropical diseases 20080301
Enhanced expressions of endothelin-converting enzyme and endothelin receptors in human colonic tissues of Crohn's disease. Journal of clinical biochemistry and nutrition 20080301
Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer. British journal of cancer 20080226
Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer. British journal of cancer 20080212
The role of bystin in embryo implantation and in ribosomal biogenesis. Cellular and molecular life sciences : CMLS 20080101
Markers of subtypes in inflammatory breast cancer studied by immunohistochemistry: prominent expression of P-cadherin. BMC cancer 20080101
Induction of ErbB-3 expression by alpha6beta4 integrin contributes to tamoxifen resistance in ERbeta1-negative breast carcinomas. PloS one 20080101
Defective innate cell response and lymph node infiltration specify Yersinia pestis infection. PloS one 20080101
Expression of the Ladybird-like homeobox 2 transcription factor in the developing mouse testis and epididymis. BMC developmental biology 20080101
B cell response is required for granuloma formation in the early infection of Schistosoma japonicum. PloS one 20080101
The influence of visible light exposure on cultured RGC-5 cells. Molecular vision 20080101
Human retinal Müller cells synthesize collagens of the vitreous and vitreoretinal interface in vitro. Molecular vision 20080101
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PloS one 20080101
Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters. Virology journal 20080101
Topical oestrogen keratinises the human foreskin and may help prevent HIV infection. PloS one 20080101
Galectin-4 controls intestinal inflammation by selective regulation of peripheral and mucosal T cell apoptosis and cell cycle. PloS one 20080101
Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism. Experimental diabetes research 20080101
EGFR and HER2 expression in primary cervical cancers and corresponding lymph node metastases: implications for targeted radiotherapy. BMC cancer 20080101
Prognostic relevance of Centromere protein H expression in esophageal carcinoma. BMC cancer 20080101
A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study. Breast cancer research : BCR 20080101
ES-cell derived hematopoietic cells induce transplantation tolerance. PloS one 20080101
Keratin 8 expression in head and neck epithelia. BMC cancer 20080101
Lysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis media. BMC infectious diseases 20080101
CD44s and CD44v6 expression in head and neck epithelia. PloS one 20080101
Rapid reversal of human intestinal ischemia-reperfusion induced damage by shedding of injured enterocytes and reepithelialisation. PloS one 20080101
Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural development 20080101
In vitro identification and characterization of CD133(pos) cancer stem-like cells in anaplastic thyroid carcinoma cell lines. PloS one 20080101
Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. PloS one 20080101
In vitro and in vivo human herpesvirus 8 infection of placenta. PloS one 20080101
Increased Langerhans cell accumulation after mycobacterial stimuli. Histopathology 20071101
A comparison of immunogenicity and protective immunity against experimental plague by intranasal and/or combined with oral immunization of mice with attenuated Salmonella serovar Typhimurium expressing secreted Yersinia pestis F1 and V antigen. FEMS immunology and medical microbiology 20071001
Pontocerebellar hypoplasia type 2: a neuropathological update. Acta neuropathologica 20071001
PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound. British journal of cancer 20070911
Prognostic implications of cyclin B1, p34cdc2, p27(Kip1) and p53 expression in gastric cancer. Yonsei medical journal 20070831
Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging cell 20070801
Screen-printed electrodes as impedimetric immunosensors for the detection of anti-transglutaminase antibodies in human sera. Analytica chimica acta 20070730
Expression of cyclooxygenase-2 and its relationship to p53 accumulation in colorectal cancers. Yonsei medical journal 20070630
Local delivery of beta interferon using an adeno-associated virus type 5 effectively inhibits adjuvant arthritis in rats. The Journal of general virology 20070601
An impedimetric immunosensor for the detection of autoantibodies directed against gliadins. The Analyst 20070401
Recombinant human erythropoietin alpha modulates the effects of radiotherapy on colorectal cancer microvessels. British journal of cancer 20070312
Stat3 activation in human endometrial and cervical cancers. British journal of cancer 20070226
Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients. British journal of cancer 20070129
c-Met overexpression in inflammatory breast carcinomas: automated quantification on tissue microarrays. British journal of cancer 20070129
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA. Molecular microbiology 20070101
P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling. BMC cancer 20070101
Quantitative image analysis of immunohistochemical stains using a CMYK color model. Diagnostic pathology 20070101
Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo. BMC cancer 20070101
Immunohistochemical expression of melan-A and tyrosinase in uveal melanoma. Journal of carcinogenesis 20070101
Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern. PloS one 20070101
Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Molecular vision 20070101
Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex. Retrovirology 20070101
Overexpressed TP73 induces apoptosis in medulloblastoma. BMC cancer 20070101
STAT5 is an ambivalent regulator of neutrophil homeostasis. PloS one 20070101
Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. Diagnostic pathology 20070101
Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant. Respiratory research 20070101
Design and pre-clinical evaluation of a universal HIV-1 vaccine. PloS one 20070101
Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity. Molecular cancer 20070101
Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow. PloS one 20070101
Expression analysis of the ligands for the Natural Killer cell receptors NKp30 and NKp44. PloS one 20070101
Pleural mesothelioma in a nine-month-old dog. Irish veterinary journal 20070101
The expression of estrogen receptors in hepatocellular carcinoma in Korean patients. Yonsei medical journal 20061231
Inflammation, ECG changes and pericardial effusion: whom to biopsy in suspected myocarditis? Clinical research in cardiology : official journal of the German Cardiac Society 20061101
Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast. Yonsei medical journal 20060630
A selective optical sensor for picric acid assay based on photopolymerization of 3-(N-methacryloyl) amino-9-ethylcarbazole. Analytica chimica acta 20060616
Polycystin-1 expression in fetal, adult and autosomal dominant polycystic kidney. Journal of Korean medical science 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
A comparative study of magnetic-activated cell sorting, cytotoxicity and preplating for the purification of human myoblasts. Yonsei medical journal 20060430
Role of staphylococcal superantigen in atopic dermatitis: influence on keratinocytes. Journal of Korean medical science 20060401
Metallothionein - overexpression as a highly significant prognostic factor in melanoma: a prospective study on 1270 patients. British journal of cancer 20060327
Expression of a disintegrin and metalloprotease (ADAM and ADAMTS) enzymes in human non-small-cell lung carcinomas (NSCLC). British journal of cancer 20060313
Alterations in somatostatin cells and biochemical parameters following zinc supplementation in gastrointestinal tissue of streptozotocin-induced diabetic rats. Acta histochemica et cytochemica 20060302
Angiotensin II type 1 receptor expression in ovarian cancer and its correlation with tumour angiogenesis and patient survival. British journal of cancer 20060227
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. British journal of cancer 20060227
Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS. PLoS medicine 20060201
Evaluation of a direct, rapid immunohistochemical test for rabies diagnosis. Emerging infectious diseases 20060201
B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome. Arthritis research & therapy 20060101
Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. Arthritis research & therapy 20060101
In vitro comparison of antiviral drugs against feline herpesvirus 1. BMC veterinary research 20060101
Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation. Arthritis research & therapy 20060101
Oxidative stress increases Fas ligand expression in endothelial cells. Journal of inflammation (London, England) 20060101
Integrative roles of transforming growth factor-alpha in the cytoprotection mechanisms of gastric mucosal injury. BMC gastroenterology 20060101
Distinct differentiation characteristics of individual human embryonic stem cell lines. BMC developmental biology 20060101
Prostate-specific membrane antigen is undetectable in choroidal neovascular membrane. Journal of carcinogenesis 20060101
Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. Journal of translational medicine 20060101
A gene expression signature associated with survival in metastatic melanoma. Journal of translational medicine 20060101
6A3-5/Osa2 is an early activated gene implicated in the control of vascular smooth muscle cell functions. Journal of biomedicine & biotechnology 20060101
Comparison of apoptosis detection markers combined with macrophage immunostaining to study phagocytosis of apoptotic cells in situ. Biomarker insights 20060101
Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. British journal of cancer 20051212
The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5p, a major yeast drug transporter. Biochemistry 20050719
Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays. British journal of cancer 20050620
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer. British journal of cancer 20050131
Correlation between the tumoral expression of beta3-integrin and outcome in cervical cancer patients who had undergone radiotherapy. British journal of cancer 20050117
Alphavirus replicon particles containing the gene for HER2/neu inhibit breast cancer growth and tumorigenesis. Breast cancer research : BCR 20050101
Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia-reperfusion. Critical care (London, England) 20050101
Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema. Respiratory research 20050101
Accumulation of marginal zone B cells and accelerated loss of follicular dendritic cells in NF-kappaB p50-deficient mice. BMC immunology 20050101
Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers. Respiratory research 20050101
Immunologic testing of xeno-derived osteochondral grafts using peripheral blood mononuclear cells from healthy human donors. BMC musculoskeletal disorders 20050101
Effects of nano particles on antigen-related airway inflammation in mice. Respiratory research 20050101
Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis. Arthritis research & therapy 20050101
25-Hydroxyvitamin D3 1alpha-hydroxylase expression in breast cancer and use of non-1alpha-hydroxylated vitamin D analogue. Breast cancer research : BCR 20050101
Characterization of lymphocyte populations in nonspecific interstitial pneumonia. Respiratory research 20050101
Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases. BMC cancer 20050101
Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo. BMC cancer 20050101
The prognostic effect of VEGF expression in squamous cell carcinoma of the cervix treated with radiation therapy alone. Journal of Korean medical science 20041001
Metabolism of avenanthramide phytoalexins in oats. The Plant journal : for cell and molecular biology 20040801
HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review. British journal of cancer 20040614
Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. British journal of cancer 20040614
Upregulation of glutamate receptors in rat cerebral cortex with neuronal migration disorders. Journal of Korean medical science 20040601
Gene expression profiling of breast cancers with emphasis of beta-catenin regulation. Journal of Korean medical science 20040401
Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancer. British journal of cancer 20040126
Bystander suppression of collagen-induced arthritis in mice fed ovalbumin. Arthritis research & therapy 20040101
Up-regulation of the chemokine CCL21 in the skin of subjects exposed to irritants. BMC immunology 20040101
Immunohistochemical localization of integrin alpha V beta 3 and osteopontin suggests that they do not interact during embryo implantation in ruminants. Reproductive biology and endocrinology : RB&E 20040101
Hepatopulmonary syndrome induced by common bile duct ligation in a rabbit model: correlation between pulmonary vascular dilatation on thin-section CT and angiography and serum nitrite concentration or endothelial nitric oxide synthase (eNOS)1 expression. Korean journal of radiology 20040101
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. Respiratory research 20040101
Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment. British journal of cancer 20030915
Structure-activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres. Bioorganic & medicinal chemistry letters 20030616
Inhibition of epidermoid carcinoma A431 cell growth and angiogenesis in nude mice by early and late treatment with a novel dextran derivative. British journal of cancer 20030616
Fully automated assessment of inflammatory cell counts and cytokine expression in bronchial tissue. American journal of respiratory and critical care medicine 20030601
Expression of somatostatin receptor type-2 (sst2A) in immature porcine Leydig cells and a possible role in the local control of testosterone secretion. Reproductive biology and endocrinology : RB&E 20030101
Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis. Arthritis research & therapy 20030101
Detection of antibody-forming cells directed against Newcastle disease virus and their immunoglobulin class by double immunoenzyme histochemistry. Avian diseases 20030101
High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis. Arthritis research & therapy 20030101
In utero recombinant adeno-associated virus gene transfer in mice, rats, and primates. BMC biotechnology 20030101
Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immunohistochemical and genetic features: implications for tumor progression and invasion. Breast cancer research : BCR 20030101
Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis. British journal of cancer 20021202
Expression of cyclooxygenase-2 (COX-2) in tumour and stroma compartments in cervical cancer: clinical implications. British journal of cancer 20021104
Secreted and tumour targeted human carboxylesterase for activation of irinotecan. British journal of cancer 20020909
Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity. Journal of medicinal chemistry 20020801
Activity staining of plasma amine oxidase after polyacrylamide gel electrophoresis and its application to natural inhibitor screening. Electrophoresis 20020801
Protein expression profiles indicative for drug resistance of non-small cell lung cancer. British journal of cancer 20020729
Tumour microvessel density as predictor of chemotherapy response in breast cancer patients. British journal of cancer 20020617
Early inflammatory markers in elicitation of allergic contact dermatitis. BMC dermatology 20020101
Zinc and Manduca sexta hemocyte functions. Journal of insect science (Online) 20020101
Heat shock protein hyperexpression on chorioretinal layers after transpupillary thermotherapy. Investigative ophthalmology & visual science 20011101
A new rapid acetylcholinesterase histochemical method for the intraoperative diagnosis of Hirschsprung's disease and intestinal neuronal dysplasia. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20011001
Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. Lancet (London, England) 20010526
A new rapid immunohistochemical staining technique using the EnVision antibody complex. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20010501
Measurement of cytokine and adhesion molecule expression in synovial tissue by digital image analysis. Annals of the rheumatic diseases 20010301
Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical study. BMC cancer 20010101
Staphylococcal peptidoglycans induce arthritis. Arthritis research 20010101

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